List of @tome entries for [NR_ZEBRAFISH_I50_201601] :


Volume and Hydrophobicity (binding site) are calculated from the 5 best predicted complexes.

Binding site residus color:Hydrophilic / Neutral / Hydrophobic / Very Hydrophobic (PH=7)

Text file for stat:Predicted_BSiteNR_ZEBRAFISH_I50_201601.txt

Text file for stat:Predicted_BSiteNR_ZEBRAFISH_I50_201601.distrib

Text file for stat:Predicted_BSiteNR_ZEBRAFISH_I50_201601.fasta

Text file for stat:Predicted_BSiteNR_ZEBRAFISH_I50_201601.muscle

CptReceptorsVolume (FPocket)Hydrophobicity score(FPocket) Binding Site Prediction on 5 best models [Protein/Ligand Contacts <4A] Ligands selected for calculation [theoretical Kd Limit=3]
1 Z_NR1A1_THAA 692 (s=60) 32 (s=3) --------------------------------------------------------------------------------------------------------MEN---------TEQEHNLPEGDETQWPNGVKRKRKNSQCSMNS-TSDKSISV--PGYVPSYL-------------------------------EKDEPCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDSCCIIDKITRNQCQLCRFRKCISVGMAMDLVLDDSKRVAKRRLIEENREKRKKEEIVKT-LHNRPEPTVSEWELIRMVTEAHRHTN--------------AQGPHWKQKRKFLPEDIGQSPAP--------------TSDNDKV--------------------DLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-SGEMAVSREQLKNGG--------------LGVVSDAIF-DLGKSLSQFNLDDSEVALLQAVLLMSSDR--------SGLTCVEKIEKCQEMYLLAFEHYINH---RKHNISHFWPKLLMKVTNLRMIGACHASRFLHMKVEC-PTEL-FPPLFLEVFEDQEGST--------------GV-------------------------AAQEDGSCLR------------------------------------------ G24_B_2(1Q4X)[-9.9]; PFA_C_3(1N46)[-9.5]; PFA_D_4(1N46)[-9.4]; 4HY_A_4(2PIN)[-9.0]; 4HY_A_3(3D57)[-8.9];
2 Z_NR1A2_THB 673 (s=74) 31 (s=3) --------------------------------------------------------------------------------------------------------------------------------------MSEQADKCNSRWKD-EAMQ------NGYIPSYL-------------------------------DKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENRERRRREELQKT-VWDRPEPTQEEWEMIRVVTEAHMATN--------------AQGNHWKQKRKFLSAVGVKEAKPEDIGSAPIVN----APEGNKV--------------------DIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-NGEMAVTRGQLKNGG--------------LGVVSDAIF-DLGVSLSSFNLDDSEVALLQAVILLSSDR--------PGLTSVERIERCQEEFLLAFEHYINY---RKHKVAHFWPKLLMKVTDLRMIGACHASRFLHMKVEC-PTEL-FPPLFLEVFED-------------------------------------------------------------------------------------------------- G24_B_2(1Q4X)[-9.9]; PFA_C_3(1N46)[-9.6]; PFA_D_4(1N46)[-9.4]; 4HY_A_4(2PIN)[-9.1]; 4HY_A_3(3D57)[-9.1];
3 Z_NR1B1_RARAA 830 (s=35) 32 (s=3) -----------------------------------------------------------------------------------------MYESVDVNPFLMMDYYNQ---------SRGCLIPDKMPH-PFSSSIRHQHWSGSNHS---IETQSTSS--EEIVPSPP-------------------------SPPPPPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM--VYTCHREKNCIINKVTRNRCQYCRLQKCLEVGMSKESVRND-------------RNKKKKEEKKPE-CTENYTLSPDTEQMIDRVRKAHQETF-----------------PSLCQLGKYTTS----------------------NSSERRV------------------ALDVDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTF-SDGLTLNRTQMHNAG--------------FGPLTDLVF-AFANQLLPLEMDDAETGLLSAICLLCGDR--------QDLEQADKVDVLQEPLLEALKIYVRN---RRPHKPHMFPKMLMKITDLRSISAKGAERVITLKMEI-PGSM--PPLIQEMLENSEGLE------SSSGAQGSRA-------------------------SATTPGSCSPSLSPNSAQSSPPTQSP-------------------------- JYI_B_6(4JYI)[-11.9]; EQO_B_5(3KMZ)[-11.5]; 1NY_B_7(4JYG)[-11.5]; JYI_A_5(4JYI)[-11.4]; 1NY_A_5(4JYG)[-11.3];
4 Z_NR1B1_RARAB 949 (s=60) 31 (s=3) ----------------------------------------------------------------------------------MYESVDVVGLTPSPNPFLSMDYYHQ---------NRGCLIPDKGLVSGAARGFRNPHWSGSNHS---VETQSTSS--EEIVPSPP-------------------------SPPPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM--VYTCHREKSCIINKVTRNRCQYCRLQKCLEVGMSKESVRND-------------RNKRKKDDKKQE-CLENYVLSPDTEKMIEQVRKAHQETF-----------------PSLCQLGKYTTN----------------------NSADHRV------------------ALDVDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPDQDTMTF-SDGLTLNRTQMHNAG--------------FGPLTDLVF-AFANQLLPLEMDDAETGLLSAICLLCGDR--------QDLEQSDKVDELQEPLLEALKIYVRN---RRPHKPHMFPKMLMKITDLRSISAKGAERVITLKMEI-PGSM--PPLIQEMLENSEGLEGGGSKGAGGGGGGGGG-------------------------KGAPPGSCSPSLSPSSAHSSPSAHSP-------------------------- JYI_B_6(4JYI)[-11.9]; EQO_B_5(3KMZ)[-11.5]; 1NY_B_7(4JYG)[-11.5]; JYI_A_5(4JYI)[-11.4]; 1NY_A_5(4JYG)[-11.3];
5 Z_NR1B3_ARGA 832 (s=67) 36 (s=3) ------------------------------------------------------------------------------------------MFDCMEALGMGPRQLYD---------VTNRGACMLRKASPFYAGLDPFAWTGTASVRS-VETQSTSS--EEMVPSSP-------------------------SPPPPPRVYKPCFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNM--VYTCHRDKNCQINKVTRNRCQYCRLQKCFEVGMSKEAVRND-------------RNKKKKDVKDEVIPPESYELSGELEELVNKVSKAHQETF-----------------PSLCQLGKYTTN----------------------SSSDHRI------------------QLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTTLTIADQITLLKSACLDILMLRICTRYTPEQDTMTF-SDGLTLNRTQMHNAG--------------FGPLTDLVF-AFAGQLLPLEMDDTETGLLSAICLICGDR--------MDLEEPERVDRLQEPLLEALKIYARR---RRPNKPHMFPRMLMKITDLRGISTKGAERAITLKMEI-PGPM--PPLIREMLENPEAFEDQSESTEKKPEPEPPAPPPPALLTMKKEQ----EDEDDSWATENGSEPSPEEEDDDDEDGEEERGT-DSDGEAWGGQEPNADVSRKSHGGRAQ 184_A_2(1FCX)[-11.4]; EQO_B_5(3KMZ)[-11.4]; JYI_B_6(4JYI)[-11.3]; 564_A_2(1FCY)[-11.3]; 564_A_2(1FCY)[-11.3];
6 Z_NR1B3_RARGB 786 (s=103) 37 (s=3) -------------------------------------------------------------------------------------------------------MRDV---------FREATPMTCRSPLPDLRDMMEKLTVFEPTIDSTVETQSTSS--EEMIPSSP-------------------------SPPPPPRVYKPCFVCQDKSSGYHYGVSSCEGCKGFFRRSIQKNM--VYTCHRDKNCQINKVTRNRCQYCRLRKCFEVGMSKEAVRND-------------RNKKKKDVKEEVVLPESYELSGELEELVNKVSKAHRETF-----------------PSLCQLGKYTTN----------------------SSADHRV------------------QLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTSLTIADQITLLKSACLDILMLRICTRYTPEQDTMTF-SDGLTLNRTQMHNAG--------------FGPLTDLVF-AFAGQLLPLEMDDTETGLLSAICLICGDR--------MDLEEPHRVDQLQEPLLEALKIYARR---RRPNKPHMFPRMLMKVTDLRGISTKGAERAITLKMEI-PGPM--PPLIREMLENPEIFEDSSDSNDSGAAAVVPA---PNIKRMGQRQAAWVKGERPEWVRGRRRGSKSRYKAGFKAGKARSRDSPDNNGEIRQGDERSEMSVRAEQDFALE EQO_B_5(3KMZ)[-11.4]; 184_A_2(1FCX)[-11.4]; 564_A_2(1FCY)[-11.3]; JYI_B_6(4JYI)[-11.3]; 564_A_2(1FCY)[-11.3];
7 Z_NR1C1_PPARa2 1497 (s=232) 39 (s=4) -----------------------------------------------------------------------------MVDMENRYRPPSPLDDSVLDSALFVRGMEE---------LRDISQSMDEDALSSFEMTENQSGLGSGSESS-TELDALTP--ASSPSSGVYGCPVGQ------------------DEFTSTSLNLECRVCSDRASGYHYGVHACEGCKGFFRRTIRLKL--EYD-KCERRCKIQKKNRNKCQYCRFQKCLSVGMSHNAIRFG-------RMPQSEKLRLKAEILTGE-----RDVEDDQKTLAKQIYEAYVKNF-----------------NMNKSKARTILTGKTS-TPPFVIHDMETLQ----LAEQTFVAKMMGSCGGLLNK-----DPEVRIFHCCQCTSVETVTELTEFAKSVPGFSNLDLNDQVTLLKYGVHEALFAMLASCMNKDGLLVAY-GSGF-ITREFLKSLR------------RPFSDMMEPKF-QFAMKFNSLELDDSDLALFVAAIICCGDR--------PGLVNVPHIERMQESIVNVLHLHLKS---NHPDHGFLFPKLLQKLVDLRQLVTEHAQLIQEIKKTE-DTSL--HPLLQEIYRDMY------------------------------------------------------------------------------------------------ 1FA_B_4(2Q5G)[-11.3]; 072_D_8(4PRG)[-11.1]; S44_A_2(2ZNN)[-11.1]; 471_L_12(1KKQ)[-11.0]; 1FA_A_3(2Q5G)[-10.9];
8 Z_NR1C2_PPARb1 1337 (s=169) 41 (s=3) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSCKVQKKSRNKCQFCRFQKCLMLGMSHDAIRYG-------RMPEAEKRKLVAGLLAGE-RGSQNSNESDLKTLAKRVNNAYLKNL-----------------NMTKKKARNILTGKTSASTPFVIHDMDSLV----QAENGLV------WNQVIHGAPPNNEIGVHVFYRCQCTTVETVRELNEFSKSIPGFIDLFLNDQVTLLKYGVHEAIFAMLPSLMNKDGLLVAN-GRGF-VTREFLRSLR------------KPFSEIMEPKF-EFAVKFNALELDDSDLALFVAAIILCGDR--------PGLMNVHQVEKIQDSILQALNQHLQL---NHPDGRFIFPRLLQKLADLRQLVTENAQLVQKIKKTESETSL--HPLLQEIYRDLY------------------------------------------------------------------------------------------------ 1FA_A_3(2Q5G)[-10.9]; 1FA_B_4(2Q5G)[-10.7]; S44_A_2(2ZNN)[-9.9]; RO0_C_3(2FVJ)[-9.8]; HIG_A_3(3R8A)[-9.8];
9 Z_NR1C2_PPARb2 1321 (s=142) 41 (s=3) ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AMCRVCGDKASGFHYGVHACEGCKGFFRRTIRMKL--EYE-RCERACKVQKKSRNKCQYCRFQKCLALGMSHDAIRYG-------RMPEAEKKKLVAGLLAGE--NPQSSSGTDLKTLAKHVNTAYLRNL-----------------NMTKKRARSILTGKTSCTAPFVIHDMDSLW----QAENGLV------WNQ-LNGAPLNKEIGVHVFYRCQCTTVETVRELTEFAKNIPGFVDLFLNDQVTLLKYGVHEAIFAMLPSLMNKDGLLVAN-GKGF-VTREFLRSLR------------KPFSEIMEPKF-EFAVKFNALELDDSDLALFVAAIILCGDR--------PGLMNVKQVEQIQDGILQALDQHLQV---HHPDSSHLFPKLLQKMADLRQLVTENAQLVQMIKKTESETSL--HPLLQEIYRDLY------------------------------------------------------------------------------------------------ 1FA_A_3(2Q5G)[-10.9]; 1FA_B_4(2Q5G)[-10.7]; S44_A_2(2ZNN)[-9.9]; RO0_C_3(2FVJ)[-9.8]; HIG_A_3(3R8A)[-9.8];
10 Z_NR1C3_PPARg 1310 (s=147) 39 (s=4) ------------------------------------------------MLHRRFSVQKASLSADMVDTQTFGWPVGFGLSALELEELEDDTHSLDIKPFSTLDYSSISGIDYENNPTQNDPTPHMMDLTHMYSYRTQENYRTHEPIYR-PEHSSYSPEENTYRAQQIQNSIKLEPESPPQFAENSVSFSKTPEDPSSSSLNIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKL--VYD-HCDLHCRIHKKSRNKCQYCRFQKCLMVGMSHNAIRFG-------RMPQAEKEKLLAEFSSDV--NHMHPESADLRALARHLYESYLKYF-----------------PLTKAKARAILSGKTSDNAPFVIHDMKSLV----EGEQMINCRYMPLHEHRRSDLGIMHEVELRFFHSYQSRSAEAISEVTEFAKSIPGFINLDLNDQVTLLKYGVIEVMIIMISPLMNKDGTLISY-GQIF-MTREFLKSLR------------KPFCEMMEPKF-EFSIKFNMLELDDCDMALFLAVIILSGDR--------PGLLDVKPIEDLQETVLHSLELQLKI---NHPDSLQLFAKVLQKMTDLRQLVTDHVQLIQMMKETEADWSL--HPLLQEIMRDLY------------------------------------------------------------------------------------------------ D30_D_6(3H0A)[-10.2]; 3JX_D_4(4R2U)[-9.8]; SP3_C_3(2G0H)[-9.4]; JJA_A_3(3WMH)[-9.0]; 2PQ_A_3(3GBK)[-9.0];
11 Z_NR1I1_VDRA 1026 (s=47) 46 (s=1) ------------------------------------------------------------------------------------------------------MLTEN---------SAVNSGGKSKCEAGACESRVNGDATSVMDLMA-VSTSATGQ--DEFDRNAP----------------------------------RICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKA--SFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDE----EVQRKKDLIMKRKEEEAARE--ARKPRLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSG---SPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAG-------------HTLELLEPLV-KFQVGLKKLKLHEEEHVLLMAICLLSPDR--------PGVQDHVRIEALQDRLCDVLQAYIRI---QHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQP-EHSMQLTPLVLEVFGSEVS----------------------------------------------------------------------------------------------- DS4_A_2(3W0Y)[-13.5]; TFY_A_2(4ITF)[-13.2]; VHW_A_2(3VHW)[-13.1]; TEY_A_2(4ITE)[-12.9]; 6DS_A_2(3W0C)[-12.8];
12 Z_NR1I1_VDRB 1022 (s=32) 46 (s=1) ------------------------------------------------------------------------------------------------------------------------------------------------MESA-VSTSTQVP--DEFDRNVP----------------------------------RICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKA--SFTCPFNGSCTITKDNRRHCQACRLKRCLDIGMMKEFILTDE----EVQRKKELIQRRKDEEAHRE--AQKPRLSDEQRNIIDTLVDAHHKTYDDSYSDFSRFRPPVREGPVTRSASRAASLHSLSDASSDSFSHSPESGDRKMNLSNLLMMYQEQGLSSSPDSKEED-GSSLSMLPHLADLVSYSIQKVIGFAKMIPGFRELTAEDQIALLKSSAIEVIMLRSNQSFSLEDMSWSCGGPEFKYCVNDVTKAG-------------HTLELLEPLV-KFQVGLKKLNLHEEEHVLLMAICLLSPDR--------PGVQDHVRVEALQDKVSEVLQAYIRA---HHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQP-EHSMQLTPLVLEVFGGQVT----------------------------------------------------------------------------------------------- DS4_A_2(3W0Y)[-13.5]; TFY_A_2(4ITF)[-13.2]; VHW_A_2(3VHW)[-13.1]; TEY_A_2(4ITE)[-12.9]; 6DS_A_2(3W0C)[-12.8];
13 Z_NR2B1_RXRAA 790 (s=46) 41 (s=1) -----------------------------------------------------------------------------MHPSLLSPTSLGPSGSLHSPISTLSSPMNG---------LGSPFSVISSPMGPHSMASPGVGYGPSISPQLNSHMNSVSS--SEDIKPPLGLNGVMKVPAQP-------------SGTPLSLTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL--TYTCRDNKDCVIDKRQRNRCQYCRYQKCLAMGMKREAVQEE---------RQRAKERSENEVESTS--------SANEDMPVEKILEAELAVE-----------------PKTETYIETNVPMPS-------------------NSPNDPV-------------------------TNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILL-ATGLHVHRNSAHSAG--------------VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS--------KGLSNPGEVEALREKVYASLEAYCKH---KYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-DTPI--DTFLMEMLEAPHQMT--------------------------------------------------------------------------------------------- 5TN_A_3(2P1V)[-10.3]; BM6_E_5(1MVC)[-10.2]; 4TN_A_3(2P1U)[-10.0]; BM6_K_11(1MZN)[-9.9]; BM6_J_10(1MZN)[-9.8];
14 Z_NR2B1_RXRAB 812 (s=57) 40 (s=2) ---------------------------------------------------------------------------------------------------------------------------------------MPVPEQKQTVQLS-SPMNAVSS--SEDIKPPLGLNGVMKVPAHRI------------GTLSLSLTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL--TYTCRDNKDCMIDKRQRNRCQYCRYQKCLAMGMKREAVQEE---------RQRAKERSEAEFGG----------CANEDMPVEKILEAELAVE-----------------PKTETYVEANLSPSA-------------------NSPNDPV-------------------------TNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSIAVKDGILL-ATGLHVHRNSAHTAG--------------VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS--------KGLSNPSEVEALRERVYASLEAYCKH---KYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-DTPI--DTFLMEMLEAPHQIT--------------------------------------------------------------------------------------------- 5TN_A_3(2P1V)[-10.3]; BM6_E_5(1MVC)[-10.2]; 4TN_A_3(2P1U)[-10.0]; BM6_K_11(1MZN)[-9.9]; LG2_B_8(1H9U)[-9.8];
15 Z_NR2B2_RXRBA 820 (s=17) 40 (s=2) --------------------------------------------------MGDSRDSRSPDSSSVSSPPSGQRSPPLAPSAAAMTSLPPITSAVNSPISSMGSPFSV---------ISSSLGSPCLPGTPSVGYGPISSPQINSTVSM-SGLHAVSS--SDDVKPPFGLKPLSSH-----------------SPGPMVSQKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL--SYTCRDNKDCLVDKRQRNRCQYCRYQKCLAMGMKREVVQDE-----RQRSVQEERQRNKERDGEVE-----SSSAANEEMPVEKILEAEMAVE-----------------QKTELHADGSSGG---------------------SSPNDPV-------------------------TNICQAADKQLFTLVEWAKRIPHFSELSLDDQVILLRAGWNELLIASFSHRSITVKDGILL-ATGLHVHRNSAHSAGVGAIFDRESAHNAEVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIILFNPDA--------KGLSSPSEVELLREKVYASLEAYCKQ---RYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-DTPI--DTFLMEMLEAPHQLT--------------------------------------------------------------------------------------------- 5TN_A_3(2P1V)[-10.3]; BM6_E_5(1MVC)[-10.2]; 4TN_A_3(2P1U)[-10.0]; BM6_K_11(1MZN)[-9.9]; LG2_B_8(1H9U)[-9.8];
16 Z_NR2B2_RXRBB 813 (s=32) 45 (s=0) -----------------------------------------------------------------------------------MNSLPPSTSAVSSPVSSVDSPLSA---------VSSSIGSPGVPGTPSIGYGPISNSQINSSMSV-SRLHAVSS--SDDVKPPFGLKSVS-------------------GSGPMLSQKRMCAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDL--SYTCRDNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQEE-------------RQKNKERDGDYE-----CSSSANEEMPVEKILEAETAVE-----------------HRTDLHSDAT------------------------GSPNDPV-------------------------TNICQAADKQLFTLVEWAKRVPHFSDVPLDDQVILLRAGWNELLIAAFSHRSISVKDEILL-ATGLHVPKESTHNLGVEAFFDRESSHSAEVGALFDRVLTELVCKMRDMQMDKTELGCLRAIVLFNPDA--------KGLTSSSEVELLREKVYASLESYCKQ---KYPDQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-NTPI--DTFLMEMLESPH------------------------------------------------------------------------------------------------ BM6_E_5(1MVC)[-10.3]; 5TN_A_3(2P1V)[-10.2]; 4TN_A_3(2P1U)[-10.0]; BM6_J_10(1MZN)[-9.9]; BM6_L_12(1MZN)[-9.9];
17 Z_NR2B3_RXRGA 834 (s=40) 41 (s=1) -----------------------------------------------------------MDNNDTYLHLSSSLQVAHGHLSSPPSQPPLSSMVSHHHPSIINGLGSP---------YSVITSSSLGSPSASMPTTSNMGYGALNSPQM-NSLNSVSS--SEDIKPPPGLAGLGSYP----------------CGSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDL--TYTCRDNKDCQIDKRQRNRCQYCRYQKCLAMGMKREAVQEE---------RQRGRERSDNEVDSSS--------SFNEEMPVEKILDAELAVE-----------------PKTEAYMESSMS----------------------NSTNDPV-------------------------TNICQAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSVTVKDGILL-ATGLHVHRSSAHSAG--------------VGSIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDA--------KGLSNPSEVEALREKVYASLEGYTKH---NYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-DTPI--DTFLMEMLEAPHQIT--------------------------------------------------------------------------------------------- 5TN_A_3(2P1V)[-10.3]; BM6_E_5(1MVC)[-10.2]; 4TN_A_3(2P1U)[-10.0]; BM6_K_11(1MZN)[-9.9]; L79_E_5(1RDT)[-9.8];
18 Z_NR2B3_RXRGB 825 (s=27) 38 (s=2) -----------------------------------------------------MDTHDTYLHLHSSPLNSSPSQPPVMSSMVGHPSVISSSRPLPSPMSTLGSSMNG---------LPSPYSVITPSLSSPSISLPSTPSMGFNTLNS-PQMNSLSMNGNEDIKPPPGLAPLGNMSSYQ-------------CTSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDL--TYTCRDIKECLIDKRQRNRCQYCRYQKCLAMGMKREAVQEE---------RQRGKEKSDTEVETTS--------RFNEDMPVDKILDAELSVE-----------------PKTETYTESSPS----------------------NSTNDPV-------------------------TNICHAADKQLFTLVEWAKRIPHFSDLPLDDQVILLRAGWNELLIASFSHRSITVKDGILL-GTGLHVHRSSAHSAG--------------VGSIFNRVLTELVSKMKDMQMDKTELGCLRAIVLFNPDA--------KGLSNSLEVEALREKVYASLETYTKQ---KYPDQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG-DTPI--DTFLMEMLEAPHQIT--------------------------------------------------------------------------------------------- 5TN_A_3(2P1V)[-10.3]; BM6_E_5(1MVC)[-10.2]; 4TN_A_3(2P1U)[-10.1]; BM6_L_12(1MZN)[-9.9]; LG2_A_5(1H9U)[-9.8];
19 Z_NR2F1A
20 Z_NR2F1B
21 Z_NR2F5
22 Z_NR3A1_ESR1 921 (s=141) 52 (s=5) --MYP--------KEEHSAGGISSSV-----------------------NYLDGAYEYPNPTQ------TFGTSSPAEPASVGYYPAPPDPHEEHLQTLGGGSSSPL---------MFAPSSPQLSPYLSHHGGHHTTPH-QVSYYLD-SSSSTVYR--SSVVSSQQAAVGLCEELCSATDRQELYTGSRAAGGFDSGKETRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN--DYVCPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGIRKDR----GGRSVRRERRRSSNEDRDKSSSDQCSRAGVRTTGPQDKRKKRSGGVV-----------------STLCMSPDQVLLLLLGAEPPAVCSRQKHSR----PYTEITM------------------------MSLLTNMADKELVHMIAWAKKVPGFQDLSLHDQVQLLESSWLEVLMIGLIWRSIHSPGKLIF-AQDLILDRSEGECVE-------------GMAEIFDMLL-ATVARFRSLKLKLEEFVCLKAIILINSGAFSFCSSPVEPLMDNFMVQCMLDNITDALIYCISKSGASLQLQSRRQAQLLLLLSHIRHMSNKGMEHLYRMKCKN-RVPL--YDLLLEMLDAQRFQSSGKVQRVWSQSEKNPPSTPTTSSSSS---------------NNSPRGGAAAIQSNGACHSHSPDP---------------------------- IOG_A_2(2IOG)[-11.6]; EZT_A_5(2P15)[-11.4]; AIU_C_3(1XP6)[-11.3]; EZT_B_6(2P15)[-11.3]; AIH_C_3(1XP1)[-10.9];
23 Z_NR3A2_ESR2a 1176 (s=262) 56 (s=3) MSEYPEGDSPLLQLQEVDSGRVGGHILSPIFNSSSPSLPVENHPICIPSPYTDLGHDFS----------TLPFYSP---ALLGYSTSPLSDCSSVRQSL----SPTL---------FWPPHS-HVSSLTLQQQSRLQQNHATSGTWTE-HTPHDHVE--EENSKPLVKRVA---------DTEE------TSVSLRGKADMHYCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHN--DYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGLRRDR----SSYQQRGAQQKRLVRFSGRM---RMTGPRSQEIKSIPRPLSGNEVV-------------------RISLSPEELISRIMEAEPPEIYLMKDMKK----PFTEANV------------------------MMSLTNLADKELVHMISWAKKIPGFVELSLFDQVHLLECCWLEVLMLGLMWRSVNHPGKLIF-SPDLCLSRDESSCVQ-------------GLVEIFDMLL-AATSRFRELKLQREEYVCLKAMILLNSNMCLGSSEGGEDLQSRSKLLCLLDSVTDALVWAISKTGLSFQQRSTRLAHLLMLLSHIRHVSNKGMDHLHCMKMKK-MVPL--YDLLLEMLDAHIMHS----SRLSHSGPRAPA-------------------------AHKDNKSVQEAFPCSSQ--HGP------------------------------ IOG_A_2(2IOG)[-11.1]; AOE_A_2(1HJ1)[-11.0]; AEJ_E_5(1XQC)[-10.5]; L4G_B_2(2AYR)[-10.4]; C3D_C_3(2OUZ)[-10.4];
24 Z_NR3A2_ESR2b 990 (s=208) 48 (s=1) MSSSP-GPAPVLDSSKADRG-ASPALLPRLYAS---PLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLV---PL----SPTI---------LWPPHSLHCPPPLAYSETR------SHSAWEE-AKTHTLSQ--SSSVLSHTKLLG---------QQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHN--DYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGVRRE------RCSYRGARHRRNPQIRDSS--GGVVGLRGQSQQHLEFPLSPSQHLF---------PSGGRAEGRALNYSPEQLVSCILEAEPPQIYLREPVKK----PYTEASM------------------------MMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGKLIF-TPDLKLNREEGNCVE-------------GIMEIFDMLL-ATTSRFRELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKN-VVLL--YDLLLEMLDANASQS----SRMLEDRQQSPE-------------------------NLHTSRPQPDLKDSDQETPHSPRAEEMVNKTLHSSLLREDMDTN-------- EZT_B_6(2P15)[-11.6]; AOE_A_2(1HJ1)[-11.5]; AIU_C_3(1XP6)[-11.4]; AIT_C_3(1XPC)[-11.2]; AIT_C_3(1XPC)[-11.2];
25 Z_NR6A1A_GCNFA
26 Z_NR6A1B_GCNFB