@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : S8EP32_TOXGM: (2017-06-15 )
MGRRKSVLYFYDENIGNFHYGPSHPMKPHRVRMTHDLIQAYDLLQSMDIVKPLKPAVEDLTRFHANDYVDFLRASAQSRLEASLSPRPFLFFSPSPAAARSASRPSPPPQAEGAAAVSAGASGVSVVQSGSGSRVRSTLHPLRSESRSVSPATSAFDSRVPPEAVGADALSSTDARGRTPPKSLGADLGPGGWSRAATQKPPFLQASSGDGAHGPLGLQCPSAAEETGTGGQAPAWAPPGVSPSLRRGEDANGLLSSAAFDEEVAAPPVPLSSSLADQMARFNVGEDCPVFDGLWEYCQTYSGGSIEGARRVVRGEYDWAINWAGGLHHGKKHEASGFCYINDCVLAALEFLRFKHRVLYVDVDIHHGDGVEEAFYTSPRVLCCSFHKYGDYFPGTGALDDVGIDEGLGYSVNVPLSEGVDDAMYTRLFRQVMDMIMESYRPEAVVLQCGADSLSGDRLGCFNLSIDGHSEAVRYFCSKDVPALFLGGGGYTLRNVPRCWATETGYVLGLSLNPNIPEESEYVGYYGPDSTLHVRTSNMENRNEDSYVQHVIERISQTLKDHVRPVGAQISANYFLDDSVMDKSDQIRALLADEEEEKAMDSSGDAEDADGAGRFEEISNRNRG

Atome Classification :

(108 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.--......270------.........280.--------------..-....290.......300...--------....310......--.320.......330.......340......---.350...--.--..---.360.......370.......380.......--390--.-..-..--...400.........410......-.-420---...----.....430.......440.......450....--...460.......470.......480........490.......500.......510.......---520.......530.....-.-.540.......550.......560.......570.......580.......590.......600.......610.......620..
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MGRRKSVLYFYDENIGNFHYGPSHPMKPHRVRMTHDLIQAYDLLQSMDIVKPLKPAVEDLTRFHANDYVDFLRASAQSRLEASLSPRPFLFFSPSPAAARSASRPSPPPQAEGAAAVSAGASGVSVVQSGSGSRVRSTLHPLRSESRSVSPATSAFDSRVPPEAVGADALSSTDARGRTPPKSLGADLGPGGWSRAATQKPPFLQASSGDGAHGPLGLQCPSAAEETGTGGQAPAWAPPGVSPSLRRGEDANGLLSSAAFDEE--VAAPPVP--------LSSSLADQMARFN--------------VG-EDCPVFDGLWEYCQTYSGGS--------IEGARRVVRGEYD--WAINWAGGLHHGKKHEASGFCYINDCVLAA---LEFLRFK--H--RV---LYVDVDIHHGDGVEEAFYTSPRVLCCSFHKY--G-D--Y-FP-GT--GALD--DVGIDEGLGYSVNVPLSE-G-VD----DAM----YTRLFRQVMDMIMESYRPEAVVLQCGADSLSG--DRLGCFNLSIDGHSEAVRYFCSKDV-PALFLGGGGYTLRNVPRCWATETGYVLGLSLNPNIPEE---SEYVGYYGPDSTLHVRTS-N-MENRNEDSYVQHVIERISQTLKDHVRPVGAQISANYFLDDSVMDKSDQIRALLADEEEEKAMDSSGDAEDADGAGRFEEISNRNRG
164 HHSearch 97.3553%-114 - C2 - - 4LY1 HDAC2_HUMAN A:[2-368] ---KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPY----NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLRMLP-------------------------------------------------------------
160 HHSearch 96.6650%-112 - C2 - - 4BKX HDAC1_HUMAN B:[8-376] ---RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VASAVKLNKQQTD--IAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNYPLRD-G-ID----DES----YEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIKGHAKCVEFVKSFNL-PMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPY----NDYFEYFGPDFKLHISPS-N-MTNQNTNEYLEKIKQRLFENLRMLPHA-----------------------------------------------------------
163 HHSearch 92.3550% -70 - C2 - - 4A69 HDAC3_HUMAN A:[2-370] ---AKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKSLNAFN--------------VG-DDCPVFPGLFEFCSRYTGAS--------LQGATQLNNKICD--IAINWAGGLHHAKKFEASGFCYVNDIVIGI---LELLKYH--P--RV---LYIDIDIHHGDGVQEAFYLTDRVMTVSFHKY--G-NY-F-FP-GT--GDMY--EVGAESGRYYCLNVPLRD-G-ID----DQS----YKHLFQPVINQVVDFYQPTCIVLQCGADSLGC--DRLGCFNLSIRGHGECVEYVKSFNI-PLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPY----SEYFEYFAPDFTLHPDVSTR-IENQNSRQYLDQIRQTIFENLKMLN-------------------------------------------------------------
23 PsiBlast_CBE 84.7456%-118 - C2 - - 5IX0 HDAC2_HUMAN C:[80-366] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
4 PsiBlast_PDB 84.7256%-116 - C2 - - 5IX0 HDAC2_HUMAN A:[80-366] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
24 PsiBlast_CBE 84.7156%-118 - C2 - - 5IX0 HDAC2_HUMAN B:[80-366] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
25 PsiBlast_CBE 84.6256%-119 - C2 - - 5IWG HDAC2_HUMAN C:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
162 HHSearch 84.3938% -73 - C2 - - 5DC8 HDAC8_HUMAN A:[14-376] ----LVPVYIYSPEYVSMC--DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPDSIEYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWAHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--S-PG-F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPD----HEFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHV--------------------------------------------------------------
5 PsiBlast_PDB 84.3056%-116 - C2 - - 4LXZ HDAC2_HUMAN A:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
27 PsiBlast_CBE 84.1356%-115 - C2 - - 4LY1 HDAC2_HUMAN C:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
26 PsiBlast_CBE 84.1356%-116 - C2 - - 5IWG HDAC2_HUMAN B:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
7 PsiBlast_PDB 83.9556%-117 - C2 - - 5IWG HDAC2_HUMAN A:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
22 PsiBlast_CBE 83.9456%-117 - C2 - - 3MAX HDAC2_HUMAN B:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
21 PsiBlast_CBE 83.6956%-114 - C2 - - 3MAX HDAC2_HUMAN C:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
28 PsiBlast_CBE 83.4256%-118 - C2 - - 4LY1 HDAC2_HUMAN B:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
29 PsiBlast_CBE 83.0156%-113 - C2 - - 4LXZ HDAC2_HUMAN C:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
30 PsiBlast_CBE 82.3256%-114 - C2 - - 4LXZ HDAC2_HUMAN B:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
6 PsiBlast_PDB 82.3156%-117 - C2 - - 4LY1 HDAC2_HUMAN A:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
3 PsiBlast_PDB 81.5056%-115 - C2 - - 3MAX HDAC2_HUMAN A:[79-365] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VAGAVKLNRQQTD--MAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNFPMRD-G-ID----DES----YGQIFKPIISKVMEMYQPSAVVLQCGADSLSG--DRLGCFNLTVKGHAKCVEVVKTFNL-PLLMLGGGGYTIRNVARCWTYETAVALDCEI-PNELPY---NDYFEYFGPDFKLHISPS-N-MTNQNTPEYMEKIKQRLFENLR----------------------------------------------------------------
1 PsiBlast_PDB 80.6955% -93 - C2 - - 4BKX HDAC1_HUMAN B:[85-376] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VASAVKLNKQQTD--IAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNYPLRD-G-ID----DES----YEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIKGHAKCVEFVKSFNL-PMLMLGGGGYTIRNVARCWTYET----AVALDTEIPNELPYNDYFEYFGPDFKLHISPS-N-MTNQNTNEYLEKIKQRLFENLRMLPHA-----------------------------------------------------------
2 PsiBlast_PDB 80.4256% -95 - C2 - - 5ICN HDAC1_HUMAN B:[85-371] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYSKQMQRFN--------------VG-EDCPVFDGLFEFCQLSTGGS--------VASAVKLNKQQTD--IAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYH--Q--RV---LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--G-E--Y-FP-GT--GDLR--DIGAGKGKYYAVNYPLRD-G-ID----DES----YEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIKGHAKCVEFVKSFNL-PMLMLGGGGYTIRNVARCWTYET----AVALDTEIPNELPYNDYFEYFGPDFKLHISPS-N-MTNQNTNEYLEKIKQRLFENLR----------------------------------------------------------------
183 Fugue 75.5437% -20 - C2 - - 4QA5 HDAC8_HUMAN A:[14-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVPVYIYSPEYVSMCDSLAKIP-----------KRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDTFSFTSKVMTVSLHKF--S-PG-F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPD----HEFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
8 PsiBlast_PDB 75.0252% -56 - C2 - - 4A69 HDAC3_HUMAN A:[81-367] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTKSLNAFN--------------VG-DDCPVFPGLFEFCSRYTGAS--------LQGATQLNNKICD--IAINWAGGLHHAKKFEASGFCYVNDIVIGI---LELLKYH--P--RV---LYIDIDIHHGDGVQEAFYLTDRVMTVSFHKY--G-N--YFFP-GT--GDMY--EVGAESGRYYCLNVPLRD-G-ID----DQS----YKHLFQPVINQVVDFYQPTCIVLQCGADSLGC--DRLGCFNLSIRGHGECVEYVKSFNI-PLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELP-Y---SEYFEYFAPDFTLHPDVS-TRIENQNSRQYLDQIRQTIFENLK----------------------------------------------------------------
31 PsiBlast_CBE 73.8952% -54 - C2 - - 4A69 HDAC3_HUMAN B:[81-367] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTKSLNAFN--------------VG-DDCPVFPGLFEFCSRYTGAS--------LQGATQLNNKICD--IAINWAGGLHHAKKFEASGFCYVNDIVIGI---LELLKYH--P--RV---LYIDIDIHHGDGVQEAFYLTDRVMTVSFHKY--G-N--YFFP-GT--GDMY--EVGAESGRYYCLNVPLRD-G-ID----DQS----YKHLFQPVINQVVDFYQPTCIVLQCGADSLGC--DRLGCFNLSIRGHGECVEYVKSFNI-PLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELP-Y---SEYFEYFAPDFTLHPDVS-TRIENQNSRQYLDQIRQTIFENLK----------------------------------------------------------------
44 PsiBlast_CBE 72.5142% -57 - C2 - - 4RN1 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG---CPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
87 PsiBlast_CBE 71.8641% -61 - C2 - - 5DC8 HDAC8_HUMAN A:[95-376] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWAHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHV--------------------------------------------------------------
68 PsiBlast_CBE 71.8241% -61 - C2 - - 4QA5 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDTFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
79 PsiBlast_CBE 71.7741% -58 - C2 - - 3EWF HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHAAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
32 PsiBlast_CBE 71.7742% -60 - C2 - - 4QA3 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANMARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
67 PsiBlast_CBE 71.5841% -62 - C2 - - 5DC6 HDAC8_HUMAN A:[95-376] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVNLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHV--------------------------------------------------------------
61 PsiBlast_CBE 71.5642% -56 - C2 - - 4QA2 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQNCESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
78 PsiBlast_CBE 71.4541% -58 - C2 - - 3EWF HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHAAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
82 PsiBlast_CBE 71.3841% -62 - C2 - - 5DC7 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVALDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
83 PsiBlast_CBE 71.3741% -61 - C2 - - 5DC7 HDAC8_HUMAN A:[95-376] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVALDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHV--------------------------------------------------------------
51 PsiBlast_CBE 71.3141% -59 - C2 - - 4QA7 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDR----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
66 PsiBlast_CBE 71.3041% -61 - C2 - - 5DC6 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVNLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
76 PsiBlast_CBE 71.2741% -57 - C2 - - 3EWF HDAC8_HUMAN D:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHAAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
62 PsiBlast_CBE 71.2641% -61 - C2 - - 5D1C HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQG-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
73 PsiBlast_CBE 71.2541% -58 - C2 - - 3MZ7 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YLCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
77 PsiBlast_CBE 71.2241% -58 - C2 - - 3EWF HDAC8_HUMAN C:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHAAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
34 PsiBlast_CBE 71.1542% -59 - C2 - - 1T64 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
85 PsiBlast_CBE 70.9741% -57 - C2 - - 4QA0 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFFYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
43 PsiBlast_CBE 70.9742% -58 - C2 - - 4RN2 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
64 PsiBlast_CBE 70.8141% -58 - C2 - - 3F06 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YACPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
71 PsiBlast_CBE 70.7541% -57 - C2 - - 5D1B HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGEAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
56 PsiBlast_CBE 70.6941% -57 - C2 - - 5DC5 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVNLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
65 PsiBlast_CBE 70.6841% -59 - C2 - - 3F06 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YACPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
74 PsiBlast_CBE 70.6541% -58 - C2 - - 3MZ6 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YLCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
40 PsiBlast_CBE 70.6142% -55 - C2 - - 3F07 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
45 PsiBlast_CBE 70.5442% -56 - C2 - - 4RN1 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
39 PsiBlast_CBE 70.4342% -54 - C2 - - 3F0R HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
80 PsiBlast_CBE 70.3941% -59 - C2 - - 4QA6 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQNCESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
84 PsiBlast_CBE 70.3841% -59 * C2 * - 4QA0 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFFYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
72 PsiBlast_CBE 70.3641% -56 - C2 - - 3EW8 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YLCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
54 PsiBlast_CBE 70.3541% -57 - C2 - - 3EZP HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YNCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
35 PsiBlast_CBE 70.3242% -58 - C2 - - 3RQD HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
69 PsiBlast_CBE 70.3141% -58 - C2 - - 4QA5 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDTFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
38 PsiBlast_CBE 70.2642% -58 - C2 - - 3F0R HDAC8_HUMAN C:[85-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
55 PsiBlast_CBE 70.2041% -58 - C2 - - 3EZP HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YNCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
46 PsiBlast_CBE 70.1642% -59 - C2 - - 4RN0 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
42 PsiBlast_CBE 70.0542% -56 - C2 - - 2V5X HDAC8_HUMAN A:[95-374] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLK----------------------------------------------------------------
50 PsiBlast_CBE 69.9041% -57 - C2 - - 2V5W HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
33 PsiBlast_CBE 69.8942% -56 - C2 - - 1W22 HDAC8_HUMAN B:[85-374] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLK----------------------------------------------------------------
37 PsiBlast_CBE 69.8142% -57 - C2 - - 5BWZ HDAC8_HUMAN B:[85-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
70 PsiBlast_CBE 69.7941% -58 - C2 - - 5D1B HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGEAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
75 PsiBlast_CBE 69.6241% -58 - C2 - - 3MZ4 HDAC8_HUMAN A:[85-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YLCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
52 PsiBlast_CBE 69.6241% -56 - C2 - - 3EZT HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YECPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
81 PsiBlast_CBE 69.6141% -59 - C2 - - 4QA6 HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQNCESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
53 PsiBlast_CBE 69.4441% -57 - C2 - - 3EZT HDAC8_HUMAN A:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YECPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
41 PsiBlast_CBE 69.3042% -57 - C2 - - 2V5X HDAC8_HUMAN B:[95-374] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLK----------------------------------------------------------------
49 PsiBlast_CBE 69.0741% -57 - C2 - - 2V5W HDAC8_HUMAN B:[95-376] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHV--------------------------------------------------------------
36 PsiBlast_CBE 68.5142% -58 - C2 - - 3MZ3 HDAC8_HUMAN B:[95-377] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYG--------------LG-YDCPATEGIFDYAAAIGGAT--------ITAAQCLIDGMCK--VAINWSGGWHHAKKDEASGFCYLNDAVLGI---LRLRRKF--E--RI---LYVDLDLHHGDGVEDAFSFTSKVMTVSLHKF--SPG--F-FP-GT--GDVS--DVGLGKGRYYSVNVPIQD-G-IQ----DEK----YYQICESVLKEVYQAFNPKAVVLQLGADTIAG--DPMCSFNMTPVGIGKCLKYILQWQL-ATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDH----EFFTAYGPDYVLEITPS-C-RPDRNEPHRIQQILNYIKGNLKHVV-------------------------------------------------------------
125 PsiBlast_CBE 48.0133% -46 - C2 - - 5EF8 ? A:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
130 PsiBlast_CBE 47.8633% -47 - C2 - - 5EEM ? B:[139-332] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
102 PsiBlast_CBE 47.7736% -20 - C2 - - 1C3S ? A:[85-271] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYN--------------IGGYENPVSYAMFTGSSLATGST--------VQAIEEFLKG--N--VAFNPAGGMHHAFKSRANGFCYINNPAVG----IEYLRKKGFK--RI---LYIDLDAHHCDGVQEAFYDTDQVFVLSLHQS--P-E--YAFPFEK--GFLE--EIGEGKGKGYNLNIPLPK-G-LN----DNE----FLFALEKSLEIVKEVFEPEVYLLQLGTDPLLE--DYLSKFNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
120 PsiBlast_CBE 47.5533% -46 - C2 - - 5EFH ? A:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
123 PsiBlast_CBE 47.3933% -45 - C2 - - 5EFB ? D:[139-331] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
127 PsiBlast_CBE 47.2433% -47 - C2 - - 5EF7 ? A:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
132 PsiBlast_CBE 47.0533% -47 - C2 - - 5EEK ? A:[139-331] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
124 PsiBlast_CBE 47.0033% -45 - C2 - - 5EF8 ? B:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
103 PsiBlast_CBE 46.8336% -20 - C2 - - 1C3R ? B:[85-271] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYN--------------IGGYENPVSYAMFTGSSLATGST--------VQAIEEFLKG--N--VAFNPAGGMHHAFKSRANGFCYINNPAVG----IEYLRKKGFK--RI---LYIDLDAHHCDGVQEAFYDTDQVFVLSLHQS--P-E--YAFPFEK--GFLE--EIGEGKGKGYNLNIPLPK-G-LN----DNE----FLFALEKSLEIVKEVFEPEVYLLQLGTDPLLE--DYLSKFNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
135 PsiBlast_CBE 46.2932% -45 - C2 - - 5EFK ? B:[139-330] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGFNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
128 PsiBlast_CBE 46.2933% -44 - C2 - - 5EEN ? B:[139-333] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
116 PsiBlast_CBE 46.2933% -46 - C2 - - 5G0J ? A:[536-726] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
117 PsiBlast_CBE 46.2433% -45 - C2 - - 5G0H ? A:[536-726] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
152 PsiBlast_CBE 45.7432% -49 - C2 - - 5EFN ? A:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HAAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDG-A--F-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
104 PsiBlast_CBE 45.7236% -20 - C2 - - 1C3R ? A:[85-271] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYN--------------IGGYENPVSYAMFTGSSLATGST--------VQAIEEFLKG--N--VAFNPAGGMHHAFKSRANGFCYINNPAVG----IEYLRKKGFK--RI---LYIDLDAHHCDGVQEAFYDTDQVFVLSLHQS--P-E--YAFPFEK--GFLE--EIGEGKGKGYNLNIPLPK-G-LN----DNE----FLFALEKSLEIVKEVFEPEVYLLQLGTDPLLE--DYLSKFNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
126 PsiBlast_CBE 45.6433% -47 - C2 - - 5EF7 ? B:[139-331] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
119 PsiBlast_CBE 45.1933% -46 - C2 - - 5EFH ? D:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
129 PsiBlast_CBE 45.0533% -45 - C2 - - 5EEN ? A:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRY--E-DGAF-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
151 PsiBlast_CBE 44.9532% -48 - C2 - - 5EFN ? B:[139-329] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HAAEKDTACGFCFFNTAALTARYAQSITRES--L--RV---LIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDG-A--F-FP-NSEDANYD--KVGLGKGRGYNVNIPWNG-GKMG----DPE----YMAAFHHLVMPIAREFAPELVLVSAGFDAARG--DPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLG------------------------------------------------------------------------------------------------------------------------
107 PsiBlast_CBE 44.6234% -63 - C2 - - 5A2S B:[94-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLGSLASVFVRLP--------------CG-GVGVDSDTIWN--EVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPG-HHAEESTPMGFCYFNSVAVAAKL-LQQRLSV--S--KI---LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDG-N--F-FP-GS--GAPD--EVGTGPGVGFNVNMAFTG-G-LDPPMGDAE----YLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
159 PsiBlast_CBE 44.0432% -49 - C2 - - 5EEF ? A:[139-283] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAQADKMNGFCMFNNLAIAA----RYAQKR--H--RVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDG-S--F-WP-HL--KESDSSSVGSGAGQGYNINLPWNKVG-ME----SGD----YITAFQQLLLPVAYEFQPQLVLVAAGFDAVIG--DPKGGMQVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
105 PsiBlast_CBE 43.0134% -59 - C2 - - 2VQM A:[94-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLGSLASVFVRLP--------------CG-GVGVDSDTIWN--EVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPG-HHAEESTPMGFCYFNSVAVAAKL-LQQRLSV--S--KI---LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDG-N--F-FP-GS--GAPD--EVGTGPGVGFNVNMAFTG-G-LDPPMGDAE----YLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
158 PsiBlast_CBE 42.9732% -48 - C2 - - 5EEF ? B:[139-283] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAQADKMNGFCMFNNLAIAA----RYAQKR--H--RVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDG-S--F-WP-HL--KESDSSSVGSGAGQGYNINLPWNKVG-ME----SGD----YITAFQQLLLPVAYEFQPQLVLVAAGFDAVIG--DPKGGMQVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
108 PsiBlast_CBE 42.9634% -58 - C2 - - 5A2S HDAC4_HUMAN A:[94-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLGSLASVFVRLP--------------CG-GVGVDSDTIWN--EVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPG-HHAEESTPMGFCYFNSVAVAAKL-LQQRLSV--S--KI---LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDG-N--F-FP-GS--GAPD--EVGTGPGVGFNVNMAFTG-G-LDPPMGDAE----YLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
157 PsiBlast_CBE 42.8432% -54 - C2 - - 5G0G ? A:[154-298] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHAQADKMNGFCMFNNLAIAA----RYAQKR--H--RVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDG-S--F-WP-HL--KESDSSSVGSGAGQGYNINLPWNKVG-ME----SGD----YITAFQQLLLPVAYEFQPQLVLVAAGFDAVIG--DPKGGMQVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
106 PsiBlast_CBE 41.7134% -63 - C2 - - 2VQJ A:[94-305] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLGSLASVFVRLP--------------CG-GVGVDSDTIWN--EVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPG-HHAEESTPMGFCYFNSVAVAAKL-LQQRLSV--S--KI---LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDG-N--F-FP-GS--GAPD--EVGTGPGVGFNVNMAFTG-G-LDPPMGDAE----YLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------
141 PsiBlast_CBE 39.3836% -24 - C2 - - 3ZNR HDAC7_HUMAN A:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
138 PsiBlast_CBE 39.0736% -25 - C2 - - 3ZNS HDAC7_HUMAN A:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136 PsiBlast_CBE 38.9136% -27 - C2 - - 3ZNS C:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
142 PsiBlast_CBE 38.8136% -23 - C2 - - 3C10 C:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
145 PsiBlast_CBE 38.2536% -23 - C2 - - 3C0Z C:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137 PsiBlast_CBE 37.3936% -25 - C2 - - 3ZNS HDAC7_HUMAN B:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
144 PsiBlast_CBE 36.9736% -32 - C2 - - 3C10 HDAC7_HUMAN A:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
147 PsiBlast_CBE 36.8636% -30 - C2 - - 3C0Z HDAC7_HUMAN A:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
146 PsiBlast_CBE 36.5536% -24 - C2 - - 3C0Z HDAC7_HUMAN B:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
143 PsiBlast_CBE 36.1436% -23 - C2 - - 3C10 HDAC7_HUMAN B:[189-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHADHSTAMGFCFFNSVAIAC---RQLQQQS--KASKI---LIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDG-N--F-FP-GS--GAVD--EVGAGSGEGFNVNVAWAG-G-LD----PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------