@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : LinJ_07_0770: (2018-03-08 )
MSSGPLRMPTPSAPSTPPPPTATQHHHTSSWRSWGTKGTGQRVAEGGGSTTTGSPNSSAAPPSVSVTVVVLAALTAATVSVAYNSYKVRSRSSRVYRSQSTTPGHSCTRHGEASDPSHTGDIAMDSVKTASPLSPSTARSDATTCCRSTSLGGCGSTAAHTVAGENPSSTAASENELDEGGQRERDVMAQSPSLALHTDTAADAGARSGNRDMRFALCSAPPLQMAHDSTAEFHDRCATPAASAAPSPPPPETPKALLSNYYDLEPYALQGLAGGAHGWKRVFGLLKPEMRRRSGRDEACAEDGGTAADGIPGRRAPGSLTRTYDGSRVTTTDSPALLRESPGAIVPVTPAAATRSPTRRASAVESMYRSSVVKSDVSVHSRVPGQPVATGKPCTARWYGDDHKLFSVAAASSTSASTLAQPLHPPRLSVSPVAGVPSPPSRFLNSFFFPVLQHLSFCVSRSVGSGPGESTTTGEATSGTAGSGVHTASTTNTFATSAALAVAQRNLQRDISTLVATTASVRLGASASSSFPGSHAHTARCSAVSSVAVSPRAGATGSCRSQQQHEGVTAAESCSSFAALHAGRSSSGGQRRKGVSVEGEEGAAQHVLGSHARFLSAEDKQQPGMRGSPRHQSSGACRQTPASSQKSDRSATWSGAGPCKQSIRESAQERRMPPHPSPRAAATAAGATADSGAVPAPPEASSTEEPNAAGTESVGEPASPPTMAHCCTIAEQLAVLTSRREQQHRYTQQLQASRRSAGLGAGAENALPSPLATPSSPAYTGAAAASTTLDVSNAELSKKASGMRSPFAWASQYYTDTASGVFYSSVLQPHHYENHVYSDVTTEVQQCRRRRQRDRVTSLGAGVTPASRAGAEDEDVGHETHTATPMATGAGAATAASTRRSMERPAAESSLTAGLQPAAARKASASAGTAILTSGVGSVAPLSHSKPTQPSNERRVDDLTVKHQDDGSASYTISLTYHDSETGTSRTVNTSALPPLRRCDAGASIPGLSSLSGGTTVRAAARTKRPTTTATLALSASGAASPAHSRSVSGGEAAHAFAVSSPPARPATATMMGKSLLHSQPHQASDAEDNDNASTTLGLAQAARTGGGRPRPAPRSSISVGGSLKYCSSPAAGATAAGSASGSPACDAAAASTTTASGKVNPFAAPLPPTEPQHGPRLRGVAGRNGEMAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAARHHVRWIVGFFGAEKRGHSVLMYLEYCQHGSLLDYMMEGNSTDAAVWNTSSALDDATPKPSTAPADRSAGCHFDANGSPPVAAVAAWRRHTESVNEDASCLSARSPLRGLREVRESHTEAAAAPKTNSPKQQRQQQQVADGGSAAAGHAQRAEAEEAAATGHASPQVRTHREESAEGEEYPERREGDCLSTAAASVSSAASSVALSSSALDMMPLSEALHPQMPSLSIEQAQCFTKQIVEGLCFLHQHNYAHLDVKTANVLVAADDECRLADLGCAMRLQPPPPASPPPQQQGLAGMDKAVRGGANGDLDDAFSPPPYPVLVDRDAITELRGTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIGSARDELPLPPLIRAWAEEAREWLVREGLSATVDAEKQQDDVAACAMEAGGVAQAPRSRSASKKDREVSGVDRDSGVVGGDLDNAVSDTLDEPCSQRRRVDHGTYGCEATATPRSSSALTAKMPASVRTPATSTRGGTTSSSFARAASAMTAGLQLGESNPPDEERFFREQRHVMRLYVALQDFVTACVRVRPEDRSSTAELLRHPFLTLCKDDI

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220--..---.---.-..1230..-....1240.....-.1250......1260----........1270.----.....1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380....--..1390-.......1400......1410......1420......1430......1440......1450......1460----......---...1470......1480......1490......1500.....----.1510---.----.......1520......1530......1540......1550......1560......1570......1580......1590--........1600......1610......1620......1630-......1640........1650..--..----------..1660..-....1670......1680.--.....1690......1700....-..1710......1720----......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840....
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MSSGPLRMPTPSAPSTPPPPTATQHHHTSSWRSWGTKGTGQRVAEGGGSTTTGSPNSSAAPPSVSVTVVVLAALTAATVSVAYNSYKVRSRSSRVYRSQSTTPGHSCTRHGEASDPSHTGDIAMDSVKTASPLSPSTARSDATTCCRSTSLGGCGSTAAHTVAGENPSSTAASENELDEGGQRERDVMAQSPSLALHTDTAADAGARSGNRDMRFALCSAPPLQMAHDSTAEFHDRCATPAASAAPSPPPPETPKALLSNYYDLEPYALQGLAGGAHGWKRVFGLLKPEMRRRSGRDEACAEDGGTAADGIPGRRAPGSLTRTYDGSRVTTTDSPALLRESPGAIVPVTPAAATRSPTRRASAVESMYRSSVVKSDVSVHSRVPGQPVATGKPCTARWYGDDHKLFSVAAASSTSASTLAQPLHPPRLSVSPVAGVPSPPSRFLNSFFFPVLQHLSFCVSRSVGSGPGESTTTGEATSGTAGSGVHTASTTNTFATSAALAVAQRNLQRDISTLVATTASVRLGASASSSFPGSHAHTARCSAVSSVAVSPRAGATGSCRSQQQHEGVTAAESCSSFAALHAGRSSSGGQRRKGVSVEGEEGAAQHVLGSHARFLSAEDKQQPGMRGSPRHQSSGACRQTPASSQKSDRSATWSGAGPCKQSIRESAQERRMPPHPSPRAAATAAGATADSGAVPAPPEASSTEEPNAAGTESVGEPASPPTMAHCCTIAEQLAVLTSRREQQHRYTQQLQASRRSAGLGAGAENALPSPLATPSSPAYTGAAAASTTLDVSNAELSKKASGMRSPFAWASQYYTDTASGVFYSSVLQPHHYENHVYSDVTTEVQQCRRRRQRDRVTSLGAGVTPASRAGAEDEDVGHETHTATPMATGAGAATAASTRRSMERPAAESSLTAGLQPAAARKASASAGTAILTSGVGSVAPLSHSKPTQPSNERRVDDLTVKHQDDGSASYTISLTYHDSETGTSRTVNTSALPPLRRCDAGASIPGLSSLSGGTTVRAAARTKRPTTTATLALSASGAASPAHSRSVSGGEAAHAFAVSSPPARPATATMMGKSLLHSQPHQASDAEDNDNASTTLGLAQAARTGGGRPRPAPRSSISVGGSLKYCSSPAAGATAAGSASGSPACDAAAASTTTASGKVNPFAAPLPPTEPQHGPRLRGVAGRNGEMAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDA--KD---R---K-LRTRLKQL-ELELEVLTLAARH-HVRWIVGFFGAEK------RGHSVLMYLEYCQ----HGSLLDYMMEGNSTDAAVWNTSSALDDATPKPSTAPADRSAGCHFDANGSPPVAAVAAWRRHTESVNEDASCLSARSPLRGLREVRESHTEAAAAPKTNSPKQQRQQQQVADG--GSAAA--GHAQRAEAEEAAATGHASPQVRTHREESAEGEEYPERREGDCLSTAAASVSSAASSVALSSSALDMMP-------LSEALH---PQMPSLSIEQAQCFTKQIVEGLCFLHQHNYAHLDVKTANVLV----AA--D---D----ECRLADLGCAMRLQPPPPASPPPQQQGLAGMDKAVRGGANGDLDDAFSPPPYPVLVDRDAITELRGTALYMAPEMIRFE----SHAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIG-SARDELP--LPPLIRAWAEEAREW--LV----------REGLSATV-DAEKQQDDVAACAMEAGGV--AQAPRSRSASKKDREVSGVDRDS-GVVGGDLDNAVSDTLD----EPCSQRRRVDHGTYGCEATATPRSSSALTAKMPASVRTPATSTRGGTTSSSFARAASAMTAGLQLGESNPPDEERFFREQRHVMRLYVALQDFVTACVRVRPEDRSSTAELLRHPFLTLCKDDI
47 Fugue 71.9320% 4 - C1 - - 4AW2 MRCKA_RAT A:[1-416] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECN--NSPLR--REKNILEYLEWAKPFTSKVKQMRLHREDFEI--LKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLS---KFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM----DM--N---G----HIRLADFGSCLKLME----------------DGTVQSSVA------------------------VGTPDYISPEILQAMEGG-KGRYGPECDWWSLGVCMYEMLYGETPFY--AESLVETYGKIM-NHKERFQ--FPTQVTDVSENAKDL--IR----------RLICSREHRLGQNGIEDFKKHPFFSGID--WDNIRNCEAPYIPEVSSPTDTSNFDVDSGHHLPFVGFTYT----SSCVLSDRSCLR----------------------------------------------------------------------------------------------------------------
44 Fugue 65.3821% -15 - C1 - - 4DN5 M3K14_HUMAN A:[8-351] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVEEYLVHALQGSVSSGQAHSLTSLAKTWAARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQ-LRL--GRGSF--GEVHRMEDKQTG-FQCAVKKVRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMEL--LEGGS-------LGQLVK---EQ-GCLPEDRALYYLGQALEGLEYLHSRRILHGDVKADNVLL----SS--DG--S----HAALCDFGHAVCLQIP-------------------------------------------------GTETHMAPEVVLGR----SC--DAKVDVWSSCCMMLHMLNGCHPWTQF--FRGPLCLKIASEPPPVRE--IPPSCAPLTAQAIQE--GL----------RKEPIHRV-SAAELGGKVNRALQQVGGL--KSPWRGEYKEPRHP----------------------------------------------------------------------------------------------------------------------------------------------------------
25 HHSearch 64.4826%-103 - C1 - - 2WEL KCC2D_HUMAN A:[3-213] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKK--LS----------ARDHQKL-EREARICRL---L-KHPNIVRLHDSIS------EEGFHYLVFDLVT----GGELFEDIVARE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL----AS--KSKGA----AVKLADFGLAIEVQGDQ-----------------------------------------QAWFGFAGTPGYLSPEVLRK------DPYGKPVDMWACGVILYILLVGYPPFWDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 HHSearch 63.6425% -40 - C1 - - 2Y7J PHKG2_HUMAN D:[93-308] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEV-----RLSPE---Q-LEEVREAT-RRETHILRQ---VAGHPHIITLIDSYE------SSSFMFLVFDLMR----KGELFDYLTEKV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DD--N---M----QIRLSDFGFSCHLEPGE------------------------------------------KLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46 Fugue 62.3618% 44 - C1 - - 3C4Z RK_BOVIN A:[31-533] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD---R---K-YLARLKLPPLSKCEALRESLDL-GFEGMC-----LE------QPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGGLFQPLLRAVLAHLG-QAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFA--CQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGD-------IRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLL----DD--D---G----NVRISDLGLAVELKAGQTKTKGYA-----------------------------------------GTPGFMAPELLLGE----EY--DFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQR-VLEQAVT--YPDKFSPASKDFCEA--LLQKDPEKRLGFRDGSCDGL-RTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNGAFSGVAFE-------KADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP------------------------------------------------------------------------------------------------------
35 HHSearch 62.1026% -71 - C1 - - 2X0G - DAPK1_HUMAN A:[10-220] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRR--TK---S---SRRGVSREDI-EREVSILKE---I-QHPNVITLHEVYE------NKTDVILILELVA----GGELFDFLAEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML----LD--R---NVPKPRIKIIDFGLAHKIDFGN------------------------------------------EFKNIFGTPEFVAPEIVNY------EPLGLEADMWSIGVITYILLSGASPFLGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 HHSearch 60.5728%-109 - C1 - - 5IU2 M3K8_HUMAN B:[72-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TYRN-GSDFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQ-------------------FK-PSDVEIQAC---F-RHENIAELYGAVL------WGETVHLFMEAGE----GGSVLEKLESCG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVF----MS--T--------KAVLVDFGLSVQMTEDV-----------------------------------------YFPKDLRGTEIYMSPEVILC------RGHSTKADIYSLGATLIHMQTGTPPWVKR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 HHSearch 60.5325% -43 - C1 - - 2Y7J PHKG2_HUMAN C:[93-308] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTA--ER---LSPEQ-LEEVREAT-RRETHILRQ---VAGHPHIITLIDSYE------SSSFMFLVFDLMR----KGELFDYLTEKV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DD--N---M----QIRLSDFGFSCHLEPGE------------------------------------------KLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 HHSearch 60.1525%-122 * C1 * - 3C0I CSKP_HUMAN A:[23-235] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAK--FT---S---S-PGLSTEDL-KREASICHM---L-KHPHIVELLETYS------SDGMLYMVFEFMD----GADLCFEIVKRADA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL----AS--K---ENSA-PVKLGGFGVAIQLGESG-----------------------------------------LVAGGRVGTPHFMAPEVVKR------EPYGKPVDVWGCGVILFILLSGCLPFYG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 HHSearch 58.8825%-128 - C1 - - 3C0G CSKP_HUMAN B:[23-235] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAK--FT---S---S-PGLSTEDL-KREASICHM---L-KHPHIVELLETYS------SDGMLYMVFEFMD----GADLCFEIVKRADA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL----AS--K---ENSA-PVKLGGFGVAIQLGESG-----------------------------------------LVAGGRVGTPHFMAPEVVKR------EPYGKPVDVWGCGVILFILLSGCLPFYG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 HHSearch 58.7624%-130 - C1 - - 4XBR INKA1_HUMAN A:[94-293] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRK--Q------------QRRELL-FNEVVIMRD---Y-QHENVVEMYNSYL------VGDELWVVMEFLE----GGALTDIVTHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILL----TH--D---G----RVKLSDFGFCAQVSKEV-----------------------------------------PRRKSLVGTPYWMAPELISR------LPYGPEVDIWSLGIMVIEMVDGEPPYFNE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 HHSearch 58.7027%-131 - C1 - - 2X4F MYLK4_HUMAN A:[89-291] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YTVSKTEILG-----QVHKCEETATGLKLAAKIIKTRG--M------------KDKEEV-KNEISVMNQ---L-DHANLIQLYDAFE------SKNDIVLVMEYVD----GGELFDRIIDES-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVN--RD--A---K----QIKIIDFGLARRYKPRE------------------------------------------KLKVNFGTPEFLAPEVVNY------DFVSFPTDMWSVGVIAYMLLSGLSPFLGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 HHSearch 57.7527% -40 - C1 - - 5BYZ MK07_HUMAN A:[5-218] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAF--DV----------VTNAKRT-LRELKILKH---F-KHDNIIAIKDILRPTVPYGEFKSVYVVLDLME----S-DLHQIIHSSQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLV----NE--N---C----ELKIGDFGMARGLCTSPAE-------------------------------------HQYFMTEYVATRWYRAPELMLSL-----HEYTQAIDLWSVGCIFGEMLARRQLFPGK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 HHSearch 57.2523%-112 - C1 - - 1TKI - TITIN_HUMAN A:[21-223] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKG---------------TDQVLV-KKEISILNI---A-RHRNILHLHESFE------SMEELVMIFEFIS----GLDIFERINTSA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIY----QTRRS---S----TIKIIEFGQARQLKPGD------------------------------------------NFRLLFTAPEYYAPEVHQH------DVVSTATDMWSLGTLVYVLLSGINPFLAE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 HHSearch 55.8624%-128 - C1 - - 4BGQ CDKL5_HUMAN A:[11-215] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFK-------------------VKETT-LRELKMLRT---L-KQENIVELKEAFR------RRGKLYLVFEYVE----KNMLELLEEMPN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLI----SH--N---D----VLKLCDFGFARNLSE---------------------------------------------------TRWYRSPELLLG------APYGKSVDMWSVGCILGELSDGQPLFPGE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 53.0725%-117 - C1 - - 5J5T M4K3_HUMAN A:[2-209] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEP--G------------EDFAVV-QQEIIMMKD---C-KHPNIVAYFGSYL------RRDKLWICMEFCG----GGSLQDIYHVTG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILL----TD--N---G----HVKLADFGVSAQITATI-----------------------------------------A---AFIGTPYWMAPEVAAVER---KGGYNQLCDLWAVGITAIELAELQPPMFDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48 Fugue 51.4013% 31 - C1 - - 4BTF MLKL_MOUSE A:[7-460] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKLGQIIKLGQLIYEQCEKM---K---Y-CRKQCQRL-GNRVHGLLQPLQR-LQAQGKKNLPDDI------TAALGRFDEVLKE----ANQQIEKFILFHEVNEKLRDVWEELLLLLQVPASWQQEDRQDAEEDGN-ENMKVILMQLQISVEEINKTLKQCSIPQD-LQIKEIPKEHLGPPWTKLKTSKMSTIYRGEYHRS--PVTIK--VFNNPQAESVGIVRFTFNDEIKTMKKFD---SPNILRIFGICIDQ-----TVKPPEFSIVMEYCELGT-------LRELLD---RE-KDLTMSVRSLLVLRAARGLYRLHHSETLHRNISSSSFLV----AG--G---Y----QVKLAG---------------------------------------------FELSKTQNSISRTASSTIYVSPERLKNP----FCLYDIKAEIYSFGIVLWEIATGKIPFEGCDSKKIRELVAED-KKQEPVGQDCPELLREIINECRAHEPSQ----------RPSVDGIL-ERLSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 HHSearch 50.3423%-103 - C1 - - 4NIF - KS6A1_HUMAN A:[7-209] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK------------------RDP-SEEIEILLR--YG-QHPNIITLKDVYD------DGKHVYLVTELMR----GGELLDKILRQK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILY----VD--E---SGNPECLRICDFGFAKQLRAEN-----------------------------------------GLLMTPCY---FVAPEVLKR------QGYDEGCDIWSLGILLYTMLAGYTPFANG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 50.2725%-144 - C- - - 5CEN - M3K12_HUMAN A:[204-332] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGR---PVTPSLLVD----WSMGIAGGMNYLHLHKIIHRDLKSPNMLI----TY--D---D----VVKISDFGTSKELS------------------------------------------DKSTKMSFAGTVAWMAPEVIRNE----P--VSEKVDIWSFGVVLWELLTGEIPYKDV--DSSAIIWGVG-SNSLHLP--VP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 HHSearch 49.0424% 0 - C- - - 5JZN DCLK1_HUMAN A:[18-223] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSK--CR-----------GKEHMI-QNEVSILRR---V-KHPNIVLLIEEMD------VPTELYLVMELVK----GGDLFDAITSTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDG--S---K----SLKLGDFGLATIVDGP--------------------------------------------LYTVCGTPTYVAPEIIAE------TGYGLKVDIWAAGVITYILLCGFPPFRGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------