@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LinJ_33_1490: (2018-03-12 )
MLSCTSNLSSDAAAASEPPPSPRPRTPGPPIVASASHSSMPSMAATQIVSRGGSPTPPLTTDVDIRGPFLLYGPSGRLLSRYEPSDLWGLLISEHTTLNCTYAQTTVRVGRAGGCDTVLSDPRVSSTHFTISLELEPYGNSDHRNHWRGSGVGGGDHEIPLLLRRSPEGSPVHTRGMHTNASDAIASGAGVPKSAASGGLTSSSSLCSVAAAEKGLNKDGRSDARALSETTLPGWRVSRVSLTDCSANGTYVNDVLVGRGKCCDLHYGDDISIVRVPEKKRPRRGSTTPTDLSSEEDETQQESENEVACFAQSERGAELRRGTVAAPSSSAHHVAPSSRDALAGGGAARMGTEANEEGSSPSGDDPRVTQMFTALLSTLSTEHTYVERFCFHLYHAEEVGRGGAPIIEPDTVVASQRAAAGEVEAEAERQREDNDEQDKYNDVLQQSQPELKHNLSQHKSVRFPDDPVTAFDPPPQNADSDAVDSPPASLSALQHRDRRASLSMSPIPPCALVPGDTSASAAFAPQSSANSLTLSTVVTPHSLLRPRPSIRESFIAPISLPDPEESTAPSNGSVHGSVMASTSVIRFHESIGISAALRRKAAAQRALAARRGSSTASNQANGSLGTVGAIMKDMPPDIPIRYAVLPLRHLQWGGRIGFGASGDVFMGIDVSTATVVAIKVLKGSSLFQSSQPADTTVAKAHSKTTSGRSAVPSVQDDGTILNLSNISLGNGTVTDHRASSEGWTCAPPSLASPMTVPSHRATSRQVDHTNEESIQVSEASTPLTPASAVTSSSASAHGNTSAALVNTSSTSHCHTQVQQQQQPPRPQSQDEHSAAPLLRKHLREIIFLTTLQHHRIVRFLGFQFSGEGRLCLLMEYVAGGTLQTLVKNFGVFEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQGSVKLTDFGTSRFLRACAAEEKGAGEAAGADDERPGAEVRRARRRGESREVHHAPADRARKRYHHGNSPGADAAVSEDGRGEDISVGNSEGCGECCRGGSDEDVYPDDVHSAEDNFEEDEEGEEPNEDDGSERRLLCGTPLYMSPELIRTQEPTFASDMWALGCVVYEMATGGVLPWRPVHNLSAPAVIWYIGQRGEEGDGPSMDDVYTERDRLNRASTDPSLHEAVDDSYDEEGGGHRGHSSRGGRVGRWDRTPSPMLLDLLQSTLNMNPALRPTPAELLQHPFIRNEASNAALERWHALVAANRLPATHALKQHGEEGEELMSHRTLKAEPVADIKSTLRSVRGSASRDGSQHARASLSPARTPPSPQAIEVEELDDNAPAKLGGENPPGTASRQQHPSRHPPPPLGEPMTSPSMNLLGDPCEDAEPSSVLPLPPPASQPKPQMPKAHAVQVPSVLGAGSPDSQPLICEPPRRPDIRGRRMDAPPPVISQAAASPERFPSASHGAASLPWWTPQSFSAPTKLPVSRSRASASALVGMRQVEQQAPYTMPVTQQSTSKSYLRQHQLFLKQNELERRRISFLVPQGGRQMSGRHRTEGPPILQQQQQQPLPMASAPAAAGIMPMCPPSYQYAMQQPVLEYTPGYSDYNPQVNTQTVEMRLPPGFTSQSLSAPHQQGRRQSWSIGSNRVLAGVQLQSVASSQKPLSQQLRGNKPKHSSRRERARIAPTTAAASNVSPSLHTSTRSPVISMNSSHVRGPAAADSTRESSGPVLSHTSQQFAPQQQLSMQQLHPVVGGLTMEMDNLTISSPLLSSFAASMAPLPVQDHRCVLSYSGAPMPVDQPVSKSPQAHCQGPVLALLSHPRHRHTAHAQSATTSSLGPGSGDGGGAVQQASPANAAEVEGAGNSAAQRNARRGRQGRRSALSSSSLLLHQNRLRNPRRASPLLRQQLHQMTLTSTRTCVVEHSDKQEQQQIPSLNEEAPASQQQEEPRSTKRPCAARSNGRSSSTYTAGKKRRIRTSLRVSTREAIRRQQQRRSQKQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620......-.630.......640.......650.......660.......670.......680.......690.......700.-......710.......720.......730.......740.......750.......760.......770.......780.......790....---...800.......810.......820.......830.......840.......850........860...---....870.......880........890--.----........900.......910.-..--....920.......---930-.---.----.--......940.......950.......960.......970.......980.......990.......1000........1010......-------1020......--------------1030......1040......1050......1060......1070......1080---..-......--.1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200...-----...1210......1220......1230......1240......1250.....---.1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MLSCTSNLSSDAAAASEPPPSPRPRTPGP
P
I
V
ASASHSSM
P
S
M
A
A
T
Q
I
V
SRGGSPTPPLTT
D
V
DIRG
P
F
L
L
YGPSG
R
L
L
S
RY
E
P
S
D
L
W
G
L
L
ISEH
T
T
L
N
C
T
Y
A
Q
T
T
V
R
VGRAGGCDTVLSDPRVSS
T
H
F
T
I
S
L
E
L
E
PYGNSDHRNHWRGSGVGGGDHE
I
P
L
L
L
R
RSPEGSP
V
H
TRGMHTNA
S
D
AIASGAGVPKSAASGGLTSS
S
S
L
C
S
V
A
A
A
EKGLNKDGR
S
D
A
R
A
L
SETTLPG
W
R
V
S
R
V
S
L
TDCSANG
T
Y
V
N
D
V
LVGRG
K
C
C
DLHYGDD
I
S
I
V
RVPEKKRPRRGSTTPTDLSSEEDETQQESEN
E
V
A
C
F
AQSERGAELRRGTVAAPSSSAHHVAPSSRDALAGGGAARMGTEANEEGSSPSGDD
P
R
V
T
Q
M
F
T
A
L
L
S
T
LST
E
H
T
Y
V
E
R
F
C
F
H
L
Y
H
A
E
E
VGRGGAPIIEPDT
V
V
ASQRAAAGE
V
E
A
E
A
E
RQREDND
E
Q
D
K
Y
N
D
V
L
Q
QS
Q
P
E
L
K
H
N
L
S
QHKSVRFPDDPVTAFDPPPQNADSDAVDSPP
A
S
L
S
A
L
Q
H
R
D
R
RASLSMSPIPP
C
A
LVPGDTSASAAFAPQSSAN
S
L
T
L
S
T
VVT
P
H
S
LLRPR
P
S
I
R
E
SFIAPISLPDPEESTAPSNGSV
H
G
S
V
M
A
S
T
S
V
I
R
F
H
E
SI
G
I
S
A
A
L
R
R
K
A
A
A
Q
R
A
L
A
ARRGSSTASNQANGSL
G
T
V
G
-
A
I
M
KDMPPDI
P
I
R
Y
A
VL
P
L
RHLQWGGRIGFGASG
D
V
F
M
G
I
DVS
T
A
T
V
V
A
I
K
V
LKGSSLFQSSQPADTT
V
A
KAHSK-TTSGRSAVPSVQDD
G
T
I
L
N
L
S
N
I
SLGN
G
T
VTDHRASSEGWTCAPPSLASPMTVPSHRATSRQVDHTNEE
S
I
Q
VSEASTPLTP
A
S
AVTSSSASA---HGNT
S
A
A
L
V
NTSST
S
H
C
H
T
Q
V
Q
Q
QQQPPRPQSQDE
H
S
A
A
P
L
L
R
K
H
L
R
E
I
I
F
L
T
T
L
-
Q
H
H
R
I
V
R
F
L
G
F
Q
FS---GE
G
R
L
C
L
L
M
E
Y
VAG
G
-
T
L
Q
T
L
V
K
NFG----
V
----
F
E
E
N
V
I
R
L
Y
T
L
Q
I
L
E
G
L
E
Y
L
K
R-KG--VVHGDLKS
A
N
I
L
V
S---E---Q---G----
S
--
V
K
L
TDF
G
T
S
R
F
L
R
A
C
AAEEKGAGEAAGADDERP
G
A
E
V
R
R
A
R
RRGESREVHHA
P
A
D
R
A
R
K
R
YHHGNSP--GADAAVSEDGRGEDISVGN-------SEG
C
G
E
C
CRG--------------GSDEDVYPDDVHSAEDNFEEDEEGEEPNEDDGSE
R
R
L
L
CGTPLYMSP
E
L
IR------TQ-EPT
F
A
S
--
D
M
W
A
L
G
C
V
V
Y
E
MATGGVLPWRPVHNLSA
P
A
V
I
W
Y
IGQRGEEGDGPS
M
D
D
V
Y
T
E
R
D
RLNRASTDP
S
L
H
E
AVDDSYDEEGGGHRGHSSRGGRVGRWDRTP
S
P
M
L
L
D
L
L
Q
S
T
LNMNPALRP-----
T
P
A
E
L
L
QHPFIRNEAS
N
A
A
L
E
R
W
H
A
L
V
A
ANRL
P
A
T
H
A
L
K
QHGE
E
G
E
E
L
M
S
HR---TLKAE
P
V
A
D
I
K
S
T
L
R
S
V
RGSASRDGS
Q
H
A
RASLSPARTPPSPQ
A
I
E
V
EELDDNAPAKLGGENPPGTASRQQHPSRHPPPPLGEPMTSPSMNLLGDPCEDAEPSSVLPLPPPASQPKPQMPKAHAVQVP
S
V
LGAGSPDSQPLICEPPRRPDIRGRRMDAPP
P
V
I
S
Q
AAASPERFPSASHGAASLPWWTPQSFSAPTKLPVSRSRA
S
A
S
A
L
V
G
M
R
Q
V
E
QQAPYTMPVTQQS
T
S
K
S
Y
L
R
Q
H
Q
L
F
L
K
Q
N
E
L
E
R
R
R
I
S
F
L
VPQGGRQMSGRHRTEGPP
I
L
Q
Q
QQQQPLPMASAPAAAGIMPMCPP
S
Y
Q
Y
A
M
QQ
P
V
L
EYTPGYSDYNPQVN
T
Q
T
V
E
M
RLPPGFTSQSLSA
P
H
Q
QGRRQSWSIGSN
R
V
L
A
G
V
Q
L
Q
S
V
ASSQK
P
L
S
Q
Q
LRGNKPKH
S
S
R
R
E
RARIAPTTAAASNVSPSLHTSTRS
P
V
I
SMNSSHVRGPAAADSTRESSGPVLSHT
S
Q
QFA
P
Q
Q
Q
L
S
M
Q
Q
L
H
P
V
VG
G
L
T
M
E
MDN
L
T
IS
S
P
L
L
S
S
F
A
A
SMAPLPVQD
H
R
C
V
L
SYSGAPMPVDQPVSKSPQAHCQG
P
V
L
A
L
LSHPRHRHTAHAQSATTSSLGPGSGDGGGAVQQASPANA
A
E
VEGAGN
S
A
A
Q
R
N
A
R
RGRQ
G
R
R
SALSS
S
S
L
L
L
H
Q
N
RLRNPRR
A
S
P
L
L
R
Q
Q
L
H
Q
M
TLTST
R
T
C
V
VEHS
D
K
Q
E
Q
Q
QIPSLNEEAPAS
Q
Q
Q
EEPRSTKRPCAARSNGRSSSTYTAGKK
R
R
I
R
T
S
LR
V
S
T
R
E
A
I
R
R
Q
Q
Q
R
RSQKQ
38
HHSearch
70.04
33%
-123
* C1 *
-
4XBR
1
INKA1_HUMAN (first)
A:
[138-351]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
N
E
V
V
I
M
R
D
Y
-
Q
H
E
N
V
V
E
M
Y
N
S
Y
L
V
----
G
D
E
L
W
V
V
M
E
F
L
E
G
G
-
A
L
T
D
I
V
T
H
T
-----
R
----
M
N
E
E
Q
I
A
A
V
C
L
A
V
L
Q
A
L
S
V
L
H
A
-
Q
G
--
V
I
H
R
D
I
K
S
D
S
I
L
L
T
---
H
---
D
---
G
----
R
--
V
K
L
S
D
F
G
F
C
A
Q
V
S
K
E
V
---------------------------------------------------------------------------------------------------------------------------------------
P
R
R
K
S
L
V
G
T
P
Y
W
M
A
P
E
L
I
S
------
R
L
-
P
Y
G
P
E
V
--
D
I
W
S
L
G
I
M
V
I
E
M
V
D
-
G
E
P
P
Y
F
N
E
P
P
L
K
---
A
M
K
M
I
R
D
N
-----
L
P
P
----------------
R
---------------------------
L
K
N
-
L
H
K
V
S
P
S
L
K
G
F
L
D
R
L
L
V
R
D
P
A
Q
R
A
-----
T
A
A
E
L
L
K
H
P
F
L
A
K
A
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
68.02
17%
30
- C1 -
-
2ACX
1
GRK6_HUMAN
A:
[14-532]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
R
K
G
K
S
K
K
W
R
Q
M
L
Q
F
P
H
I
S
Q
C
E
E
L
R
L
S
L
E
-----
R
D
Y
H
S
L
C
E
R
N
P
I
G
R
L
L
F
R
E
F
C
A
T
R
P
E
L
S
R
C
V
A
F
L
D
G
V
A
E
Y
E
V
T
P
D
D
K
R
K
A
C
G
R
N
L
T
Q
N
F
L
S
H
T
G
P
D
L
I
P
E
V
P
R
Q
L
V
T
N
C
T
Q
R
L
E
Q
G
P
C
K
D
L
F
Q
E
L
T
R
L
T
H
E
Y
L
S
V
A
P
F
A
D
Y
L
D
S
I
Y
F
N
R
F
L
Q
W
K
W
L
E
R
Q
P
V
T
K
N
T
-------
F
R
Q
Y
R
V
L
G
K
G
G
---
F
G
E
V
C
A
C
Q
V
R
A
T
G
K
M
Y
A
C
K
K
L
E
K
K
R
I
K
K
R
K
G
E
A
M
A
L
N
E
K
Q
I
L
E
K
------------
V
N
S
R
F
V
V
S
L
A
Y
A
Y
E
---
T
K
D
A
L
C
L
V
L
T
L
M
N
G
G
-
D
L
K
F
H
I
Y
H
M
G
Q
A
--
G
----
F
P
E
A
R
A
V
F
Y
A
A
E
I
C
C
G
L
E
D
L
H
R
-
E
R
--
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
---
D
---
H
---
G
----
H
--
I
R
I
S
D
L
G
L
A
V
H
V
P
----------------------------------------------------------------------------------------------------------------------------------------
E
G
Q
T
I
K
G
R
V
G
T
V
G
Y
M
A
P
E
V
V
K
------
N
E
-
R
Y
T
F
S
P
--
D
W
W
A
L
G
C
L
L
Y
E
M
I
A
G
Q
-
S
P
F
Q
Q
R
K
K
K
I
K
R
E
E
V
E
R
L
V
K
E
V
P
E
E
Y
S
E
R
F
S
------------
P
Q
A
R
S
L
C
S
Q
L
L
C
K
D
P
A
E
R
L
G
C
R
G
G
S
A
R
E
V
K
E
H
P
L
F
K
K
L
N
F
K
R
L
G
A
G
M
L
E
P
P
F
K
P
D
P
Q
A
-----
I
Y
C
E
P
T
D
Q
D
F
Y
Q
K
F
A
T
G
S
V
P
I
P
W
Q
N
E
M
V
E
T
--
E
C
F
Q
E
L
N
V
F
G
L
D
G
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
64.35
29%
-111
- C1 -
-
4Y85
1
M3K8_HUMAN
B:
[115-327]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
E
I
Q
A
C
F
-
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
----
G
E
T
V
H
L
F
M
E
A
G
E
G
G
-
S
V
L
E
K
L
E
S
C
G
----
P
----
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
-
K
K
--
V
I
H
H
D
I
K
P
S
N
I
V
F
M
---
S
---
T
--------
K
--
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
---------------------------------------------------------------------------------------------------------------------------------------
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
------
C
R
-
G
H
S
T
K
A
--
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
-
G
T
P
P
W
V
K
R
Y
P
R
S
A
Y
P
S
Y
L
Y
I
I
H
K
---------------------
Q
--
A
-------------------------
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
-----
R
A
A
D
L
L
K
H
E
A
L
N
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
63.60
31%
-88
- C1 -
-
5IG1
-
?
A:
[62-280]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
K
R
E
I
G
I
C
S
S
L
-
Q
H
E
H
I
V
S
M
R
R
A
F
R
D
----
E
S
H
F
Y
L
V
F
E
Y
V
S
G
G
-
E
L
F
D
E
I
V
T
R
K
----
F
----
Y
N
E
K
D
A
S
A
C
M
H
Q
I
L
S
A
L
Q
H
C
H
S
-
K
N
--
I
I
H
R
D
L
K
P
E
N
L
L
L
A
SKD
P
---
N
---
A
----
P
--
V
K
I
T
D
F
G
L
A
V
I
M
E
Q
G
----------------------------------------------------------------------------------------------------------------------------------------
P
T
Y
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
I
R
------
R
V
-
P
Y
D
T
A
V
--
D
V
W
A
C
G
V
I
L
Y
I
L
L
V
-
G
Y
P
P
F
W
E
E
D
H
Q
K
---
L
Y
A
Q
I
K
N
C
Q
--
Y
D
F
-----------------
P
-----------------------------
S
P
E
W
D
S
V
T
T
A
A
K
E
L
I
K
A
M
L
E
P
N
P
K
R
R
P
-----
T
V
Q
E
L
L
Q
H
P
W
I
A
R
R
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
62.32
30%
-85
- C1 -
-
3I6U
-
CHK2_HUMAN
A:
[268-493]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
V
E
T
E
I
E
I
L
K
K
L
-
N
H
P
C
I
I
K
I
K
N
F
F
D
A
-----
E
D
Y
Y
I
V
L
E
L
M
E
G
G
-
E
L
F
D
K
V
V
G
N
K
----
R
----
L
K
E
A
T
C
K
L
Y
F
Y
Q
M
L
L
A
V
Q
Y
L
H
E
-
N
G
--
I
I
H
R
D
L
K
P
E
N
V
L
L
S
---
S
QEE
D
---
C
----
L
--
I
K
I
T
D
F
G
H
S
K
I
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------
P
T
Y
L
A
P
E
V
L
V
-------
A
-
G
Y
N
R
A
V
--
D
C
W
S
L
G
V
I
L
F
I
C
L
S
-
G
Y
P
P
F
S
E
H
R
T
Q
V
S
--
L
K
D
Q
I
T
S
G
K
----
Y
N
--------------------------------------------
F
I
P
E
V
W
A
E
V
S
E
K
A
L
D
L
V
K
K
L
L
V
V
D
P
K
A
R
F
-----
T
T
E
E
A
L
R
H
P
W
L
Q
D
E
D
M
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
62.04
32%
-78
- C1 -
-
5J5T
1
M4K3_HUMAN
A:
[48-269]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
Q
E
I
I
M
M
K
D
C
-
K
H
P
N
I
V
A
Y
F
G
S
Y
L
R
----
R
D
K
L
W
I
C
M
E
F
C
G
G
G
-
S
L
Q
D
I
Y
H
V
T
G
----
P
----
L
S
E
L
Q
I
A
Y
V
S
R
E
T
L
Q
G
L
Y
Y
L
H
S
-
K
G
--
K
M
H
R
D
I
K
G
A
N
I
L
L
T
---
D
---
N
---
G
----
H
--
V
K
L
A
D
F
G
V
S
A
Q
I
T
A
T
I
---------------------------------------------------------------------------------------------------------------------------------------
A
---
A
F
I
G
T
P
Y
W
M
A
P
E
V
A
A
V
ER---
K
G
-
G
Y
N
Q
L
C
--
D
L
W
A
V
G
I
T
A
I
E
L
A
E
L
-
Q
P
P
M
F
D
L
H
P
M
R
---
A
L
F
L
M
T
K
S
N
-----------------
F
----
Q
P
P
-------------------------
K
L
-
K
D
K
M
K
W
S
N
S
F
H
H
F
V
K
M
A
L
T
K
N
P
K
K
R
P
-----
T
A
E
K
L
L
Q
H
P
F
V
T
Q
H
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
61.55
32%
-54
- C1 -
-
4GV1
4
AKT1_HUMAN
A:
[54-276]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
T
L
T
E
N
R
V
L
Q
N
S
-
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
----
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
-
E
L
F
F
H
L
S
R
E
R
----
V
----
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
--
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
---
K
---
D
---
G
----
H
--
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
---------------------------------------------------------------------------------------------------------------------------------------
A
T
M
K
T
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
------
D
N
-
D
Y
G
R
A
V
--
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
-
G
R
L
P
F
Y
N
Q
D
H
E
K
---
L
F
E
L
I
L
M
E
------------------------
E
----------------------------
I
R
F
P
R
T
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
GGGS
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
60.85
28%
-104
- C1 -
-
5IU2
1
M3K8_HUMAN
B:
[115-326]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
E
I
Q
A
C
F
-
R
H
E
N
I
A
E
L
Y
G
A
V
L
W
----
G
E
T
V
H
L
F
M
E
A
G
E
G
G
-
S
V
L
E
K
L
E
S
C
G
----
P
----
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
-
K
K
--
V
I
H
H
D
I
K
P
S
N
I
V
F
M
---
S
---
T
--------
K
--
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
---------------------------------------------------------------------------------------------------------------------------------------
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
------
C
R
-
G
H
S
T
K
A
--
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
-
G
T
P
P
W
V
K
R
Y
P
R
S
A
---
Y
P
S
Y
L
Y
I
------------------
I
H
K
Q
--
A
-------------------------
P
P
L
E
D
I
A
D
D
C
S
P
G
M
R
E
L
I
E
A
S
L
E
R
N
P
N
H
R
P
-----
R
A
A
D
L
L
K
H
E
A
L
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
59.65
34%
0
- C- -
-
4PDP
-
?
B:
[240-472]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
T
R
E
L
E
V
L
Q
K
L
-
N
H
P
R
I
V
R
L
K
G
F
Y
E
D
------
S
Y
Y
M
V
M
E
F
V
S
G
G
-
D
L
M
D
F
V
A
A
H
G
----
A
----
V
G
E
D
A
G
R
E
I
S
R
Q
I
L
T
A
I
K
Y
I
H
S
-
M
G
--
I
S
H
R
D
L
K
P
D
N
I
L
I
E
---
Q
---
D
---
D
----
P
V
L
V
K
I
T
A
F
G
L
A
K
V
Q
---------------------------------------------------------------------------------------------------------------------------------------------------
T
L
A
Y
V
A
P
E
V
I
---------N
E
Y
S
S
L
V
--
D
M
W
S
M
G
C
L
V
Y
V
I
L
T
-
G
H
L
P
F
S
G
S
T
Q
D
Q
---
L
Y
K
Q
I
G
R
G
S
----
Y
H
----------------
E
G
--------------------------
P
--
L
K
D
F
R
I
S
E
E
A
R
D
F
I
D
S
L
L
Q
V
D
P
N
N
R
S
-----
T
A
A
K
A
L
N
H
P
W
I
K
M
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
57.49
24%
-62
- C1 -
-
4B4L
2
DAPK1_HUMAN
A:
[61-282]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
I
E
R
E
V
S
I
L
K
E
I
-
Q
H
P
N
V
I
T
L
H
E
V
Y
E
N
----
K
T
D
V
I
L
I
L
E
L
V
A
G
G
-
E
L
F
D
F
L
A
E
K
E
----
S
----
L
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
-
L
Q
--
I
A
H
F
D
L
K
P
E
N
I
M
L
L
---
D
---
R
---
N
VP
K
P
R
--
I
K
I
I
D
F
G
L
A
H
K
I
D
F
G
N
----------------------------------------------------------------------------------------------------------------------------------------
E
F
K
N
I
F
G
T
P
E
F
V
A
P
E
I
V
N
------
Y
E
-
P
L
G
L
E
A
--
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
-
G
A
S
P
F
L
G
D
T
K
Q
E
---
T
L
A
N
V
S
A
V
N
-------------------
Y
E
-------------
F
----------------
E
D
E
Y
F
S
N
T
S
A
L
A
K
D
F
I
R
R
L
L
V
K
D
P
K
K
R
M
-----
T
I
Q
D
S
L
Q
H
P
W
I
K
P
K
D
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
55.90
24%
-62
- C1 -
-
2X0G
-
DAPK1_HUMAN
A:
[59-279]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
I
E
R
E
V
S
I
L
K
E
I
-
Q
H
P
N
V
I
T
L
H
E
V
Y
E
N
----
K
T
D
V
I
L
I
L
E
L
V
A
G
G
-
E
L
F
D
F
L
A
E
K
E
----
S
----
L
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
-
L
Q
--
I
A
H
F
D
L
K
P
E
N
I
M
L
L
---
D
---
R
---
N
VP
K
P
R
--
I
K
I
I
D
F
G
L
A
H
K
I
D
F
G
N
----------------------------------------------------------------------------------------------------------------------------------------
E
F
K
N
I
F
G
T
P
E
F
V
A
P
E
I
V
N
------
Y
E
-
P
L
G
L
E
A
--
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
-
G
A
S
P
F
L
G
D
T
K
Q
E
---
T
L
A
N
V
S
A
V
N
-------------------
Y
E
---------
F
E
--------------------
D
E
Y
F
S
N
T
S
A
L
A
K
D
F
I
R
R
L
L
V
K
D
P
K
K
R
M
-----
T
I
Q
D
S
L
Q
H
P
W
I
K
P
K
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
55.78
27%
-45
- C1 -
-
3C0I
1
CSKP_HUMAN
A:
[71-294]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
L
K
R
E
A
S
I
C
H
M
L
-
K
H
P
H
I
V
E
L
L
E
T
Y
S
S
----
D
G
M
L
Y
M
V
F
E
F
M
D
G
A
-
D
L
C
F
E
I
V
K
R
A
D
A
G
F
V
----
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
-
N
N
--
I
I
H
R
D
V
K
P
H
C
V
L
L
A
---
S
---
K
ENS
A
----
P
--
V
K
L
G
G
F
G
V
A
I
Q
L
G
E
S
G
---------------------------------------------------------------------------------------------------------------------------------------
L
V
A
G
G
R
V
G
T
P
H
F
M
A
P
E
V
V
K
------
R
E
-
P
Y
G
K
P
V
--
D
V
W
G
C
G
V
I
L
F
I
L
L
S
-
G
C
L
P
F
Y
G
T
K
E
R
----
L
F
E
G
I
I
K
G
K
----
Y
K
M
----------------
N
---------------------------
P
R
Q
W
-
S
H
I
S
E
S
A
K
D
L
V
R
R
M
L
M
L
D
P
A
E
R
I
-----
T
V
Y
E
A
L
N
H
P
W
L
K
E
R
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
55.62
29%
-32
- C1 -
-
5O2C
4
WNK3_HUMAN
A:
[69-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
F
K
E
E
A
E
M
L
K
G
L
-
Q
H
P
N
I
V
R
F
Y
D
S
W
E
S
I
L
K
G
K
K
C
I
V
L
V
T
E
L
M
T
S
G
-
T
L
K
T
Y
L
K
R
F
K
----
V
----
M
K
P
K
V
L
R
S
W
C
R
Q
I
L
K
G
L
Q
F
L
H
T
-
R
T
PP
I
I
H
R
D
L
K
C
D
N
I
F
I
T
G--
P
---
T
---
G
----
S
--
V
K
I
G
D
L
G
L
A
T
L
M
R
T
S
-----------------------------------------------------------------------------------------------------------------------------------------
F
A
K
S
V
I
G
T
P
E
F
M
A
P
E
M
Y
E
-------
E
-
H
Y
D
E
S
V
--
D
V
Y
A
F
G
M
C
M
L
E
M
A
T
-
S
E
Y
P
Y
S
E
C
Q
N
A
A
Q
--
I
Y
R
K
V
T
S
G
I
-----------------------
K
---------------------------
P
A
S
F
N
K
V
T
D
P
E
V
K
E
I
I
E
G
C
I
R
Q
N
K
S
E
R
L
-----
S
I
R
D
L
L
N
H
A
F
F
A
E
D
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
55.60
17%
-12
- C1 -
-
1KOB
1
?
A:
[23-374]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
D
Y
D
K
F
Y
E
D
I
W
K
K
Y
V
P
Q
P
V
E
V
K
Q
G
S
V
Y
---
D
Y
Y
D
I
L
E
E
L
G
S
G
A
F
G
V
V
H
R
C
V
E
K
A
T
G
R
V
F
V
A
K
F
I
N
T
P
Y
P
L
D
K
Y
T
V
K
N
E
I
S
I
M
N
Q
L
-
H
H
P
K
L
I
N
-
L
H
D
A
F
E
---
D
K
Y
E
M
V
L
I
L
E
F
L
S
G
G
E
L
F
D
R
I
A
A
E
D
Y
----
K
----
M
S
E
A
E
V
I
N
Y
M
R
Q
A
C
E
G
L
K
H
M
H
E
-
H
S
--
I
V
H
L
D
I
K
P
E
N
I
M
C
E
---
T
---
K
KA-
S
----
S
--
V
K
I
I
D
F
G
L
A
T
K
L
----------------------------------------------------------------------------------------------------------------------------------------
N
P
D
E
I
V
K
V
T
T
A
T
A
E
F
A
A
P
E
I
V
D
------
R
E
-
P
V
G
F
Y
T
--
D
M
W
A
I
G
V
L
G
Y
V
L
L
S
G
----
L
S
P
F
A
G
E
D
D
L
E
T
L
Q
N
V
K
R
C
D
W
E
F
D
E
D
A
F
S
S
V
------------------------------------------------
S
P
E
A
K
D
F
I
K
N
L
L
Q
K
E
P
R
K
R
L
-----
T
V
H
D
A
L
E
H
P
W
L
K
G
D
H
S
N
L
T
S
R
I
P
S
S
R
Y
N
K
I
R
Q
K
I
K
E
K
Y
A
D
W
P
A
P
Q
P
A
I
G
R
I
A
NFS
S
L
R
K
H
R
P
Q
E
Y
Q
I
Y
D
S
Y
F
D
R
K
E
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
55.45
27%
-42
- C1 -
-
3C0G
1
CSKP_HUMAN
B:
[71-294]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
L
K
R
E
A
S
I
C
H
M
L
-
K
H
P
H
I
V
E
L
L
E
T
Y
S
S
----
D
G
M
L
Y
M
V
F
E
F
M
D
G
A
-
D
L
C
F
E
I
V
K
R
A
D
A
G
F
V
----
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
-
N
N
--
I
I
H
R
D
V
K
P
H
C
V
L
L
A
---
S
---
K
ENS
A
----
P
--
V
K
L
G
G
F
G
V
A
I
Q
L
G
E
S
G
---------------------------------------------------------------------------------------------------------------------------------------
L
V
A
G
G
R
V
G
T
P
H
F
M
A
P
E
V
V
K
------
R
E
-
P
Y
G
K
P
V
--
D
V
W
G
C
G
V
I
L
F
I
L
L
S
-
G
C
L
P
F
Y
G
T
K
E
R
----
L
F
E
G
I
I
K
G
K
----
Y
K
M
----------------
N
---------------------------
P
R
Q
W
-
S
H
I
S
E
S
A
K
D
L
V
R
R
M
L
M
L
D
P
A
E
R
I
-----
T
V
Y
E
A
L
N
H
P
W
L
K
E
R
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
54.66
26%
-33
- C1 -
-
2Y7J
1
PHKG2_HUMAN
C:
[144-364]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
T
R
R
E
T
H
I
L
R
Q
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
S
----
S
S
F
M
F
L
V
F
D
L
M
R
K
G
-
E
L
F
D
Y
L
T
E
K
V
----
A
----
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
-
N
N
--
I
V
H
R
D
L
K
P
E
N
I
L
L
D
---
D
---
N
---
M
----
Q
--
I
R
L
S
D
F
G
F
S
C
H
L
E
P
G
E
----------------------------------------------------------------------------------------------------------------------------------------
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
CSMDET
H
P
-
G
Y
G
K
E
V
--
D
L
W
A
C
G
V
I
L
F
T
L
L
A
-
G
S
P
P
F
W
H
R
R
Q
I
L
---
M
L
R
M
I
M
E
G
Q
----
Y
Q
F
---------------
S
S
----------------------------
P
E
-
W
D
D
R
S
S
T
V
K
D
L
I
S
R
L
L
Q
V
D
P
E
A
R
L
-----
T
A
E
Q
A
L
Q
H
P
F
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
53.55
31%
0
- C- -
-
2WEL
7
KCC2D_HUMAN
A:
[49-271]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
E
R
E
A
R
I
C
R
L
L
-
K
H
P
N
I
V
R
L
H
D
S
I
S
E
----
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
-
E
L
F
E
D
I
V
A
R
E
----
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
-
N
G
--
I
V
H
R
D
L
K
P
E
N
L
L
L
A
---
S
---
K
SKG
A
----
A
--
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
---------------------------------------------------------------------------------------------------------------------------------------
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
R
------
K
D
-
P
Y
G
K
P
V
--
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
-
G
Y
P
P
F
W
D
E
D
Q
H
R
---
L
Y
Q
Q
I
K
A
G
A
-----------------
Y
-----
D
----------
F
P
----------------
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
-----
T
A
S
E
A
L
K
H
P
W
I
C
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
52.92
26%
-38
- C1 -
-
2Y7J
1
PHKG2_HUMAN
D:
[144-364]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
T
R
R
E
T
H
I
L
R
Q
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
S
----
S
S
F
M
F
L
V
F
D
L
M
R
K
G
-
E
L
F
D
Y
L
T
E
K
V
----
A
----
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
-
N
N
--
I
V
H
R
D
L
K
P
E
N
I
L
L
D
---
D
---
N
---
M
----
Q
--
I
R
L
S
D
F
G
F
S
C
H
L
E
P
G
E
----------------------------------------------------------------------------------------------------------------------------------------
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
CSMDET
H
P
-
G
Y
G
K
E
V
--
D
L
W
A
C
G
V
I
L
F
T
L
L
A
-
G
S
P
P
F
W
H
R
R
Q
I
L
---
M
L
R
M
I
M
E
G
Q
----
Y
Q
F
---------------
S
S
-----------------------------
P
E
W
D
D
R
S
S
T
V
K
D
L
I
S
R
L
L
Q
V
D
P
E
A
R
L
-----
T
A
E
Q
A
L
Q
H
P
F
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
51.96
28%
-66
- C1 -
-
4NIF
-
KS6A1_HUMAN
A:
[58-270]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
-
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
----
G
K
H
V
Y
L
V
T
E
L
M
R
G
G
-
E
L
L
D
K
I
L
R
Q
K
----
F
----
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
-
Q
G
--
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
---
D
---
E
---
S
GNPE
C
--
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
---------------------------------------------------------------------------------------------------------------------------------------
G
L
L
M
T
P
C
Y
---
F
V
A
P
E
V
L
K
------
R
Q
-
G
Y
D
E
G
C
--
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
-
G
Y
T
P
F
A
N
G
P
S
D
T
P
E
E
I
L
T
R
I
G
S
G
K
-----------------
F
T
L
------------------------------
S
G
G
N
W
-
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
-----
T
A
K
Q
V
L
Q
H
P
W
V
T
Q
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
48.46
14%
6
- C1 -
-
3C4Z
1
RK_BOVIN
A:
[31-533]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
R
K
Y
L
A
R
L
K
L
P
P
L
S
K
C
E
A
L
R
E
S
L
D
L
G
F
E
G
M
C
L
E
Q
P
I
G
K
R
L
F
Q
Q
F
L
R
T
H
E
Q
H
G
P
A
L
Q
L
W
K
D
I
E
D
Y
D
T
A
-
D
D
A
L
R
P
Q
K
A
Q
A
L
R
A
A
Y
L
E
P
Q
A
Q
L
F
C
S
F
L
D
A
E
T
V
A
R
A
R
A
G
G
L
F
Q
P
L
L
R
A
V
L
A
H
L
G
Q
A
P
F
Q
E
F
L
D
S
L
Y
F
L
R
F
L
Q
W
K
W
L
E
A
Q
P
M
G
E
D
W
F
L
D
F
R
V
L
G
RGG
F
G
E
V
F
A
C
Q
M
K
A
T
G
K
L
Y
A
C
K
K
L
N
K
K
R
L
K
K
R
K
G
Y
Q
G
A
M
V
E
K
K
I
L
A
K
------------
V
H
S
R
F
I
V
S
L
A
Y
A
F
E
---
T
K
T
D
L
C
L
V
M
T
I
M
N
G
G
-
D
I
R
Y
H
I
Y
N
V
D
----
E
D
N
P
G
F
Q
E
P
R
A
I
F
Y
T
A
Q
I
V
S
G
L
E
H
L
H
Q
-
R
N
--
I
I
Y
R
D
L
K
P
E
N
V
L
L
D
---
D
---
D
---
G
----
N
--
V
R
I
S
D
L
G
L
A
V
E
L
K
A
G
Q
T
K
T
K
G
Y
A
G
T
P
G
----
F
M
A
P
E
L
L
L
--
G
E
E
Y
D
F
S
V
D
Y
F
A
L
G
V
T
L
Y
E
M
I
A
A
R
G
P
FR
A
R
G
E
K
V
E
N
K
E
L
K
Q
R
V
L
E
Q
A
V
T
Y
P
DKF
S
P
A
S
K
D
F
C
E
A
L
L
QKDPEKRLGFRD
G
S
C
D
G
L
R
T
H
P
L
F
R
-
D
I
S
W
R
Q
L
E
A
G
M
L
T
P
P
F
V
P
D
S
R
T
V
Y
A
K
N
G
A
F
S
G
V
A
F
E
K
------
A
D
-
T
E
F
F
Q
E
F
A
S
G
T
C
P
I
P
W
Q
E
E
M
I
E
T
G
V
F
G
D
L
N
V
W
R
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------