@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : M_TH16_EuGene_00079591: (2018-03-21 )
NEDCIVSLVPDGGSFARKTLRSSPGQQHDLQWGKYAFTIRVENGCAGKKTAGTIPPAHFVSVGRAASLKPTSILRDGDPRPPTAVYPPRQPPRTEGRRTRYGSSGGAVTVGAR
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...---......10----....--....-.20..--.-----....--.30........40...--...--..50------.----.......60-.---..----....-----.---.70---.-.------.-......-80..-.-.....90..--....--...100-------...--.--...110.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NE
D
---
C
I
V
S
LVP-----DG
G
S
--
F
A
R
K
-
T
L
RSS--P-----GQQH--DLQWG
K
Y
A
F
T
I
R
VENG--CAG--KKTA------G----TIP
P
A
H
F
V
--S---VG----RAAS-----L---KP----
T
-
S
------I-LRDGDP-RPPT-A-VYPPRQ-PP--RTEG--RRTRYG-------SSG--G--
A
V
T
VGAR
11
Fugue
71.47
26%
-24
- C6 -
-
2EEB
-
A:
[1-106]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
S
-----
S
G
S
D
--
D
A
R
R
-
L
T
V
M
S
--
L
-----
Q
E
S
G
--
L
K
V
N
Q
P
A
S
F
A
I
R
L
-
N
G
--
A
K
G
--
K
I
D
A
------
K
----
V
H
S
P
S
G
A
V
--
E
---
E
C
----
H
V
S
E
-----
L
---
E
P
----
D
------------------------
K
Y
A
V
R
F
-
I
P
--
H
E
N
G
--
V
H
T
I
D
V
-------
K
F
N
--
G
--
S
H
V
V
G
S
P
14
Fugue
62.05
26%
61
- C7 -
-
4CCZ
1
METH_HUMAN
A:
[4-638]
TLRDEINAILQKRIMVLDGGMGTMIQREKLEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGK
C
T
T
---
A
Y
V
L
C
Y
P
-----
N
A
G
---
F
A
M
D
-
G
L
---------------------------
V
N
I
V
G
G
--
C
C
G
--
S
T
----------------
P
D
H
I
R
--
E
---
I
A
----
E
A
V
----------------------------
K
N
C
K
P
-
R
V
P
P
-
A
-
T
A
F
E
G
H
-
M
L
--
L
S
G
L
--
E
P
F
R
I
G
-------
P
Y
T
--
N
--
F
V
N
I
G
E
R
20
Fugue
61.76
20%
73
- C4 -
-
4D0L
2
PI4KB_HUMAN
A:
[10-566]
----------------------------------------------------------------------------------------------------------------------------SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQK
T
Q
R
---
L
I
S
E
L
S
L
-----
L
N
H
K
--
L
P
A
R
-
V
W
L
P
T
--
A
-----
G
F
D
H
--
H
V
V
R
V
P
H
T
Q
A
V
V
L
-----------
N
S
K
------
D
----
K
A
P
Y
L
I
Y
V
--
E
---
V
L
----
E
C
E
N
-----
F
---
D
T
----
T
-
S
------
V
--
P
A
R
I
P
-
E
N
P
S
-
A
-
V
-
A
L
K
E
-
P
W
--
Q
E
K
V
--
R
R
I
R
E
G
-------
S
P
Y
--
G
--
H
L
P
-
N
W
R
22
SP3
61.41
16%
15
- C6 -
-
1BAW
-
PLAS_PHOLA
A:
[1-105]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
---
F
T
V
K
M
G
A
-----
D
S
G
L
LQ
F
E
P
A
-
N
V
T
V
H
--
P
-----
G
D
-------------
T
V
K
W
V
N
----------
N
K
------
L
----
P
P
H
N
I
L
F
D
DK
Q
---
V
P
----
G
A
S
K
-----
E
---
L
A
----
D
-
K
------
L
-
S
H
S
Q
L
M
-
F
S
P
G
-
E
-
S
Y
--
E
I
-
T
F
--
S
S
D
F
--
P
A
G
T
Y
T
YYCAPHR
G
A
G
MV
G
--
K
I
T
V
E
G
-
30
SP3
58.69
17%
-15
- C6 -
-
1L5P
1
FER_TRIVA
A:
[1-93]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
---
T
I
T
A
V
K
-------
G
G
V
----
K
K
-
Q
L
K
F
E
--
D
-----
D
Q
T
----------
L
F
T
V
L
T
E
A
G
LM
S
A
D
--
D
T
C
Q
------
G
----
N
K
A
C
G
K
C
I
--
C
---
K
H
----
V
S
G
K
-----
V
---
A
A
----
A
------------
E
D
D
E
-
K
E
F
L
-
E
-
D
Q
P
A
N
A
-----
R
L
A
C
--
A
I
T
L
S
G
-------
E
N
D
--
G
--
A
V
F
E
L
--
23
SP3
57.62
18%
35
- C6 -
-
1PLC
-
?
?:
[1-99]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
V
L
L
G
A
-----
D
D
G
S
LA
F
V
P
S
-
E
F
S
I
S
--
P
-----
G
E
-------------
K
I
V
F
K
N
----------
N
A
------
G
----
F
P
H
N
I
V
F
D
ED
S
---
I
P
----
S
G
V
D
-----
A
---
S
-----------------
K
I
S
M
S
-
E
E
D
L
-
L
-
N
A
K
G
E
T
-
F
E
--
V
A
L
S
--
N
K
G
E
Y
S
FYCSPHQ
G
A
G
MV
G
--
K
V
T
V
N
--
16
Fugue
57.18
17%
86
- C7 -
-
2CO5
-
?
A:
[5-96]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYMRIN
Y
Y
I
---
I
L
K
V
L
V
I
-----
N
G
S
R
--
L
E
K
K
-
R
L
R
S
E
--
I
-----
L
K
R
F
--
D
--------------------------------------
I
D
I
S
D
G
V
--
L
---
Y
P
----
L
I
D
S
-----
L
---
I
D
----
D
-
K
------
I
-
L
R
E
E
E
A
-
P
D
G
K
-
V
-
L
F
L
T
E
K
-
G
M
--
K
E
F
E
--
E
L
H
E
F
F
-------
K
K
I
--
V
--
C
---
H
H
H
15
Fugue
56.11
17%
-24
- C7 -
-
4G6V
-
CDII2_BURP2
B:
[2-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
D
---
L
F
C
Y
L
S
I
-----
D
R
G
A
--
A
E
S
D
-
L
N
K
I
R
--
S
-----
N
H
S
E
--
L
F
E
-
G
K
F
L
I
S
P
V
R
D
A
D
--
F
S
L
--
K
E
I
A
------
A
EHGL
V
A
E
S
F
F
L
V
--
S
---
L
N
----
D
K
N
S
-----
A
---
D
L
IPIV
S
-
K
------
I
-
L
V
D
G
F
N
-
G
G
A
I
-
L
-
I
L
Q
D
N
E
-
Y
R
--
R
T
S
L
------------------------------
21
SP3
55.99
8%
14
- C5 -
-
1BF2
-
?
?:
[638-750]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y
S
G
S
---
Q
L
T
W
Y
Q
P
-----
S
G
A
----------
V
A
D
--
S
-----
N
Y
W
N
--
N
-
T
S
N
Y
-
A
I
A
Y
A
I
N
G
P
--
S
L
G
--
D
S
N
S
IYVAYN
G
----
W
S
S
S
V
T
F
T
--
L
---
P
A
----
P
P
S
G
-----
T
---
Q
W
----
Y
-
R
------
V
-
T
D
T
C
D
W
N
D
G
A
S
-
T
-
F
V
A
P
G
S
-
E
T
--
L
I
---------
G
-------
G
A
G
--
T
--
T
Y
G
Q
C
G
Q
25
SP3
54.94
15%
101
- C6 -
-
1IFR
1
A:
[1-113]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSHRTS
G
R
V
---
A
V
E
E
V
D
E
-----
E
-
G
K
--
F
V
R
---
L
R
N
K
--
S
-----
N
E
D
Q
--
S
M
G
-
N
---
W
Q
I
K
R
Q
N
G
----
D
--
D
P
L
L
------
T
----
Y
R
F
P
P
K
F
T
------
L
K
----
A
G
Q
V
-----
V
---
T
I
----
W
-
A
------
A
-
G
A
G
A
T
H
-
S
P
P
T
-
D
L
V
W
K
A
Q
N
-
T
W
--
G
C
G
N
SL
R
T
A
L
I
N
-------
S
T
G
--
E
--
E
V
A
M
R
K
L
12
Fugue
54.32
15%
8
* C7 *
-
5TPM
-
PDHR_ECOLI
A:
[1-155]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SN
A
D
L
---
L
E
T
R
H
A
L
-----
E
G
I
A
--
A
Y
Y
A
-
A
L
R
S
T
--
D
-----
E
D
K
E
--
R
I
R
E
L
H
H
A
I
E
L
A
Q
Q
S
G
--
D
L
D
--
A
E
S
N
------
A
----
V
L
Q
Y
Q
I
A
V
--
T
---
E
A
AHNV
V
L
L
H
-----
L
---
L
R
----
C
M
E
------
P
M
L
A
Q
N
V
R
-
Q
N
F
E
-
L
-
L
Y
S
R
R
E
M
L
P
--
L
V
S
S
--
H
R
T
R
I
F
-------
E
A
I
M-
A
--
G
K
P
E
E
A
R
27
SP3
52.56
16%
23
- C6 -
-
1KLF
-
FIMH_ECOLI
B:
[159-279]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGCDVS
A
R
D
---
V
T
V
T
L
P
D
-----
Y
P
G
S
--
V
P
I
P
L
T
V
Y
C
A
--
K
-----
S
Q
---------
N
L
G
Y
Y
L
S
---
G
--
T
T
A
--
D
A
G
N
------
S
----
I
F
T
N
T
A
S
F
--
S
---
P
A
----
Q
G
V
G
-----
V
QLT
R
N
----
G
-
T
------
I
-
I
P
A
N
N
T
-
V
S
L
G
-
A
-
V
G
---
T
-
S
A
--
V
S
L
G
--
L
T
A
N
Y
A
-------
R
T
G
--
G
--
Q
V
T
A
G
N
V
24
SP3
49.18
12%
33
- C6 -
-
1KDJ
-
?
?:
[1-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
V
E
V
G
D
-----
E
V
G
N
FK
F
Y
P
D
-
S
I
T
V
S
--
A
-----
G
E
-------------
A
V
E
F
T
L
----------
V
G
------
E
----
T
--
G
H
N
I
V
--
F
---
D
I
----
P
A
G
A
-----
P
---
G
T
----
V
-
A
------
S
-
E
L
K
A
A
S
-
M
D
E
N
-
D
-
L
L
S
E
D
E
-
P
S
FK
A
K
V
S
--
T
P
G
T
Y
T
FYCTPHK
S
A
N
MK
G
--
T
L
T
V
K
--
26
SP3
46.80
15%
-3
* C6 *
-
1AKP
-
?
?:
[1-114]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
---
A
A
V
S
V
S
P
ATGLA
D
G
A
T
--
V
T
V
S
-
A
S
G
F
A
--
T
-----
S
T
S
A
--
T
A
--
L
Q
C
A
I
---
L
A
D
G
--
R
G
A
--
C
N
V
A
--------------
E
F
H
D
F
--
S
---
L
S
----
G
G
E
G
TTSVV
V
---
R
R
----
S
-
F
------
T
-
G
Y
V
M
P
D
-
G
P
E
V
G
A
-
V
D
C
D
T
A
-
P
G
--
G
C
E
I
--
V
V
G
G
N
T
-------
G
E
Y
--
G
NA
A
I
S
F
G
--
29
SP3
46.72
14%
54
- C6 -
-
1UM1
-
A:
[1-110]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSSGSS
G
Y
V
---
F
T
V
E
L
E
R
-----
G
P
S
G
--
L
G
-
M
-
G
L
I
D
G
--
M
-----
H
T
H
L
--
G
A
P
-
G
L
Y
I
Q
T
L
-
L
P
G
S
--
P
A
---
A
A
D
G
------
R
----
L
S
L
G
D
R
I
L
--
E
---
V
-----
N
G
S
S
-----
L
---
L
G
----
L
-
G
YLRAVD
L
-
I
R
H
G
G
K
-
K
M
R
F
-
L
-
V
A
K
S
D
V
-
E
T
--
A
K
K
I
--
H
S
G
--
P
-------
S
S
G
------------
6
HHSearch
46.11
22%
9
* C8 *
-
5M12
-
AGAL_THEMA
A:
[15-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
-----
R
G
S
H
--
M
A
S
M
-
E
I
F
G
K
--
T
-----
F
R
E
G
RF
V
L
K
E
K
N
F
T
V
E
F
A
V
E
K
I
--
H
L
G
--
W
K
I
S
------
G
----
R
V
K
----------------------------------------------------------------------------------------------------------
7
HHSearch
44.86
22%
2
- C8 -
-
5M1I
2
AGAL_THEMA
A:
[13-63]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
P
-----
R
G
S
H
--
M
A
S
M
-
E
I
F
G
K
--
T
-----
F
R
E
G
RF
V
L
K
E
K
N
F
T
V
E
F
A
V
E
K
I
--
H
L
G
--
W
K
I
S
------
G
----
R
V
K
----------------------------------------------------------------------------------------------------------
28
SP3
44.02
15%
43
- C3 -
-
2PF1
-
?
?:
[36-156]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
A
T
D
AFW
A
K
Y
T
A
C
E
-----
S
A
R
N
--
P
R
E
K
-
L
N
E
C
L
--
E
GNCAE
G
V
G
M
--
N
Y
R
-
G
N
V
S
V
T
---
R
S
G
--
I
E
C
--
Q
L
W
R
------
S
----
R
Y
P
H
K
P
E
I
--
N
STT
H
P
----
G
A
D
L
-----
R
---
E
N
----
F
-
C
------
R
-
N
P
D
G
S
I
-
T
G
P
W
-
C
-
Y
T
T
S
P
T
-
L
R
--
R
E
E
C
--
S
V
P
V
C
G
-------
Q
D
R
--
V
--
T
V
E
V
I
P
R
9
HHSearch
43.41
23%
19
- C9 -
-
2QLX
7
RHAM_RHILT
B:
[6-50]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
H
A
F
K
M
Q
L
N
P
G
--
M
E
A
EY
R
K
R
H
------
D
----
E
I
W
P
E
L
V
D
--
L
---
L
-----
H
Q
S
G
-----
A
---
S
D
----
Y
-
S
------
I
-
H
L
D
--------------------------------------------------------
10
HHSearch
41.70
44%
-7
- C1 -
-
4XJ6
2
?
A:
[109-170]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
G
S
--
F
Q
Y
D
-
T
L
N
R
P
FH
P
-----
G
Q
E
M
--
D
I
D
D
G
T
Y
--------------------------------------------------------------------------------------------------------------------------------------------