@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CB044_HUMAN: (2018-07-12 )
MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSGEVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQTCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHSDDSQVKADINTQGRIHCACWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATELPLDKICGLNASETFNIPPNSKDMTPYALPVIGEVRSMDKEATDSETNSEVSVSSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVTIPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLTDQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLEEEPSITSGESQTTYSTFSAPLNKANRKKLIESLSPDFCHQNKGLLLTVNTSSQNGRPGRTLIKEIQSPLSSICDGSIALDAEPVTQPASLPRHSSTPDHTSTLEPPRLPQRKNLQSEKETYQLSKEVEILSRNLVEMQRCLSELTNRLHNGKKSSSVYPLSQDLPYVHIIYQKPYYLGPVVEKRAVLLCDGKLRLSTVQQTFGLSLIEMLHDSHWILLSADSEGFIPLTFTATQEIIIRDGSLSRSDVFRDSFSHSPGAVSSLKVFTGLAAPSLDTTGCCNHVDGMA

Atome Classification :

(20 SA) .........10........20........-30........-------------40-------.----.----..-.....---50---.--.-------------.--------..-..----.-.60........70........80-.---.--.----.-----.....90........100..-....--------.---110.......120.......130---.------.--.-----------------------------------....140.....--.---------.150----..-.-.-----------.....160......---.170....---.-.----.180.......190.......200.......210....-...220.......230.......240......-.250.......260.......270.......280.......290.......300........310.......320.......330..-.....340.....--..350.......360.......370.--......380.......390.......400.......410.......420.......430.......440.......450..------.....460.......470.......480.......490.......500.......510.......520.......530.......540-.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640..--.....650.......660.......670.......680.......690.......700--.......710.......720
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MELGKGKLLRTGLNALHQAVHPIHGLAWT-DGNQVVLTDL-------------R--------L----H----SG-EVKFG---D----S--K-------------V--------IG-QF----E-CVCGLSWAPPVADDTPVLLAVQ--H---E--K----H-----VTVWQLCPSPMESSKWLTSQ-TCEI--------R---GSLPILPQGCVWHPKCAILTVLT---A------Q--D-----------------------------------VSIFPNVHSDDS--Q---------VK------AD-I-N-----------TQGRIHCACWTQDG---LRLVVAVG---S-S----LHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQ-VAIATELPLDKICGLNASETFNIPPNSKDMTP-YALPVIGEVRSMDKEATDSETNSEVSVSSSYLEPLDLTHIHFNQHKSEGNSLI-CLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKV-TIPGILVPDLIAF--NLKAHVVAVASNTCNIILIYSVIPSS--VPNIQQIRLENTERPKGICFLTDQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLEEEPSITSGESQTTYSTFSAP------LNKANRKKLIESLSPDFCHQNKGLLLTVNTSSQNGRPGRTLIKEIQSPLSSICDGSIALDAEPVTQPASLPRHSSTPDHTSTLEPPRL-PQRKNLQSEKETYQLSKEVEILSRNLVEMQRCLSELTNRLHNGKKSSSVYPLSQDLPYVHIIYQKPYYLGPVVEKRAVLLCDGKLRLSTVQQTFGLSLIEML--HDSHWILLSADSEGFIPLTFTATQEIIIRDGSLSRSDVFRDSFSHSPGAVSSLKVFTG--LAAPSLDTTGCCNHVDGMA
45 Fugue 61.8417% -6 - C1 - - 2BMF - ? A:[169-618] ------------------------------------------------------------------------------------------------------------------------------------MASIEDNPEIEDDIF--R---K--K----R-----LTIMDLHPGAGKTKRYLPAI-VREA--------I---KR----------GLRTLILAP-------------------------------------------------------------TR--V---------VA------AE-M-E-----------EALRGLPIRYQTGR---EIVDLMCH---A-T----FTMRLLSPIRVPNYN----LIIMDEAHF-TDPASIAAR-GYISTRVEMGEAAGIFMTAT---PPGSRDPFPQSNAPIMDEEREIPERSWNS--------GHEWVTDFKGKTVWFVPSIKAGNDIAACLRKN------GKKVIQLSRKTFDSEYIKTRTN-DWDFVVTTDISEMGANFKAERV-IDPRRCMKPVILTDGEER--VILAGPMPVTHSSAAQRRG---------RVGRN--------PKNENDQYIYM---GEPLENDEDCAHWKEAKMLLDNINTPEGIIPSMFEPEREK-VDAIDGEYRLRGEARKTFVDLMRRGDLP-VWLAYRVAAEGINYADRRWCFDG--VKNNQILEENVEVEIWTKEGERKKLKPRWLDARIYSDPLALKEFKEFAAGRK-------------------------------------------------------------------------------------------------------------------------------------------------------------
22 HHSearch 49.6913% -12 * C3 * - 1RI6 - 6PGL_ECOLI A:[39-334] -----------------------------------------------------------------------------------------------------------------------------QVQPMVVSPDKR-----YLYVG--V---RPEF----R-----VLAYRIAPDDG---ALTFAA-E---------------SALPGSLTHISTDHQGQFVFVGS---Y------NAGN-----------------------------------VSVTRLE--DGL--P---------VGV-----VD-VVE-----------GLDGCHSANISPDN---RTLWVPAL---K-QDR--ICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNEL--N-----SSVDVWELKDPHGNI---E--CVQ-T---LD-------MMPEN-----FSDTRWAADIHITP-------------DGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNV--DHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKG--RYAVGQGPMWVVVNAHE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 HHSearch 46.4413%-127 - C3 - - 4QRJ ? A:[294-348] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPRNFNI--TPNGKYLLAACRDSNVIQVYKRNEVT--GLLEDTHQDIVVDMPVCVQFVS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39 HHSearch 44.9310% 6 - C3 - - 4G56 - MEP50_XENLA B:[43-213] --------------------VQIGAVRYRRDGALLLAASS-------------L--------S----SRTW-GG-SIWVF---KDPE-------------------NESLCTAGVQ-TE----A-GVTDVAWVSEKG-----ILVAS--D---S--G----A-----VELW-----------LVNKF---AK------------YEHDDIVKTLSVFSDGTQAVSGG---KD-----F--S-----------------------------------VKVWDLS--QKA--V---------LK------SY-N-A-----------HSSEVNCVAACPGK---DTIFLSCG---E-D----GRILLWDTRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 Fugue 44.528% 30 * C2 * - 1NR0 - WDR1_CAEEL A:[2-611] SEFSQTALFPSLPRTARGTAVVL---GNT-PAGDKIQYCN-------------G--------T----S----VY-TVPVG---SLTDTE--I-------------Y--------TE-HS----H-QTTVAKTSP----SGYYCASGD--V---H--G----N-----VRIWDTTQTTHILKTTIPVF-SGPV--------K----DISWDSESK------RIAAVGE---G------R--E-----------------------------------RFGHVFLFDTGT--S---------NG------NL-T-G-----------QARAMNSVDFKPSR---PFRIISGS---D-D----NTVAIFEGPPFKFKSTFGEH----TKFVHSVRYNPDGS-LFAST---------------------GGDGTI-VLYNG---------------------VDGTKTGVFEDDSLKNVAHSGSVFGLT-WSPDGTKIASASADKTIKIWNVATL--KVEKTI-PVGTRIEDQQLGI--IWTKQALVSISAN-------------------GFINFVNPELGSIDQVRYGHNKAITALSSSADGKTLFSADAEGH------INSWDISTGISNRVFPDVHATMITGIK------TTSKGD---LFTVSWD------DHLKVVPAGGSGVDSSKAVANKLSSQ------------PLGLAVSADGDIAVAACYKHIAIYSHGK-LTEVPISYNSSCVALSNDKQFVAVGGQDSKVHVYKLSGA-----------SVSEVKTIVHPAEITSVAFSNNGAFLVATDQSRKVIPYSVANNFELAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNKPSDHPIIIKGAHAMSSVNSVIWLNETTIVSAGQDSNIKFWNVPF--
40 HHSearch 44.1210% 9 - C3 - - 4G56 - MEP50_XENLA D:[43-213] --------------------VQIGAVRYRRDGALLLAASS-------------L--------S----SRTW-GG-SIWVF---KDPE-G--A-------------PNESLCTAGVQ-TE----A-GVTDVAWVSEKG-----ILVAS--D---S--G----A-----VELWEILEKES---LLVNKF---AK------------YEHDDIVKTLSVFSDGTQAVSGG---KD-----F--S-----------------------------------VKVWDLS--QKA--V---------LK------SY-N-A-----------HSSEVNCVAACPGK---DTIFLSCG---E-D----GRILLWDTRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 HHSearch 41.7212% -7 - C3 - - 3SCY ? A:[6-183] ------------------------DPSTTDSELTMLVGTY-------------TSGNSKGIYT----F----RF-NEETG---E----SLPL-------------S--------DA-EV----A-NPSYLIPSADGK-----FVYSV--N---E--F----SKDQAAVSAFAFDKEKG---TLHLLN-T----------------QKTMGADPCYLTTNGKNIVTAN---YSG----G--S-----------------------------------ITVFPIGQDGALL-P---------AS------DV-I-EFKGSGPDKERQTMPHLHCVRITPDG---KYLLADDL---G-T----DQIHKFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 HHSearch 41.2215% -41 - C3 - - 3U4Y ? A:[85-249] ---------------------SMADVDITPDDQFAVTVTG-------------L--------N----H----PF-NMQSYSFLK----N--K-------------F--------IS-TIPIP-Y-DAVGIAISPNGN-----GLILI--DRSSA--N----T-----VRRFKIDADGV---LFDTGQ----E--------F---ISGGTRPFNITFTPDGNFAFVAN---LIG----N--S-----------------------------------IGILETQ--NPE--N---------ITL-----LNAV-G-----------TNNLPGTIVVSRDG---STVYVLTE---S-T----VDVFNFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 40.5012% -34 - C3 - - 5I2T - PWP2_YEAST A:[35-302] ---------------LLGTVYRQGNITFSDDGKQLLSPVG-------------NRVS-----V----F----DL-I-------N----N--K-------------S--------FT-FEYEHRK-NIAAIDLNKQGT-----LLISI--D---ED-G----R-----AILVNFKARNV---LHH-----F---------------NFKEKCSAVKFSPDGRLFALAS---G------R--F-----------------------------------LQIWKTPDVNKDR-Q---------FAPFVRHRVH-A-G-----------HFQDITSLTWSQDS---RFILTTSK---D-LS---AKIWSVDSEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48 Fugue 39.8431% -90 * C1 * - 1ZVZ - B:[2-23] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMVRQARILAQATSDLVNAIKA-----------------------------------------------------------------------------------------------------------------------------------------
41 HHSearch 39.7912% -4 - C3 - - 5OLJ ? A:[91-311] ---------------------QIQNYEVSSTGHHILLFTDMESIYRHSYRAAVY--------D----Y----DV---RRN---L----V--K-------------P--------LSEHV----G-KVMIPTFSPDGR-----MVAFV--R---D--N----N-----IFIKKFDFDTE--VQVTTDGQINSVLNGATDWVY---EEEFGVTNLMSWSADNAFLAFVR---S------D--ESAVPEYRMPMYEDKLYPEDYTYKYPKAGEKNSTVSLHLYNVADRNTK--S---------VS------LP-I-D-----------ADGYIPRIAFTDNA---DELAVMTL---N-RLQNDFKMYYVHPKS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 HHSearch 39.507% -27 - C3 - - 5A5U - EIF3I_YEAST I:[10-182] -------------------ERPLTQVKYNKEGDLLFSCSK-------------DSSAS----V----W----YSLNGERL---G-------T-------------L--------DG-HT----G-TIWSIDVDCFTK-----YCVTG--S---AD-Y----S-----IKLWDVSNGQC---VAT-------W-------------KSPVPVKRVEFSPCGNYFLAIL---DNVMKNPG--S-----------------------------------INIYEIERDSAT--HELTKVSEEPIHKI----IT-H-E-----------GLDAATVAGWSTKG---KYIIAGHK---D-G-----KISKYDV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 HHSearch 37.168% -7 - C3 - - 4QRJ ? A:[93-281] ---------------------GADPCYVATNGREVLTANY-------------SGGTMS---V----F----PLQKDGTL---A----P--ADTLFQGSATGPDAI--------RQ-AT----P-HIHCTVFSPDGK-----YIFATDFS---A--D----R-----ILRFVMHPDNPIPHA-SLE----AV--------G---IEADSGPRHLTFSPNGKFAYLIT---ELS----G--K-----------------------------------VIAFSYDDGCLE--Q---------IQT-----IT-A-DTV---------AARGSADIHLSPDG---KYLYASNRLKED-G----IAIFAVNPENG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 HHSearch 36.8116% -31 - C3 - - 3U4Y ? A:[40-206] --------------------YDFVDTAITSDCSNVVVTSD-------------FCQTLV---Q----I----ET-QLEPP---K----V--V-------------A--------IQ-EG----QSSMADVDITPDDQ-----FAVTV--T---G--LNHPFN-----MQSYSFLKNKF---IS-------TI-------------PIPYDAVGIAISPNGNGLILIDRSSA------N--T-----------------------------------VRRFKIDADG-V--L---------FDTGQ---EF-I-S-----------GGTRPFNITFTPDG---NFAFVANL---I-G----NSIGILETQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44 Fugue 36.3829% -9 - C1 - - 1FMH GCN4_YEAST A:[1-31] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAQ-LEKEVAQAEAENYQLEQEVAQLEHECG------------------------------------------------------------------------------------------------------------------------------------------------------------
38 HHSearch 36.2013% -54 - C3 - - 5A9Q - NUP43_HUMAN I:[76-245] -----------------------------------------------------------------------------------------------------------------------------DVMDLQFFDQER-----IVAAS--S---T--G----C-----VTVFLHHPNNQTLSVNQ--Q-WTTA--------HYHT----SSAPCTGVVCNNPEIVTVG---ED-----G--R-----------------------------------INLFRAD--HKE--A---------VRT-----ID-N-A-----------DSSTLHAVTFLRTP---EILTVNSI---G-Q----LKIWDFRQQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 HHSearch 35.9915% -49 - C3 - - 2CE8 - TLE1_HUMAN A:[10-170] --------------------KPAYSFHVTADGQMQPVPFP-------------P--------DALIGP----GI-PRHAR---Q----I--N-------------T--------LN-HG----E-VVCAVTISNPTR-----HVYTG--G---K--G----C-----VKVWDISHPGNKSP---VSQ-LDC-------------LNRDNYIRSCKLLPDGCTLIVGG---EA-----S--T-----------------------------------LSIWDLAAPTPR------------IK------AE-LTS-----------SAPACYALAISPDS---KVCFSCCS---DGN----IAVWDL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31 HHSearch 35.639% -56 - C3 - - 2VDU - TRM82_YEAST D:[104-236] -----------------------------------------------------------------------------------------------------------------------------YIRNLRLTSDES----RLIACAD-S---D--K----S-----LLVFDVDKTSK--NVLKLRK-R--F-------------CFSKRPNAISIAEDDTTVIIAD---KF-----G--D-----------------------------------VYSIDINSIPEEKFT---------QE------PI-L-G-----------HVSMLTDVHLIKDSDGHQFIITSDR-----D----EHIKISHYP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 HHSearch 35.5313% -25 - C3 - - 1GXR - B:[8-172] ------------------GSKPAYSFHV-----MQPVPFP-------------P--------D----ALIGPGI-PRHAR---Q----I--N-------------T--------LN-HG----E-VVCAVTISNPTR-----HVYTG--G---K--G----C-----VKVWDISH---KSP-VSQLD---C-------------LNRDNYIRSCKLLPDGCTLIVGG---EA-----S--T-----------------------------------LSIWDLA---PR--I---------KA------EL-T-S-----------SAPACYALAISPDS---KVCFSCCS---D-G-----NIAVWDL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 HHSearch 34.929% -56 - C3 - - 2VDU - TRM82_YEAST B:[104-238] -----------------------------------------------------------------------------------------------------------------------------YIRNLRLTSDES----RLIACAD-S---D--K----S-----LLVFDVDKTSK--NVLKLRK-R--F-------------CFSKRPNAISIAEDDTTVIIAD---KF-----G--D-----------------------------------VYSIDINSIPEEKFT---------QE------PI-L-G-----------HVSMLTDVHLIKDSDGHQFIITSDR-----D----EHIKISHYP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------