@TOME V2.3
(Mar 2018)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CRKL_HUMAN: (2018-07-12 )
MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE

Atome Classification :

(20 SA) .........10........20........30-.-........40........50.....---...60...-----------------...-----------------.-------.-----------------70...--.-....80........90...--.....100.......110.......120.......130.......140.......150.......160.......170.......180-----........190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
2 PsiBlast_PDB 79.6999% -53 - C1 - - 2LQW - CRKL_HUMAN A:[1-303] MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
31 HHSearch 79.09100% -54 - C1 - - 2LQN - CRKL_HUMAN A:[1-303] MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
21 Fugue 78.90100% -54 - C1 - - 2LQN - CRKL_HUMAN A:[1-303] MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
1 PsiBlast_PDB 78.70100% -54 - C1 - - 2LQN - CRKL_HUMAN A:[1-303] MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
6 PsiBlast_PDB 58.18100%-119 - C1 - - 2EO3 - CRKL_HUMAN A:[8-111] MSSARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 HHSearch 58.0980%-155 - C1 - - 5JN0 - CRK_MOUSE A:[2-98] -------SEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIIN-----------------S---------------------------R-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVAR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 57.96100%-119 - C1 - - 2EO3 - CRKL_HUMAN A:[10-111] --SARFDSSDRSAWYMGPVSRQEAQTRLQG--Q-RHGMFLVRDSSTCPGDYVLSVSENS---RVSHYIIN-----------------SLP-----------------N-------R-----------------RFKIG--D-QEFDHLPALLEFYKIHYLD--TTTLIEPAPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 57.8180%-155 - C1 - - 5JN0 - CRK_MOUSE A:[1-98] ------DSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIIN-----------------S---------------------------R-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVAR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 54.9561% -17 - C1 - - 2EYY - CRK_HUMAN A:[2-189] --AGNFDSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIINSSGPRPPVPPSPAQPPPGVS-----------------P-------S-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSR-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEK---------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 54.2868% -93 - C1 - - 1JU5 - CRK_HUMAN A:[1-109] ------------SWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIIN-----------------SSG-----------------P-------RPPVPPSPAQPPPGVSPSRLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39 HHSearch 52.0139%-135 * C1 * - 2RVF - ? A:[4-103] --GSSGMAEAAAPWYHGPLSRTDAENSLLR--M-PEGTFLVRDSTSSPGDYVLSCSENG---KVTHYKLS-----------------AEE-------------------------G-----------------KIRID--T-HLFDNLDAAITFYMEHELE--YSSLKQPLQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 51.7056% 38 - C1 - - 2EYZ - CRK_HUMAN A:[2-302] --AGNFDSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIINSSGPRPPVPPSPAQPPPGVS-----------------P-------S-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSR-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVNTPLPNL--------------QNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPEED-
10 PsiBlast_PDB 51.5268% -80 - C1 - - 2EYV - CRK_HUMAN A:[6-120] ------DSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIIN-----------------SSG-----------------P-------RPPVPPSPAQPPPGVSPSRLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 HHSearch 51.2776% -80 - C1 - - 2EYV - CRK_HUMAN A:[4-122] ----MGDSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIIN-----------------SSGPRPPVPPSPAQPPPGVSP-------S-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSRSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 HHSearch 50.0137% 2 - C1 - - 3QWX - CED2_CAEEL X:[4-173] ---NGFDPFEWRSFYFPGMSREEAHKLLGEPQV-SIGTFLMRDS-SRPGEYSLTVREADEGNAVCHYLIE-----------------RGE-----------------PKEDGTAAA-----------------GVKIA--N-QSFPDIPALLNHFKMRVLT--EASLLAAYKK------------------PIIEVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNALGTTGLVPANYVQI---------------------------------------------------------------------------------------------------------------------------------
46 HHSearch 47.1033% -82 - C1 - - 2ECD - A:[9-112] ----PVNSLEKHSWYHGPVSRSAAEYLLSS--L-INGSFLVRESESSPGQLSISLRYEG---RVYHYRIN-----------------TTA-----------------D-------G-----------------KVYVT--AESRFSTLAELVHHHSTVADGL-VTTLHYPAPKCN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 47.0861% 4 - C1 - - 2DVJ - CRK_HUMAN A:[2-189] --AGNFDSEERSSWYWGRLSRQEAVALLQG--Q-RHGVFLVRDSSTSPGDYVLSVSENS---RVSHYIINSSGPRPPVPPSPAQPPPGVS-----------------P-------S-----------------RLRIG--D-QEFDSLPALLEFYKIHYLD--TTTLIEPVSR-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEK---------------------------------------------------------------------------------------------------------------------------------
49 HHSearch 46.5127% -86 - C1 - - 2CS0 - HSH2D_HUMAN A:[6-113] -SGGQLAQDGVPEWFHGAISREDAENLLES--Q-PLGSFLIRVSHSHVG-YTLSYKAQS---SCCHFMVK-----------------LLD-----------------D-------G-----------------TFMIPGEK-VAHTSLDALVTFHQQKPIEPRRELLTQPCRQKD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47 HHSearch 44.7134% -58 - C1 - - 3K2M - ABL1_HUMAN A:[2-100] --------LEKHSWYHGPVSRNAAEYLLSS--G-INGSFLVRESESSPGQRSISLRYEG---RVYHYRIN-----------------TAS-----------------D-------G-----------------KLYVS--SESRFNTLAELVHHHSTVADGL-ITTLHYPAPKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 HHSearch 41.9729% -10 - C1 - - 2GSB - A:[6-112] -SGREEDPHEGKIWFHGKISKQEAYNLLMT--VGQVCSFLVRPSDNTPGDYSLYFRTNE---NIQRFKIC-----------------PTP-----------------N-------N-----------------QFMMG--G-RYYNSIGDIIDHYRKEQIVE-GYYLKEPVPMQD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------