@TOME V2.3
(Mar 2018)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : KI21B_HUMAN: (2018-07-13 )
MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPTRGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTLP

Atome Classification :

(27 SA) ........--.10........20........30...--------.----------..-------..40.---------------.--....--------..50........60........70........80........90......-..100..-----.....-------110--.........120.......130.......140.......150.......-160-.........170......-.--180..--.......190.......200.......210.......220.......--230.......240.......250.......260.......270.......280.......290.......300.......310...-....320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630....
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MAGQGDCC--VKVAVRIRPQLSKEKIEGCHICTSVT--------P----------GE-------PQVLL---------------G--KDKA--------FTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTM-GTGFDMA-----TSEEE-------Q----GIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLF-D---STRDPDTRHRRSNIKIHE-D--A--NG--GIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIF--TIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSK-KVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPTRGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTLP
3 PsiBlast_PDB 88.0645% -58 - C2 - - 2XT3 KIF7_HUMAN A:[9-344] ----EEAP--VRVALRVRPLLPKELLHGHQSCLQVE--------P----------GL-------GRVTL---------------G--RDRH--------FGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEA------------DE-------Q----GIVPRAMAEAFKLIDENDLL---------DCLVHVSYLEVYKEEFRDLL-EVGTASRD---------IQLRE-D--E--RG--NVVLCGVKEVDVEGLDEVLSLLEMGNAARHT------HLSSRSHTVF--TVTLKQR---------GRAP--------------LLVSKFHFVDLAGSERVL-------------QINSSLLALGNVISALGDPQR-RGSNIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 85.6452% -4 - C2 - - 3ZFD KIF4_MOUSE A:[10-344] ----------VRVALRCRPLVSKEIKEGCQTCLSFV--------P----------GE-------PQVVV---------------G--NDKS--------FTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSM-GGAY--------TAEQE-------HDSAIGVIPRVIQLLFKEINKK---------SDFEFTLKVSYLEIYNEEILDLL-C---S-----TQ-----INIRE-D--P--KE--GIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIF--TISIEQRK--------------------KNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDD-K-KGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 85.6252% -4 - C2 - - 3ZFC KIF4_MOUSE A:[10-344] ----------VRVALRCRPLVSKEIKEGCQTCLSFV--------P----------GE-------PQVVV---------------G--NDKS--------FTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSM-GGAY--------TAEQE-------HDSAIGVIPRVIQLLFKEINKK---------SDFEFTLKVSYLEIYNEEILDLL-C---S------Q-----INIRE-D--P--KE--GIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIF--TISIEQRK--------------------KNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDD-K-KGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIIN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 HHSearch 82.9735% -62 - C2 - - 3DCB NOD_DROME A:[20-336] ----KLSA--VRIAVREAPYRQFLGRR-EPSVVQFP--------P----------WSD------GKSLI---------------V--DQNE--------FHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGE-----ILPEH-------L----GILPRALGDIFERVTARQEN------NKDAIQVYASFIEIYNEKPFDLL-G---STPHM-----------------P--MV--AARCQRCTCLPLHSQADLHHILELGTRNRRV--------SSRSHAIV--TIHVKSK---------------------------THHSRMNIVDLAGSEGVRRT----------VNINLGLLSINKVVMSMAAG----HTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKAAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 82.5337% -47 - C2 - - 4ATX - KINH_RAT C:[3-329] --DPAECN--IKVMCRFRP-LNESEVNRGDKYVAKF--------Q----------GE-------DTVMI---------------A--S-KP--------YAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKNHTMEGKLHD---------PEG-------M----GIIPRIVQDIFNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLSVHE-D--K--NR--VPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIF--LINVKQENTQTE---------------------QKLSGKLYLVDLAGSE------------------NKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41 HHSearch 80.5340% - - C2 - - 4CK7 KIF11_HUMAN C:[13-365] --EEKGKN--IQVVVRVRPFNLAERKASAHSIVESD--------P----------VR-------KEVSVRTGGLADK-------S--SRKT--------YTFDMVFGASTKQIDVYRSVVAPILDEVIMGYNATIFAYGQTGTGKTFTM-EGERSPNEEYCWEEDPL-------A----GIIPRTLHQIFEKLTDN----------GTEFSVKVSLLEIYNEELFDLL-N---PSSDV-----SERLQMFD-D--PRNKR--GVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVF--SVTIHMKETTI------------------DGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVER----TPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 HHSearch 80.3339% - - C2 - - 5M5I CUT7_SCHPO C:[5-366] ---ENETN--INVVVRVRGRTDQEVRDNSSLAVSTS--------G----------AMG------AELAIQSDPSSM--------L--VTKT--------YAFDKVFGPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTM-SGDLSDSDG---ILSEG-------A----GLIPRALYQLFSSLDNS----------NQEYAVKCSYYELYNEEIRDLL-V---SEEL------RKPARVFE-DTSR--RG--NVVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIF--TITLHRKVSSGMTDET-NSLT-----INNNSDDLLRASKLHMVDLAGSENIGRSGAENKRARETGMINQSLLTLGRVINALVE----KAHHIPYRESKLTRLLQDSLGGKTKTSMIVTVSSTNTNLEETISTLEYAARAKSIRNKPQNNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 80.0537% -43 - C2 - - 1MKJ KINH_HUMAN A:[2-339] -ADLAECN--IKVMCRFRP-LNESEVNRGDKYIAKF--------Q----------GE-------DTVVI---------------A--S-KP--------YAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---------PEG-------M----GIIPRIVQDIFNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLSVHE-D--K--NR--VPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIF--LINVKQENTQTE---------------------QKLSGKLYLVDLAGSEKV------------AKNINKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 79.9237% -22 - C2 - - 4HNA KINH_HUMAN K:[5-337] ----AESN--IKVMCRFRP-LNESEVNRGDKYIAKF--------Q----------GE-------DTVVI---------------A--S-KP--------YAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---------PEG-------M----GIIPRIVQDIFNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLSVHE-D--K--NR--VPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIF--LINVKQENTQTE---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVSVNVELTA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 79.6437% -43 - C2 - - 2VVG ? A:[6-350] ----------IKVIVRCRPLNARETRENALNIIRMD--------E----------AS-------AQVIV---------------D--P-RT--------FTFDAVYDQTSCNYGIFQASFKPLIDAVLEGFNSTIFAYGQTGAGKTWTM-GG-----------NKEE-------P----GAIPNSFKHLFDAI--------NSSSSNQNFLVIGSYLELYNEEIRDLIKN---NTKLP----------LKE-D--K--TR--GIYVDGLSMHRVTTAAELSALMDKGFANR----------SSRSHSIF--MVRIECSEV----EVIR-------------------VGKLNLVDLAGSER---------------KINLSLSALGLVISKLVEGA----THIPYRDSKLTRLLQDSLGGNSKTLMCANISPASTNYDETMSTLRYADRAKQIKNKPRINEDPKDAQI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 79.0837% -42 - C2 - - 3J8X - KINH_HUMAN K:[5-320] ----AESN--IKVMCRFRP-LNESEVNRGDKYIAKF--------Q----------GE-------DTVVI---------------A--S-KP--------YAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---------PEG-------M----GIIPRIVQDIFNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLSVHE-D--K--NR--VPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIF--LINVKQENTQTE---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39 HHSearch 78.9935% -62 - C2 - - 3DC4 NOD_DROME A:[19-339] ---AKLSA--VRIAVREAPYR--------PSVVQFP--------P----------WSD------GKSLI---------------V--DQNE--------FHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGE-----ILPEH-------L----GILPRALGDIFERVTARQEN------NKDAIQVYASFIEIYNEKPFDLL-G---STPHM-----------------P--MV--AARCQRCTCLPLHSQADLHHILELGTRNRR----------SRSHAIV--TIHVKSK---------------------------THHSRMNIVDLAGSEGV-------------VNINLGLLSINKVVMSMAAG----HTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKAAALEH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 78.7737% -21 - C2 - - 3J8Y KINH_HUMAN K:[5-334] ----AESN--IKVMCRFRP-LNESEVNRGDKYIAKF--------Q----------GE-------DTVVI---------------A--S-KP--------YAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---------PEG-------M----GIIPRIVQDIFNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLSVHE-D--K--NR--VPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIF--LINVKQENTQTE---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS----TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVSVNVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 78.6138% -40 - C2 - - 3X2T KIF5C_MOUSE A:[4-334] ---PAECS--IKVMCRFRPLNEAEILRGDKFIPKFK-------------------GE-------ETVVI---------------G--QGKP--------YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD---------PQL-------M----GIIPRIAHDIFDHIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VSK--------TNLAVHE-D--K--NR--VPYVKGCTERFVSSPEEVMDVIDEGKANRHVA---MNEHSSRSHSIF--LINIKQENVETE---------------------KKLSGKLYLVDLAGSEK-----------------NKSLSALGNVISALAEGTK---THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 HHSearch 78.1043% -4 - C2 - - 2VVG ? B:[4-347] ------DN--IKVIVRCRPLNARETRENALNIIRMD--------E----------AS-------AQVIVDPP----------------PRT--------FTFDAVYDQTSCNYGIFQASFKPLIDAVLEGFNSTIFAYGQTGAGKTWTM-GGN-----------KEE-------P----GAIPNSFKHLFDAINSSS--------SNQNFLVIGSYLELYNEEIRDLI-K---NNT---------KLPLKE-D--K--TR--GIYVDGLSMHRVTTAAELSALMDKGFANR----------SSRSHSIF--MVRIECSEVIE--------------------KEVIRVGKLNLVDLAGSER---------------KINLSLSALGLVISKLVEG----ATHIPYRDSKLTRLLQDSLGGNSKTLMCANISPASTNYDETMSTLRYADRAKQIKNKPRINEDPKD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 76.5137% - - C2 - - 4AQV KIF11_HUMAN C:[19-365] ----------IQVVVRVRPFNLAERKASAHSIVESD--------P----------VR-------KEVSVRTGGLADK-------S--SRKT--------YTFDMVFGASTKQIDVYRSVVAPILDEVIMGYNATIFAYGQTGTGKTFTM-EG--ERS-----PNEEYCWEEDPLA----GIIPRTLHQIFEKLTDN----------GTEFSVKVSLLEIYNEELFDLL-N---PSSDVSER-----LQMFD-D--P--RNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI---------------DG-----EELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP----HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 76.3437% - - C2 - - 4AQW - KIF11_HUMAN C:[19-364] ----------IQVVVRVRPFNLAERKASAHSIVESD--------P----------VR-------KEVSVRTGGLADK-------S--SRKT--------YTFDMVFGASTKQIDVYRSVVAPILDEVIMGYNATIFAYGQTGTGKTFTM-EG--ERS-----PNEEYCWEEDPLA----GIIPRTLHQIFEKLTDN----------GTEFSVKVSLLEIYNEELFDLL-N---PSSDVSER-----LQMFD-D--P--RNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI---------------DG-----EELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP----HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 75.9941% 3 - C2 - - 4BN2 KIF15_HUMAN A:[10-358] ----GDA---IKVFVRIRPPAERS----QNLCLSVL--------S----------ST-------SLRLH---------------SNPEPKT--------FTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTM------MG-----PSESDNFSHNL-R----GVIPRSFEYLFSLI----DREK-----GKSFLCKCSFIEIYNEQIYDLL-D---SAS--------AGLYLRE-H--I--KK--GVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVF--TITIESMEKSNE--IVN-----------------IRTSLLNLVDLAGSER---------------NINRSLSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 73.5241% 34 - C2 - - 3B6U KIF3B_HUMAN A:[22-361] -------S--VRVVVRCRPMNGKEKAASYDKVVDVD--------V----------KL-------GQVSV---------------K--NPKGTAHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTM-E---GIR-----GDPEK-------R----GVIPNSFDHIFTHIS----RSQNQ-----QYLVRASYLEIYQEEIRDLL------SKDQTKR-----LELKE-R--P--DT--GVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIF--VITI----ECSE-------------------ENHIRVGKLNLVDLAGSER----------LKEATKINLSLSALGNVISALVD--G----HIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31 HHSearch 73.1638% -16 - C2 - - 3U06 NCD_DROME B:[56-385] ---DLRDN--IRVFCRIRPPLESEENRMC--CTWTY--------H----------DE-------STVELQSIDKSK--------M--GQQI--------FSFDQVFHPLSSQSDIFEM-VSPLIQSALDGYNICIFAYGQTGSGKTYTM-DGV-----------PES-------V----GVIPRTVDLLFDSIRGYRN-------LGWEYEIKATFLEIYNEVLYDLL------------------------------------YVSNITEETVLDPNHLRHLMHTAKMNR--------ERSSRSHAVT--KLELIGRHAE---------------------KQEISVGSINLVDLAGSESP--------------NINRSLSELTNVILALLQ----KQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 72.6937% - - C2 - - 4UY0 KIF5A_HUMAN C:[7-337] -----ECS--IKVLCRFRPLNQAEILRGDKF-IPIF--------Q----------GD-------DSVVI---------------G---GKP--------YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHD---------PQL-------M----GIIPRIARDIFNHIYSMDENL--------EFHIKVSYFEIYLDKIRDLL-D---VTK--------TNLSVHE-D--K--NR--VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIF--LINIKQENMETE---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-S--YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 HHSearch 71.6644% 14 * C2 * - 3LRE KI18A_HUMAN B:[10-355] ------HH--MKVVVRVRPENTKEKAAGFHKVVHVV--------D----------KHILVFD------Q---------------N--KDLK--------FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM-LGSA-----------DE-------P----GVMYLTMLHLYKCMDEIKE--------EKICSTAVSYLEVYNEQIRDLL-V---NS---------GPLAV----------K--GVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVF--QIYLRQQDKTA------------------SINQNVRIAKMSLIDLAGSERA-------------TNINRSLLALGNVINALADSK-------PYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 HHSearch 71.5643% 23 - C2 - - 5OCU KI18A_HUMAN K:[13-368] ------HH--MKVVVRVRPENTKEKAAGFHKVVHVV--------D----------KHILVFDPK------------------------DLK--------FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM-LGS-----------ADE-------P----GVMYLTMLHLYKCMDEIKE--------EKICSTAVSYLEVYNEQIRDLL-V---NS---------GPLAVRE-D--T--QK--GVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVF--QIYLRQQDKTAS------------------INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR-KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 HHSearch 70.6642% 13 - C2 - - 5GSZ KIF19_MOUSE A:[11-342] -------Q--LMVALRVRPISVAELEEGATLIAHKM--------D----------E--------QMVVLMDPMEDPDDILRAHRS--REKS--------YLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTM-LGT-----------DHE-------P----GIYVRTLNDLFRAIEETS--------NDMEYEVSMSYLEIYNEMIRDLL-N---PAL--------GYLELRE-D--S------VIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPT---QTSSRSHAVL--QVAVRQRSRVK------------------NILQEVRQGRLFMIDLAGSE---------------------LLALGNCINALSDKG--SNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASTAFEESRNTLTYAGR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 HHSearch 67.9438% 16 - C2 - - 3L1C NCD_DROME A:[53-380] ---DLRGN--IRVFCRIRPPLESEENRMC--CTWTY--------H----------DE-------STVELQSIDA-------------GQQI--------FSFDQVFHPLSSQSDIFEM-VSPLIQSALDGYNICIFAYGQSGSGKTYTM-DGV-----------PES-------V----GVIPRTVDLLFDSIRGYRN-------LGWEYEIKATFLEIYNEVLYDLL-S---NEQK------DMEIRMAK-N--N--KN--DIYVSNITEETVLDPNHLRHLMHTAKMN------------SRSHAVT--KLELIGRHAE---------------------KQEISVGSINLVDLAGSESPK----TS-------NINRSLSELTNVILALLQ----KQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 HHSearch 66.0432% 18 - C2 - - 5WDH KIFC1_HUMAN A:[22-376] ------GN--IRVFCRVRPVLPGEPTPPPGLLLFPS---------DPPTRLSLSR---------------------------------RHD--------FSFDRVFPPGSGQDEVFEEI-AMLVQSALDGYPVCIFAYGQTGSGKTFTM-EGGPG-------GDPQL-------E----GLIPRALRHLFSVAQELSG-------QGWTYSFVASYVEIYNETVRDLL-A---TG----------ECEIRRA-------E--ELTVTNARYVPVSCEKEVDALLHLARQNRAVART----RSSRSHSVF--QLQISGEHSS---------------------RGLQCGAPLSLVDLAGSER-------------------SLSTLGLVIMALSN----KESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 62.7737% 39 - C2 - - 5OCU KI18A_HUMAN K:[13-368] --------HHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDP----------K--------------------------------DLK--------FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM-------L-----GSADE-------P----GVMYLTMLHLYKCMDEIK----EEKICS----TAVSYLEVYNEQIRDLL-V---NS---------GPLAVRE-D--T--QK--GVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVF--QIYLRQQDKTAS---INQNVR---------------IAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR-KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------