@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : KLHL7_HUMAN: (2018-07-13 )
MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.-----..----...---.310....---...320.......330.......340.----...-.-----.-----.350.....---..360........370.......380.-......390-........400.......410.......420.......430.......440.......450.......460.......470.......480.......490--.......500.......510.......520.......530.......540.......550.......560.......570.......580....
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQP-----QS----CRY---FNPKDYSW---TDIRCPFEKRRDAACVFWDNVVYILGG----SQL-F-----P-----IKRMDCYNV---VKDS-WYSKLGPPTPRDSLAACAAEGK-IYTSGGSE--VGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGL--GGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
21 HHSearch 89.05100%-123 - C1 - - 3II7 KLHL7_HUMAN A:[10-297] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHDYRIALFGGSQP-----QS----CRY---FNPKDYSW---TDIRCPFEKRRDAACVFWDNVVYILGG----SQL-F-----P-----IKRMDCYNV---VKDS-WYSKLGPPTPRDSLAACAAEGK-IYTSGGSE--VGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGL--GGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTC---------
1 PsiBlast_PDB 89.05100%-123 - C1 - - 3II7 KLHL7_HUMAN A:[10-297] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHDYRIALFGGSQP-----QS----CRY---FNPKDYSW---TDIRCPFEKRRDAACVFWDNVVYILGG----SQL-F-----P-----IKRMDCYNV---VKDS-WYSKLGPPTPRDSLAACAAEGK-IYTSGGSE--VGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGL--GGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTC---------
6 PsiBlast_PDB 66.5932% -37 - C1 - - 2VPJ - KLH12_HUMAN A:[13-281] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANEVLLVVGGFGSQ-----QSPIDVVEK---YDPKTQEW---SFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRL-S-----S-----VECLD-YTA---DEDGVWYS-VAPMNVRRGLAGATTLGDMIYVSGGFD---GSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNI----LNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGT--AHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSW-------------------------------
10 PsiBlast_PDB 62.1530% -29 - C1 - - 2DYH - A:[21-284] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
20 PsiBlast_PDB 62.0530% -29 - C1 - - 5FNQ A:[8-271] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
18 PsiBlast_PDB 61.7330% -1 - C1 - - 4L7D KEAP1_HUMAN A:[11-274] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSDGTW---LDLADLQVPRSGLAGCVVGGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCAPMSVPRNRIGVGVIDGH-IYAVGGSH---GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTW-------------------------------
8 PsiBlast_PDB 61.7030% -27 - C1 - - 1X2J - A:[20-283] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
14 PsiBlast_PDB 61.6330% -33 - C1 - - 3WN7 - KEAP1_MOUSE A:[30-293] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
17 PsiBlast_PDB 61.3230% -3 - C1 - - 4L7C - KEAP1_HUMAN A:[11-274] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSDGTW---LDLADLQVPRSGLAGCVVGGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCAPMSVPRNRIGVGVIDGH-IYAVGGSH---GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTW-------------------------------
11 PsiBlast_PDB 61.3230% -29 - C1 - - 2Z32 - A:[21-284] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
9 PsiBlast_PDB 61.1330% -28 - C1 - - 1X2R - A:[20-283] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
12 PsiBlast_PDB 60.8630% -31 - C1 - - 3ADE - A:[21-284] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
7 PsiBlast_PDB 60.8630% -30 - C1 - - 5CGJ A:[40-303] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
15 PsiBlast_PDB 60.6330% -32 - C1 - - 4ZY3 KEAP1_MOUSE A:[30-293] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
27 HHSearch 60.5029% -26 - C1 - - 2VPJ - KLH12_HUMAN A:[13-297] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANEVLLVVGGFGSQQSPIDV----VEK---YDPKTQEW---SFLPSITRKRRYVASVSLHDRIYVIGG----YDGRS-----R-----LSSVECLDYTADEDGV-WYSVAPMNVRRGLAGATTLGDM-IYVSGGFD--GS-RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLN----ILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGT--AHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVC---------------
13 PsiBlast_PDB 60.1530% -29 - C1 - - 3WDZ - A:[30-293] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSNGSWLRLADLQVP--RSGLAGCVV-GGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCASMSVPRNRIGVGVIDGH-IYAVGGSHGCIHHSSV---ERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTW-------------------------------
19 PsiBlast_PDB 59.3330% -4 - C1 - - 4N1B KEAP1_HUMAN A:[11-274] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSDGTW---LDLADLQVPRSGLAGCVVGGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCAPMSVPRNRIGVGVIDGH-IYAVGGSH---GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTW-------------------------------
16 PsiBlast_PDB 59.2430% 0 - C1 - - 4L7B KEAP1_HUMAN A:[11-274] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTAGGYFR-----QS----LSYLEAYNPSDGTW---LDLADLQVPRSGLAGCVVGGLLYAVGG----RNN-S-----PDGNTDSSALDCYNP---MTNQ-WSPCAPMSVPRNRIGVGVIDGH-IYAVGGSH---GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNR----LNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTW-------------------------------
24 HHSearch 58.8127% -3 - C1 - - 4IFJ - KEAP1_HUMAN A:[325-605] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GRLIYTAGGYFRQSL--SY----LEA---YNPSDGTW---LRLADLQVPRSGLAGCVVGGLLYAVGG----RNN-SPDGNTD-----SSALDCYNP---MTNQ-WSPCAPMSVPRNRIGVGVIDGH-IYAVGGSH--GC-IHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTN----RLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQ--DQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVG-----------------
39 HHSearch 58.1026% -69 - C1 - - 5NKP - B:[3-233] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPKVMIVVGG----QAP-K-----A-----IRSVECYDF---EEDR-WDQIAELPSRRCRAGVVFMAGH-VYAVGGFN--GS-LRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGST----GLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRR--------------------