@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VL50: (2017-10-31 )
MMLADPSKKYRRMYQRVDLPDRQWPNNEITKAPIWMSTDLRDGNQAIFEPMNMEQKFKMFKMLVKIGFKHIEIGFPSASQIDFDFTRMLIEENHIPDDVYIEVLVQARDHLIERTFEALAGAKRAIVHIYNSNSPTFRQKVLNVDVNGAKQLAVNAAQKVKEYAAQYPETDWIFQYSPECFSATELEVAKEVCDAVTEIWDARPDHKVILNLPATVEVSTPNVYADQIEWMHRNLARRDGVIISVHCHNDRGCGIAASELAIMAGADRVEGCVFGNGERTGNVDVAAIALNMYTQGVAPELDFSNINEVIATVEECTGLPVHPRHPYAGDLVFTAFSGSHQDAIKKGFEYQKNEEIWDMPYLPIDPKDLGRDYDAVIRVNSQSGKGGIAYLLESNYNVVLPRRLQIEFSQVVQQYTDENGTEISAKQIWTLFKDTYVEVKNHHYTVKNYKLSDINGTQIIELEIDVEGETQQLRGEGNGPISAFLNALQLPIDVLNYEERSISSGANAKALTLIELQVKGTGRGSFGAGVHDNTVTSSIEAIIACTNRLIDQGVLSTDQVVAAAV
Atome Classification :
(20 SA)
------------------.....-....10...----....---.20........30........40........50..-......60......-...70........80........90........100.......110.......120.......130.......140.......150--.........160.......170.......180.......190.......------200......-.210......-.220.......230........240.......250.......260.......270.......280.......290...---....300.......310.......320.......330.......340.....----------..--350----------..-------.-....360.......370.......380-.......390........400.......410.......420.....-..430.......440.......--450....-...460.......470.......480.......---490.......500---.......510.......520.......530.......540.......550.......560...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------MMLAD-P
S
K
K
Y
R
R
M
Y
----
Q
RVD---LPDRQWPNNEITKA
P
I
W
M
STDLRDG
N
Q
A
IFEPM
N
M
-
E
Q
K
F
K
M
F
-
K
M
L
V
K
I-GF
K
H
I
E
IGFPSASQI
D
F
D
F
T
R
M
L
I
EENHIP
D
D
V
Y
I
E
V
L
V
Q
A
R
D
H
L
I
E
R
T
F
E
A
L
AGA
K
R
A
I
V
H
I
YNSNS
P
T
F
R
Q
K
V
L
N
VDVNG
A
K
----
Q
L
A
V
N
A
A
Q
K
V
K
E
Y
A
A
QYPET
D
W
I
F
Q
YSPECF
S
A
T
E
L
E
V
A
K
E
V
C
D
A
V
T
E
I
------WDARPD
H
K
V
-
I
L
NLP
A
T
V
E
V-STPN
V
Y
A
D
Q
I
E
W
-
M
H
R
N
LARRD
G
V
I
I
S
V
H
CHNDRGCG
I
A
A
S
E
L
A
I
MAGADRV
E
G
C
V
FGNGERTGN
V
D
V
A
A
I
A
L
N
M
YTQ---GVAPEL
D
F
S
N
I
N
E
V
I
A
T
V
E
E
CTGLPVHPRHPYAG
D
L
V
F
T
AFSGS
H
Q
D
A
I
K
KG----------FE--YQK----------NE-------E-IWDMPYLPI
D
P
K
D
LGRDY
D
A
V
I
R
V
NSQ-SGKG
G
I
A
Y
L
-
L
ESN
Y
N
V
V
LP
R
R
L
Q
I
E
F
S
Q
V
V
Q
Q
Y
TDENG
T
E
I
S
A
K
Q
-
I
W
T
L
F
K
D
T
Y
V
E
V
KN
H
H
Y
T
V
K
N
Y
--
K
LSDING-
T
Q
I
I
E
L
E
I
D
VEG
E
T
Q
Q
LRGEGN
G
P
I
S
A
F
L
N
A
L
Q---L
P
I
D
VLNY
E
E
RSI---SSGAN
A
K
A
L
T
L
I
E
L
Q
V
K
GTGRGSFGAGVHDN
T
V
T
S
S
I
E
A
I
I
A
C
T
N
R
L
I
D
QGVLSTD
Q
V
V
AAAV
24
PsiBlast_CBE
99.03
50%
0
- C- -
-
3FIG
4
LEU1_MYCTU
B:
[44-612]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
R
V
N
-----
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
--------
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
22
PsiBlast_CBE
99.03
50%
0
- C- -
-
3HPZ
3
LEU1_MYCTU
B:
[42-610]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
P
I
R
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
R
V
N
-----
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
--------
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
21
PsiBlast_CBE
99.03
50%
0
- C- -
-
3HQ1
3
LEU1_MYCTU
B:
[42-610]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
P
I
R
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
R
V
N
-----
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
--------
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
23
PsiBlast_CBE
98.15
50%
0
- C- -
-
3HPS
5
LEU1_MYCTU
B:
[42-609]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PI-
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
R
V
N
-----
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
--------
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
4
PsiBlast_PDB
97.48
50%
0
- C- -
-
3FIG
4
LEU1_MYCTU
A:
[44-613]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
--------
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
I
------
E
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
3
PsiBlast_PDB
97.48
50%
0
- C- -
-
3HQ1
3
LEU1_MYCTU
A:
[42-612]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
--------
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
I
------
E
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
1
PsiBlast_PDB
97.48
50%
0
- C- -
-
3HPS
5
LEU1_MYCTU
A:
[42-610]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
--------
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
I
------
E
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
2
PsiBlast_PDB
97.06
50%
0
- C- -
-
3HPZ
2
LEU1_MYCTU
A:
[42-612]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
---------
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
-------
E
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
5
PsiBlast_PDB
96.81
50%
0
- C- -
-
1SR9
1
LEU1_MYCTU
A:
[42-612]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
L
D
A
M
K
L
D
A
D
A
A
D
--
C
D
V
----------
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
I
--------
K
G
G
V
A
Y
I
-
M
K
T
D
H
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
I
------
E
V
S
P
K
E
-
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
D
A
A
D
D
D
G
G
-
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
DVG
F
D
V
A
V
L
D
Y
Y
E
H
A
M
---
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
-----------------------------------------------
50
Fugue
78.74
47%
17
- C3 -
-
1SR9
1
LEU1_MYCTU
A:
[18-643]
TIVKPAGPPRVGQPSWNP
Q
R
A
S
S
M
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
---
A
L
I
D
P
M
S
P
A
R
K
R
R
M
F
D
L
L
V
R
M
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
-
E
M
T
T
P
N
V
Y
A
D
S
I
E
W
M
S
-
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
A
M
K
L
D
----------
A
D
A
A
DCDVD
D
M
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
-------
Y
E
A
-
V
I
K
G
G
V
A
Y
I
M
K
T
D
H
-
G
L
S
L
P
R
R
L
Q
I
E
F
S
Q
V
I
Q
K
------
I
E
V
S
P
K
E
M
W
D
A
F
A
E
E
Y
L
A
P
V
R
P
L
E
R
I
R
Q
H
V
--
D
A
A
D
D
D
G
G
T
T
S
I
T
A
T
V
K
I
N
G
V
E
T
E
I
S
G
S
G
N
G
P
L
A
A
F
V
H
A
L
A
---
D
V
G
F
D
V
A
V
L
D
Y
Y
E
H
A
M
S
A
G
D
D
A
Q
A
A
A
Y
V
E
A
S
V
T
I
-
S
K
T
V
W
G
V
G
I
A
P
S
I
T
T
A
S
L
R
A
V
V
S
A
V
N
R
A
A
---------------
7
PsiBlast_PDB
72.09
55%
16
- C3 -
-
3HPX
2
LEU1_MYCTU
A:
[42-425]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
71.79
56%
-5
- C3 -
-
3HPX
2
LEU1_MYCTU
B:
[39-423]
--------------------
S
S
M
-
P
V
N
R
Y
R
P
-
F
AEEV
E
P
I
R
---
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
----
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
I
APTPE
R
P
------
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
71.27
55%
15
- C3 -
-
3HPX
2
LEU1_MYCTU
B:
[42-425]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
D
A
A
DCDV
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
70.92
55%
13
- C3 -
-
3U6W
3
LEU1_MYCTU
A:
[44-427]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
DV--------
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
70.60
55%
16
- C3 -
-
3U6W
3
LEU1_MYCTU
B:
[44-427]
------------------------
P
V
N
R
Y
R
P
F
A
----
E
E
V
E
PIR
L
R
N
R
T
W
P
D
R
V
I
D
R
A
P
L
W
C
A
V
D
L
R
D
G
N
Q
A
L
I
D
P
M
S
P
-
A
R
K
R
R
M
F
-
D
L
L
V
R
M
-
G
Y
K
E
I
E
V
G
F
P
S
A
S
Q
T
D
F
D
F
V
R
E
I
I
E
Q
G
A
I
P
D
D
V
T
I
Q
V
L
T
Q
C
R
P
E
L
I
E
R
T
F
Q
A
C
S
G
A
P
R
A
I
V
H
F
Y
N
S
T
S
I
L
Q
R
R
V
V
F
R
A
N
R
A
E
V
Q
----
A
I
A
T
D
G
A
R
K
C
V
E
Q
A
A
K
Y
P
G
T
Q
W
R
F
E
Y
S
P
E
S
Y
T
G
T
E
L
E
Y
A
K
Q
V
C
D
A
V
G
E
V
------
I
A
P
T
P
E
R
P
I
-
I
F
N
L
P
A
T
V
E
M
-
T
T
P
N
V
Y
A
D
S
I
E
W
-
M
S
R
N
L
A
N
R
E
S
V
I
L
S
L
H
P
H
N
D
R
G
T
A
V
A
A
A
E
L
G
F
A
A
G
A
D
R
I
E
G
C
L
F
G
N
G
E
R
T
G
N
V
C
L
V
T
L
G
L
N
L
F
S
R
---
G
V
D
P
Q
I
D
F
S
N
I
D
E
I
R
R
T
V
E
Y
C
N
Q
L
P
V
H
E
R
H
P
Y
G
G
D
L
V
Y
T
A
F
S
G
S
H
Q
D
A
I
N
K
G
----------
L
D
--
A
M
K
L
D
A
DCDV---
D
D
-------
M
-
L
W
Q
V
P
Y
L
P
I
D
P
R
D
V
G
R
T
Y
E
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.71
28%
-94
- C3 -
-
4OV9
1
?
A:
[33-406]
-----------------------------------------------------------------
L
R
D
G
N
Q
A
L
K
R
P
W
T
I
-
D
E
K
I
E
V
F
-
D
L
L
V
E
L
-
N
V
D
G
I
E
V
G
F
P
S
S
N
E
T
E
F
H
T
C
Q
V
L
--
S
K
R
A
P
K
G
K
P
I
A
A
L
S
R
A
N
Q
N
E
I
A
V
T
W
E
A
I
Q
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
L
----
Q
K
I
R
N
S
I
S
F
A
R
S
I
V
G
P
G
I
E
----
I
Q
F
S
G
E
H
F
-
G
D
A
I
E
N
F
A
F
T
K
E
A
F
L
T
A
------
I
E
A
G
A
N
----
I
I
N
L
P
N
T
V
E
R
-
Y
R
P
M
V
F
V
N
M
V
K
E
-
I
K
D
V
V
--
K
D
K
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
R
A
G
N
T
N
L
Y
E
T
A
I
A
L
H
Q
N
---
G
E
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
H
Q
-----
T
----------
L
H
--
Q
S
K
----------
G
--------------
A
Y
R
T
F
S
P
E
F
V
G
R
M
D
K
E
T
I
S
F
T
N
Q
-
S
G
H
K
A
I
E
F
L
-
L
H
Q
R
G
I
Q
V
S
K
E
G
I
H
H
L
F
S
L
A
K
S
I
S
S
R
E
N
N
R
E
I
T
E
A
E
-
L
V
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
63.18
28%
-94
- C3 -
-
4OV4
1
?
A:
[33-406]
-----------------------------------------------------------------
L
R
D
G
N
Q
A
L
K
R
P
W
T
I
-
D
E
K
I
E
V
F
-
D
L
L
V
E
L
-
N
V
D
G
I
E
V
G
F
P
S
S
N
E
T
E
F
H
T
C
Q
V
L
--
S
K
R
A
P
K
G
K
P
I
A
A
L
S
R
A
N
Q
N
E
I
A
V
T
W
E
A
I
Q
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
L
----
Q
K
I
R
N
S
I
S
F
A
R
S
I
V
G
P
G
I
E
----
I
Q
F
S
G
E
H
F
-
G
D
A
I
E
N
F
A
F
T
K
E
A
F
L
T
A
------
I
E
A
G
A
N
----
I
I
N
L
P
N
T
V
E
R
-
Y
R
P
M
V
F
V
N
M
V
K
E
-
I
K
D
V
V
--
K
D
K
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
R
A
G
N
T
N
L
Y
E
T
A
I
A
L
H
Q
N
---
G
E
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
H
Q
-----------------
H
--
Q
S
K
----------
G
--------------
A
Y
R
T
F
S
P
E
F
V
G
R
M
D
K
E
T
I
S
F
T
N
Q
-
S
G
H
K
A
I
E
F
L
-
L
H
Q
R
G
I
Q
V
S
K
E
G
I
H
H
L
F
S
L
A
K
S
I
S
S
R
E
N
N
R
E
I
T
E
A
E
-
L
V
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
60.47
21%
-87
- C3 -
-
3IVT
1
HOSM_SCHPO
B:
[37-410]
-------------------------------------------------------
V
N
N
F
S
I
I
E
S
T
L
R
E
G
E
Q
F
A
N
A
F
F
D
T
-
E
K
K
I
Q
I
A
-
K
A
L
D
N
F
-
G
V
D
Y
I
E
L
T
S
P
V
A
S
E
Q
S
R
Q
D
C
E
A
I
C
K
L
G
L
---
K
C
K
I
L
T
H
I
R
C
H
M
D
D
A
R
V
A
V
E
T
--
G
V
D
--
G
V
D
V
V
I
G
T
S
Q
Y
L
R
K
Y
S
H
G
K
D
M
T
Y
I
I
----
D
S
A
T
E
V
I
N
F
V
K
S
K
-------
G
I
E
V
R
F
S
S
E
D
S
F
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
------
N
-
R
V
G
I
A
D
T
V
G
C
-
A
T
P
R
Q
V
Y
D
L
I
R
T
-
L
R
G
V
V
----
S
C
D
I
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
D
R
E
Y
I
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
H
A
K
A
I
L
A
N
----------------------------------------
P
S
T
Y
E
I
L
K
P
E
D
F
G
M
S
R
--
Y
V
H
V
G
S
R
L
T
G
W
N
A
I
K
S
R
-
A
-
E
Q
L
N
L
H
L
T
D
A
Q
A
K
E
L
T
V
R
I
K
K
L
A
D
V
R
-
T
-
L
A
M
D
D
-
V
D
R
V
L
R
E
Y
H
A
D
----------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
59.35
21%
-89
- C3 -
-
3IVS
-
HOSM_SCHPO
B:
[37-409]
-------------------------------------------------------
V
N
N
F
S
I
I
E
S
T
L
R
E
G
E
Q
F
A
N
A
F
F
D
T
-
E
K
K
I
Q
I
A
-
K
A
L
D
N
F
-
G
V
D
Y
I
E
L
T
S
P
V
A
S
E
Q
S
R
Q
D
C
E
A
I
C
K
L
G
L
---
K
C
K
I
L
T
H
I
R
C
H
M
D
D
A
R
V
A
V
E
T
--
G
V
D
--
G
V
D
V
V
I
G
T
-------------
T
Y
I
I
----
D
S
A
T
E
V
I
N
F
V
K
S
K
-------
G
I
E
V
R
F
S
S
E
D
S
F
R
S
D
L
V
D
L
L
S
L
Y
K
A
V
D
K
I
------
G
V
------
N
-
R
V
G
I
A
D
T
V
G
C
-
A
T
P
R
Q
V
Y
D
L
I
R
T
-
L
R
G
V
V
----
S
C
D
I
E
C
H
F
H
N
D
T
G
M
A
I
A
N
A
Y
C
A
L
E
A
G
A
T
H
I
D
T
S
I
L
G
I
G
E
R
N
G
I
T
P
L
G
A
L
L
A
R
M
Y
V
T
DRE
Y
I
T
H
K
Y
K
L
N
Q
L
R
E
L
E
N
L
V
A
D
A
V
E
V
Q
I
P
F
N
N
Y
I
T
G
M
C
A
F
T
H
K
A
G
I
H
A
K
A
I
L
A
N
----------------------------------------
P
S
T
Y
E
I
L
K
P
E
D
F
G
M
S
R
--
Y
V
H
V
G
S
R
L
T
G
W
N
A
I
K
S
R
-
A
-
E
Q
L
N
L
H
L
---
Q
A
K
E
L
T
V
R
I
K
K
L
A
--------
M
D
D
-
V
D
R
V
L
R
E
Y
H
A
-----------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
56.91
28%
-37
- C3 -
-
4OV4
1
?
A:
[23-408]
-------------------------------------------------------
P
K
T
I
H
I
Q
D
V
T
L
R
D
G
N
Q
A
L
K
R
P
W
T
I
-
D
E
K
I
E
V
F
-
D
L
L
V
E
L
-
N
V
D
G
I
E
V
G
F
P
S
S
N
E
T
E
F
H
T
C
Q
V
L
S
K
R
--
A
P
K
G
K
P
I
A
A
L
S
R
A
N
Q
N
E
I
A
V
T
W
E
A
I
Q
K
A
D
C
P
R
M
H
I
V
Y
P
V
S
D
F
S
I
K
H
V
L
K
I
S
E
K
E
V
L
----
Q
K
I
R
N
S
I
S
F
A
R
S
I
V
----
G
P
G
I
E
I
Q
F
S
G
E
H
F
G
D
-----
A
I
E
N
F
A
F
T
K
E
A
------
F
L
T
A
I
E
A
G
A
N
I
I
N
L
P
N
T
V
E
R
-
Y
R
P
M
V
F
V
N
M
V
K
E
-
I
K
D
V
V
--
K
D
K
A
I
I
S
I
H
T
H
N
D
L
G
M
A
T
A
T
S
V
E
S
V
Y
V
G
A
E
Q
I
E
V
A
L
N
G
L
G
E
R
A
G
N
T
N
L
Y
E
T
A
I
A
L
H
Q
N
---
G
E
N
L
N
I
N
F
Q
R
I
Y
P
T
A
K
R
I
S
E
L
T
G
I
P
I
G
E
K
T
P
I
I
G
E
D
I
F
S
H
R
S
G
I
H
Q
H
Q
S
K
G
A
-------------------------------------------
Y
R
T
F
S
P
E
F
V
G
R
M
D
K
E
T
I
S
F
T
N
Q
-
S
G
H
K
A
I
E
F
L
-
L
H
Q
R
G
I
Q
V
S
K
E
G
I
H
H
L
F
S
L
A
K
S
I
S
S
R
E
N
N
R
E
I
T
E
A
E
-
L
V
A
L
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------