@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VL96: (2017-11-01 )
MSQKQPYTPGEFQWSFLLPKYWGVWIAITFLMLLAILPWAIQWRLAHGLANLAWKYLKSRRKTTIRNLEVCFPEWSPEKVQQQAKQVFVDMMLGIFETLNAWYKPYWFKNRVTIEGLEHITNAQAQGKGVLLLGTHSTLLDAGGYVCAQYFEPDVVYRPQNNPLLDMLIYRCRGTIYKAQIDHDDMRGLIRHLKEGDAIWYSPDQDFGLKQGVMAPFFGVPAATVTAHRRLLKISKAVAVPLYFYRHGNVQNPKYHILIEPAVDNLPSEDEVDDATRVNKIIENQLRIAPTQYMWFHRRFKTRPEGYEEIY
Atome Classification :
(19 SA)
---------------------------------------------------------------------------------------------------------------------------------------.........--------10........20.......------.-----30........------------40........50......-..60.....-...70........80-........90-----------.....---....100.--.-..-...110..-......---.120......-----.130-..--------------------..-....140..-----..--------.-.-.150-----....-----.---..-----------------------------..160...---.---....--------.--170-.--.---......180--..-------.----...-..190..-.-------..------.-------.200.......210.......220.......----230......--.240-----......---.-250--------.........260.......------270....--..-.280----------------.........290......---.300.......310--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------MSQKQPYTP--------G
E
F
Q
W
S
FLL
P
K
Y
W
G
V
W
I
A
I
------
T
-----
F
L
M
L
L
A
I
L
P
W
------------
A
I
Q
W
R
L
A
H
G
L
A
N
L
A
W
K
Y
L
-
K
S
R
R
K
T
TIR-N
L
E
V
CFPEW
S
P
E
K
V
Q
-
Q
Q
A
K
Q
V
F
V
D
------------
M
M
L
G
I
---
F
E
T
L
N
A
W
Y--K-P
Y
-
W
FK
N
--
R
V
-
T
I
E
G
L
E
---
H
I
TNAQAQGK-----
G
V
L
--
L
L--------------------GT-H
S
T
L
LDAG
G
-----
Y
V
--------
C
-
A
-
Q
Y-------FEP
D
-----
V
---
V
Y-----------------------------RPQ--NN
P
---
L
---
L
D
M
L
--------
I
--
Y
R
--C--R---G
T
I
Y
K
A
Q-I--
D
H
-------
D
----
D
M
R
-
G
L
I
R
H
L
K-E-------G
D
------
A
-------
I
W
YSPDQDFGLKQGVMAPFFGVP
A
A
T
V
T
A
H
R
----
R
L
L
K
I
S
K
A
V
--
A
V
P
L
-----
Y
F
Y
RHG---N-V----------QN
P
K
Y
H
I
L
IEPAVDNLPSE------DEV
D
D
A
T
--
R
V
-
N
K
------------------
I
I
E
N
QLRIAP
T
Q
Y
M
W
F
H
R
---
R
FKTRPEGYEEIY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
72.08
28%
20
- C6 -
-
5KNK
6
?
B:
[34-300]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
R
L
L
A
G
L
V
N
T
L
K
-
I
T
R
T
S
K
S
I
E
L
N
L
R
I
A
L
P
Y
L
T
P
Q
Q
R
I
-
A
I
T
E
K
A
V
R
N
------------
E
L
T
S
Y
---
F
E
F
L
S
I
W
G
--
S
-
S
N
-
S
-
K
N
IS
R
I
H
R
I
E
G
E
H
---
F
F
H
E
A
L
A
A
K
K
-----
G
V
V
--
L
I
--------------------
V
P
-
H
F
G
T
W
A
V
M
N
-----
A
W
--------
C
-
A
-
Q
F
-------
T
S
M
T
-----
I
---
L
Y
-----------------------------
K
P
V
--
K
N
A
---
D
---
A
D
R
F
--------
V
RE
A
R
--
S
--
R
---
E
Q
A
N
L
V
P
-
T
--
D
E
-------
S
----
G
V
R
-
Q
I
F
K
A
L
K
-
Q
-------
G
E
------
T
-------
T
V
I
L
P
D
H
T
P
N
V
G
-
G
D
M
V
N
Y
F
G
V
P
L
A
S
S
N
L
S
A
----
K
L
I
Q
K
T
K
A
K
--
A
L
F
L
-----
Y
A
I
R
N
-----------------
E
N
D
G
F
T
M
H
I
E
P
-
M
D
E
K
I
Y
E
------
G
T
A
D
D
G
T
--
Y
V
I
H
Q
------------------
A
I
E
Q
L
I
Y
Q
Y
P
E
H
Y
H
W
S
Y
K
---
R
F
K
A
N
P
-
A
L
D
N
I
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
70.81
25%
11
- C6 -
-
5KNK
6
?
B:
[10-333]
-----------------------------------------------------------------------------------------------------------------------------------------------
P
--------
D
S
K
S
M
N
Y
Q
L
L
K
T
F
S
R
Q
-----------------------
P
I
------------
Q
F
G
R
F
L
A
R
L
L
A
G
L
V
N
T
L
K
-
I
T
R
T
S
K
S
I
E
L
N
L
R
I
A
L
P
Y
L
T
P
Q
Q
R
I
-
A
I
T
E
K
A
V
R
N
------------
E
L
T
S
Y
---
F
E
F
L
S
I
W
G
SS
N
-
S
K
-
N
I
S
R
--
I
H
-
R
I
E
G
E
H
---
F
F
H
E
A
L
A
A
K
K
-----
G
V
V
--
L
I
--------------------
V
P
-
H
F
G
T
W
A
V
M
N
-----
A
W
--------
C
-
A
-
Q
F
-------
T
S
M
T
-----
I
---
L
Y
-----------------------------
K
P
V
--
K
N
A
---
D
---
A
D
R
F
--------
V
--
R
E
--
A
--
R
---
S
R
E
Q
A
N
L
-
V
PT
D
E
-------
S
----
G
V
R
-
Q
I
F
K
A
L
K
-
Q
-------
G
E
------
T
-------
T
V
I
L
P
D
H
-
T
P
N
V
G
G
D
M
V
N
Y
F
G
V
P
L
A
S
S
N
L
S
A
----
K
L
I
Q
K
T
K
A
K
--
A
L
F
L
-----
Y
A
I
R
N
-----------------
E
N
D
G
F
T
M
H
I
E
P
M
D
E
K
I
Y
E
G
------
T
A
D
D
G
T
Y
--
V
I
-
H
Q
------------------
A
I
E
Q
L
I
Y
Q
Y
P
E
H
Y
H
W
S
Y
K
---
R
F
K
A
N
P
A
-
L
D
N
I
Y
NIDPTEALKIVDRLKAEALKTSTQPEPIQTSVM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
69.19
28%
27
- C6 -
-
5KN7
8
?
B:
[34-294]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
R
L
L
A
G
L
V
N
T
L
K
-
I
T
R
T
S
K
S
I
E
L
N
L
R
I
A
L
P
Y
L
T
P
Q
Q
R
I
-
A
I
T
E
K
A
V
R
N
------------
E
L
T
S
Y
---
F
E
F
L
S
I
W
G
--
S
-
S
N
-
S
-
K
N
IS
R
I
H
R
I
E
G
E
H
---
F
F
H
E
A
L
A
A
K
K
-----
G
V
V
--
L
I
--------------------
V
P
-
H
F
G
T
W
E
V
M
N
-----
A
W
--------
C
-
A
-
Q
F
-------
T
S
M
T
-----
I
---
L
Y
-----------------------------
K
P
V
--
K
N
A
---
D
---
A
D
R
F
--------
V
RE
A
R
--
S
--
R
---
E
Q
A
N
L
V
P
-
T
--
D
E
-------
S
----
G
V
R
-
Q
I
F
K
A
L
K
-
Q
-------
G
E
------
T
-------
T
V
I
L
P
D
H
T
P
N
V
G
-
G
D
M
V
N
Y
F
G
V
P
L
A
S
S
N
L
S
A
----
K
L
I
Q
K
T
K
A
K
--
A
L
F
L
-----
Y
A
I
R
N
-----------------
E
N
D
G
F
T
M
H
I
E
P
-
M
D
E
K
I
Y
E
------
G
T
A
D
D
G
T
--
Y
V
I
H
Q
------------------
A
I
E
Q
L
I
Y
Q
Y
P
E
H
Y
H
W
S
Y
K
---
R
F
K
A
N
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
66.76
24%
8
- C6 -
-
5KNK
6
?
B:
[15-297]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
Y
------
Q
-----
L
L
K
T
F
S
R
Q
P
I
------------
Q
F
G
R
F
L
A
R
L
L
A
G
L
V
N
T
L
K
I
T
R
T
S
K
S
I
E
L
-
N
L
R
I
A
L
P
Y
L
T
P
Q
Q
R
I
-
A
I
T
E
K
A
V
R
N
------------
E
L
T
S
Y
---
F
E
F
L
S
I
W
G
--
S
S
N
S
K
N
I
S
R
--
I
H
-
R
I
E
G
E
H
---
F
F
H
E
A
L
A
A
K
K
-----
G
V
V
--
L
I
--------------------
V
P
-
H
F
G
T
W
A
V
M
N
-----
A
W
--------
C
-
A
-
Q
F
-------
T
S
M
T
-----
I
---
L
Y
-----------------------------
K
P
V
--
K
N
A
---
D
---
A
D
R
F
--------
V
--
R
E
--
A
--
R
---
S
R
E
Q
A
N
L
-
V
--
P
T
DE-----
S
----
G
V
R
-
Q
I
F
K
A
L
K
-
Q
-------
G
E
------
T
-------
T
V
I
L
P
D
H
T
P
N
-
V
G
G
D
M
V
N
Y
F
G
V
P
L
A
S
S
N
L
S
A
----
K
L
I
Q
K
T
K
A
K
--
A
L
F
L
-----
Y
A
I
R
-----
N
-
E
----------
N
-
D
G
F
T
M
H
I
E
P
M
D
E
K
I
Y
E
G
------
T
A
D
D
G
T
Y
--
V
I
-
H
Q
------------------
A
I
E
Q
L
I
Y
Q
Y
P
E
H
Y
H
W
S
Y
K
---
R
F
K
A
N
P
A
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
56.58
16%
-9
- C6 -
-
5F2T
1
ACYLT_MYCS2
A:
[44-290]
-----------------------------------------------------------------------------------------------------------------------------------------------
G
--------
G
P
E
Q
L
R
R
N
L
A
R
V
V
G
K
-----------------------
P
P
A
------------
D
V
P
D
D
L
I
R
A
S
L
A
S
Y
A
R
Y
W
-
R
E
A
F
R
L
P
A
M
-
D
H
G
R
L
G
E
Q
-----------------------------------------------------------
L
-
D
V
I
D
I
D
---
H
L
W
S
A
L
D
A
G
R
-----
G
A
V
--
L
A
--------------------
L
P
-
H
S
G
N
W
D
M
A
G
-----
V
W
--------
L
-
V
-
Q
N
-------
Y
G
P
F
-----
T
---
T
V
-----------------------------
A
E
R
--
L
K
P
E
S
L
Y
---
R
R
F
V
--------
E
--
Y
R
--
E
--
S
L
GF
E
V
L
P
L
T
G
-
G
--
E
R
-------
P
----
P
F
E
-
V
L
A
E
R
L
T
-
D
-------
N
R
------
P
-------
I
C
L
M
A
E
R
D
L
T
-
R
S
G
V
Q
V
D
F
F
G
E
A
T
R
M
P
A
G
P
A
----
K
L
A
I
E
T
G
A
A
--
L
F
P
V
-----
H
C
W
F
E
G
---
D
---------------
G
W
G
M
R
V
Y
P
E
L
D
T
-
S
S
G
------
D
V
T
A
I
T
Q
--
A
L
-
A
D
------------------
R
F
A
A
N
I
A
T
Y
P
A
D
W
H
M
L
Q
P
---
Q
W
I
A
D
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
49.73
13%
2
- C6 -
-
5F2T
1
ACYLT_MYCS2
B:
[37-296]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
--
Y
A
A
R
-
N
G
G
P
E
Q
L
R
R
-
N
L
A
R
V
V
G
K
P
P
A
D
V
P
D
-
D
L
I
R
A
S
L
A
S
------------
Y
A
R
Y
W
---
R
E
A
F
R
L
P
A
--
M
D
H
G
-
R
L
G
E
--
Q
L
-
D
V
I
D
I
D
---
H
L
W
S
A
L
D
A
G
R
-----
G
A
V
--
L
A
--------------------
L
P
-
H
S
G
N
W
D
M
A
G
-----
V
W
--------
L
-
V
Q
N
Y
-------
G
P
F
T
-----
T
---
V
A
-----------------------------
E
R
L
--
K
P
E
---
S
---
L
Y
R
R
--------
F
--
V
E
--
Y
--
R
---
E
S
L
G
F
E
V
-
L
--
P
L
T------
G
GERP
P
F
E
-
V
L
A
E
R
L
T
-
D
-------
N
R
------
P
-------
I
C
L
M
A
E
R
D
L
T
R
-
S
G
V
Q
V
D
F
F
G
E
A
T
R
M
P
A
G
P
A
----
K
L
A
I
E
T
G
A
A
--
L
F
P
V
-----
H
C
W
F
-----
E
-
G
------------
D
G
W
G
M
R
V
Y
P
E
L
D
T
-
S
S
G
------
D
V
T
A
I
T
Q
--
A
L
-
A
D
------------------
R
F
A
A
N
I
A
T
Y
P
A
D
W
H
M
L
Q
P
---
Q
W
I
A
D
L
S
D
E
R
R
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
43.78
41%
-294
- C6 -
-
4ZLD
2
A:
[111-132]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
Q
--
I
V
-
H
I
------------------
A
M
E
A
G
L
R
I
S
P
E
Q
W
S
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
39.18
15%
-8
- C5 -
-
1B0P
3
POR_DESAF
A:
[785-1231]
--------------------------------------------------------------------------------------------------------------------------VKSEVLPRDS
L
K
G
S
Q
F
Q
E
P
L
M
E
FSGACSGC
G
E
T
P
Y
V
R
V
I
T
Q
L
F
G
E
R
M
F
I
------
A
NATG
C
S
S
I
W
G
A
S
A
P
S
MP
Y
K
T
N
RLGQGP
A
W
G
N
S
L
F
E
D
A
A
E
Y
G
F
G
M
N
-
M
S
M
F
A
R
R
-
T
-
H
L
A
D
L
A
A
K
A
L
E
S
D
A
S
-
G
D
V
K
E
A
L
Q
G
------------
W
L
A
G
K
---
N
D
P
I
K
S
K
E
--
Y
-
G
D
-
K
L
K
K
--
L
L
-
A
G
Q
K
D
G
---
L
L
G
Q
I
A
A
M
S
D
LY
T
K
K
S
V
W
--
I
F
--------------------
G
G
-
D
G
W
A
Y
D
I
G
Y
-----
G
G
--------
L
-
D
-
H
V
-------
L
A
S
G
E
D
V
N
V
F
---
V
M
DTEVYSNTGGQSSKATPTGAVAKFAAAGK
R
T
G
--
K
K
D
---
L
---
A
R
M
V
--------
M
--
T
Y
---------
G
Y
V
Y
V
A
T
-
V
--
S
M
G------
Y
----
S
K
Q
-
Q
F
L
K
V
L
K
-
E
-------
A
E
------
S
FP
G
P
S
L
V
I
A
Y
A
T
C
I
N
Q
G
L
R
K
G
-----------
M
G
K
S
Q
D
----
V
M
N
T
A
V
K
S
G
--
Y
W
P
L
-----
F
R
Y
D
P
R
---
L
-
A
----------
A
Q
G
K
N
P
F
Q
L
D
S
K
A
P
D
G
S
V
E
------
E
F
L
M
A
Q
N
--
R
F
-
A
V
------------------
L
D
R
S
F
P
E
D
A
K
R
L
R
A
Q
V
A
H
---
E
L
D
V
R
F
K
E
L
E
H
M
A
A
TN
I
F
E
S
F
A
P
A
GGK
A
D
G
S
V
D
FGEGAEFCTRDDTPMMARPDSGEACDQNRAGT
S
E
Q
Q
G
D
L
S
K
R
T
KK----------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
35.94
20%
-32
- C2 -
-
4RGP
1
?
A:
[2-256]
---------------------------------------------------------------------------------------------------------------------------------------------
N
A
T
--------
E
Q
E
T
L
T
I
L
L
D
V
Y
-------------
A
-----
Y
Y
Q
A
Y
Q
I
V
K
A
------------
S
Q
F
F
S
---
D
D
I
I
F
L
L
E
L
L
-
K
E
R
R
E
L
N
V
D
-
F
L
F
Q
-----
N
Q
V
H
L
Q
-
E
L
E
L
T
Y
H
I
S
------------
L
----------
L
D
N
A
Y
--
E
-
E
E
-
L
L
A
N
--
Y
I
M
D
L
E
A
K
L
R
N
D
H
I
I
D
F
V
R
S
V
S
-----
P
I
L
Y
R
L
L
M
-------------------
R
L
M
Q
S
Q
V
A
D
I
N
D
-----
Y
I
--------
Y
D
A
-
K
N
-------
D
Q
Y
D
-----
T
WK
F
D
K
M
----------------------------
H
D
S
--
A
N
P
---
F
---
V
Q
N
F
--------
V
--
A
K
--
G
--
R
---
D
S
----
K
-
I
--
T
S
-------
R
----
S
L
A
-
D
F
I
Q
L
T
----------------------------------------------
D
L
P
Q
A
I
K
D
N
I
L
----
L
L
R
D
F
E
K
S
V
--
R
N
P
L
-----
A
H
---------------------------
L
I
K
P
-----
F
D
E
------
E
E
L
H
R
T
T
GF
S
S
-
Q
T
------------------
F
L
E
K
I
I
Q
L
A
V
F
S
G
I
H
Y
D
N
DKF
Y
F
D
K
V
N
E
L
I
K
R
I
Y
Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
32.51
16%
-22
- C5 -
-
4NFU
3
EDS1L_ARATH
A:
[15-633]
AFEALTGIN
G
D
L
I
T
R
S
W
S
A
S
K
Q
A
Y
L
T
ER
Y
H
K
E
E
A
GA
V
V
I
F
A
F
Q
P
S
FSEKDFFDPDNKSSFG
E
I
K
L
NRVQFPCMRKIGKG
D
V
A
T
V
N
E
A
F
L
K
N
L
E
A
V
I
DPRTS
F
Q
A
S
V
E
M
A
V
R
S
RKQ
I
V
F
T
GH
S
S
G
G
A
T
A
I
L
A
T
V
W
Y
L
E
K
Y
F
I
R
N
P
--------
N
V
Y
----
L
E
P
R
C
V
T
F
G
A
P
L
VGD
S
--
I
-----
F
S
H
A
L
G
R
E
K
W
------------
S
R
F
F
V
N
F
V
T
R
F
D
I
V
P
R
I
T
-
L
A
R
K
A
S
V
E
E
-
T
L
P
H
V
L
A
Q
L
D
P
R
N
S
S
V
Q
E
S
E
Q
R
I
T
E
------------
F
Y
T
S
V
---
M
R
D
T
S
T
V
A
--
N
-
Q
A
-
V
C
E
L
--
T
G
-
S
A
E
A
I
L
---
E
T
L
S
S
F
L
E
-------------------------------------
L
S
P
Y
R
P
A
G
T
-----
F
V
--------
F
-
S
-
T
---------
E
K
R
-----
L
---
V
A
-----------------------------
V
N
N
--
S
D
A
---
I
---
L
Q
M
L
--------
F
--
Y
T
--
C
--
Q
---
A
---------------------------------------------------------------
S
D
E
Q
E
W
S
L
----------
I
P
F
R
S
I
R
D
H
H
----
S
Y
E
E
L
V
Q
S
M
--
G
M
K
L
-----
F
N
H
L
D
G
----------------
E
N
S
I
E
S
S
L
N
D
L
G
V
S
T
R
G
R
Q
------
Y
V
Q
A
A
L
E
--
E
E
-
K
K
------------------
R
V
E
N
Q
K
K
I
I
Q
V
I
---
Q
Q
E
---
R
F
L
K
K
L
A
W
I
E
D
E
Y
K
P
K
C
Q
A
H
KNG
Y
Y
D
S
F
K
V
SNE
E
N
D
F
K
A
N
V
K
R
A
E
L
A
G
V
F
D
E
V
L
G
L
L
K
K
CQLPDEFEGD
I
D
W
I
K
L
A
T
R
Y
R
R
L
V
E
P
L
D
I
A
N
Y
H
R
H
LKNEDTGPYMKRGRP
T
R
Y
I
Y
A
Q
R
G
Y
E
H
H
I
L
KPNGMI
A
E
D
V
F
W
N
K
V
N
G
L
NLGLQ
L
E
E
I
Q
E
T
L
KNSGSECGSC
F
W
A
E
V
E
E
L
KGKPYEEV
E
V
R
V
K
T
L
E
G
M
L
R
E
W
I
T
A
GEVDEKEIFLEGS
T
F
R
K
W
W
I
T
LP
K
N
H
K
S
H
SPLRDY
M
M
D
E
I
8
HHSearch
31.27
17%
1
- C6 -
-
1K30
-
PLSB_CUCMO
A:
[128-313]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
G
H
-----
N
V
V
--
L
I
--------------------
S
N
-
H
Q
T
E
A
D
P
A
I
-----
I
S
--------
L
-
L
-
L
E
KTN
P
Y
I
A
E
N
T
I
-----
F
---
V
A
-----------------------------
G
D
R
V
L
A
D
P
---
L
C
K
P
F
S
I
G
--------
R
--
N
L
I
C
V
Y
S
K
---
K
H
M
F
D
I
P
E
L
--
T
E
T
K
R
K
A
N
T
R
----
S
L
K
-
E
M
A
L
L
L
R
G
G
-------
S
Q
------
L
-------
I
W
I
A
P
S
G
G
R
D
R
P
D
P
S
T
G
E
W
--
Y
P
A
P
F
D
A
S
S
V
D
N
M
R
R
L
I
Q
H
S
D
V
P
G
H
L
F
P
L
-----
A
L
L
C
H
D
IM-
P
P
P
S
Q
V
E
I
E
IRV
I
A
F
N
G
A
G
L
S
V
A
P
E
I
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
30.46
17%
12
- C6 -
-
1IUQ
5
PLSB_CUCMO
A:
[127-312]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
G
H
-----
N
V
V
--
L
I
--------------------
S
N
-
H
Q
T
E
A
D
P
A
I
-----
I
S
--------
L
-
L
-
L
E
KTN
P
Y
I
A
E
N
T
I
-----
F
---
V
A
-----------------------------
G
D
R
VL
A
D
P
---
L
C
K
P
F
S
I
G
--------
R
--
N
L
IC
V
YS
K
---
K
H
M
F
D
I
P
E
L
--
T
E
T
K
R
K
A
N
T
R
----
S
L
K
-
E
M
A
L
L
L
R
G
G
-------
S
Q
------
L
-------
I
W
I
A
P
S
G
G
R
D
R
P
D
P
S
T
G
E
W
--
Y
P
A
P
F
D
A
S
S
V
D
N
M
R
R
L
I
Q
H
S
D
V
P
G
H
L
F
P
L
-----
A
L
L
C
H
D
IMP
P
-
P
R
V
I
-------
A
F
N
G
A
G
L
S
V
A
P
E
I
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
29.58
50%
-211
- C3 -
-
4RL8
1
?
A:
[146-171]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
H
L
G
-
E
K
W
A
V
D
L
V
G
D
------
A
-------
I
W
Y
S
D
N
D
D
F
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
25.00
17%
31
- C4 -
-
1VZ0
-
SP0J_THET2
A:
[23-208]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
--
R
L
-
P
L
A
S
I
R
---
P
N
P
R
Q
P
R
K
R
F
-----
A
E
E
--
S
L
--------------------
K
E
-
L
A
D
S
I
R
E
K
G
LL
Q
P
L
L
V
--------
R
-
P
-
Q
G
-------
D
G
Y
E
-----
L
---
V
A
-----------------------------
G
E
R
--
R
Y
R
---
A
---
A
L
M
A
--------
G
--
L
Q
--
E
--
V
---
P
A
V
V
K
D
L
-
T
--
D
R
-------
E
----
A
L
E
L
A
L
V
E
N
L
Q
-
R
-------
E
D
LS
P
V
E
E
A
-------
R
G
Y
Q
A
L
L
E
M
G
L
T
Q
E
E
V
A
R
R
V
G
K
A
R
S
T
V
A
N
A
L
----
R
L
L
Q
L
P
P
E
A
--
L
E
A
L
-----
E
---
R
G
---
E
-
I
----------
T
A
G
H
A
R
A
L
L
M
L
--------------
E
P
E
D
R
L
W
--
G
L
-
K
E
------------------
I
L
E
K
G
L
S
V
R
Q
A
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
24.78
10%
-41
* C5 *
-
2ACV
1
?
A:
[3-463]
--------------------------------------------------------M
S
D
I
N
K
N
S
E
L
I
F
I
P
A
P
G
I
G
H
L
A
S
A
L
E
F
A
K
L
L
T
N
H
D
K
N
L
Y
I
T
V
F
C
I
K
F
PGMPFA
D
S
Y
I
K
S
V
L
ASQPQ
I
Q
L
I
D
L
P
EVEPPP
Q
E
L
L
K
S
P
E
F
--------
Y
I
L
T
F
L
E
S
L
I
P
H
V
K
A
T
I
K
T
I
LSNKV
V
-----
G
L
V
L
D
F
F
C
V
S
------------
M
I
D
V
G
N
E
F
G
I
P
S
Y
L
F
L
T
S
-
N
V
G
F
L
S
L
M
L
-
S
L
K
N
R
Q
I
E
E
V
F
D
D
S
D
-
R
D
H
Q
L
L
N
I
P
------------
G
I
S
N
Q
---
V
P
--
S
N
V
L
--
P
-
D
A
-
C
F
N
K
--
D
G
-
G
Y
I
A
Y
Y
---
K
L
A
E
R
F
R
D
T
K
-----
G
I
I
--
V
N
--------------------
T
F
-
S
D
L
E
Q
S
S
I
D
-----
A
L
--------
Y
-
D
-
H
D
-------
E
K
I
P
-----
P
---
I
Y
A
VGPLLDLK
G
Q
P
N
PKLD------------
Q
A
Q
--
H
D
L
---
I
---
L
K
W
L
D
E
QPDKS
V
V
--
F
L
--
C
--
F
---
G
S
M
-
G
V
S
-
F
--
G
P
-------
S
----
Q
I
R
-
E
I
A
L
G
L
K
-
H
S
G-----
V
R
------
F
-------
L
W
S
N
S
A
E
K
K
V
F
P
E
G
F
L
E
W
M
E
L
E
G
K
G
M
I
C
G
W
A
----
P
Q
V
E
V
L
A
H
K
--
A
I
G
G
-----
F
V
S
H
C
G
--------------------
W
N
S
I
L
E
S
M
W
F
G
V
P
I
L
T
W
P
I
YA
E
Q
Q
L
N
A
F
--
R
L
-
V
K
EWGVGLGLRVDYRKGSDV
V
A
A
E
E
I
E
K
G
L
K
D
L
M
D
K
D
S
---
I
V
H
K
K
V
Q
E
M
K
E
M
S
R
N
A
V
VDGG
S
S
L
I
S
V
G
K
L
I
D
D
I
T
G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
20.79
18%
-71
- C7 -
-
3DSO
-
COPK_CUPMC
A:
[11-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
Q
-
D
-------
G
S
------
K
-------
V
H
V
F
K
D
G
K
M
G
M
-----
E
N
K
F
G
K
S
M
N
M
P
E
G
K
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
18.56
11%
24
- C1 -
-
3WPA
-
?
A:
[65-410]
----------------------------------------------------------------------------------------------------------------------------------------
N
V
A
Q
G
N
Q
T
--------
N
V
G
D
A
L
T
A
L
D
N
A
I
N
T
A
A
T
T
------
S
-----
K
S
T
V
S
N
--
G
Q
------------
N
I
V
V
S
K
S
K
N
A
D
G
S
D
N
Y
E
V
-
S
T
A
K
D
L
T
V
D
-
S
V
K
A
G
D
T
V
L
N
N
A
G
I
T
-
I
G
N
N
A
V
V
L
N
NT
G
L
T
I
S
G
G
P
S
V
T
L
A
G
I
DAG
N
K
T
I
Q
N
V
A
--
N
-
A
V
-
N
A
T
D
--
A
V
-
N
K
G
Q
L
D
---
S
A
I
N
N
V
N
N
N
V
-----
N
E
L
--
A
N
N
AVKYDDASKD
K
I
T
L
GGGAT
G
T
-
T
I
T
N
V
K
D
G
T
-----
V
A
QGSK
D
A
V
N
G
-
G
-
Q
L
-------
W
N
V
Q
-----
Q
---
Q
V
-----------------------------
D
Q
N
--
T
T
D
---
I
---
S
N
I
K
--------
N
--
D
I
--
N
--
N
---
G
T
V
G
L
V
Q
-
Q
--
A
G
-------
K
----
D
A
P
-
V
T
V
A
K
D
T
-
G
-------
G
T
------
T
-------
V
N
V
A
G
T
D
G
N
R
V
V
T
G
V
K
E
G
A
V
N
A
T
S
K
D
A
V
N
G
S
----
Q
L
N
T
T
N
Q
A
V
--
V
N
Y
L
GGG
A
G
Y
D
N
I
T
G
---
S
-
F
----------
T
A
P
S
Y
T
V
---
G
D
S
K
Y
N
N
V
G
------
G
A
I
D
A
L
N
--
Q
A
-
D
Q
------------------
A
L
N
S
K
I
D
N
V
S
N
K
L
D
N
A
F
R
---
I
T
N
N
R
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
11.45
18%
-19
* C7 *
-
2LEL
-
COPK_CUPMC
A:
[11-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
Q
-
D
-------
G
S
------
K
-------
V
H
V
F
K
D
G
K
M
G
M
-----
E
N
K
F
G
K
S
M
N
M
P
E
G
K
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
6.29
41%
-
* C6 *
-
4ZLC
-
RC3H2_HUMAN
A:
[281-302]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
Q
--
I
V
-
H
I
------------------
A
M
E
A
G
L
R
I
S
P
E
Q
W
S
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------