@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLB7: (2017-11-01 )
MSNMQLDTLRRIVQEINASVSLHESLDIMVNQVAEAMKVDVCSIYLLDERNQRYVLMASKGLNPESVGHVSLQLGEGLVGLVGQREEIVNLDNAPKHERFLYLPETGEEIYNSFLGVPVMYRRKVMGVLVVQNRLPQDFSEAAESFLVTLCAQLSGVIAHAHAVGNIDVFRKPSNGPAYKTFQGVSGAGGVALGRAIILYPPADLGSVPDREAEDISDELRILDQAISSVRSEIRSLDEKMHDSLMAEERALFSVFLRMLDENALPAEIKELIRDGHWAQGAVRRVIEKHTALFAQMEDDYLRERVSDLKDLGRRILAYLQEEDSNHRELSPDSILIGEEISTAALVELPVDNIAAIVTSEGAANSHMVIVARALGIPTVVGVTELPVNTLDDAEMIVDAYQGRVFVNPPRRLRQRYKEIQKEDEQIAKDLKQYETKEAITPDGVSVQLFVNTGLMIDVVRGVQRGAQGVGLYRSEIPFMLRERFPGEEEQRAIYRQQLSHFANKPVVMRTLDIGADKDLPYFSIEEENSALGWRGIRFTLDHPEIFSAQIRAMLKASIGLNNLHILLPMVTTVSEVEEVLYLLERDWIAVQEEEQVKITKPKIGIMVEVPSVLLQIDEFAELVDFFSVGSNDLTQYLLAVDRNNPHVANVYSHFHPSILRALTRLVKECHKYQKPVSICGEMAGDPLSAILLMAMGFNTLSMSSSNILRVRKAICHVPMSDAQKLLDDVMKMNNPLIVKSWLEYYFKTHGLADMVKSNRLVSV
Atome Classification :
(20 SA)
---------------------------.........10........20........30........40........50---.........60----------------.........70........80........90....---....100.....---------..110.......120.......130.......140.......150.......160.......170.......180.......190.......200.....-------..210......------...220.......230.......240.......250..-----.....260-........270-....-....-.280.......290.......300.......310....----------.-..-320...-....330.......340.......350.......360.......370.......380.....------------..390.......400.......410.......420.......430.......440....-...450.......460.......470.......480..----------..-----------.--------------------..-----------490.......500.......510.......520----------------------.------------------------.------------------------.-.-...-.530.......540.......550.......-----560--..---.-------......570.......580.......590-.-......600-.......610.......620.......630.......640.....--.-.--650------.-------.-------...-------------....660.......670------.--..------.--...680.......690.......700.......710.......720---------.......730.......740.......750.......760..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------MSNM
Q
L
D
T
L
R
R
I
V
Q
E
I
N
ASV
S
L
H
E
S
L
D
I
M
V
N
Q
V
A
E
A
M
K
V
D
V
C
S
I
Y
L
LDER----N
Q
R
Y
V
L
M
ASK-----------------GLNPESV
G
H
V
S
L
QLGE
G
L
V
G
L
VG
Q
R
E
E
IVNLDNAP---KH
E
R
F
L
YLPET
G
---------
E
E
I
Y
N
S
FLG
V
P
V
M
Y
R
R
K
V
M
G
V
L
V
V
Q
N
RLP
Q
D
F
S
E
A
A
E
S
F
L
V
T
L
C
A
Q
L
S
G
V
I
A
H
A
HAVGN
I
D
V
F
RKPSNGPAY
K
T
FQGVSGAGGVALG
R
A
I
I
L
YPPADLGS-------VPD--R
E
A
E
D
I
------
S
D
E
L
R
I
L
D
Q
A
I
S
S
V
R
S
E
I
R
S
L
D
E
K
M
H
D
S
L
M
A
E
E
R
A
L
F
S
-----
V
F
L
R
M
L
D--ENAL
P
A
E
I
K
---
E
L
I
R-DGHW-
A
Q
G
A
V
R
R
V
I
E
K
H
T
A
L
F
A
QM
E
D
D
Y
L
R
E
R
V
S
D
L
K
D
L
G
R
R
I
----------
L
-
A
Y
-
L
Q
EEDS-NHRELSPD
S
I
L
IGEEIS
T
A
A
L
V
ELPVDN
I
A
A
I
VTSEGAANS
H
M
V
I
V
A
RALGIPTVVGVTELP------------VNTLD
D
A
E
M
I
V
D
A
YQ
G
R
V
FVN
P
P
R
R
L
R
Q
R
Y
K
E
I
Q
K
E
D
E
Q
I
A
K
D
L
K
Q
Y
E
TKEAITPDG
V
S
-
V
Q
L
F
VNTG
L
M
I
D
V
V
R
G
V
Q
RGAQGVG
L
Y
R
S
E
I
P
F
M
L
R
E
R----------FP-----------
G
--------------------
E
E
-----------
E
Q
R
A
I
Y
R
Q
Q
L
S
H
FANK
P
V
V
M
R
T
L
DIGADKDLP-----------------------
Y
------------------------
F
------------------------
S
-I-EEE-NSALGWR
G
I
R
F
T
LD
H
P
E
I
F
S
A
Q
I
R
A
M
L
K
A
SI-----G----LN---
N
-------
L
H
I
L
L
P
M
V
T
T
V
S
E
V
E
E
V
L
Y
L
L
E
RD
W
I
AVQ-E-EE
Q
V
K
ITKP-K
I
G
I
M
V
E
V
P
S
V
L
L
Q
I
D
E
F
A
E
L
V
D
F
F
SVG
S
N
D
L
T
Q
Y
L
L
AVDRNNP
H
--
V
-
A
--
N
--------
V
-------
Y
-------
S
HF-------------
H
P
S
I
L
R
A
L
T
R
L
V
K
E
C
H
K
------Y--Q
K
------
P
--
V
S
I
C
G
E
MAG
D
P
L
S
A
I
L
L
M
A
MGF
N
T
LSMSS
S
N
I
L
R
V
R
K
A
ICHV
P
M
S
D
---------
A
Q
K
L
L
D
D
V
M
KMNN
P
L
I
V
K
S
W
L
E
Y
Y
F
K
TH
G
L
A
D
M
V
KSNRLVSV
2
PsiBlast_PDB
77.77
32%
-19
* C1 *
-
2WQD
-
PT1_STAAU
A:
[3-550]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
K
G
I
A
A
S
D
G
V
A
I
A
K
A
Y
L
L
V
E
P
-
D
L
T
F
-------
D
K
N
--
E
K
V
T
D
V
------
E
G
E
V
A
K
F
N
S
A
I
E
A
S
K
V
E
L
T
K
I
R
N
N
A
E
V
Q
L
G
A
D
K
A
A
I
F
D
-----
A
H
L
L
V
L
D
--
D
P
E
L
I
Q
P
I
Q
---
D
K
I
K
-
N
E
N
A
N
A
A
T
A
L
T
D
V
T
T
Q
F
V
T
I
F
E
S
M
D
N
E
Y
M
K
E
R
A
A
D
I
R
D
V
S
K
R
V
----------
L
-
S
H
I
L
G
V
E
L
P
-
N
P
S
M
I
D
E
S
V
V
I
V
G
N
D
L
T
P
S
D
T
A
Q
L
N
K
E
F
V
Q
G
F
A
T
N
I
G
G
R
T
S
A
S
A
I
M
S
R
S
L
E
I
P
A
I
V
G
T
K
S
I
T
------------
Q
E
V
K
Q
G
D
M
I
I
V
D
G
L
N
G
D
V
I
V
N
P
T
E
D
E
L
I
A
Y
Q
D
K
R
E
R
Y
F
A
D
K
K
E
L
Q
K
L
R
D
A
D
T
V
T
V
D
G
V
H
-
A
E
L
A
A
N
I
G
T
P
N
D
L
P
G
V
I
E
N
G
A
Q
G
I
G
L
Y
R
T
E
F
L
Y
M
G
R
D
Q
----------
M
P
-----------
T
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
L
E
A
M
G
G
K
R
V
V
V
R
T
L
D
I
G
G
D
K
E
L
S
-----------------------
Y
------------------------
L
------------------------
N
-
L
-
P
E
E
M
N
P
F
L
G
Y
R
A
I
R
L
S
L
A
Q
Q
D
I
F
R
P
Q
L
R
A
L
L
R
A
S
V
----------
Y
G
---
K
-------
L
N
I
M
F
P
M
V
A
T
I
N
E
F
R
E
A
K
A
I
L
L
E
E
K
E
N
L
K
-
N
-
E
G
H
D
I
S
D
D
I
-
E
L
G
I
M
V
E
I
P
A
T
A
A
L
A
D
V
F
A
K
E
V
D
F
F
S
I
G
T
N
D
L
I
Q
Y
T
L
A
A
D
R
M
S
E
R
--
V
-
S
--
Y
--------
L
-------
Y
-------
Q
P
Y
-------------
N
P
S
I
L
R
L
V
K
Q
V
I
E
A
S
H
K
------
E
--
G
K
------
W
--
T
G
M
C
G
E
M
A
G
D
E
T
A
I
P
L
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
L
K
A
R
R
Q
I
N
G
L
S
K
N
E
---------
M
T
E
L
--------------------------------------
22
HHSearch
75.31
32%
38
- C1 -
-
2WQD
-
PT1_STAAU
A:
[2-571]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
L
I
K
G
I
A
A
S
D
G
V
A
I
A
K
A
Y
L
L
V
E
P
D
L
T
---------
F
D
K
NE
K
V
-
T
D
V
------
E
G
E
V
A
K
F
N
S
A
I
E
A
S
K
V
E
L
T
K
I
R
N
N
A
E
V
Q
L
G
A
D
K
A
A
I
F
D
-----
A
H
L
L
V
L
D
--
D
P
E
L
I
Q
P
I
Q
---
D
K
I
K
N
E
N
A
N
-
A
A
T
A
L
T
D
V
T
T
Q
F
V
T
I
F
E
S
M
D
N
E
Y
M
K
E
R
A
A
D
I
R
D
V
S
K
R
V
----------
L
-
S
H
-
I
L
G
V
E
L
P
N
P
S
M
I
D
E
S
V
V
I
V
G
N
D
L
T
P
S
D
T
A
Q
L
N
K
E
F
V
Q
G
F
A
T
N
I
G
G
R
T
S
A
S
A
I
M
S
R
S
L
E
I
P
A
I
V
G
T
K
S
I
T
------------
Q
E
V
K
Q
G
D
M
I
I
V
D
G
L
N
G
D
V
I
V
N
P
T
E
D
E
L
I
A
Y
Q
D
K
R
E
R
Y
F
A
D
K
K
E
L
Q
K
L
R
D
A
D
T
V
T
V
D
G
V
H
-
A
E
L
A
A
N
I
G
T
P
N
D
L
P
G
V
I
E
N
G
A
Q
G
I
G
L
Y
R
T
E
F
L
Y
M
G
R
D
Q
----------
M
P
-----------
T
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
L
E
A
M
G
G
K
R
V
V
V
R
T
L
D
I
G
G
D
K
E
L
S
-----------------------
Y
------------------------
L
------------------------
N
-
L
P
E
E
M
-
N
P
F
L
G
Y
R
A
I
R
L
S
L
A
Q
Q
D
I
F
R
P
Q
L
R
A
L
L
R
A
S
V
----------
Y
G
---
K
-------
L
N
I
M
F
P
M
V
A
T
I
N
E
F
R
E
A
K
A
I
L
L
E
E
K
E
N
L
K
-
N
-
E
G
H
D
I
S
D
D
I
-
E
L
G
I
M
V
E
I
P
A
T
A
A
L
A
D
V
F
A
K
E
V
D
F
F
S
I
G
T
N
D
L
I
Q
Y
T
L
A
A
D
R
M
S
E
R
--
V
-
S
--
Y
--------
L
-------
Y
-------
Q
P
Y
-------------
N
P
S
I
L
R
L
V
K
Q
V
I
E
A
S
H
K
------
E
--
G
K
------
W
--
T
G
M
C
G
E
M
A
G
D
E
T
A
I
P
L
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
L
K
A
R
R
Q
I
N
G
L
S
K
N
E
---------
M
T
E
L
A
N
R
A
V
D
C
A
T
Q
E
E
V
I
E
L
V
N
N
Y
V
-----------------
5
PsiBlast_PDB
74.91
32%
-25
- C1 -
-
2XDF
-
PT1_ECOLI
A:
[4-569]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
L
A
S
P
G
I
A
F
G
K
A
L
L
L
K
E
D
E
I
V
I
D
-------
R
K
K
--
I
S
A
D
Q
V
------
D
Q
E
V
E
R
F
L
S
G
R
A
K
A
S
A
Q
L
E
T
I
K
T
K
A
G
E
T
F
G
E
E
K
E
A
I
F
E
-----
G
H
I
M
L
L
E
--
D
E
E
L
E
Q
E
I
I
---
A
L
I
K
-
D
K
H
M
T
A
D
A
A
A
H
E
V
I
E
G
Q
A
S
A
L
E
E
L
D
D
E
Y
L
K
E
R
A
A
D
V
R
D
I
G
K
R
L
----------
L
R
N
I
-
L
G
L
K
I
I
-
D
L
S
A
I
Q
D
E
V
I
L
V
A
A
D
L
T
P
S
E
T
A
Q
L
N
L
K
K
V
L
G
F
I
T
D
A
G
G
R
T
S
H
T
S
I
M
A
R
S
L
E
L
P
A
I
V
G
T
G
S
V
T
------------
S
Q
V
K
N
D
D
Y
L
I
L
D
A
V
N
N
Q
V
Y
V
N
P
T
N
E
V
I
D
K
M
R
A
V
Q
E
Q
V
A
S
E
K
A
E
L
A
K
L
K
D
L
P
A
I
T
L
D
G
H
Q
-
V
E
V
C
A
N
I
G
T
V
R
D
V
E
G
A
E
R
N
G
A
E
G
V
G
L
Y
R
T
E
F
L
F
M
D
R
D
A
----------
L
P
-----------
T
--------------------
E
E
-----------
E
Q
F
A
A
Y
K
A
V
A
E
A
C
G
S
Q
A
V
I
V
R
T
M
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
M
------------------------
N
-
F
P
K
E
E
-
N
P
F
L
G
W
R
A
I
R
I
A
M
D
R
R
E
I
L
R
D
Q
L
R
A
I
L
R
A
S
------
A
----
F
G
---
K
-------
L
R
I
M
F
P
M
I
I
S
V
E
E
V
R
A
L
R
K
E
I
E
I
Y
K
Q
E
L
R
-
D
-
E
G
K
A
F
D
E
S
I
-
E
I
G
V
M
V
E
T
P
A
A
A
T
I
A
R
H
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
G
N
D
M
--
I
-
S
--
H
--------
L
-------
Y
-------
Q
P
M
-------------
S
P
S
V
L
N
L
I
K
Q
V
I
D
A
S
H
A
------
E
--
G
K
------
W
--
T
G
M
C
G
E
L
A
G
D
E
R
A
T
L
L
L
L
G
M
G
L
D
E
F
S
M
S
A
I
S
I
P
R
I
K
K
I
I
R
N
T
N
F
E
D
A
K
V
L
A
E
Q
A
L
A
Q
P
T
T
D
E
L
M
T
L
V
N
K
F
I
--------------------------
4
PsiBlast_PDB
74.25
32%
-23
- C1 -
-
2KX9
-
PT1_ECOLI
A:
[4-569]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
L
A
S
P
G
I
A
F
G
K
A
L
L
L
K
E
D
E
I
V
I
D
-------
R
K
K
--
I
S
A
D
Q
V
------
D
Q
E
V
E
R
F
L
S
G
R
A
K
A
S
A
Q
L
E
T
I
K
T
K
A
G
E
T
F
G
E
E
K
E
A
I
F
E
-----
G
H
I
M
L
L
E
--
D
E
E
L
E
Q
E
I
I
---
A
L
I
K
-
D
K
H
M
T
A
D
A
A
A
H
E
V
I
E
G
Q
A
S
A
L
E
E
L
D
D
E
Y
L
K
E
R
A
A
D
V
R
D
I
G
K
R
L
----------
L
R
N
I
-
L
G
L
K
I
I
-
D
L
S
A
I
Q
D
E
V
I
L
V
A
A
D
L
T
P
S
E
T
A
Q
L
N
L
K
K
V
L
G
F
I
T
D
A
G
G
R
T
S
H
T
S
I
M
A
R
S
L
E
L
P
A
I
V
G
T
G
S
V
T
------------
S
Q
V
K
N
D
D
Y
L
I
L
D
A
V
N
N
Q
V
Y
V
N
P
T
N
E
V
I
D
K
M
R
A
V
Q
E
Q
V
A
S
E
K
A
E
L
A
K
L
K
D
L
P
A
I
T
L
D
G
H
Q
-
V
E
V
C
A
N
I
G
T
V
R
D
V
E
G
A
E
R
N
G
A
E
G
V
G
L
Y
R
T
E
F
L
F
M
D
R
D
A
----------
L
P
-----------
T
--------------------
E
E
-----------
E
Q
F
A
A
Y
K
A
V
A
E
A
C
G
S
Q
A
V
I
V
R
T
M
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
M
------------------------
N
-
F
P
K
E
E
-
N
P
F
L
G
W
R
A
I
R
I
A
M
D
R
R
E
I
L
R
D
Q
L
R
A
I
L
R
A
S
------
A
----
F
G
---
K
-------
L
R
I
M
F
P
M
I
I
S
V
E
E
V
R
A
L
R
K
E
I
E
I
Y
K
Q
E
L
R
-
D
-
E
G
K
A
F
D
E
S
I
-
E
I
G
V
M
V
E
T
P
A
A
A
T
I
A
R
H
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
G
N
D
M
--
I
-
S
--
H
--------
L
-------
Y
-------
Q
P
M
-------------
S
P
S
V
L
N
L
I
K
Q
V
I
D
A
S
H
A
------
E
--
G
K
------
W
--
T
G
M
C
G
E
L
A
G
D
E
R
A
T
L
L
L
L
G
M
G
L
D
E
F
S
M
S
A
I
S
I
P
R
I
K
K
I
I
R
N
T
N
F
E
D
A
K
V
L
A
E
Q
A
L
A
Q
P
T
T
D
E
L
M
T
L
V
N
K
F
I
--------------------------
3
PsiBlast_PDB
73.95
32%
-19
- C1 -
-
2N5T
-
PT1_ECOLI
A:
[4-569]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
L
A
S
P
G
I
A
F
G
K
A
L
L
L
K
E
D
E
I
V
I
D
-------
R
K
K
--
I
S
A
D
Q
V
------
D
Q
E
V
E
R
F
L
S
G
R
A
K
A
S
A
Q
L
E
T
I
K
T
K
A
G
E
T
F
G
E
E
K
E
A
I
F
E
-----
G
H
I
M
L
L
E
--
D
E
E
L
E
Q
E
I
I
---
A
L
I
K
-
D
K
H
M
T
A
D
A
A
A
H
E
V
I
E
G
Q
A
S
A
L
E
E
L
D
D
E
Y
L
K
E
R
A
A
D
V
R
D
I
G
K
R
L
----------
L
R
N
I
-
L
G
L
K
I
I
-
D
L
S
A
I
Q
D
E
V
I
L
V
A
A
D
L
T
P
S
E
T
A
Q
L
N
L
K
K
V
L
G
F
I
T
D
A
G
G
R
T
S
H
T
S
I
M
A
R
S
L
E
L
P
A
I
V
G
T
G
S
V
T
------------
S
Q
V
K
N
D
D
Y
L
I
L
D
A
V
N
N
Q
V
Y
V
N
P
T
N
E
V
I
D
K
M
R
A
V
Q
E
Q
V
A
S
E
K
A
E
L
A
K
L
K
D
L
P
A
I
T
L
D
G
H
Q
-
V
E
V
C
A
N
I
G
T
V
R
D
V
E
G
A
E
R
N
G
A
E
G
V
G
L
Y
R
T
E
F
L
F
M
D
R
D
A
----------
L
P
-----------
T
--------------------
E
E
-----------
E
Q
F
A
A
Y
K
A
V
A
E
A
C
G
S
Q
A
V
I
V
R
T
M
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
M
------------------------
N
-
F
P
K
E
E
-
N
P
F
L
G
W
R
A
I
R
I
A
M
D
R
R
E
I
L
R
D
Q
L
R
A
I
L
R
A
S
------
A
----
F
G
---
K
-------
L
R
I
M
F
P
M
I
I
S
V
E
E
V
R
A
L
R
K
E
I
E
I
Y
K
Q
E
L
R
-
D
-
E
G
K
A
F
D
E
S
I
-
E
I
G
V
M
V
E
T
P
A
A
A
T
I
A
R
H
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
G
N
D
M
--
I
-
S
--
H
--------
L
-------
Y
-------
Q
P
M
-------------
S
P
S
V
L
N
L
I
K
Q
V
I
D
A
S
H
A
------
E
--
G
K
------
W
--
T
G
M
C
G
E
L
A
G
D
E
R
A
T
L
L
L
L
G
M
G
L
D
E
F
S
M
S
A
I
S
I
P
R
I
K
K
I
I
R
N
T
N
F
E
D
A
K
V
L
A
E
Q
A
L
A
Q
P
T
T
D
E
L
M
T
L
V
N
K
F
I
--------------------------
6
PsiBlast_PDB
73.92
31%
-23
- C1 -
-
2L5H
-
PT1_ECOLI
A:
[4-569]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
L
A
S
P
G
I
A
F
G
K
A
L
L
L
K
E
D
E
I
V
I
D
-------
R
K
K
--
I
S
A
D
Q
V
------
D
Q
E
V
E
R
F
L
S
G
R
A
K
A
S
A
Q
L
E
T
I
K
T
K
A
G
E
T
F
G
E
E
K
E
A
I
F
E
-----
G
H
I
M
L
L
E
--
D
E
E
L
E
Q
E
I
I
---
A
L
I
K
-
D
K
H
M
T
A
D
A
A
A
H
E
V
I
E
G
Q
A
S
A
L
E
E
L
D
D
E
Y
L
K
E
R
A
A
D
V
R
D
I
G
K
R
L
----------
L
R
N
I
-
L
G
L
K
I
I
-
D
L
S
A
I
Q
D
E
V
I
L
V
A
A
D
L
T
P
S
E
T
A
Q
L
N
L
K
K
V
L
G
F
I
T
D
A
G
G
R
T
S
Q
T
S
I
M
A
R
S
L
E
L
P
A
I
V
G
T
G
S
V
T
------------
S
Q
V
K
N
D
D
Y
L
I
L
D
A
V
N
N
Q
V
Y
V
N
P
T
N
E
V
I
D
K
M
R
A
V
Q
E
Q
V
A
S
E
K
A
E
L
A
K
L
K
D
L
P
A
I
T
L
D
G
H
Q
-
V
E
V
C
A
N
I
G
T
V
R
D
V
E
G
A
E
R
N
G
A
E
G
V
G
L
Y
R
T
E
F
L
F
M
D
R
D
A
----------
L
P
-----------
T
--------------------
E
E
-----------
E
Q
F
A
A
Y
K
A
V
A
E
A
C
G
S
Q
A
V
I
V
R
T
M
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
M
------------------------
N
-
F
P
K
E
E
-
N
P
F
L
G
W
R
A
I
R
I
A
M
D
R
R
E
I
L
R
D
Q
L
R
A
I
L
R
A
S
------
A
----
F
G
---
K
-------
L
R
I
M
F
P
M
I
I
S
V
E
E
V
R
A
L
R
K
E
I
E
I
Y
K
Q
E
L
R
-
D
-
E
G
K
A
F
D
E
S
I
-
E
I
G
V
M
V
E
T
P
A
A
A
T
I
A
R
H
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
G
N
D
M
--
I
-
S
--
H
--------
L
-------
Y
-------
Q
P
M
-------------
S
P
S
V
L
N
L
I
K
Q
V
I
D
A
S
H
A
------
E
--
G
K
------
W
--
T
G
M
C
G
E
L
A
G
D
E
R
A
T
L
L
L
L
G
M
G
L
D
E
F
S
M
S
A
I
S
I
P
R
I
K
K
I
I
R
N
T
N
F
E
D
A
K
V
L
A
E
Q
A
L
A
Q
P
T
T
D
E
L
M
T
L
V
N
K
F
I
--------------------------
1
PsiBlast_PDB
63.53
90%
-188
- C2 -
-
3CI6
3
?
A:
[5-170]
----------------------------
S
N
M
Q
L
D
T
L
R
R
I
V
Q
E
I
N
S
S
V
S
L
H
D
S
L
D
I
M
V
N
Q
V
A
D
A
M
K
V
D
V
C
S
I
Y
L
L
D
E
R
----
N
Q
R
Y
L
L
M
A
S
K
-----------------
G
L
N
P
E
S
V
G
H
V
S
L
Q
L
S
E
G
L
V
G
L
V
G
Q
R
E
E
I
V
N
L
E
N
A
S
---
K
H
E
R
F
------------------
I
Y
N
S
F
L
G
V
P
V
M
Y
R
R
K
V
M
G
V
L
V
V
Q
N
K
Q
P
Q
D
F
S
E
A
A
E
S
F
L
V
T
L
C
A
Q
L
S
G
V
I
A
H
A
H
A
V
G
N
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
61.34
42%
-24
- C1 -
-
2XZ9
1
?
B:
[7-322]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
-
P
K
E
M
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
------
A
----
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
-
E
V
K
A
E
L
-
D
-
R
E
G
V
K
Y
D
K
E
I
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
N
M
S
E
A
R
E
I
E
K
M
M
K
D
V
I
K
D
---------------
8
PsiBlast_PDB
61.31
42%
-25
- C1 -
-
2XZ7
1
?
A:
[5-324]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
Q
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
-
P
K
E
M
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
------
A
----
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
-
E
V
K
A
E
L
-
D
-
R
E
G
V
K
Y
D
K
E
I
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
N
M
S
E
A
R
E
I
E
K
M
M
K
D
V
I
K
D
I
--------------
7
PsiBlast_PDB
59.92
42%
-19
- C1 -
-
2XZ9
1
?
A:
[7-323]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
-
P
K
E
M
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
------
A
----
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
-
E
V
K
A
E
L
-
D
-
R
E
G
V
K
Y
D
K
E
I
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
N
M
S
E
A
R
E
I
E
K
M
M
K
D
V
I
K
D
I
--------------
27
HHSearch
59.14
41%
-42
- C1 -
-
2XZ9
1
?
A:
[7-323]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
P
K
E
M
-
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
A
----------
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
E
V
K
A
E
L
D
-
R
-
E
G
V
K
Y
D
K
E
I
-
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
N
M
S
E
A
R
E
I
E
K
M
M
K
D
V
I
K
D
I
--------------
9
PsiBlast_PDB
58.34
42%
-29
- C1 -
-
2BG5
-
?
A:
[253-553]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
Q
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
P
K
E
M
-
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
------
A
----
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
-
E
V
K
A
E
L
-
D
-
R
E
G
V
K
Y
D
K
E
I
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
---------------------------------
26
HHSearch
57.32
41%
-43
- C1 -
-
2BG5
-
?
D:
[255-572]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
K
D
L
P
A
E
T
P
D
G
K
K
-
V
M
L
A
A
N
I
G
T
P
K
D
V
A
S
A
L
A
N
G
A
E
G
V
G
L
F
R
T
E
F
L
Y
M
D
R
N
S
----------
L
P
-----------
S
--------------------
E
E
-----------
E
Q
F
E
A
Y
K
E
V
V
E
K
M
G
G
R
P
V
T
I
R
T
L
D
I
G
G
D
K
E
L
P
-----------------------
Y
------------------------
L
------------------------
D
-
M
P
K
E
M
-
N
P
F
L
G
Y
R
A
I
R
L
C
L
D
R
P
D
I
F
K
T
Q
L
R
A
I
L
R
A
S
A
----------
Y
G
---
N
-------
V
Q
I
M
Y
P
M
I
S
S
V
E
E
V
R
K
A
N
S
I
L
E
E
V
K
A
E
L
D
-
R
-
E
G
V
K
Y
D
K
E
I
-
K
V
G
I
M
V
E
I
P
S
A
A
V
T
A
D
I
L
A
K
E
V
D
F
F
S
I
G
T
N
D
L
T
Q
Y
T
L
A
V
D
R
M
N
E
H
--
V
-
K
--
E
--------
Y
-------
Y
-------
Q
P
F
-------------
H
P
A
I
L
R
L
V
K
M
V
I
D
A
A
H
K
------
E
--
G
K
------
F
--
A
A
M
C
G
E
M
A
G
D
P
L
A
A
V
I
L
L
G
L
G
L
D
E
F
S
M
S
A
T
S
I
P
E
I
K
N
I
I
R
N
V
E
Y
E
K
---------
A
K
E
I
A
E
K
A
L
N
M
S
E
A
R
E
I
E
K
--
K
D
V
I
K
D
I
--------------
10
PsiBlast_PDB
52.82
43%
-180
- C2 -
-
3TRC
-
?
A:
[7-168]
--------------------------------
L
K
I
L
R
Q
I
T
Q
E
V
N
A
A
P
N
L
E
Q
A
L
K
L
V
V
V
R
L
C
E
A
L
P
A
D
A
C
S
L
F
I
C
D
D
V
----
H
G
E
Y
V
L
M
A
T
Q
-----------------
G
L
N
S
K
Q
V
G
K
L
R
L
K
F
G
E
G
L
I
G
L
V
G
E
R
E
E
P
I
N
L
A
D
A
P
---
L
H
P
A
Y
K
H
R
P
E
L
G
---------
E
E
D
Y
H
G
F
L
G
I
P
I
I
E
Q
G
E
L
L
G
I
L
V
I
Q
Q
L
E
S
H
H
F
A
E
E
E
E
A
F
C
V
T
L
A
I
H
L
A
A
E
I
A
H
A
R
A
K
G
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
50.23
19%
20
- C1 -
-
1JDE
-
PPDK_CLOSY
A:
[1-873]
AKWVYKFEEGNASMRNLLGGA
G
C
N
L
A
E
M
T
I
L
G
M
P
I
P
Q
G
F
T
V
T
T
E
A
C
T
E
Y
Y
N
S
G
K
Q
I
T
Q
E
I
Q
D
Q
I
F
E
A
I
T
W
L
E
E
L
N
G
K
K
F
GD
T
E
D
P
L
L
V
S
V
R
S
G
A
RASMPG
M
M
D
T
I
L
NL
G
L
N
D
V
A
V
E
G
F
A
K
K
T
G
N
P
R
F
A
Y
D
S
Y
R
R
F
I
Q
M
Y
S
D
V
V
MEV
P
K
S
H
F
E
K
I
I
D
A
M
KEEKGVHFD
T
D
L
T
A
D
D
L
K
E
L
A
E
K
F
K
A
V
Y
K
E
A
M
N
G
E
E
F
P
Q
E
P
K
D
Q
L
M
G
A
V
K
A
V
F
R
S
W
D
N
P
R
A
I
V
Y
R
R
M
N
---
D
I
P
G
D
W
G
T
A
V
N
V
Q
T
M
V
F
G
N
K
G
E
T
S
G
T
G
V
A
F
T
R
N
P
S
T
G
E
KGIYG
E
Y
L
I
N
--
A
Q
G
E
D
V
VAGVRT
P
Q
P
I
T
Q
L
E
N
D
M
P
D
C
Y
K
Q
F
M
D
L
A
M
K
L
E
K
H
F
R
D
M
Q
D
M
E
F
T
IEEGK
L
Y
F
L
Q
T
R
NG
K
R
T
A
P
A
A
L
Q
I
A
C
D
L
V
D
-
E
G
M
I
T
E
E
E
A
V
V
R
I
--
E
A
K
S
L
D
Q
L
L
H
P
T
F
N
P
A
A
L
K
A
G
E
V
I
G
S
A
L
PA
S
P
G
A
A
A
G
K
V
-
Y
F
-
T
A
D
E
A
K
-
A
A
H
E
K
G
E
R
V
I
L
V
R
L
E
T
S
P
E
D
I
E
G
M
H
A
--
A
E
G
I
L
T
V
R
G
G
M
T
S
H
A
A
V
V
A
R
G
M
G
T
C
C
V
S
G
C
G
E
I
K
------------
I
N
E
E
A
K
T
F
E
L
G
G
H
T
F
A
E
G
D
Y
I
S
L
D
G
S
T
G
K
I
E
T
Q
E
A
S
V
S
G
S
F
E
R
I
M
V
W
A
D
K
F
R
------
T
-
L
K
V
R
T
N
A
D
T
P
E
D
T
L
N
A
V
K
L
G
A
E
G
I
G
L
C
R
T
E
H
M
F
F
E
A
D
R
----------
I
M
-----------
K
I
R
K
M
I
L
SDS
V
E
A
R
E
E
A
L
N
E
L
I
P
-----------
F
Q
K
G
D
F
K
A
M
Y
K
A
L
E
G
R
P
M
T
V
R
Y
L
D
P
P
L
H
E
F
V
P
HT
E
E
E
Q
A
E
L
A
K
N
M
GLT
L
A
E
V
K
A
K
V
------------------------
D
------------------------
E
-
L
-
H
E
F
-
N
P
M
M
G
H
R
G
C
R
L
A
V
T
Y
P
E
I
A
K
M
Q
T
R
A
V
M
E
A
A
I
-----
E
----
V
K
---
E
E
TG
I
D
I
V
P
E
I
M
I
P
L
V
G
E
K
K
E
L
K
F
V
K
D
V
V
V
E
V
A
E
Q
V
K
-
K
-
E
K
G
S
D
M
-
Q
Y
-
H
I
G
T
M
I
E
I
P
R
A
A
L
T
A
D
A
I
A
E
E
A
E
F
F
S
F
G
T
N
D
L
T
Q
M
T
F
G
F
S
R
D
D
A
G
--
K
-
F
--
L
--------
D
-------
S
-------
Y
Y
K
A
KIYESDPFARLD
Q
T
G
V
G
Q
L
V
E
M
A
V
K
K
G
R
Q
------
T
--
R
P
------
G
L
K
C
G
I
C
G
E
H
G
G
D
P
S
S
V
E
F
C
H
K
V
G
L
N
Y
V
S
C
S
P
F
R
V
P
I
A
R
L
A
A
A
Q
A
A
L
N
N
---------
K
-----------------------------------------
25
HHSearch
49.54
26%
-14
- C1 -
-
1KBL
-
PPDK_CLOSY
A:
[418-871]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
G
E
R
V
I
L
V
R
L
E
T
S
P
E
D
I
E
G
M
H
--
A
A
E
G
I
L
T
V
R
G
G
M
T
S
H
A
A
V
V
A
R
G
M
G
T
C
C
V
S
G
C
G
E
I
K
INEEAK
T
F
E
L
GG
H
T
F
A
E
G
D
Y
I
S
L
D
G
S
T
G
K
I
Y
K
G
D
I
E
T
Q
E
A
S
V
S
G
S
F
--------------
E
R
I
M
V
W
A
D
K
F
R
T
L
K
V
R
T
N
A
D
T
P
E
D
T
L
N
A
V
K
L
G
A
E
G
I
G
L
C
R
T
E
H
M
F
F
E
A
D
R
----------
I
M
K
I
R
K
M
I
L
SD--
S
--------------------
V
E
A
R
E
E
A
L
N
E
L
I
P
F
Q
K
G
D
F
K
A
M
Y
K
A
L
E
G
R
P
M
T
V
R
Y
L
D
P
P
L
H
E
F
V
P
-----------------------
H
------------------------
T
E
E
E
Q
A
E
L
A
K
N
M
GLT
L
A
E
V
K
A
K
V
--
D
E
L
-
H
E
F
-
N
P
M
M
G
H
R
G
C
R
L
A
V
T
Y
P
E
I
A
K
M
Q
T
R
A
V
M
E
A
A
I
-----
E
V
K
E
E
T
G
I
D
I
V
-------
P
E
I
M
I
P
L
V
G
E
K
K
E
L
K
F
V
K
D
V
V
V
E
V
A
E
Q
V
K
-
K
-
E
K
G
-
S
D
M
Q
Y
-
H
I
G
T
M
I
E
I
P
R
A
A
L
T
A
D
A
I
A
E
E
A
E
F
F
S
F
G
T
N
D
L
T
Q
M
T
F
G
F
S
R
D
D
A
G
KF
L
-
D
--
S
--------
Y
-------
Y
K
A
KIYES
D
P
F
ARLD---------
Q
T
G
V
G
Q
L
V
E
M
A
V
K
K
G
R
Q
T
R----
P
--
G
L
------
K
--
C
G
I
C
G
E
H
G
G
D
P
S
S
V
E
F
C
H
K
V
G
L
N
Y
V
S
C
S
P
F
R
V
P
I
A
R
L
A
A
A
Q
A
A
L
N
----------------------------------------------------
24
HHSearch
49.53
28%
-20
- C1 -
-
1VBG
-
PPDK1_MAIZE
A:
[422-874]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
G
K
A
A
I
L
V
R
A
E
T
S
P
E
D
V
G
G
M
H
--
A
A
V
G
I
L
T
E
R
G
G
M
T
S
H
A
A
V
V
A
R
G
W
G
K
C
C
V
S
G
C
S
G
I
R
VNDAEK
L
V
T
I
GG
H
V
L
R
E
G
E
W
L
S
L
N
G
S
T
G
E
V
I
L
G
K
Q
P
L
S
P
P
A
L
S
G
D
L
-------------
G
T
F
M
A
W
V
D
D
V
R
K
-
L
K
V
L
A
N
A
D
T
P
D
D
A
L
T
A
R
N
N
G
A
Q
G
I
G
L
C
R
T
E
H
M
F
F
A
S
D
E
R
I
K
A
V
R
Q
M
I
M
A
P
-----------
T
--------------------
L
E
L
R
Q
Q
A
L
D
R
L
L
P
Y
Q
R
S
D
F
E
G
I
F
R
A
M
D
G
L
P
V
T
I
R
L
L
D
P
P
L
H
E
F
L
P
-----------------------
E
------------------------
G
N
I
E
D
I
V
S
E
L
C
A
E
TGAN
Q
E
D
A
L
A
R
I
E
-
K
L
S
E
V
-
N
P
M
L
G
F
R
G
C
R
L
G
I
S
Y
P
E
L
T
E
M
Q
A
R
A
I
F
E
A
A
I
-----
A
M
T
N
-
Q
G
VQV
F
-------
P
E
I
M
V
P
L
V
G
T
P
Q
E
L
G
H
Q
V
T
L
I
R
Q
V
A
E
K
V
F
---
A
N
V
G
K
T
I
G
Y
-
K
V
G
T
M
I
E
I
P
R
A
A
L
V
A
D
E
I
A
E
Q
A
E
F
F
S
F
G
T
N
D
L
T
Q
M
T
F
G
Y
S
R
D
D
V
G
--
K
F
I
--
P
V
Y
L
A
Q
GIL
Q
-------
H
-------
D
P
F
-------------
E
V
L
D
Q
R
G
V
G
E
L
V
K
F
A
T
E
R
G
R
K
A
R
P
--
N
L
------
K
--
V
G
I
C
G
E
H
G
G
E
P
S
S
V
A
F
F
A
K
A
G
L
D
Y
V
S
C
S
P
F
R
V
P
I
A
R
L
A
A
A
Q
V
-------------------------------------------------------
23
HHSearch
49.28
25%
-
- C1 -
-
2X0S
-
?
A:
[446-899]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
G
K
K
V
I
M
V
R
L
E
T
S
P
E
D
L
A
G
M
D
--
A
A
C
G
I
L
T
A
R
G
G
M
T
S
H
A
A
V
V
A
R
G
M
G
K
C
C
V
S
G
C
G
D
M
V
I
R
G
KSFKLNG--
S
V
F
R
E
G
D
Y
I
T
I
D
G
S
K
G
L
I
Y
A
G
K
L
K
L
R
S
P
D
L
K
G
S
F
Q
T
I
-------------
L
Q
W
C
Q
E
M
K
R
-
L
G
V
R
T
N
A
D
T
P
A
D
A
A
K
A
R
S
F
G
A
E
G
V
G
L
C
R
T
E
H
M
F
F
E
G
S
R
----------
I
N
F
I
R
E
M
I
L
ADSA
S
GR
K
A
A
L
D
K
L
-----------
L
P
-----------
I
Q
R
A
D
F
V
G
I
L
R
A
M
R
G
L
P
V
T
I
R
L
L
D
P
P
L
H
E
F
V
P
-----------------------
H
DAAAQFELAQKLGMPAEK
V
R
N
R
--
V
------------------------
N
-
A
L
H
E
L
-
N
P
M
L
G
H
R
G
C
R
L
G
I
T
Y
P
E
I
Y
N
M
Q
V
R
A
I
I
E
A
A
I
A
V
S
E
E
G
S
---
S
V
---
I
-------
P
E
I
M
V
P
L
V
G
K
K
E
E
L
S
L
I
R
E
E
V
V
K
T
A
E
A
V
I
T
K
-
S
G
K
R
--
V
H
Y
-
T
V
G
T
M
I
E
V
P
R
A
A
V
T
A
D
S
I
A
Q
K
A
D
F
F
S
F
G
T
N
D
L
T
Q
M
G
C
G
F
S
R
D
D
A
G
PF
L
-
R
--
H
--------
Y
G
N
L
GIYA
Q
-------
D
P
F
-------------
Q
S
I
D
Q
E
G
I
G
E
L
V
R
I
A
V
T
------
K
--
G
R
R
V
KPM
L
K
--
M
G
I
C
G
E
H
G
G
D
P
A
T
I
G
F
C
H
K
V
G
L
D
Y
V
S
C
S
P
F
R
V
P
V
A
I
V
A
A
A
H
A
S
I
K
D
---------
R
R
----------------------------------------
11
PsiBlast_PDB
48.09
33%
-150
- C1 -
-
5T1O
-
PT1P_ECOLI
B:
[44-249]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
G
A
L
E
E
A
A
N
E
F
R
R
Y
S
K
R
F
A
A
G
A
Q
K
E
T
A
A
I
F
D
-----
L
Y
S
H
L
L
S
--
D
T
R
L
R
R
E
L
F
---
A
E
V
D
-
K
G
S
V
-
A
E
W
A
V
K
T
V
I
E
K
F
A
E
Q
F
A
A
L
S
D
N
Y
L
K
E
R
A
G
D
L
R
A
L
G
Q
R
L
----------
L
-
F
H
-
L
D
D
A
N
Q
-
G
P
N
A
W
P
E
R
F
I
L
V
A
D
E
L
S
A
T
T
L
A
E
L
P
Q
D
R
L
V
G
V
V
V
R
D
G
A
A
N
S
Q
A
A
I
M
V
R
A
L
G
I
P
T
V
M
G
A
D
I
Q
P
-------------
S
V
L
H
R
R
T
L
I
V
D
G
Y
R
G
E
L
L
V
D
P
E
P
V
L
L
Q
E
Y
Q
R
L
I
S
E
E
I
E
L
S
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
47.77
25%
-6
- C1 -
-
5JVL
1
PPDK_FLATR
D:
[420-872]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
K
S
A
I
L
V
R
T
E
T
S
P
E
D
V
G
G
M
H
--
A
A
A
G
I
L
T
A
R
G
G
M
T
S
H
A
A
V
V
A
R
G
W
G
K
C
C
V
S
G
C
A
D
I
R
VNDDMKIFTIGD
R
V
I
K
E
G
D
W
L
S
L
N
G
T
T
G
E
V
I
L
G
K
Q
L
L
A
P
P
A
M
S
N
D
L
-------------
E
I
F
M
S
W
A
D
Q
A
R
R
-
L
K
V
M
A
N
A
D
T
P
N
D
A
L
T
A
R
N
N
G
A
Q
G
I
G
L
C
R
T
E
H
M
F
F
A
S
D
E
RIKAVRKMIM
A
V
-----------
T
--------------------
P
E
QRKVALDLLLP
Y
Q
R
S
D
F
E
G
I
F
R
A
M
D
G
L
P
V
T
I
R
L
L
D
P
P
L
H
E
F
L
P
-----------------------
E
GDLEHIVNELAVDTGMSADEIYSK
I
------------------------
E
-
N
L
S
E
V
-
N
P
M
L
G
F
R
G
C
R
L
G
I
S
Y
P
E
L
T
E
M
Q
V
R
A
I
F
Q
A
A
V
-----
S
MTN-
Q
G
VTV
I
-------
P
E
I
M
V
P
L
V
G
T
P
Q
E
L
R
H
Q
I
S
V
I
R
G
V
A
A
N
V
F
-
A
E
M
G
V
T
--
L
E
Y
-
K
V
G
T
M
I
E
I
P
R
A
A
L
I
A
E
E
I
G
K
E
A
D
F
F
S
F
G
T
N
D
L
T
Q
M
T
F
G
Y
S
R
D
D
V
G
--
K
-
F
LQ
I
--------
Y
LAQGILQ
H
-------
D
P
F
EVID---------
Q
K
G
V
G
Q
L
I
K
M
A
T
E
K
G
R
A
------
A
NP
S
L
------
K
--
V
G
I
C
G
E
H
G
G
E
P
S
S
V
A
F
F
D
G
V
G
L
D
Y
V
S
C
S
P
F
R
V
P
I
A
R
L
A
A
A
Q
V
-------------------------------------------------------