@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLC0: (2017-11-01 )
MSLKTELVIFDWDGTLYNSVGQIVASLQHAAEEHKLTLTDEAAKSIIGLGLPEVMQTLFPEVPDLHDSILKAYGDHYIANSTNDAWFEGISELLHDLKAQGLKLAVATGKNRRGLDRVIAKTQSTHLFDVTRAANETRSKPDPLMLQEILTVTGVSVEQAVMIGDSSYDLEMAQRLGMPRIGVGYGVHSVEVLQQFQPLTIAKDVSELHNFLREYAKLSTVDVA
Atome Classification :
(20 SA)
.........10........20........30..--....-.-.40..-.......----50----------------------------...-......------60.--.---------.--------.....----70......-..80-..-.-..-....90........100.......-110.......120..--....--.-130-...---.--..-----.-140.......150....-...160.......170.......180.....-...190--.........200.......210.......220..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSL
K
T
E
L
V
I
F
DWD
G
T
L
Y
N
S
V
G
Q
I
V
A
S
L
Q
H
A
A
E
E--H
K
L
T
-L-
T
D
-
E
A
-
A
K
S
I
I
GL----G-----------------------------
L
P
E
-
V
M
Q
T
LF------PEV--P---------
D
--------
L
H
D
S
I
----
L
K
A
YGD
H
Y
-IAN--ST-
N
-
D
A
-
W
F
E
G
I
S
E
L
L
H
D
L
K
AQG
L
K
L
A
V
ATG-KNRR
G
L
D
R
V
I
A
KTQS--
T
H
L
F
--
D
-
V
T
R-AAN---E--TR-----S-KP
D
P
L
M
L
Q
E
I
L
T
VTGVS-
V
E
Q
A
V
M
IGDSSY
D
L
E
M
A
Q
RLGMPRI-GVGYG-
V
H
S
V
----
E
V
L
Q
QFQP
L
T
I
A
K
D
V
S
E
L
H
N
F
L
R
E
Y
AKLSTVDVA
25
HHSearch
80.33
23%
-29
- C1 -
-
3SD7
3
?
A:
[26-239]
-
K
K
N
Y
E
I
V
L
F
D
L
D
G
T
L
T
D
P
K
E
G
I
T
K
S
I
Q
Y
S
L
N
S
--
F
G
I
K
-
E
-
D
L
-
E
N
-
L
D
Q
F
I
G
P
----
P
-----------------------------
L
H
D
-
T
F
K
E
Y
Y
------
K
F
E
--
D
---------
K
--------
K
A
K
E
A
----
V
E
K
Y
R
E
Y
F
-
A
D
K
--
G
I
F
E
-
N
K
-
I
Y
E
N
M
K
E
I
L
E
M
L
Y
K
N
G
K
I
L
L
V
A
T
S
-
K
P
T
V
F
A
E
T
I
L
R
Y
F
D
I
--
D
R
Y
F
--
K
-
Y
I
A
-
G
S
N
---
L
D-
G
T
-----
R
-
V
N
K
N
E
V
I
Q
Y
V
L
D
L
C
N
V
K
D
K
D
K
V
I
M
V
G
D
R
K
Y
D
I
I
G
A
K
K
I
G
I
D
S
I
-
G
V
L
Y
G
-
Y
G
S
F
----
E
E
I
S
E
S
E
P
T
Y
I
V
E
N
V
E
S
I
K
D
I
L
------------
6
PsiBlast_PDB
79.97
25%
-14
- C1 -
-
2HSZ
1
?
A:
[24-238]
-----
K
L
I
G
F
D
L
D
G
T
L
V
N
S
L
P
D
L
A
L
S
I
N
S
A
L
K
D
--
V
N
L
P
-
Q
-
A
S
-
E
N
L
V
M
T
W
I
G
N
----
G
-----------------------------
A
D
V
-
L
S
Q
R
A
V
------
D
W
A
--
C
K
Q
A
E
K
E
L
T
E
D
--------
E
F
K
Y
F
----
K
R
Q
F
G
F
Y
Y
-
G
E
N
--
L
C
-
N
I
S
R
-
L
Y
P
N
V
K
E
T
L
E
A
L
K
A
Q
G
Y
I
L
A
V
V
T
N
-
K
P
T
K
H
V
Q
P
I
L
T
A
F
G
I
--
D
H
L
F
--
S
-
E
M
L
-
G
G
Q
---
S
L-
P
E
-----
I
-
K
P
H
P
A
P
F
Y
Y
L
C
G
K
F
G
L
Y
-
P
K
Q
I
L
F
V
G
D
S
Q
N
D
I
F
A
A
H
S
A
G
C
A
V
V
-
G
L
T
Y
G
-
Y
N
Y
N
----
I
P
I
A
Q
S
K
P
D
W
I
F
D
D
F
A
D
I
----------------
10
PsiBlast_PDB
79.47
27%
11
- C1 -
-
3D6J
1
?
A:
[5-210]
---
K
Y
T
V
Y
L
F
D
F
D
Y
T
L
A
D
S
S
R
G
I
V
T
C
F
R
S
V
L
E
R
--
H
G
Y
T
G
I
-
T
D
-
D
M
-
I
K
R
T
I
G
K
----
T
-----------------------------
L
E
E
-
S
F
S
I
L
T
------
G
I
T
D-
A
---------
D
--------
Q
L
E
S
F
----
R
Q
E
Y
S
K
E
A
D
I
Y
M
--
N
A
-
N
-
T
I
-
L
F
P
D
T
L
P
T
L
T
H
L
K
K
Q
G
I
R
I
G
I
I
S
T
-
K
Y
R
F
R
I
L
S
F
L
R
N
H
M
P
--
D
D
W
F
--
D
-
I
I
I
-
G
G
E
---
D
V-
T
H
-----
H
-
K
P
D
P
E
G
L
L
L
A
I
D
R
L
K
A
C
-
P
E
E
V
L
Y
I
G
D
S
T
V
D
A
G
T
A
A
A
A
G
V
S
F
T
-
G
V
T
S
G
-
M
T
T
A
-------
Q
E
F
Q
A
Y
P
Y
D
R
I
I
S
T
L
----------------
5
PsiBlast_PDB
77.91
24%
-10
- C1 -
-
3SD7
3
?
A:
[26-239]
-
K
K
N
Y
E
I
V
L
F
D
L
D
G
T
L
T
D
P
K
E
G
I
T
K
S
I
Q
Y
S
L
N
S
--
F
G
I
K
-
E
-
D
L
-
E
N
-
L
D
Q
F
I
G
P
----
P
-----------------------------
L
H
D
-
T
F
K
E
Y
Y
------
K
F
E
--
D
---------
K
--------
K
A
K
E
A
----
V
E
K
Y
R
E
Y
F
-
A
D
K
--
G
I
F
E
-
N
K
-
I
Y
E
N
M
K
E
I
L
E
M
L
Y
K
N
G
K
I
L
L
V
A
T
S
-
K
P
T
V
F
A
E
T
I
L
R
Y
F
D
I
--
D
R
Y
F
--
K
-
Y
I
A
-
G
S
N
LD-
G
--
T
R
-----
V
-
N
K
N
E
V
-
I
Q
Y
V
L
D
L
C
N
V
K
D
K
D
K
V
I
M
V
G
D
R
K
Y
D
I
I
G
A
K
K
I
G
I
D
S
I
-
G
V
L
Y
G
-
Y
G
S
F
----
E
E
I
S
E
S
E
P
T
Y
I
V
E
N
V
E
S
I
K
D
I
L
------------
27
HHSearch
77.77
25%
1
* C1 *
-
4EX6
1
?
A:
[17-235]
--
A
A
D
R
G
V
I
L
D
L
D
G
T
L
A
D
T
P
A
A
I
A
T
I
T
A
E
V
L
A
A
--
M
G
T
A
-
V
-
S
R
-
G
A
-
I
L
S
T
V
G
R
----
P
-----------------------------
L
P
A
-
S
L
A
G
L
L
------
G
V
P
--
V
ED-------
P
--------
R
V
A
E
A
----
T
E
E
Y
G
R
R
F
-
G
A
H
V
R
A
A
G
P
-
R
L
-
L
Y
P
G
V
L
E
G
L
D
R
L
S
A
A
G
F
R
L
A
M
A
T
S
-
K
V
E
K
A
A
R
A
I
A
E
L
T
G
L
--
D
T
R
L
--
T
-
V
I
A
-
G
D
D
---
S
V-
E
R
-----
G
-
K
P
H
P
D
M
A
L
H
V
A
R
G
L
G
I
P
-
P
E
R
C
V
V
I
G
D
G
V
P
D
A
E
M
G
R
A
A
G
M
T
V
I
-
G
V
S
Y
G
-
V
S
G
P
----
D
E
L
M
R
A
G
A
D
T
V
V
D
S
F
P
A
A
V
T
A
V
L
D
G
---------
26
HHSearch
76.39
25%
6
- C1 -
-
3D6J
1
?
A:
[5-214]
---
K
Y
T
V
Y
L
F
D
F
D
Y
T
L
A
D
S
S
R
G
I
V
T
C
F
R
S
V
L
E
R
--
H
G
Y
T
-
G
I
T
D
-
D
M
-
I
K
R
T
I
G
K
----
T
-----------------------------
L
E
E
-
S
F
S
I
L
T
------
G
I
T
--
D
A
--------
D
--------
Q
L
E
S
F
----
R
Q
E
Y
S
K
E
A
-
D
I
Y
--
M
N
A
N
-
T
I
-
L
F
P
D
T
L
P
T
L
T
H
L
K
K
Q
G
I
R
I
G
I
I
S
T
-
K
Y
R
F
R
I
L
S
F
L
R
N
H
M
P
--
D
D
W
F
--
D
-
I
I
I
-
G
G
E
---
D
V-
T
H
-----
H
-
K
P
D
P
E
G
L
L
L
A
I
D
R
L
K
A
C
-
P
E
E
V
L
Y
I
G
D
S
T
V
D
A
G
T
A
A
A
A
G
V
S
F
T
-
G
V
T
S
G
-
M
T
T
A
----
Q
E
F
Q
A
Y
P
Y
D
R
I
I
S
T
L
G
Q
L
I
---------------
24
HHSearch
75.92
24%
13
- C1 -
-
3MC1
1
?
A:
[2-217]
--
S
L
Y
N
Y
V
L
F
D
L
D
G
T
L
T
D
S
A
E
G
I
T
K
S
V
K
Y
S
L
N
K
--
F
D
I
Q
-
V
E
D
L
-
S
S
-
L
N
K
F
V
G
P
----
P
-----------------------------
L
K
T
-
S
F
M
E
Y
Y
------
N
F
D
--
E
---------
E
--------
T
A
T
V
A
----
I
D
Y
Y
R
D
Y
F
-
K
A
K
--
G
M
F
E
-
N
K
-
V
Y
D
G
I
E
A
L
L
S
S
L
K
D
Y
G
F
H
L
V
V
A
T
S
-
K
P
T
V
F
S
K
Q
I
L
E
H
F
K
L
--
A
F
Y
F
--
D
-
A
I
V
-
G
S
S
---
L
D-
G
K
-----
L
-
S
T
K
E
D
V
I
R
Y
A
M
E
S
L
N
I
K
-
S
D
D
A
I
M
I
G
D
R
E
Y
D
V
I
G
A
L
K
N
N
L
P
S
I
-
G
V
T
Y
G
-
F
G
S
Y
----
E
E
L
K
N
A
G
A
N
Y
I
V
N
S
V
D
E
L
H
K
K
I
L
E
L
---------
35
HHSearch
74.58
25%
5
- C1 -
-
3KBB
4
P1254_THEMA
A:
[1-214]
----
M
E
A
V
I
F
D
M
D
G
V
L
M
D
T
E
P
L
Y
F
E
A
Y
R
R
V
A
E
S
--
Y
G
K
P
-
Y
-
T
E
-
D
L
-
H
R
R
I
M
G
V
----
P
-----------------------------
E
R
E
-
G
L
P
I
L
M
------
E
A
L
--
E
I
K
-------
D
--------
S
L
E
N
F
----
K
K
R
V
H
E
E
K
-
K
R
V
--
F
S
E
L
-
L
K
-
E
N
P
G
V
R
E
A
L
E
F
V
K
S
K
R
I
K
L
A
L
A
T
S
-
T
P
Q
R
E
A
L
E
R
L
R
R
L
D
L
--
E
K
Y
F
--
D
-
V
M
V
-
F
G
D
---
Q
V-
K
N
-----
G
-
K
P
D
P
E
I
Y
L
L
V
L
E
R
L
N
V
V
-
P
E
K
V
V
V
F
E
D
S
K
S
G
V
E
A
A
K
S
A
G
I
E
R
I
Y
G
V
V
H
S
-
L
N
D
G
----
K
A
L
L
E
A
G
A
V
A
L
V
-
K
P
E
E
I
L
N
V
L
K
E
----------
44
HHSearch
74.32
23%
-10
- C1 -
-
4EEK
-
?
A:
[25-249]
-
D
A
P
F
D
A
V
L
F
D
L
D
G
V
L
V
E
S
E
G
I
I
A
Q
V
W
Q
S
V
L
A
E
--
R
G
L
H
-
L
-
D
L
T
E
I
-
A
M
Y
F
T
G
Q
----
R
-----------------------------
F
D
G
-
V
L
A
Y
L
A
------
Q
Q
H
--
D
F
--------
V
--------
P
P
P
D
F
----
L
D
V
L
E
T
R
F
-
N
A
A
---
M
T
G
-
V
T
-
A
I
E
G
A
A
E
T
L
R
A
L
R
A
A
G
V
P
F
A
I
G
S
N
-
S
E
R
G
R
L
H
L
K
L
R
V
A
G
L
--
T
E
L
A
--
G
-
E
H
I
Y
D
P
S
---
W
VG
G
R
-----
G
-
K
P
H
P
D
L
Y
T
F
A
A
Q
Q
L
G
I
L
-
P
E
R
C
V
V
I
E
D
S
V
T
G
G
A
A
G
L
A
A
G
A
T
L
W
-
G
L
L
V
P
-
G
H
P
H
PDG
A
A
A
L
S
R
L
G
A
A
R
V
L
T
S
H
A
E
L
R
A
A
L
A
E
A
G
L
-------
9
PsiBlast_PDB
73.12
28%
-26
- C1 -
-
3KBB
4
P1254_THEMA
A:
[2-188]
-----
E
A
V
I
F
D
M
D
G
V
L
M
D
T
E
P
L
Y
F
E
A
Y
R
R
V
A
E
S
--
Y
G
K
P
-
Y
-
T
E
-
D
L
-
H
R
R
I
M
G
V
PER
E
G
-----------------------------
L
P
I
-
L
M
E
A
L
--------
E
I
--
K
---------
D
S
L
E
N
F
K
K
R
V
H
E
E
K
----
K
R
V
F
S
E
L
L
-
K
E
N
--
P
----------
G
V
R
E
A
L
E
F
V
K
S
K
R
I
K
L
A
L
A
T
S
T
P
Q
R
E
A
L
E
R
-
L
R
R
L
D
L
--
E
K
Y
F
--
D
-
V
M
V
-
F
G
D
---
Q
--
V
K
-----
N
G
K
P
D
P
E
I
Y
L
L
V
L
E
R
L
N
V
V
-
P
E
K
V
V
V
F
E
D
S
K
S
G
V
E
A
A
K
S
A
G
I
E
R
I
----
Y
G
V
V
H
S
L
--------------------------------------
45
Fugue
72.43
20%
-96
- C1 -
-
2FI1
-
?
A:
[4-190]
--
M
K
Y
H
D
Y
I
W
D
L
G
G
T
L
L
D
N
Y
E
T
S
T
A
A
F
V
E
T
L
A
L
--
Y
G
I
T
-
Q
-
D
H
-
D
S
-
V
Y
Q
A
L
K
V
----
S
-----------------------------
T
P
F
-
A
I
E
T
F
A
------
P
N
-----------------------
L
E
N
F
----
L
E
K
Y
K
E
N
E
-
A
R
E
--
L
E
-
H
-
P
I
-
L
F
E
G
V
S
D
L
L
E
D
I
S
N
Q
G
G
R
H
F
L
V
S
H
-
R
N
D
-
Q
V
L
E
I
L
E
K
T
S
I
--
A
A
Y
F
--
T
-
E
V
V
-
T
S
S
---
S
G-
F
K
-----
R
-
K
P
N
P
E
S
M
L
Y
L
R
E
K
Y
Q
I
---
S
S
G
L
V
I
G
D
R
P
I
D
I
E
A
G
Q
A
A
G
L
D
T
H
-
L
F
T
S
I
-
V
N
L
R
----
Q
V
L
D
I
-----------------------------
2
PsiBlast_PDB
72.34
29%
14
- C1 -
-
4EX6
1
?
A:
[22-215]
-------
V
I
L
D
L
D
G
T
L
A
D
T
P
A
A
I
A
T
I
T
A
E
V
L
A
A
--
M
G
T
A
-
V
-
S
R
-
G
A
-
I
L
S
T
V
G
R
----
P
-----------------------------
L
P
A
-
S
L
A
G
L
L
GVPVED
P
R
V
--
A
---------
E
--------
A
T
E
E
Y
----
G
R
R
F
G
A
H
V
-
R
A
A
--
G
P
-
R
--
L
-
L
Y
P
G
V
L
E
G
L
D
R
L
S
A
A
G
F
R
L
A
M
A
T
S
-
K
V
E
K
A
A
-
R
A
I
A
E
L
T
G
LD
T
R
L
T
--
V
-
I
A
G
-
D
D
S
---
V
--
E
R
-----
G
-
K
P
H
P
D
M
A
L
H
V
A
R
G
L
G
I
P
-
P
E
R
C
V
V
I
G
D
G
V
P
D
A
E
M
G
R
A
A
G
M
T
V
I
-
G
V
S
Y
G
-
V
S
G
P
----
D
E
L
M
R
-----------------------------
3
PsiBlast_PDB
72.31
29%
15
- C1 -
-
4EX7
1
?
A:
[22-215]
-------
V
I
L
D
L
D
G
T
L
A
D
T
P
A
A
I
A
T
I
T
A
E
V
L
A
A
--
M
G
T
A
-
V
-
S
R
-
G
A
-
I
L
S
T
V
G
R
----
P
-----------------------------
L
P
A
-
S
L
A
G
L
L
GVPVED
P
R
V
--
A
---------
E
--------
A
T
E
E
Y
----
G
R
R
F
G
A
H
V
-
R
A
A
--
G
P
-
R
--
L
-
L
Y
P
G
V
L
E
G
L
D
R
L
S
A
A
G
F
R
L
A
M
A
T
S
-
K
V
E
K
A
A
-
R
A
I
A
E
L
T
G
LD
T
R
L
T
--
V
-
I
A
G
-
D
D
S
---
V
--
E
R
-----
G
-
K
P
H
P
D
M
A
L
H
V
A
R
G
L
G
I
P
-
P
E
R
C
V
V
I
G
D
G
V
P
D
A
E
M
G
R
A
A
G
M
T
V
I
-
G
V
S
Y
G
-
V
S
G
P
----
D
E
L
M
R
-----------------------------
41
HHSearch
71.67
23%
5
- C1 -
-
3QU5
-
?
B:
[21-241]
-
R
K
K
L
K
A
V
L
F
N
M
D
G
V
L
F
N
S
M
P
Y
H
S
E
A
W
H
Q
V
M
K
T
--
H
G
L
D
-
L
-
S
R
-
E
E
-
A
Y
M
H
E
G
R
----
T
-----------------------------
G
A
S
-
T
I
N
I
V
F
------
Q
R
E
L-
G
K
E
-------
A
--------
T
Q
E
E
I
----
E
S
I
Y
H
E
K
S
-
I
L
F
N
-
S
Y
P
E
-
A
E
-
R
M
P
G
A
W
E
L
L
Q
K
V
K
S
E
G
L
T
P
M
V
V
T
G
-
S
G
Q
L
S
L
L
E
R
L
E
H
N
-
F
--
P
G
M
F
HK
E
-
L
M
V
-
T
A
F
---
D
V-
K
Y
-----
G
-
K
P
N
P
E
P
Y
L
M
A
L
K
K
G
G
L
K
-
A
D
E
A
V
V
I
E
N
A
P
L
G
V
E
A
G
H
K
A
G
I
F
T
I
-
A
V
N
T
G
-
P
L
D
G
----
Q
V
L
L
D
A
G
A
D
L
L
F
P
S
M
Q
T
L
C
D
S
W
D
T
I
---------
12
PsiBlast_PDB
71.39
24%
-4
- C1 -
-
2AH5
-
?
A:
[7-210]
-------
I
F
F
D
L
D
G
T
L
V
D
S
S
I
G
I
H
N
A
F
T
Y
T
F
K
E
----
L
G
-
V
-
P
S
-
P
D
-
A
K
T
I
R
G
F
----
M
-----------------------------
G
P
P
-
L
E
S
S
F
A
------
T
C
L
--
S
K--------
D
--------
Q
I
S
E
A
----
V
Q
I
Y
R
S
Y
Y
-
K
A
K
--
G
I
-
Y
-
E
A
Q
L
F
P
Q
I
I
D
L
L
E
E
L
S
S
-
S
Y
P
L
Y
I
T
T
T
-
K
D
T
S
T
A
Q
D
M
A
K
N
L
E
I
--
H
H
F
F
--
D
G
I
Y
G
-
S
S
P
---
E
--
A
P
-----
H
-
K
A
D
--
V
I
H
Q
A
L
Q
T
H
Q
L
A
-
P
E
Q
A
I
I
I
G
D
T
K
F
D
M
L
G
A
R
E
T
G
I
Q
K
L
-
A
I
T
W
G
-
F
G
E
Q
----
A
D
L
L
N
Y
Q
P
D
Y
I
A
H
K
P
L
E
V
L
A
Y
F
Q
-----------
34
HHSearch
70.51
23%
5
- C1 -
-
3S6J
-
?
E:
[5-224]
---
P
Q
T
S
F
I
F
D
L
D
G
T
L
T
D
S
V
Y
Q
N
V
A
A
W
K
E
A
L
D
A
--
E
N
I
P
-
L
-
A
M
-
W
R
-
I
H
R
K
I
G
M
----
S
-----------------------------
G
G
L
-
M
L
K
S
L
S
------
R
E
T
--
G
M
S
I
T
D
----
E
--------
Q
A
E
R
L
----
S
E
K
H
A
Q
A
Y
-
E
R
---
L
Q
H
Q
-
I
I
-
A
L
P
G
A
V
E
L
L
E
T
L
D
K
E
N
L
K
W
C
I
A
T
S
-
G
G
I
D
T
A
T
I
N
L
K
A
L
K
L
--
D
I
N
K
--
I
-
N
I
V
-
T
R
D
---
D
V-
S
Y
-----
G
-
K
P
D
P
D
L
F
L
A
A
A
K
K
I
G
A
P
-
I
D
E
C
L
V
I
G
D
A
I
W
D
M
L
A
A
R
R
C
K
A
T
G
V
-
G
L
L
S
G
-
G
Y
D
I
----
G
E
L
E
R
A
G
A
L
R
V
Y
E
D
P
L
D
L
L
N
H
L
D
E
I
A
S
-------
33
HHSearch
69.27
23%
3
- C1 -
-
3S6J
-
?
A:
[5-224]
---
P
Q
T
S
F
I
F
D
L
D
G
T
L
T
D
S
V
Y
Q
N
V
A
A
W
K
E
A
L
D
A
--
E
N
I
P
-
L
-
A
M
-
W
R
-
I
H
R
K
I
G
M
----
S
-----------------------------
G
G
L
-
M
L
K
S
L
S
------
R
E
----IT
D
------
E
--------
Q
A
E
R
L
----
S
E
K
H
A
Q
A
Y
-
E
R
---
L
Q
H
Q
-
I
I
-
A
L
P
G
A
V
E
L
L
E
T
L
D
K
E
N
L
K
W
C
I
A
T
S
-
G
G
I
D
T
A
T
I
N
L
K
A
L
K
L
--
D
I
N
K
--
I
-
N
I
V
-
T
R
D
---
D
V-
S
Y
-----
G
-
K
P
D
P
D
L
F
L
A
A
A
K
K
I
G
A
P
-
I
D
E
C
L
V
I
G
D
A
I
W
D
M
L
A
A
R
R
C
K
A
T
G
V
-
G
L
L
S
G
-
G
Y
D
I
----
G
E
L
E
R
A
G
A
L
R
V
Y
E
D
P
L
D
L
L
N
H
L
D
E
I
A
S
-------
4
PsiBlast_PDB
68.95
26%
4
- C1 -
-
3MC1
1
?
A:
[7-211]
-------
V
L
F
D
L
D
G
T
L
T
D
S
A
E
G
I
T
K
S
V
K
Y
S
L
N
K
--
F
D
I
Q
-
V
-
E
D
-
L
S
-
S
L
N
K
F
-
V
----
G
-----------------------------
P
P
---
L
K
T
S
F
------
M
E
Y
--
Y
---------
N
--------
F
D
E
E
T
A
T
V
A
I
D
Y
Y
R
D
Y
F
-
K
A
K
--
G
M
F
E
-
N
K
-
V
Y
D
G
I
E
A
L
L
S
S
L
K
D
Y
G
F
H
L
V
V
A
T
S
-
K
P
T
V
F
S
K
Q
I
L
E
H
F
K
L
--
A
F
Y
F
--
D
-
A
I
V
-
G
S
S
LDG
K
--
L
S
-----
T
-
K
E
D
--
V
I
R
Y
A
M
E
S
L
N
I
K
-
S
D
D
A
I
M
I
G
D
R
E
Y
D
V
I
G
A
L
K
N
N
L
P
S
I
-
G
V
T
Y
G
-
F
G
S
Y
----
E
E
L
K
N
A
G
A
N
Y
I
V
N
S
V
D
E
L
H
---------------
11
PsiBlast_PDB
68.83
25%
-3
- C1 -
-
3S6J
-
?
A:
[10-223]
--------
I
F
D
L
D
G
T
L
T
D
S
V
Y
Q
N
V
A
A
W
K
E
A
L
D
A
--
E
N
I
P
-
L
-
A
M
-
W
R
-
I
H
R
K
I
G
M
----
S
-----------------------------
G
G
L
-
M
L
K
S
L
S
------
R
E
-IT
D
---------
E
--------
Q
A
E
R
L
----
S
E
K
H
A
Q
A
Y
-
E
R
L
--
Q
H
-
Q
-
I
I
-
A
L
P
G
A
V
E
L
L
E
T
L
D
K
E
N
L
K
W
C
I
A
T
S
-
G
---
G
I
D
T
A
T
I
N
L
K
A
--
L
K
L
---
D
-
I
N
K
-
I
N
I
---
V
--
T
R
DDVSY
G
-
K
P
D
P
D
L
F
L
A
A
A
K
K
I
G
A
P
-
I
D
E
C
L
V
I
G
D
A
I
W
D
M
L
A
A
R
R
C
K
A
T
G
V
-
G
L
L
S
G
-
G
Y
D
I
----
G
E
L
E
R
A
G
A
L
R
V
Y
E
D
P
L
D
L
L
N
H
L
D
E
I
A
--------
1
PsiBlast_PDB
68.04
27%
35
- C1 -
-
2HI0
5
?
A:
[3-220]
---
K
Y
K
A
A
I
F
D
M
D
G
T
I
L
D
T
S
A
D
L
T
S
A
L
N
Y
A
F
E
Q
T
G
H
R
H
D
-
F
-
T
V
-
E
D
-
I
K
N
F
F
G
S
----
G
V
V
V
A
V
T
R
A
L
A
Y
E
A
GSSRESLVAFGTKDEQ
I
P
E
A
V
T
Q
T
---------
E
V
--
N
---------
R
--------
V
L
E
V
F
----
K
P
Y
Y
A
D
H
C
------
Q
I
-
K
-
T
G
-
P
F
P
G
I
L
D
L
M
K
N
L
R
Q
K
G
V
K
L
A
V
V
S
N
-
K
P
N
E
A
V
-
Q
V
L
V
E
E
L
F
--
P
G
S
F
--
D
-
F
A
L
-
G
E
K
---
S
G-
I
R
-----
R
-
K
P
A
P
D
M
T
S
E
C
V
K
V
L
G
V
P
-
R
D
K
C
V
Y
I
G
D
S
E
I
D
I
Q
T
A
R
N
S
E
M
D
E
I
-
A
V
N
W
G
-
F
R
S
V
----
P
F
L
Q
K
-----------------------------