@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLF9: (2017-11-02 )
MSFSRKQFALSAIFVAILATGGSFMLLHENADAKAAPTAAQQAATVDVAPVVSKTITDWQEYSGRLEAIDQVDIRPQVSGKLIAVHFKDGSLVKKGDLLFTIDPRPFEAELNRAKAQLASAEAQVTYTASNLSRIQRLIQSNAVSRQELDLAENDARSANANLQAARAAVQSARLNLEYTRITAPVSGRISRAEVTVGNVVSAGNGAQVLTSLVSVSRLYASFDVDEQTYLKYISNQRNSSQVPVYMGLANETGFTREGTINSIDNNLNTTSGTIRVRATFDNPNGVLLPGLYARIRLGGGQPRPAILISPTAVGVDQDKRFVVVVDAKNQTAYREVKLGAQQDGLQIVNSGLQAGDRIVVNGLQRIRPGDPVTPHLVPMPNSQITANATPQPQPTDKTSTPAKG
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........--70........80........90........100..-------.....110.......120-----.........130.......140.......150.....-------..160-----.........170.....---------..180.......190.......200.-......--210.......220.-..-----..-..230.---..----.---.---------.-------.240.--------......250.....-..260.......270.--......280--.......290.......300.......310.....-..--320--........330.......340.......350.......360.......370.......380.......390.......400...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSF
S
R
K
Q
F
A
L
S
A
I
F
V
A
I
L
ATG
G
S
F
M
L
L
HENADAKAAPTAAQ
Q
A
A
TV
D
V
A
P
V
V
S
K
T
I
T
D
W
Q
E
YS
G
R
L
E
A
I
--
D
QVDIRPQVSG
K
L
I
A
V
H
FKDG
S
L
V
KKG
D
L
L
F
T
IDP-------R
P
F
E
A
E
L
N
R
A
K
A
Q
LAS-------A
E
A
Q
V
T
Y
T
A
S
N
L
S
R
I
Q
R
L
I
Q
SNAV
S
R
Q
E
LDLAENDAR-------SAN-------A
N
L
Q
A
A
R
A
A
V
Q
S
A
R
L
N
L
---------
E
Y
T
R
I
TAPVSGR
I
S
R
A
E
V
T
V
G
N
V
VSA-G
N
G
A
Q
V
--
L
T
S
L
V
S
V
S
R
L
Y
A
SF-DV-----
D
E
-
Q
T
Y
L
K
Y
---
I
S----N---Q---------R-------NSSQV--------
P
V
Y
M
GLANETGFTR-EGTINSIDNNLNTTS
G
--
T
I
R
V
R
A
T
FD--NPN
G
V
L
LPG
L
Y
A
R
I
R
LGGGQPR
P
A
I
L
ISPTAVGVD-QD--
K
R
---
F
V
V
V
V
DAKNQ
T
A
Y
R
E
V
KLGAQQD
G
L
Q
I
V
N
S
G
LQAGD
R
I
V
V
N
G
L
Q
RIRPGDPVTP
H
L
VPMPNSQITANATPQPQPTDKTSTPAKG
51
HHSearch
81.88
33%
-12
- C4 -
-
2V4D
-
MEXA_PSEAE
G:
[13-339]
-------------------------------------------
P
E
V
G
I
V
T
L
E
A
Q
T
V
T
L
N
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
--------------
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
A
D
A
N
A
A
Y
L
-------
Q
S
--------------
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
---
Q
A
NA
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
-
T
Q
-----
P
S
-
T
A
L
L
R
L
---
R
R
ELAS
G
---
Q
LERAGDNAA
K
---------------------
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
G
V
K
Q
K
A
I
L
A
P
Q
Q
G
V
T
R
D
L
K
G
--
Q
A
---
T
A
L
V
V
N
A
Q
N
K
V
E
L
R
V
I
K
A
D
R
V
I
G
D
K
W
L
V
T
E
G
L
N
A
G
D
K
I
I
T
E
G
L
Q
F
V
Q
P
G
V
E
V
K
T
V
P
----------------------------
1
PsiBlast_PDB
81.69
33%
-14
- C4 -
-
5V5S
-
ACRA_ECOLI
D:
[38-377]
-------------------------------------------
P
A
V
G
V
V
T
V
K
T
E
P
L
Q
I
T
T
E
L
P
G
R
T
S
A
Y
--
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
-------
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
-------
A
Q
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
-------
Q
A
N
-------
A
A
V
T
A
A
K
A
A
V
E
T
A
R
I
N
L
---------
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
N
-
G
Q
-
A
T
A
--
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
-
T
Q
-----
S
S
-
N
D
F
L
R
L
KQE
L
A
----
N
GTL
K
---------
Q
-------
E
N
G
K
A
--------
K
V
S
L
I
T
S
D
G
I
K
F
P
Q
-
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
G
--
C
I
T
L
R
A
I
F
P
--
N
P
D
H
T
L
L
P
G
M
F
V
R
A
R
L
E
E
G
L
N
P
N
A
I
L
V
P
Q
Q
--
G
V
T
-
R
T
--
P
R
GDA
T
V
L
V
V
G
A
D
D
K
V
E
T
R
P
I
V
A
S
Q
A
I
G
D
K
W
L
V
T
E
G
L
K
A
G
D
R
V
V
I
S
G
L
Q
K
V
R
P
G
V
Q
V
K
A
Q
E
----------------------------
2
PsiBlast_PDB
78.77
34%
-7
- C4 -
-
5NG5
-
ACRA_ECOLI
E:
[14-353]
-------------------------------------------
P
A
V
G
V
V
T
V
K
T
E
P
L
Q
I
T
T
E
L
P
G
R
T
S
A
Y
--
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
-------
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
-------
A
Q
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
-------
Q
A
N
-------
A
A
V
T
A
A
K
A
A
V
E
T
A
R
I
N
L
---------
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
N
-
G
Q
A
------
T
A
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
TQSSN
D
M
-
M
R
L
K
Q
E
---
L
A
----
N
GTL
K
---------
Q
-------
E
N
G
K
A
--------
K
V
S
L
I
T
S
D
G
I
K
F
P
Q
-
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
G
--
S
I
T
L
R
A
I
F
P
--
N
P
D
H
T
M
M
P
G
M
F
V
R
A
R
L
E
E
G
L
N
P
N
A
I
L
V
P
Q
Q
--
G
V
T
-
R
T
--
P
R
GDA
T
V
L
V
V
G
A
D
D
K
V
E
T
R
P
I
V
A
S
Q
A
I
G
D
K
W
L
V
T
E
G
L
K
A
G
D
R
V
V
I
S
G
L
Q
K
V
R
P
G
V
Q
V
K
A
Q
E
----------------------------
3
PsiBlast_PDB
78.28
34%
-6
- C4 -
-
5O66
-
?
D:
[14-353]
-------------------------------------------
P
A
V
G
V
V
T
V
K
T
E
P
L
Q
I
T
T
E
L
P
G
R
T
S
A
Y
--
R
I
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
-------
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
-------
A
Q
A
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
G
T
Q
Y
I
S
K
Q
E
Y
D
Q
A
L
A
D
A
Q
-------
Q
A
N
-------
A
A
V
T
A
A
K
A
A
V
E
T
A
R
I
N
L
---------
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
N
-
G
Q
A
------
T
A
L
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
TQSSN
D
M
-
M
R
L
K
Q
E
---
L
A
----
N
GTL
K
---------
Q
-------
E
N
G
K
A
--------
K
V
S
L
I
T
S
D
G
I
K
F
P
Q
-
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
G
--
S
I
T
L
R
A
I
F
P
--
N
P
D
H
T
M
M
P
G
M
F
V
R
A
R
L
E
E
G
L
N
P
N
A
I
L
V
P
Q
Q
--
G
V
T
-
R
T
--
P
R
GDA
T
V
L
V
V
G
A
D
D
K
V
E
T
R
P
I
V
A
S
Q
A
I
G
D
K
W
L
V
T
E
G
L
K
A
G
D
R
V
V
I
S
G
L
Q
K
V
R
P
G
V
Q
V
K
A
Q
E
----------------------------
53
HHSearch
73.87
28%
6
- C4 -
-
5NIK
-
?
G:
[34-366]
-------------------------------------------
P
T
Y
Q
T
L
I
V
R
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
--
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
-------
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
LRAQRQQ
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
-------
V
K
Q
AQIGTID
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
---------
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
-
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
-
Q
V
-----
S
E
-
A
D
V
I
H
L
---
K
P
----
G
---
Q
---------
K
---------------------
A
W
F
T
V
L
G
D
Q
L
T
R
Y
-
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
AI
F
Y
Y
A
R
F
E
V
P
--
N
P
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
I
P
L
S
A
L
G
D
P
-
V
G
DN
R
Y
---
K
V
K
L
L
R
-
N
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
G
E
A
K
----------------------------------------
10
PsiBlast_PDB
71.36
29%
9
- C4 -
-
5NIL
-
?
D:
[53-362]
--------------------------------------------------------------
T
G
K
L
D
A
L
--
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
EQAENQI
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
Q
Q
-------
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
VKQAQIG
T
I
D
-------
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
---------
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
-
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
-
Q
V
-----
S
E
-
A
D
V
I
H
L
---
K
P
----
G
---
Q
---------
K
--------------------
A
W
F
T
V
L
G
D
Q
--
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
--
A
I
F
Y
Y
A
R
F
E
VP
N
P
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
I
P
L
S
A
L
G
D
P
V
G
D
--
N
R
---
Y
K
V
K
L
L
R
N
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
--------------------------------------------
9
PsiBlast_PDB
71.36
29%
9
- C4 -
-
5NIK
-
?
D:
[53-362]
--------------------------------------------------------------
T
G
K
L
D
A
L
--
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
EQAENQI
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
Q
Q
-------
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
Q
D
L
D
N
A
A
T
E
M
A
VKQAQIG
T
I
D
-------
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
---------
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
A
-
A
Q
Q
A
P
N
--
I
L
T
L
A
D
M
S
A
M
L
V
K
A
-
Q
V
-----
S
E
-
A
D
V
I
H
L
---
K
P
----
G
---
Q
---------
K
--------------------
A
W
F
T
V
L
G
D
Q
--
L
T
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
--
A
I
F
Y
Y
A
R
F
E
VP
N
P
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
I
P
L
S
A
L
G
D
P
V
G
D
--
N
R
---
Y
K
V
K
L
L
R
N
G
E
T
R
E
R
E
V
T
I
G
A
R
N
D
T
D
V
E
I
V
K
G
L
E
A
G
D
E
V
V
I
--------------------------------------------
70
Fugue
67.14
33%
-39
* C4 *
-
1T5E
1
MEXA_PSEAE
A:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
-------
A
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
-------
K
Q
Q
Y
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
V
D
V
-
T
Q
-----
P
S
-
T
A
L
L
R
L
---
R
R
----
E
---
L
---------
A
S
GQLERA
G
D
N
A
A
--------
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
52
HHSearch
66.93
25%
13
- C4 -
-
3LNN
-
?
A:
[22-350]
-------------------------------------
A
E
S
P
L
R
R
T
L
A
V
A
P
A
T
R
E
T
V
A
A
P
F
N
L
P
A
M
I
E
A
D
PA
K
L
V
K
V
L
P
P
L
A
G
R
I
V
S
L
N
K
Q
L
G
D
E
V
K
A
G
D
V
L
F
T
I
D
S
-------
A
D
L
A
----
Q
A
N
S
D
A
A
K
-------
A
R
A
A
M
T
M
A
R
R
N
L
D
R
Q
R
E
L
D
K
S
E
I
A
A
K
R
D
F
E
Q
A
Q
S
D
Y
D
-------
Q
A
A
-------
S
E
S
Q
R
A
D
A
R
L
A
Q
L
G
A
K
G
GGTLQAGGG
H
I
L
A
V
R
S
P
I
N
G
R
V
V
D
L
N
A
A
T
G
A
Y
W
N
D
T
T
---
A
S
--
L
M
T
V
A
D
L
S
H
V
F
V
T
A
-
N
A
-----
Q
E
-
K
D
L
G
H
V
---
Y
V
----
G
---
Q
---------
S
---------------------
A
T
V
K
F
D
A
Y
D
-
D
P
Q
-
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
T
R
--
T
T
K
V
R
M
V
F
D
--
N
P
D
G
R
L
R
P
G
M
F
A
Q
A
T
F
L
S
Q
P
-
H
E
G
I
V
V
P
M
S
A
I
V
Q
S
-
G
F
--
Y
T
---
R
A
F
V
E
V
A
P
W
Q
F
E
P
R
V
I
K
L
G
A
Q
I
G
D
R
M
E
V
K
S
G
L
S
A
G
D
R
V
V
V
K
E
G
V
L
L
N
D
------------------------------------
41
PsiBlast_CBE
66.48
31%
-37
- C4 -
-
1T5E
1
MEXA_PSEAE
E:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
66.26
31%
-45
- C4 -
-
2V4D
-
MEXA_PSEAE
A:
[28-259]
----------------------------------------------------------
N
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDN
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
66.22
31%
-43
- C4 -
-
1T5E
1
MEXA_PSEAE
M:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
66.19
31%
-38
- C4 -
-
1T5E
2
MEXA_PSEAE
C:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
66.15
31%
-38
- C4 -
-
1T5E
2
MEXA_PSEAE
K:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
66.00
31%
-38
- C4 -
-
1T5E
2
MEXA_PSEAE
J:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.85
31%
-42
- C4 -
-
1T5E
1
MEXA_PSEAE
A:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDN
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
65.77
31%
-39
- C4 -
-
1T5E
2
MEXA_PSEAE
G:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
65.76
31%
-42
- C4 -
-
1T5E
2
MEXA_PSEAE
D:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
65.46
31%
-37
- C4 -
-
1T5E
2
MEXA_PSEAE
F:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
65.42
31%
-39
- C4 -
-
1T5E
2
MEXA_PSEAE
L:
[29-259]
-----------------------------------------------------------
T
E
L
P
G
R
T
N
A
F
--
R
I
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
-------
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
-------
T
Q
E
Q
A
-------
Q
R
Y
K
L
L
V
A
D
Q
A
V
S
K
Q
Q
Y
-------
A
-------
D
A
N
-------
A
A
Y
L
Q
S
K
A
A
V
E
Q
A
R
I
N
L
---------
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
N
-
G
Q
-
A
N
A
--
M
A
T
V
Q
Q
L
D
P
I
Y
--
V
-
D
V
-----
T
Q
P
S
T
A
L
L
R
---
L
R
----
R
---
E
---------
L
-------
A
S
G
Q
L
ERAGDNAA
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
-
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
--
S
V
T
I
R
A
V
F
P
--
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
-----------------------------------------------------------------------------------------------------------------