@TOME V2.3
(Mar 2018)
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-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLG5: (2017-11-02 )
MKLKMRLKHIILTTCLCSTLAMAELPQDSRRPGGIAVIPLTSDITQVTFQHKPVLISQEGQQRYAVFGIPLSTPLGSVQLETNKAPIQIEVKSYPYAEQRLKVTNQDYVNPNQSQLDRYAQEAKEQNDVYSSFTQSSWQALPKFIRPTSGKFTNSFGRKRFFNGEERAPHSGLDIPAPIGQKVVAPADGVVVQTGHYFFNGQTVLIDHGQGLISMFCHLSEIRVEKGQHIRQGETLGLVGKTGRVTGPHLHWGMSLNNARVDPQLFLTTTH
Atome Classification :
(20 SA)
....----.....10........20........30....-------....40..--..--....---50--......-..-.60.......-.70......--..80--....----....90..---......100.......110.......120.......130...--------...-.140....-...-150........160---------------.-........170...------....180.......190-.....-------...200-........210.......220.--......230......--------.240.......250....----..--------.260..-.....270-----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MK
L
K
----
M
R
L
K
H
I
I
L
T
T
C
L
C
S
T
L
A
M
A
ELPQDSRRPG
G
I
-------
A
V
I
PLTSD--I
T
--
Q
V
T
F---Q---HK
P
V
L
I-SQ-EGQ
Q
R
Y
A
V
F
G
-
I
PLSTPL
G
S
--
V
Q
L
E--TNKA----
P
I
Q
I
E
VKS---YP
Y
A
E
Q
R
LKVTNQDYVNP
N
Q
S
Q
L
D
R
Y
A
Q
E
A
K
E
Q
N
D
V
Y
S
S
F
T
Q
--------
S
S
W
-
Q
A
L
P
K
F
IR-PTS-G-KF
T
N
S
FGRKR-----------------F-FNGEERAPHSGLDI------PAPIGQKVVAPAD
G
V
V
--
V
QT
G
H
-------
Y
F
FNG--
Q
T
V
L
I
DHGQ
G
L
I
S
M
F
C
H
L
S
E
I
R
--VEKGQHIRQGE
T
L
G
L--------VGKTGRVTGP
H
L
H
W
GMSL----NN--------ARVD
P
Q
-
L
F
L
T
TTH------------------------------------------------
1
PsiBlast_PDB
87.81
47%
1
- C2 -
-
2HSI
-
?
A:
[36-277]
-----------------------------------
P
G
G
V
-------
A
V
V
D
L
G
E
E
G
P
P
P
--
R
A
F
Y
---
Q
---
G
K
P
V
L
V
V
R
E
-
E
G
R
R
W
I
A
V
V
G
-
I
P
L
S
T
K
P
G
P
--
Q
K
L
E
--
V
R
A
A
T
G
N
H
E
E
R
F
S
V
G
S
---
K
------------------
P
E
D
L
K
R
I
E
R
E
L
A
E
Q
T
A
A
Y
R
R
F
S
P
--------
G
L
P
-
S
N
L
-
M
L
D
K
-
P
V
D
-
G
-
P
L
S
S
P
F
------------------------------
P
H
S
G
L
D
F
------
A
V
P
A
G
T
P
I
K
A
P
A
A
G
K
V
--
I
L
I
G
D
-------
Y
F
F
N
G
--
K
T
V
F
V
D
H
G
Q
G
F
I
S
M
F
C
H
L
S
K
I
D
--
V
K
L
G
Q
Q
V
P
R
G
G
V
L
G
K
--------
V
G
A
T
G
R
A
T
G
P
H
M
H
W
N
V
S
L
----
N
D
--------
A
R
V
D
P
A
-
I
F
I
----------------------------------------------------
44
HHSearch
87.28
47%
-5
- C2 -
-
2HSI
-
?
A:
[30-279]
-----------------------------
L
L
N
K
P
V
P
G
G
V
-------
A
V
V
D
L
G
E
E
--
G
P
P
P
R
A
F
Y
---
Q
---
G
K
P
V
L
V
-
V
R
E
E
G
R
R
W
I
A
V
V
G
-
I
P
L
S
T
K
P
G
P
Q
K
L
E
V
R
A
A
T
G
N
H
----
E
E
R
F
S
V
G
S
---
K
------------------
P
E
D
L
K
R
I
E
R
E
L
A
E
Q
T
A
A
Y
R
R
F
S
----------
P
G
L
P
S
N
L
M
L
D
K
-
P
V
D
-
G
-
P
L
S
S
P
F
------------------------------
P
H
S
G
L
D
F
------
A
V
P
A
G
T
P
I
K
A
P
A
A
G
K
V
--
I
L
I
G
D
-------
Y
F
F
N
G
--
K
T
V
F
V
D
H
G
Q
G
F
I
S
M
F
C
H
L
S
K
I
D
--
V
K
L
G
Q
Q
V
P
R
G
G
V
L
G
K
--------
V
G
A
T
G
R
A
T
G
P
H
M
H
W
N
V
S
L
----
N
D
--------
A
R
V
D
P
A
-
I
F
I
G
A
--------------------------------------------------
45
HHSearch
86.54
47%
-6
- C2 -
-
2HSI
-
?
B:
[30-279]
-----------------------------
L
L
N
K
P
V
P
G
G
V
-------
A
V
V
D
L
G
E
E
--
G
P
P
P
R
A
F
Y
---
Q
---
G
K
P
V
L
V
-
V
R
E
E
G
R
R
W
I
A
V
V
G
-
I
P
L
S
T
K
P
G
P
Q
K
L
E
V
R
A
A
T
G
N
H
----
E
E
R
F
S
V
G
S
---
K
-----------------
L
P
E
D
L
K
R
I
E
R
E
L
A
E
Q
T
A
A
Y
R
R
F
S
----------
P
G
L
P
S
N
L
M
L
D
K
-
P
V
D
-
G
-
P
L
S
S
P
F
G
-----------------------------
P
H
S
G
L
D
F
------
A
V
P
A
G
T
P
I
K
A
P
A
A
G
K
V
--
I
L
I
G
D
-------
Y
F
F
N
G
--
K
T
V
F
V
D
H
G
Q
G
F
I
S
M
F
C
H
L
S
K
I
D
--
V
K
L
G
Q
Q
V
P
R
G
G
V
L
G
K
--------
V
G
A
T
G
R
A
T
G
P
H
M
H
W
N
V
S
L
----
N
D
--------
A
R
V
D
P
A
-
I
F
I
G
A
--------------------------------------------------
34
Fugue
76.48
38%
25
- C2 -
-
2HSI
-
?
A:
[25-281]
------------------------
S
F
I
M
R
L
L
N
K
P
V
P
G
G
V
-------
A
V
V
D
L
G
E
E
--
G
P
--
P
P
R
A
---
F
Y
QG
K
P
V
L
V
V
-
R
E
-
E
G
R
R
W
I
A
V
V
G
-
I
P
L
S
T
K
P
G
P
--
Q
K
L
E
--
V
R
A
A
----
T
--------------
G
N
H
E
E
R
F
S
V
G
S
K
P
E
D
L
K
R
I
E
R
E
L
A
E
Q
T
A
A
Y
R
R
F
S
P
------------
G
L
-
P
S
N
L
M
L
D
K
-
P
V
D
-
G
-
P
L
S
S
P
F
------------------------------
P
H
S
G
L
D
F
------
A
V
P
A
G
T
P
I
K
A
P
A
A
G
K
V
--
I
L
I
G
D
-------
Y
F
F
N
G
--
K
T
V
F
V
D
H
G
Q
G
F
I
S
M
F
C
H
L
S
K
I
D
--
V
K
L
G
Q
Q
V
P
R
G
G
V
L
G
K
--------
V
G
A
T
G
R
A
T
G
P
H
M
H
W
N
V
S
L
----
N
D
--------
A
R
V
D
P
A
-
I
F
I
G
A
F
Q
------------------------------------------------
4
PsiBlast_PDB
61.51
35%
29
- C2 -
-
5KVP
1
?
A:
[28-146]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
G
Y
P
G
--
H
V
G
V
D
Y
------
A
V
P
V
G
T
P
V
R
A
V
A
N
G
T
V
--
K
F
A
G
N
GANHPWM
L
W
M
A
G
--
N
A
V
L
I
Q
H
A
D
G
M
H
T
G
Y
A
H
L
S
K
I
S
--
V
S
T
D
S
T
V
K
Q
G
Q
I
I
G
Y
--------
T
G
A
T
G
Q
V
T
G
P
H
L
H
F
E
M
L
P
----
A
N
PNWQNGFS
G
R
I
D
P
T
-
G
Y
I
----------------------------------------------------
19
PsiBlast_PDB
61.22
29%
-105
- C2 -
-
4BH5
-
ENVC_ECOLI
A:
[24-140]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
R
-
G
-
P
T
L
H
R
Y
G
E
Q
--------------------
L
Q
G
E
L
R
--
W
K
G
M
V
I
------
G
A
S
E
G
T
E
V
K
A
I
A
D
G
R
V
--
I
L
A
D
W
-------
L
Q
G
Y
G
--
L
V
V
V
V
E
H
G
K
G
D
M
S
L
Y
G
Y
N
Q
S
A
L
--
V
S
V
G
S
Q
V
R
A
G
Q
P
I
A
L
--------
V
G
S
S
G
G
Q
G
R
P
S
L
Y
F
E
I
R
R
----
Q
G
--------
Q
A
V
N
P
Q
-
P
W
L
----------------------------------------------------
57
HHSearch
58.26
26%
-102
- C2 -
-
4BH5
1
ENVC_ECOLI
C:
[16-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
R
G
Q
A
F
W
-
P
V
R
-
G
-
P
T
L
H
R
Y
G
E
Q
L
-----------------
Q
-
G
----
E
L
R
W
K
G
M
V
I
------
G
A
S
E
G
T
E
V
K
A
I
A
D
G
R
V
--
I
L
A
D
W
-------
L
Q
G
Y
G
--
L
V
V
V
V
E
H
G
K
G
D
M
S
L
Y
G
Y
N
Q
S
A
L
--
V
S
V
G
S
Q
V
R
A
G
Q
P
I
A
L
--------
V
G
S
S
G
G
Q
G
R
P
S
L
Y
F
E
I
R
R
----
Q
G
--------
Q
A
V
N
P
Q
-
P
W
L
G
---------------------------------------------------
2
PsiBlast_PDB
58.17
38%
-101
- C2 -
-
2GU1
-
?
A:
[231-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
H
N
G
T
D
F
------
A
T
P
I
G
A
P
V
Y
S
T
G
D
G
K
V
--
I
V
V
R
K
-------
H
P
Y
A
G
--
N
Y
L
V
I
E
H
N
S
V
Y
K
T
R
Y
L
H
L
D
K
I
L
--
V
K
K
G
Q
L
V
K
R
G
Q
K
I
A
L
--------
A
G
A
T
G
R
L
T
G
P
H
L
H
F
E
V
L
V
----
R
N
--------
R
P
V
D
----------------------------------------------------------
5
PsiBlast_PDB
58.01
33%
-24
- C2 -
-
5J1L
-
?
B:
[43-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
V
E
S
G
I
D
F
------
I
A
P
L
N
T
P
V
Y
A
S
A
D
G
I
V
D
F
V
K
T
N
S
-------
N
V
G
Y
G
--
N
L
V
R
I
E
H
A
F
G
F
S
S
I
Y
T
H
L
D
H
V
N
--
V
Q
P
K
S
F
I
Q
K
G
Q
L
I
G
Y
--------
S
G
K
S
G
N
S
G
G
E
K
L
H
Y
E
V
R
F
----
L
G
--------
K
I
L
D
A
Q
-
K
F
L
A
---------------------------------------------------
6
PsiBlast_PDB
57.81
33%
-23
- C2 -
-
5J1M
-
?
B:
[43-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
V
E
S
G
I
D
F
------
I
A
P
L
N
T
P
V
Y
A
S
A
D
G
I
V
D
F
V
K
T
N
S
-------
N
V
G
Y
G
--
N
L
V
R
I
E
H
A
F
G
F
S
S
I
Y
T
H
L
D
H
V
N
--
V
Q
P
K
S
F
I
Q
K
G
Q
L
I
G
Y
--------
S
G
K
S
G
N
S
G
G
E
K
L
H
Y
E
V
R
F
----
L
G
--------
K
I
L
D
A
Q
-
K
F
L
A
---------------------------------------------------
3
PsiBlast_PDB
57.48
42%
-79
- C2 -
-
3SLU
-
?
A:
[246-338]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
T
G
I
D
Y
------
A
A
P
Q
G
T
P
V
R
A
S
A
D
G
V
I
--
T
F
K
G
R
-------
K
G
G
Y
G
--
N
A
V
M
I
R
H
A
N
G
V
E
T
L
Y
A
H
L
S
A
F
S
--
Q
A
Q
G
-
N
V
R
G
G
E
V
I
G
F
--------
V
G
S
T
G
R
S
T
G
P
H
L
H
Y
E
A
R
I
----
N
G
--------
Q
P
V
N
P
---------------------------------------------------------
32
PsiBlast_CBE
57.10
31%
-38
- C2 -
-
4QP5
1
B:
[33-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
G
V
D
F
------
F
M
N
I
G
T
P
V
K
A
I
S
S
G
K
I
--
V
E
A
G
W
-------
S
N
Y
G
G
GN
Q
I
G
L
I
E
N
D
G
V
H
R
Q
W
Y
M
H
L
S
K
Y
N
--
V
K
V
G
D
Y
V
K
A
G
Q
I
I
G
W
--------
S
G
S
T
G
Y
S
T
A
P
H
L
H
F
Q
R
M
V
NSFS
N
S
--------
T
A
Q
D
P
M
-
P
F
L
K
S
--------------------------------------------------
39
Fugue
56.84
22%
19
- C2 -
-
4RNZ
3
?
A:
[1-369]
M
E
R
L
V
W
D
K
L
T
L
L
G
F
L
E
K
N
H
I
P
Q
K
L
Y
Y
N
L
S
S
Q
D
K
E
L
S
A
E
I
QSN
V
T
Y
Y
T
L
R
D
A
N
N
T
--
L
I
--
Q
A
L
I
P
IS
Q
---
D
L
Q
I
H
I
-
Y
K
-
K
G
E
D
Y
F
L
D
F
I
P
I
I
F
T
R
K
E
K
T
--
L
L
L
S
--
L
Q
T
S
----
P
Y
Q
D
I
I
K
A
TND
P
L
L
A
N
Q
L
M
N
A
Y
K
K
S
V
P
F
K
R
L
V
K
N
D
K
I
A
I
V
Y
T
R
D
Y
R
V
G
Q
A
F
G
Q
P
T
I
K
M
A
M
V
S
S
R
-
S
N
Q
Y
Y
L
F
S
-
H
S
N
-
G
-
H
Y
Y
D
S
K
A
Q
E
V
AGFLLETPVKYTRISSP
F
-
S
Y
G
R
F
H
R
P
H
Y
G
V
D
Y
------
A
A
K
H
G
S
L
I
H
S
A
S
D
G
R
V
--
G
F
M
G
V
-------
K
A
G
Y
G
--
K
V
V
E
I
H
L
N
E
-
L
R
L
V
Y
A
H
M
S
A
F
A
NG
L
K
K
G
S
F
V
K
K
G
Q
I
I
G
R
--------
V
G
S
T
G
----
P
H
L
H
F
G
V
Y
K
----
N
S
--------
R
P
I
N
P
L
-
G
Y
I
R
T
A
K
S
K
L
H
G
K
Q
R
E
V
F
L
E
K
A
Q
R
S
K
Q
K
L
E
E
L
L
K
T
H
SFEKNSFYLLEGFLEHHHH
12
PsiBlast_PDB
56.73
31%
-36
- C2 -
-
4QP5
1
LSTP_STASI
A:
[33-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
G
V
D
F
------
F
M
N
I
G
T
P
V
K
A
I
S
S
G
K
I
--
V
E
A
G
W
-------
S
N
Y
G
G
GN
Q
I
G
L
I
E
N
D
G
V
H
R
Q
W
Y
M
H
L
S
K
Y
N
--
V
K
V
G
D
Y
V
K
A
G
Q
I
I
G
W
--------
S
G
S
T
G
Y
S
T
A
P
H
L
H
F
Q
R
M
V
NSFS
N
S
--------
T
A
Q
D
P
M
-
P
F
L
K
S
--------------------------------------------------
52
HHSearch
56.47
34%
-16
- C2 -
-
3SLU
-
?
A:
[217-343]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
N
I
E
P
L
V
Y
T
-
R
I
S
S
P
F
G
Y
R
M
-----------------
H
-
P
I
L
H
T
W
R
L
H
T
G
I
D
Y
------
A
A
P
Q
G
T
P
V
R
A
S
A
D
G
V
I
--
T
F
K
G
R
-------
K
G
G
Y
G
--
N
A
V
M
I
R
H
A
N
G
V
E
T
L
Y
A
H
L
S
A
F
S
--
Q
A
-
Q
G
N
V
R
G
G
E
V
I
G
F
--------
V
G
S
T
G
R
S
T
G
P
H
L
H
Y
E
A
R
I
----
N
G
--------
Q
P
V
N
P
V
-
S
V
A
L
---------------------------------------------------
11
PsiBlast_PDB
56.37
31%
-37
- C2 -
-
4QPB
-
LSTP_STASI
A:
[33-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
G
V
D
F
------
F
M
N
I
G
T
P
V
K
A
I
S
S
G
K
I
--
V
E
A
G
W
-------
S
N
Y
G
G
GN
Q
I
G
L
I
E
N
D
G
V
H
R
Q
W
Y
M
H
L
S
K
Y
N
--
V
K
V
G
D
Y
V
K
A
G
Q
I
I
G
W
--------
S
G
S
T
G
Y
S
T
A
P
H
L
H
F
Q
R
M
V
NSFS
N
S
--------
T
A
Q
D
P
M
-
P
F
L
K
S
--------------------------------------------------
48
HHSearch
56.28
32%
-15
- C2 -
-
4RNZ
-
?
A:
[187-319]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
F
L
L
E
T
-
P
V
K
-
Y
T
R
I
S
S
P
F
S
Y
G
R
-----------------
F
H------
R
P
H
Y
G
V
D
Y
------
A
A
K
H
G
S
L
I
H
S
A
S
D
G
R
V
--
G
F
M
G
V
-------
K
A
G
Y
G
--
K
V
V
E
I
-
H
L
N
E
L
R
L
V
Y
A
H
M
S
A
F
A
NG
L
K
K
G
S
F
V
K
K
G
Q
I
I
G
R
--------
V
G
----
S
T
G
P
H
L
H
F
G
V
Y
K
----
N
S
--------
R
P
I
N
P
L
-
G
Y
I
R
T
--------------------------------------------------
53
HHSearch
56.17
34%
-22
- C2 -
-
3SLU
-
?
B:
[217-343]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
N
I
E
P
L
V
Y
T
-
R
I
S
S
P
F
G
Y
R
M
-----------------
H
-
P
I
L
H
T
W
R
L
H
T
G
I
D
Y
------
A
A
P
Q
G
T
P
V
R
A
S
A
D
G
V
I
--
T
F
K
G
R
-------
K
G
G
Y
G
--
N
A
V
M
I
R
H
A
N
G
V
E
T
L
Y
A
H
L
S
A
F
S
--
Q
A
-
Q
G
N
V
R
G
G
E
V
I
G
F
--------
V
G
S
T
G
R
S
T
G
P
H
L
H
Y
E
A
R
I
----
N
G
--------
Q
P
V
N
P
V
-
S
V
A
L
---------------------------------------------------
31
PsiBlast_CBE
56.04
31%
-38
- C2 -
-
4QPB
1
B:
[33-138]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
G
V
D
F
------
F
M
N
I
G
T
P
V
K
A
I
S
S
G
K
I
--
V
E
A
G
W
-------
S
N
Y
G
G
GN
Q
I
G
L
I
E
N
D
G
V
H
R
Q
W
Y
M
H
L
S
K
Y
N
--
V
K
V
G
D
Y
V
K
A
G
Q
I
I
G
W
--------
S
G
S
T
G
Y
S
T
A
P
H
L
H
F
Q
R
M
V
NSFS
N
S
--------
T
A
Q
D
P
M
-
P
F
L
K
S
--------------------------------------------------
40
Fugue
55.84
26%
5
- C2 -
-
3IT5
-
LASA_PSEAE
A:
[1-182]
----------------------------------------------------------------------------------------------------------------------------
A
---
P
P
S
N
L
M
Q
L
P
W
R
Q
G
Y
S
W
Q
P
N
G
A
H
-----------------------------------------
S
N
T
-
G
-
S
---------------------------------
G
Y
P
Y
S
S
F
D
A
S
YDWPR
W
G
S
A
T
Y
S
V
V
A
A
H
A
G
T
V
--
R
V
L
S
------------
R
--
C
Q
V
R
V
T
H
P
S
G
W
A
T
N
Y
Y
H
M
D
Q
I
Q
--
V
S
N
G
Q
Q
V
S
A
D
T
K
L
G
V
YAGN
I
N
T
A
L
C
E
G
G
S
S
T
G
P
H
L
H
F
S
L
L
Y
----
N
G
--------
A
F
V
S
L
Q
G
A
S
F
G
P
Y
R
I
N
V
G
TSNYDNDCRR
Y
Y
F
Y
NQSAG
T
T
H
C
A
F
R
P
L
Y
N
PGLAL---------