@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLJ8: (2017-11-03 )
MLTYGQTKRLRQSKIHASEVITLLLWFHLTGSRNFKAFYLYWAKPFLCSYFTNLPSYSRFIELKAKYAMYFVALIESLKVHSAGIAFIDSTKLAVCHNKRIHQHRVFADSASRGKTSVDWFYGFKIHLICDHIGRLVSYCITTGNVDDRKVLPDLIEHSKLKGKLFGDRGYVGKNWKSRLAEVGVQLITRVKRNMKPQVLAPFDHAVLKKRGIIEAPFKLMKCQFDLEHGRHRSKMGLLTTIFAALTLYALVLVNGYKSGIQQILKPIDLNSA
Atome Classification :
(17 SA)
----------.........10....--....20........30.------........40......-------------..50.....--------------...60-----........70........80......-..90......---..100.......110...--------....120...---------....130.-.----------------.....140.....-----..150......-.160.......--170........180.......190-----------------........200.-------......210.......220..---.....230......--.240..---....--.250......-.260.....------..270.------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------MLTYG
Q
T
K
R
L
R
Q
SKI--
H
A
S
E
V
I
T
L
L
L
W
F
HLT-G------SR
N
F
K
A
F
Y
L
Y
WA
K
P
F
L
-------------
C
S
Y
F
TNLP
S
--------------
Y
S
R
F
I
-----
E
L
K
A
K
Y
A
M
Y
F
V
A
L
I
E
S
L
KVHSA
G
I
A
F
-IDS
T
K
L
A
V
C
H---NKRI
H
Q
H
R
VFADSASRGK--------
T
S
V
D
W
F
Y
G
F
K
---------
I
H
L
I
C
D
H
I
-
G
----------------
R
L
V
S
Y
C
ITTGNVD-----
D
R
K
V
L
P
D
L
I
E
H
-
S
KLK
G
K
L
FGDR--GY-VG
K
N
W
K
S
R
L
A
E
V
G
V
Q
L
I
T
R
V
------------------
K
RNMKP
Q
V
LAPF-------
D
H
A
V
L
K
KRGIIEA
P
F
K
L
M
K
C
Q
---
F
D
L
E
HGR
H
R
S
KM
G
L
--
L
T
T
I
F
A
---
A
L
T
L
--
Y
A
L
V
L
V
N
G
Y
K
-
S
G
I
Q
Q
I
L
K
P------IDLNSA------------
20
Fugue
59.75
17%
-4
- C3 -
-
5MG8
2
SMC6_SCHPO
B:
[23-286]
------------
S
Q
I
E
K
R
A
N
E
S
N
N
L
--
Q
R
E
I
A
D
L
S
E
Q
I
V
E
L
E
-
S
------
K
R
N
D
L
H
S
A
L
L
E
M
G
G
N
L
-------------
T
S
L
L
T
K
K
D
S
--------------
I
A
N
K
I
-----
S
D
Q
S
E
H
L
K
V
L
E
D
-
V
Q
R
D
K
V
S
A
F
G
K
N
M
-
P
Q
L
L
K
L
I
T
R
E
---
T
R
F
Q
H
P
P
K
G
P
M
G
K
Y
M
T
V
K
--------
E
-------
Q
K
---------
W
H
L
I
I
E
R
I
L
G
----------------
N
V
I
N
G
F
I
V
R
-
S
H
H
-----
D
Q
L
I
L
K
E
L
M
R
Q
-
S
N
C
H
A
T
V
V
V
G
K
---
Y
-
D
P
F
D
Y
S
S
G
E
P
D
S
Q
Y
P
T
V
L
K
I
---------------------------
I
K
F
-------
D
D
D
E
V
L
H
T
L
I
N
H
L
G
I
E
K
M
L
L
I
---
E
D
R
R
E
A
E
A
Y
M
K
R
G
I
AN
V
T
Q
C
Y
A
L
D
P
R
N
R
G
--
Y
G
F
R
I
V
S
T
Q
R
-
S
S
G
I
S
K
V
T
P
WNRPPR
I
G
F
S
S
S
------------
17
Fugue
57.84
17%
8
* C4 *
-
5JP6
-
?
A:
[23-379]
----------
M
S
Q
I
G
S
S
V
R
Q
A
V
S
D
N
--
Q
S
A
Q
--
T
L
V
E
W
E
N
S
E
-
A
--------
N
P
E
A
L
F
A
N
W
R
H
E
F
M
V
D
SSK
R
E
S
M
K
T
E
L
C
K
E
L
Q
A
L
P
A
QDLTLF
E
N
E
I
R
DEN
N
R
A
L
V
SGC
K
E
E
L
L
A
Q
V
D
E
H
F
D
E
Q
R
E
S
M
S
V
P
G
H
A
L
K
A
-
V
Q
S
R
N
S
F
R
F
P
---
D
N
T
Q
K
R
D
M
S
N
G
Y
M
A
V
R
G
D
VARK
E
V
V
L
T
F
D
D
G
P
H
G
L
Y
---------
T
D
A
I
L
R
A
L
-
K
----------------
E
V
N
A
K
A
M
F
F
A
T
G
K
-----
S
V
R
T
N
P
E
A
L
K
R
-
V
A
A
D
G
H
V
I
G
S
H
--
S
I
T
L
T
F
D
E
A
A
A
E
V
R
G
G
H
Q
A
V
F
D
V
LG
W
V
D
P
V
F
R
FYGETS
K
D
L
K
A
F
L
K
T
K
S
T
G
E
F
A
W
NIESD
D
W
R
T
Q
S
N
E
Q
L
L
A
R
V
L
A
N
V
E
S
Q
GR
G
I
V
L
F
H
D
I
Q
R
R
T
A
E
I
--
M
P
Q
F
L
R
---
E
L
Y
N
R
G
Y
S
V
V
L
L
T
A
A
D
-
P
S
A
K
Y
N
S
K
L
------
V
K
R
K
--------------
19
Fugue
57.76
12%
-111
- C4 -
-
4BYZ
-
?
A:
[1-194]
---------------
Y
T
M
S
A
Q
V
I
Q
I
--
G
R
Q
R
F
V
G
G
L
F
W
Q
S
L
S
-
R
------
R
N
E
L
R
A
E
A
V
E
L
A
K
K
L
K
-------------
F
D
L
M
V
L
R
I
D
--------------
R
G
---------------
V
A
A
A
G
Y
A
N
T
R
D
G
F
A
P
G
------
H
L
S
L
G
A
M
V
---
S
R
A
I
A
L
E
G
A
F
Y
N
G
R
R
Q
----------
P
A
P
N
W
L
G
A
F
A
---------
L
P
D
------
G
----------------
R
W
A
Y
F
A
V
R
D
H
--------------
A
F
M
P
N
-
G
D
W
V
G
S
------------------
R
E
E
A
L
E
R
L
H
T
D
Y
------------------
A
W
G
G
W
N
V
V
I
G
E
P
-------
E
L
E
R
Q
G
F
Q
N
F
Q
P
K
R
L
D
D
L
L
P
R
---
R
G
G
R
P
R
T
E
R
W
W
A
------------------------------------
L
R
P
------
V
E
R
R
L
S
------------
11
Fugue
55.36
11%
32
- C5 -
-
1N4K
1
ITPR1_MOUSE
A:
[13-379]
-----GG
D
V
V
R
L
F
H
A
E
Q
E
K
F
L
T
C
D
E
--
H
R
K
K
Q
H
V
F
L
R
T
T
G
R
Q
-
S
------
A
T
S
A
T
S
S
K
A
L
W
E
V
E
V
V
-------------
Q
L
F
R
F
K
H
L
A
--------------
T
G
H
Y
L
-----
A
A
E
V
D
M
V
---
Y
S
L
V
S
V
P
E
G
N
D
I
S
S
I
F
-
E
L
D
P
Y
V
R
L
R
H
LCT
N
T
W
V
H
S
T
N
I
P
I
D
K
E
E
E
K
P
--------
V
M
L
K
I
G
T
S
----------------
P
L
K
-
E
----------------
D
K
E
A
F
A
I
V
P
V
S
P
A
-----
E
V
R
D
L
D
F
A
N
D
A
-
S
K
V
L
G
S
I
A
G
K
L
E
K
G
T
-
I
T
Q
N
E
R
R
S
V
T
K
L
L
E
D
L
V
Y
F
V
T
G
GTNSGQD---------
V
L
E
V
V
F
S
K
P
N
R
E
-------
R
Q
K
L
M
R
E
Q
N
I
L
K
Q
I
F
K
L
L
Q
A
P
---
F
--
T
H
A
P
F
R
H
I
C
R
L
--
C
Y
R
V
L
R
---
H
S
Q
Q
--
D
Y
R
K
N
Q
E
Y
I
A
-
K
Q
F
G
F
M
Q
K
Q
------
I
G
Y
D
V
L
A
E
D
T
I
T
A
L
L
H
NN
14
Fugue
54.52
20%
1
- C2 -
-
5B22
2
NECT3_MOUSE
A:
[1-209]
-PS
I
I
V
E
P
H
V
T
A
V
W
G
K
N
V
S
L
K
C
-
L
I
--
E
V
N
E
T
I
T
Q
I
S
W
E
K
I
H
-
G
------
K
S
T
Q
T
V
A
V
H
H
--
P
Q
Y
G
-------------
F
S
V
Q
G
D
Y
Q
G
--------------
R
V
L
F
K
-----
N
Y
S
L
N
D
A
--------
T
I
T
L
H
--
N
I
G
F
-
S
D
S
----------
G
K
Y
I
C
K
A
V
T
F
P
L
G
N
A
Q
S
S
--------
T
T
V
T
V
L
V
E
P
T
---------
V
S
L
I
-------------------------------------------------------
K
G
P
---
D
S
--
L
I
-
D
G
G
N
--------
E
T
V
A
A
V
C
V
------------------
A
A
T
G
K
P
V
A
Q
I
D
W
-------
E
G
D
L
G
E
M
E
S
S
T
T
S
-----------
F
P
N
E
T
A
T
I
V
S
Q
Y
K
L
--
F
P
T
R
F
A
---
R
G
R
R
--
I
T
C
V
V
K
H
P
A
L
-
E
K
D
I
R
Y
S
F
I
------
L
D
I
Q
--------------
13
Fugue
52.78
13%
-11
* C5 *
-
1DAR
1
?
?:
[1-328]
-----------
M
A
V
K
V
E
Y
D
L
K
R
---------
L
R
N
I
G
I
A
A
H
I
D
A
G
------
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
A
A
--------------
V
T
T
C
F
W
K
D
--------------
H
R
I
N
I
-----
I
D
T
P
G
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
-
F
D
S
S
Q
G
V
--------
E
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
--------
P
R
I
A
F
A
N
K
M
D
KTGAD
L
W
L
V
I
R
T
M
Q
E
R
L
-
G
A---------------
R
P
V
V
M
Q
L
P
I
G
R
E
D
-----
T
F
S
G
I
I
D
V
L
----
R
M
K
A
Y
T
Y
G
N
D
-----
L
G
T
D
I
R
E
I
----------
P
I
------------------
P
E
E
Y
L
D
Q
A
R
E
Y
H
-------
E
K
L
V
E
V
A
---
A
D
F
D
E
N
I
M
L
K
Y
---
L
E
G
E
E
P
T
E
E
E
L
V
A
A
--
I
R
K
G
T
I
---
D
L
K
I
--
T
P
V
F
L
G
S
A
L
K
N
K
G
V
Q
L
L
L
D
A
------
V
V
D
Y
L
P
S-----------
15
Fugue
46.84
16%
-24
- C5 -
-
4IIK
3
SIDD_LEGPH
A:
[1-314]
MRSIITQICN
G
V
L
H
G
Q
S
Y
Q
S
G
S
N
D
L
DK
G
N
S
E
I
F
A
S
S
L
F
V
H
L
N
-
E
QGKEIK
D
S
D
D
K
I
V
I
G
Y
T
K
D
G
M
A
-------------
F
Q
I
V
V
D
G
F
Y
--------------
G
C
E
R
Q
-----
A
V
F
S
F
I
D
N
Y
V
L
P
L
I
D
N
F
S
L
D
L
T
R
--
Y
-
P
D
S
K
K
V
T
E
S
L
---
I
H
T
I
Y
S
L
R
S
K
H
A
P
L
A
E
F
T
--------
M
S
L
C
V
T
Y
Q
K
D
---------
E
Q
L
F
C
A
G
F
-
G
I
G
D
T
G
I
A
I
K
R
NE
G
T
I
E
Q
L
V
C
H
T
E
V
D
G
F
K
D
AFDNY
S
S
A
N
I
D
L
V
I
E
R
N
S
V
F
N
T
K
V
M
P
G
D
--
E
L
-
V
G
Y
T
Y
V
P
P
M
L
E
M
T
E
K
E
F
E
V
E
------------------
K
R
I
V
R
H
L
N
L
----------
D
P
G
N
F
D
D
K
D
P
L
F
S
Q
L
L
Q
V
V
K
S
---
K
Q
K
Q
L
V
E
Q
A
K
E
T
G
Q
--
I
Q
R
F
G
D
---
D
F
T
V
--
G
R
L
V
I
P
D
-------
Q
L
L
I
N
Q
------
L
R
I
H
A
L
S-----------
10
HHSearch
41.94
13%
-230
- C1 -
-
1OGC
-
RBSD_BACSU
B:
[21-36]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
K
I
V
I
A
D
A
--
G
L
-
P
V
P
D
G
-------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
36.11
9%
-162
- C5 -
-
4HLB
-
?
A:
[34-88]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
Y
A
D
K
--
G
I
-
R
S
V
D
V
A
A
Y
A
K
G
I
D
I
V
F
V
A
A
D
------------------
R
K
M
T
R
A
E
F
-------------
S
-----
A
I
A
S
R
S
I
R
E
L
K
E
R
---
F
G
F
D
K
----------------------------------------------------------------------
4
HHSearch
27.97
14%
-229
- C6 -
-
4Q11
1
?
B:
[5-47]
------------------------------------------------------------------------------------
L
H
P
T
--------------
R
G
K
L
L
-----
K
R
F
A
Q
I
G
P
Y
I
R
E
Q
-----
Q
C
Q
E
S
Q
F
F
-
F
D
C
L
A
V
C
V
N
K
---
K
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
27.75
13%
-231
- C6 -
-
3RPJ
-
?
B:
[9-50]
-------------------------------------------------------------------------------------
H
P
T
--------------
R
G
K
L
L
-----
K
R
F
A
Q
I
G
P
Y
I
R
E
Q
-----
Q
C
Q
E
S
Q
F
F
-
F
D
C
L
A
V
C
V
N
K
---
K
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
26.28
15%
-243
- C5 -
-
4H13
1
PETL_MASLA
E:
[1-32]
------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
F
G
I
A
V
G
I
I
F
-
A
I
K
S
I
K
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
26.10
15%
-245
- C5 -
-
2E74
1
PETL_MASLA
E:
[1-32]
------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
F
G
I
A
V
G
I
I
F
-
A
I
K
S
I
K
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
22.27
16%
-172
* C6 *
-
2MZ8
-
CRL_SALTY
A:
[3-47]
----------------------------------------------------------------------------------
L
P
S
G
H
P
--------------
K
S
R
L
I
-----
K
K
F
T
A
L
G
P
Y
I
R
E
G
-----
Q
C
E
D
N
R
F
F
-
F
D
C
L
A
V
C
V
N
V
---
K
P
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
14.18
29%
0
- C- -
-
1VF5
-
PETL_MASLA
E:
[1-32]
------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
F
G
I
A
V
G
I
I
F
A
I
K
S
I
K
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
7.81
18%
0
- C- -
-
4DM0
-
TN5P_ECOLX
A:
[317-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
G
---
A
G
A
E
R
Q
R
M
E
K
P
D
N
L
--
E
R
M
V
S
I
---
L
S
F
V
A
-
V
R
L
L
Q
L
--------------------------------------
1
HHSearch
7.60
18%
0
- C- -
-
1MUS
1
TN5P_ECOLX
A:
[317-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
G
---
A
G
A
E
R
Q
R
M
E
K
P
D
N
L
--
E
R
M
V
S
I
---
L
S
F
V
--
A
V
R
L
L
Q
--------------------------------------