@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLK5: (2017-11-03 )
MVGISHNQDFFYMKKLISLFLSVSVVLLAACGKRQSEPQNGKDSAQLQTVVIASTGSDADIWRYIATLPETKAAGLKLEVKNFTDYVAMNTATANKEVDLNAFQSYAYLVAFNASNKDKIAPVATTYLEPMGIYSSKYKKVDEFPQGASIAIPNDAANEARALLLLQSAGLIKLKADFDPAKGTPSDITDNSKKIDIKPIQMATAVRVKDEVDAIFLGNTLAMEGGLNVLKDSIYYEPVDQSTKLNVNILATAESRKDDPVLQKVGQLYHTEAVKKYVEQHFGGTKVDVNQPISYLTQAK
Atome Classification :
(20 SA)
.........10........20........30........40........50.....-.---..60........70........80........90........100.......110....-..-.120.......130...------.----.--..140....-...150.......160.......170..-.....180-........190.......200.---........210-........220.......230......-..240-.....--...250...---.---...260.......270.......280.......290.......300--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MVGISHN
Q
D
F
F
Y
M
K
K
L
I
S
L
F
L
S
V
S
V
V
L
L
A
ACGKRQSEPQNGKDS
A
Q
L
Q
T
V
V
I
A
STG-S---
D
A
D
I
W
R
Y
I
A
TLPETKAA
G
L
K
L
E
VKNF
T
D
Y
V
A
MNTATANK
E
V
D
L
N
A
F
Q
S
Y
A
Y
L
V
A
FNASN-KD-KIA
P
V
A
T
T
Y
LEPMGI
Y
S
------
S
----
K
--
Y
K
K
V
D
EFPQ-GA
S
I
AIPNDAAN
E
A
R
A
L
L
L
L
QSA
G
L
I
K
L
-
K
ADFDPA--KGTPSDITDNS
K
K
I
D
I
K
P
I
--
Q
---
M
A
T
A
V
R
VKDE--V
D
A
I
F
LGNTLAMEG
G
L
N
V
L
-
K
DS
I
Y
YE-PVD-Q-S
T
K
L
N
--
V
N
I
L
A
TAES---R---KD
D
P
V
L
Q
K
V
G
Q
L
Y
H
T
E
A
V
K
K
Y
V
E
Q
HFGG
T
K
V
DVNQ
P
I
S
Y
L
TQAK----
1
PsiBlast_PDB
95.83
41%
0
- C- -
-
4K3F
-
?
A:
[29--4]
------------------------------------------------------------------------------
G
V
D
L
K
I
K
E
F
T
D
Y
V
Q
P
N
V
Q
V
S
E
K
R
L
D
A
N
F
F
Q
H
Q
P
Y
L
D
E
F
N
K
A
K
-
G
T
-
D
L
V
A
V
T
G
V
H
I
E
P
L
G
A
Y
S
------
S
----
K
--
Y
K
K
L
D
E
L
P
S
-
G
A
T
V
V
I
P
N
D
A
T
N
G
G
R
A
L
L
L
L
D
K
A
G
V
I
K
L
-
K
-
D
N
K
S
I
--
T
A
T
P
K
D
I
V
D
N
P
K
N
I
K
I
R
E
L
--
E
---
A
A
T
L
P
R
V
L
T
Q
--
V
D
M
A
L
I
N
T
N
Y
A
L
E
A
K
L
N
P
T
-
K
D
A
L
A
I
E
-
G
S
D
-
S
-
P
Y
-----
V
N
I
L
V
A
R
P
D
---
N
---
K
D
S
D
A
M
Q
K
L
A
K
A
L
H
S
A
E
I
K
Q
F
I
Q
E
K
Y
K
G
A
V
V
-----------------
39
HHSearch
92.79
37%
0
- C- -
-
4K3F
-
?
A:
[2--3]
----------------------------------------------
A
E
S
L
T
V
A
A
T
P
V
P
---
H
A
E
I
L
N
-
V
V
K
-
P
L
L
A
K
E
G
V
D
L
K
I
K
E
F
T
D
Y
V
Q
P
N
V
Q
V
S
E
K
R
L
D
A
N
F
F
Q
H
Q
P
Y
L
D
E
F
N
K
A
K
-
G
T
-
D
L
V
A
V
T
G
V
H
I
E
P
L
G
A
Y
S
------
S
----
K
--
Y
K
K
L
D
E
L
-
P
S
G
A
T
V
V
I
P
N
D
A
T
N
G
G
R
A
L
L
L
L
D
K
A
G
V
I
K
L
-
K
D
N
K
-
S
I
--
T
A
T
P
K
D
I
V
D
N
P
K
N
I
K
I
R
E
L
--
E
---
A
A
T
L
P
R
V
L
T
Q
--
V
D
M
A
L
I
N
T
N
Y
A
L
E
A
-
K
L
N
P
T
K
D
A
L
A
I
E
-
G
S
-----
D
S
P
Y
--
V
N
I
L
V
A
R
P
D
---
N
---
K
D
S
D
A
M
Q
K
L
A
K
A
L
H
S
A
E
I
K
Q
F
I
Q
E
K
Y
K
-
G
A
V
V
P
---------------
3
PsiBlast_PDB
90.04
37%
0
- C- -
-
4Q5T
-
?
A:
[19--2]
---------------------------------------------------------
S
---
D
K
E
R
W
D
K
I
E
E
L
--
L
K
K
E
N
I
K
L
K
F
K
E
F
T
D
Y
S
Q
P
N
K
A
L
K
N
G
E
I
D
I
N
S
F
Q
H
Y
N
F
L
N
N
W
N
K
E
N
-
K
G
-
D
L
V
T
V
A
E
T
Y
I
S
P
I
N
L
F
S
G
T
E
NGK
A
----
K
--
Y
S
S
A
K
E
I
P
N
-
G
G
Q
I
A
I
P
N
D
A
T
N
E
S
R
A
L
Y
V
L
Q
D
A
G
L
I
K
L
-
N
V
S
G
D
E
L
---
A
T
V
K
N
I
K
S
N
P
K
N
L
D
I
K
E
V
--
D
---
A
S
Q
T
A
R
N
L
A
S
--
V
D
A
A
V
V
N
N
S
Y
A
V
P
A
K
I
D
-
F
-
K
T
S
L
Y
K
E
-
K
V
N
-
E
-
G
S
K
Q
W
--
I
N
I
I
A
A
Q
K
N
WKK
S
---
K
K
A
A
A
I
K
K
L
I
K
A
Y
H
T
D
A
V
K
K
V
I
K
K
T
A
K
G
----
V
D
E
P
V
-----------
44
HHSearch
87.02
36%
0
- C- -
-
4Q5T
-
?
A:
[4--2]
--------------------------------------------
N
D
K
N
T
L
T
V
G
V
M
T
-
M
T
D
S
D
K
E
R
W
D
K
I
E
E
--
L
L
K
K
E
N
I
K
L
K
F
K
E
F
T
D
Y
S
Q
P
N
K
A
L
K
N
G
E
I
D
I
N
S
F
Q
H
Y
N
F
L
N
N
W
N
K
E
N
-
K
G
-
D
L
V
T
V
A
E
T
Y
I
S
P
I
N
L
F
S
------
G
T
E
NG
K
AK
Y
S
S
A
K
E
I
-
P
N
G
G
Q
I
A
I
P
N
D
A
T
N
E
S
R
A
L
Y
V
L
Q
D
A
G
L
I
K
L
-
N
V
S
G
-
D
E
--
L
A
T
V
K
N
I
K
S
N
P
K
N
L
D
I
K
E
V
--
D
---
A
S
Q
T
A
R
N
L
A
S
--
V
D
A
A
V
V
N
N
S
Y
A
V
P
A
-
K
I
D
F
-
K
T
S
L
Y
K
E
-
K
V
N
-
E
-
G
S
K
Q
W
--
I
N
I
I
A
A
Q
K
N
---
W
KKS
K
K
A
A
A
I
K
K
L
I
K
A
Y
H
T
D
A
V
K
K
V
I
K
K
T
A
K
-
G
V
D
E
P
V
--------------
7
PsiBlast_PDB
83.79
32%
0
- C- -
-
4GOT
-
A:
[3--1]
-------------------------------------------
S
G
K
K
E
I
V
V
A
A
T
K
T
-
P
---
H
A
E
I
L
K
--
E
A
E
P
L
L
K
E
K
G
Y
T
L
K
V
K
V
L
S
D
Y
K
M
Y
N
K
A
L
A
D
K
E
V
D
A
N
Y
F
Q
H
I
P
Y
L
E
Q
E
M
K
E
N
-
T
D
Y
K
L
V
N
A
G
A
V
H
L
E
P
F
G
I
Y
S
------
K
----
T
--
Y
K
S
L
K
D
L
P
D
-
G
A
T
I
I
L
T
N
N
V
A
E
Q
G
R
M
L
A
M
L
E
N
A
G
L
I
T
L
-
D
S
K
V
E
T
V
--
D
A
T
L
K
D
I
K
K
N
P
K
N
L
E
F
K
K
V
AP
E
---
L
T
A
K
A
Y
E
N
K
E
--
G
D
A
V
F
I
N
V
N
Y
A
I
Q
N
K
L
N
P
K
-
K
D
A
I
E
V
E
-------
S
T
K
N
N
PY
A
N
I
I
A
V
R
K
G
---
E
---
E
D
S
A
K
I
K
A
L
M
E
V
L
H
S
K
K
I
K
D
F
I
E
K
K
Y
D
G
A
V
L
P
V
S
E
-------------
13
PsiBlast_PDB
80.53
29%
0
- C- -
-
4EF1
-
?
A:
[8--1]
--------------------------------------------------
V
G
A
S
P
V
-
P
---
H
A
E
I
L
E
H
V
K
P
L
L
E
K
E
--
G
V
K
L
E
V
T
T
Y
T
D
Y
V
L
P
N
K
A
L
E
S
G
D
I
D
A
N
Y
F
Q
H
V
P
F
F
N
E
A
V
K
E
N
-
D
Y
-
D
F
V
N
A
G
A
I
H
L
E
P
V
G
L
Y
S
------
K
----
K
--
Y
K
S
L
Q
E
I
P
D
-
G
S
T
I
Y
V
S
S
S
V
S
D
W
P
R
V
L
T
I
L
E
D
A
G
L
I
T
L
-
K
E
G
V
D
R
T
--
T
A
T
F
D
D
I
D
K
N
T
K
K
L
K
F
N
H
E
--
S
DPA
I
M
T
T
L
Y
D
N
E
E
--
G
A
A
V
L
I
N
S
N
F
A
V
D
Q
G
L
N
P
K
-
K
D
A
I
A
L
E
-----
K
-
E
S
S
P
Y
--
A
N
I
I
A
V
R
K
E
---
D
---
E
N
N
E
N
V
K
K
L
V
K
V
L
R
S
K
E
V
Q
D
W
I
T
K
K
W
N
G
A
I
V
P
V
N
E
-------------
43
HHSearch
78.86
30%
0
- C- -
-
4OTE
-
?
B:
[3--3]
---------------------------------------------
D
D
K
K
I
V
V
G
A
T
L
V
P
---
G
G
E
L
L
E
E
L
-
K
-
P
L
I
K
E
K
G
Y
T
L
E
V
K
N
F
D
D
Y
I
L
P
N
E
A
L
N
N
G
E
I
D
A
N
L
F
Q
H
E
P
Y
L
K
E
A
V
K
A
K
-
G
Y
-
K
I
M
A
G
K
K
L
Y
V
C
P
A
I
L
Y
S
------
Y
----
K
--
I
K
S
V
D
E
F
-
K
K
G
D
T
I
A
I
S
N
N
P
S
S
C
S
K
N
L
R
Y
L
E
S
I
G
L
L
T
L
-
P
K
G
D
--
G
--
L
V
S
P
K
D
I
I
E
N
P
K
G
I
Q
F
K
E
L
--
D
---
I
A
Q
I
P
S
S
L
P
D
--
V
T
A
A
F
I
D
T
T
Y
A
V
P
A
-
G
L
D
A
K
K
N
G
I
Y
T
A
-
P
I
-----
N
D
E
Y
--
A
N
L
L
A
F
R
T
E
---
D
---
K
D
S
E
K
I
K
V
L
Q
D
V
L
T
S
D
K
A
R
S
L
I
E
E
K
Y
K
-
G
I
V
I
P
---------------
42
HHSearch
78.50
30%
0
- C- -
-
4OTE
-
?
A:
[4--3]
----------------------------------------------
D
K
K
I
V
V
G
A
T
L
V
P
---
G
G
E
L
L
E
E
L
-
K
-
P
L
I
K
E
K
G
Y
T
L
E
V
K
N
F
D
D
Y
I
L
P
N
E
A
L
N
N
G
E
I
D
A
N
L
F
Q
H
E
P
Y
L
K
E
A
V
K
A
K
-
G
Y
-
K
I
M
A
G
K
K
L
Y
V
C
P
A
I
L
Y
S
------
Y
----
K
--
I
K
S
V
D
E
F
-
K
K
G
D
T
I
A
I
S
N
N
P
S
S
C
S
K
N
L
R
Y
L
E
S
I
G
L
L
T
L
-
P
K
G
D
--
G
--
L
V
S
P
K
D
I
I
E
N
P
K
G
I
Q
F
K
E
L
--
D
---
I
A
Q
I
P
S
S
L
P
D
--
V
T
A
A
F
I
D
T
T
Y
A
V
P
A
-
G
L
D
A
K
K
N
G
I
Y
T
A
-
P
I
-----
N
D
E
Y
--
A
N
L
L
A
F
R
T
E
---
D
---
K
D
S
E
K
I
K
V
L
Q
D
V
L
T
S
D
K
A
R
S
L
I
E
E
K
Y
K
-
G
I
V
I
P
---------------
14
PsiBlast_PDB
77.52
33%
0
- C- -
-
4OTE
-
?
A:
[25--7]
------------------------------------------------------------------------
P
L
I
K
E
K
G
Y
T
L
E
V
K
N
F
D
D
Y
I
L
P
N
E
A
L
N
N
G
E
I
D
A
N
L
F
Q
H
E
P
Y
L
K
E
A
V
K
A
K
-
G
Y
-
K
I
M
A
G
K
K
L
Y
V
C
P
A
I
L
Y
S
------
Y
----
K
--
I
K
S
V
D
E
F
K
K
-
G
D
T
I
A
I
S
N
N
P
S
S
C
S
K
N
L
R
Y
L
E
S
I
G
L
L
T
L
P
K
G
D
---
G
--
L
V
S
P
K
D
I
I
E
N
P
K
G
I
Q
F
K
E
L
--
D
---
I
A
Q
I
P
S
S
L
P
D
--
V
T
A
A
F
I
D
T
T
Y
A
V
P
A
G
L
D
A
K
-
K
N
G
I
Y
T
A
-
P
I
N
-
D
-
E
Y
-----
A
N
L
L
A
F
R
T
E
---
D
---
K
D
S
E
K
I
K
V
L
Q
D
V
L
T
S
D
K
A
R
S
L
I
E
E
K
Y
K
G
--------------------
34
HHSearch
75.39
28%
0
- C- -
-
3UP9
-
?
A:
[5--7]
---------------------------------------------
D
V
V
T
L
T
V
G
A
T
P
S
P
---
H
A
K
I
L
T
Y
I
N
D
-
N
L
A
A
D
A
G
I
K
L
D
I
V
E
Y
T
D
Y
V
Q
P
N
T
A
L
N
D
G
D
L
D
A
N
F
Y
Q
T
V
P
Y
L
E
N
A
E
K
Q
F
-
G
Y
-
N
F
E
A
G
E
G
I
H
L
E
P
L
G
V
F
S
------
N
----
K
--
H
K
S
L
D
E
L
-
P
D
G
G
T
I
G
I
I
S
D
T
A
N
Q
S
R
A
L
E
L
L
A
T
Q
G
L
V
S
I
-
P
E
G
------
D
-
V
N
I
N
T
V
T
K
L
K
N
F
D
F
R
E
V
--
E
---
G
P
Q
L
V
R
S
L
D
D
--
F
D
Y
A
V
I
N
G
N
F
A
Q
E
G
-
G
K
T
I
S
G
D
A
L
V
V
E
-
S
P
V
----
D
N
P
A
--
V
N
V
L
V
W
K
G
D
---
S
---
K
K
V
D
A
I
A
K
L
E
K
L
L
H
S
D
E
V
K
Q
Y
I
E
K
T
W
S
D
G
-------------------
11
PsiBlast_PDB
74.73
32%
0
- C- -
-
3UP9
-
?
A:
[33--10]
-----------------------------------------------------------------------------
A
G
I
K
L
D
I
V
E
Y
T
D
Y
V
Q
P
N
T
A
L
N
D
G
D
L
D
A
N
F
Y
Q
T
V
P
Y
L
E
N
A
E
K
Q
F
-
G
Y
-
N
F
E
A
G
E
G
I
H
L
E
P
L
G
V
F
S
------
N
----
K
--
H
K
S
L
D
E
L
P
D
-
G
G
T
I
G
I
I
S
D
T
A
N
Q
S
R
A
L
E
L
L
A
T
Q
G
L
V
S
I
P
E
G
D
--
V
N
--
I
N
T
V
T
K
L
----
K
N
F
D
F
R
E
V
--
E
---
G
P
Q
L
V
R
S
L
D
D
--
F
D
Y
A
V
I
N
G
N
F
A
Q
E
G
G
K
T
I
S
-
G
D
A
L
V
V
E
S
P
V
D
-
N
-
P
A
-----
V
N
V
L
V
W
K
G
D
---
S
---
K
K
V
D
A
I
A
K
L
E
K
L
L
H
S
D
E
V
K
Q
Y
I
E
K
T
W
----------------------
21
PsiBlast_CBE
72.37
35%
-57
- C7 -
-
4IB2
2
?
B:
[15-246]
--------------------------------------------------
V
A
A
S
A
T
-
P
---
H
A
E
I
L
E
Q
A
K
S
I
--
L
K
K
E
G
Y
Q
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
E
K
-
G
T
-
H
L
V
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
------
G
----
T
--
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
-
K
-
D
G
A
G
L
--
N
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
--
E
---
A
A
Q
V
A
R
V
T
G
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
A
-
K
D
A
L
A
Y
E
-
K
S
D
S
E
-
A
A
K
T
Y
--
V
N
I
I
A
V
K
E
G
---
N
---
E
K
E
E
K
I
Q
A
L
V
K
A
L
K
S
D
E
I
K
E
Y
I
E
K
T
Y
D
G
--------------------
4
PsiBlast_PDB
72.24
35%
-54
- C7 -
-
4IB2
2
?
A:
[15-246]
--------------------------------------------------
V
A
A
S
A
T
-
P
---
H
A
E
I
L
E
Q
A
K
S
I
--
L
K
K
E
G
Y
Q
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
E
K
-
G
T
-
H
L
V
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
------
G
----
T
--
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
-
K
-
D
G
A
G
L
--
N
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
--
E
---
A
A
Q
V
A
R
V
T
G
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
A
-
K
D
A
L
A
Y
E
-
K
S
D
S
E
-
A
A
K
T
Y
--
V
N
I
I
A
V
K
E
G
---
N
---
E
K
E
E
K
I
Q
A
L
V
K
A
L
K
S
D
E
I
K
E
Y
I
E
K
T
Y
D
G
--------------------
33
HHSearch
71.63
30%
0
- C- -
-
4GOT
-
A:
[4--3]
---------------------------------------------
G
K
K
E
I
V
V
A
A
T
K
T
P
---
H
A
E
I
L
K
E
A
-
E
-
P
L
L
K
E
K
G
Y
T
L
K
V
K
V
L
S
D
Y
K
M
Y
N
K
A
L
A
D
K
E
V
D
A
N
Y
F
Q
H
I
P
Y
L
E
Q
E
M
K
E
N
T
D
Y
-
K
L
V
N
A
G
A
V
H
L
E
P
F
G
I
Y
S
------
K
----
T
--
Y
K
S
L
K
D
L
-
P
D
G
A
T
I
I
L
T
N
N
V
A
E
Q
G
R
M
L
A
M
L
E
N
A
G
L
I
T
L
-
D
S
K
V
E
T
V
--
D
A
T
L
K
D
I
K
K
N
P
K
N
L
E
F
K
K
V
--
A
---
P
E
L
T
A
K
A
Y
E
N
KE
G
D
A
V
F
I
N
V
N
Y
A
I
Q
N
-
K
L
N
P
K
K
D
A
I
E
V
E
-
S
T
K
----
N
N
P
Y
--
A
N
I
I
A
V
R
K
G
---
E
---
E
D
S
A
K
I
K
A
L
M
E
V
L
H
S
K
K
I
K
D
F
I
E
K
K
Y
D
-
G
A
V
L
P
V
--------------
2
PsiBlast_PDB
71.62
35%
4
- C7 -
-
4QHQ
1
?
A:
[9-238]
-------------------------------------------------------
G
-
P
---
D
S
E
V
W
Q
V
V
Q
K
V
A
K
E
K
E
-
G
L
N
V
K
V
I
E
F
N
D
Y
V
Q
P
N
A
A
L
D
S
G
D
L
D
A
N
S
F
Q
H
Q
P
Y
L
D
S
Q
V
K
Q
R
-
G
Y
-
K
I
V
S
A
G
L
T
Y
I
S
P
I
G
V
Y
S
------
K
----
K
--
F
K
S
L
K
D
L
P
Q
-
G
A
K
L
A
V
P
N
D
P
S
N
E
N
R
A
L
L
L
L
Q
T
Q
G
V
I
K
L
-
K
A
G
A
G
T
G
G
N
N
A
T
V
L
D
I
A
E
N
P
K
K
L
K
I
S
E
L
--
D
---
A
A
Q
L
P
R
V
L
S
D
--
V
D
A
A
V
I
N
T
N
Y
A
L
A
A
N
L
Q
P
T
-
K
D
A
I
A
L
E
-
S
L
-----
T
S
P
Y
--
A
N
L
I
A
V
R
A
K
---
D
---
K
D
Q
P
W
V
K
K
L
V
K
A
Y
Q
S
P
E
V
K
E
F
I
K
K
Q
F
K
G
S
M
V
-----------------
22
Fugue
71.56
33%
34
- C7 -
-
1P99
1
?
A:
[40-294]
------------------------------------------------
K
V
T
I
G
V
A
S
-
N
---
D
T
K
A
W
E
K
V
K
--
E
L
A
K
K
D
D
I
D
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
H
-
K
G
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
------
D
----
K
--
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
-
K
K
D
F
G
L
---
A
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
--
D
---
A
Q
Q
T
A
R
A
L
S
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
-
N
D
P
I
F
L
E
-
K
S
N
S
D
-
A
V
K
P
Y
--
I
N
I
V
A
V
N
D
K
---
D
---
L
D
N
K
T
Y
A
K
I
V
E
L
Y
H
S
K
E
A
Q
K
A
L
Q
E
D
V
K
D
G
E
K
P
V
N
L
S
K
D
E
I
K
A
I
E
T
S
L
A
37
HHSearch
70.97
30%
10
- C7 -
-
1XS5
-
TPN32_TREPA
A:
[2-240]
----------------------------------------------
D
E
T
V
G
V
G
V
L
S
E
P
---
H
A
R
L
L
E
-
I
A
K
-
E
E
V
K
K
Q
H
I
E
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
E
H
-
N
G
-
D
L
V
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
------
R
----
T
--
Y
R
H
V
S
D
F
-
P
A
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
-
R
A
G
S
-
G
L
--
F
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
--
E
---
S
A
L
L
P
R
V
F
D
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
-
G
L
S
A
R
R
D
G
L
A
V
E
-
P
D
-----
A
S
A
Y
--
A
N
V
L
V
V
K
R
G
---
N
---
E
A
D
A
R
V
Q
A
V
L
R
A
L
C
G
G
R
V
R
T
Y
L
K
E
R
Y
K
G
G
E
V
A
P
A
--------------
6
PsiBlast_PDB
70.69
32%
-80
- C7 -
-
1XS5
-
TPN32_TREPA
A:
[24-237]
-------------------------------------------------------------------------
E
V
K
K
Q
H
I
E
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
E
H
-
N
G
-
D
L
V
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
------
R
----
T
--
Y
R
H
V
S
D
F
P
A
-
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
-
R
A
G
-
S
G
L
--
F
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
--
E
---
S
A
L
L
P
R
V
F
D
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
G
L
S
A
R
-
R
D
G
L
A
V
E
-
P
-
D
-
A
-
S
A
Y
----
A
N
V
L
V
V
K
R
G
---
N
---
E
A
D
A
R
V
Q
A
V
L
R
A
L
C
G
G
R
V
R
T
Y
L
K
E
R
Y
K
G
G
E
V
-----------------
5
PsiBlast_PDB
68.36
35%
21
- C7 -
-
1P99
1
?
A:
[40-270]
------------------------------------------------
K
V
T
I
G
V
A
S
-
N
---
D
T
K
A
W
E
K
V
K
E
L
--
A
K
K
D
D
I
D
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
H
-
K
G
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
------
D
----
K
--
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
-
K
K
D
F
G
L
A
---
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
--
D
---
A
Q
Q
T
A
R
A
L
S
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
-
N
D
P
I
F
L
E
-
K
S
N
-
S
D
A
V
K
P
Y
--
I
N
I
V
A
V
N
D
K
---
D
---
L
D
N
K
T
Y
A
K
I
V
E
L
Y
H
S
K
E
A
Q
K
A
L
Q
E
------------------------
40
HHSearch
68.34
34%
28
- C7 -
-
4IB2
2
?
A:
[7-251]
-------------------------------------------
S
E
D
A
K
T
I
K
V
A
A
S
A
T
P
---
H
A
E
I
L
E
-
Q
A
K
-
S
I
L
K
K
E
G
Y
Q
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
E
K
-
G
T
-
H
L
V
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
------
G
----
T
--
K
K
S
L
D
E
I
-
S
E
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
-
K
D
G
A
-
G
L
--
N
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
--
E
---
A
A
Q
V
A
R
V
T
G
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
-
G
Y
S
V
A
K
D
A
L
A
Y
E
-
K
S
D
-
S
E
A
A
K
T
Y
--
V
N
I
I
A
V
K
E
G
---
N
---
E
K
E
E
K
I
Q
A
L
V
K
A
L
K
S
D
E
I
K
E
Y
I
E
K
T
Y
D
-
G
A
V
I
P
F
--------------