@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLK9: (2017-11-03 )
MNEKQTRCPKCLTVYKVSLTQLTVAQGMVCCAKCNLNFNALTNLVNVEQPETVNSSALAHGSMQTRYMTHSHVLDIFDQKVENSNIDLLTYLNNLNYFHNEPINALPNLNLAEQATSPEQDNGKKHSWLYYTLWSSANLILILVFTFQILWFNPKLMQQSPAISHAFNYVCQILHCNKSAKQYQLLYIEKVKLRKIGTEHTQLSGVLINQNNKSIELPNLKLSFGKETDQEEIIFTPQQYLVENLRGIQRIPTNTPFRFQVELNKSKKSLVNYRLEIVHP
Atome Classification :
(20 SA)
.........10........20...--------.-------....-30......--..40-.......----.50------------........60.....---...70.------.......80.......-.90.....-------...100-...----------------------....110.......120........130..---------.....140.-......150---.......------------..160..----.....170-------..--------.....-..-------------180.....---------------------------------..-190------------..-----------------...-..----200........210...------.....-.220....---...-230.......240........250......----...260..------.....270--.........280-------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNEKQTRCP
K
C
L
T
V
Y
K
V
S
L
T
Q
L
T
V
--------
A
-------Q
G
M
V
-
C
C
A
KCNL
N
--
F
N
A
L
-
T
N
LVNVE----QPE------------TVN
S
S
A
LAHGS
M
Q
T
R
---
Y
M
T
H
S
H
------
V
L
D
I
F
D
Q
K
VENSN
I
D
L
-
L
T
YLNNL
N
-------
Y
F
HNEP-INA----------------------LPNLN
L
A
E
QATSPEQ-DNG
K
K
H
S
W
L
Y
Y
T
LW---------SSA
N
L
I
L
I
L
-
V
F
T
F
Q
I
L-----WFN
P
K
L
M------------QQSP
A
I
S
----
H
A
F
N
Y
V
---------
C
Q
--------
I
L
HCN-KS-------------A
K
Q
Y
Q
L
L
Y
---------------------------------
I
E
-
K
V
K
------------
L
R
-----------------KIG-TE----H-T
Q
L
S
G
V
L
INQ--NNK------SIELP-
N
L
K
L
SFGK---ETD-QE
E
I
I
FT
P
Q
Q
Y
L
-
V
E
N
L
R
G
I
Q
R--IPTNT
P
----
F
R
F
Q
V
E
LN------KS
K
K
S
L
----
V
N
Y
R
L
E
IVHP---------------------------
36
Fugue
66.98
19%
-15
- C1 -
-
4Q6O
5
?
A:
[21-437]
M
I
E
K
A
---
P
T
N
V
E
D
R
D
K
A
P
H
L
L
L
L
--------
A
GIQGDE
P
G
G
F
N
-
A
T
N
L
F
L
M
H
--
Y
S
V
L
-
K
G
L
V
E
V
V
PVLN
K
P
S
------------
M
L
R
N
H
R
G
L
Y
G
D
M
N
R
K
---
F
A
A
L
D
K
NDPE
Y
P
T
I
Q
E
I
K
S
L
I
A
K
P
S
I
D
A
-
V
L
H
L
H
D
G
G
G
------
Y
Y
R
P
V
Y
-
V
D
A
MLNPKRWGN
C
F
I
I
DQDEVKGAK
F
P
N
L
L
A
F
A
N
N
T
I
E
S
I
-
N
A
H
L
L
H
P
I
E
E
Y
H
L
K
N
TRT-----
A
Q
G
D
T
E
M
Q
K
-
A
L
T
F
Y
A
I
N
Q
KKS
A
F
A
N
E
A
S
------------
K
E
L
P
L
A
S
----
R
V
F
Y
H
L
---------
Q
A
--------
I
E
G
L
L
-
N
Q
L
NI
P
F
K
R
DFDLN
P
N
S
V
H
A
L
I
N
DKN
L
W
A
K
I
SSLPKMPLFNLRPKLNH
F
P
L
P
H
NTK
I
P
-
Q
I
P
------------
I
E
S
NAYI
V
G
L
V
K
N
KQ
E
V
F
L
K
Y
G
N
K
L
----
M
-
T
R
L
S
P
F
Y
I
E
F
--
D
P
S
LE
E
V
K
M
Q
I
D
N
K
-
D
Q
M
V
K
I
G
S
---
V
V
E
V
K
E
S
F
Y
I
H
A
M
D
N
I
-
R
A
N
V
I
G
F
S
V
--
S
N
E
N
K
P
NEAG
Y
T
I
K
F
K
D
F
------
Q
K
R
F
S
L
DKQE
R
I
Y
R
I
E
F
Y
K
N
NAFS
G
M
I
L
V
K
F
V---------------
29
Fugue
65.85
18%
8
- C4 -
-
5K4B
-
EIF3D_NASVI
A:
[3-368]
---
S
V
T
V
R
P
D
W
V
T
I
E
E
M
D
F
P
R
L
S
K
L
T
L
P
GVKE
G
-------
E
D
V
L
-
C
C
G
A
V
E
-
Y
--
Y
D
K
S
-
Y
D
R
V
N
V
K
----
N
E
K
P
L
Q
R
I
D
R
I
F
H
TV
T
T
T
D
D
P
V
I
R
K
L
S
K
T
E
GN
V
Y
A
T
D
A
I
------
L
A
T
I
M
C
C
T
R
S
N
Y
S
W
D
I
V
I
E
K
I
G
N
K
L
-------
F
F
D
K
R
D
-
N
T
E
----------------------
F
D
L
L
T
V
N
E
T
S
V
E
P
P
Q
-
D
D
G
N
S
L
N
S
-
P
R
N
L
A
---------
L
E
A
T
F
I
N
-
H
-
N
F
S
Q
Q
V
L
-----
K
S
N
E
P
R
Y
KFDEPNPFISEE
E
E
G
E
V
A
S
----
V
A
Y
R
Y
R
---------
K
W
D
LNNG
I
T
L
I
A
R
C
E
H
D
A
-------------
V
M
Q
T
Q
F
L
T
---------------------------------
I
K
-
A
L
N
E
W
D
SKLANGVEW
R
R
-----------------
K
L
D
-
T
Q
----
R
-
G
A
V
L
A
N
E
L
R
N
--
N
A
C
------
K
L
A
K
W
-
T
V
Q
A
L
L
A
G
----
S
D
-
Q
L
K
F
G
Y
V
S
R
A
S
V
R
D
S
S
K
H
V
I
L
E
--
T
Q
Q
Y
K
P
----
N
E
F
A
T
Q
I
N
LN
M
---
D
N
A
W
G
I
----
L
R
C
I
I
D
I
C
M
N
QKD
G
K
Y
L
I
M
K
DPNKP
M
I
R
L
Y
DIPDNTF
28
Fugue
65.38
21%
-
* C5 *
-
4Q58
-
ITB4_HUMAN (first)
D:
[1127-1320]
L
G
A
P
Q
N
P
N
A
K
A
A
G
S
R
K
I
H
F
N
W
L
P
-------------------------------------------------
P
S
------------
G
K
P
M
G
Y
R
V
K
Y
W
I
Q
G
D
---
S
E
S
E
A
H
------
L
L
D
S
K
V
P
S
V
E
L
T
N
L
Y
P
Y
C
D
Y
E
M
K
V
C
-------
A
Y
G
A
Q
G
-
E
G
P
----------------------
Y
S
S
L
V
S
C
R
T
H
Q
E
V
P
S
-
E
P
G
R
----
L
A
F
N
V
V
---------
S
S
T
---------
V
T
Q
L
S
-----
W
A
E
P
A
E
T
----------------------------------------------------
N
-
G
E
-------------
I
T
A
Y
E
V
C
Y
---------------------------------
G
------------------------------------------------------
L
V
N
D
--
D
N
R
------
P
I
G
-
P
-
M
K
K
V
L
V
D
N
---
P
K
N
-
R
--------
M
L
L
-
I
E
N
L
R
--------
E
S
Q
P
----
Y
R
Y
T
V
K
A
R
N
GA
G
W
G
P
E
R
E
A
I
----
I
N
L
A
---
T
Q
P
---------------------------
37
Fugue
51.26
15%
-15
- C2 -
-
5CW4
2
BRCC3_CAMFO
A:
[6-251]
----------------
S
S
L
Q
K
V
E
L
--------
Q
-------
T
D
V
Y
M
V
C
L
Q
H
A
L
S
TE
N
F
E
V
M
G
L
L
I
G
N
F
----
A
C
G
------------
I
A
K
I
S
A
V
I
---
I
L
R
R
---
L
D
K
K
K
D
------
R
V
E
I
S
S
E
Q
L
L
K
A
A
A
E
A
-
E
R
L
T
V
E
L
N
R
P
M
R
VL
G
W
Y
H
S
H
P
H
I
T
V
----------------------
C
P
S
H
V
D
V
R
T
Q
A
T
Y
Q
T
M
D
H
S
-------------------------
F
V
G
L
-
I
F
S
V
------------
F
S
E
------------
G
K
E
S
K
E
H
----
E
I
F
L
N
C
---------
F
Q
--------
S
D
--
N
-
G
E
-------------
A
T
E
I
P
L
E
I
---------------------------------
V
H
-
T
P
D
------------
I
S
-----------------
D
R
C
-
L
R
----
T
M
T
D
L
S
K
I
L
V
Q
E
--
E
E
D
M
-----
A
E
A
C
K
-
D
----------
H
P
D
-
V
L
A
S
I
H
N
N
A
V
R
T
-
R
A
L
I
H
I
T
D
I
I
T
K
P
L
V
Q
T
----
F
E
K
R
I
A
L
N
------
K
L
R
A
T
H
----
L
Q
R
Q
L
Q
E
L
Q
K
---------------------------
25
HHSearch
43.16
18%
-152
- C6 -
-
2HF1
-
Y3345_CHRVO
A:
[7-40]
---
E
I
L
V
C
P
L
C
K
G
P
L
V
F
D
K
-------------
S
-------
K
D
E
L
-
I
C
K
G
D
R
L
A
--
F
P
I
K
-
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
42.60
16%
-145
- C6 -
-
3VPB
-
LYSW_SULTO
E:
[1-37]
--
M
V
V
L
K
C
P
V
C
N
G
D
V
N
V
P
D
D
-
A
-
L
--------
P
-------
G
E
I
V
-
E
H
-
E
C
G
A
Q
--
L
E
V
Y
-
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
42.56
15%
-141
* C6 *
-
2JNY
-
?
A:
[9-42]
---
E
V
L
A
C
P
K
D
K
G
P
L
R
Y
L
E
-------------
S
-------
E
Q
L
L
-
V
N
E
R
L
N
L
A
--
Y
R
I
D
-
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
42.52
17%
-200
- C6 -
-
5K2M
-
?
E:
[2-36]
-----
V
E
C
P
V
C
G
S
E
I
E
I
G
E
V
E
-----------
L
-------
H
Q
I
V
-
E
C
P
V
C
G
A
E
--
L
E
V
V
-
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
42.35
10%
-15
- C5 -
-
3SY6
2
?
A:
[8-279]
------
S
G
E
K
T
L
A
V
V
S
A
S
S
D
D
R
P
S
--------
T
-------
R
G
I
I
------------
N
D
N
-
T
Y
A
L
G
V
F
----
R
T
T
------------
A
N
T
Y
A
P
L
Y
N
V
K
H
I
Y
S
---
G
G
E
W
G
A
------
D
D
V
I
---
K
V
D
Y
R
N
A
S
F
-
F
A
Y
Y
P
------------
Y
H
T
A
-
T
G
N
----------------------
Y
A
G
L
A
G
G
T
T
L
T
L
Q
A
Q
-
L
F
N
A
G
E
D
I
C
Y
G
A
G
E
A
SGGGPVSV
Y
N
P
F
V
E
F
L
N
M
K
H
A
Y
A
R
L
-----
R
L
T
L
T
R
G
------------
E
K
F
D
K
T
K
----
K
C
N
I
Q
N
---------
I
T
--------
F
K
S
N
N
-
A
N
-------------
F
Y
L
T
R
S
L
D
---------------------------------
I
A
-
S
T
A
------------
G
A
-----------------
T
G
G
-
S
A
V
AA
G
Y
-
V
H
N
P
N
V
N
I
A
T
--
G
K
S
------
V
T
Y
E
Y
M
F
P
P
Q
P
L
D
G
---
S
K
L
-
T
I
L
V
T
V
D
G
V
T
R
S
-
C
D
I
S
T
L
G
S
S
--
L
D
S
G
K
Y
----
Y
G
V
S
L
T
F
T
------
D
V
G
I
I
L
----
S
S
A
V
V
T
V
N
N
F
---------------------------
12
HHSearch
41.61
17%
-198
- C6 -
-
5K2M
-
?
F:
[2-36]
-----
V
E
C
P
V
C
G
S
E
I
E
I
G
E
V
E
-----------
L
-------
H
Q
I
V
-
E
C
P
V
C
G
A
E
--
L
E
V
V
-
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
41.42
24%
-170
- C6 -
-
2JS4
-
Y2007_BORBR
A:
[7-40]
---
D
I
L
V
C
P
V
C
K
G
R
L
E
F
Q
R
-------------
A
-------
Q
A
E
L
-
V
C
N
A
D
R
L
A
--
F
P
V
R
-
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
39.73
9%
-162
- C6 -
-
2JR6
-
Y874_NEIMA
A:
[7-40]
---
D
I
L
V
C
P
V
T
K
G
R
L
E
Y
H
Q
-------------
D
-------
K
Q
E
L
-
W
S
R
Q
A
K
L
A
--
Y
P
I
K
-
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
38.79
16%
-89
- C6 -
-
3WWN
-
?
B:
[1-37]
---
M
V
G
T
C
P
E
C
G
A
E
L
R
L
E
N
P
E
-----------
L
-------
G
E
L
V
-
V
C
E
D
C
G
A
E
--
L
E
V
V
-
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
36.47
22%
4
- C5 -
-
2HW4
16
PHP14_HUMAN
A:
[18-141]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----
Y
F
Q
S
M
D
L
------------
A
L
I
P
D
V
D
I
D
S
D
G
V
F
K
Y
V
L
I
R
V
H
SAE
S
K
E
--------
I
V
R
G
Y
-
K
W
-------------
A
E
Y
H
A
D
I
Y
---------------------------------
D
K
V
S
G
D
------------
M
Q
-----------------
K
Q
G
-
C
D
----
C
-
E
C
L
G
G
G
R
I
S
H
Q
S
Q
D
K
------
K
I
H
V
Y
-
G
Y
S
M
A
Y
G
P
AQ
H
A
I
S
-
T
E
K
I
K
A
K
Y
P
D
Y
E
-
V
T
W
A
N
-----------------------------------------------------------------------------
4
PsiBlast_PDB
36.45
30%
-89
- C6 -
-
4PB0
1
?
H:
[27-97]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
F
S
I
F
-----
W
M
N
--
W
V
------------
R
Q
S
P
--
E
----
K
G
L
E
W
V
---------
A
E
--------
V
---
R
-
L
K
-------------
S
N
N
Y
A
T
H
Y
---------------------------------
A
E
-
S
V
K
------------
G
R
-----------------
F
T
I
-
S
R
----
D
-
D
S
K
S
G
V
Y
L
Q
M
--
N
N
L
------
R
A
E
-----------------------------------------------------------------------------------------------------------------
7
HHSearch
36.37
16%
-85
- C6 -
-
3WWL
-
LYSW_THET8
A:
[1-37]
---
M
V
G
T
C
P
E
C
G
A
E
L
R
L
E
N
P
E
-----------
L
-------
G
E
L
V
-
V
C
E
D
C
G
A
E
--
L
E
V
V
-
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
36.19
24%
-108
- C6 -
-
4QIW
-
RPOP_THEKO
W:
[8-38]
-------
C
A
K
C
G
K
E
V
E
L
D
L
A
T
-------------------
A
R
E
V
-
R
C
P
Y
C
G
S
K
--
I
L
Y
K
-
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
34.81
22%
-103
- C6 -
-
2NB9
-
?
A:
[1-49]
---
M
I
L
T
C
P
E
C
A
S
R
Y
F
V
D
D
S
K
V
G
P
--------
D
-------
G
R
V
V
-
R
C
A
S
C
G
N
R
--
W
T
A
F
-
K
D
E
A
E
L
E
----
L
V
P
------------
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.67
24%
-116
- C6 -
-
2NB9
-
?
A:
[1-42]
---
M
I
L
T
C
P
E
C
A
S
R
Y
F
V
D
D
S
K
V
G
P
--------
D
-------
G
R
V
V
-
R
C
A
S
C
G
N
R
--
W
T
A
F
-
K
D
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
31.81
30%
-91
- C6 -
-
1PFT
-
TF2B_PYRFU
A:
[1-37]
M
V
N
K
Q
K
V
C
P
A
C
E
S
A
E
L
I
Y
D
----
P
--------
E
-------
R
G
E
I
-
V
C
A
K
C
G
Y
V
--
I
E
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------