@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLM1: (2017-11-03 )
MPKTLQFGITNFEIDFKDLVMNTMIKNKRFENDVEFRGADIKDSRAVVILLHGRRQNADTIYELAEKIGFTDITYILPLAPELTWYPRGFMRDLEDNQPYLSVALERIHYIITDLKNQNIKPENIFLMGFSQGACIVSQYLWENPQKLGGVIAFTGGLFGPELTYTSHEGLPINGTQLIFTGGKEDSWVPEQRVRDTAALFEKLGGNVTTKIYSGRDHLVSDEEVELAKTLLNI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60.....--..--.-----70--........80-----------.--------.-----------------.-----------...-.-.90.----.------------......100..-----.---.------...110----...-...-.120.......130.......140..-.....150......-----.160....------------...----170--....----...180.......190.......200..--.--.--...210---.........220....-----...230..-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MPK
T
L
Q
FGI
T
N
F
E
I
D
F
K
D
L
V
M
N
T
M
IKNKRFENDVEFRGADIKDS
R
A
V
V
I
L
L
HGRRQN
A
D
T
I
Y
E
L
A
E
--KI--G-----FT--
D
I
T
Y
I
LPLAP-----------E--------L-----------------T-----------WYP-
R
-
G
F
M
R
----D------------LEDNQ
P
Y
L
S
V
A
-----
L
---
E
------
R
I
H
Y
I
I
----
T
DL-KNQ-NIKPE
N
I
F
L
M
GFSQ
G
A
C
I
V
S
Q
Y
L
WE
N
-
P
Q
KL
G
G
V
I
A
FTGGL-----FGPE
L
T
YT------------SHE----GLP--ING
T
----
Q
L
I
F
TGGKEDSWV
P
E
Q
R
V
R
D
T
A
A
L
F
E
K
L--G--G--
N
V
T
T
-----
K
I
YSGRDHLVS
D
E
E
V
E
-----
L
A
K
T
L
LNI-----
22
HHSearch
99.14
32%
-140
- C2 -
-
4H0C
2
?
B:
[9-210]
-------------------------------
K
Q
I
I
T
S
G
V
P
V
Q
R
A
K
K
A
V
V
M
L
H
G
R
G
G
T
A
A
D
I
I
S
L
Q
K
--
V
L
--
K
-----
L
D
--
E
M
A
I
Y
A
P
Q
A
T
-----------
N
--------
N
-----------------
S
-----------
W
Y
P
-
Y
-
S
F
M
A
----
P
------------
V
Q
Q
N
Q
P
A
L
D
S
A
-----
L
---
A
------
L
V
G
E
V
V
----
A
E
I
-
E
A
Q
-
G
I
P
A
E
Q
I
Y
F
A
G
F
S
Q
G
A
C
L
T
L
E
Y
T
T
R
N
-
A
R
K
Y
G
G
I
I
A
F
T
G
G
L
-----
I
G
Q
E
L
A
I
G
------------
N
Y
-----
K
G
D
--
F
K
Q
T
----
P
V
F
I
S
T
G
N
P
D
P
H
V
P
V
S
R
V
Q
E
S
V
T
I
L
E
D
M
--
N
--
A
--
A
V
S
Q
-----
V
V
Y
P
G
R
P
H
T
I
S
G
D
E
I
Q
-----
L
V
N
N
T
I
L
K
-----
21
HHSearch
98.45
32%
-140
- C2 -
-
4H0C
3
?
A:
[9-210]
-------------------------------
K
Q
I
I
T
S
G
V
P
V
Q
R
A
K
K
A
V
V
M
L
H
G
R
G
G
T
A
A
D
I
I
S
L
Q
K
--
V
L
--
K
-----
L
D
--
E
M
A
I
Y
A
P
Q
A
T
-----------
N
--------
N
-----------------
S
-----------
W
Y
P
-
Y
-
S
F
M
A
----
P
------------
V
Q
Q
N
Q
P
A
L
D
S
A
-----
L
---
A
------
L
V
G
E
V
V
----
A
E
I
-
E
A
Q
-
G
I
P
A
E
Q
I
Y
F
A
G
F
S
Q
G
A
C
L
T
L
E
Y
T
T
R
N
-
A
R
K
Y
G
G
I
I
A
F
T
G
G
L
-----
I
G
Q
E
L
A
I
G
------------
N
Y
-----
K
G
D
--
F
K
Q
T
----
P
V
F
I
S
T
G
N
P
D
P
H
V
P
V
S
R
V
Q
E
S
V
T
I
L
E
D
M
--
N
--
A
--
A
V
S
Q
-----
V
V
Y
P
G
R
P
H
T
I
S
G
D
E
I
Q
-----
L
V
N
N
T
I
L
K
-----
1
PsiBlast_PDB
95.06
33%
-140
- C2 -
-
4H0C
3
?
A:
[15-203]
-------------------------------------
G
V
P
V
Q
R
A
K
K
A
V
V
M
L
H
G
R
G
G
T
A
A
D
I
I
S
L
Q
K
--
V
L
--
K
-----
L
D
--
E
M
A
I
Y
A
P
Q
A
T
-----------
N
--------
N
-----------------
S
-----------
W
Y
P
-
Y
-
S
F
M
A
----
P
------------
V
Q
Q
N
Q
P
A
L
D
S
A
-----
L
---
A
------
L
V
G
E
V
V
----
A
E
I
-
E
A
Q
-
G
I
P
A
E
Q
I
Y
F
A
G
F
S
Q
G
A
C
L
T
L
E
Y
T
T
R
N
-
A
R
K
Y
G
G
I
I
A
F
T
G
G
L
-----
I
G
Q
E
L
A
I
G
------------
N
Y
K
----
G
-
D
--
F
K
Q
T
----
P
V
F
I
S
T
G
N
P
D
P
H
V
P
V
S
R
V
Q
E
S
V
T
I
L
E
D
M
--
N
--
A
--
A
V
S
Q
-----
V
V
Y
P
G
R
P
H
T
I
S
G
D
E
I
Q
-----
L
------------
9
PsiBlast_PDB
76.22
26%
-48
- C2 -
-
5SYN
2
LYPA2_HUMAN
A:
[25-224]
---------------------------------------------
A
A
V
I
F
L
H
G
L
G
D
T
G
H
S
W
A
D
A
L
S
--
T
I
--
R
-----
L
P
--
H
V
K
Y
I
C
P
H
A
P
-----------
R
--------
I
PVTLNMKMVMP------
S
-----------
W
F
D
L
M
-
G
L
S
P
----
D
------------
A
P
E
D
E
A
G
I
K
K
A
-----
A
---
E
------
N
I
K
A
L
I
----
E
H
E
-
M
K
N
-
G
I
P
A
N
R
I
V
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
T
C
-
P
H
P
L
A
G
I
V
A
L
S
C
W
L
------------
P
------------
L
H
R
----
A
F
P
QA
A
N
G
S
AKD
L
A
I
L
Q
C
H
G
E
L
D
P
M
V
P
---
V
R
F
G
A
L
T
A
E
K
L
--
R
--
S
--
V
V
T
P
AR
V
Q
F
K
T
Y
P
G
V
M
H
S
S
C
P
Q
E
M
A
-----
A
V
K
E
F
L
-------
11
PsiBlast_PDB
75.57
26%
-24
- C2 -
-
5SYM
8
LYPA1_HUMAN
A:
[18-223]
-----------------------------------------
R
K
A
T
A
A
V
I
F
L
H
G
L
G
D
T
G
H
G
W
A
E
A
F
A
--
G
I
--
R
-----
S
S
--
H
I
K
Y
I
C
P
H
A
P
VRPVTLNMNVA
M
--------
P
-----------------
S
-----------
W
F
D
-
I
I
G
L
S
P
----
D
------------
S
Q
E
D
E
S
G
I
K
Q
A
-----
A
---
E
------
N
I
K
A
L
I
----
D
Q
E
-
V
K
N
-
G
I
P
S
N
R
I
I
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
T
T
-
Q
Q
K
L
A
G
V
T
A
L
S
C
W
L
--------
P
L
R
A
S
------------
F
P
Q
----
G
-
P
--
I
G
G
A
NRD
I
S
I
L
Q
C
H
G
D
C
D
P
L
V
P
L
M
F
G
S
L
T
V
E
K
L
K
T
L
VN
P
--
A
--
N
V
T
F
-----
K
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
-----
D
V
K
Q
F
I
D
------
12
PsiBlast_PDB
75.11
26%
-23
- C2 -
-
1FJ2
-
LYPA1_HUMAN
A:
[20-225]
-----------------------------------------
R
K
A
T
A
A
V
I
F
L
H
G
L
G
D
T
G
H
G
W
A
E
A
F
A
--
G
I
--
R
-----
S
S
--
H
I
K
Y
I
C
P
H
A
P
V
R
P
V
TLNMNVA
M
--------
P
-----------------
S
-----------
W
F
D
-
I
I
G
L
S
P
----
D
------------
S
Q
E
D
E
S
G
I
K
Q
A
-----
A
---
E
------
N
I
K
A
L
I
----
D
Q
E
-
V
K
N
-
G
I
P
S
N
R
I
I
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
T
T
-
Q
Q
K
L
A
G
V
T
A
L
S
C
W
L
--------
P
L
R
A
S
------------
F
P
Q
----
G
-
P
--
I
G
G
A
NRD
I
S
I
L
Q
C
H
G
D
C
D
P
L
V
P
L
M
F
G
S
L
T
V
E
K
L
K
T
L
VN
P
--
A
--
N
V
T
F
-----
K
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
-----
D
V
K
Q
F
I
D
------
42
Fugue
73.24
24%
-11
- C2 -
-
1FJ2
-
LYPA1_HUMAN
A:
[3-231]
M
D
P
E
F
M
S
T
P
L
P
A
I
V
P
A
A
------------------------
R
K
A
T
A
A
V
I
F
L
H
G
L
G
D
T
G
H
G
W
A
E
A
F
A
--
G
I
--
R
-----
S
S
--
H
I
K
Y
I
C
P
H
A
P
-----------
V
--------
R
-----------------
P
V
TLNMNVAMPS
W
F
D
-
I
-
I
G
L
S
P---
D
------------
S
Q
E
D
E
S
G
I
K
Q
A
-----
A
---
E
------
N
I
K
A
L
I
----
D
Q
E
-
V
K
N
-
G
I
P
S
N
R
I
I
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
-
T
T
Q
Q
K
L
A
G
V
T
A
L
S
C
W
L
-----
P
L
R
A
S
F
P
Q
------------
G
P
I
----
G
G
A
--
N
R
D
I
----
S
I
L
Q
C
H
G
D
C
D
P
L
V
P
L
M
F
G
S
L
T
V
E
K
L
K
T
L
--
V
NP
A
--
N
V
T
F
-----
K
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
-----
D
V
K
Q
F
I
D
K
L
L
PPI
3
PsiBlast_PDB
73.06
24%
-20
- C2 -
-
5DWD
-
?
A:
[40-237]
-------------------------------------------
A
K
S
L
V
V
L
L
H
G
Y
G
S
D
G
R
D
L
I
A
L
G
Q
F
W
R
D
--
S
-----
F
P
--
D
T
M
F
V
A
P
N
A
P
-----------
H
--------
V
-----------------
C
GGNPFGYE---
W
F
P
-
L
---------
D
------------
L
E
R
D
R
T
L
A
R
L
A
G
----
A
---
E
------
T
A
H
P
V
L
D
A
F
L
A
D
L
-
W
A
Q
T
G
L
G
P
A
D
T
I
L
V
G
F
S
Q
G
A
M
M
A
L
Y
T
G
L
R
L
-
P
E
P
L
K
A
I
I
A
F
S
G
L
I
-----
V
A
P
E
K
L
E
A
------------
E
I
A
----
S
K
P
----------
P
V
L
L
I
H
G
D
L
D
D
V
V
P
V
I
G
S
E
T
A
L
P
K
L
I
D
L
--
G
--
I
--
D
A
R
L
-----
H
I
S
Q
G
S
G
H
T
I
A
Q
D
G
L
D
-----
T
A
T
A
F
L
R
------
23
HHSearch
71.16
25%
-11
- C2 -
-
1FJ2
-
LYPA1_HUMAN
B:
[6-225]
---------------------------
E
F
M
S
T
P
L
P
A
I
V
P
A
A
R
K
A
T
A
A
V
I
F
L
H
G
L
G
D
T
G
H
G
W
A
E
A
F
A
--
G
I
--
R
-----
S
S
--
H
I
K
Y
I
C
P
H
A
P
-----------
V
--------
R
PVTLNMNVAMPSWFDII
G
-----------
L
S
P
-
D
-
S
Q
---------------------
E
D
E
S
G
I
K
Q
A
-----
A
---
E
------
N
I
K
A
L
I
----
D
Q
E
-
V
K
N
-
G
I
P
S
N
R
I
I
L
G
G
F
S
Q
G
G
A
L
S
L
Y
T
A
L
T
T
-
Q
Q
K
L
A
G
V
T
A
L
S
C
W
L
-----
P
L
R
A
S
F
P
Q
------------
G
P
I
----
G
G
A
--
N
R
D
I
----
S
I
L
Q
C
H
G
D
C
D
P
L
V
P
L
M
F
G
S
L
T
V
E
K
L
K
T
L
--
V
NP
A
--
N
V
T
F
-----
K
T
Y
E
G
M
M
H
S
S
C
Q
Q
E
M
M
-----
D
V
K
Q
F
I
D
------
26
HHSearch
69.96
20%
-37
- C2 -
-
5DWD
2
?
B:
[23-238]
--------------------------
T
E
P
V
K
L
S
G
P
M
L
P
A
V
S
G
A
A
K
S
L
V
V
L
L
H
G
Y
G
S
D
G
R
D
L
I
A
L
G
Q
--
F
W
--
R
-----
D
S
F
P
D
T
M
F
V
A
P
N
A
P
-----------
H
--------
V
-----------------
C
-----------
G
G
N
-
P
-
F
G
Y
E
----
W
FPLDLERDR---
T
L
A
R
L
A
G
A
E
T
A
-----
H
---
P
------
V
L
D
A
F
L
----
A
D
L
W
A
Q
T
-
G
L
G
P
A
D
T
I
L
V
G
F
S
Q
G
A
M
M
A
L
Y
T
G
L
R
L
-
P
E
P
L
K
A
I
I
A
F
S
G
L
I
-----
V
A
P
E
K
L
E
--------------------
A
E
I
--
A
S
K
P
----
P
V
L
L
I
H
G
D
L
D
D
V
V
P
V
I
G
S
E
T
A
L
P
K
L
I
D
L
--
G
--
I
--
D
A
R
L
-----
H
I
S
Q
G
S
G
H
T
I
A
Q
D
G
L
D
-----
T
A
T
A
F
L
R
E
-----
43
Fugue
68.82
24%
-27
- C2 -
-
1AUO
-
EST2_PSEFL
A:
[1-218]
M
T
E
P
L
I
L
Q
P
A
-------------------------------
K
P
A
D
A
C
V
I
W
L
H
G
L
G
A
D
R
Y
D
F
M
P
V
A
E
--
A
L
Q
E
S
-----
L
L
--
T
T
R
F
V
L
P
Q
A
P
-----------
T
--------
R
-----------------
P
VTINGGYEMPS
W
Y
D
-
I
-
K
A
M
S
P---
A
------------
R
S
I
S
L
E
E
L
E
V
S
-----
A
---
K
------
M
V
T
D
L
I
----
E
A
Q
-
K
R
T
-
G
I
D
A
S
R
I
F
L
A
G
F
S
Q
G
G
A
V
V
F
H
T
A
F
I
N
W
Q
G
P
L
G
G
V
I
A
L
S
T
Y
A
-------
P
T
F
G
D
E
------------
L
E
L
----
S
A
S
--
Q
Q
R
I
----
P
A
L
C
L
H
G
Q
Y
D
D
V
V
Q
N
A
M
G
R
S
A
F
E
H
L
K
S
R
--
G
--
V
--
T
V
T
W
-----
Q
E
Y
P
M
G
H
E
V
L
P
Q
E
I
H
D
-----
I
G
A
W
L
A
A
R
L
G---
2
PsiBlast_PDB
67.98
26%
-44
- C2 -
-
4F21
-
?
A:
[34-244]
-----------------------------------------
K
Q
A
R
F
C
V
I
W
L
H
--
G
A
D
G
H
D
F
V
D
I
V
N
YF
D
V
--
S
-----
L
D
--
E
I
R
F
I
F
P
H
A
D
-----------
I
--------
I
PVTINMGMQMR------
A
-----------
W
Y
D
-----
I
K
----
S
------------
L
---
S
L
N
R
V
V
D
-----
V
---
E
I
N
S
S
I
A
K
V
N
K
L
I
----
D
S
Q
-
V
N
Q
--
I
A
S
E
N
I
I
L
A
G
F
S
Q
G
G
I
I
A
T
Y
T
A
I
T
S
-
Q
R
K
L
G
G
I
M
A
L
S
T
Y
L
P
AWDN
F
K
G
K
I
T
-
S
------------
I
N
K
----
G
L
P
--
I
---------
L
V
C
H
G
T
D
D
Q
V
L
P
E
V
L
G
H
D
L
S
D
K
L
K
V
S
--
G
--
F
--
A
N
E
Y
-----
K
H
Y
V
G
M
Q
H
S
V
C
M
E
E
I
K
D
I
S
N
F
I
A
K
T
F
--------
24
HHSearch
66.77
20%
-15
- C2 -
-
5KRE
1
LYPL1_HUMAN
A:
[10-228]
------------------------------
V
L
Q
R
C
I
V
S
P
A
G
-
R
H
S
A
S
L
I
F
L
H
G
S
G
D
S
G
Q
G
L
R
M
W
I
K
--
Q
V
--
L
NQDLT
F
Q
--
H
I
K
I
I
Y
P
T
A
P
-----------
P
--------
R
-----------------
S
-----------
Y
T
P
-
M
-
K
G
G
I
----
S
NVWFDRFKITND
C
P
E
H
L
E
S
I
D
V
M
-----
C
---
Q
------
V
L
T
D
L
I
----
D
E
E
-
V
K
S
-
G
I
K
K
N
R
I
L
I
G
G
F
S
M
G
G
C
M
A
M
H
L
A
Y
R
N
-
H
Q
D
V
A
G
V
F
A
L
S
S
F
L
-----
N
K
A
S
A
V
Y
Q
------------
A
L
Q
----
K
S
N
--
G
V
L
P
----
E
L
F
Q
C
H
G
T
A
D
E
L
V
L
H
S
W
A
E
E
T
N
S
M
L
K
S
L
--
G
--
V
--
T
T
K
F
-----
H
S
F
P
N
V
Y
H
E
L
S
K
T
E
L
D
-----
I
L
K
L
W
I
L
------
6
PsiBlast_PDB
65.70
20%
7
- C2 -
-
4FHZ
1
?
A:
[58-263]
------------------------------------
R
G
A
A
P
G
E
A
T
S
L
V
V
F
L
H
G
Y
G
A
D
G
A
D
L
L
G
L
A
E
--
P
L
--
A
PH---
L
P
--
G
T
A
F
V
A
P
D
A
P
-----------
E
PCRANGFG
F
-----------------
Q
-----------
W
F
P
-
I
-
P
W
L
D
----
G
------------
S
S
E
T
A
A
A
E
G
M
A
-----
A
A
A
R
D
------
L
D
A
F
L
D
----
E
R
L
-
A
E
E
-
G
L
P
P
E
A
L
A
L
V
G
F
S
Q
G
T
M
M
A
L
H
V
A
P
R
R
-
A
E
E
I
A
G
I
V
G
F
S
G
R
L
-----
L
A
P
E
R
L
A
E
------------
E
A
R
----
S
K
P
----------
P
V
L
L
V
H
G
D
A
D
P
V
V
P
F
A
D
M
S
L
A
G
E
A
L
A
E
A
--
G
--
F
--
T
T
Y
G
-----
H
V
M
K
G
T
G
H
G
I
A
P
D
G
L
S
-----
V
A
L
A
F
L
K
------
28
HHSearch
65.10
24%
-26
- C2 -
-
1AUR
1
EST2_PSEFL
A:
[5-214]
----------------------------------
L
I
L
Q
P
A
-
K
P
A
D
A
C
V
I
W
L
H
G
L
G
A
D
R
Y
D
F
M
P
V
A
E
--
A
L
--
Q
-----
E
S
LL
T
T
R
F
V
L
P
Q
A
P
-----------
T
--------
R
-----------------
P
-----------
V
T
I
-
N
-
G
G
Y
E
----
M
PSW
Y
D
I
K
A
MSPA
R
S
I
S
L
E
E
L
E
V
S
-----
A
---
K
------
M
V
T
D
L
I
----
E
A
Q
-
K
R
T
-
G
I
D
A
S
R
I
F
L
A
G
F
S
Q
G
G
A
V
V
F
H
T
A
F
I
N
W
Q
G
P
L
G
G
V
I
A
L
S
T
Y
A
-----
P
T
F
G
D
E
L
E
-------------
L
-----
S
A
S
--
Q
Q
R
I
----
P
A
L
C
L
H
G
Q
Y
D
D
V
V
Q
N
A
M
G
R
S
A
F
E
H
L
K
S
R
--
G
--
V
--
T
V
T
W
-----
Q
E
Y
P
M
-
G
H
E
V
L
P
Q
E
I
H
-----
D
I
G
A
W
L
A
------
29
HHSearch
64.45
24%
-28
- C2 -
-
1AUO
-
EST2_PSEFL
B:
[5-214]
----------------------------------
L
I
L
Q
P
A
-
K
P
A
D
A
C
V
I
W
L
H
G
L
G
A
D
R
Y
D
F
M
P
V
A
E
--
A
L
--
Q
-----
E
S
LL
T
T
R
F
V
L
P
Q
A
P
-----------
T
--------
R
-----------------
P
-----------
V
T
I
-
N
-
G
G
Y
E
----
M
PSWYDIKAMSPA
R
S
I
S
L
E
E
L
E
V
S
-----
A
---
K
------
M
V
T
D
L
I
----
E
A
Q
-
K
R
T
-
G
I
D
A
S
R
I
F
L
A
G
F
S
Q
G
G
A
V
V
F
H
T
A
F
I
N
W
Q
G
P
L
G
G
V
I
A
L
S
T
Y
A
-----
P
T
F
G
D
E
L
E
-------------
L
-----
S
A
S
--
Q
Q
R
I
----
P
A
L
C
L
H
G
Q
Y
D
D
V
V
Q
N
A
M
G
R
S
A
F
E
H
L
K
S
R
--
G
--
V
--
T
V
T
W
-----
Q
E
Y
P
M
-
G
H
E
V
L
P
Q
E
I
H
-----
D
I
G
A
W
L
A
------
10
PsiBlast_PDB
64.41
20%
3
- C2 -
-
4FTW
2
?
A:
[58-263]
------------------------------------
R
G
A
A
P
G
E
A
T
S
L
V
V
F
L
H
G
Y
G
A
D
G
A
D
L
L
G
L
A
E
--
P
L
--
A
PH---
L
P
--
G
T
A
F
V
A
P
D
A
P
-----------
E
PCRACGFG
F
-----------------
Q
-----------
W
F
P
-
I
-
P
W
L
D
----
G
------------
S
S
E
T
A
A
A
E
G
M
A
A
A
A
R
D
L
---
D
------
A
F
H
D
------
E
R
L
-
A
E
E
-
G
L
P
P
E
A
L
A
L
V
G
F
S
Q
G
T
M
M
A
L
H
V
A
P
R
R
-
A
E
E
I
A
G
I
V
G
F
S
G
R
L
-----
L
A
P
E
R
L
A
E
------------
E
A
R
----
S
K
P
----------
P
V
L
L
V
H
G
D
A
D
P
V
V
P
F
A
D
M
S
L
A
G
E
A
L
A
E
A
--
G
--
F
--
T
T
Y
G
-----
H
V
M
K
G
T
G
H
G
I
A
P
D
G
L
S
-----
V
A
L
A
F
L
K
------
25
HHSearch
64.04
20%
-12
- C- -
-
3U0V
-
LYPL1_HUMAN
A:
[9-226]
-------------------------------
L
Q
R
C
I
V
S
P
A
G
-
R
H
S
A
S
L
I
F
L
H
G
S
G
D
S
G
Q
G
L
R
M
W
I
K
--
Q
V
--
L
NQDLT
F
Q
--
H
I
K
I
I
Y
P
T
A
P
-----------
P
--------
R
-----------------
S
-----------
Y
T
P
-
M
-
K
G
G
I
----
S
NVWFDRFKITND
C
P
E
H
L
E
S
I
D
V
M
-----
C
---
Q
------
V
L
T
D
L
I
----
D
E
E
-
V
K
S
-
G
I
K
K
N
R
I
L
I
G
G
F
S
M
G
G
C
M
A
M
H
L
A
Y
R
N
-
H
Q
D
V
A
G
V
F
A
L
S
S
F
L
-----
N
K
A
S
A
V
Y
Q
------------
A
L
Q
----
K
S
N
--
G
V
L
P
----
E
L
F
Q
C
H
G
T
A
D
E
L
V
L
H
S
W
A
E
E
T
N
S
M
L
K
S
L
--
G
--
V
--
T
T
K
F
-----
H
S
F
P
N
V
Y
H
E
L
S
K
T
E
L
D
-----
I
L
K
L
W
I
L
------
39
HHSearch
63.11
19%
-9
- C2 -
-
4FTW
2
?
A:
[53-263]
-------------------------------
L
T
F
G
R
R
G
A
A
P
G
E
A
T
S
L
V
V
F
L
H
G
Y
G
A
D
G
A
D
L
L
G
L
A
E
--
P
L
--
A
-----
P
H
LP
G
T
A
F
V
A
P
D
A
P
EPCRAC-----
G
--------
F
-----------------
G
-----------
F
Q
W
-
F
-
P
I
P
W
LDGS
S
------------
E
T
A
A
A
E
G
M
A
A
A
-----
A
---
R
------
D
L
D
A
F
H
----
D
E
R
L
A
E
E
-
G
L
P
P
E
A
L
A
L
V
G
F
S
Q
G
T
M
M
A
L
H
V
A
P
R
R
-
A
E
E
I
A
G
I
V
G
F
S
G
R
L
-----
L
A
P
E
R
L
A
--------------------
E
E
A
--
R
S
K
P
----
P
V
L
L
V
H
G
D
A
D
P
V
V
P
F
A
D
M
S
L
A
G
E
A
L
A
E
A
--
G
--
F
--
T
T
Y
G
-----
H
V
M
K
G
T
G
H
G
I
A
P
D
G
L
S
-----
V
A
L
A
F
L
K
------
35
HHSearch
62.49
20%
-42
- C2 -
-
1UFO
-
?
B:
[14-232]
--------------------------------
S
V
L
A
R
I
P
E
--
A
P
K
A
L
L
L
A
L
H
G
L
Q
G
S
K
E
H
I
L
A
L
L
P
--
G
Y
--
A
-----
E
R
--
G
F
L
L
L
A
F
D
A
P
-----------
R
--------
H
-----------------
G
-----------
E
R
E
-
G
-
P
P
P
S
----
S
KSPRY-------
V
E
E
V
Y
R
V
A
L
G
F
-----
K
---
E
------
E
A
R
R
V
A
----
E
E
A
-
E
R
R
---
F
G
L
P
L
F
L
A
G
G
S
L
G
A
F
V
A
H
L
L
L
A
E
G
-
F
-
R
P
R
G
V
L
A
F
I
G
S
G
-----
F
P
M
K
L
P
Q
G
QVVEDPGVLALY
Q
A
P
PATR
G
E
A
--
Y
G
G
V
----
P
L
L
H
L
H
G
S
R
D
H
I
V
P
L
A
R
M
E
K
T
L
E
A
L
R
P
H
--
Y
--
P
EG
R
L
A
R
-----
F
V
E
E
G
A
G
H
T
L
T
P
L
M
A
R
-----
V
G
L
A
F
L
E
------