@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLP6: (2017-11-03 )
MTIMFVRKRNSALFTVILLGSILSGCQVVNVKQQALNVTIANERNSILTQGKLSEASLNVLSMSGQEAKACTDSPDTCVNQLKNLPQILDEQLLSAASEMYLAKAMALSDSSECKISRFTKHKPTEEQKVIQNKYDECLDQQLSLLDKSIRYSYAYLFSTKRQPTDRIFDNRQVQIRDFYNQAIAKMVSVYDLRYPQKNVVEPQIHIGKSVYSIDFEFHRQLSGQKLEKLISSYNLNFSGLRTINRRDGFGSEFVAVFPSSGKEDINEYILDPLNYSYKNGVNPNIHHARYLAATIVAEPKHAKTIQEIINDPEFVIRVYDPYRTDNINVAGKQYPLATNFSAPYGLWLAENNLGVAAYLSLIDRDQHLTMPHLYMLEPYNPNKKIIVLVHGLASSPEAWIALTNDVMGDTVLRDNYQVWQVFYSTNMPILESRFQIYALLKQAFGSLNPSDPAAHDAVLVGHSMGGIISRLLVSDADITKPALEMMTIRQQNRFKKHPMVTERLQMHSISNFDRTIFLASPHRGTDYADRWFTLAARKIIRLPGAFLSAVTTSLTTENLDIKDFLNNIDNGLIQNGPSDLSHQSKFMELTENINPHQGLIFHSIMGNITKSDDPNVITDGIVPYKSAHLEGAKSEKVLPGGHSIQLTPQAVLELRRILREHLVEHGLYKP
Atome Classification :
(20 SA)
----------.........10---------------------.........20........30--....--.....40........50........60........70........80..-------......90---........100----.......110.......-----------------120.......130.......----140.......150....-...160.......-170.......180.......190...--..-------------------------------------..200..--.------------------....210.......220.......230.......240.......250.......260..--..-...270.......280........290.......300.......310.....-------..----320-------------------------.......------------.330.......340.......350.......360.......370.......380.--------......390.....-----.--------.-----.400.......-410..-.....420----.......430----.---------.---------....-...440------------------------.......450.......460.......470.....-..480.....--------..------490.......500---....-...510.......---520..-..-...530.....-----....540..----..--..----.550.......560.......----570..----......580--........590..----.....600.--....----..610---------------------------.......620.--......630......-.640.......650...-....660.......670-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------
M
T
I
M
F
V
RKRN----------------------S
A
L
F
T
V
I
L
L
G
S
I
LSG
C
Q
V
V
N
---
V
K
Q
Q
--
A
L
N
V
T
I
ANERNSILTQGKLSEA
S
L
N
V
L
SMSGQEAKACTDS
P
D
T
C
V
N
Q
L
K
-------
N
L
P
Q
I
L
D
E
---
Q
L
L
S
A
A
S
E
M
Y
L
----
A
K
A
MALSDSSE
C
K
I
S
R
F-----------------TKHKP
T
E
E
Q
K
V
I
Q
N
K
Y
D
E
C
L
----
D
Q
Q
L
S
L
L
D
K
S
I
R
Y
S
Y
A
Y
-
L
FSTKRQP
T
D
RIF-DN
R
Q
V
Q
I
R
D
F
Y
N
Q
A
I
A
K
M
V
S
V
Y
DLRY--PQ-------------------------------------KNVVEP
Q
--
I
------------------
H
IG
K
S
V
Y
S
I
D
F
E
F
H
R
Q
LS
G
Q
K
L
E
K
L
I
S
SYNLNFSG
L
R
T
INRRDGFGS
E
F
V
A
VFPSS
G
K
E
--
D
I
-
N
E
Y
ILDPLNYSYKN-GVNPNI
H
H
A
R
Y
L
A
A
T
IVAEP
K
H
A
K
T
I
Q
E
I
INDP
E
F
V
I
-------
R
V
----YD--------------------------PYRTDN
I
------------
N
VAGKQYPLATNFSAP
Y
G
L
W
L
AENNL
G
V
A
A
Y
L
S
L
IDRDQHLTMP
H
L
Y
M
LEPYNPN--------
K
K
I
I
V
L
V
H-GLASS-----P--------
E
-----
A
W
I
A
LTNDVMG-D
T
V
LR-DN
Y
Q
V
W
Q
V
----
F
YSTNM
P
I
------
L
---------
E
---------
S
R
F
Q
-
I
Y
A
L
L
K
------------------------
Q
A
FGSLNPSDPAAH
D
A
V
L
VGH
S
M
G
G
I
I
S
R
L
L
VSDA-DIT
K
P
A
L
E
M
M
--------
T
I
------
R
Q
QNRFKKHP
M
V
T
---
E
R
L
Q
-
M
HSISNF
D
R
T
I
F
L
---ASPHR-GT-
D
Y
A
D
--
R
W
F
T
L
-----
A
A
R
K
I
I
RL
P
----
G
A
--
F
L
----
S
A
V
T
TSLTTENL
D
I
K
D
F
L
N
NI----D-NGL----IQNGPSD
L
---
S
H
Q
S
K
F
M
E
L
TENI----NPHQ
G
L
I
F
H
--
S
I
MG----NITKS---------------------------DDPNVITDGIV--PY
K
S
AHLEGAKSEKV-LPGG
H
S
I
Q
L
T
P
Q
A
V
L
E
L
-
R
R
I
L
R
E
H
L
V
E
HGLYKP--
48
Fugue
56.68
17%
64
- C2 -
-
4ZUZ
-
?
A:
[8-864]
D
V
I
K
F
K
EPER
C
D
Y
L
Y
V
D
E
N
N
K
V
H
I
L
L
P
IVGGDE
I
G
L
D
N
TC
Q
T
A
V
E
L
I
T
F
F
Y
G
S
A
H
S
G
V
T
K
Y
S
---
A
E
H
Q
L
S
E
Y
K
R
Q
L
E
E
D
I
K
A
I
N
S
Q
K
K
I
S
P
H
A
Y
D
D
L
L
K
E
K
I
E
R
L
Q
Q
I
E
K
Y
I
E
L
I
Q
V
L
K
K
QYDEQN
D
I
R
Q
L
R
T
G
GIP
Q
L
P
S
G
V
K
E
I
I
K
S
SEN
A
F
A
V
R
L
S
P
Y
D
N
D
K
F
T
R
F
DDPL
F
N
V
K
R
N
ISKYDTP
S
R
Q
A
P
I
P
I
Y
E
G
L
G
Y
R
L
R
S
T
L
FPED
K
T
P
T
P
I
N
K
K
S
L
R
D
K
V
K
S
-
T
V
L
S
H
Y
K
D
E
D
R
I
D
G
E
K
K
D
E
K
L
N
E
L
I
T
N
L
Q
N
E
L
V
K
E
L
V
K
S
D
--
P
Q
YSKLSLSKDPRG
K
E
I
N
YDYLVNSLMLVDNDSE
I
G
D
W
I
D
T
I
L
D
A
T
--
V
DSTVWAVQASSPFYQGAK
E
I
S
S
D
R
D
A
D
K
I
S
I
R
V
Q
Y
L
L
A
E
A
N
I
Y
C
K
T
N
K
L
S
D
A
N
F
G
E
F
F
D
K
E
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
GA
D
I
-
E
P
I
I
Y
D
Y
I
N
S
N
H
A
E
L
G
L
K
S
P
L
T
-
G
K
Q
Q
Q
E
I
T
D
K
F
T
K
H
Y
N
T
I
K
E
S
P
H
F
D
E
F
F
V
A
D
PDKKG
N
I
----
F
S
H
QGRISCH
F
L
D
F
F
T
R
Q
T
KGKHPLGDL
A
S
H
Q
E
A
L
Q
E
GTSNRLHHKN
E
V
V
A
Q
G
Y
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
N
K
--
P
K
E
L
L
D
Y
L
V
A
T
S
P
T
G
V
P
N
Y
S
M
L
S
K
E
T
Q
N
Y
I
A
Y
NRN
W
P
A
I
Q
K
E
L
E
-
K
A
T
S
I
-----
P
--------
E
-----
S
Q
K
Q
D
L
S
R
L
L
S
R
D
N
L
Q
H
-
D
N
L
S
A
I
T
W
----
S
K
Y
S
S
K
P
L
------
L
---------
D
---------
V
E
L
N
-
K
I
A
E
G
L
------------------------
E
L
T
A
K
I
Y
N
E
K
R
G
R
E
-----
W
W
F
A
G
S
R
N
E
A
R
K
T
Q
C
E
-
E
L
Q
R
V
S
K
E
I
N
--------
T
L
------
L
Q
S
E
S
L
T
K
S
Q
V
L
E
---
K
V
L
N
S
I
E
T
L
D
K
I
D
R
D
I
S
A
---
E
S
N
W
F
-
Q
S
-
T
L
Q
K
E
V
R
L
F
R
D
-----
Q
L
K
D
I
C
Q
L
D
----
K
Y
--
Y
F
----
K
S
-
T
K
L
D
E
I
I
S
L
E
M
E
E
Q
F
Q
K
I
----
Q
-
D
P
A
----
V
Q
Q
I
V
R
D
L
PSH
C
H
N
D
E
A
I
E
F
F
K
T
L
----
N
P
E
E
A
A
K
V
A
--
S
Y
L
S
L
E
Y
R
E
I
N
K
S
---------------------------
T
D
K
K
T
L
L
E
Q
D
I
--
P
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
-
K
E
E
K
A
I
D
E
Q
V
H
E
K
L
S
Q
L
A
D
K
I
A
P
E
H
F
T
R
N
N
I
I
K
W
S
T
49
Fugue
51.02
18%
13
* C6 *
-
4C3X
7
?
A:
[23-530]
------------------
D
W
----------------------
T
S
E
C
D
V
L
V
V
G
S
G
G
G
A
L
T
G
A
Y
---
T
A
A
A
--
Q
G
L
T
T
I
V
L
E
K
T
D
R
F
--
G
G
T
S
A
Y
S
G
A
S
I
W
L
P
G
T
Q
V
Q
E
R
A
G
L
P
D
S
---------------------------
T
E
N
A
R
T
Y
L
----
R
A
L
L
G
-----------------------------------
D
A
E
S
E
R
Q
D
A
Y
V
E
T
A
----
P
A
V
V
A
L
L
E
Q
N
P
N
I
E
F
E
F
R
A
F
P
D
Y
Y
K
A
E
G
R
M
D
-
T
G
R
S
I
N
P
L
D
L
D
P
A
D
I
----------------------------------------------------------------------------------
G
D
L
A
G
K
V
R
P
E
L
D
Q
D
R
T
G
Q
D
H
A
P
------------
G
P
M
I
G
G
R
A
L
I
G
R
L
L
A
A
V
Q
S
T
G
K
A
--
E
L
R
T
E
S
V
L
T
S
L
I
V
E
D
G
-----------
R
V
V
G
A
E
V
E
S
G
----
G
E
T
Q
R
I
K
A
N
R
G
V
L
M
-------
A
A
GGIE
G
N
--------------------------
A
E
M
R
E
Q
A
------------
G
T
P
G
K
A
I
W
S
M
G
P
F
G
A
N
T
G
D
A
I
S
A
G
I
A
V
G
G
A
T
A
L
L
---
D
Q
A
W
F
C
P
G
V
E
-----
Q
P
D
--------
G
S
A
A
F
M
V
--
G
V
R
G
G
------------------------
L
V
V
D
S
A
G
-
E
R
Y
L
N
-
E
S
L
------------------------------------------------
P
Y
D
Q
F
G
------------------------
R
A
M
D
A
H
D
D
N
G
S
A
V
P
S
F
M
I
F
D
S
R
E
G
G
G
L
P
A
I
C
I
P
N
T
-
A
-
P
A
K
H
L
E
A
G
--------
T
W
------
V
G
A
D
T
L
E
E
L
A
A
K
T
GLP
A
D
A
L
-
R
S
T
V
E
K
F
N
D
A
A
K
L
GVD
E
E
F
H
R
-
G
E
-
D
P
Y
D
--
A
F
F
C
-------------------------------------
P
P
N
G
G
A
N
A
A
L
T
A
I
----
E
-
N
G
P
----
F
Y
A
A
R
I
V
L
---
S
D
L
G
T
---------------
K
G
G
L
V
T
--
D
V
N
G
----
R
V
L
R
A
---------------------------
D
G
S
A
I
D
--
G
L
Y
A
A
G
N
T
S
A
S
L
S
G
R
F
Y
P
G
P
G
V
P
L
G
T
A
M
V
F
S
Y
R
A
A
Q
D
M
-
A
K
----------------
29
HHSearch
47.36
19%
-122
- C5 -
-
1WOM
6
RSBQ_BACSU
A:
[18-111]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
--------
K
A
S
I
M
F
A
P
-
G
F
G
C
D
-----
Q
--------
S
-----
V
W
N
A
V
A
P
A
F
-------
E
-
E
D
H
R
V
I
L
F
----
D
Y
V
G
S
G
H
S
------
D
LRAYDLNRY
Q
---------
T
L
D
G
-
Y
A
Q
D
V
L
------------------------
D
V
C
E
A
L
D
-----
L
K
E
T
V
F
V
G
H
S
V
G
A
L
I
G
M
L
A
S
I
R
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
44.20
25%
-129
- C5 -
-
3V48
1
RUTD_ECOSE
A:
[5-103]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
L
S
P
P
P
Y
A
D
--------
A
P
V
V
V
L
I
S
-
G
L
G
G
S
-----
G
--------
S
-----
Y
W
L
P
Q
L
A
V
L
-------
E
-
Q
E
Y
Q
V
V
C
Y
----
D
Q
R
G
T
G
N
N
------
P
D
T
L
A
ED---
Y
---------
S
I
A
Q
-
M
A
A
E
L
H
------------------------
Q
A
L
V
A
A
G
-----
I
E
H
Y
A
V
V
G
H
A
L
G
A
L
V
G
M
Q
L
A
L
D
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
44.07
25%
-129
- C5 -
-
3V48
1
RUTD_ECOSE
B:
[5-103]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
L
S
P
P
P
Y
A
D
--------
A
P
V
V
V
L
I
S
-
G
L
G
G
S
-----
G
--------
S
-----
Y
W
L
P
Q
L
A
V
L
-------
E
-
Q
E
Y
Q
V
V
C
Y
----
D
Q
R
G
T
G
N
N
------
P
DTLAED---
Y
---------
S
I
A
Q
-
M
A
A
E
L
H
------------------------
Q
A
L
V
A
A
G
-----
I
E
H
Y
A
V
V
G
H
A
L
G
A
L
V
G
M
Q
L
A
L
D
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
43.94
15%
-81
- C5 -
-
1I6W
-
ESTA_BACSU
A:
[3-181]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
N
P
V
V
M
V
H
-
G
I
G
G
A
-----
S
--------
F
-----
N
F
A
G
I
K
S
Y
L
V
S
-
Q
------
G
W
S
R
D
K
L
----
Y
A
V
D
F
W
D
K
------
T
---------
G
---------
T
N
Y
N
-
N
G
P
V
L
S
------------------------
R
F
V
Q
K
V
L
D
E
T
G
A
K
K
-
V
D
I
V
A
H
S
M
G
G
A
N
T
L
Y
Y
I
K
N
L
-
D
G
G
N
K
V
A
N
V
V
--------
T
L
------
G
G
A
N
R
L
T
T
G
K
A
L
P
---
G
--------
T
D
P
N
Q
K
I
L
Y
---
T
S
I
Y
S
-
S
A
-
D
--------
M
I
-----
V
M
N
Y
L
S
R
L
D
----
G
A
--
R
N
----
V
Q
I
H
G
V
G
H
I
G
L
L
Y
S
S
Q
V
N
S
L
I
----
K
-
E
G
L
----
N
G
G
G
Q
N
T
N
----------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
43.75
18%
6
- C5 -
-
2HIH
-
LIP_STAHY
A:
[43-362]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
N
P
E
N
P
K
N
--------
K
D
P
F
V
F
V
H
-
G
F
T
G
F
-----
V
GEVAAKGE
N
-----
Y
W
G
G
T
K
A
N
L
R
---
N
H
L
R
K
A
G
Y
E
T
Y
E
A
----
S
V
S
A
L
A
S
N
------
H
---------
E
---------
R
A
V
E
-
L
Y
Y
Y
L
K
GGRVDYG
A
A
H
S
E
K
Y
GHERYGKTYE
G
V
L
K
D
W
K
----
P
G
H
P
V
H
F
I
G
H
S
M
G
G
Q
T
I
R
L
L
E
H
Y
L
R
F
G
D
K
---------------
A
------
E
I
A
Y
Q
Q
Q
H
G
G
I
I
S
---
E
L
F
K
-
G
G
Q
D
N
M
V
T
S
I
T
T
I
---
A
T
P
H
N
-
G
T
-
H
A
S
D
--
D
I
G
N
T
P
T
I
R
N
I
L
Y
S
F
A
Q
M
S
----
S
H
L
G
T
I
DFGM
D
H
W
G
F
-
K
R
K
D
G
E
S
L
T
D
Y
N
K
R
I
A
E
SK
I
-
W
D
S
----
E
D
T
G
L
Y
D
L
---
T
R
E
G
A
-
E
K
I
N
Q
K
T
----
E
L
N
P
N
I
Y
Y
K
--
T
Y
T
G
----
V
A
T
H
E
T
Q
LG
K
H
I
A
D
LGMEFTK
I
L
T
G
N
Y
I
G
S
VD
D
I
L
W
R
P
N
D
G
L
V
--
S
E
I
S
S
Q
H
P
S
D
------------------------------------------
21
HHSearch
43.34
18%
11
- C5 -
-
2HIH
-
LIP_STAHY
B:
[43-362]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
N
P
E
N
P
K
N
--------
K
D
P
F
V
F
V
H
-
G
F
T
G
F
-----
V
GEVAAKGE
N
-----
Y
W
G
G
T
K
A
N
L
R
---
N
H
L
R
K
A
G
Y
E
T
Y
E
A
----
S
V
S
A
L
A
S
N
------
H
---------
E
---------
R
A
V
E
-
L
Y
Y
Y
L
K
GGRVDYGAAHSEKYGHERYGKTYE
G
V
L
K
D
W
K
----
P
G
H
P
V
H
F
I
G
H
S
M
G
G
Q
T
I
R
L
L
E
H
Y
L
R
F
G
D
K
---------------
A
------
E
I
A
Y
Q
Q
Q
H
G
G
I
I
S
---
E
L
F
K
-
G
G
Q
D
N
M
V
T
S
I
T
T
I
---
A
T
P
H
N
-
G
T
-
H
A
S
D
--
D
I
G
N
T
PTIRN
I
L
Y
S
F
A
Q
M
S
----
S
H
LG
T
I
DFGM
D
H
W
G
F
-
K
R
K
D
G
E
S
L
T
D
Y
N
K
R
I
AESK
I
-
W
D
S
----
E
D
T
G
L
Y
D
L
---
T
R
E
G
A
-
E
K
I
N
Q
K
T
----
E
L
N
P
N
I
Y
Y
K
--
T
Y
T
G
----
V
A
T
H
E
TQLGKHIADLGMEFTKILTGNYIGSVD
D
I
L
W
R
P
N
D
G
L
V
--
S
E
I
S
S
Q
H
P
S
D
------------------------------------------
40
HHSearch
43.28
18%
-128
- C5 -
-
5A62
-
?
A:
[20-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
R
--------
S
Y
P
L
V
L
I
H
-
P
I
G
G
N
-----
I
--------
L
-----
I
W
D
Y
E
I
Q
L
L
L
------
K
-
S
G
F
R
V
I
A
Y
----
E
L
R
G
H
H
R
T
NMGKTG
A
---------
Y
---------
T
M
Q
D
-
L
I
D
D
L
R
------------------------
R
L
L
E
H
L
N
-----
I
G
K
C
T
I
I
G
H
S
I
G
G
I
I
S
S
M
Y
A
A
Q
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
43.17
20%
-46
- C5 -
-
4HS9
3
?
A:
[21-136]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
T
--------
K
Y
P
I
V
L
V
H
-
G
L
A
G
F
-----
S
--------
E
IVGFP
Y
F
Y
G
I
A
D
A
L
T
------
Q
-
D
G
H
Q
V
F
T
A
----
S
L
S
A
F
N
S
N
------
E
---------
V
---------
R
G
K
Q
-
L
W
Q
F
V
Q
------------------------
T
I
L
Q
E
T
Q
-----
T
K
K
V
N
F
I
G
H
S
Q
G
P
L
A
C
R
Y
V
A
A
N
Y
---------------------------------------------------
P
D
S
V
A
S
V
T
S
I
---
N
G
V
N
H
-
G
S
-
E
I
A
D
--
L
Y
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
42.94
16%
12
- C6 -
-
4Z2T
1
?
A:
[11-591]
--------AE
T
D
V
L
I
V
G
A
G
P
----------------------
A
G
A
M
S
A
T
L
L
A
S
L
G
I
R
S
L
M
I
N
RWR
S
T
S
P
--
G
P
R
S
H
I
I
N
Q
R
T
M
E
I
L
R
D
I
G
L
E
E
S
A
K
S
L
A
V
P
K
E
Y
M
G
E
H
V
Y
A
T
S
L
A
G
E
E
F
G
-------
R
I
P
----------------
A
W
A
----
S
H
P
Q
A
H
A
E
H
E
L
A
S
P
S
R
Y
-----------------
C
D
--------
L
P
Q
L
Y
F
E
P
M
V
----
V
S
E
A
A
L
R
G
A
D
V
R
F
L
T
E
Y
-
L
G
H
V
E
D
Q
-------
D
G
V
T
A
R
L
L
D
H
V
S
G
A
E
Y
E
V
R
A
K
Y
I
I
G
A
DG
A
H
-------------------------------------
S
L
V
A
Q
N
A
G
L
P
------------------
F
E
G
Q
M
G
G
S
I
N
I
E
F
S
A
D
L
S
S
L
C
E
H
R
K
G
D
M
Y
Y
M
F
V
A
A
L
R
M
I
R
P
W
N
----
K
W
I
C
V
W
G
E
I
T
K
E
--
E
A
-
K
K
I
I
H
E
I
I
G
T
D
----------------
E
I
P
V
E
V
G
P
I
S
T
W
T
I
N
Q
Q
Y
A
V
R
N
T
S
G
-------
R
V
----
F
C
--------------------------
M
G
D
A
--
V
------------
H
R
H
T
P
M
G
G
L
G
L
N
T
S
V
Q
D
A
Y
N
L
A
W
K
L
A
L
V
L
K
G
T
A
------
A
P
T
L
L
D
S
Y
D
A
E
R
S
P
V
A
--------
K
Q
I
V
E
R
A
F
K
S
L
S
T
F
-----
P
--------
P
-----
V
F
E
A
L
-----------------------------
S
L
P
P
------
A
---------
P
---------
T
E
S
E
-
M
A
E
A
L
V
------------------------
R
L
---
K
D
A
S
E
E
G
A
K
R
R
A
A
L
R
K
A
M
D
A
T
I
I
G
L
G
-------
G
G
H
G
V
E
L
N
-------------------
Q
R
Y
V
S
R
A
V
F
P
---
D
G
T
P
-
D
P
G
F
V
R
D
Q
E
F
F
Y
Q
---
A
S
T
R
P
-
G
A
-
H
L
P
H
--
V
W
L
T
E
-----
N
Q
R
R
I
S
T
L
D
L
C
GK
G
R
--
F
T
----
L
L
T
G
L
S
G
A
A
W
K
H
E
A
E
Q
V
S
Q
S
L
----
G
-
I
E
L
K
V
C
V
I
G
P
G
Q
E
F
V
---
D
T
Y
G
E
Y
A
K
I
S
E
-
I
----
G
E
S
G
A
L
L
V
R
--
P
D
M
F
----
I
A
F
R
A
---------------------------
K
D
A
-----------------------------------
S
R
E
G
L
E
Q
L
-
N
V
A
V
K
S
I
L
G
R
--------
35
HHSearch
41.90
14%
-137
- C5 -
-
1M33
1
BIOH_ECOLI
A:
[10-96]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
G
--------
N
V
H
L
V
L
L
H
-
G
W
G
L
N
-----
A
--------
E
-----
V
W
R
C
I
D
E
E
L
-------
S
-
S
H
F
T
L
H
L
V
----
D
L
P
G
F
G
R
S
------
R
G--------
F
---------
G
A
L
S
-
L
A
D
M
A
E
------------------------
A
V
L
Q
Q
A
------
P
D
K
A
I
W
L
G
W
S
L
G
G
L
V
A
S
Q
I
A
L
T
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
41.42
18%
-13
- C5 -
-
1M33
3
BIOH_ECOLI
A:
[3-258]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
W
W
Q
T
K
G
Q
G
--------
N
V
H
L
V
L
L
H
-
G
W
G
L
N
-----
A
--------
E
-----
V
W
R
C
I
-------
D
E
E
L
S
-
S
H
F
T
L
H
L
V
DLPG
F
G
R
S
R
G
F
G
------
A
---------
L
---------
S
L
A
D
M
A
E
A
V
L
Q
------------------------
Q
A
P
D
K
----------
A
I
W
L
G
W
S
L
G
G
L
V
A
S
Q
I
A
L
T
H
-
P
E
R
V
R
A
L
V
T
V
--------
A
S
SPCF
S
A
R
D
E
W
P
G
I
K
P
D
V
L
A
---
G
F
Q
Q
-
Q
L
S
D
D
Q
Q
R
T
V
E
R
F
---
L
A
L
Q
T
M
G
T
-
E
T
A
R
--
Q
D
A
R
A
-----
L
K
K
T
V
L
A
L
P
M---
P
E
--
V
D
----
V
L
N
G
G
L
E
I
L
K
T
V
D
L
R
Q
P
L
Q
N
V
----
S
M
P
F
L
----
R
L
Y
G
Y
L
D
G
---
L
V
P
R
K
V
V
P
L
D
K
L
W
----
P
H
S
E
S
Y
I
F
A
--
K
A
-
A
----
H
A
P
F
I
---------------------------
S
H
P
A
E
F
C
H
L
L
V
--
A
L
K
Q
R
V
G
S
--------------------------------------------
38
HHSearch
41.30
18%
-130
- C5 -
-
5DNW
2
?
A:
[20-113]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
--------
D
T
T
V
V
L
G
H
-
G
F
G
T
D
-----
Q
--------
S
-----
V
W
K
H
L
V
P
Y
L
-------
V
-
D
S
Y
R
V
L
L
Y
----
D
N
M
G
A
G
S
T
------
N
PEYFHFERY
S
---------
T
L
Q
G
-
Y
A
H
D
L
L
------------------------
V
I
L
H
E
F
N
-----
I
R
S
C
I
F
V
G
H
S
L
S
A
M
T
G
A
I
A
S
I
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
40.81
29%
0
- C5 -
-
1YS1
1
LIP_BURCE
X:
[4-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
A
T
--------
R
Y
P
I
I
L
V
H
-
G
L
T
G
T
-----
D
KYAGVL--
E
-----
Y
W
Y
G
I
Q
E
D
L
Q
------
Q
-
R
G
A
T
V
Y
V
A
----
N
L
S
G
F
Q
S
D
DGP---
N
---------
G
---------
R
G
E
Q
-
L
L
A
Y
V
K
------------------------
T
V
L
A
A
T
G
-----
A
T
K
V
N
L
V
G
H
S
Q
G
G
L
T
S
R
Y
V
A
A
V
A
---------------------------------------------------
P
D
L
V
A
S
V
T
T
I
---
G
T
P
H
R
-
G
S
-
E
F
A
D
--
F
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
40.42
16%
-109
- C5 -
-
3QVM
-
?
A:
[25-119]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
G
--------
E
K
T
V
L
L
A
H
-
G
F
G
C
D
-----
Q
--------
N
-----
M
W
R
F
M
L
P
E
L
-------
E
-
K
Q
F
T
V
I
V
F
----
D
Y
V
G
S
G
Q
S
------
D
LESFSTKRY
S
---------
S
L
E
G
-
Y
A
K
D
V
E
------------------------
E
I
L
V
A
L
D
-----
L
V
N
V
S
I
I
G
H
S
V
S
S
I
I
A
G
I
A
S
T
H
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
40.30
24%
-22
- C5 -
-
1EX9
1
LIP_PSEAE
A:
[2-119]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
T
Q
T
--------
K
Y
P
I
V
L
A
H
-
G
M
L
G
F
DNILG
V
--------
D
-----
Y
W
F
G
I
P
S
A
L
R
------
R
-
D
G
A
Q
V
Y
V
T
----
E
V
S
Q
L
D
T
S
------
E
---------
V
---------
R
G
E
Q
-
L
L
Q
Q
V
E
------------------------
E
I
V
A
L
S
G
-----
Q
P
K
V
N
L
I
G
H
S
H
G
G
P
T
I
R
Y
V
A
A
V
R
---------------------------------------------------
P
D
L
I
A
S
A
T
S
V
---
G
A
P
H
K
-
G
S
-
D
T
A
D
--
F
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
40.29
21%
-125
- C5 -
-
3W06
4
KAI2_ARATH
A:
[16-110]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
G
--------
E
A
T
I
V
L
G
H
-
G
F
G
T
D
-----
Q
--------
S
-----
V
W
K
H
L
V
P
H
L
-------
V
-
D
D
Y
R
V
V
L
Y
----
D
N
M
G
A
G
T
T
------
N
---------
P
DYFDFDRYS
N
L
E
G
-
Y
S
F
D
L
I
------------------------
A
I
L
E
D
L
K
-----
I
E
S
C
I
F
V
G
H
S
V
S
A
M
I
G
V
L
A
S
L
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
39.30
16%
-106
- C5 -
-
3QVM
-
?
B:
[25-119]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
G
--------
E
K
T
V
L
L
A
H
-
G
F
G
C
D
-----
Q
--------
N
-----
M
W
R
F
M
L
P
E
L
-------
E
-
K
Q
F
T
V
I
V
F
----
D
Y
V
G
S
G
Q
S
------
D
LESFSTKRY
S
---------
S
L
E
G
-
Y
A
K
D
V
E
------------------------
E
I
L
V
A
L
D
-----
L
V
N
V
S
I
I
G
H
S
V
S
S
I
I
A
G
I
A
S
T
H
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
39.26
15%
-13
- C5 -
-
1EX9
1
LIP_PSEAE
A:
[1-285]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
Y
T
Q
T
--------
K
Y
P
I
V
L
A
H
-
G
M
L
G
F
-----
D
--------
N
-----
I
L
G
V
D
Y
W
F
G
I
P
-
S
A
L
R
R
-
D
G
A
Q
V
Y
V
T
----
E
V
S
Q
L
D
T
S
------
E
---------
V
---------
R
G
E
Q
-
L
L
Q
Q
V
E
------------------------
E
I
V
A
L
S
G
-----
Q
P
K
V
N
L
I
G
H
S
H
G
G
P
T
I
R
Y
V
A
A
V
R
-
P
D
L
I
A
S
A
T
S
V
GAPHKGS
D
T
A
------
D
F
L
R
Q
I
P
P
G
S
A
G
E
---
A
V
L
S
-
G
L
V
N
S
L
G
A
L
I
S
F
L
---
S
S
G
S
T
-
G
T
Q
N
S
L
G
--
S
L
E
S
L
-----
N
S
E
G
A
A
R
F
N
----
A
K
--
Y
P
----
Q
G
I
P
T
S
A
C
G
E
G
A
Y
K
V
N
G
V
S
Y
Y
----
S
-
W
S
G
----
S
S
P
L
T
N
F
L
---
D
P
S
D
A
F
L
G
A
S
S
L
T
FKNG
T
A
N
D
G
L
V
G
T
CS
S
H
L
G
----
M
V
I
R
D
---------------------------
N
Y
R
M
N
H
L
D
E
V
N
--
Q
V
F
G
L
T
S
L
F
E
T
S
P
V
S
-
V
Y
R
Q
H
A
N
R
L
K
N
A
S
L
----------------------