@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLP7: (2017-11-03 )
MNFKPLAYILLATSSLTACTMAPVKEQKIEPFVFKEPELTPPFYALNPFNYDAPPAFEVALKEAAAQPVTKMVVTRQDDPTKTLTLDTNKLIVPTVNNSQRSMKYAVLAGDNEIDVTEIDDFLQLVEGKARHYPPRFTDRQERKGFESKLMEVTQRLDTLAANPDASFDILIRAFKASVLARNLDLGTAHTTKSLEYAQRLLKINPDDAEANFWFGFGLSEGGGQREAIPYLDKAIKGNVQEAYLAAANNYIAMEQKKNAIQTLKNYKVKYPDEAEVADRLIQEIEKQGRWNVWQVLTNPAMSSATPSAATKK
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------.........10........20..------......30........40.-----.......50.-......----.60.--..-....---------.70........80........90........100.......110.......120--.--------......-..130------------......------..140-------.........150--..----....-.160-.-------......170.......------------------180..---.....190--..-----......200.....--------..210..----------.....220.......-----------230.....-----.-----------.-240........250.......260.......270-----------..-----..-------...280..--.....-----290.......300.......310.------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------MNFK
P
L
A
Y
I
L
L
ATSSL
T
A
CTMAP------VKEQKIE
P
F
V
FKEPELTPP-----
F
Y
A
LNPFNYD-AP
P
A
F
E
----
V
A
L
K
--
E
A-AAQ
P
---------
V
T
K
M
V
V
TRQDDPT
K
T
L
T
LDTN
K
L
I
V
PTVNNSQ
R
S
M
K
Y
A
V
L
AGDNEI
D
V
T
E
I
D
----
D
--------
F
L
Q
L
V
E-GKAR-------------HYPPRF------T
D
R
---------
Q
E
RK
G
F
E
S
K
L
M
E
--
V
T
----
Q
R
L
D
-
T
LAA-N-------PD
A
S
F
D
I
L
I
R
A
F
K
A
S
V
------------------
L
ARNL---DLGTAHT---T
K
-----
S
L
E
Y
A
Q
R
L
LKINPD--------DAEA
N
F
W
----------
F
G
FGLSEGGGQR
E
A
I
-----------
P
Y
L
D
K
A
IK-----G-----------
N
-
V
Q
-
E
A
Y
L
A
AAN
N
Y
I
A
M
E
Q
K
K
N
A
I
Q
T
L
K
NYKVKYP-----------
D
E
-----
A
E
-------
V
A
D
R
L
I
Q
E
--
I
E
KQG-----RWN
V
W
Q
V
LTNPAMSSATPSAATKK------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
61.54
18%
-
- C5 -
-
5DSE
-
TTC7B_HUMAN
A:
[140-843]
V
I
A
E
A
Y
A
T
K
G
L
C
L
ED
V
I
T
C
Y
E
K
A
G
D
I
A
L
L
Y
L
Q
E
I
E
R
VLG
F
F
L
E
T
G
L
Q
R
A
H
V
L
Y
F
K
N
GN
L
T
R
G
V
G
R
F
R
E
L
L
R
AVETRTT
Q
N
L
R
M
T
I
A
R
Q
L
A
E
I
L
L
RGMCEQSYWNPLEDPFCPQE
N
T
E
E
A
L
L
L
L
L
I
S
E
S
M
A
N
R
S
V
V
Y
D
L
L
T
I
A
L
G
R
R
G
Q
Y
E
M
------
L
S
E
C
L
E
R
A
M
K
F
A
F
E
E
------------
F
H
L
W
Y
Q
F
-
A
L
S
L
M
A
----
A
G
K
S
--
A
R
-
A
V
K
V
---------
L
K
E
C
I
R
L
K
P
D
D
A
--
T
I
P
L
L
A
A
K
L
C
M
G
S
L
H
W
L
E
E
A
E
K
F
A
K
T
V
V
T
S
E
F
K
A
-
K
G
Y
----
L
--------
A
L
G
L
T
Y
-
S
L
Q
A
-------------
T
D
A
S
L
---------
R
---------
G
M
Q
E
V
L
Q
R
K
A
L
L
--
A
F
----
Q
R
A
H
-
S
L
S
P
T
D
-------
H
Q
A
A
F
Y
L
A
L
Q
L
A
I
S
R
--------------------------------
Q
I
---
P
E
-----
A
L
G
Y
V
R
Q
A
L
Q
L
Q
G
D
--------
D
A
N
S
L
H
L
----------
L
A
L
L
L
S
A
Q
K
H
Y
H
D
A
L
-----------
N
I
I
D
M
A
L
S
-----
E
-----------
Y
----------
P
E
N
F
I
L
L
F
S
K
V
K
L
Q
S
L
C
R
G
-----
P
-----------
D
E
-----
A
L
-------
L
T
C
K
H
M
L
Q
--
I
W
K
S
C
-----
Y
L
H
P
W
M
T
L
A
Q
I
W
L
H
A
A
E
V
Y
I
G
I
G
K
P
A
E
A
T
A
C
T
Q
E
A
A
N
L
FPMS
H
N
V
L
Y
M
R
G
Q
I
A
E
L
R
GS
M
D
E
A
R
R
W
Y
E
E
A
L
A
I
SPTH
V
K
S
M
Q
R
L
A
L
I
L
H
Q
L
GR
Y
S
L
A
E
K
I
L
R
D
A
V
Q
V
NSTA
H
E
V
W
N
G
L
G
E
V
L
Q
A
Q
GN
D
A
A
A
T
E
C
F
L
T
A
L
E
L
E
A
S
SPAVPFTIIPRVL
37
HHSearch
59.73
16%
-59
- C5 -
-
2PL2
-
?
B:
[122-221]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
L
---
E
Q
-----
A
L
S
V
L
K
D
A
E
R
V
N
P
R
--------
Y
A
P
L
H
L
Q
----------
R
G
L
V
Y
A
L
L
G
E
R
D
K
A
E
-----------
A
S
L
K
Q
A
L
A
-----
L
-----------
E
D
T
P
-
E
I
R
S
A
L
A
E
L
Y
L
S
M
G
R
L
D
E
A
L
A
Q
Y
A
K
A
L
E
Q
A
P
-----------
K
D
-----
L
D
-------
L
R
V
R
Y
A
S
A
--
L
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
59.18
20%
34
- C2 -
-
4XB6
-
PHNI_ECOLI
C:
[1-353]
-------------------------------------------------------------------------------------------------------------------M
Y
V
A
V
K
G
G
E
K
A
I
D
A
A
H
A
L
Q
E
S
R
R
R
G
D
T
D
L
P
E
L
S
V
A
Q
------
I
E
Q
Q
L
N
L
A
V
D
R
V
M
T
E
G
G
I
A
D
R
E
L
A
A
L
A
L
K
Q
A
S
G
D
-
N
V
E
A
I
F
----
L
L
R
A
--
Y
R
-
T
T
L
A
KLAVSEPLD
T
T
G
M
R
L
E
R
R
I
S
A
V
Y
K
-
D
I
P
G
G
Q
L
L
G
P
T
Y
D
Y
T
H
R
L
L
D
F
T
L
L
A
N
G
E
A
P
T
L
T
T
A
D
----
S
EQQPSPH
V
F
S
L
L
A
R
Q
G
L
A
K
FEEDSG
A
Q
P
D
D
IT
R
T
P
P
V
Y
PCS
R
S
S
R
L
Q
---------
Q
L
M
R
G
D
E
G
Y
L
L
A
--
L
A
----
Y
S
T
Q
-
R
-
G
Y
-
G
-------
R
N
H
P
F
A
G
E
I
R
S
G
Y
I
D
V
------------------
S
I
V
P
E
---
E
L
G
F
A
V
N
VGE
L
L
-----
M
T
E
C
E
M
V
N
G
F
I
D
P
P
--------
G
E
P
P
H
F
T
----------
R
G
Y
G
L
V
F
G
M
S
E
R
K
A
M
A
M
A
L
V
D
R
A
L
QA
P
E
Y
G
E
H
A
T
-----
G
-----------
P
-
A
Q
D
E
E
F
V
L
A
H
A
D
N
V
E
V
A
G
F
V
S
H
L
K
L
--
P
H
Y
V
D
F
Q
-----------
A
E
-----
L
E
-------
L
L
K
R
L
Q
Q
E
--
Q
N
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
55.73
11%
18
- C5 -
-
1FCH
-
PEX5_HUMAN
A:
[46-368]
------------------------------------------------------------------------------------------------------------------------------------------------
S
A
T
Y
D
K
G
------
Y
Q
F
E
E
E
N
P
L
R
D
H
P
Q
P
F
E
E
G
-----
L
R
R
L
Q
E
G
D
L
P
N
A
V
L
L
F
E
----
A
A
V
Q
Q
D
P
K
-
H
M
E
A
---------
W
Q
Y
L
G
T
T
Q
A
E
N
E
Q
E
L
L
A
I
S
A
L
R
R
C
L
E
L
K
P
D
N
Q
T
A
L
M
A
L
A
V
S
F
T
N
E
S
L
Q
R
Q
A
C
----
E
--------
I
L
R
D
W
L
-
R
Y
T
P
-------------
A
Y
A
H
L
V
------
T
R
I
---------
L
G
S
L
L
S
D
S
L
F
L
E
--
V
K
----
E
L
F
L
-
A
A
V
R
-
L
-------
D
P
T
S
I
D
P
D
V
Q
C
G
L
G
V
L
------------------
F
N
L
--------
S
G
E
Y
---
D
K
-----
A
V
D
C
F
T
A
A
L
S
V
R
P
N
--------
D
Y
L
L
W
N
K
----------
L
G
A
T
L
A
N
G
N
Q
S
E
E
A
V
-----------
A
A
Y
R
R
A
L
E
L
Q---
P
-----------
G
-
Y
I
-
R
S
R
Y
N
L
G
I
S
C
I
N
L
G
A
H
R
E
A
V
E
H
F
L
E
A
L
N
M
Q
R
-----------
K
S
GGAMS
E
N
-------
I
W
S
T
L
R
L
A
--
L
S
M
L
G
-----
Q
S
D
A
Y
G
A
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
P
Q
------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
54.12
18%
9
- C5 -
-
3AS5
-
?
A:
[58-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
---
D
R
-----
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--------
N
V
K
V
A
T
V
----------
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
-----------
P
L
L
I
K
V
A
E
-----
A
N
P---------
I
-
N
F
-
N
V
R
F
R
L
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
P
-----------
N
E
-----
G
K
-------
V
H
R
A
I
A
F
S
--
Y
E
Q
M
G
-----
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
---------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
53.78
29%
65
- C5 -
-
5MGX
-
FKBP8_HUMAN
E:
[125-244]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
R
V
A
L
A
N
R
K
R
E
--
C
G
N
A
H
Y
Q
R
A
D
F
V
L
A
A
-
N
----------
S
Y
D
L
A
I
K
A
I
T
S
S
A
K
V
D
M
T
F
E
E
E
A
Q
L
L
Q
L
K
V
K
C
L
N
N
L
A
A
S
Q
L
K
L
D
H
Y
---
R
A
-----
A
L
R
S
C
S
L
V
L
E
H
Q
P
D
--------
N
I
K
A
L
F
R
----------
K
G
K
V
L
A
Q
Q
G
E
Y
S
E
A
I
-----------
P
I
L
R
A
A
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
53.73
18%
24
- C5 -
-
3VTX
1
?
B:
[55-170]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
---
N
D
-----
A
I
E
S
L
K
K
F
V
V
L
D
T
T
--------
S
A
E
A
Y
Y
I
----------
L
G
S
A
N
F
M
I
D
E
K
Q
A
A
I
-----------
D
A
L
Q
R
A
I
A
-----
L
NT---------
V
-
Y
A
-
D
A
Y
Y
K
L
G
L
V
Y
D
S
M
G
E
H
D
K
A
I
E
A
Y
E
K
T
I
S
I
K
P
-----------
G
F
-----
I
R
-------
A
Y
Q
S
I
G
L
A
--
Y
E
G
K
G
-----
L
R
D
E
A
V
K
Y
F
K
K
A
L
E
K
---------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
53.10
22%
45
- C5 -
-
4I17
1
?
A:
[22-146]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Y
---
A
V
-----
A
F
E
K
Y
S
E
Y
L
K
L
T
N
N
Q-------
D
S
V
T
A
Y
N
----------
C
G
V
C
A
D
N
I
K
K
Y
K
E
A
A
-----------
D
Y
F
D
I
A
I
K
-----
K
NY---------
N
-
L
A
-
N
A
Y
I
G
K
S
A
A
Y
R
D
M
K
N
N
Q
E
Y
I
A
T
L
T
E
G
I
K
A
V
P
-----------
G
N
-----
A
T
I
E
K
L
Y
A
I
Y
Y
L
K
E
G
Q
K
--
F
Q
Q
A
G
-----
N
I
E
K
A
E
E
N
Y
K
H
A
T
D
V
---------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
52.64
18%
11
* C5 *
-
3AS5
-
?
B:
[58-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
---
D
R
-----
G
T
E
L
L
E
R
S
L
A
D
A
P
D
--------
N
V
K
V
A
T
V
----------
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
-----------
P
L
L
I
K
V
A
E
-----
A
N
P---------
I
-
N
F
-
N
V
R
F
R
L
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
P
-----------
N
E
-----
G
K
-------
V
H
R
A
I
A
F
S
--
Y
E
Q
M
G
-----
R
H
E
E
A
L
P
H
F
K
K
A
N
E
L
---------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
52.28
20%
-16
- C5 -
-
4UI9
-
CDC23_HUMAN
C:
[342-463]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
-----
A
A
L
Y
F
Q
R
A
L
K
L
N
P
R
--------
Y
L
G
A
W
T
L
----------
M
G
H
E
Y
M
E
M
K
N
T
S
A
A
I
-----------
Q
A
Y
R
H
A
I
E
-----
V
NK---------
R
-
D
Y
-
R
A
W
Y
G
L
G
Q
T
Y
E
I
L
K
M
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
P
-----------
N
D
-----
S
R
-------
M
L
V
A
L
G
E
C
--
Y
E
K
L
N
-----
Q
L
V
E
A
K
K
C
Y
W
R
A
Y
A
----------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
51.29
16%
-12
- C5 -
-
2XEV
-
?
A:
[3-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
A
Y
N
V
A
------------------
F
D
A
L
K
---
N
G
K
Y
D
D
A
---
S
Q
-----
L
F
L
S
F
L
E
L
Y
P
N
G
V
Y
--------
T
P
N
A
L
Y
W
----------
L
G
E
S
Y
Y
A
T
R
N
F
Q
L
A
E
-----------
A
Q
F
R
D
L
V
S
R
YPTH
D
-----------
K
-
A
A
-
G
G
L
L
K
L
G
L
S
Q
Y
G
E
G
K
N
T
E
A
Q
Q
T
L
Q
Q
V
A
T
Q
Y
P
GS---------
D
A
-----
A
R
-------
V
A
Q
E
R
L
Q
S
--
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
51.24
16%
46
- C3 -
-
5F9S
2
SPYA_HUMAN
A:
[1-385]
--------------------------------------------------------------------------------------------------------------------------------
L
L
V
T
P
P
K
A
L
L
K
P
L
S
I
P
N
Q
L
L
L
G
P
GP
S
N
L
P
P
R
I
M
A
A
G
G
L
Q
M
I
G
S
M
S
K
D
M
-----
Y
Q
I
M
D
E
I
K
E
G
-
I
Q
Y
V
F
Q
TRNP
L
T
L
V
--
I
S
G
S
G
H
C
---------
A
L
E
A
A
L
V
N
V
L
E
P
G
D
S
F
L
V
G
A
N
G
------
I
W
G
Q
R
A
V
D
I
G
E
R
I
G
A
R
V
H
P
M
T
K
D
P
G
G
H
Y
T
--------
L
Q
E
V
E
E
-
G
L
A
Q
-------------
H
K
P
V
L
L
------
F
L
T
HGESSTG
V
L
Q
P
L
D
G
F
G
E
L
C
H
R
Y
K
C
L
----
L
L
V
D
-
S
V
A
S
-
L
GGTPLYM
D
R
Q
G
I
D
I
L
Y
S
G
---
S
Q
------------------
K
A
L
N
A
---
P
P
G
T
S
L
I
---
S
F
-----
S
D
K
A
K
K
K
M
Y
S
R
K
T
K
PFSFYLD
I
K
W
L
A
N
F
W
GCDDQPRMYH
H
T
I
P
V
I
S
L
Y
S
L
R
E
S
L
-----------
A
L
I
A
E
Q
G
L
-----
E
-----------
N
-
S
W
-
R
Q
H
R
E
A
A
A
Y
L
H
G
R
L
Q
A
L
G
L
Q
L
F
V
K
D
P
A
L
R
L
P
T
V
T
T
V
A
VPAGY
D
W
-----
R
D
-------
I
V
S
Y
V
I
D
H
FD
I
E
I
M
G
G
LGPS
T
G
K
V
L
R
I
G
L
L
G
C
N
A
T
R
E
N
V
D
R
V
T
E
A
L
R
A
A
L
Q
H
CPKK------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
50.83
29%
101
- C5 -
-
1NA0
-
?
A:
[13-125]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
N
L
G
N
A
Y
Y
---
K
Q
GD
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
--------
N
A
E
A
W
Y
N
----------
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
-----------
E
Y
Y
Q
K
A
L
E
L
D---
P
-----------
N
-
N
A
-
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
-----------
N
N
-----
A
E
-------
A
K
Q
N
L
G
N
A
--
K
Q
K
Q
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
49.16
23%
-80
- C5 -
-
4MYA
3
?
A:
[73-180]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
M
D
T
V
T
E
A
D
M
A
I
A
------------------
M
A
R
Q
G
---
G
L
G
I
I
H
K
---
N
M
-----
S
I
E
--
Q
Q
A
E
Q
V
D
K
V
--------
K
R
S
G
G
L
L
----------
V
G
A
A
V
---
G
V
T
A
D
A
M
-----------
T
R
I
D
A
L
V
K
-----
A
-----------
S
-
V
D
-
A
I
V
L
D
T
A
H
G
H
-----
S
Q
G
V
I
D
K
V
K
E
V
R
A
K
Y
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
48.72
30%
89
- C5 -
-
2WQH
4
?
A:
[13-108]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
N
L
G
N
A
Y
Y
---
K
Q
GD
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
Y
P
N
--------
N
A
E
A
W
Y
N
----------
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
-----------
E
Y
Y
Q
K
A
L
E
L
Y---
P
-----------
N
-
N
A
-
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
Y
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
48.71
13%
-26
- C5 -
-
3HYM
-
CDC16_HUMAN
H:
[176-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
-----
A
E
R
F
F
S
Q
A
L
S
I
A
P
E
--------
D
P
F
V
M
H
E
----------
V
G
V
V
A
F
Q
N
G
E
W
K
T
A
E
-----------
K
W
F
L
D
A
L
E
-----
K
IKAIGNEVTVD
K
-
W
E
-
P
L
L
N
N
L
G
H
V
C
R
K
L
K
K
Y
A
E
A
L
D
Y
H
R
Q
A
L
V
L
I
P
-----------
Q
N
-----
A
S
-------
T
Y
S
A
I
G
Y
I
--
H
S
L
M
G
-----
N
F
E
N
A
V
D
Y
F
H
T
A
L
G
----------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
48.36
16%
29
- C5 -
-
4R7S
3
?
A:
[90-206]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
---
E
K
-----
A
L
N
D
Y
N
T
L
L
I
E
N
P
E
--------
H
Q
E
A
L
Y
C
----------
R
G
L
L
Y
I
Q
L
Q
N
Y
M
W
A
E
-----------
Q
D
F
D
K
I
L
E
-----
V
N
E---------
K
-
S
V
-
R
A
R
L
G
H
A
I
L
E
K
M
R
G
N
Y
D
E
S
E
R
I
F
N
Y
L
I
S
E
M
P
-----------
R
D
-----
W
I
-------
L
Y
E
G
R
A
D
L
--
Y
F
M
M
G
-----
K
N
A
R
A
M
A
D
I
E
K
V
F
T
E
---------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
48.35
13%
2
- C5 -
-
2Q7F
-
YRRB_BACSU
B:
[108-222]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
K
E
-----
A
K
D
M
F
E
K
A
L
R
A
G
M
E
--------
N
G
D
L
F
Y
M
----------
L
G
T
V
L
V
K
L
E
Q
P
K
L
A
L
-----------
P
Y
L
Q
R
A
V
E
-----
L
NE---------
N
-
D
T
-
E
A
R
F
Q
F
G
M
C
L
A
N
E
G
M
L
D
E
A
L
S
Q
F
A
A
V
T
E
Q
D
P
-----------
G
H
-----
A
D
-------
A
F
Y
N
A
G
V
T
--
Y
A
Y
K
E
-----
N
R
E
K
A
L
E
M
L
D
K
A
I
D
----------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
48.27
23%
-82
- C5 -
-
4MY8
5
?
A:
[73-179]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
M
D
T
V
T
E
A
D
M
A
I
A
------------------
M
A
R
Q
G
---
G
L
G
I
I
H
K
---
N
M
-----
S
I
E
--
Q
Q
A
E
Q
V
D
K
V
--------
K
R
S
G
G
L
L
----------
V
G
A
A
V
---
G
V
T
A
D
A
M
-----------
T
R
I
D
A
L
V
K
-----
A
-----------
S
-
V
D
-
A
I
V
L
D
T
A
H
G
H
-----
S
Q
G
V
I
D
K
V
K
E
V
R
A
K
Y
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
48.00
23%
-77
- C5 -
-
4MYX
2
?
A:
[73-181]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
M
D
T
V
T
E
A
D
M
A
I
A
------------------
M
A
R
Q
G
---
G
L
G
I
I
H
K
---
N
M
-----
S
I
E
--
Q
Q
A
E
Q
V
D
K
V
--------
K
R
S
G
G
L
L
----------
V
G
A
A
V
---
G
V
T
A
D
A
M
-----------
T
R
I
D
A
L
V
K
-----
A
-----------
S
-
V
D
-
A
I
V
L
D
T
A
H
G
H
-----
S
Q
G
V
I
D
K
V
K
E
V
R
A
K
Y
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------