@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLT2: (2017-11-04 )
MNNTQWLDEVKFNEQGLIPAIAQHHQTGRILMVAWMNRESLALTAEKNQAVYFSRSRQKLWHKGEESGHFQTVYEIRLDCDGDVIVLQVEQHGGIACHTGRESCFYRKLTPQGWEIVDAQLKDPTAIYGDNAKTESHDHAHTNEQVDVLAHLGQLMQERKQAEADTSYVSSLYKKGINKILEKVGEEGVETIIAAKDYAAQNTESNLNDLIYETADLWFHSIVMLGYFDLNPQLIIDELGRRQGLSGLVEKANRNKV
Atome Classification :
(20 SA)
-----.........10...----.....20....-----------....30....-...-----.-40........50...-..---...60........70-......----...80.-..-.....90........100.......110.......120--.-......130.......140.......150....-...160...------------.....170....-...180....-...190-......--.200.......210..-...-------..220----.......230...-..-..-240.......250.-....-------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----MNN
T
Q
W
L
D
EVKFNE----QGL
I
P
A
I
A
Q
HH-----------QT
G
R
I
L
M
V
A
W
-MNR-----E-
S
L
A
L
T
AEKN
Q
A
V
Y
F
S
-
R
S
---
R
Q
K
L
WHKGEESG
H
F
--
Q
T
V
Y
E
I
----
R
LDCDG-
D
V
-
I
V
L
Q
V
EQHG
G
I
A
C
HTGRES
C
F
Y
RKLTPQG
W
E
I
V
D
AQLK--D-P
T
A
IYGDNAKTESHDHAH
T
N
E
Q
V
D
V
L
A
H
L
G
Q
L
M
-
Q
E
R
K
Q-AEA------------
D
T
S
Y
V
S
S
L
Y
K
K
G
-
I
N
K
I
L
E
K
V
G
E-E
G
V
E
T
I
-
I
A
AKDY--AAQNTES
N
L
N
D
L
I
Y
E
T
-
A
D
L
-------
W
F
H
S
I
----
V
M
L
GYFDL
N
P
Q
L
I
-
I
D
-
E
L
-GRRQ
G
L
S
G
L
V
E
KAN-RNKV-------------------------------------------------------------------------
1
PsiBlast_PDB
81.57
53%
-78
- C7 -
-
1ZPS
3
HIS3_METTH
A:
[18-131]
----------------
I
N
G
----
E
D
L
I
I
A
V
A
Q
D
H
-----------
E
T
G
E
V
L
M
V
A
Y
-
M
N
R
-----
E
-
A
L
R
R
T
L
E
T
G
T
A
H
Y
W
S
-
T
S
---
R
G
K
L
W
L
K
G
E
S
S
G
H
V
--
Q
R
V
K
D
V
----
L
V
D
C
D
G
-
D
A
-
V
V
L
K
V
E
Q
E
G
G
-
A
C
H
T
G
Y
R
S
C
F
Y
R
S
I
D
G
D
E
L
K
V
R
E
D
A
V
K
VF
D
-
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
80.73
56%
-110
- C7 -
-
1ZPS
3
HIS3_METTH
A:
[17-117]
---------------
N
I
N
G
----
E
D
L
I
I
A
V
A
Q
D
H
-----------
E
T
G
E
V
L
M
V
A
Y
-
M
N
R
-----
E
-
A
L
R
R
T
L
E
T
G
T
A
H
Y
W
S
-
T
S
---
R
G
K
L
W
L
K
G
E
S
S
G
H
V
--
Q
R
V
K
D
V
----
L
V
D
C
D
G
-
D
A
-
V
V
L
K
V
E
Q
E
-
G
G
A
C
H
T
G
Y
R
S
C
F
Y
R
S
I
D
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
80.29
53%
-77
- C7 -
-
1ZPS
4
HIS3_METTH
B:
[18-131]
----------------
I
N
G
----
E
D
L
I
I
A
V
A
Q
D
H
-----------
E
T
G
E
V
L
M
V
A
Y
-
M
N
R
-----
E
-
A
L
R
R
T
L
E
T
G
T
A
H
Y
W
S
-
T
S
---
R
G
K
L
W
L
K
G
E
S
S
G
H
V
--
Q
R
V
K
D
V
----
L
V
D
C
D
G
-
D
A
-
V
V
L
K
V
E
Q
E
G
G
-
A
C
H
T
G
Y
R
S
C
F
Y
R
S
I
D
G
D
E
L
K
V
R
E
D
A
V
K
VF
D
-
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
79.44
56%
-109
* C7 *
-
1ZPS
4
HIS3_METTH
B:
[17-117]
---------------
N
I
N
G
----
E
D
L
I
I
A
V
A
Q
D
H
-----------
E
T
G
E
V
L
M
V
A
Y
-
M
N
R
-----
E
-
A
L
R
R
T
L
E
T
G
T
A
H
Y
W
S
-
T
S
---
R
G
K
L
W
L
K
G
E
S
S
G
H
V
--
Q
R
V
K
D
V
----
L
V
D
C
D
G
-
D
A
-
V
V
L
K
V
E
Q
E
-
G
G
A
C
H
T
G
Y
R
S
C
F
Y
R
S
I
D
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
78.80
47%
-81
- C7 -
-
1ZPS
3
HIS3_METTH
A:
[8-131]
------
V
N
I
L
L
N
F
R
H
N
I
N
G
----
E
D
L
I
I
A
V
A
Q
D
H
-----------
E
T
G
E
V
L
M
V
A
Y
-
M
N
R
-----
E
-
A
L
R
R
T
L
E
T
G
T
A
H
Y
W
S
-
T
S
---
R
G
K
L
W
L
K
G
E
S
S
G
H
V
--
Q
R
V
K
D
V
----
L
V
D
C
D
G
-
D
A
-
V
V
L
K
V
E
Q
E
G
-
G
A
C
H
T
G
Y
R
S
C
F
Y
R
S
I
D
G
D
E
L
K
V
R
E
D
A
V
K
--
V
-
F
D
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.65
44%
-77
- C6 -
-
2A7W
-
HIS2_CHRVO
A:
[4-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
K
N
I
A
D
T
L
-
E
A
R
R
E
-
A
A
P
------------
Q
S
S
Y
V
A
S
L
F
H
K
G
-
E
D
A
I
L
K
K
V
A
E
-
E
A
A
E
T
L
-
M
A
S
K
D
--------
K
D
K
L
H
-
L
V
R
E
V
-
A
D
L
-------
W
F
H
T
M
----
V
L
L
T
Y
H
G
L
R
P
E
D
V
-
V
M
-
E
L
-
H
R
R
E
G
---------------------------------------------------------------------------------------
35
HHSearch
70.45
46%
-78
- C6 -
-
2A7W
-
HIS2_CHRVO
H:
[4-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
K
N
I
A
D
T
L
-
E
A
R
R
E
-
A
A
P
------------
Q
S
S
Y
V
A
S
L
F
H
K
G
-
E
D
A
I
L
K
K
V
A
E
-
E
A
A
E
T
L
-
M
A
S
K
D
K
---------
D
K
L
H
L
V
R
E
V
-
A
D
L
-------
W
F
H
T
M
----
V
L
L
T
Y
H
G
L
R
P
E
D
V
-
V
M
-
E
L
-
H
R
R
E
G
---------------------------------------------------------------------------------------
38
HHSearch
66.14
31%
-93
- C6 -
-
1YVW
-
HIS2_BACCR
D:
[4-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
K
L
L
Y
K
T
I
-
E
E
R
K
G
-
S
P
L
------------
P
E
S
Y
T
N
Y
L
F
S
K
G
-
E
D
K
I
L
K
K
I
G
E
-
E
C
A
E
V
I
-
I
A
C
K
N
N
---------
D
K
E
E
V
V
K
E
M
-
V
D
V
-------
F
Y
H
C
F
----
V
L
L
A
E
K
N
I
A
L
E
D
V
-
M
R
-
E
V
-
K
E
R
N
G
K
L
-------------------------------------------------------------------------------------
24
Fugue
65.34
31%
-68
- C6 -
-
1YVW
-
HIS2_BACCR
A:
[4-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
K
L
L
Y
K
T
I
-
E
E
R
K
G
-
S
P
L
------------
P
E
S
Y
T
N
Y
L
F
S
K
G
-
E
D
K
I
L
K
K
I
G
E
-
E
C
A
E
V
I
-
I
A
C
K
N
----------
N
D
K
E
E
V
V
K
E
M
V
D
V
-------
F
Y
H
C
F
----
V
L
L
A
E
K
N
I
A
L
E
D
V
M
R
E
-
V
K
-
E
R
N
G
K
L
--------------------------------------------------------------------------------------
25
Fugue
63.05
43%
-41
- C6 -
-
2A7W
-
HIS2_CHRVO
A:
[4-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
L
K
N
I
A
D
T
L
-
E
A
R
R
E
-
A
A
P
------------
Q
S
S
Y
V
A
S
L
F
H
K
G
-
E
D
A
I
L
K
K
V
A
E
-
E
A
A
E
T
L
M
A
S
----------
K
D
K
D
K
L
H
L
V
R
E
V
-
A
D
L
-------
W
F
H
-
T
M
---
V
L
L
T
Y
H
G
L
R
P
E
D
V
--
V
M
E
L
-
H
R
R
E
G
---------------------------------------------------------------------------------------
3
PsiBlast_PDB
58.89
30%
-77
- C6 -
-
1YVW
-
HIS2_BACCR
A:
[8-93]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
K
T
I
-
E
E
R
K
G
-
S
P
L
------------
P
E
S
Y
T
N
Y
L
F
S
K
G
-
E
D
K
I
L
K
K
I
G
E
-
E
C
A
E
V
I
-
I
A
C
K
N
N
--
D
K
E
E
V
V
K
E
-------
M
-
V
D
V
-------
F
Y
H
C
F
----
V
L
L
A
E
K
N
I
A
L
E
D
V
-
M
R
-
E
V
-
K
E
R
N
G
---------------------------------------------------------------------------------------
34
HHSearch
56.63
23%
-96
- C6 -
-
1YXB
-
HIS2_STRCO
D:
[4-91]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
F
E
E
L
F
T
E
L
-
Q
H
K
A
A
N----------------
T
S
R
T
A
E
L
V
D
K
G
-
V
H
A
I
G
K
K
V
V
E
-
E
A
A
E
V
W
-
M
A
A
E
Y
E
---------
G
K
D
A
A
A
E
E
I
-
S
Q
L
-------
L
Y
H
V
Q
----
V
M
M
V
A
R
G
I
S
L
D
D
V
-
Y
A
-
H
L
-
L
-------------------------------------------------------------------------------------------
37
HHSearch
52.79
19%
-83
- C6 -
-
3C90
-
HIS2_MYCTU
B:
[7-93]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
T
F
E
D
L
F
A
E
L
-
G
D
R
A
R
-
T
R
P
------------
A
D
S
T
T
V
A
A
L
D
G
G
-
V
H
A
L
G
K
K
L
L
E
-
E
A
G
E
V
W
-
L
A
A
E
H
E
---------
S
N
D
A
L
A
E
E
I
-
S
Q
L
-------
L
Y
W
T
Q
----
V
L
M
I
S
R
G
L
S
L
D
D
V
-
Y
R
-
K
L
---------------------------------------------------------------------------------------------
26
Fugue
51.67
22%
32
- C6 -
-
2PNN
1
TRPV1_RAT
A:
[11-258]
----L
Y
D
R
R
S
I
F
D
A
V
A
Q
S
N
CQEL
E
S
L
L
P
F
L
Q
R
S
K
KRLTDSEFKDP
E
T
G
K
T
C
L
L
K
A
M
L
N
L
HNGQN
D
-
T
I
A
L
L
L
D
V
A
R
K
---
T
-
D
S
---
L
K
Q
F
V
N
A
S
Y
T
D
S
Y
Y
KG
Q
T
A
L
H
I
----
A
I
E
R
R
N
M
T
L
-
V
T
L
L
V
E
N
--
G
A
D
V
Q
A
A
A
N
G
D
F
F
K
K
T
K
G
R
--------------
P
G
F
Y
F
G
E
L
----
P
L
S
L
A
A
C
T
N
Q
L
A
I
V
K
F
L
L
Q
-----
N
S
W
-
Q
P
A
------------
D
---
I
S
A
R
D
S
V
G
---------------
N
T
V
-
L
H
A
L
V
E
--
V
A
D
N
T
V
D
N
T
K
F
V
T
S
M
-------------
Y
N
E
I
----
L
I
L
G
A
-
K
L
H
P
T
L
K
-
L
E
-
E
I
-
T
N
R
K
G
L
T
P
L
A
L
A
A
S
-
S
G
K
I
G
V
L
A
Y
I
L
Q
R
E
I
H-------------------------------------------------------------
12
PsiBlast_PDB
49.66
25%
-52
- C- -
-
2GHB
-
?
A:
[12-86]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
K
Q
V
D
I
L
Q
K
L
G
E
E
F
-
K
A
K
Y
G
-
V
E
V
------------
E
V
Q
Y
V
N
--
F
Q
D
I
-
K
S
K
F
L
T
A
A
P
E
G
Q
G
A
D
I
I
-
V
G
A
H
D
W
--
V
G
E
L
A
V
N
G
L
I
E
P
I
P
N
F
-
S
D
L
--------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
46.76
23%
-156
- C6 -
-
2W48
-
SORC_KLEPN
A:
[4-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
D
I
R
L
I
V
K
I
A
Q
L
Y
-
Y
E
Q
D
M
-
T
Q
A
------------
Q
I
A
R
E
L
G
I
Y
R
T
T
-
I
S
R
L
L
K
R
G
R
E
-
Q
G
I
V
T
I
-
A
I
N
Y
D
Y
------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
44.45
17%
-66
- C6 -
-
2YXH
-
?
A:
[3-90]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
L
L
E
I
I
-
E
R
S
L
R
----------------
K
C
P
W
L
E
K
---
Q
S
-
I
E
T
L
L
E
A
L
A
S
-
E
I
E
E
V
A
-
E
A
V
K
K
N
---------
D
L
A
N
L
E
E
E
I
-
G
D
M
-------
I
Y
D
A
L
L
V
A
A
V
A
Q
R
D
Y
G
I
D
L
E
S
A
-
I
Q
-
K
V
-
V
E
K
I
S
H
R
-------------------------------------------------------------------------------------
29
Fugue
42.88
17%
55
- C4 -
-
3PNT
-
?
A:
[196-444]
------
E
R
D
L
F
E
K
K
F
K
E
I
K
----
D
K
W
V
T
D
K
Q
A
D
E
-----------
F
I
E
T
A
D
K
Y
A
D
-
K
A
V
-----
Q
M
S
----
A
V
A
S
R
A
E
Y
Y
R
M
Y
V
---
S
R
K
Y
Q
Y
K
K
E
F
V
E
K
L
--
K
Q
V
Y
K
E
S
G
A
S
H
V
T
S
K
K
-
D
L
M
L
A
F
D
D
A
K
R
K
S
T
I
---
G
R
Q
---------
E
N
G
L
F
V
T
S
F
A
E
--
D
M
A
L
-
L
F
T
D
Q
G
K
L
K
S
A
D
Q
I
E
N
I
K
G
V
D
S
----
G
K
Y
S
-
D
G
V
Y
Q
-
Y
E
Y
------------
D
S
E
L
T
K
N
I
D
K
L
G
Y
I
R
T
A
S
G
D
T
P
G
-
A
N
S
L
N
I
-
P
G
C
Q
T
W
--
S
G
K
H
I
E
N
S
E
S
E
L
I
F
P
S
-
I
S
V
KDLK
S
K
A
V
L
A
E
I
----
D
A
K
G
Y
F
E
I
I
D
P
T
I
-
I
A
-
P
N
-
G
D
H
K
K
V
T
G
R
F
K
I
K
K
M
Q
D
---------------------------------------------------------------------------
7
PsiBlast_PDB
42.67
36%
-89
- C8 -
-
1IRI
1
G6PI_HUMAN
A:
[183-229]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
V
S
N
I
D
G
T
H
-
I
A
K
T
L
A
Q
L
N
P
-
E
S
S
L
F
I
-
I
A
S
K
T
F
--
T
T
Q
E
T
I
T
N
A
-----
E
T
-
A
K
E
-------
W
F
-----------------------------------------------------------------------------------------------------------------------
31
Fugue
42.66
10%
28
- C2 -
-
4RAA
-
?
A:
[9-362]
TIISF
K
E
H
T
D
V
N
A
D
S
I
L
E
L
----
S
F
L
K
L
Q
T
K
D
S
C
-----------
L
V
K
N
V
G
L
I
R
E
-
L
N
N
-----
C
-
L
L
I
L
D
S
A
N
S
N
L
Y
V
F
N
-
K
S
GAF
V
N
Q
I
G
Q
K
G
S
G
P
G
E
Y
--
I
L
L
S
S
F
----
F
V
D
N
N
K
-
N
Y
-
I
A
A
I
D
I
A
Q
D
K
V
L
Y
Y
N
A
T
D
F
S
F
L
Y
E
R
R
L
P
F
S
T
S
C
C
L
Q
L
E
--
D
-
G
N
L
L
W
N
S
R
E
Y
T
D
S
K
L
S
D
F
Y
F
V
V
T
D
S
L
F
D
I
I
D
Y
K
M
N
K
E
F
K
-
S
G
Y
TTGPSQM
I
Y
K
V
G
T
N
V
F
A
Y
T
P
F
D
L
T
-
I
Y
R
V
G
T
S
E
I
V
-
P
A
H
S
F
S
-
F
E
G
T
D
I
PS
L
D
F
L
N
K
T
S
N
Q
G
N
S
N
Y
L
-
Y
D
L
-------
I
Q
S
D
Y
----
I
S
Y
Y
C
V
E
E
T
E
R
D
L
-
F
V
-
C
Y
M
K
N
K
E
K
Y
I
G
L
Y
D
K
N
T
-
D
R
T
Y
N
Y
P
I
K
I
F
Q
D
Q
L
KVGELNYFSIGSVDD
Y
H
V
A
P
L
D
V
L
S
L
K
D
M
A
G
N
GYVFD
D
K
L
S
E
L
L
T
I
SNEED
N
S
I
L
L
F
V
R
IKK