@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLT4: (2017-11-04 )
MKLESIQFKHIALFHDLKIQFQYDKQPITLILGEQATGKSMLLKHIYHALTWFPARLKDARTPGIVMPDQDISHSRLQSKIEVSIQIPPEFGQLPETTSTQQTETSLCSWKLFKTLNSSGVGISQVETQQLDQTITLYHQVTRKDPLQGLPLLAYYPSERFVNDINLLNKNLPGITQSISAYDISFIPFTTFARFFEWLREISDIENAQAAHVVQRIISKQSNSQDQEEILRQLQLELAGHPKQLPSPNLYALKSALKIIFPELEDFYLQYHPKLQPMAHYKGEVLAFQQLSNTTKTWIALVGDVVRRLCLLNPLSLDPCLEGEGVLLIDQIDSQLDAAHCSEILNRLHRAFPRLQIIVTGSREELLEHAAAYQCFKLKHGKISPLDLNTTQQQLEHLYTLLQRDEALTPHMDPLPLDTEPATAQIDSLYQQIQNLNEQQKNELLRMIHAGDTSEETSSL
Atome Classification :
(20 SA)
--.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240-........250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350-.-......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--MKLE
S
I
Q
F
K
H
I
A
L
F
H
D
L
K
I
Q
F
Q
YDKQ
P
I
T
L
I
L
GEQAT
G
K
S
M
L
L
K
H
I
Y
H
A
L
T
W
F
P
A
R
LKDARTPGIVMPDQDI
S
H
S
R
L
QS
K
I
E
V
S
I
Q
IPPEFGQLPETTSTQQTETSLC
S
W
K
L
F
K
T
LNSSGVGI
S
Q
V
E
T
Q
Q
L
D
Q
T
I
T
L
Y
H
Q
V
TRKDPLQG
L
P
L
L
A
YYP
S
E
R
F
V
N
D
I
N
L
L
NKNLPGITQSISA
Y
D
I
S
F
I
P
F
T
T
F
A
R
F
F
E
W
L
R
E
I
S
D
IEN
A
Q
A
A
H
V
V
Q
R
I
I
S
KQSNS
Q
D
Q
E
E
I
L
R
Q
L
Q
L
E
LAGH--PKQLPS
P
N
L
Y
A
L
K
S
A
L
K
I
I
F
P
E
L
E
D
F
Y
L
Q
YHPKLQ
P
M
A
HYKG
E
V
L
A
F
Q
Q
LSN
T
T
K
T
W
I
A
L
V
G
D
V
V
R
R
L
CLLNPLSLDPCLEGE
G
V
L
L
I
D
Q
IDSQL
D
A
A
H
C
S
E
I
L
N
R
L
H
R
AF-
P
-
R
L
Q
I
I
V
TG
S
R
E
E
L
L
E
H
A
A
A
Y
Q
C
F
KLKHGKISPLDLN
T
T
Q
Q
Q
L
E
H
L
Y
T
L
L
QRDEALTPHMDPLPLDTEPA
T
A
Q
I
D
S
L
Y
Q
Q
I
Q
NL
N
E
Q
Q
K
N
E
L
L
R
M
IHAGDTSEETSSL
14
PsiBlast_PDB
55.61
33%
-233
- C2 -
-
4PL0
2
MCJD_ECOLX
A:
[500-556]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
I
I
I
D
E
A
T
S
A
L
D
Y
I
N
E
S
E
I
L
S
S
I
R
T
H
F
-
P
-
D
A
L
I
I
N
I
S
H
R
I
N
L
L
E
C
S
D
C
--
V
Y
V
L
N
E
G
N
I
-----------------------------------------------------------------------------
15
PsiBlast_PDB
54.69
33%
-232
- C2 -
-
5EG1
2
MCJD_ECOLX
A:
[500-556]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
I
I
I
D
E
A
T
S
A
L
D
Y
I
N
E
S
E
I
L
S
S
I
R
T
H
F
-
P
-
D
A
L
I
I
N
I
S
H
R
I
N
L
L
E
C
S
D
C
--
V
Y
V
L
N
E
G
N
I
-----------------------------------------------------------------------------
62
HHSearch
53.49
24%
-195
- C2 -
-
3GD7
-
CFTR_HUMAN (first)
B:
[154-235]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
V
L
S
H
G
H
K
Q
L
M
C
L
----
A
R
S
V
L
-----------
S
K
A
K
I
L
L
L
D
E
P
S
A
H
L
D
P
V
T
Y
Q
I
I
R
R
T
L
K
Q
A
F
-
A
-
D
C
T
V
I
L
C
E
A
R
I
E
A
M
L
E
C
D
--
Q
F
L
V
I
E
E
N
K
V
R
Q
Y
D
-------------------------------------------------------------------------
33
Fugue
52.80
14%
27
- C2 -
-
2O5V
-
RECF_DEIRA
A:
[2-359]
GD
V
R
L
S
A
L
S
T
L
N
Y
R
N
L
A
P
G
T
L
N
F
P
---
E
G
V
T
G
I
Y
G
E
N
G
A
G
K
T
N
L
L
E
A
A
Y
L
A
L
T
G
Q
T
D
A
P
R
I
E
Q
L
---------
I
Q
A
G
E
T
E
A
Y
V
R
A
D
L
Q
Q
G
G
S
L
S
I
Q
E
V
G
L
G
R
G
R
R
Q
L
K
V
D
G
V
R
A
R
T
G
D
------
L
P
R
G
G
A
V
W
I
R
P
E
D
S
E
L
V
F
G
P
P
S
G
R
R
A
Y
L
D
S
L
L
S
R
L
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
G
E
E
W
A
M
H
-
V
W
D
D
V
L
L
K
L
G
T
E
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
Q
L
G
S
R
K
T
L
A
L
T
L
T
E
S
T
S
P
E
T
Y
A
A
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
D
L
L
L
T
L
-----------
G
D
F
P
A
S
D
Y
A
S
R
G
E
G
R
T
V
A
L
A
L
R
R
A
E
L
E
L
L
R
E
K
F
G
E
D
P
------
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
-----
V
P
Q
A
I
V
T
G
T
E
L
A
P
G
A
A
----
L
T
L
R
A
Q
A
G
R
F
T
P
V
A
-------------------------------------------------------------
D
E
E
M
Q
A
E
G
T
A
--
63
HHSearch
52.56
24%
-200
- C2 -
-
3GD7
-
CFTR_HUMAN (first)
A:
[154-235]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
V
L
S
H
G
H
K
Q
L
M
C
L
----
A
R
S
V
L
-----------
S
K
A
K
I
L
L
L
D
E
P
S
A
H
L
D
P
V
T
Y
Q
I
I
R
R
T
L
K
Q
A
F
-
A
-
D
C
T
V
I
L
C
E
A
R
I
E
A
M
L
E
C
D
--
Q
F
L
V
I
E
E
N
K
V
R
Q
Y
D
-------------------------------------------------------------------------
24
PsiBlast_CBE
51.57
39%
-184
- C1 -
-
4NCJ
1
?
B:
[1-85]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
51.49
19%
-141
- C2 -
-
5H68
2
?
B:
[235-319]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
Q
H
L
S
L
L
S
G
G
E
R
A
L
T
A
I
A
L
L
F
S
I
L
K
-----------
V
R
P
V
P
F
C
V
L
D
Q
V
E
A
A
L
D
E
A
N
V
Q
R
Y
A
Q
Y
L
K
R
F
S
-
R
-
D
T
Q
F
I
V
I
T
H
R
K
G
T
M
E
E
A
D
--
V
L
Y
G
V
T
M
Q
-------------------------------------------------------------------------------
25
PsiBlast_CBE
51.16
39%
-183
* C1 *
-
3QKT
1
?
D:
[1-78]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.11
39%
-160
- C1 -
-
1F2T
-
RAD50_PYRFU
A:
[1-61]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.80
39%
-154
- C1 -
-
4NCH
-
RAD50_PYRFU
A:
[1-95]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
50.69
17%
-170
- C2 -
-
3QKU
1
?
A:
[257-350]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
W
E
G
K
E
R
P
L
T
F
L
S
G
G
E
R
I
A
L
G
L
A
F
R
L
A
M
S
L
Y
---------
L
A
G
E
I
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
R
Y
L
-
K
K
I
P
Q
V
I
L
V
S
H
D
E
E
L
K
D
A
A
D
H
--
V
I
R
I
S
L
E
N
------------------------------------------------------------------------------
1
PsiBlast_PDB
50.65
39%
-163
- C1 -
-
4NCK
-
?
A:
[1-83]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
50.04
39%
-185
- C1 -
-
4NCJ
1
?
C:
[1-76]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
49.60
39%
-179
- C1 -
-
1F2U
1
?
A:
[1-57]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
49.45
39%
-169
- C1 -
-
1F2U
1
?
C:
[1-57]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
49.15
18%
-166
* C2 *
-
3PIH
1
UVRA_THEMA
A:
[799-882]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
Q
P
A
T
T
L
S
G
G
E
A
Q
R
I
K
L
A
S
E
L
R
K
R
D
------------
T
G
R
T
L
Y
I
L
D
E
P
T
V
G
L
H
F
E
D
V
R
K
L
V
E
V
L
H
R
L
V
D
R
-
G
N
T
V
I
V
I
E
H
N
L
D
V
I
K
N
A
D
--
H
I
I
D
L
G
P
--------------------------------------------------------------------------------
46
HHSearch
48.66
19%
-136
- C2 -
-
5H68
2
?
A:
[235-319]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
Q
H
L
S
L
L
S
G
G
E
R
A
L
T
A
I
A
L
L
F
S
I
L
K
-----------
V
R
P
V
P
F
C
V
L
D
Q
V
E
A
A
L
D
E
A
N
V
Q
R
Y
A
Q
Y
L
K
R
F
S
-
R
-
D
T
Q
F
I
V
I
T
H
R
K
G
T
M
E
E
A
D
--
V
L
Y
G
V
T
M
Q
-------------------------------------------------------------------------------
22
PsiBlast_CBE
48.65
39%
-182
- C1 -
-
4NCJ
1
?
D:
[1-75]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
48.63
39%
-171
- C1 -
-
4NCJ
1
RAD50_PYRFU
A:
[1-85]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.60
39%
-174
- C1 -
-
3QKR
-
?
A:
[1-57]
--
M
K
L
E
R
V
T
V
K
N
F
R
S
H
S
D
T
V
V
E
F
---
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
L
V
G
L
Y
W
-
P
L
R
I
K
D
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------