@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLT8: (2017-11-04 )
MQLSKLLDHWFPHPFVSFLIIIFWLMLAHSLDASDLLMAVILGLVIPRLVRPFITRTPHIHWKPAIKLCFVVLWDIIISNFRVAKLVLGPPKKLHPKWYRVPLETEHEQVNSLLAMIITTTPGTVSAGIDQERGDILVHSLSTENTESDVQDIKQRYEAPLIEIFDVKSKSEDNA
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.--.......20------......-----...30........40----------------........50...----------.....60-.-----...--------....----70..-----..--....80.......------.90........----100....---...110.........120.......130.......----.140.-......150.....------..-.160......-..170...---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
Q
L
S
K
L
L
D
H
WFP--
H
P
F
V
S
F
L
I
-------
I
I
F
W
L
M
-----
L
AHSL
D
A
S
D
L
L
M
A
V
I
----------------
L
G
L
V
I
P
R
L
V
R
P
F
I----------TRTP
H
I
H
-
W
-----
K
P
A
--------
I
K
L
C
----
F
V
V
L
-----
W
D
--
I
I
ISN
F
R
V
A
K
L
VL------GPPKKLHP
K
W
Y
----RVPLE
T
E
---
H
E
Q
V
--
N
S
L
L
A
M
I
I
TTTPGTVSAGIDQ-ERG
D
I
L
V
----
H
SLST-ENT
E
S
D
V
-
Q
D
I
K
Q
R
------YE-AP-
L
I
E
I
F
DV-KSKSEDNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
76.84
21%
-
- C3 -
-
4C0E
-
?
A:
[1674-2193]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
E
A
A
H
L
L
E
Q
M
E
Y
V
F
D
E
W
I
H
L
C
N
NPHAT
E
R
A
A
M
I
F
V
H
Q
L
H
S
V
QLVTN
R
D
E
F
L
L
F
L
R
H
A
L
D
K
S
V
E
R
F
E
Q
G
I
H
S
GAS
I
A
E
S
F
Q
A
V
E
A
L
V
K
L
I
I
I
F
V
K
SHS
A
A
V
A
F
M
D
S
I
L
A
L
G
V
L
V
A
N
S
H
H
V
K
RGENFN
Q
R
V
F
Y
R
F
F
A
L
L
L
H
E
V
G
L
L
A
GHFS
K
S
H
Y
E
Q
I
I
L
N
F
A
A
R
L
F
D
M
RPNLLPGF
A
C
A
W
A
G
L
V
S
H
--------
R
A
F
L
P
-------
V
I
L
G
L
P
-----
D
E
K
G
W
A
P
F
T
K
L
L
E
Q
F
----------------
L
G
C
V
-
G
E
L
V
K
T
F
T
----------
V
S
S
L
G
K
E
M
Y
-----
H
A
A
--------
L
K
I
L
----
I
V
L
Q
-----
H
D
F
P
I
Y
L
D
K
F
R
V
-
Q
L
C
Q
------
S
L
P
--
L
H
A
-----------------------
T
Q
L
V
N
L
I
L
A
A
I
P
P
N
C
N
S
L
A
D
P
-
F
Q
A
G
L
K
V
----
D
K
I
P
D
M
K
E
R
P
P
T
A
-
F
D
S
A
G
L
------
L
R
-
E
A
G
L
L
D
I
L
E
R
M
L
Q
N
G
P
S
E
D
G
V
A
Q
I
N
H
A
I
N
KSTSFGYVPLGVN
R
R
L
I
D
A
V
V
A
R
F
A
E
F
A
I
N
R
A
S
S
RSDSAIFVAGA
N
D
I
K
T
L
Q
M
L
V
T
E
VS
P
E
A
R
Y
Y
L
V
S
S
M
V
N
E
LRYPN
A
Y
T
N
Y
F
S
Q
A
L
L
D
I
F
G
HDMSD
P
E
E
N
L
V
R
E
Q
I
V
R
V
L
L
E
R
V
LGYWPQP
W
G
L
I
I
T
I
L
E
L
L
K
NDKYLFFEL
P
F
I
K
A
T
P
E
V
A
E
R
F
T
A
L
A
R
S
AA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
64.01
16%
-
- C- -
-
4ERN
-
ERCC3_HUMAN
A:
[502-730]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
K
V
Q
C
A
E
V
W
C
P
M
S
P
E
F
Y
R
E
Y
V
A
IKTK
K
R
I
L
L
Y
T
M
-----
N
P
N
K
F
R
A
C
Q
F
L
I
K
F
H
E
R
R
N
D
K
I
I
V
F
A
DN
V
F
A
L
K
E
Y
A
I
R
L
N
K
P
Y
I
Y
GPTS
Q
G
E
R
M
Q
I
L
Q
N
F
K
-
H
-----
N
P
K
--------
I
N
T
I
----
F
I
S
K
-----
V
G
--
D
T
S
F
D
L
P
E
A
N
V
L
I
Q
ISSHG
G
S
R
R
Q
E
A
Q
R
L
G
----
R
V
L
R
A
K
K
GMV
A
E
E
Y
--
N
A
F
F
Y
S
L
V
S
--
Q
D
T
Q
E
M
A
Y
S
T
-
K
R
Q
R
F
L
V
----
D
Q
G
Y
S
-
F
K
V
I
T
K
L
-
A
G
M
E
E
E
DLAFST
K
E
-
E
Q
-
Q
Q
L
L
Q
K
V
-
L
A
A
T
D
L
D
A
EEEVVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
59.26
16%
-118
- C3 -
-
1FEH
2
PHF1_CLOPA
A:
[1-126]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
T
I
-------
I
I
N
G
V
Q
-----
F
N
T
D
E
D
T
T
I
L
K
F
A
R
D
----------------
N
N
I
D
I
S
A
L
C
F
-----------------
L
N
N
-
C
-----
N
N
D
--------
I
N
K
C
----
E
I
C
T
-----
V
E
--
V
E
G
T
G
L
V
T
A
C
D
T
L
------
I
E
D
G
--------------------------------
M
I
I
N
T
N
----
S
D
A
V
N
E
-
K
I
K
S
R
I
S
----
Q
L
L
D
I
-
H
E
F
K
C
G
P
-
C
N
R
R
E
N
------
C
E
F
L
K
-
L
V
I
K
Y
K
A
-
R
A
S
K
P
F
L
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
56.96
26%
-81
- C3 -
-
2YCJ
2
?
A:
[74-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
V
--
V
D
L
P
C
C
L
D
S
T
N
P
D
A
I
E
A
G
L
K
V
-
H
R
G
H
A
M
I
----
N
S
T
S
A
-
D
Q
W
K
M
D
I
F
F
P
M
A
K
K
------
Y
E
-
A
A
-
I
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
56.82
26%
-79
- C3 -
-
2YCK
2
?
X:
[75-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
V
--
V
D
L
P
C
C
L
D
S
T
N
P
D
A
I
E
A
G
L
K
V
-
H
R
G
H
A
M
I
----
N
S
T
S
A
-
D
Q
W
K
M
D
I
F
F
P
M
A
K
K
------
Y
E
-
A
A
-
I
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
56.30
26%
-81
- C3 -
-
2YCI
-
?
X:
[74-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
V
--
V
D
L
P
C
C
L
D
S
T
N
P
D
A
I
E
A
G
L
K
V
-
H
R
G
H
A
M
I
----
N
S
T
S
A
-
D
Q
W
K
M
D
I
F
F
P
M
A
K
K
------
Y
E
-
A
A
-
I
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
54.48
19%
-42
- C2 -
-
5TVZ
-
A:
[4-106]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
K
P
S
A
----------
S
L
K
L
H
H
D
-
L
-----
K
L
C
LG
D
H
S
S
V
P
V
A
L
K
GQGP
F
T
L
T
-----
Y
D
--
I
I
E
T
F
S
S
K
R
K
T
F
E
------
I
K
E
I
K
T
N
E
Y
V
I
----
K
T
P
V
F
T
T
---
G
G
----
D
Y
I
L
S
L
V
S
I
K
D
S
T
G
C
V
V
G
L
S
Q
-
P
D
A
K
I
Q
V
----
R
R
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
50.85
34%
-195
- C3 -
-
3EH4
-
COX1_THET8
A:
[236-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
50.46
34%
-204
- C3 -
-
3BVD
3
COX1_THET8
A:
[186-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
50.31
34%
-216
- C3 -
-
2QPE
-
COX1_THET8
A:
[186-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
50.07
34%
-195
- C3 -
-
3EH5
-
COX1_THET8
A:
[236-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
48.00
29%
2
- C4 -
-
1E3H
-
PNP_STRAT
A:
[184-270]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
W
V
----
A
F
P
T
H
T
E
---
L
E
D
------------
A
V
F
D
M
V
V
A
G
R
V
L
-
E
D
G
D
V
A
I
----
M
M
V
E
A
-
E
A
T
E
K
T
I
-
Q
L
V
K
D
G
------
A
E
-
A
P
-
T
E
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
47.98
34%
-159
- C3 -
-
2QPD
-
COX1_THET8
A:
[186-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
46.91
27%
-24
- C5 -
-
3DOH
-
?
A:
[36-94]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
L
S
P
D
Q
F
----
S
V
K
V
K
T
G
---
D
T
Y
S
--
S
R
T
I
T
K
V
Y
A
N
N
S
G
G
L
S
F
S
I
F
N
-
N
R
G
K
Y
V
V
----
L
E
L
S
T
-
E
D
L
H
S
N
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.88
29%
-59
- C4 -
-
1E3P
-
PNP_STRAT
A:
[184-311]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
W
V
----
A
F
P
T
H
T
E
---
L
E
----
D
A
V
F
D
M
V
V
--------
A
G
R
V
L
-
E
D
G
D
V
A
I
----
M
M
V
E
A
-
E
A
T
E
K
T
I
-
Q
L
V
K
D
G
------
A
E
-
A
P
-
T
E
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
46.84
27%
-21
- C5 -
-
3DOI
-
?
A:
[36-94]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
L
S
P
D
Q
F
----
S
V
K
V
K
T
G
---
D
T
Y
S
--
S
R
T
I
T
K
V
Y
A
N
N
S
G
G
L
S
F
S
I
F
N
-
N
R
G
K
Y
V
V
----
L
E
L
S
T
-
E
D
L
H
S
N
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
46.72
18%
191
- C3 -
-
1Q0V
-
VPS27_YEAST
A:
[249-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
R
D
Y
----
S
T
P
-
E
D
E
---
E
E
L
I
--
R
K
A
I
E
L
S
L
K
E
S
R
N
S
A
S
S
E
P
I
V
-
P
V
V
E
S
K
N
----
E
V
K
R
Q
-
E
I
E
E
E
E
D
-
P
D
L
K
A
A
------
I
Q
-
E
S
-
L
R
E
A
E
E
A
-
K
L
R
S
E
R
Q
K
A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.84
23%
-
- C3 -
-
3S4W
-
FACD2_MOUSE
B:
[338-564]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
C
----
I
V
L
V
-----
F
D
--
V
I
K
S
A
I
R
Y
E
K
T
I
-------------
S
E
A
W
F
K
A
I
E
R
I
E
S
A
A
E
---
H
K
S
L
--
D
V
V
M
L
L
I
I
Y
S
T
S
T
Q
T
K
K
G
V
E
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
44.83
34%
-120
- C3 -
-
4G71
3
COX1_THET8
A:
[187-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
T
Y
M
A
-------
V
V
F
W
L
M
W
F
L
A
S
L
G
L
V
L
E
A
V
L
F
L
L
P
W
S
----------------
F
G
L
V
--
E
G
V
D
P
L
V
----------
A
R
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
44.64
14%
-15
- C3 -
-
2PO4
-
RPOLV_BPN4
A:
[11-1104]
G
I
D
A
V
Y
PSLVGTADSKAEGIKN
Y
F
K
L
S
F
TLPEEQKSRTVGSEA
P
L
K
D
V
A
Q
A
L
SS
R
A
R
Y
E
L
F
T
EKETANPAFN
G
E
V
I
K
R
Y
K
E
L
M
E
H
G
E
G
I
A
D
I
L
R
S
R
L
A
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L
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TKD
V
G
K
R
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GTEANRWVGGKLLNI
V
E
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GD
T
F
K
Y
N
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L
L
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A
V
L
A
G
L
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W
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L
TATSNTAIKD
A
K
D
V
A
A
I
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GIDQALLP
E
G
L
V
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F
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MT
L
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L
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GLSRNPNAPLGYT
K
G
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A
M
A
A
E
I
L
A
A
F
V
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TD
V
V
E
N
I
V
D
MSEIDPDNK
K
T
I
G
L
Y
T
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TELDSFD
P
I
N
S
F
PT
A
I
E
E
A
V
L
V
NPT
E
K
M
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GDDIPPVANTQLRNPAVRNT
P
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A
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A
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H
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SEDIST
V
P
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RVG
R
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GKYNPQSA
K
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LP
T
K
A
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--
L
S
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N
N
--
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F
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F
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L
-------
G
L
A
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A
L
-----
D
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K
V
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T
M
T
R
E
V
M
S
D
E
----------------
L
T
K
L
L
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G
N
L
K
P
A
I
----------
D
M
M
V
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N
-
T
TGSLP
E
N
A
--------
V
D
V
L
----
N
T
A
L
GDRKS
F
V
--
A
L
M
A
L
M
E
Y
S
R
Y
L
V
------
A
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D
K
S
A
----
F
----
V
T
P
L
Y
V
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---
A
D
G
V
T
N
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M
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G
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GSPN
K
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-
H
R
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A
D
N
-
N
D
L
Y
Q
A
------
S
T
-
N
A
-
L
M
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L
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K
-
L
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N
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S
N
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L
L
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D
L
FLPDINLGENGALELKRGIAKN
P
L
T
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T
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GSG
A
R
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V
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DPNIS
A
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FGKQAAS
E
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L
L
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TGTGAKGKINPK
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DPTWKKGDFLT
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NNLAPMIETGSQTFYIA
G
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AEVANQVLATNLDDRMRVPMSIYAPAQAGVA
G
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G
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M
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MKGAPKNTLKIFD
G
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LND
I
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A
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K
A
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A
V
Y
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W
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GN
P
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VDFSKLS
P
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L
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A
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EYDQRENAT
V
D
D
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A
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L
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DQMAAVG
A
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P
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L
N
K
L
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L
E
A
R
K
Q
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