@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLV7: (2017-11-04 )
MRIFTMKKTLSLPKAPIEMINRHKKINPAEMNKILNQHFNAFKQAAAQGDYVKAYQHVKKAVSLVPGHPGALSDLAYTELRLRRYDDAYQHYMQAIKASGSNVNTNLYDGLTEVCHHLNKKEEKIKFGRLAISTKKELTKNEPTLNIPTHKPVPFSPNPQENIIAFSLFGANPRYCETSILNTKLAQEIYPEWTCRFYVDESVPELVQQRLQANGAQVVHVSPTQKQLSGLFWRFLVMDDPVVKRFLVRDADSIVSYREKAAVDAWLKSDQWFHLMRDSYSHTELILVGMWGGCTGIFHNIEAHIRDYVATGRYPDNRVIDQHYLRYCIWPTLKQSVLVHDSQQFDENSADFPVYDLTSMQNDQDNFHVGMDNGSPVVTTAVNHPTAEKVYWILFDENHDEVCRYDAIVSKSRNIEVNLPHAFAKKIQLQQWKLQVYPYEN
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------.....--....10----------.........---------------20..-------------......30.......--.40......-..50........60......-.---.---------70.......---------.80---------------------...--------------.....90........100.--....-..110.......120..------------..-------------------...130.......140--------.........150-------------------------...-----......160.......170.......180---------........----.190-....--...200----------------------.--...-...210.--..--------..-..220.......230.--------------....--..240-...-----....-.250-----.....----...-------------------------260.......270..------....--.280.......290----......--..300....--------...310.......320----.........330.--....---..----340.......---350------.....----.-...360-.-......370---------.......380.......390------........400.......410.......---420-.......430--------.........440-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------
M
R
I
F
T
--
M
K
K
TL-----------SLPK
A
P
I
E
M
---------------
I
N
RH-------------KKI
N
P
A
E
M
N
K
I
L
N
Q
H
--
F
N
A
F
K
Q
A
AA-QG
D
Y
V
K
A
Y
Q
H
V
K
K
A
V
S
LVPG-H---P---------G
A
L
S
D
L
A
Y
T
---------
E
L
R
---------------------
L
R
R--------------Y
D
D
A
Y
Q
H
Y
M
Q
A
I
KASGSNV--N
T
N
L
-
Y
D
G
L
T
E
V
C
H
HLN
K
K
E
E
K
------------IK-------------------F
G
R
L
A
I
S
T
K
K
E
LTK----------NEPTLNIPTH---------------------------KPV-----PFSPNPQE
N
I
I
A
F
S
L
FGANP
R
Y
C
E
T
S
I
-----------
L
N
T
K
L
A
Q
E
----IYPE-
W
T
C
R
--
F
Y
VDE
S
----------------------
V
--
P
E
L
-
V
Q
Q
R
L
QA--NG--------
A
Q
-
V
V
H
VS
P
T
Q
K
Q
L
S
G
L
F
W
--------------
R
F
L
V--MD
D
P
--
V
V
K
-----
R
F
L
V-RD
A
------
D
S
I
V
S
----
Y
R
E
-------------------------
K
A
A
V
D
A
W
LKS
D
Q
W
F
H
------
L
M
R
D--SYSH
T
E
L
I
L
V
GMW-----G
G
C
T
G
I
--
F
H
N
I
E
A
H
I
R
--------
D
Y
V
ATGRYPDNR
V
I
------
D
Q
H
Y
L
R
Y
C
I
W
P
T
L
--
K
Q
S
V
---LV----HD
S
Q
QFDENS---A--------DFP
V
Y
----D-LTSMQN-D-QD
N
F
H
V
GMD---------NGS
P
V
V
T
T
AVNHPTA
E
K
V
Y
-------
W
I
L
F
DE
N
H
D
E
V
C
R
Y
D
A
I
VSKSR
N
I
E
V
NL---
P
H
A
-
F
A
K
K
I
Q
L
Q
----------
Q
W
K
L
Q
V
Y
PYEN------
45
Fugue
63.22
16%
20
* C5 *
-
4RIC
4
FAN1_HUMAN
A:
[1-631]
TGHP
Y
Y
L
R
S
F
L
V
V
L
K
T
V
L
E
N
E
D
D
M
L
L
F
D
E
Q
E
K
G
I
V
T
K
F
Y
Q
LS
A
T
G
Q
K
L
Y
V
R
L
F
Q
R
KL
S
W
I
K
MTKLEYEEIALDL
T
P
V
I
E
E
L
T
N
A
GFLQTESELQE
L
S
E
V
L
E
L
LS
A
P
E
L
K
S
L
A
K
T
F
H
--
L
V
N
P
N
-----------
G
Q
K
Q
Q
L
V
D
A
---------------
F
L
K
L
-------------
A
K
Q
R
S
V
I
G
A
V
I
L
K
R
A
--
K
A
L
A
G
Q
S
V
R
I
C
K
G
P
R
A
V
F
S
R
I
L
L
L
F
S
L
T
D
S
-
M
---
E
DEDAACGGQ
G
Q
L
S
T
V
L
L
V
---------
N
L
G
R
M
E
F
P
S
Y
T
I
N
R
K
T
HIFQD
R
D
D
L
I
R
--------------
Y
A
A
A
-
T
H
M
L
S
D
I
S
S
A
M
A
N
G
--
N
----
W
E
E
A
K
E
L
A
Q
C
A
K
R
D
W
N
R
------------
L
K
NH
P
S
L
R
C
H
E
D
LP
L
F
L
R
C
F
T
V
G
W
I
Y
T
R
I
L
S
R
F
V
E
----------
I
L
Q
R
L
H
M
--------------------------------
Y
-----
E
E
A
V
R
E
L
E
S
L
L
S
Q
R
I
Y
C
P
D
S
R
G
R
W
W
D
R
-----------
L
A
L
N
L
H
Q
H
----
L
K
R
L
-
E
P
T
I
--
K
C
I
T
E
G
----------------------
L
A
D
P
E
V
R
T
G
H
R
L
S
L
--
Y
Q
R
-------
A
V
-
R
L
R
E
S
P
S
C
K
K
F
K
H
L
F
Q
--------------
Q
L
P
E
--
M
A
V
Q
--
D
V
K
-----
H
V
T
I
-
T
G
R
L
CK
S
V
F
V
M
V
L
C
----
S
V
E
-------------------------
E
L
A
L
A
H
Y
R
R
S
G
F
D
Q
G
------
I
H
G
E
--
G
S
T
F
S
T
L
Y
G
L
L
L
W
DIIFM
D
G
I
P
D
V
--
F
R
N
A
C
Q
A
F
P
--------
L
D
L
C
T
D
S
F
F
T
S
R
R
P
------
A
L
E
A
R
L
Q
L
I
H
D
A
P
--
E
E
S
L
---
R
A
----
W
V
A
A
T
W
H
E
Q
E
GRV
A
--------
S
L
V
S
W
----
D
R
F
T
S
L
Q
Q
-
A
-
Q
D
L
V
S
C
L
------------
G
G
P
V
L
S
G
V
C
R
H
L
A
A
D
F
R
H
CRGGLPD
L
V
V
W
N
S
Q
S
R
---
H
F
K
L
V
E
V
K
G
P
N
D
R
L
S
H
---
K
Q
M
I
W
L
A
E
L
Q
K
L
----------
G
A
E
V
E
V
C
H
V
V
A
V-----
51
Fugue
62.24
17%
20
- C3 -
-
4TQT
6
?
A:
[14-490]
---------------------------------------------------------------------------------------------A
S
K
V
I
K
G
G
T
V
I
T
AD
R
T
F
R
A
D
I
L
I
--
E
D
G
K
I
-----------
A
A
I
G
D
S
L
E
G
D
E
V
I
D
ASG
C
Y
V
M
PG
G
I
D
P
H
-------------
T
H
L
Q
M
P
F
M
G
T
Y
S
S
D
D
--
F
D
T
G
T
A
A
A
L
-
A
G
G
T
T
M
V
V
D
F
V
------
L
P
D
-
S
---
E
---------
G
N
L
L
D
A
L
Q
E
---------
W
F
Q
---------------------
K
A
G
KAR
T
D
Y
S
F
H
M
A
I
TG
W
N
E
R
T
F
N
E
M
A
E
V
V
K
R
G
I
N
T
--
F
H
F
M
A
Y
K
G
A
L
M
V
----
N
D
D
E
M
F
------------
A
S
-------------------
F
Q
R
C
A
E
L
G
A
M
P
L
V
H
----------
A
E
N
G
D
I
V
A
Q
L
---------------------------
Q
A
K
-----
L
M
A
E
G
N
-
D
G
P
E
A
H
A
Y
S
R
P
P
E
V
E
G
E
A
T
N
-----------
R
A
I
M
I
A
D
Q
A
G
V
P
L
Y
V
V
-
H
V
S
C
--
E
Q
S
H
E
A
----------------------
I
--
R
R
A
-
R
Q
K
G
M
R
V
--
F
G
--------
E
P
L
I
Q
H
L
T
L
D
E
S
E
Y
H
N
R
D
W
--------------
D
Y
A
A
R
R
V
M
S
P
--
P
F
R
-----
D
K
L
---
N
Q
------
D
S
L
W
A
----
G
L
A
-------------------------
A
G
S
L
Q
C
V
A
T
D
H
C
A
F
T
------
T
E
Q
K
--
R
Y
G
I
G
N
F
T
K
I
P
-------
N
G
T
G
G
L
--
E
E
R
M
P
V
L
W
T
--------
R
G
V
R
T
G
R
L
T
P
N
E
F
V
------
A
V
T
S
T
N
I
A
K
I
L
N
I
YP
Q
K
G
A
---
V
V
----
P
G
A
D
---------
A
--------
D
L
V
I
W
----
D
-
P
E
T
T
K
K
I
S
-
A
K
T
Q
H
S
S
I
D
YNVFEG
F
E
L
K
G
L
P
I
M
T
L
S
R
G
---------------
R
I
A
F
D
K
G
-----
Q
V
T
A
K
P
G
D
G
R
F
I
E
--
R
---
E
P
N
-
G
A
V
N
R
A
L
S
----------
Q
W
K
E
I
V
A
P
R
K
V
E
R
S
A--
34
HHSearch
58.52
26%
-66
- C4 -
-
5FZQ
-
?
B:
[7-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
--
S
N
L
A
N
L
L
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
--
N
--
N
I
K
T
-
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
L
I
D
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
57.94
26%
-73
- C4 -
-
5FZS
-
?
A:
[6-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
L
--
S
N
L
A
N
L
L
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
--
N
--
N
I
K
T
-
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
L
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
57.77
27%
-76
- C4 -
-
5FZQ
-
?
C:
[7-104]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
--
S
N
L
A
N
L
L
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
--
N
--
N
I
K
T
-
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
L
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
57.70
26%
-70
- C4 -
-
5FZR
-
?
A:
[6-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
L
--
S
N
L
A
N
L
L
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
--
N
--
N
I
K
T
-
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
L
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
55.89
29%
-67
- C4 -
-
5FZS
-
?
A:
[16-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
N
I
--
K
T
---
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.79
29%
-70
- C4 -
-
5FZR
-
?
A:
[16-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
N
I
--
K
T
---
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
55.61
20%
12
- C3 -
-
4YUS
1
?
A:
[17-366]
---------------------------------------------------------------------------------------------------------------
M
K
R
L
T
Y
I
S
K
F
S
R
-----------
P
L
S
G
D
E
I
E
A
---------------
I
G
R
I
S
S
-----------
Q
K
N
Q
Q
A
N
V
T
G
V
L
L
C
L
--
D
G
I
F
F
Q
I
L
E
---
G
E
A
E
K
I
D
R
I
Y
E
R
I
L
A
D
E
R
-
H
---
T
---------
D
I
L
C
L
K
S
E
V
---------
E
V
Q
---------------------
E
R
M
--------------
F
P
D
---
W
S
M
Q
T
I
N
L
---
D
E
--
N
T
D
F
-
L
I
R
P
I
K
V
L
L
Q
T
L
T
E
S
H
R
------------
I
L
-------------------
E
K
Y
T
Q
P
S
I
F
K
I
I
S
Q
----------
G
T
N
P
L
N
I
R
----------------------------------------
P
K
A
V
E
K
I
V
F
F
S
D
I
------
V
S
F
S
T
-----------
F
A
E
K
L
P
-----------
V
E
E
V
--
V
S
V
V
N
S
----------------------
Y
--
F
S
V
-
C
T
A
I
I
T
R
--
Q
G
--------
G
E
-
V
T
K
F
I
--------------------------------
G
D
C
--
V
M
A
-----
Y
F
D
G
-
D
C
A
------
D
Q
A
I
---------------------------------
Q
A
S
L
D
I
L
M
E
L
E
I
L
R
N
S
APEGS
P
L
R
V
--
L
Y
S
G
I
G
L
A
K
G
K
V
I
-----
E
G
N
I
G
-------
S
E
L
K
R
--------
D
Y
T
I
L
G
D
A
V
N
V
A
A
R
------
L
E
A
L
T
R
Q
L
--------
S
Q
A
---
L
V
----
F
S
S
E
V
K
N
S
A
T
---
K
--------
S
W
N
F
I
----
W
-
L
T
D
S
E
L
-
K
-
G
K
S
------------------------------
E
S
I
D
-------
I
Y
S
I
D
N
------
E
M
T
R
K
S
S
G
G
L
E
I
A
R
N
I
---
G
H
Y
-
L
E
R
V
-------------------------------
3
PsiBlast_PDB
55.04
29%
-65
- C4 -
-
5FZQ
-
?
A:
[16-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
-
E
G
K
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
-
N
---
I
---------
K
T
L
S
N
L
A
N
L
---------
L
A
Q
---------------------
E
G
K
--------------
A
E
E
A
I
K
Y
M
R
K
A
V
S
L
D
P
N
N
I
--
K
T
---
L
S
N
L
A
V
L
L
A
Q
E
G
K
A
E
E
A
------------
I
K
-------------------
Y
M
R
K
A
V
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
54.05
18%
-61
- C4 -
-
2VYI
-
SGTA_HUMAN
A:
[91-191]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
R
L
--
K
T
E
G
N
E
Q
M
K
-
V
E
N
F
E
A
A
V
H
F
Y
G
K
A
I
E
L
N
P
A
-
N
---
A
---------
V
Y
F
C
N
R
A
A
A
---------
Y
S
K
---------------------
L
G
N
--------------
Y
A
G
A
V
Q
D
C
E
R
A
I
C
I
D
P
--
A
--
Y
S
K
A
-
Y
G
R
M
G
L
A
L
S
S
L
N
K
H
V
E
A
------------
V
A
-------------------
Y
Y
K
K
A
L
E
L
D
P
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
51.58
16%
34
- C1 -
-
4BHW
1
EP300_HUMAN
A:
[14-576]
---------------------------------------------------------------------------------------------------------------
K
K
I
F
K
--
P
E
E
L
R
-----------
Q
A
L
M
P
T
L
E
A
---------------
L
Y
R
Q
DPESLPFRQPVDP
Q
L
L
G
I
P
D
Y
F
D
I
V
K
S
P
M
D
L
S
T
I
K
R
K
L
D
-
T
G
Q
Y
Q
E
P
W
Q
Y
V
D
D
I
W
L
M
F
N
N
-
A
---
W
---------
L
Y
N
R
K
T
S
R
V
---------
Y
K
Y
---------------------
C
S
K
--------------
L
S
E
V
F
E
Q
E
I
D
P
V
M
Q
S
L
G
Y
C
CG
R
K
L
E
-
F
S
P
Q
T
L
C
C
Y
--
G
K
Q
L
C
T
------------
I
P
-------------------
R
D
A
T
Y
Y
S
Y
Q
N
R
Y
H
F
----------
C
E
K
C
F
N
E
I
Q
G
---------------------------
E
S
V
SLGDD
P
S
Q
P
Q
T
T
I
N
K
E
Q
F
S
K
R
K
N
D
T
L
D
P
E
L
F
V
E
C
TECGRKMHQ
I
C
V
L
H
H
E
I
----
I
W
P
A
G
F
V
C
D
--
G
C
L
K
K
S
ARTRKENKFSAKRLPST
R
L
G
T
F
L
--
E
N
R
-
V
N
D
F
L
R
R
--
Q
N
HPE
S
G
E
V
T
V
R
-
V
V
H
A
S
D
K
T
V
E
V
K
P
G
M
K
--------------
A
R
F
V
--
D
S
G
E
--
M
A
E
-----
S
F
P
Y
-
R
T
K
-------
A
L
F
A
----
F
E
E
I
DG
V
D
L
C
F
F
G
M
H
V
Q
E
Y
G
SDCPPPNQ
R
R
V
Y
I
S
Y
L
D
S
V
H
F
F
R
------
P
K
C
L
--
R
T
A
V
Y
H
E
I
L
I
G
Y
L
-----
E
Y
V
K
K
L
--
G
Y
T
-
T
G
H
I
W
ACPPSEGD
D
Y
I
F
H
C
H
P
P
D
Q
K
I
P
------
K
P
K
R
L
Q
E
W
F
K
K
M
L
--
D
K
A
V
S
E
R
I
V
----
H
D
Y
K
D
I
F
K
Q
A
---
T
E
D
RLTSAK
E
L
P
Y
F
----
E
-
G
D
F
W
P
N
-
V
L
E
E
S
I
K
E
S
G
G
---------
S
G
S
Q
K
L
Y
A
T
M
E
K
H
--
K
E
V
F
-------
F
V
I
R
L
I
A
G
P
A
A
N
S
L
P
P
I
V
D
P
D
P
L
I
P
C
D
L
MDG
R
D
A
-
F
L
T
L
A
R
D
K
HLEFSS
L
R
R
A
Q
W
S
T
M
C
M
L
V
E
L
H
T
Q
S
Q
D
36
HHSearch
51.08
18%
-40
- C4 -
-
4I17
1
?
A:
[8-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
L
--
K
N
E
G
N
D
A
L
N
-
A
K
N
Y
A
V
A
F
E
K
Y
S
E
Y
L
K
L
T
N
N
Q
D
---
S
---------
V
T
A
Y
N
C
G
V
C
---------
A
D
N
---------------------
I
K
K
--------------
Y
K
E
A
A
D
Y
F
D
I
A
I
K
K
N
Y
--
N
--
L
A
N
A
-
Y
I
G
K
S
A
A
Y
R
D
M
K
N
N
Q
E
Y
------------
I
A
-------------------
T
L
T
E
G
I
K
A
V
P
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
50.24
10%
-121
- C4 -
-
3GZ1
2
IPGC_SHIFL
A:
[36-136]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
D
I
--
Y
S
Y
A
Y
D
F
Y
N
-
K
G
R
I
E
E
A
E
V
F
F
R
F
L
C
I
Y
D
F
Y
-
N
---
V
---------
D
Y
I
M
G
L
A
A
I
---------
Y
Q
I
---------------------
K
E
Q
--------------
F
Q
Q
A
A
D
L
Y
A
V
A
F
A
L
G
K
--
N
--
D
Y
T
P
-
V
F
H
T
G
Q
C
Q
L
R
L
K
A
P
L
K
A
------------
K
E
-------------------
C
F
E
L
V
I
Q
H
S
N
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
50.00
13%
-89
* C4 *
-
3WXX
-
?
E:
[26-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
Q
L
--
Y
T
L
G
F
N
Q
Y
H
-
A
G
K
H
D
E
A
H
K
I
F
Q
A
L
C
V
L
D
H
Y
-
E
---
A
---------
R
F
F
L
G
L
G
A
C
---------
R
Q
A
---------------------
L
G
Q
--------------
F
R
L
A
I
D
S
Y
S
Y
G
A
M
M
D
L
--
Q
--
E
P
R
F
-
P
F
H
A
A
E
C
L
L
Q
L
G
E
L
E
G
A
------------
E
S
-------------------
G
F
H
S
A
Q
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
49.76
16%
33
* C3 *
-
2QUB
-
?
A:
[1-615]
--------------------------------------------------------------SHMGIFSYKDLD
E
N
A
S
K
A
L
F
S
D
A
L
A
I
S
T
Y
A
Y
HNID
N
G
F
D
E
G
Y
H
Q
TGFGL
G
L
P
L
T
--
L
I
T
A
L
I
G
S
TQ
S
Q
G
GLP
G
L
P
W
N
P
D
S
E
---------------
Q
A
A
Q
-------------
E
A
V
N
N
A
G
W
S
V
I
S
A
T
Q
--
L
G
Y
A
G
K
T
D
A
-
R
G
T
Y
Y
G
E
T
A
G
Y
T
T
A
Q
A
E
V
L
G
-
K
Y
D
S
E
---------
G
N
L
T
A
I
G
I
S
F
R
G
TSGPRE
S
L
I
---------------------
G
D
T
--------------
I
G
D
V
I
N
D
L
L
A
G
F
G
P
K
G
-
Y
A
--
D
G
Y
T
-
L
K
A
F
G
N
L
L
G
D
V
A
K
F
A
Q
A
H
GLSGEDVVVSG
H
S
-------------------
L
G
G
L
A
V
N
S
M
A
A
Q
S
D
ANWGGFYAQ
S
N
Y
V
A
F
A
S
P
T
Q
Y
E
AGGK
V
I
N
I
G
Y
ENDPVFRALDGTSLT
L
P
S
-----
L
G
V
H
D
A
P
H
T
S
A
T
N
N
I
V
N
F
N
D
H
Y
A
S
D
A
W
-----------
N
L
L
P
F
S
I
L
----
N
I
P
T
-
W
L
S
H
L
P
F
F
Y
Q
D
G
----------------------
L
--
M
R
V
-
L
N
S
E
F
Y
S
LT
D
K
--------
D
S
-
T
I
I
V
S
N
L
S
N
V
T
R
G
N
T
W
V
E
DLNRNA
E
T
H
S
G
P
T
F
I
I
--
G
S
D
G
N
D
L
I
K
G
G
K
G
N
D
Y
L
E
G
R
D
G
------
D
D
I
F
R
D
AG
G
Y
N
L
-------------------------
I
A
G
G
K
G
H
N
I
F
D
T
Q
Q
A
------
L
K
N
T
E
V
A
Y
D
G
N
T
L
Y
L
R
D
A
K
-----
G
G
I
T
L
A
D
D
I
S
T
L
R
S
K
E
T
--------
S
W
L
I
F
N
K
E
V
D
H
Q
V
T
AAGLKS
D
S
G
L
K
A
Y
A
A
A
T
G
G
--
D
G
D
D
---
V
L
Q
A
R
S
H
D
A
W
L
F
G
N
A
G
---
N
--------
D
T
L
I
G
H
AGG
N
-
L
T
F
V
G
G
-
S
-
G
D
D
I
L
K
G
V
G
---------
N
G
N
T
F
L
F
S
--
G
D
F
G
R
D
Q
L
Y
GFNAS
D
K
L
V
F
I
G
T
E
G
A
S
G
N
I
R
D
Y
A
T
Q
Q
N
D
D
L
V
L
A
F
---
G
H
----
S
Q
V
T
L
I
----------
G
V
S
L
D
H
I
S
T
D
Q
VVLA--
28
HHSearch
49.17
13%
-25
- C4 -
-
3UPV
-
A:
[5-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
--
R
L
E
G
K
E
Y
F
T
-
K
S
D
W
P
N
A
V
K
A
Y
T
E
M
I
K
R
A
P
E
-
D
---
A
---------
R
G
Y
S
N
R
A
A
A
---------
L
A
K
---------------------
L
M
S
--------------
F
P
E
A
I
A
D
C
N
K
A
I
E
K
D
P
--
N
--
F
V
R
A
-
Y
I
R
K
A
T
A
Q
I
A
V
K
E
Y
A
S
A
------------
L
E
-------------------
T
L
D
A
A
R
T
K
D
A
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
48.33
16%
-61
- C4 -
-
3Q4A
-
CHIP_MOUSE
B:
[10-109]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
L
--
K
E
Q
G
N
R
L
F
V
-
G
R
K
Y
P
E
A
A
A
C
Y
G
R
A
I
T
R
N
P
L
-
V
---
A
---------
V
Y
Y
T
N
R
A
L
C
---------
Y
L
K
---------------------
M
Q
Q
--------------
P
E
Q
A
L
A
D
C
R
R
A
L
E
L
D
G
--
Q
--
S
V
K
A
-
H
F
F
L
G
Q
C
Q
L
E
M
E
S
Y
D
E
A
------------
I
A
-------------------
N
L
Q
R
A
Y
S
L
A
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.17
17%
-1
- C4 -
-
1ELW
2
STIP1_HUMAN
A:
[5-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
L
--
K
E
K
G
N
K
A
L
S
-
V
G
N
I
D
D
A
L
Q
C
Y
S
E
A
I
K
L
D
P
H
-
N
---
H
---------
V
L
Y
S
N
R
S
A
A
---------
Y
A
K
---------------------
K
G
D
--------------
Y
Q
K
A
Y
E
D
G
C
K
T
V
D
L
K
P
--
D
--
W
G
K
G
-
Y
S
R
K
A
A
A
L
E
F
L
N
R
F
E
E
A
------------
K
R
-------------------
T
Y
E
E
G
L
K
H
E
A
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
47.83
14%
-27
- C4 -
-
4CGW
-
RPAP3_HUMAN
A:
[15-116]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
Q
A
I
S
E
--
K
D
R
G
N
G
F
F
K
-
E
G
K
Y
E
R
A
I
E
C
Y
T
R
G
I
A
A
D
G
A
-
N
---
A
---------
L
L
P
A
N
R
A
M
A
---------
Y
L
K
---------------------
I
Q
K
--------------
Y
E
E
A
E
K
D
C
T
Q
A
I
L
L
D
G
--
S
--
Y
S
K
A
-
F
A
R
R
G
T
A
R
T
F
L
G
K
L
N
E
A
------------
K
Q
-------------------
D
F
E
T
V
L
L
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------