@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLW1: (2017-11-04 )
MNQLELKKVIRPVILIVALMIAVYTIVHLWNYYNAAPWTRDGRVRGDVIQVSSDVAGLVTEVLVQDNQTVKKGQVLFKIDVSRRALDVEQAKSDLAKAKAAYAQAQAGLAQAKANLIKSSTNIKLAEKNANRYSNLMDGAISKQEQDQVFATRDQSHAEHEQLQAAIQQAEATIKQQQALVEAATSNLHLAELNMHRAAVVAPADGTLSNFDLRPGNYVQVGQAVAALLDRKQLYVVGYFEETKLDRIHIGDEATVQLMGDRQKIKGHVQGIASGIEDRERSSSSKLLANVNPTFSWVRLAQRVPVKIVLDEAPKNELAFVSGRTAKVHIIEK
Atome Classification :
(20 SA)
.........10........20........30........------40.....---.---.-----------.50........60..-......70........80........90......------------------------..100.----...-------------------------...110.......120.......130.....-.-.-140...-.....150..--.....160...--------------..----------..170.......180.......190----------------------.--........200.......210.......220-..---.---.....---230.......240.......250--..---------.......260.-.--......270.......280.......290.......300.......310.......320.......330.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
N
Q
L
E
L
K
K
V
I
R
P
V
I
L
I
V
A
L
M
I
A
V
Y
T
I
V
H
L
W
N
Y
YNAAPWT------RDGRVRG---
D
---
V
-----------
I
Q
VS
S
D
V
A
G
L
V
T
E
V
L
-VQDNQTVKKG
Q
V
L
F
K
I
DVSRRAL
D
V
E
Q
A
K
S
D
L
A
K
------------------------
A
K
A
A
Y
A
----
Q
A
Q
-------------------------
A
G
L
A
Q
A
K
A
N
L
IKSST
N
I
K
L
AEKN
A
N
R
Y
S
N
L
M
-D-G-A-ISKQ-EQD
Q
V
F
ATRD--QSH
A
E
H
E
Q
L
Q
A
--------------
A
I
----------
Q
Q
A
E
A
T
I
K
Q
Q
Q
A
L
V
E
A
A
TSN
L
H
L
------------------------
A
--
E
LNM
H
R
A
A
V
VAPADGTLSNFDLRPG
N
Y
V
Q
-
V
-
G
Q
---
A
---
V
A
A
L
L---DRK
Q
L
Y
V
V
G
Y
F
EETKL
D
R
I
H
I----GD---------
E
A
T
V
Q
L
MG-
D
R
-
Q
--
K
I
K
G
H
V
Q
G
I
A
S
G
I
E
D
RERSSSS
K
L
L
ANVNP
T
F
S
W
V
R
L
A
Q
RV
P
V
K
I
V
LDEAPKN
E
L
A
F
VSG
R
T
A
K
V
H
I
IEK
21
HHSearch
77.60
21%
63
- C1 -
-
4TKO
2
?
B:
[7-348]
-----------------------------------
Y
A
I
T
------
N
A
V
F
V
K
A
D--
E
---
L
-----------
S
Y
L
S
F
R
V
S
G
K
V
I
E
V
Y
-
K
D
L
G
D
Y
V
K
R
G
E
A
L
A
K
L
D
P
T
Y
Y
E
L
E
K
R
T
L
E
K
K
M
S
A
------------------------
L
L
E
K
K
K
----
A
L
E
IKIQKLEKGLHISLSAKKLKVESLK
K
K
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
K
L
V
K
L
D
W
E
R
Y
K
S
L
F
-
Q
-
K
-
G
-
L
I
P
R
R
K
F
E
E
V
D
T
N
L
K
--
V
L
L
H
E
R
E
Y
L
E
K
SIQEINTEIKRAKK
G
I
ENARNEFKTI
E
E
L
K
K
E
L
S
S
L
E
E
E
I
K
S
L
K
E
R
I
K
T
------------------------
A
--
E
Q
K
I
K
D
T
V
L
I
A
P
F
D
G
V
V
A
K
R
F
I
S
R
G
D
V
V
R
-
A
-
G
Q
---
P
---
A
F
A
L
V
---
N
P
E
S
F
Y
V
E
V
L
L
E
E
T
K
L
K
G
V
K
V
----
G
N
---------
K
A
Y
V
R
L
D
A
-
Y
P
D
I
--
L
F
E
G
V
V
E
E
I
S
P
--------------------------
V
Q
R
I
P
V
K
I
K
I
T
K
G
D
L
--
S
L
L
R
V
G
M
G
G
E
V
E
I
R
R
-
42
Fugue
76.17
21%
11
- C1 -
-
4TKO
2
?
B:
[3-349]
---
H
R
I
E
Y
A
I
T
N
A
V
F
V
K
A
D
E
L
S
Y
L
S
------
F
R
V
S
G
K
V
I
------
E
V
Y
K
D
L
G
---
D
---
Y
-----------
V
K
R
G
E
A
L
A
K
L
D
P
T
Y
Y
-
E
L
E
K
R
T
L
E
K
K
M
S
A
L
L
E
K
K
K
A
L
E
I
K
I
Q
K
L
E
K
G
L
H
I
------------------------
S
L
S
A
K
K
LKVE
S
L
K
-------------------------
K
K
R
E
A
L
R
E
K
L
L
Q
V
E
E
K
I
K
L
V
K
L
D
W
E
R
Y
K
S
L
F
-
Q
K
G
-
L
-
I
P
R
R
-
K
F
E
E
V
D
T
N
L
K
--
V
L
L
H
E
R
E
Y
L
E
K
--------------
S
I
----------
Q
E
I
N
T
E
I
K
R
A
K
K
G
I
E
N
A
R
N
E
F
K
T
IEELKKELSSLEEEIKSLKERIKT
A
--
E
Q
K
I
K
D
T
V
L
I
A
P
F
D
G
V
V
A
K
R
F
I
S
R
G
D
V
V
R
-
A
-
G
Q
---
P
---
A
F
A
L
V
---
N
P
E
S
F
Y
V
E
V
L
L
E
E
T
K
L
K
G
V
K
V
----
G
N
---------
K
A
Y
V
R
L
D
A
Y
P
D
-
I
--
L
F
E
G
V
V
E
E
I
S
P
--------------------------
V
Q
R
I
P
V
K
I
K
I
T
K
G
D
L
S
L
L
R
--
V
G
M
G
G
E
V
E
I
R
R
T
43
Fugue
71.51
19%
-46
- C1 -
-
3FPP
-
MACA_ECOLI
A:
[43-308]
------
P
G
D
L
Q
Q
S
V
L
A
T
G
K
L
D
A
L
--------------------------------
R
---
K
-----------
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
------------------------
L
R
A
Q
R
Q
----
Q
A
E
-------------------------
A
E
L
K
L
A
R
-------------------------------
V
T
Y
S
-
R
Q
Q
R
L
A
Q
T
Q
A
--
V
S
Q
Q
D
L
D
N
A
A
T
--------------
E
M
----------
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
------------------------
A
--
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
---
Q
A
P
N
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
L
T
--
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
A
I
F
Y
Y
A
R
F
E
V
P
N
P
N
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
---------------
27
HHSearch
65.96
21%
26
- C1 -
-
3LNN
-
?
A:
[42-281]
-----------------------------------
A
P
F
N
------
L
P
A
M
I
E
A
DPA
K
---
L
-----------
V
K
V
L
P
P
L
A
G
R
I
V
S
L
N
-
K
Q
L
G
D
E
V
K
A
G
D
V
L
F
T
I
D
S
A
D
L
A
Q
A
N
S
----
D
A
A
--------------------------------------------------------------------------
K
A
R
A
A
M
T
M
A
R
R
N
L
D
R
Q
R
E
L
D
-
K
-
S
-
E
-
I
A
A
K
R
D
F
E
Q
A
---------
Q
S
D
Y
D
Q
A
A
S
--------------
E
S
-----------------
Q
R
A
D
A
R
L
A
Q
L
G
A
K
G
G
G
------------------------
T
LQ
A
G
G
G
H
I
L
A
V
R
S
P
I
N
G
R
V
V
D
L
N
A
A
T
G
A
Y
W
N
-
D
T
T
A
---
S
---
L
M
T
V
A
---
D
L
S
H
V
F
V
T
A
N
A
Q
E
K
D
L
G
H
V
Y
V
----
G
Q
---------
S
A
T
V
K
F
D
A
-
Y
D
-
D
--
P
Q
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
T
R
---------------------
T
T
K
V
R
M
V
F
D
N
P
D
---
G
R
L
R
P
G
M
F
A
Q
A
T
F
L
--
22
HHSearch
65.85
20%
53
- C1 -
-
5NIK
-
?
G:
[50-300]
-------------------------------------
V
L
------
A
T
G
K
L
D
A
L--
R
---
K
-----------
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
------------------------
L
R
A
Q
R
Q
-------------------------------------------
Q
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
-
Q
-
T
-
Q
-
A
V
S
Q
-
Q
---------------
D
L
D
N
A
A
T
--------------
E
M
----------
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
------------------------
A
--
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
QAP
N
---
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
L
T
--
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
-------------------
A
I
F
Y
Y
A
R
F
E
V
P
N
P
N
---
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
-
23
HHSearch
65.17
20%
48
- C1 -
-
3FPP
-
MACA_ECOLI
B:
[48-300]
-----------------------------------
Q
S
V
L
------
A
T
G
K
L
D
A
L--
R
---
K
-----------
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
------------------------
L
R
A
Q
R
Q
----
Q
---------------------------------------
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
-
Q
-
T
-
Q
-
A
V
S
Q
-
Q
---------------
D
L
D
N
A
A
T
--------------
E
M
----------
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
------------------------
A
--
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
Q
A
P
N
---
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
L
T
--
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
N
D
-------------------
A
I
F
Y
Y
A
R
F
E
V
P
N
P
N
---
G
L
L
R
L
D
M
T
A
Q
V
H
I
Q
L
-
1
PsiBlast_PDB
63.35
23%
46
- C1 -
-
3LNN
-
?
A:
[41-266]
----------------------------------
A
A
P
F
N
------
L
P
A
M
I
E
A
---
D
PAK
L
-----------
V
K
V
L
P
P
L
A
G
R
I
V
S
L
N
-
K
Q
L
G
D
E
V
K
A
G
D
V
L
F
T
I
D
S
A
----
D
L
A
Q
A
N
S
D
A
A
K
------------------------
A
R
A
A
--------------------------------------------------
M
T
M
A
R
R
N
L
D
R
Q
R
E
L
-------------
D
K
S
E
I
A
A
K
R
D
F
E
Q
A
Q
S
D
Y
D
Q
A
A
S
--------------
E
S
----------
Q
R
A
D
A
R
L
A
Q
L
-----
G
A
K
G
G
G
T
L
------------------------
Q
--
A
G
G
G
H
I
L
A
V
R
S
P
I
N
G
R
V
V
D
L
N
A
A
T
G
A
Y
W
N
D
T
-
T
A
---
S
---
L
M
T
V
A
---
D
L
S
H
V
F
V
T
A
N
A
Q
E
K
D
L
G
H
V
Y
V
----
G
Q
---------
S
A
T
V
K
F
D
A
-
Y
D
-
D
--
P
Q
P
G
K
V
R
Y
V
G
Q
I
L
D
A
D
T
R
T
T
K
V
R
M
V
F
D
-
N
P
----------------------------------------
24
HHSearch
62.15
22%
38
- C1 -
-
2F1M
-
ACRA_ECOLI
D:
[54-297]
-------------------------------------
T
E
------
L
P
G
R
T
S
A
Y--
R
---
I
-----------
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
-
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
------------------------
A
Q
A
--------------------------------------------------
A
A
N
I
A
Q
L
T
V
N
R
Y
Q
K
L
L
-
G
-
T
-
Q
-
Y
I
S
K
-----------------------
Q
--------------
E
Y
----------
D
Q
A
L
A
D
A
Q
Q
A
N
A
A
V
T
A
A
K
A
A
V
E
T
------------------------
A
--
R
I
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
-
N
-
G
Q
AT-
A
---
L
A
T
V
Q
---
Q
L
D
P
I
Y
V
D
V
T
Q
S
--------------
G
---------
K
A
K
V
S
L
I
T
-
S
D
G
I
KF
P
Q
D
G
T
L
E
F
S
D
V
T
V
D
Q
T
T
---------------------
G
S
I
T
L
R
A
I
F
P
N
P
D
---
H
T
M
M
P
G
M
F
V
R
A
R
L
---
30
HHSearch
60.84
21%
39
* C1 *
-
2V4D
-
MEXA_PSEAE
G:
[27-261]
-----------------------------------
L
N
T
E
------
L
P
G
R
T
N
A
F--
R
---
I
-----------
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
-
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
------------------------
T
Q
---------------------------------------------------------
E
Q
A
Q
R
Y
K
L
L
V
-
A
-
D
-
Q
-
A
V
S
K
-----------------------
Q
-------------------------------
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
------------------------
A
--
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
-
N
-
G
Q
---
A
NA-
M
A
T
V
Q
---
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
V
S
L
K
L
E
D
-
G
S
Q
Y
--
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
---------------------
G
S
V
T
I
R
A
V
F
P
N
P
N
---
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
E
-
4
PsiBlast_PDB
59.54
25%
38
- C1 -
-
5NIL
-
?
D:
[32-251]
-----------------------------------
P
V
P
T
YQTLIV
R
P
G
D
L
Q
Q
---
S
---
V
LATGKLDALRK
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
-------
D
P
E
Q
A
E
N
Q
I
K
E
------------------------
V
E
A
T
L
M
----
E
L
R
-------------------------
A
Q
R
Q
Q
A
E
A
E
L
-------
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
-
Q
-
T
Q
A
-
V
S
Q
Q
-
D
-------
L
D
--
N
A
A
T
E
M
A
V
K
Q
A
--------------
Q
I
----------
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
------------------------
T
--
R
-------
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
---
Q
APN
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
--------------------------------------------------------------------------
3
PsiBlast_PDB
59.54
25%
38
- C1 -
-
5NIK
-
?
D:
[32-251]
-----------------------------------
P
V
P
T
YQTLIV
R
P
G
D
L
Q
Q
---
S
---
V
LATGKLDALRK
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
-------
D
P
E
Q
A
E
N
Q
I
K
E
------------------------
V
E
A
T
L
M
----
E
L
R
-------------------------
A
Q
R
Q
Q
A
E
A
E
L
-------
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
-
Q
-
T
Q
A
-
V
S
Q
Q
-
D
-------
L
D
--
N
A
A
T
E
M
A
V
K
Q
A
--------------
Q
I
----------
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
------------------------
T
--
R
-------
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
---
Q
APN
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
--------------------------------------------------------------------------
6
PsiBlast_PDB
59.47
25%
-11
- C1 -
-
3FPP
-
MACA_ECOLI
A:
[62-251]
-----------------------------------------------------------------------
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
-
V
A
I
G
D
K
V
K
K
D
Q
L
L
G
V
I
-------
D
P
E
Q
A
E
N
Q
I
K
E
------------------------
V
E
A
T
L
M
----
E
L
R
-------------------------
A
Q
R
Q
Q
A
E
A
E
L
-------
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
-
Q
-
T
Q
A
-
V
S
Q
Q
-
D
-------
L
D
--
N
A
A
T
E
M
A
V
K
Q
A
--------------
Q
I
----------
G
T
I
D
A
Q
I
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
------------------------
T
--
R
-------
I
V
A
P
M
A
G
E
V
T
Q
I
T
T
L
Q
G
Q
T
V
I
-
A
-
A
Q
---
Q
A
P
N
I
L
T
L
A
---
D
M
S
A
M
L
V
K
A
Q
V
S
E
A
D
V
I
H
L
K
P
----
G
Q
---------
K
A
W
F
T
V
L
G
-
D
Q
--------------------------------------------------------------------------
29
HHSearch
59.32
21%
36
- C1 -
-
1VF7
-
MEXA_PSEAE
J:
[27-260]
-----------------------------------
L
N
T
E
------
L
P
G
R
T
N
A
F--
R
---
I
-----------
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
-
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
---------------------------------------------------------------------------------
T
Q
E
Q
A
Q
R
Y
K
L
L
V
-
A
-
D
-
Q
-
A
V
S
K
-----------------------
Q
-------------------------------
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
------------------------
A
--
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
-
N
-
G
Q
---
A
NA-
M
A
T
V
Q
---
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
R
R
ELAS
G
Q
LERAGDNAA
K
V
S
L
K
L
E
D
-
G
S
Q
Y
--
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
---------------------
G
S
V
T
I
R
A
V
F
P
N
P
N
---
N
E
L
L
P
G
M
F
V
H
A
Q
L
Q
--
44
Fugue
57.65
16%
-65
- C1 -
-
1T5E
1
MEXA_PSEAE
A:
[29-259]
---
T
E
L
P
G
R
T
N
A
F
------------------------------------------
R
---
I
-----------
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
-
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
------------------------
T
Q
E
Q
A
Q
----
R
Y
K
-------------------------
L
L
V
A
D
Q
A
V
S
--------------------------------------------------------------------------------------
K
Q
Q
Y
A
D
A
N
A
A
Y
L
Q
S
K
A
A
V
E
Q
------------------------
A
--
R
I
N
L
R
Y
T
K
V
L
S
P
I
S
G
R
I
G
R
S
A
V
T
E
G
A
L
V
T
-
N
-
G
Q
---
A
---
N
A
M
A
T
---
V
Q
Q
L
D
P
I
Y
V
D
V
T
Q
P
S
T
A
L
L
R
L
----
R
R
---------
E
L
A
---
S
G
-
Q
L
-
E
--
R
A
G
D
N
A
A
K
V
S
L
K
L
E
D
G
S
Q
Y
P
L
E
G
R
L
E
F
S
E
V
S
V
D
E
G
T
G
S
V
T
I
R
A
V
F
-----
P
N
P
N
N
E
L
L
P
G
M
F
V
H
A
Q
L
---
36
HHSearch
55.72
20%
-24
- C1 -
-
4KKS
-
?
A:
[40-207]
------------------------------------
Y
L
S
------
L
N
G
D
V
D
T
K--
V
---
K
-----------
A
D
I
F
P
D
A
V
G
K
I
T
S
L
R
-
I
K
L
G
A
Y
V
Q
K
G
Q
I
V
A
T
L
D
P
S
R
P
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
L
K
S
P
V
R
A
P
I
S
G
Y
I
L
N
I
T
K
K
I
G
E
T
V
N
-
P
-
Q
S
---
N
---
I
A
V
V
G
---
R
I
D
T
K
Q
I
L
T
Y
V
S
E
K
Y
I
S
N
I
K
V
----
G
N
---------
D
A
I
I
E
V
G
A
-
Y
S
N
E
--
K
F
K
A
K
V
S
E
I
S
P
I
L
D
S
K
S
R
---------------------
T
I
E
V
Y
L
T
P
I
G
S
N
L
--
D
K
L
I
I
G
M
F
S
K
I
K
L
I
T
-
12
PsiBlast_PDB
54.96
27%
-11
- C1 -
-
2F1M
-
ACRA_ECOLI
A:
[65-219]
-----------------------------------------------------------
I
-----------
A
E
V
R
P
Q
V
S
G
I
I
L
K
R
N
-
F
K
E
G
S
D
I
E
A
G
V
S
L
Y
Q
I
D
P
A
T
Y
Q
A
T
Y
D
S
A
K
G
D
L
A
K
------------------------
A
Q
A
A
A
N
----
I
A
Q
-------------------------
L
---------------------
T
V
N
R
Y
Q
K
L
L
-
G
-
T
-
Q
Y
I
S
K
Q
-
E
Y
D
Q
A
L
A
D
------------------------------
A
----------
Q
Q
A
N
A
A
V
T
A
A
K
A
A
V
E
T
-------------------------------
A
--
R
I
N
L
A
Y
T
K
V
T
S
P
I
S
G
R
I
G
K
S
N
V
T
E
G
A
L
V
Q
-
N
-
G
Q
---
A
---
T
A
-------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
54.89
23%
0
- C- -
-
4DK0
-
?
A:
[56-273]
-------------------------------------------------------
N
---
T
-----------
V
D
V
G
A
Q
V
S
G
K
I
T
K
L
Y
-
V
K
L
G
Q
Q
V
K
K
G
D
L
L
A
E
I
D
S
T
T
Q
I
-------
N
T
L
N
T
------------------------
R
K
A
A
------------------------------------
L
A
S
Y
Q
A
Q
L
V
A
R
K
T
A
Y
D
V
A
L
S
N
Y
Q
R
L
S
K
L
Y
G
Q
-
K
-
A
-
T
S
L
D
-
T
L
N
T
A
K
A
T
L
N
--
N
A
K
A
E
M
D
V
V
Q
E
--------------
N
I
----------
K
Q
A
E
I
E
V
--------------
N
T
------------------------
A
--
E
T
N
L
G
Y
T
K
I
T
S
P
I
D
G
T
V
I
S
T
P
V
S
E
G
Q
T
V
N
-
S
-
N
Q
---
T
---
T
P
T
I
I
K
V
A
D
L
S
K
M
R
I
K
P
E
I
S
E
G
D
I
T
K
V
K
A
----
G
Q
---------
D
V
T
F
T
I
L
S
-
D
N
-
K
--
T
V
--------------------------------------------------------------------
33
HHSearch
54.57
16%
27
- C1 -
-
3T53
-
CUSB_ECOLI
C:
[30-242]
------------------------------------
A
Q
S
------
F
P
A
N
V
S
Y
---
N
EYQ
Y
-----------
A
I
V
Q
A
R
A
A
G
F
I
D
K
V
Y
P
L
T
V
G
D
K
V
Q
K
G
T
P
L
L
D
L
T
I
P
D
W
V
E
A
Q
S
E
----
Y
L
L
------------------------
L
R
E
---------------------------------------------------------------------
T
-
G
-
G
T
A
T
-
Q
T
E
G
I
---------
L
E
R
L
R
L
A
G
----------------
M
-------------------
P
E
A
D
I
R
R
----
L
I
A
------------------------
T
--
Q
K
I
Q
T
R
F
T
L
K
A
P
I
D
G
V
I
T
A
F
D
L
R
A
G
M
N
I
A
-
K
-
D
N
---
V
---
V
A
K
I
Q
---
G
M
D
P
V
W
V
T
A
A
I
P
E
S
I
A
W
L
V
K
D
----
A
S
---------
Q
F
T
L
T
V
P
A
-
R
P
D
K
--
T
L
T
I
R
K
W
T
L
L
P
G
V
D
A
A
T
R
---------------------
T
L
Q
L
R
L
E
V
D
N
A
D
---
E
A
L
K
P
G
M
N
A
W
L
Q
L
N
T
-
9
PsiBlast_PDB
53.50
26%
-208
- C1 -
-
1VF7
-
MEXA_PSEAE
A:
[40-132]
-----------------------------------------------------------
I
-----------
A
E
V
R
P
Q
V
N
G
I
I
L
K
R
L
-
F
K
E
G
S
D
V
K
A
G
Q
Q
L
Y
Q
I
D
P
A
T
Y
E
A
D
Y
Q
S
A
Q
A
N
L
A
S
T
Q
E
Q
A
Q
R
Y
K
L
L
V
A
D
QAVS
K
Q
Q
Y
A
D
A
N
A
A
Y
L
----
Q
S
K
-------------------------
A
A
V
E
Q
A
R
I
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
52.42
19%
19
- C1 -
-
4L8J
4
?
A:
[22-209]
------------------------------------
L
K
D
------
F
S
G
M
V
E
A
V
--
E
---
Y
-----------
V
K
L
A
F
R
V
S
G
Q
I
I
N
L
P
-
V
V
E
G
Q
R
V
K
K
G
Q
L
I
A
A
I
D
P
R
D
I
S
L
Q
Y
A
A
D
K
A
---------------------------------------------------------------------------------
A
Y
E
T
A
A
A
Q
V
E
R
N
K
R
L
L
-
G
-
R
-
Q
-
A
I
S
L
-----------------------
Q
--------------
E
Y
-----------------
E
I
S
V
A
N
Y
Q
K
A
K
S
A
Y
E
L
------------------------
S
--
T
N
N
M
R
D
T
K
L
L
A
P
F
D
G
S
I
E
T
R
L
V
E
N
Y
Q
R
V
N
-
S
-
G
E
---
G
---
I
V
R
L
V
---
N
T
R
K
L
R
I
K
F
T
V
P
D
D
Y
L
Y
L
L
R
A
----
K
D
A
--------
T
F
K
V
E
F
D
T
-
Y
K
G
T
--
V
F
N
A
R
L
E
E
Y
L
D
I
S
---------------------------------------------------------