@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLW3: (2017-11-04 )
MLLKQILAFRPSKLDLIFAIKTFIAGRLALFVSFELDLINPMWSIGTVLIIANPYSGMVSSKCVYRLLGTVGGAIIALTITPHLINTPWIFTVVLSLWVGFALYVSLLDRTPRSYAFMLAGYSTAMIMYNAITYIDQYNIFDIALARVLEISIGVISSAVVSATILPMHIGSAIKQRVTKTLKDTENLFANLLNADQQQNNTQLLAAITRDTTDIHALAVHLSYEKGELHGMTKPLQEMLHQMSMVVANLVALSERIKQLQELNFIESHSDKLKQLSGHVIHFLEQKDQMTDENILQLPDEFENDFLNLNDSASEHQQVLLAAMKMDVRHFISNVLAVKVLWQRIKQGNKEIPDNITPMTTKYPSLHRDHGVAVRGGISAELITFIVTGVWILSGWKAGFMMAQIGAVIACILTALDNPVPVLRIFIWGSVASAVLVFIYAFGIFPHVTTFWELGLVLLPMFLFAVSMMANQALMPVGMVLGINTMMGLNLHNAYSMDAVSYLDSSFGMVMGVLVSLVVIDVVRAMSPDTSANRILALHYRAMRQAIYIPYGIEFKVHLRGMLDRVGVLNTKMVQSEEIKKSIQQALVESSAIIDLSRLQELANQVPTSSELAHHIGRLQQDLDELFRAKENEKGESDVLVQHIHQTLFELKQLASNIEDMTLRQRLFISLNNIAYSMCHVSSNQMNVDRTLTGATAHG
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250...-----....260.......270.......280.......290.--......300.......310.......320.......330.......340.......350.......360.......370.---------......380.......390.......400.......410.......420.......430.......-440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570..--.....580.......590.......600.......610.......620-------.........630.......-----640......---.650...-------....660.......670.......680.......690.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
L
L
K
Q
I
L
A
FRPSKL
D
L
I
F
A
I
K
T
F
IAG
R
L
A
L
F
V
S
F
E
L
DLINPMWSI
G
T
V
L
I
I
ANPYSG
M
V
S
S
K
C
V
Y
R
L
L
G
TVGG
A
I
I
A
L
T
ITPHLINT
P
W
I
F
T
V
V
L
S
L
W
V
G
F
A
L
Y
V
S
L
L
DRTPR
S
Y
A
F
M
LAGY
S
T
A
M
I
M
Y
N
A
I
T
Y
IDQY
N
I
F
D
I
A
L
A
R
V
L
E
I
S
I
G
V
I
S
S
A
V
V
S
A
T
I
L
P
M
H
I
G
S
A
I
K
Q
R
V
T
K
T
L
K
D
T
E
N
L
F
A
N
L
LNADQQQNN
T
Q
L
L
A
A
ITRDTT
D
I
H
A
L
A
V
H
L
S
YEKGELHG
M
T
K
P
L
Q
E
M
L
H
Q
M
S
M
V
V
A
N
L
V
A
L
S
E
-----
R
I
K
Q
L
Q
E
L
N
F
I
E
S
H
S
D
K
L
K
Q
LS
G
H
V
I
H
F
L
E
Q
K
DQMT
D
E
--
N
I
L
QL
P
D
E
FENDFLNLNDS
A
S
E
H
Q
Q
V
L
L
A
A
M
K
M
D
V
R
H
F
I
S
N
V
L
A
V
K
V
L
W
Q
R
I
KQGNKEIPDNITPMTTKYPSLHRDH
G
V
A
---------VRGG
I
S
A
E
L
I
T
F
I
V
T
G
V
W
I
LSGWK
A
G
F
M
M
A
Q
I
G
A
V
I
A
C
I
L
T
ALDNPV
P
V
L
R
I
F
I
W
G
S
V
A
S
A
V
L
V
F
I
-
Y
A
F
GIFP
H
V
T
T
F
W
E
L
G
L
V
L
L
P
M
F
L
F
A
V
S
M
M
ANQ
A
L
M
P
V
G
M
V
LGI
N
T
M
M
G
L
N
LHNAYS
M
D
A
V
S
Y
L
D
S
S
F
G
M
V
M
G
V
L
V
S
L
V
V
I
D
V
V
R
AMSPDTSA
N
R
I
L
A
L
H
Y
R
A
M
R
Q
A
I
YIPYG
I
E
F
K
V
H
L
R
G
M
L
D
R
VGVLN
T
K
MV--
Q
S
E
E
I
K
K
S
I
Q
Q
A
L
V
E
S
S
A
II
D
L
S
R
L
Q
E
L
A
N
QVP
T
S
S
E
L
A
H
H
I
G
R
L
Q
---------
Q
D
L
D
E
L
F
R
AKENEKG
E
S
D
V
-----
L
V
Q
H
I
H
Q
T
L
---
F
E
L
K
Q
L
A
-------
S
N
I
E
D
M
T
L
R
Q
R
L
F
I
S
L
N
N
I
A
Y
S
M
C
HVSSNQMNVDRTLTGATAHG
16
PsiBlast_PDB
73.90
23%
-
- C1 -
-
3O4X
-
?
A:
[247-356]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
T
P
A
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
19
PsiBlast_PDB
65.81
27%
-181
- C1 -
-
3QNQ
5
?
A:
[178-264]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
V
T
R
S
F
A
A
L
---------
I
P
G
F
I
-------
V
V
T
V
V
W
I
I
---
R
L
I
F
E
H
T
T
F
G
S
I
H
N
V
V
G
K
L
L
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
L
V
H
V
L
W
A
C
G
I
--
H
G
A
T
I
--
V
G
G
V
M
S
P
I
W
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
60.90
23%
60
- C1 -
-
1Z2C
-
DIAP1_MOUSE
B:
[179-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
15
PsiBlast_PDB
60.39
23%
52
- C1 -
-
3EG5
-
?
B:
[179-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
14
PsiBlast_PDB
59.97
23%
58
- C1 -
-
2F31
-
DIAP1_MOUSE
A:
[113-222]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
12
PsiBlast_PDB
59.39
23%
62
- C1 -
-
2BNX
-
?
A:
[117-231]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
17
PsiBlast_PDB
58.57
23%
73
- C1 -
-
3OBV
1
?
A:
[117-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
18
PsiBlast_PDB
58.39
23%
68
- C1 -
-
4UWX
1
DIAP1_MOUSE
A:
[117-226]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
13
PsiBlast_PDB
58.14
23%
76
- C1 -
-
2BAP
-
DIAP1_MOUSE
B:
[113-222]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
A
A
K
L
L
S
A
L
C
I
LP
Q
P
E
D
M
N
E
R
V
L
E
A
M
T
E
R
A
E
M
D
E
V
E
R
F
Q
P
L
L
D
G
L
K
S
G
T
S
I
A
L
K
V
G
C
L
Q
L
I
N
A
L
I
TPA
E
E
L
D
--
F
R
V
H
I
----
R
S
E
L
-----
M
R
L
G
L
H
Q
V
L
---
Q
E
L
R
E
I
E
-------
N
--
E
D
M
K
V
Q
L
C
V
F
-------------------------------
38
Fugue
57.94
19%
-22
- C2 -
-
2JVG
-
SBI_STAAM
A:
[195-266]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
M
V
S
I
E
K
A
I
V
--
R
H
D
E
R
V
K
S
A
N
D
A
I
S
K
L
N
E
K
D
S
I
E
N
R
R
L
A
Q
R
E
V
N
K
A
P
--
M
D
V
K
E
H
L
Q
---------
K
Q
L
D
A
L
V
A
Q
K
D
A
E
K
K
V
A
-----------------------------------------------------------------------------
37
Fugue
56.96
11%
-55
- C2 -
-
4FLA
-
RPR1B_HUMAN
A:
[23-148]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
E
L
I
K
A
L
Q
D
L
E
N
A
A
S
G
D
A
T
V
R
Q
K
I
A
S
-----
L
P
Q
E
V
Q
D
V
S
L
L
E
K
I
T
D
K
E
A
A
E
R
L
S
K
T
V
D
E
A
C
L
L
L
A
E
Y
N
--
G
R
L
A
A
E
L
E
D
R
R
Q
L
A
R
M
L
V
E
Y
T
Q
N
Q
K
D
V
L
S
E
K
E
K
K
L
E
E
Y
K
Q
K
L
A
R
V
T
Q
V
R
K
E
L
K
S
H
I
Q
S
L
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.07
28%
-2
- C1 -
-
3K6J
-
?
A:
[89-173]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
C
K
---------
Q
E
L
E
V
M
Y
A
R
E
K
S
F
K
R
L
N
D
K
-----
R
I
E
K
I
N
A
N
L
K
I
T
S
D
F
H
K
L
S
NCD
L
I
V
E
S
V
I
E
D
M
K
L
K
K
E
L
F
A
N
L
E
N
I
C
K
S
T
C
I
F
G
T
N
T
S
S
L
D
----------
5
PsiBlast_PDB
53.21
26%
89
- C1 -
-
5SZI
-
B:
[85-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
D
H
Q
S
R
L
E
---------
Q
K
L
R
E
K
M
L
K
E
E
S
Q
K
D
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
M
Q
V
I
---
E
Q
R
D
K
L
V
-------
D
S
L
E
E
Q
R
I
R
E
K
---------------------------------
29
Fugue
52.72
9%
8
- C2 -
-
2YFA
2
MCPS_PSEPK
A:
[18-253]
---------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
G
D
I
G
Q
L
N
K
D
L
T
D
L
R
I
A
R
L
Q
Y
M
I
A
N
G
D
D
T
A
A
A
N
T
L
A
K
L
D
A
F
S
K
Q
Q
A
Y
L
A
T
T
F
K
S
P
E
N
V
K
L
L
G
E
L
G
D
T
I
S
A
Y
K
L
S
L
N
K
M
R
Q
G
Y
D
A
T
R
A
A
R
V
S
M
D
S
S
A
I
R
A
D
Q
A
M
D
A
L
S
Q
E
V
M
A
RPEA
D
S
V
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
--
A
A
L
R
Q
L
D
A
A
L
A
D
T
D
N
L
K
R
Q
-
L
P
S
E
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
G
A
D
I
V
K
R
S
D
A
L
Y
Q
I
Q
L
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.58
26%
94
- C1 -
-
5SZK
-
A:
[85-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
D
H
Q
S
R
L
E
---------
Q
K
L
R
E
K
M
L
K
E
E
S
Q
K
D
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
M
Q
V
I
---
E
Q
R
D
K
L
V
-------
D
S
L
E
E
Q
R
I
R
E
K
---------------------------------
6
PsiBlast_PDB
52.01
26%
99
- C1 -
-
5SZJ
1
B:
[85-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
D
H
Q
S
R
L
E
---------
Q
K
L
R
E
K
M
L
K
E
E
S
Q
K
D
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
M
Q
V
I
---
E
Q
R
D
K
L
V
-------
D
S
L
E
E
Q
R
I
R
E
K
---------------------------------
4
PsiBlast_PDB
51.75
26%
97
- C1 -
-
5SZH
-
A:
[85-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
D
H
Q
S
R
L
E
---------
Q
K
L
R
E
K
M
L
K
E
E
S
Q
K
D
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
M
Q
V
I
---
E
Q
R
D
K
L
V
-------
D
S
L
E
E
Q
R
I
R
E
K
---------------------------------
2
PsiBlast_PDB
47.99
26%
-3
- C1 -
-
3L1C
1
NCD_DROME
A:
[6-89]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
E
V
V
H
----
L
R
---------
Q
R
T
E
E
L
L
R
C
N
E
Q
Q
A
A
E
L
E
T
-----
C
K
E
Q
L
F
Q
S
N
---
M
E
R
K
E
L
H
-------
N
T
V
M
D
L
R
G
N
I
R
V
F
C
R
I
----------------------------
32
Fugue
45.91
10%
58
- C2 -
-
3NA7
1
?
A:
[1-237]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
S
N
T
H
L
K
Q
L
I
E
I
S
H
L
D
K
E
I
D
S
--
L
E
P
L
I
R
E
K
R
K
D
L
D
K
A
L
N
D
K
E
A
K
N
K
A
I
L
N
L
E
E
E
K
L
A
L
K
L
Q
V
S
K
N
E
Q
T
L
Q
D
T
N
A
-----
K
I
A
S
I
Q
K
K
M
S
E
I
K
S
E
R
E
L
R
S
L
N
I
E
E
D
I
A
K
E
R
S
N
Q
A
N
R
E
I
E
N
L
Q
N
E
I
K
R
K
S
E
K
Q
E
D
L
K
K
E
M
L
E
L
E
K
L
A
L
E
L
E
S
L
V
E
N
E
V
K
N
I
K
E
T
Q
Q
I
I
F
K
K
K
E
D
L
V
E
K
T
E
P
K
I
Y
S
F
Y
E
R
I
R
R
W
A
K
N
T
S
I
V
T
I
K
KQACGG
C
F
I
R
L
N
D
K
I
Y
T
E
V
L
T
S
G
D
M
I
T
C
P
Y
C
G
R
I
L
Y
A
E
G
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
42.93
25%
27
- C1 -
-
2NCD
1
A:
[23-85]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
---------
Q
R
T
E
E
L
L
R
C
N
E
Q
Q
A
A
E
L
E
T
-----
C
K
E
Q
L
F
Q
S
N
---
M
E
R
K
E
L
H
-------
N
T
V
M
D
L
R
G
N
I
R
V
F
C
R
I
----------------------------