@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLX1: (2017-11-05 )
MNQNARPHIEKILANLTQLPGVYKMLGKEGELLYVGKAKNLKNRVSSYFVKTIEHPKTQALVARIYDIETLVTRSETEALLLEQNLIKQHRPPYNIMLRDDKSYVYIFVSADKPYPRIASGRGKGKHQIGKFFGPYPSAYSARDTLLVLQKLFNVRQCENSYFSQRKRPCLQYQIKRCSAPCVGLVSPEDYKEDVNNSIRFLQGDTKELNQELIAKMEQAAADLEFEKAVFYRDRLSLLREVQAQQAVFKVKGEADILAITYQAGVTCVQIMHVRNGRMLGGKSYFPDMLGDDLGQMLSDFMANFYFQVADEVPSELIVNTALPDRKELEEALAQQFGKKVQIKSSVRETRAEWLELAEMNVQHAIKGQLSNHLELNERFHQLEQVVGRPIDRIECFDISHTMGEAPIASCVVFDQGGARKRDYRQFAIQDITAGDDYAAMRQALTRRYKKAMLPDLLLIDGGKGQLHMAMEVMQELGLEAFMVGVSKGEGRKPGLETLHFTDGTKIQLPEDSKALHLIQQVRDEAHRFAITKHRAKRDKRRSTSVLEAIPGLGPKRRRDLLTHFGGIQGVLKASEKELTVVPGLGEVMARTIYKILHE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60....----....70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380......--.-390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNQNA
R
P
H
I
E
K
I
L
A
N
L
T
QLP
G
V
Y
K
M
LGKEG
E
L
L
Y
V
GK
A
K
N
L
K
N
R
V
S
S
Y
F
V
K
T
IEHP
K
T
Q
A
L
V
A
R
I
----
Y
D
I
E
T
L
V
TRSE
T
E
A
L
L
L
E
Q
N
L
I
K
QHRPP
Y
N
I
M
L
RDDK
S
Y
V
Y
I
F
V
SADKPYPRIASGRGKG
K
H
Q
I
G
K
F
FGPYPSAYSA
R
D
T
L
L
V
L
Q
K
L
F
N
V
R
Q
C
E
N
S
Y
F
S
Q
RKR
P
C
L
Q
Y
Q
I
K
RCSAP
C
V
GLV
S
P
E
D
Y
K
E
D
V
N
N
S
I
R
FLQG
D
T
K
E
L
N
Q
E
L
I
A
K
M
E
Q
A
A
AD
L
E
F
E
K
A
V
F
Y
R
D
R
L
S
L
L
R
E
V
Q
A
Q
Q
A
V
F
K
VKGEA
D
I
L
A
I
T
YQAG
V
T
C
V
Q
I
M
HVRN
G
R
MLGGKSY
F
P
D
M
L
G
D
D
L
G
Q
M
L
S
D
F
M
A
N
F
Y
F
Q
V
A
D
EV
P
S
E
L
I
VNTALP
D
R
K
E
L
E
E
A
L
A
Q
Q
FGK
K
V
Q
I
K
S
S
V
R
E
T
R
A
E
W
L
E
L
A
E
M
N
V
Q
H
A
I
K
G
Q
L
SN
H
L
E
L
N
E
R
F
H
Q
L
E
Q
V
VG--R-PI
D
R
I
E
C
F
DISHTMGEAP
I
A
S
C
V
V
FDQGGAR
K
R
D
Y
R
Q
F
A
I
Q
DITAG
D
D
Y
A
A
M
R
Q
A
L
T
R
R
Y
K
K
A
MLP
D
L
L
L
I
DGGK
G
Q
L
H
M
A
M
E
V
M
Q
E
LG
L
E
A
F
M
V
GVSKGEGRKPGL
E
T
L
HFTDG
T
K
I
QLPE
D
S
K
A
L
H
L
I
Q
Q
V
R
D
E
A
H
R
F
A
I
T
K
H
R
A
K
R
DKRR
S
T
S
V
L
E
AIPGL
G
P
K
R
R
R
D
L
L
T
H
F
G
G
I
Q
G
V
L
KASEK
E
L
T
VVP
G
L
G
E
V
M
A
R
T
I
Y
K
I
LHE------
4
PsiBlast_PDB
85.46
42%
-126
- C1 -
-
2NRX
1
UVRC_THEMA
A:
[24-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
E
G
I
D
I
S
H
L
Q
G
K
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
-
D
H
P
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
------
E
T
V
V
F
-
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
K
R
R
E
K
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
S
T
E
I
-
A
R
R
V
L
D
I
L
--------
1
PsiBlast_PDB
85.40
42%
-121
- C1 -
-
2NRT
-
A:
[24-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
E
G
I
D
I
S
H
L
Q
G
K
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
-
D
H
P
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
------
E
T
V
V
F
-
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
K
R
R
E
K
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
S
T
E
I
-
A
R
R
V
L
D
I
L
--------
5
PsiBlast_PDB
85.00
42%
-125
- C1 -
-
2NRZ
-
UVRC_THEMA
A:
[24-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
E
G
I
D
I
S
H
L
Q
G
K
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
-
D
H
P
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
------
E
T
V
V
F
-
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
K
R
R
E
K
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
S
T
E
I
-
A
R
R
V
L
D
I
L
--------
2
PsiBlast_PDB
84.82
42%
-116
- C1 -
-
2NRV
-
UVRC_THEMA
A:
[24-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
E
G
I
D
I
S
H
L
Q
G
K
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
-
D
H
P
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
------
E
T
V
V
F
-
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
K
R
R
E
K
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
S
T
E
I
-
A
R
R
V
L
D
I
L
--------
3
PsiBlast_PDB
83.04
42%
-148
- C1 -
-
2NRW
-
UVRC_THEMA
A:
[362-557]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
E
G
I
D
I
S
H
-----
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
----
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
------
E
T
V
V
F
-
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
-----
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
S
T
E
I
-
A
R
R
V
L
D
I
L
--------
52
HHSearch
76.59
40%
29
- C1 -
-
2NRZ
-
UVRC_THEMA
A:
[6-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
A
L
E
E
L
M
K
L
L
N
M-
K
D
F
P
Y
R
I
E
G
I
D
I
S
H
L
Q
G
K
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
E
Q
D
-
H
P
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
K
K
E
E
-----
T
V
V
-
F
E
-
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
H
R
K
R
R
E
K
E
S
L
R
S
V
L
D
N
V
P
G
I
G
P
I
R
K
K
K
L
I
E
H
F
G
S
L
E
N
I
R
S
A
S
L
E
E
I
A
R
V
I
G
-
S
T
E
I
A
R
R
V
L
D
I
L
--------
56
HHSearch
52.07
54%
-86
- C1 -
-
1YD6
-
UVRC_GEOKA
D:
[2-97]
-----
N
E
R
L
K
E
K
L
A
V
L
P
E
Q
P
G
C
Y
L
M
K
D
K
H
G
T
V
I
Y
V
G
K
A
K
S
L
K
E
R
V
R
S
Y
F
T
G
-
T
H
D
G
K
T
Q
R
L
V
E
E
I
----
A
D
F
E
Y
I
V
T
S
S
N
A
E
A
L
I
L
E
M
N
L
I
K
K
H
D
P
K
Y
N
V
M
L
K
D
D
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
51.21
35%
-202
- C1 -
-
1X2I
-
?
A:
[8-63]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
R
L
I
V
E
G
L
P
H
V
S
A
T
L
A
R
R
L
L
K
H
F
G
S
V
E
R
V
F
T
A
S
V
A
E
L
M
K
V
E
G
I
G
E
K
I
A
K
E
I
R
R
V
I
--------
6
PsiBlast_PDB
50.51
58%
-95
- C1 -
-
1YD6
-
UVRC_GEOKA
A:
[9-95]
------------
L
A
V
L
P
E
Q
P
G
C
Y
L
M
K
D
K
H
G
T
V
I
Y
V
G
K
A
K
S
L
K
E
R
V
R
S
Y
F
T
G
T
-
H
D
G
K
T
Q
R
L
V
E
E
I
----
A
D
F
E
Y
I
V
T
S
S
N
A
E
A
L
I
L
E
M
N
L
I
K
K
H
D
P
K
Y
N
V
M
L
K
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
Fugue
50.15
41%
-
- C1 -
-
2NRR
-
UVRC_THEMA
A:
[344-494]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
A
L
E
E
L
M
K
L
L
N
MK
D
-
F
P
Y
R
I
E
G
I
D
I
S
H
L
---
Y
T
V
A
S
L
V
V
F
E
D
G
F
P
K
K
G
D
Y
R
R
Y
K
I
------
D
D
Y
E
S
I
R
T
V
V
K
R
R
Y
S
K
H
P
L
P
N
L
L
F
V
D
G
G
I
G
Q
V
N
A
A
I
E
A
L
K
E
I
G
K
D
C
P
V
V
G
L
A
T
-----------
V
V
F
E
N
R
E
I
H
L
P
H
D
H
P
V
L
R
L
L
V
Q
I
R
D
E
T
H
R
F
A
V
S
Y
------------------------------------------------------------------------
57
HHSearch
49.61
54%
-99
- C1 -
-
1YD6
-
UVRC_GEOKA
B:
[8-95]
-----------
K
L
A
V
L
P
E
Q
P
G
C
Y
L
M
K
D
K
H
G
T
V
I
Y
V
G
K
A
K
S
L
K
E
R
V
R
S
Y
F
T
G
-
T
H
D
G
K
T
Q
R
L
V
E
E
I
----
A
D
F
E
Y
I
V
T
S
S
N
A
E
A
L
I
L
E
M
N
L
I
K
K
H
D
P
K
Y
N
V
M
L
K
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
Fugue
48.30
32%
-180
- C1 -
-
1X2I
-
?
A:
[2-69]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
T
L
A
E
R
Q
R
L
I
V
E
G
L
P
H
V
S
A
T
L
A
R
R
L
L
K
H
F
G
S
V
E
R
V
F
T
A
S
V
A
E
L
M
K
V
E
G
I
G
E
K
I
A
K
E
I
R
R
V
I
T
A
PYIE--
58
HHSearch
47.83
39%
-105
- C1 -
-
1YD3
1
UVRC_THEMA
A:
[1-90]
----
M
K
E
K
I
R
K
K
I
L
L
A
P
E
E
P
G
V
Y
I
F
K
N
K
-
G
V
P
I
Y
I
G
K
A
K
R
L
S
N
R
L
R
S
F
L
N
P
-
Q
-
T
E
K
V
F
R
I
G
E
E
A
----
D
E
L
E
T
I
V
V
M
N
E
R
E
A
F
I
L
E
A
N
L
I
K
K
Y
R
P
K
Y
N
V
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
Fugue
46.89
39%
-93
- C1 -
-
1YD0
1
UVRC_THEMA
A:
[1-89]
----
M
K
E
K
I
R
K
K
I
L
L
A
P
E
E
P
G
V
Y
I
F
K
N
K
-
G
V
P
I
Y
I
G
K
A
K
R
L
S
N
R
L
R
S
Y
L
N
P
--
Q
T
E
K
V
F
R
I
G
E
E
A
----
D
E
L
E
T
I
V
V
M
N
E
R
E
A
F
I
L
E
A
N
L
I
K
K
Y
R
P
K
Y
N
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
Fugue
46.84
28%
-189
- C1 -
-
2A1J
-
A:
[2-63]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
D
F
L
L
K
M
P
G
V
N
A
K
N
C
R
S
L
M
H
H
V
K
N
I
A
E
L
A
A
L
S
Q
D
E
L
T
S
I
L
G
-
N
A
A
N
A
K
Q
L
Y
D
F
I
H
T
SFAEVV
19
PsiBlast_PDB
46.75
36%
-181
- C1 -
-
2BHN
-
?
A:
[173-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
Q
S
F
P
G
I
G
R
R
T
A
E
R
I
L
E
R
F
G
S
L
E
R
F
F
T
A
S
K
A
E
I
S
K
V
E
G
I
G
E
K
R
A
E
E
I
K
K
I
L
--------
59
HHSearch
46.30
40%
-94
- C1 -
-
1YD0
1
UVRC_THEMA
A:
[1-89]
----
M
K
E
K
I
R
K
K
I
L
L
A
P
E
E
P
G
V
Y
I
F
K
N
K
-
G
V
P
I
Y
I
G
K
A
K
R
L
S
N
R
L
R
S
Y
L
N
P
-
Q
-
T
E
K
V
F
R
I
G
E
E
A
----
D
E
L
E
T
I
V
V
M
N
E
R
E
A
F
I
L
E
A
N
L
I
K
K
Y
R
P
K
Y
N
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
HHSearch
46.15
25%
-178
* C1 *
-
4YVZ
-
DISA_THEMA
B:
[312-368]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
Y
R
L
L
K
T
V
A
R
I
P
L
S
I
G
Y
N
V
V
R
M
F
K
T
L
D
Q
I
S
K
A
S
V
E
D
L
K
K
V
E
G
I
G
E
K
R
A
R
A
I
S
E
S
I
S
-------
17
PsiBlast_PDB
45.96
34%
-176
- C1 -
-
2MUT
-
ERCC1_HUMAN
A:
[234-291]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
T
E
C
L
T
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
T
F
G
S
L
E
Q
L
I
A
A
S
R
E
D
L
A
L
C
P
G
L
G
P
Q
K
A
R
R
L
F
D
V
L
H
E
------
11
PsiBlast_PDB
44.88
43%
-94
- C1 -
-
1YD3
1
UVRC_THEMA
A:
[16-90]
-------------------
P
G
V
Y
-
I
F
K
N
K
G
V
P
I
Y
I
G
K
A
K
R
L
S
N
R
L
R
S
F
L
-----
N
P
Q
T
E
K
-
V
F
R
I
G
E
E
A
D
E
L
E
T
I
V
V
M
N
E
R
E
A
F
I
L
E
A
N
L
I
K
K
Y
R
P
K
Y
N
V
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------