@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VM26: (2017-11-05 )
MKASLRLRLDQLCDRHEELTALLADAEVISDNKRFRKLSREHSDLTEITEVWGKYRQAEEDIETAEMMKSDPDFKDMAEEEIQANKALLEELESQLNILMIPKDPNDSNAAYLEIRAGTGGDEAAIFSGDLFRMYSKYAESQGWRIEVLSENEGEHGGFKEVICRVDGDGVYGRLKFESGAHRVQRVPATESQGRVHTSACTVAILPEIDVDTNVEINPADLRIDTYRASGAGGQHINKTDSAVRITHIPTGTVVECQEERSQHKNKAKAMALLVSRLENAKRAAADAATSEMRRDLVGSGDRSERIRTYNYPQGRMTDHRINLTLYKLDAIMEGDLTELLDSLHREYQADQLAMLAQENGG
Atome Classification :
(20 SA)
--------.........10......-----..20........30........40........50........60........---70-........80........90........100.......110.......120.....-..130.......140.......150.......160.--......170.......180.......190.......200.......210.......220.......230.......240.------...--------------------.---------------------.------.250----------------.-----------------.------------------.-------------------------..-....260.......270.....---.---.280.......290.......300.......310.......320.......330.......340.......350.......360
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------MKA
S
L
R
L
R
L
D
Q
L
C
D
R
H
E
-----
E
L
T
A
L
L
A
D
A
E
VISD
N
K
R
F
R
K
L
S
R
EHS
D
L
T
E
I
T
E
V
W
G
K
Y
R
Q
A
E
E
D
I
E
T
A
E
M
MK---SD-P
D
F
K
D
M
A
E
E
E
I
Q
A
N
K
A
L
L
E
E
L
E
SQL
N
I
L
M
IPKDPNDSN
A
A
Y
L
E
I
R
AGTGGDE
A
A
I
F-S
G
D
L
F
R
M
Y
S
K
Y
AESQG
W
R
I
E
V
L
SENEGEHG
G
F
K
E
V
I
--
C
R
VDGDG
V
Y
G
R
L
K
FESGAH
R
V
Q
RVPATESQG
R
V
H
T
S
A
C
T
V
A
I
L
PEIDVDTN
V
E
INPA
D
L
R
I
D
T
Y
RASGAGGQHINKTD
S
A
------
V
R
I
--------------------
T
---------------------H------IP------------------T-----------------G------------------
T
-------------------------
V
V
-
E
C
Q
E
E
R
S
Q
H
K
N
K
A
K
A
M
A
L
L
V
S
R
---
L
---
E
N
A
K
R
AAAD
A
A
T
S
E
M
R
R
D
LVGSGDRS
E
R
I
R
TYNYPQGRMTD
H
R
I
N
L
T
L
Y
K
L
D
A
I
MEG
D
L
T
E
L
L
D
S
L
H
R
E
Y
Q
A
D
Q
L
A
M
L
A
QENGG
17
HHSearch
94.08
51%
-62
- C6 -
-
1ZBT
-
RF1_STRMU
A:
[3-358]
------------
I
Y
D
Q
L
Q
A
V
E
D
R
Y
E
-----
E
L
--------------------
R
E
E
A
N
S
R
E
T
V
A
V
Y
R
E
Y
K
Q
V
V
Q
N
I
A
D
A
Q
E
M
-------
P
E
L
E
E
M
A
K
E
E
L
K
N
S
K
V
A
K
E
E
Y
E
E
K
L
R
F
L
L
L
P
K
D
P
N
D
D
K
N
I
I
L
E
I
R
G
A
A
G
G
D
E
A
A
L
F
-
A
G
D
L
L
N
M
Y
Q
K
Y
A
E
N
Q
G
W
K
F
E
V
M
E
A
S
A
N
G
V
G
G
L
K
E
V
V
--
A
M
V
S
G
Q
S
V
Y
S
K
L
K
Y
E
S
G
A
H
R
V
Q
R
V
P
V
T
E
S
Q
G
R
V
H
T
S
T
A
T
V
L
V
M
P
E
V
E
E
-
V
E
Y
E
I
D
P
K
D
L
R
V
D
I
Y
H
A
---------
K
V
A
T
A
------
V
R
I
--------------------
I
---------------------
H
------
L
P
------------------
T
-----------------
N
------------------
I
-------------------------
K
V
-
E
M
Q
E
E
R
T
Q
Q
K
N
R
D
K
A
M
K
I
I
R
A
R
---
V
---
A
D
H
F
A
Q
I
A
Q
D
E
Q
D
A
----
T
V
G
T
G
D
R
S
E
R
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
G
L
T
L
Q
K
L
D
S
I
L
S
G
K
L
D
E
V
I
D
A
L
I
L
Y
D
Q
T
Q
K
L
E
E
L
N
-----
1
PsiBlast_PDB
88.50
60%
-65
- C6 -
-
2B3T
-
RF1_ECOLI
B:
[7-354]
--------------
A
K
L
E
A
L
H
E
R
H
E
-----
E
V
Q
A
L
L
G
D
A
Q
T
I
A
D
Q
E
R
F
R
A
L
S
R
E
Y
A
Q
L
S
D
V
S
R
C
F
T
D
W
Q
Q
V
---------------------------------------
Q
Q
L
Q
V
L
L
L
P
K
D
P
D
D
E
R
N
A
F
L
E
V
R
A
G
T
G
G
D
E
A
A
L
F
-
A
G
D
L
F
R
M
Y
S
R
Y
A
E
A
R
R
W
R
V
E
I
M
S
A
S
E
G
E
H
G
G
Y
K
E
I
I
--
A
K
I
S
G
D
G
V
Y
G
R
L
K
F
E
S
G
G
H
R
V
Q
R
V
P
A
T
E
S
Q
G
R
I
H
T
S
A
C
T
V
A
V
M
P
E
L
P
D
A
E
L
P
D
V
N
P
A
D
L
R
I
D
T
F
R
S
S
G
A
G
G
Q
H
V
N
T
T
D
S
A
------
I
R
I
--------------------
T
---------------------
H
------
L
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
V
-
E
C
Q
D
E
R
S
Q
H
K
N
K
A
K
A
L
S
V
L
G
A
R
---
I
---
H
A
A
E
M
A
K
R
Q
------
R
R
N
-------
S
D
R
N
R
T
Y
N
F
P
Q
G
R
V
T
D
H
R
I
N
L
T
L
Y
R
L
D
E
V
M
E
G
K
L
D
M
L
I
E
P
I
I
Q
E
H
Q
A
D
Q
L
A
--------
24
HHSearch
82.55
45%
-50
- C6 -
-
1RQ0
-
C:
[801-1133]
-------------------
M
K
E
K
K
K
-----
E
I
E
K
L
L
A
R
P
D
L
T
P
E
--
Q
M
K
N
Y
G
M
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
I
K
E
T
Q
E
F
I
----
E
L
L
---
R
E
-
E
---
G
E
N
E
L
E
I
E
K
Y
E
K
E
L
D
Q
L
Y
Q
E
L
L
F
L
L
---
S
P
E
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
-
A
R
D
L
F
R
M
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
--
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
L
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
V
-
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
L
R
I
L
R
A
R
---
L
---
Y
Q
L
Q
K
E
Q
K
E
R
E
I
S
Q
----------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
E
V
L
-----
5
PsiBlast_PDB
78.82
38%
0
- C- -
-
1ML5
-
RF2_ECOLI
Z:
[25-359]
--------------
L
D
Y
D
A
K
K
E
R
L
E
-----
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
---
V
E
-
A
D
D
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
-
A
Q
L
E
F
R
R
M
F
S
G
E
Y
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
-
A
S
M
L
E
R
M
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
--
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
E
I
N
P
A
D
L
R
I
D
V
Y
R
T
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
I
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
T
-
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
M
K
Q
M
K
A
K
LYE
L
---
E
M
Q
K
K
N
A
E
K
Q
A
M
E
D
N
K
S
D
-
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
-------------------
6
PsiBlast_PDB
77.25
38%
-14
- C6 -
-
1GQE
-
RF2_ECOLI
A:
[25-359]
--------------
L
D
Y
D
A
K
K
E
R
L
E
-----
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
---
V
E
-
A
D
D
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
-
A
Q
L
E
F
R
R
M
F
S
G
E
Y
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
-
A
S
M
L
E
R
M
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
--
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
I
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
T
-
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
M
K
Q
M
K
A
K
---
L
Y
E
V
E
M
Q
K
K
N
A
E
K
Q
A
M
E
D
N
K
S
D
-
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
-------------------
3
PsiBlast_PDB
76.53
48%
-40
- C6 -
-
1RQ0
-
RF1_THEMA
A:
[28-320]
-----------------------------------------------------
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
I
K
E
T
Q
E
F
I
E
L
L
R
E
E
G
---
E
N
-
E
L
E
I
E
K
Y
E
K
E
-------
L
D
Q
L
Y
Q
E
L
L
F
L
L
---
S
P
E
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
-
A
R
D
L
F
R
M
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
--
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
-
E
K
D
I
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
----
Y
V
N
K
T
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
L
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
V
-
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
L
R
I
L
R
A
R
---
L
---
Y
Q
L
Q
K
E
Q
K
E
R
E
I
S
Q
----------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
------------------
23
HHSearch
74.01
46%
-
- C6 -
-
2FVO
-
RF1_THEMA
A:
[1-331]
-------------------
M
K
E
K
K
K
-----
E
I
E
K
L
L
A
R
P
D
L
T
P
E
--
Q
M
K
N
Y
G
M
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
I
K
E
T
Q
E
F
I
E
L
L
R
E
E
----
G
E
-
N
------
E
L
E
I
E
K
Y
E
K
E
L
D
Q
L
Y
Q
E
L
L
F
L
L
---
S
P
E
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
-
A
R
D
L
F
R
M
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
--
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
L
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
V
-
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
L
R
I
L
R
A
R
---
L
---
Y
Q
L
Q
K
E
Q
K
E
R
E
I
S
Q
----------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
E
-------
20
HHSearch
70.37
38%
47
- C6 -
-
1GQE
-
RF2_ECOLI
A:
[27-362]
----------------
Y
D
A
K
K
E
R
L
E
-----
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
D
-
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
A
Q
L
E
F
----
R
R
M
F
S
G
E
Y
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
-
A
S
M
L
E
R
M
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
--
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
I
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
T
-
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
M
K
Q
M
K
A
K
---
L
---
Y
E
V
E
M
Q
K
K
N
A
E
K
Q
A
M
E
-
D
N
K
S
D
I
G
W
G
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
S
L
K
----------------
4
PsiBlast_PDB
69.02
39%
-
- C6 -
-
1MI6
-
RF2_ECOLI
A:
[25-359]
--------------
L
D
Y
D
A
K
K
E
R
L
E
-----
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
---
V
E
-
A
D
D
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
-
A
Q
L
E
F
R
R
M
F
S
G
E
Y
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
-
A
S
M
L
E
R
M
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
--
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
I
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
T
-
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
M
K
Q
M
K
A
K
---
L
Y
E
V
E
M
Q
K
K
N
A
E
K
Q
A
M
E
D
N
K
S
D
-
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
-------------------
2
PsiBlast_PDB
66.14
48%
-
- C6 -
-
2FVO
-
RF1_THEMA
A:
[28-320]
-----------------------------------------------------
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
I
K
E
T
Q
E
F
I
E
L
L
R
E
E
G
---
E
N
-
E
L
E
I
E
K
Y
E
K
E
-------
L
D
Q
L
Y
Q
E
L
L
F
L
L
---
S
P
E
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
-
A
R
D
L
F
R
M
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
--
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
-
E
K
D
I
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
------
V
R
I
--------------------
T
---------------------
H
------
L
P
------------------
T
-----------------
G
------------------
I
-------------------------
V
V
-
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
L
R
I
L
R
A
R
---
L
---
Y
Q
L
Q
K
E
Q
K
E
R
E
I
S
Q
----------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
------------------
30
HHSearch
47.62
39%
-35
- C6 -
-
2JY9
-
?
A:
[7-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
S
I
A
D
N
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
S
A
------
I
H
L
--------------------
R
F
D
IRA
S
G
L
P
E
Y
Y
K
Q
R
L
L
T
ASH
H
------
L
I
------------------
S
DDG--------------
V
------------------
I
-------------------------
I
I
-
K
A
Q
E
F
R
S
Q
E
L
N
R
E
A
A
I
A
R
L
V
A
V
---
I
---
K
E
L
T
A
E
Q
-----------------------------------------------------------------------------
28
HHSearch
47.06
37%
-40
- C6 -
-
2JVA
-
?
A:
[7-100]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
H
L
P
D
A
E
I
E
L
T
A
I
R
A
Q
G
A
G
G
Q
N
V
N
K
V
S
S
A
------
M
H
L
--------------------
R
---------------------
F
DINASS
L
P
P
F
Y
K
E
R
L
L
A
LNDSRITS-
D
-----------------
G
V
-----------------
I
-------------------------
V
L
-
K
A
Q
Q
Y
R
T
Q
E
Q
N
R
A
D
A
L
L
R
L
S
E
L
---
I
---
V
N
A
A
K
-------------------------------------------------------------------------------
7
PsiBlast_PDB
46.21
30%
-60
- C6 -
-
2RSM
-
CL065_MOUSE
A:
[12-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
Q
E
K
P
A
L
L
F
P
G
---
M
A
A
S
T
V
Q
V
A
G
R
K
D
Y
P
A
L
L
P
L
N
E
S
E
L
E
E
Q
F
V
K
G
H
G
P
G
G
Q
A
T
N
K
T
S
N
C
------
V
V
L
--------------------
K
---------------------
H
------
V
P
------------------
S
-----------------
G
------------------
I
-------------------------
V
V
-
K
C
H
Q
T
R
S
V
D
Q
N
R
K
I
A
R
K
V
L
Q
E
K
---
V
---
D
-----------------------------------------------------------------------------------
26
HHSearch
45.34
26%
-48
- C6 -
-
2RSM
-
CL065_MOUSE
A:
[4-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
K
W
G
L
R
L
Q
E
K
P
A
L
L
F
P
-
G
M
A
A
S
T
V
Q
V
A
G
R
K
D
Y
P
A
--
L
L
P
L
N
E
S
E
L
E
E
Q
F
V
K
G
H
G
P
G
G
Q
A
T
N
K
T
S
N
C
------
V
V
L
--------------------
K
---------------------
H
------
V
P
------------------
S
-----------------
G
------------------
I
-------------------------
V
V
-
K
C
H
Q
T
R
S
V
D
Q
N
R
K
I
A
R
K
V
L
Q
E
K
---
V
---
D
V
F
Y
N
S
G
-----------------------------------------------------------------------------
29
HHSearch
44.56
39%
-39
- C6 -
-
2RTX
-
ARFB_ECOLI
A:
[7-102]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
V
A
I
P
D
G
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
T
A
------
I
H
L
--------------------
R
F
DIRAS---------------
S
------
L
P
E
Y
Y
K
E
R
L
L
A
ASHHLISSD
G
-----------------
V
------------------
I
-------------------------
V
I
-
K
A
Q
E
Y
R
S
Q
E
L
N
R
E
A
A
L
A
R
L
V
A
M
---
I
---
K
E
L
T
T
E
K
-----------------------------------------------------------------------------
41
Fugue
43.22
21%
48
* C5 *
-
1DMU
2
T2B1_BACIU
A:
[1-299]
MYNLH
R
E
K
I
F
M
S
Y
N
Q
N
K
Q
Y
L
E
D
N
P
E
I
Q
E
K
I
E
L
Y
G
L
N
L
L
N
E
V
I
S
D
N
--
E
E
E
I
R
A
D
Y
N
E
A
N
F
L
H
P
F
W
M
N
Y
P
P
----
L
D
R
G
K
M
P
K
---
G
D
Q
I
P
W
I
E
V
G
E
K
A
V
--
G
S
K
L
T
R
L
V
S
Q
R
E
D
I
T
V
R
------------
E
I
G
L
P
T
G
P
D
E
R
Y
L
L
T
S
P
T
I
Y
S
L
T
N
G
F
T
D
S
I
M
M
F
V
D
I
K
S
V
G
P
-
R
D
S
D
Y
D
L
V
L
S
P
N
Q
V
S
G
N
G
D
W
A
Q
L
E
G
G
I
Q
N
N
Q
Q
T
I
Q
G
P
R
S
S
Q
I
F
L
P
T
-------
I
P
P
L
Y
I
L
S
D
G
T
I
A
P
V
---
V
H
L
F
I
K
P
I
Y
A
M
R
S
L
T
K
G
D
T
G
------
Q
S
L
--------------------
Y
---------------------
K
------
I
K
------------------
L
-----------------
A
------------------
S
-------------------------
V
P
-
N
-------------
G
L
G
L
F
C
N
-----------
P
G
Y
A
F
D
S
A
Y
K
F
L
F
R
P
--
G
K
D
D
R
T
K
S
----------
L
L
Q
K
R
V
R
V
D
L
R
V
L
D
K
I
G
P
R
V
M
T
I
D
M
D
K
-------------------
10
PsiBlast_PDB
43.13
26%
-27
- C6 -
-
2JVA
-
?
A:
[4-100]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
N
N
V
H
L
P
D
A
E
I
E
L
T
A
I
R
A
Q
G
A
G
G
Q
N
V
N
K
V
S
S
A
------
M
H
L
R
F
DINA--------------
S
---------------------
S
------
L
P
------------------
P
F
Y
K
E
R
L
L
A
LNDSRITSD
G
------------------
V
-------------------------
I
V
L
K
A
Q
Q
Y
R
T
Q
E
Q
N
R
A
D
A
L
L
R
L
S
E
L
---
I
---
V
N
A
A
K
-------------------------------------------------------------------------------
8
PsiBlast_PDB
41.58
31%
-47
- C6 -
-
2RTX
-
ARFB_ECOLI
A:
[2-96]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
I
S
R
H
V
A
I
P
D
G
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
T
A
I
H
L
R
F
D
I
R
A
--------------------
S
---------------------
S
------
L
P
------------------
E
-----------------
Y
Y
K
E
R
L
L
A
ASHHLISSDG
V
I
-------------------------
V
I
-
K
A
Q
E
Y
R
S
Q
E
L
N
R
E
A
A
L
A
R
L
V
A
M
---
I
---
K
-----------------------------------------------------------------------------------
32
HHSearch
35.19
29%
38
- C6 -
-
1J26
-
ICT1_MOUSE
A:
[14-107]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
Y
I
P
L
D
R
L
S
I
S
Y
C
R
S
S
G
P
G
G
Q
N
V
N
K
V
N
S
K
------
A
E
V
R
F
HLASADWIE
E
P
V
R
Q
K
I
A
L
T
---------------------
H
------
K
N
KINKA-------------
G
-----------------
E
------------------
L
-------------------------
V
L
-
T
S
E
S
S
R
Y
Q
F
R
N
L
A
E
C
L
Q
K
I
R
D
M
---
I
---
A
E
A
S
--------------------------------------------------------------------------------
39
Fugue
34.56
21%
28
- C6 -
-
1J26
-
ICT1_MOUSE
A:
[1-112]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
S
S
G
E
H
A
K
Q
A
S
S
Y
I
P
L
D
R
L
S
I
S
Y
C
R
S
S
G
P
G
G
Q
N
V
N
K
V
N
S
K
------
A
E
V
--------------------
R
---------------------
F
------
H
L
------------------
A
-----------------
S
------------------
A
DWIE
E
P
V
R
Q
K
I
A
L
T
HKNKINKAG
E
L
V
L
-
T
S
E
S
S
R
Y
Q
F
R
N
L
A
E
C
L
Q
K
I
R
D
M
---
I
---
A
E
A
S
G
P
S
S
G
---------------------------------------------------------------------------