@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMA6: (2017-11-07 )
MAKAKFERNKPHVNVGTIGHVDHGKTTLTAAIATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPGDDTPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLLDEGRAGENCGILLRGTKREEVQRGQVLAKPGTIKPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPGLRFAIREGGRTVGAGVVAKVTA
Atome Classification :
(53 SA)
.........10........20........30..--..-..-..-40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......----180..--------.....----.190.......200.......210.......220.......230.......240.......250-........260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MAKAKFERNKPHVNV
G
T
I
GHVDHG
K
T
T
L
T
A
A
I
A
--
T
I
-
C
A
-
K
T-YGGEAK
D
Y
S
QIDSA
P
E
EKAR
G
I
T
I
NT
S
H
V
EYDSPT
R
H
Y
A
HVDCPG
H
A
D
Y
V
K
N
M
I
TGAAQMD
G
A
I
L
V
C
AATDGPMPQ
T
R
E
H
I
L
L
SRQVGV
P
Y
I
I
V
F
LNKCDLV
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
TYDFPGDDT
P
V
IRG
S
A
L
A
AL----NG-EA--------GPY
G
E
----
E
S
V
L
A
L
V
A
A
L
D
S
YIP
E
P
E
R
A
I
D
K
A
F
L
M
P
I
E
D
V
FSISGR
G
T
V
V
TGRV
E
A
G
I
I
KVG
E
E
V
E
I
V
GI-K-
D
T
V
K
T
T
V
T
G
V
E
M
F
R
K
L
L
DEGRAGEN
C
G
I
L
L
RGT
K
R
E
E
V
QRG
Q
V
LAKPGTIKPHTKFD
A
E
V
Y
V
L
SKEEGGRHTPFLNGYR
P
Q
F
Y
F
R
TTDV
T
G
A
I
Q
LKEG
V
E
M
VMPGDN
V
E
M
S
V
E
L
I
H
P
IAMDPG
L
R
F
A
I
REGGRTVGA
G
V
V
A
K
VTA
35
PsiBlast_CBE
95.27
84%
-99
- C1 -
-
1D8T
1
EFTU1_ECOLI
A:
[3-391]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
12
PsiBlast_PDB
95.20
85%
-101
- C1 -
-
5JBQ
1
?
A:
[3-392]
--
K
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
23
PsiBlast_CBE
94.42
84%
-99
- C1 -
-
1DG1
1
EFTU2_ECOLI
H:
[10-394]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
4
PsiBlast_PDB
94.13
85%
-97
- C1 -
-
4G5G
1
EFTU1_ECOLI
A:
[4-392]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
5
PsiBlast_PDB
93.95
84%
-104
- C1 -
-
1DG1
1
EFTU2_ECOLI
G:
[10-394]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
14
PsiBlast_PDB
93.90
84%
-100
- C1 -
-
1EFC
1
EFTU1_ECOLI
A:
[8-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
2
PsiBlast_PDB
93.80
85%
-102
- C1 -
-
3U6K
1
EFTU1_ECOLI
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
22
PsiBlast_CBE
93.15
85%
-99
- C1 -
-
3U6K
1
?
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
29
PsiBlast_CBE
92.83
84%
-95
- C1 -
-
1EFC
1
EFTU1_ECOLI
B:
[8-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
34
PsiBlast_CBE
92.76
84%
-105
- C1 -
-
1D8T
2
EFTU1_ECOLI
B:
[9-391]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
3
PsiBlast_PDB
92.09
85%
-104
- C1 -
-
3U2Q
1
?
A:
[7-392]
------
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
---
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
32
PsiBlast_CBE
92.07
84%
-98
- C1 -
-
2FX3
1
EFTU1_ECOLI
A:
[7-391]
-------
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
6
PsiBlast_PDB
91.92
85%
-106
- C1 -
-
4P3Y
2
?
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
25
PsiBlast_CBE
91.64
85%
-115
- C1 -
-
4PC3
2
EFTU1_ECOLI
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
--------------
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
26
PsiBlast_CBE
91.53
85%
-113
- C1 -
-
4PC2
1
?
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
----------
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
24
PsiBlast_CBE
90.72
85%
-114
- C1 -
-
4PC6
2
?
B:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
--------------
K
A
R
G
I
----
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
8
PsiBlast_PDB
90.07
85%
-118
- C1 -
-
4PC2
1
?
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-----------------------
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
9
PsiBlast_PDB
89.82
85%
-119
- C1 -
-
4PC3
1
EFTU1_ECOLI
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-----------------------
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
7
PsiBlast_PDB
89.67
85%
-118
- C1 -
-
4PC1
1
?
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-----------------------
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
10
PsiBlast_PDB
89.23
85%
-115
- C1 -
-
4PC6
2
?
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-----------------------
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
13
PsiBlast_PDB
89.19
84%
-94
- C1 -
-
1OB2
3
EFTU2_ECOLI
A:
[1-393]
-
A
K
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
A
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
17
PsiBlast_PDB
89.00
84%
-102
- C1 -
-
2BVN
2
EFTU2_ECOLI
A:
[9-393]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-------------
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
S
64
PsiBlast_CBE
86.41
85%
-123
- C1 -
-
5I4R
1
?
H:
[1-333]
----------------------------------------------------------------
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
65
PsiBlast_CBE
85.95
85%
-122
- C1 -
-
5I4R
1
?
D:
[1-333]
----------------------------------------------------------------
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
72
PsiBlast_CBE
85.53
85%
-115
- C1 -
-
2HCJ
3
EFTU1_ECOUT
B:
[1-333]
----------------------------------------------------------------
G
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
11
PsiBlast_PDB
85.14
85%
-108
- C1 -
-
4PC7
2
EFTU1_ECOLI
A:
[9-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-------------------
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
--
119
HHSearch
84.33
85%
-119
- C1 -
-
2HCJ
3
EFTU1_ECOUT
B:
[11-334]
--------------------------------------------------------------------------
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
----------
A
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
G
I
-
K
-
E
T
Q
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
R
G
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
S
E
V
Y
I
L
S
K
D
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
V
L
-
1
PsiBlast_PDB
81.32
82%
-44
- C1 -
-
4ZV4
1
EFTU_PSEAE
A:
[8-395]
-------
R
N
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
K
V
-
C
S
-
D
T
-
W
G
G
S
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
S
A
V
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
M
V
D
D
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
N
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
L
M
A
L
----
E
G
K
D
D
--------
N
G
I
G
V
----
S
A
V
Q
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
Q
E
E
V
E
I
V
G
I
-
K
-
A
T
T
K
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
I
L
L
R
G
T
K
R
E
D
V
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
C
E
V
Y
V
L
S
K
E
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
A
P
I
A
M
E
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
I
--
21
PsiBlast_CBE
80.58
82%
-42
- C1 -
-
4ZV4
1
EFTU_PSEAE
B:
[10-395]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
K
V
-
C
S
-
D
T
-
W
G
G
S
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
S
A
V
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
M
V
D
D
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
N
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
L
M
A
L
----
E
G
K
D
D
--------
N
G
I
G
V
----
S
A
V
Q
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
V
E
R
G
I
I
K
V
Q
E
E
V
E
I
V
G
I
-
K
-
A
T
T
K
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
I
L
L
R
G
T
K
R
E
D
V
E
R
G
Q
V
L
A
K
P
G
T
I
K
P
H
T
K
F
E
C
E
V
Y
V
L
S
K
E
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
A
P
I
A
M
E
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
I
--
40
PsiBlast_CBE
78.97
77%
-49
- C1 -
-
4IW3
2
EFTU1_PSEPK
B:
[46-431]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
R
V
-
C
S
-
E
V
-
F
G
S
------
K
I
D
S
A
P
E
E
K
A
R
G
I
T
I
N
T
A
H
V
E
Y
N
S
T
I
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
--
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
L
----
E
G
K
D
D
--------
N
E
M
G
T
----
T
A
V
K
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
G
L
-
R
-
D
T
T
T
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
R
G
T
K
R
D
D
V
E
R
G
Q
V
L
V
K
P
G
S
V
K
P
H
T
K
F
T
A
E
V
Y
V
L
S
K
E
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
I
--
39
PsiBlast_CBE
78.47
77%
-43
- C1 -
-
4IW3
2
EFTU1_PSEPK
K:
[46-431]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
R
V
-
C
S
-
E
V
-
F
G
-------
K
I
D
S
A
P
E
E
K
A
-
G
I
T
I
N
T
A
H
V
E
Y
N
S
T
I
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
--
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
L
----
E
G
K
D
D
--------
N
E
M
G
T
----
T
A
V
K
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
R
G
T
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
G
L
-
R
-
D
T
T
T
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
R
G
T
K
R
D
D
V
E
R
G
Q
V
L
V
K
P
G
S
V
K
P
H
T
K
F
T
A
E
V
Y
V
L
S
K
E
E
G
G
R
H
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
A
K
I
--
108
HHSearch
70.99
71%
9
- C1 -
-
2C78
2
EFTU1_THET8
A:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
-
A
E
N
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
----
E
Q
-
M
H
R
NPKTRRG
E
N
E
W
V
----
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
A
P
-
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
L
E
47
PsiBlast_CBE
70.72
70%
16
- C1 -
-
1EXM
1
EFTU1_THETH
A:
[3-403]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
F
V
T
A
A
-
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
53
PsiBlast_CBE
70.70
70%
19
- C1 -
-
4LBV
1
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
43
PsiBlast_CBE
70.70
70%
11
- C1 -
-
2C78
2
EFTU1_THET8
A:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
50
PsiBlast_CBE
70.61
70%
20
- C1 -
-
4LBZ
1
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
42
PsiBlast_CBE
70.55
70%
22
- C1 -
-
4H9G
2
EFTU1_THETH
A:
[2-403]
--
K
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
52
PsiBlast_CBE
70.29
70%
19
- C1 -
-
4LBW
1
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
49
PsiBlast_CBE
70.28
70%
21
- C1 -
-
4LC0
1
EFTU1_THETH
A:
[2-402]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
51
PsiBlast_CBE
70.26
70%
19
- C1 -
-
4LBY
1
EFTU1_THETH
A:
[4-402]
-----
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
48
PsiBlast_CBE
70.05
69%
18
- C1 -
-
1EFT
1
EFTU_THEAQ
A:
[1-403]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
F
V
T
A
A
-
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
M
H
K
N
-
P
K
--------
T
K
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
63
PsiBlast_CBE
69.95
69%
16
- C1 -
-
1B23
2
EFTU_THEAQ
P:
[1-403]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
EEMH
K
N
-
P
K
--------
T
K
R
G
E
NEWV
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
I
L
K
K
E
E
G
G
R
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
54
PsiBlast_CBE
69.75
69%
15
- C1 -
-
1TUI
1
EFTU_THEAQ
C:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
EEMH
K
N
-
P
K
--------
T
K
R
G
E
NEWV
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
I
L
K
K
E
E
G
G
R
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
56
PsiBlast_CBE
69.73
69%
14
- C1 -
-
1TUI
1
EFTU_THEAQ
A:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
M
H
K
N
-
P
K
--------
T
K
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
I
L
K
K
E
E
G
G
R
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
44
PsiBlast_CBE
69.72
70%
18
- C1 -
-
2C77
2
EFTU2_THET8
A:
[2-403]
--
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
T
A
A
-
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
55
PsiBlast_CBE
69.18
69%
16
- C1 -
-
1TUI
1
EFTU_THEAQ
B:
[9-403]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
Y
V
-
A
A
A
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
EEMH
K
N
-
P
K
--------
T
K
R
G
E
NEWV
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
I
L
K
K
E
E
G
G
R
H
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
46
PsiBlast_CBE
67.36
70%
19
- C1 -
-
1HA3
4
EFTU1_THET8
A:
[3-403]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
--
F
V
T
A
A
-
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
------------
T
A
H
V
E
Y
E
T
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
M
H
R
N
-
P
K
--------
T
R
R
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
R
G
T
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
G
L
-
A
P
E
T
R
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
R
G
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
I
T
P
H
T
K
F
E
A
S
V
Y
V
L
K
K
E
E
G
G
R
H
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
G
R
T
V
G
A
G
V
V
T
K
I
--
33
PsiBlast_CBE
53.09
84%
-141
- C1 -
-
1ETU
1
EFTU1_ECOLI
A:
[5-200]
-----
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
-------------------
I
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
31.64
82%
-
- C1 -
-
1EFM
1
EFTU2_ECOLI
A:
[12-175]
------------
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
---------------------
T
I
N
T
S
H
V
E
Y
D
T
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
----
E
G
-
D
A
----------
E
W
E
----
A
K
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
PsiBlast_CBE
18.80
34%
-10
- C1 -
-
3J25
1
TET1_ENTFL
A:
[3-130]
------------
I
N
I
G
V
L
A
H
V
D
A
G
K
T
T
L
T
E
S
L
L
Y
N
S
G
-
A
I
-
T
E
-
L
G
S
V
D
K
G
T
T
R
T
D
N
T
L
L
E
R
Q
R
G
I
T
I
Q
T
G
I
T
S
F
Q
W
E
N
T
K
V
N
I
I
D
T
P
G
H
M
D
F
L
A
E
V
Y
R
S
L
S
V
L
D
G
A
I
L
L
I
S
A
K
D
G
V
Q
A
Q
T
R
I
L
F
H
A
L
R
K
M
G
I
P
-
T
I
F
F
I
N
K
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101
PsiBlast_CBE
7.09
82%
25
- C1 -
-
5I4R
1
?
C:
[9-42]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
6.80
82%
23
- C1 -
-
5I4R
1
?
G:
[10-42]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
--
T
V
-
L
A
-
K
T
-
Y
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
141
Fugue
5.32
62%
86
- C1 -
-
2P8W
1
S:
[1-35]
------------------------------------
T
-
A
A
-
E
N
-
P
N
V
E
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------