@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMC9: (2017-11-07 )
MSPSNPVLSHHISSQFNEDLQDVNTKFMTMGGLVEQQVANAIHSLLDTDANLAIDVQFKDNAVNQYERDIDEGLTLILARRHPAAIDLRMVIAMSKANTDLERIGDEAAKIARIAQNLCEEGGSPRGYMETRHIGNQVRVMIHDALDAFARLDADQALRVLLADVDIDREYQSATRTLMTYMIEDPRHIARVINVMWVLRSLERIGDHARNIAEQVIYMAKGFDARHTKIEEIEAKVHEK
Atome Classification :
(20 SA)
------------------------------------------------------------------------.........10...-.....20---.........30........40.......-------.----50........60........70........80........90........100.......110.......120........130....----------....140-..-----.......150-------..----......160.......170.......180------..---.....190.......200.....---..210.......220.......230.......240---------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------MSPSN
P
V
L
S
H
H
I
S
S
-
Q
F
N
E
D
L
----
Q
D
V
N
T
K
F
M
T
M
G
G
L
V
E
Q
Q
V
A
N
A
I
H
S
L
LDT-------D----A
N
L
A
I
D
V
Q
FKDNA
V
N
Q
Y
E
R
D
I
D
E
G
L
T
L
I
L
ARRHPA
A
I
D
L
R
M
V
I
A
MSKAN
T
D
L
E
R
I
G
D
E
A
A
K
I
A
R
I
A
Q
N
L
C
EE-GGSPRG
Y
M
E
-
T
R
HIG----------
N
Q
V
R
V
---
M
I
-----
H
D
A
L
D
A
F
A
R--------L
D
----
A
D
Q
A
L
R
V
L
L
ADVDI
D
R
E
Y
Q
S
A
T
R
T
L
M
T
Y
M
------IE---D
P
R
H
I
A
R
V
I
N
V
M
W
V
L
R
S
L
E
R
I
G
D
---
H
A
R
N
I
A
E
Q
V
I
Y
M
AKGFDARH
T
K
I
E
E
I
E
A
K
VHEK-----------------
10
HHSearch
81.13
60%
-105
- C4 -
-
4Q25
-
PHOU_PSEAE
A:
[12-222]
------------------------------------------------------------------------------------
S
Q
-
Q
F
N
A
E
L
----
E
D
V
R
S
H
L
L
A
M
G
G
L
V
E
K
Q
V
N
D
A
V
N
A
L
I
D
A
-------
D
----
S
G
L
A
Q
Q
V
R
E
I
D
D
Q
I
N
Q
M
E
R
N
I
D
E
E
C
V
R
I
L
A
R
R
Q
P
A
A
S
D
L
R
L
I
I
S
I
S
K
S
V
I
D
L
E
R
I
G
D
E
A
S
K
V
A
R
R
A
I
Q
L
C
E
E
-
G
E
S
P
R
G
Y
V
E
-
V
R
H
I
G
----------
S
Q
V
Q
K
---
M
V
-----
Q
E
A
L
D
A
F
A
R
--------
F
D
----
A
D
L
A
L
S
V
A
Q
Y
D
K
T
V
D
R
E
Y
K
T
A
L
R
E
L
V
T
Y
M
------
M
E
---
D
P
R
A
I
S
R
V
L
N
I
I
W
A
L
R
S
L
E
R
I
G
D
---
H
A
R
N
I
A
E
L
V
I
Y
L
V
R
G
T
----------------------------------
1
PsiBlast_PDB
80.78
59%
-105
- C4 -
-
4Q25
-
PHOU_PSEAE
A:
[12-222]
------------------------------------------------------------------------------------
S
Q
-
Q
F
N
A
E
L
----
E
D
V
R
S
H
L
L
A
M
G
G
L
V
E
K
Q
V
N
D
A
V
N
A
L
I
D
A
-------
D
----
S
G
L
A
Q
Q
V
R
E
I
D
D
Q
I
N
Q
M
E
R
N
I
D
E
E
C
V
R
I
L
A
R
R
Q
P
A
A
S
D
L
R
L
I
I
S
I
S
K
S
V
I
D
L
E
R
I
G
D
E
A
S
K
V
A
R
R
A
I
Q
L
C
E
E
-
G
E
S
P
R
G
Y
V
E
-
V
R
H
I
G
----------
S
Q
V
Q
K
---
M
V
-----
Q
E
A
L
D
A
F
A
R
--------
F
D
----
A
D
L
A
L
S
V
A
Q
Y
D
K
T
V
D
R
E
Y
K
T
A
L
R
E
L
V
T
Y
M
------
M
E
---
D
P
R
A
I
S
R
V
L
N
I
I
W
A
L
R
S
L
E
R
I
G
D
---
H
A
R
N
I
A
E
L
V
I
Y
L
V
R
G
T
----------------------------------
9
HHSearch
79.49
60%
-110
- C4 -
-
4Q25
-
PHOU_PSEAE
B:
[14-222]
---------------------------------------------------------------------------------------
Q
F
N
A
E
L
----
E
D
V
R
S
H
L
L
A
M
G
G
L
V
E
K
Q
V
N
D
A
V
N
A
L
I
D
A
-------
D
----
S
G
L
A
Q
Q
V
R
E
I
D
D
Q
I
N
Q
M
E
R
N
I
D
E
E
C
V
R
I
L
A
R
R
Q
P
A
A
S
D
L
R
L
I
I
S
I
S
K
S
V
I
D
L
E
R
I
G
D
E
A
S
K
V
A
R
R
A
I
Q
L
C
E
E
-
G
E
S
P
R
G
Y
V
E
-
V
R
H
I
G
----------
S
Q
V
Q
K
---
M
V
-----
Q
E
A
L
D
A
F
A
R
--------
F
D
----
A
D
L
A
L
S
V
A
Q
Y
D
K
T
V
D
R
E
Y
K
T
A
L
R
E
L
V
T
Y
M
------
M
E
---
D
P
R
A
I
S
R
V
L
N
I
I
W
A
L
R
S
L
E
R
I
G
D
---
H
A
R
N
I
A
E
L
V
I
Y
L
V
R
G
T
----------------------------------
12
HHSearch
65.81
34%
-110
- C4 -
-
1T72
-
PHOU_AQUAE
D:
[6-215]
------------------------------------------------------------------------------------
G
M
-
K
L
F
K
E
L
----
E
E
T
K
E
Q
V
I
K
M
A
K
L
V
Q
E
A
I
D
K
A
T
E
A
L
N
K
Q
-------
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
I
A
L
Y
Q
P
E
A
G
D
L
R
M
I
M
G
I
Y
K
I
V
S
D
L
E
R
M
G
D
E
A
E
N
I
A
E
R
A
I
L
L
A
E
E
-
P
P
-
L
K
P
Y
V
N
-
I
N
F
M
S
----------
E
I
V
K
E
---
M
V
-----
N
D
S
V
I
S
F
I
Q
--------
Q
D
----
T
L
L
A
K
K
V
I
E
K
D
D
T
V
D
E
L
Y
H
Q
L
E
R
E
L
M
T
Y
V
------
L
E
---
D
P
R
N
I
K
R
A
M
H
L
S
F
V
A
R
H
Y
E
R
I
A
D
---
H
A
E
N
V
A
E
A
A
I
Y
L
S
E
G
E
----------------------------------
13
HHSearch
65.78
34%
-109
- C4 -
-
1T72
-
PHOU_AQUAE
F:
[6-215]
------------------------------------------------------------------------------------
G
M
-
K
L
F
K
E
L
----
E
E
T
K
E
Q
V
I
K
M
A
K
L
V
Q
E
A
I
D
K
A
T
E
A
L
N
K
Q
-------
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
I
A
L
Y
Q
P
E
A
G
D
L
R
M
I
M
G
I
Y
K
I
V
S
D
L
E
R
M
G
D
E
A
E
N
I
A
E
R
A
I
L
L
A
E
E
-
P
P
-
L
K
P
Y
V
N
-
I
N
F
M
S
----------
E
I
V
K
E
---
M
V
-----
N
D
S
V
I
S
F
I
Q
--------
Q
D
----
T
L
L
A
K
K
V
I
E
K
D
D
T
V
D
E
L
Y
H
Q
L
E
R
E
L
M
T
Y
V
------
L
E
---
D
P
R
N
I
K
R
A
M
H
L
S
F
V
A
R
H
Y
E
R
I
A
D
---
H
A
E
N
V
A
E
A
A
I
Y
L
S
E
G
E
----------------------------------
3
PsiBlast_PDB
64.87
32%
-111
- C4 -
-
1T72
-
PHOU_AQUAE
A:
[12-215]
-------------------------------------------------------------------------------------------
E
L
----
E
E
T
K
E
Q
V
I
K
M
A
K
L
V
Q
E
A
I
D
K
A
T
E
A
L
N
K
Q
-------
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
I
A
L
Y
Q
P
E
A
G
D
L
R
M
I
M
G
I
Y
K
I
V
S
D
L
E
R
M
G
D
E
A
E
N
I
A
E
R
A
I
L
L
A
E
E
-
P
-
P
L
K
P
Y
V
N
-
I
N
F
M
S
----------
E
I
V
K
E
---
M
V
-----
N
D
S
V
I
S
F
I
Q
--------
Q
D
----
T
L
L
A
K
K
V
I
E
K
D
D
T
V
D
E
L
Y
H
Q
L
E
R
E
L
M
T
Y
V
------
L
E
---
D
P
R
N
I
K
R
A
M
H
L
S
F
V
A
R
H
Y
E
R
I
A
D
---
H
A
E
N
V
A
E
A
A
I
Y
L
S
E
G
E
----------------------------------
15
HHSearch
64.68
26%
-128
- C4 -
-
1SUM
-
PHOU2_THEMA
B:
[2-221]
------------------------------------------------------------------------------------
N
R
-
L
L
N
E
K
V
----
E
E
F
K
K
G
V
L
K
A
G
W
F
I
E
K
M
F
R
N
S
I
S
S
L
V
E
R
-------
N
----
E
S
L
A
R
E
V
I
A
D
E
E
V
V
D
Q
M
E
V
E
I
Q
E
K
A
M
E
V
L
G
L
F
S
P
I
G
K
P
L
L
T
V
T
A
G
I
R
V
A
E
L
I
E
N
I
A
D
K
C
H
D
I
A
K
N
V
L
E
L
M
E
E
-
P
P
-
L
K
P
L
E
D
-
I
P
A
M
A
----------
N
Q
T
S
E
---
M
L
-----
K
F
A
L
R
M
F
A
D
--------
V
N
----
V
E
K
S
F
E
V
C
R
M
D
S
K
V
D
D
L
Y
E
K
V
R
E
E
L
L
L
Y
M
------
M
E
---
S
P
K
Y
V
K
R
A
L
L
L
L
E
I
A
G
N
I
E
I
I
A
D
---
Y
A
T
N
I
V
E
V
S
V
Y
M
V
Q
G
E
A
Y
K
C
Y
H
D
E
L
L
------------------------
29
Fugue
64.09
25%
-122
* C4 *
-
1SUM
-
PHOU2_THEMA
B:
[2-225]
------------------------------------------------------------------------------------
N
R
-
L
L
N
E
K
V
----
E
E
F
K
K
G
V
L
K
A
G
W
F
I
E
K
M
F
R
N
S
I
S
S
L
V
E
R
-------
N
----
E
S
L
A
R
E
V
I
A
D
E
E
V
V
D
Q
M
E
V
E
I
Q
E
K
A
M
E
V
L
G
L
F
S
P
I
G
K
P
L
L
T
V
T
A
G
I
R
V
A
E
L
I
E
N
I
A
D
K
C
H
D
I
A
K
N
V
L
E
L
-
M
E
-
E
P
P
L
K
P
L
E
D
-
I
P
A
M
A
----------
N
Q
T
S
E
---
M
L
-----
K
F
A
L
R
M
F
A
D
--------
V
N
----
V
E
K
S
F
E
V
C
R
M
D
S
K
V
D
D
L
Y
E
K
V
R
E
E
L
L
L
Y
M
------
M
E
---
S
P
K
Y
V
K
R
A
L
L
L
L
E
I
A
G
N
I
E
I
I
A
D
---
Y
A
T
N
I
V
E
V
S
V
Y
M
V
Q
G
E
A
Y
K
C
Y
H
D
E
L
L
L
---
F
K
K
-----------------
4
PsiBlast_PDB
63.40
28%
-138
- C4 -
-
2I0M
-
PHOU_STRPN
A:
[4-210]
---------------------------------------------------------------------------------------
Q
F
D
L
E
L
----
H
E
L
E
Q
S
F
L
G
L
G
Q
L
V
L
E
T
A
S
K
A
L
L
A
L
A
S
K
-------
D
----
K
E
M
A
E
L
I
I
N
K
D
H
A
I
N
Q
G
Q
S
A
I
E
L
T
C
A
R
L
L
A
L
--
P
Q
V
S
D
L
R
F
V
I
S
I
M
S
S
C
S
D
L
E
R
M
G
D
H
M
A
G
I
A
K
A
V
L
Q
L
K
E
N
-
Q
L
A
--
E
E
-
Q
-
L
H
Q
M
G
----------
K
L
S
L
S
---
M
L
-----
A
D
L
L
V
A
F
P
L
--------
H
Q
----
A
S
K
A
I
S
I
A
Q
K
D
E
Q
I
D
Q
Y
Y
Y
A
L
S
K
E
I
I
G
L
M
------
K
D
---
Q
E
-
S
I
P
N
G
T
Q
Y
L
Y
I
I
G
H
L
E
R
F
A
D
---
Y
I
A
N
I
C
E
R
L
V
Y
L
E
T
G
-----------------------------------
5
PsiBlast_PDB
63.17
30%
-97
- C4 -
-
1XWM
-
?
A:
[5-210]
----------------------------------------------------------------------------------------
F
A
D
D
L
----
A
S
L
H
N
K
L
I
E
M
G
R
L
T
E
V
A
L
Q
Q
A
I
E
A
F
Q
T
Q
-------
N
----
A
N
L
A
M
A
V
I
D
G
D
G
S
I
D
A
L
E
E
E
V
N
D
F
A
L
W
L
I
A
A
Q
Q
P
V
A
T
D
L
R
R
I
V
A
A
I
K
I
A
S
D
I
E
R
I
A
D
F
A
V
N
I
A
K
A
C
I
R
I
----
G
G
Q
P
F
-
V
M
D
-
I
G
P
L
V
----------
L
M
Y
R
L
A
T
D
M
V
-----
S
T
A
I
A
A
Y
D
R
--------
E
D
----
A
S
L
A
A
Q
I
A
D
M
D
H
R
V
D
E
Q
Y
G
E
M
M
A
S
L
L
A
V
A
------
K
T
---
D
A
A
T
L
A
Q
M
N
V
L
A
L
V
A
R
Y
I
E
R
T
A
D
---
H
A
T
N
I
A
E
H
L
V
Y
L
V
K
G
-----------------------------------
6
PsiBlast_PDB
62.74
27%
-73
- C4 -
-
1SUM
-
PHOU2_THEMA
B:
[5-210]
----------------------------------------------------------------------------------------
L
N
E
K
V
----
E
E
F
K
K
G
V
L
K
A
G
W
F
I
E
K
M
F
R
N
S
I
S
S
L
V
E
R
-------
N
----
E
S
L
A
R
E
V
I
A
D
E
E
V
V
D
Q
M
E
V
E
I
Q
E
K
A
M
E
V
L
G
L
F
S
P
I
G
K
P
L
L
T
V
T
A
G
I
R
V
A
E
L
I
E
N
I
A
D
K
C
H
D
I
A
K
N
V
L
E
L
M
E
E
---
P
P
L
K
P
L
E
D
I
P
A
M
A
----------
N
Q
T
S
E
---
M
L
-----
K
F
A
L
R
M
F
A
D
--------
V
N
----
V
E
K
S
F
E
V
C
R
M
D
S
K
V
D
D
L
Y
E
K
V
R
E
E
L
L
L
Y
M
------
M
E
---
S
P
K
Y
V
K
R
A
L
L
L
L
E
I
A
G
N
I
E
I
I
A
D
---
Y
A
T
N
I
V
E
V
S
V
Y
M
V
Q
G
-----------------------------------
11
HHSearch
62.52
28%
-124
- C4 -
-
1XWM
-
?
A:
[4-215]
---------------------------------------------------------------------------------------
T
F
A
D
D
L
----
A
S
L
H
N
K
L
I
E
M
G
R
L
T
E
V
A
L
Q
Q
A
I
E
A
F
Q
T
Q
-------
N
----
A
N
L
A
M
A
V
I
D
G
D
G
S
I
D
A
L
E
E
E
V
N
D
F
A
L
W
L
I
A
A
Q
Q
P
V
A
T
D
L
R
R
I
V
A
A
I
K
I
A
S
D
I
E
R
I
A
D
F
A
V
N
I
A
K
A
C
I
R
I
G
G
Q
-
P
F
V
M
D
-
I
G
P
-
L
V
L
M
Y
----------
R
L
A
T
D
---
M
V
-----
S
T
A
I
A
A
Y
D
R
--------
E
D
----
A
S
L
A
A
Q
I
A
D
M
D
H
R
V
D
E
Q
Y
G
E
M
M
A
S
L
L
A
V
A
------
K
T
---
D
A
A
T
L
A
Q
M
N
V
L
A
L
V
A
R
Y
I
E
R
T
A
D
---
H
A
T
N
I
A
E
H
L
V
Y
L
V
K
G
K
H
Y
D
F
------------------------------
14
HHSearch
62.15
27%
-138
- C4 -
-
2I0M
-
PHOU_STRPN
A:
[4-215]
---------------------------------------------------------------------------------------
Q
F
D
L
E
L
----
H
E
L
E
Q
S
F
L
G
L
G
Q
L
V
L
E
T
A
S
K
A
L
L
A
L
A
S
K
-------
D
----
K
E
M
A
E
L
I
I
N
K
D
H
A
I
N
Q
G
Q
S
A
I
E
L
T
C
A
R
L
L
A
L
--
P
Q
V
S
D
L
R
F
V
I
S
I
M
S
S
C
S
D
L
E
R
M
G
D
H
M
A
G
I
A
K
A
V
L
Q
L
K
E
N
-
Q
L
-
A
--
E
E
Q
-
L
H
Q
M
G
----------
K
L
S
L
S
---
M
L
-----
A
D
L
L
V
A
F
P
L
--------
H
Q
----
A
S
K
A
I
S
I
A
Q
K
D
E
Q
I
D
Q
Y
Y
Y
A
L
S
K
E
I
I
G
L
M
------
K
D
---
Q
E
-
S
I
P
N
G
T
Q
Y
L
Y
I
I
G
H
L
E
R
F
A
D
---
Y
I
A
N
I
C
E
R
L
V
Y
L
E
T
G
E
L
V
D
L
------------------------------
2
PsiBlast_PDB
60.82
34%
-107
- C4 -
-
1T8B
-
PHOU_AQUAE
A:
[12-214]
-------------------------------------------------------------------------------------------
E
L
----
E
E
T
K
E
Q
V
I
K
M
A
K
L
V
Q
E
A
I
D
K
A
T
E
A
L
N
K
Q
-------
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
I
A
L
Y
Q
P
E
A
G
D
L
R
M
I
M
G
I
Y
K
I
V
S
D
L
E
R
M
G
D
E
A
E
N
I
A
E
R
A
I
L
L
A
E
E
-
P
-
P
L
K
P
Y
V
N
-
I
N
F
M
S
----------
E
I
V
K
E
---
M
V
-----
N
D
S
V
I
S
F
I
Q
--------
Q
D
----
T
L
L
A
K
K
V
I
E
K
D
D
T
V
D
E
L
Y
H
Q
L
E
R
E
L
M
T
Y
V
------
L
E
---
D
P
R
N
I
K
R
A
M
H
L
S
F
V
A
R
H
Y
E
R
I
A
D
---
H
A
E
N
V
A
E
A
A
I
Y
L
S
E
G
-----------------------------------
7
PsiBlast_PDB
44.50
38%
-332
* C5 *
-
5X3F
-
?
B:
[11-40]
------------------------------------------------------------------------------------------
K
E
T
----
Q
E
A
S
W
E
I
F
T
L
P
N
L
N
G
R
Q
V
A
A
F
I
S
S
L
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
38.23
18%
-
- C4 -
-
3ZPJ
-
?
A:
[1-356]
M
T
T
L
E
E
I
N
L
L
V
E
R
GY
Y
E
E
A
L
A
K
V
YEIED
P
I
E
Q
V
Q
V
L
T
K
I
V
V
T
I
Y
Q
H
DGPMEW
I
P
S
I
M
E
D
A
M
Y
I
A
K
K
LRD
P
A
N
K
A
V
A
Y
S
I
I
A
S
T
L
A
I
M
E
Y
E
E
D
A
----
M
D
F
F
N
R
A
I
D
E
A
N
E
I
E
S
P
I
E
K
G
M
V
-
L
S
T
L
-------
A
----
Y
H
L
A
I
-
A
G
Y
P
D
N
A
L
E
I
F
N
I
A
F
D
T
I
I
G
A
E
T
S
Y
T
H
K
V
D
G
I
L
R
I
G
D
L
L
E
K
A
G
D
T
L
P
--
S
N
E
A
M
D
F
Y
K
M
A
F
D
I
F
D
K
L
H
V
N
Q
R
A
A
I
V
-
E
K
K
I
E
L
A
K
T
V
YDVGL
P
Q
I
R
A
---
A
L
L
K
GK
N
H
Y
A
L
A
I
I
K
K
K
YSG
V
M
R
-
L
I
----
G
E
L
E
V
A
L
W
M
K
R
V
N
-
N
M
E
Y
L
D
V
V
D
K
A
F
E
C
C
ESPRFT
D
V
---
N
V
Q
H
I
A
R
L
L
T
E
L
G
N
L
R
R
A
L
K
F
A
K
E
IQ
N
I
H
K
R
S
E
A
L
K
A
I
A
L
E
L
V
R
R
K
-
K
F
E
E
V
K
K
I
I
E
S
I
PD
P
K
I
R
E
E
A
L
N
E
I
GTIE
18
HHSearch
34.00
11%
-52
- C4 -
-
2OLT
2
?
C:
[14-224]
--------------------------------------------------------------------------------------------------
S
P
I
K
P
L
Q
E
H
M
D
K
V
Y
D
C
A
S
L
L
V
P
F
F
E
A
T
I
T
GN
W
D
D
A
----
V
Q
I
R
K
Q
I
S
L
A
E
K
Q
G
D
S
L
K
R
E
I
R
L
T
L
--
G
L
--
F
M
P
V
--
E
R
T
---
D
L
L
E
L
L
T
Q
Q
D
K
I
A
N
K
A
K
D
I
S
G
R
V
I
G
R
Q
L
L
--
I
P
Q
A
L
Q
V
P
-
F
I
A
Y
L
----------
Q
R
C
I
D
---
A
V
G
L
A
--
Q
Q
V
I
N
E
L
D
D
L
L
E
AGFRG
R
E
V
D
F
V
A
K
M
I
N
E
L
D
I
I
E
E
D
T
D
D
L
Q
I
Q
L
R
R
Q
L
F
A
L
E
------
S
-----
E
L
N
P
V
D
V
M
F
L
Y
K
T
I
E
W
V
G
G
L
A
D
---
L
A
E
R
V
G
S
R
L
E
L
M
L
-------------------------------------
19
HHSearch
33.77
22%
-109
- C4 -
-
2BKP
-
?
A:
[9-106]
------------------------------------------------------------------------------------------
Y
E
P
----
K
S
V
K
E
I
F
I
E
M
K
D
T
V
E
L
M
V
D
L
A
Y
A
S
L
L
F
G
-------
D
----
K
E
I
A
E
E
V
L
E
L
E
E
R
I
D
L
L
N
Y
Q
L
M
M
H
S
V
L
A
-
A
R
N
V
---
K
E
A
E
Q
V
I
T
I
L
Q
I
A
N
A
I
E
D
I
S
N
A
A
G
D
L
A
K
M
V
L
E
G
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
33.65
22%
-116
- C4 -
-
1T72
-
PHOU_AQUAE
D:
[14-114]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
T
K
E
Q
-
V
I
K
M
A
----------
K
L
V
Q
E
---
A
I
-----
D
K
A
T
E
A
L
N
K
--------
Q
N
----
V
E
L
A
E
E
V
I
K
G
D
D
T
I
D
L
L
E
V
D
I
E
R
R
C
I
R
M
I
------
A
L
YQP
E
A
G
D
L
R
M
I
M
G
I
Y
K
I
V
S
D
L
E
R
M
G
D
---
E
A
E
N
I
A
E
R
A
I
L
L
A
E
E
-----------------------------------
16
HHSearch
33.60
11%
33
- C4 -
-
3L39
-
?
A:
[19-223]
------------------------------------------------------------------------------------------
S
K
F
T
P
K
E
P
K
F
F
P
L
L
K
Q
L
S
D
V
L
S
A
S
S
V
L
L
V
E
S
M
E
H
D
-------
L
P
T
E
R
A
D
Y
Y
K
Q
I
K
D
M
E
R
E
G
D
R
L
T
H
L
I
F
D
E
L
S
T
T
F
I
-
T
-
P
F
D
R
E
-----
D
I
H
D
L
A
S
C
M
D
D
V
I
D
G
I
N
S
S
A
K
R
I
V
I
Y
N
P
R
-----
P
I
S
E
S
-
G
K
E
L
S
----------
R
L
I
H
E
---
E
A
I
N
I
--
G
K
A
M
D
E
L
E
T
FR------
K
N
P
K
P
L
R
D
Y
C
T
Q
L
H
D
I
E
N
Q
A
D
D
V
Y
E
L
F
I
T
K
L
F
E
E
-------------
E
K
D
C
I
E
L
I
K
I
K
E
I
M
H
E
L
E
K
T
T
D
---
A
A
E
H
V
G
K
I
L
K
N
L
I
-------------------------------------