@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMH1: (2017-11-08 )
MKKMLMALSLTGALLGGTAAWAEETVTTPTSEVTATSTSEAPATIAAAPAAEETPAAPTPTAKLDTGDTSWILISTALVLLMTIPGLALFYGGMVRKKNVLSTMMFSLSAAILVSLLWVIAGYSIAFSGTGAYFGDLSKAMLNGVAFDALSGTIPESLFVIFQMTFAIITVAILSGSIADRMKYSAFMAFIAIWVLVVYAPITHWVWAADGWLFKAGALDFAGGTVVHINSGVAGLVAAYMLGKRIGLGRESMAPHNLTLTVIGASLLWVGWFGFNGGSALGAGARASMAILVTQVAAAAAAFSWLVVERMIRGKASVLGGASGAVAGLVVITPAAGFVGVGGALVMGLIGGVVCFWGITALKRLLKADDALDAFGLHAVGGIVGAILTGVFYSDEIIKAANVALAPTFAGQLWVQVEGVLATMVYSGIATFIILKVIDLIIGLRVNSDDERMGLDLSQHGERIE
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80...-.....90........100.......110.......120.....-.---------.130-.........140..----...-..150.......160.......170.......180.......190.......200.......210.......220.......230.......240...----....250-.........260.......270.......280.......290.......300.......310.-....-...320.......330.......340.......350.......360........370.......380.......390.......400------.......-------.410------....-....420.......430.......440.--........450.......460...-------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MK
K
M
L
M
A
L
S
L
T
G
A
L
LGGT
A
A
WAEETVTTPTS
E
V
T
ATSTSEAP
A
T
I
AAAPAAEETPAAPTPTAKLDTGDT
S
W
I
L
I
S
T
A
L
V
L
L
M
TI-
P
G
L
A
L
F
YGGM
V
R
K
K
N
V
L
S
T
M
M
F
S
L
S
A
A
I
L
V
S
L
L
W
V
IAG
Y
S
I
A
F
-S---------GT---G
A
Y
F
G
D
L
S
K
A
M
L
N
G
----
V
A
F
-
D
A
LSGTI
P
E
S
L
F
V
I
F
Q
M
T
F
A
I
I
T
V
A
I
LSG
S
I
A
D
R
M
K
Y
S
A
F
M
A
F
I
A
I
W
V
L
V
V
Y
API
T
H
W
V
WAADG
W
L
F
KAGALDFAG
G
T
V
V
H
INSG
V
A
G
L
V
A
A
Y
M
L
G
K
R----IGLGR---ESMAPH
N
L
T
L
T
V
IGA
S
L
L
W
V
G
W
FGFNGGSALGAGAR
A
S
M
A
I
L
V
T
Q
V
A
A
A
A
A
A
F
S
W
L
V
V
E
R
M
-I-RG
K
A
-
S
VLGGASG
A
V
A
G
L
V
V
I
TPAA
G
F
VG
V
G
G
A
L
V
M
G
L
I
G
G
V
V
C
F
W
G
I
T
-
A
L
K
R
L
L
KADD
A
L
D
A
F
G
L
H
A
V
G
G
I
V
G
A
I
L
T
G
V
FY
S
D
E
I
I
K
AA-------N
V
A
LAPT-------FA
G
-------
Q
L
W
V
-
Q
V
E
G
V
L
A
T
M
V
Y
S
G
I
A
T
F
I
I
L
K
V
I
D
L
--
I
--
I
G
L
R
VNSDDERMGL
D
L
S
QHGERIE-------------
4
PsiBlast_PDB
84.01
48%
-164
- C2 -
-
2NS1
10
AMTB_ECOLI
A:
[6-402]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
G
F
G
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
E
E
Q
E
R
E
G
L
D
V
N
S
H
G
E
N
---------------
27
Fugue
83.64
37%
-112
- C2 -
-
5AEX
-
MEP2_YEAST
A:
[2-457]
------
S
Y
N
F
T
G
---------------
T
P
T
G
E
G
T
G
G
N
S
L
T
T
-----------------
D
L
N
T
Q
F
D
L
A
N
M
G
W
I
G
V
A
S
A
G
V
W
I
M
-
V
-
P
G
I
G
L
L
Y
S
G
L
S
R
K
K
H
A
L
S
L
L
W
A
S
M
M
A
S
A
V
C
I
F
Q
W
F
F
W
G
Y
S
L
A
F
-
S
---------
H
N
---
T
R
G
N
G
F
I
G
T
L
E
F
F
G
FRNV
L
G
A
-
P
S
S
V
S
S
L
P
D
I
L
F
A
V
Y
Q
G
M
F
A
A
V
T
G
A
L
M
L
G
G
A
C
E
R
A
R
L
F
P
M
M
V
F
L
F
L
W
M
T
I
V
Y
C
P
I
A
C
W
V
W
N
A
E
G
W
L
V
K
L
G
S
L
D
Y
A
G
G
L
C
V
H
L
T
S
G
H
G
G
L
V
Y
A
L
I
L
G
K
R
NDPV
T
R
K
G
M
---
P
K
Y
K
P
H
S
V
T
S
V
V
L
G
T
V
F
L
W
F
G
W
M
F
F
N
G
G
S
A
G
N
A
T
I
R
A
W
Y
S
I
M
S
T
N
L
A
A
A
C
G
G
L
T
W
M
V
I
D
Y
F
R
C
-
G
R
K
W
-
T
T
V
G
L
C
S
G
I
I
A
G
L
V
G
I
T
P
A
A
G
F
V
P
I
W
S
A
V
V
I
G
V
V
T
G
A
G
C
N
L
A
V
D
--
L
K
S
L
L
R
I
D
D
G
L
D
C
Y
S
I
H
G
V
G
G
C
I
G
S
V
L
T
G
I
F
A
A
D
Y
V
N
A
T
A
-------
G
S
Y
I
S
P
I
DGGWINH
H
Y
K
-------
Q
V
G
Y
-
Q
L
A
G
I
C
A
A
L
A
W
T
V
T
V
T
S
I
L
L
L
T
M
N
A
--
I
PF
L
K
L
R
L
S
A
D
E
E
E
L
G
T
D
A
A
Q
I
G
E
F
T
Y
EESTAYIPEPIRS
2
PsiBlast_PDB
83.48
48%
-162
- C2 -
-
2NUU
-
AMTB_ECOLI
A:
[15-411]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
G
F
G
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
E
E
Q
E
R
E
G
L
D
V
N
S
H
G
E
N
---------------
10
PsiBlast_PDB
82.44
47%
-177
- C2 -
-
1U7C
1
AMTB_ECOLI
A:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
S
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
P
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
G
F
G
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
L
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
41
HHSearch
81.56
47%
-175
- C2 -
-
1U7C
1
AMTB_ECOLI
A:
[3-385]
-------------------------------------------------------------
A
V
A
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
-
T
I
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
S
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
P
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
-
G
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
V
---
G
F
G
-
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
L
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
L
G
G
V
G
-------
F
A
-
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
11
PsiBlast_PDB
81.25
47%
-174
- C2 -
-
1U7G
4
AMTB_ECOLI
A:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
S
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
P
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
G
F
G
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
L
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
38
HHSearch
81.10
47%
-151
- C2 -
-
2B2J
13
?
A:
[2-390]
----------------------------------------------------------------
S
D
G
N
V
A
W
I
L
A
S
T
A
L
V
M
L
M
-
V
-
P
G
V
G
F
F
Y
A
G
M
V
R
R
K
N
A
V
N
M
I
A
L
S
F
I
S
L
I
I
T
V
L
L
W
I
F
Y
G
Y
S
V
S
F
-
G
---------
N
D
I--
S
G
I
I
G
G
L
N
Y
A
L
L
S
G
----
V
--------
K
G
E
D
L
L
F
M
M
Y
Q
M
M
F
A
A
V
T
I
A
I
L
T
S
A
I
A
E
R
A
K
V
S
S
F
I
L
L
S
A
L
W
L
T
F
V
Y
A
P
F
A
H
W
L
W
G
-
G
G
W
L
A
K
L
G
A
L
D
F
A
G
G
M
V
V
H
I
S
S
G
F
A
A
L
A
V
A
M
T
I
G
K
R
A---
G
F
E
-
E
---
Y
S
I
E
P
H
S
I
P
L
T
L
I
G
A
A
L
L
W
F
G
W
F
G
F
N
G
G
S
A
L
A
A
N
D
V
A
I
N
A
V
V
V
T
N
T
S
A
A
V
A
G
F
V
W
M
V
I
G
W
I
-
K
--
G
K
P
-
G
S
L
G
I
V
S
G
A
I
A
G
L
A
A
I
T
P
A
A
G
F
V
D
V
K
G
A
I
V
I
G
L
V
A
G
I
V
C
Y
L
A
M
D
-
F
R
I
-
K
K
K
I
D
E
S
L
D
A
W
A
I
H
G
I
G
G
L
W
G
S
V
A
V
G
I
L
A
N
P
E
V
N
G
Y
---------
A
G
L
L
F
G
-------
N
P
Q
-------
L
L
V
S
-
Q
L
I
A
V
A
S
T
T
A
Y
A
F
L
V
T
L
I
L
A
K
A
V
D
A
--
A
--
V
G
L
R
V
S
S
Q
E
E
Y
V
G
L
D
L
S
Q
H
E
E
V
A
Y
-------------
21
PsiBlast_CBE
80.89
48%
-186
- C2 -
-
4NH2
2
AMTB_ECO57
F:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
---------
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
42
HHSearch
80.88
47%
-174
- C2 -
-
1U7G
4
AMTB_ECOLI
A:
[3-385]
-------------------------------------------------------------
A
V
A
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
-
T
I
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
S
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
P
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
-
G
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
V
---
G
F
G
-
K
---
E
A
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
L
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
R
V
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
L
G
G
V
G
-------
F
A
-
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
23
PsiBlast_CBE
80.40
48%
-184
- C2 -
-
4NH2
1
AMTB_ECO57
D:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
-------
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
16
PsiBlast_PDB
80.39
37%
-116
- C2 -
-
5AEX
-
MEP2_YEAST
A:
[24-441]
------------------------------------------------------------
N
T
Q
F
D
L
A
N
M
G
W
I
G
V
A
S
A
G
V
W
I
M
-
V
-
P
G
I
G
L
L
Y
S
G
L
S
R
K
K
H
A
L
S
L
L
W
A
S
M
M
A
S
A
V
C
I
F
Q
W
F
F
W
G
Y
S
L
A
F
-
S
HNTRGNGFI
G
T
---
L
E
F
F
G
-----
F
R
N
V
----
L
G
A
-
P
S
S
V
S
S
L
P
D
I
L
F
A
V
Y
Q
G
M
F
A
A
V
T
G
A
L
M
L
G
G
A
C
E
R
A
R
L
F
P
M
M
V
F
L
F
L
W
M
T
I
V
Y
C
P
I
A
C
W
V
W
N
A
E
G
W
L
V
K
L
G
S
L
D
Y
A
G
G
L
C
V
H
L
T
S
G
H
G
G
L
V
Y
A
L
I
L
G
K
R
NDPV
T
R
K
G
M
---
P
K
Y
K
P
H
S
V
T
S
V
V
L
G
T
V
F
L
W
F
G
W
M
F
F
N
G
G
S
A
G
N
A
T
I
R
A
W
Y
S
I
M
S
T
N
L
A
A
A
C
G
G
L
T
W
M
V
I
D
Y
F
-
R
-
C
G
R
K
W
T
T
V
G
L
C
S
G
I
I
A
G
L
V
G
I
T
P
A
A
G
F
V
P
I
W
S
A
V
V
I
G
V
V
T
G
A
G
C
N
L
A
V
D
--
L
K
S
L
L
R
I
D
D
G
L
D
C
Y
S
I
H
G
V
G
G
C
I
G
S
V
L
T
G
I
F
A
A
D
Y
V
N
A
T
A
-------
G
S
Y
I
S
P
I
-------
D
G
G
WINHHYK
Q
V
G
Y
-
Q
L
A
G
I
C
A
A
L
A
W
T
V
T
V
T
S
I
L
L
L
T
M
N
A
--
I
PF
L
K
L
R
L
S
A
D
E
E
E
L
G
T
D
A
A
Q
I
G
E
----------------
3
PsiBlast_PDB
80.38
48%
-182
- C2 -
-
1XQE
-
AMTB_ECOLI
A:
[6-386]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
-------
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
-------------------------------
37
HHSearch
80.31
37%
-122
- C2 -
-
5AEX
-
MEP2_YEAST
F:
[21-444]
---------------------------------------------------------
T
D
L
N
T
Q
F
D
L
A
N
M
G
W
I
G
V
A
S
A
G
V
W
I
M
-
V
-
P
G
I
G
L
L
Y
S
G
L
S
R
K
K
H
A
L
S
L
L
W
A
S
M
M
A
S
A
V
C
I
F
Q
W
F
F
W
G
Y
S
L
A
F
-
S
---------
H
N
TRG
N
G
F
I
G
T
L
E
F
F
G
F
R
N
----
V
L
G
A
P
S
S
V
S
S
L
P
D
I
L
F
A
V
Y
Q
G
M
F
A
A
V
T
G
A
L
M
L
G
G
A
C
E
R
A
R
L
F
P
M
M
V
F
L
F
L
W
M
T
I
V
Y
C
P
I
A
C
W
V
W
N
A
E
G
W
L
V
K
L
G
S
L
D
Y
A
G
G
L
C
V
H
L
T
S
G
H
G
G
L
V
Y
A
L
I
L
G
K
R
N---
D
P
V
T
R
KGM
P
K
Y
K
P
H
S
V
T
S
V
V
L
G
T
V
F
L
W
F
G
W
M
F
F
N
G
G
S
A
G
N
A
T
I
R
A
W
Y
S
I
M
S
T
N
L
A
A
A
C
G
G
L
T
W
M
V
I
D
Y
F
-
R
C
G
R
K
W
-
T
T
V
G
L
C
S
G
I
I
A
G
L
V
G
I
T
P
A
A
G
F
V
P
I
W
S
A
V
V
I
G
V
V
T
G
A
G
C
N
L
A
V
D
-
L
K
S
-
L
L
R
I
D
D
G
L
D
C
Y
S
I
H
G
V
G
G
C
I
G
S
V
L
T
G
I
F
A
A
D
Y
V
N
A
T
A
GSYISPI
D
G
G
W
I
N
H
-------
H
Y
K
-------
Q
V
G
Y
-
Q
L
A
G
I
C
A
A
L
A
W
T
V
T
V
T
S
I
L
L
L
T
M
N
A
IP
F
--
L
K
L
R
L
S
A
D
E
E
E
L
G
T
D
A
A
Q
I
G
E
F
T
Y
-------------
22
PsiBlast_CBE
80.26
48%
-181
- C2 -
-
4NH2
2
AMTB_ECO57
E:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
-----------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
------
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
5
PsiBlast_PDB
80.06
48%
-176
- C2 -
-
2NOW
1
AMTB_ECOLI
A:
[6-386]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
E
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
-----
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
-------------------------------
25
PsiBlast_CBE
80.05
48%
-185
- C2 -
-
4NH2
4
AMTB_ECO57
B:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
------------------
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
-------
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
39
HHSearch
80.02
47%
-151
- C2 -
-
2B2H
-
?
A:
[2-390]
----------------------------------------------------------------
S
D
G
N
V
A
W
I
L
A
S
T
A
L
V
M
L
M
-
V
-
P
G
V
G
F
F
Y
A
G
M
V
R
R
K
N
A
V
N
M
I
A
L
S
F
I
S
L
I
I
T
V
L
L
W
I
F
Y
G
Y
S
V
S
F
-
G
---------
N
D
I--
S
G
I
I
G
G
L
N
Y
A
L
L
S
G
----
V
--------
K
G
E
D
L
L
F
M
M
Y
Q
M
M
F
A
A
V
T
I
A
I
L
T
S
A
I
A
E
R
A
K
V
S
S
F
I
L
L
S
A
L
W
L
T
F
V
Y
A
P
F
A
H
W
L
W
G
-
G
G
W
L
A
K
L
G
A
L
D
F
A
G
G
M
V
V
H
I
S
S
G
F
A
A
L
A
V
A
M
T
I
G
K
R
A---
G
F
E
-
E
---
Y
S
I
E
P
H
S
I
P
L
T
L
I
G
A
A
L
L
W
F
G
W
F
G
F
N
G
G
S
A
L
A
A
N
D
V
A
I
N
A
V
V
V
T
N
T
S
A
A
V
A
G
F
V
W
M
V
I
G
W
I
-
K
--
G
K
P
-
G
S
L
G
I
V
S
G
A
I
A
G
L
A
A
I
T
P
A
A
G
F
V
D
V
K
G
A
I
V
I
G
L
V
A
G
I
V
C
Y
L
A
M
D
-
F
R
I
-
K
K
K
I
D
E
S
L
D
A
W
A
I
H
G
I
G
G
L
W
G
S
V
A
V
G
I
L
A
N
P
E
V
N
G
Y
---------
A
G
L
L
F
G
-------
N
P
Q
-------
L
L
V
S
-
Q
L
I
A
V
A
S
T
T
A
Y
A
F
L
V
T
L
I
L
A
K
A
V
D
A
--
A
--
V
G
L
R
V
S
S
Q
E
E
Y
V
G
L
D
L
S
Q
H
E
E
V
A
Y
-------------
1
PsiBlast_PDB
80.01
48%
-188
- C2 -
-
4NH2
2
AMTB_ECO57
A:
[6-385]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
----------
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
--------------------------------
8
PsiBlast_PDB
79.96
47%
-174
- C2 -
-
2NPK
2
AMTB_ECOLI
A:
[6-386]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
A
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
G
K
R
----
V
---------
F
K
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
F
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
L
K
R
L
L
--
D
D
P
C
D
V
F
G
V
A
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
-------------------------------
6
PsiBlast_PDB
79.94
48%
-179
- C2 -
-
3C1I
1
AMTB_ECOLI
A:
[6-386]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
F
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
A
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
-------
D
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
-------------------------------
15
PsiBlast_PDB
79.73
46%
-136
- C2 -
-
2B2J
13
?
A:
[1-387]
---------------------------------------------------------------
M
S
D
G
N
V
A
W
I
L
A
S
T
A
L
V
M
L
M
-
V
-
P
G
V
G
F
F
Y
A
G
M
V
R
R
K
N
A
V
N
M
I
A
L
S
F
I
S
L
I
I
T
V
L
L
W
I
F
Y
G
Y
S
V
S
F
G
N
---------
D
I
---
S
G
I
I
G
G
L
N
Y
A
L
L
S
G
----
V
K
G
-
E
D
L
-------
L
F
M
M
Y
Q
M
M
F
A
A
V
T
I
A
I
L
T
S
A
I
A
E
R
A
K
V
S
S
F
I
L
L
S
A
L
W
L
T
F
V
Y
A
P
F
A
H
W
L
W
G
G
-
G
W
L
A
K
L
G
A
L
D
F
A
G
G
M
V
V
H
I
S
S
G
F
A
A
L
A
V
A
M
T
I
G
K
R
----
A
G
F
E
E
---
Y
S
I
E
P
H
S
I
P
L
T
L
I
G
A
A
L
L
W
F
G
W
F
G
F
N
G
G
S
A
L
A
A
N
D
V
A
I
N
A
V
V
V
T
N
T
S
A
A
V
A
G
F
V
W
M
V
I
-
G
W
-
I
-
K
G
K
P
-
G
S
L
G
I
V
S
G
A
I
A
G
L
A
A
I
T
P
A
A
G
F
V
D
V
K
G
A
I
V
I
G
L
V
A
G
I
V
C
Y
L
A
M
D
F
R
I
K
K
--
K
I
D
E
S
L
D
A
W
A
I
H
G
I
G
G
L
W
G
S
V
A
V
G
I
L
A
N
P
E
V
N
G
Y
A
-------
G
L
L
F
G
N
P
-----------------
Q
L
L
V
S
Q
L
I
A
V
A
S
T
T
A
Y
A
F
L
V
T
L
I
L
A
K
A
V
D
A
--
A
--
V
G
L
R
V
S
S
Q
E
E
Y
V
G
L
D
L
S
Q
H
E
E
----------------
7
PsiBlast_PDB
79.46
47%
-179
- C2 -
-
3C1J
2
AMTB_ECOLI
A:
[6-386]
----------------------------------------------------------------
D
K
A
D
N
A
F
M
M
I
C
T
A
L
V
L
F
M
T
I
-
P
G
I
A
L
F
Y
G
G
L
I
R
G
K
N
V
L
S
M
L
T
Q
V
T
V
T
F
A
L
V
C
I
L
W
V
V
Y
G
Y
S
L
A
F
-
G
---------
E
G
---
N
N
F
F
G
N
I
N
W
L
M
L
K
N
----
I
E
L
-
T
A
V
M
G
S
I
Y
Q
Y
I
H
V
A
F
Q
G
S
A
A
C
I
T
V
G
L
I
V
G
A
L
A
E
R
I
R
F
S
A
V
L
I
F
V
V
V
W
L
T
L
S
Y
I
P
I
A
H
M
V
W
G
G
-
G
L
L
A
S
H
G
A
L
D
F
A
G
G
T
V
V
H
I
N
A
A
I
A
G
L
V
G
A
Y
L
I
-------------------
P
H
N
L
P
M
V
F
T
G
T
A
I
L
Y
I
G
W
F
G
A
N
A
G
S
A
G
T
A
N
E
I
A
A
L
A
F
V
N
T
V
V
A
T
A
A
A
I
L
G
W
I
F
G
E
W
A
-
L
-
R
G
K
P
-
S
L
L
G
A
C
S
G
A
I
A
G
L
V
G
V
T
P
A
C
G
Y
I
G
V
G
G
A
L
I
I
G
V
V
A
G
L
A
G
L
W
G
V
T
-
M
--------
D
P
C
D
V
F
G
V
H
G
V
C
G
I
V
G
C
I
M
T
G
I
F
A
A
S
S
-
L
G
G
V
-------
G
F
A
E
G
V
T
-------
M
G
H
-------
Q
L
L
V
-
Q
L
E
S
I
A
I
T
I
V
W
S
G
V
V
A
F
I
G
Y
K
L
A
D
L
--
T
--
V
G
L
R
V
P
-------------------------------