@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMJ1: (2017-11-08 )
MTYFELVRSMDVLEKITLPGKPKYLKLAEDFDFYELFKKIENQFSTCFIFESLGEEDYLSRHHIIGFDPEKFFYSTAVNELCVKDCTTNTILKYSCDHAYYKLREIVPQNIISKHYSGGLVGFIGYNAISFFEPTLDVKNNEDFETFKFGLYLDGLVYDKLTGEIFYFYYKESRFNEILDILNSDINYNNNIKVQYLGNSVTKEEYENSVYKVKEYIKSGLIFQCEVGFKTDYIITGNHLEIYSKLREVNPSPHMYFMKFDDQKIIGASPELLFRLHNKEMETFPLAGTAKRGKDEIEDRKYARKLLNDPKEIAEHNMLVDLHRNDIGRVAQFGTVKVRKLMDIKRFSHIQHISSEIVGIIKEDEDMFSALASNFPAGTLSGAPKIEAMKIIDEIESSGRGVYGGAIGEFCFNGDCTFAIPIRSIFIKADRAYIQTCGGNVFDSNPEDEYIEIERKLAAMKTVLKNFEV
Atome Classification :
(20 SA)
.........10........20........-30-........40..-......50........60........----70.....-...80........---90-----------------------------------.------------------------------------........100...--....-110--.-..-....-------------------------------------..120.......130..----.....-140.-.......150------------.......------160......----------.170-----..------.-----------.-.....180-------.-------.-...------..---.-190----.------.......--.200.......210.......220.......230....--...240.......250.......260-----........270-.....--.--..280.......290..------..------...300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
T
Y
F
E
L
V
R
S
M
D
V
L
E
K
ITLPGKP
K
Y
L
K
LAE-DF-
D
F
Y
E
L
F
K
K
I
E
N
Q
-
F
S
T
C
F
I
F
E
SLGE
E
D
Y
L
SRHHIIGF
D
P
----
E
K
F
F
Y
S
T
-
A
V
N
E
L
C
V
K
DCTTN---
T
------------------------------------
I
------------------------------------
L
K
YSC
D
H
A
Y
Y
K
L
R
E
--
I
V
P
Q
-
N
----
I
-
I
S
-
K
HYS-------------------------------------G
G
L
V
G
FIGY
N
A
I
S
FFEP----TLDVK-NN-E-DF
E
T
F
K
F
G
L
Y
------------LD
G
L
V
Y
D------KLTG
E
I
F
Y
F
----------
Y
Y-------
K
E
------
S
-----------
R
-
F
N
E
I
L
D
-
I
-------
L
-------N-SDI------NY---N-N------
N
------
I
K
V
Q
YLG--NSV
T
K
E
E
YE
N
S
V
Y
K
V
K
E
Y
I
KSG
L
I
F
Q
C
EVGFK
T
D
Y
I
I
T--G
N
H
L
E
I
Y
S
K
L
R
EVNPSP
H
M
Y
F
M
KFD------DQKIIGA
S
P
E
--
L
L
F
R
L
--H--NKEMETFPLAGTAKRG
K
------
D
E
------
I
E
D
R
K
Y
A
R
K
L
LN
D
P
K
E
I
A
EH
N
M
L
V
D
LHRN
D
I
G
R
V
A
Q
F
G
T
V
K
V
R
K
L
M
D
I
K
R
F
S
H
I
Q
H
I
S
S
E
I
V
G
I
IKE
D
E
D
M
F
S
A
L
A
SNFPAGTLSGAP
K
I
E
A
M
K
I
I
D
E
I
E
SSGRGVYGGA
I
G
E
F
C
FNGD
C
T
F
A
I
P
I
R
S
I
F
I
KA
D
R
A
Y
I
Q
TCGGNVFDSNPE
D
E
Y
I
E
I
E
R
K
L
A
A
M
K
T
V
L
K
NFEV-
31
HHSearch
80.53
39%
-3
- C1 -
-
1QDL
-
TRPE_SULSO
A:
[5-420]
-------------------------
P
I
S
E
-
F
A
-
S
P
F
E
V
F
K
C
I
E
R
D
-
F
K
V
A
G
L
L
E
S
I
-------
R
Y
S
V
I
A
W
S
T
----
N
G
Y
L
K
I
H
------------------------------------------------------------------------------------------------
D
D
P
V
N
I
L
N
G
--
Y
L
K
D
L
K
----
L
A
D
I
P
G
L
F
K
-------------------------------------
G
G
M
I
G
Y
I
S
Y
D
A
V
R
F
W
E
K
----
I
R
D
L
K
-
P
A
A
E
-
D
W
P
Y
A
E
F
F
T
P
------------
D
N
I
I
I
Y
D
------
H
N
E
G
K
V
Y
V
N
----------
A
D
-------
L
S
------
S
-------------
V
G
-----
G
-------
C
-------
G
-
D
-------------
I
-
G
------
E
------
F
K
V
S
F
Y
D
--
E
S
L
N
K
N
S
Y
E
R
I
V
S
E
S
L
E
Y
I
R
S
G
Y
I
F
Q
V
V
L
S
R
F
Y
R
Y
I
F
S
--
G
D
P
L
R
I
Y
Y
N
L
R
R
I
N
P
S
P
Y
M
F
Y
L
K
F
D
------
E
K
Y
L
I
G
S
S
P
E
--
L
L
F
R
V
--
Q
--
D
N
I
V
E
T
Y
P
I
A
G
T
R
P
R
G
A
------
D
Q
------
E
E
D
L
K
L
E
L
E
L
M
N
S
E
K
D
K
A
E
H
L
M
L
V
D
L
A
R
N
D
L
G
K
V
C
V
P
G
T
V
K
V
P
E
L
M
Y
V
E
K
Y
S
H
V
Q
H
I
V
S
K
V
I
G
T
L
K
K
K
Y
N
A
L
N
V
L
S
A
T
F
P
A
G
T
V
S
G
A
P
K
P
M
A
M
N
I
I
E
T
L
E
E
Y
K
R
G
P
Y
A
G
A
V
G
F
I
S
A
D
G
N
A
E
F
A
I
A
I
R
T
A
F
L
N
K
E
L
L
R
I
H
A
G
A
G
I
V
Y
D
S
N
P
E
S
E
Y
F
E
T
E
H
K
L
K
A
L
K
T
A
I
G
V
----
29
HHSearch
80.51
30%
12
- C1 -
-
5CWA
4
TRPE_MYCTO
A:
[21-506]
---------------
A
E
H
R
V
V
P
V
T
R
K
V
L
A
D
S
E
-
T
P
L
S
A
Y
R
K
L
A
A
N
-
R
P
G
T
F
L
L
E
S
A
E
N
G
R
S
W
S
R
W
S
F
I
G
A
G
A
----
P
T
A
L
T
V
R
-
E
G
Q
A
V
W
L
G
A
V
P
------------------------------------------
K
------------------------------------
D
A
P
T
G
G
D
P
L
R
A
L
Q
V
--
T
L
E
L
L
A
TAD---
P
G
L
P
P
L
S
-------------------------------------
G
G
M
V
G
F
F
A
Y
D
M
V
R
R
L
E
R
----
L
P
E
R
A
-
V
D
D
L
-
C
L
P
D
M
L
L
L
L
A
------------
T
D
V
A
A
V
D
------
H
H
E
G
T
I
T
L
I
----------
A
N
-------
A
V
------
N
WNGTDER
V
D
--
W
A
Y
D
D
A
V
A
-
R
L
D
V
M
T
A
A
L
-------
G
-
Q
P
L
------
P
S
---
T
V
A
T
F
----
S
------
R
P
E
P
R
H
R
--
A
Q
R
T
V
E
E
Y
G
A
I
V
E
Y
L
V
D
Q
I
A
A
G
E
A
F
Q
V
V
P
S
Q
R
F
E
M
D
T
D
--
V
D
P
I
D
V
Y
R
I
L
R
V
T
N
P
S
P
Y
M
Y
L
L
Q
V
P
N
SDGAV
D
F
S
I
V
G
S
S
P
E
--
A
L
V
T
V
--
H
--
E
G
W
A
T
T
H
P
I
A
G
T
R
W
R
G
R
------
T
D
------
D
E
D
V
L
L
E
K
E
L
L
A
D
D
K
E
R
A
E
H
L
M
L
V
D
L
G
R
N
D
L
G
R
V
C
T
P
G
T
V
R
V
E
D
Y
S
H
I
E
R
Y
S
H
V
M
H
L
V
S
T
V
T
G
K
L
G
E
G
R
T
A
L
D
A
V
T
A
C
F
P
A
G
T
L
S
G
A
P
K
V
R
A
M
E
L
I
E
E
V
E
K
T
R
R
G
L
Y
G
G
V
V
G
Y
L
D
F
A
G
N
A
D
F
A
I
A
I
R
T
A
L
M
R
N
G
T
A
Y
V
Q
A
G
G
G
V
V
A
D
S
N
G
S
Y
E
Y
N
E
A
R
N
K
A
R
A
V
L
N
A
I
A
A
A
E
--
1
PsiBlast_PDB
78.62
38%
-5
- C1 -
-
1QDL
-
TRPE_SULSO
A:
[13-418]
-----------------------------------
F
E
V
F
K
C
I
E
R
D
-
F
K
V
A
G
L
L
E
S
I
-------
R
Y
S
V
I
A
W
S
T
----
N
G
Y
---------
L
K
I
H
D
D
P
V
N
---
I
------------------------------------
L
------------------------------------
N
G
Y
L
K
D
---
L
K
L
A
D
--
I
------------
P
-
G
L
F
K
-------------------------------------
G
G
M
I
G
Y
I
S
Y
D
A
V
R
F
W
E
K
----
I
R
D
L
K
P
A
A
-
E
-
D
W
P
Y
A
E
F
F
T
P
------------
D
N
I
I
I
Y
D
------
H
N
E
G
K
V
Y
----------------------------------------------------------
V
-------
N
-
A
D
L
------
S
S
---
V
-
G
------
G
CGDI
G
E
F
K
V
S
F
Y
D
--
E
S
L
N
K
N
S
Y
E
R
I
V
S
E
S
L
E
Y
I
R
S
G
Y
I
F
Q
V
V
L
S
R
F
Y
R
Y
I
F
S
--
G
D
P
L
R
I
Y
Y
N
L
R
R
I
N
P
S
P
Y
M
F
Y
L
K
F
D
------
E
K
Y
L
I
G
S
S
P
E
--
L
L
F
R
V
--
Q
--
D
N
I
V
E
T
Y
P
I
A
G
T
R
P
R
G
A
------
D
Q
------
E
E
D
L
K
L
E
L
E
L
M
N
S
E
K
D
K
A
E
H
L
M
L
V
D
L
A
R
N
D
L
G
K
V
C
V
P
G
T
V
K
V
P
E
L
M
Y
V
E
K
Y
S
H
V
Q
H
I
V
S
K
V
I
G
T
L
K
K
K
Y
N
A
L
N
V
L
S
A
T
F
P
A
G
T
V
S
G
A
P
K
P
M
A
M
N
I
I
E
T
L
E
E
Y
K
R
G
P
Y
A
G
A
V
G
F
I
S
A
D
G
N
A
E
F
A
I
A
I
R
T
A
F
L
N
K
E
L
L
R
I
H
A
G
A
G
I
V
Y
D
S
N
P
E
S
E
Y
F
E
T
E
H
K
L
K
A
L
K
T
A
I
------
30
HHSearch
77.34
28%
16
- C1 -
-
1I7Q
3
TRPE_SERMA
A:
[6-513]
------------------
Q
L
T
L
L
K
V
Q
A
S
Y
-
R
G
-
D
P
T
T
L
F
H
Q
L
C
G
A
-
R
P
A
T
L
L
L
E
S
A
E
I
N
D
K
Q
N
L
Q
S
L
L
V
I
D
S
----
A
L
R
I
T
A
L
-
G
H
T
V
S
V
Q
A
L
T
A
N
G
---
P
A
L
L
P
L
L
D
E
A
LPPE
V
R
N
Q
A
R
PN
G
R
E
L
T
F
P
AIDAVQD
E
D
------------------------------------
A
R
L
R
S
L
S
V
F
D
A
L
R
T
--
I
L
T
L
V
D
----
S
-
P
A
D
E
R
E
A
-------------------------------------
V
M
L
G
G
L
F
A
Y
D
L
V
A
G
F
E
N
----
L
P
A
L
R
-
Q
D
-
Q
-
R
C
P
D
F
C
F
Y
L
A
------------
E
T
L
L
V
L
D
------
H
Q
R
G
S
A
R
L
Q
----------
A
S
-------
V
F
------
S
EQ
A
S
E
A
Q
R
L
Q
H
R
-
L
E
Q
L
Q
A
-
E
-------
L
-------
Q
-
Q
P
P
------
Q
P
I
P
-
H
-
Q
------
K
------
L
E
N
M
Q
L
S
--
C
N
Q
S
D
E
E
Y
G
A
V
V
S
E
L
Q
E
A
I
R
Q
G
E
I
F
Q
V
V
P
S
R
R
F
S
L
P
C
P
---
A
P
L
G
P
Y
Q
T
L
K
D
N
N
P
S
P
Y
M
F
F
M
Q
D
D
------
D
F
T
L
F
G
A
S
P
E
--
S
A
L
K
Y
--
D
AG
N
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
------
R
A
DGSLD
L
D
L
D
S
R
I
E
L
E
M
R
T
D
H
K
E
L
A
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
Q
A
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
F
V
M
H
L
V
S
R
V
V
G
T
L
R
A
D
L
D
V
L
H
A
Y
Q
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
A
L
R
S
T
R
R
G
S
Y
G
G
R
V
G
Y
F
T
A
V
R
N
L
D
T
C
I
V
I
R
S
A
Y
V
E
D
G
H
R
T
V
Q
A
G
A
G
V
V
Q
D
S
I
P
E
R
E
A
D
E
T
R
N
K
A
R
A
V
L
R
A
I
A
T
A
H
--
32
HHSearch
76.61
32%
-14
- C1 -
-
5KCK
2
?
A:
[11-449]
------------------------------
V
L
-
S
P
I
L
A
Y
M
R
L
K
G
---
Q
H
K
V
I
L
E
S
I
P
-----
A
R
F
S
I
L
A
Y
N
P
----
V
F
E
I
K
F
E
-
N
G
V
L
Y
Q
N
G
Q
-----------------------------------------------------------------------------------
V
I
D
R
D
P
L
D
F
L
Y
E
--
V
I
H
K
S
Q
----
H
-
H
S
E
L
P
F
G
-------------------------------------
G
G
A
I
G
F
V
G
Y
D
M
I
S
L
Y
E
E
----
I
G
Q
I
P
-
E
D
T
I
-
G
T
P
D
M
H
F
F
V
Y
------------
E
S
Y
M
V
F
D
------
H
K
K
E
K
I
H
V
I
----------
E
D
-------
A
L
YSERS
Q
E
A
L
E
K
-------
S
-
L
N
Q
V
L
E
-
E
-------
L
-------
R
-
I
P
A
------
P
N
EFE
D
-
L
------
D
------
L
S
P
L
D
F
K
--
P
H
I
A
P
H
K
F
E
G
M
V
E
T
A
R
D
L
I
R
N
G
D
M
F
Q
C
V
L
S
Q
R
F
S
A
E
V
T
--
G
N
P
F
D
F
Y
R
N
L
R
V
T
N
P
S
N
Y
L
Y
F
Y
D
F
G
------
D
Y
Q
I
I
G
A
S
P
E
--
S
L
V
S
V
--
K
--
N
G
I
V
T
T
N
P
I
A
---------------------
E
E
D
K
A
L
A
T
D
L
L
S
D
E
K
E
T
A
E
H
R
M
L
V
D
L
G
R
N
D
I
G
R
I
S
E
T
T
S
V
Q
V
T
K
Y
M
E
V
E
L
F
R
Y
V
M
H
L
T
S
V
V
K
G
R
L
L
P
E
L
T
A
M
D
A
L
K
A
T
L
P
A
G
T
V
S
G
A
P
K
I
R
A
M
R
R
I
Y
E
L
E
T
E
K
R
G
V
Y
A
G
A
I
G
Y
L
S
A
T
G
D
M
D
L
A
I
A
I
R
T
M
I
L
K
N
Q
R
A
Y
V
Q
A
G
A
G
I
V
Y
D
S
I
A
Q
N
E
Y
Q
E
T
I
N
K
A
K
S
M
T
R
--------
25
HHSearch
73.39
26%
-6
- C1 -
-
1K0E
1
PABB_ECOLI
B:
[3-452]
----------------
T
L
S
P
A
V
I
--
T
L
L
W
-
R
Q
D
A
A
E
F
Y
F
S
R
L
S
H
--
L
P
W
A
M
L
L
H
S
G
Y
A
D
H
P
Y
S
R
F
D
I
V
V
A
E
P
----
I
C
T
L
T
T
F
-
G
K
E
T
V
V
S
E
S
E
K
-------------------------------------------------------------------------------
R
T
T
T
T
D
D
P
L
Q
V
L
Q
Q
--
V
L
D
R
A
D
IRPT
H
-
N
E
D
L
P
F
Q
-------------------------------------
G
G
A
L
G
L
F
G
Y
D
L
G
R
R
F
E
S
----
L
P
E
I
A
-
E
Q
D
I
-
V
L
P
D
M
A
V
G
I
Y
------------
D
W
A
L
I
V
D
------
H
Q
R
H
T
V
S
L
L
----------
S
H
-------
N
D
------
V
N
A
---------
R
-
R
A
W
L
E
S
-
Q
-------
Q
-------
F
---
S
------
P
Q
---
E
-
D
------
F
------
T
L
T
S
D
W
Q
--
S
N
M
T
R
E
Q
Y
G
E
K
F
R
Q
V
Q
E
Y
L
H
S
G
D
C
Y
Q
V
N
L
A
Q
R
F
H
A
T
Y
S
--
G
D
E
W
Q
A
F
L
Q
L
N
Q
A
N
R
A
P
F
S
A
F
L
R
L
E
------
Q
G
A
I
L
S
L
S
P
E
--
R
F
I
L
C
--
D
--
N
S
E
I
Q
T
R
-------------------------------------
A
K
D
R
A
E
N
L
M
I
V
D
L
M
R
N
D
I
G
R
V
A
V
A
G
S
V
K
V
P
E
--------------
S
T
I
T
A
Q
L
P
E
Q
L
H
A
S
D
L
L
R
A
A
F
P
G
G
S
I
T
G
A
P
K
V
R
A
M
E
I
I
D
E
L
E
P
Q
R
R
N
A
W
C
G
S
I
G
Y
L
S
F
C
G
N
M
D
T
S
I
T
I
R
T
L
T
A
I
N
G
Q
I
F
C
S
A
G
G
G
I
V
A
D
S
Q
E
E
A
E
Y
Q
E
T
F
D
K
V
N
R
I
L
K
Q
L
E
-----
26
HHSearch
73.23
26%
-2
- C1 -
-
1K0E
2
PABB_ECOLI
A:
[3-452]
----------------
T
L
S
P
A
V
I
--
T
L
L
W
-
R
Q
D
A
A
E
F
Y
F
S
R
L
S
H
--
L
P
W
A
M
L
L
H
S
G
Y
A
D
H
P
Y
S
R
F
D
I
V
V
A
E
P
----
I
C
T
L
T
T
F
-
G
K
E
T
V
V
S
E
S
E
K
-------------------------------------------------------------------------------
R
T
T
T
T
D
D
P
L
Q
V
L
Q
Q
--
V
L
D
R
A
D
IRPT
H
-
N
E
D
L
P
F
Q
-------------------------------------
G
G
A
L
G
L
F
G
Y
D
L
G
R
R
F
E
S
----
L
P
E
I
A
-
E
Q
D
I
-
V
L
P
D
M
A
V
G
I
Y
------------
D
W
A
L
I
V
D
------
H
Q
R
H
T
V
S
L
L
----------
S
H
-------
N
D
------
V
N
A
---------
R
-
R
A
W
L
E
S
-
Q
-------
Q
-------
F
---
S
------
P
Q
---
E
-
D
------
F
------
T
L
T
S
D
W
Q
--
S
N
M
T
R
E
Q
Y
G
E
K
F
R
Q
V
Q
E
Y
L
H
S
G
D
C
Y
Q
V
N
L
A
Q
R
F
H
A
T
Y
S
--
G
D
E
W
Q
A
F
L
Q
L
N
Q
A
N
R
A
P
F
S
A
F
L
R
L
E
------
Q
G
A
I
L
S
L
S
P
E
--
R
F
I
L
C
--
D
--
N
S
E
I
Q
T
R
P
I
K
G
T
L
P
R
--------------------------
A
N
S
A
K
D
R
A
E
N
L
M
I
V
D
L
M
R
N
D
I
G
R
V
A
V
A
G
S
V
K
V
P
E
L
F
V
V
E
P
F
P
A
V
H
H
L
V
S
T
I
T
A
Q
L
P
E
Q
L
H
A
S
D
L
L
R
A
A
F
P
G
G
S
I
T
G
A
P
K
V
R
A
M
E
I
I
D
E
L
E
P
Q
R
R
N
A
W
C
G
S
I
G
Y
L
S
F
C
G
N
M
D
T
S
I
T
I
R
T
L
T
A
I
N
G
Q
I
F
C
S
A
G
G
G
I
V
A
D
S
Q
E
E
A
E
Y
Q
E
T
F
D
K
V
N
R
I
L
K
Q
L
E
-----
27
HHSearch
72.89
24%
1
- C1 -
-
4GRH
5
?
A:
[4-454]
-----------------
G
T
H
A
P
L
I
H
P
L
P
H
-
P
----
I
D
L
L
A
L
Q
Q
H
D
P
A
R
F
P
L
L
M
E
S
T
A
S
---
Q
G
R
W
S
L
L
L
V
A
Q
----
G
D
G
L
R
L
D
-
A
D
G
Q
V
R
D
Q
H
---------------------------------------------------------------------------------
D
L
V
Q
P
G
T
F
L
Q
A
L
D
R
--
A
W
Q
H
E
R
LSHD
G
-
S
H
S
L
P
F
R
-------------------------------------
G
G
W
A
L
M
L
D
Y
E
V
A
S
Q
I
E
P
----
V
L
P
A
R
-
A
R
G
D
-
G
R
P
T
A
L
A
L
R
C
------------
P
A
A
V
L
H
D
------
H
H
N
E
A
S
F
V
I
----------
A
E
-------
A
G
E
Q
----
A
-----------
L
-
L
D
A
L
V
A
-
L
-------
A
-------
S
-
A
A
L
------
P
E
A--
G
-
Q
------
G
------
W
Q
P
P
Q
A
V
--
G
E
D
A
P
Q
R
F
T
D
G
V
R
R
V
I
E
Y
L
R
A
G
D
V
F
Q
V
N
L
S
R
R
W
N
A
Q
F
A
AP
V
S
P
Q
A
L
Y
A
Q
L
R
R
A
N
P
A
P
F
A
G
L
F
S
A
H
------
G
R
H
V
V
S
S
S
P
E
--
R
L
V
S
V
--
H
--
A
G
H
A
Q
T
R
P
I
A
G
T
R
P
R
F
E
------
G
-------
D
D
-------------
E
R
A
E
H
V
M
L
I
D
L
E
R
N
D
L
G
R
I
C
L
P
G
T
V
V
V
D
E
L
M
T
V
E
S
Y
A
H
V
H
H
I
V
S
N
V
S
G
H
L
R
P
E
V
T
P
G
E
V
I
A
A
T
F
P
G
G
T
I
T
G
C
P
K
V
R
C
M
Q
I
I
S
E
L
E
Q
V
P
R
G
A
Y
T
G
A
F
G
W
L
N
R
D
G
D
L
D
L
N
I
L
I
R
T
A
E
V
D
G
H
E
V
S
F
R
T
G
A
G
I
V
V
D
S
D
P
D
K
E
L
D
E
T
R
A
K
A
R
G
L
L
R
A
L
G
-----
5
PsiBlast_PDB
71.10
32%
10
- C1 -
-
1I7S
1
TRPE_SERMA
A:
[145-505]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
G
L
F
A
Y
D
L
V
A
G
F
E
N
----
L
P
A
L
R
-
Q
D
-
Q
-
R
C
P
D
F
C
F
Y
L
A
------------
E
T
L
L
V
L
D
HQRG
S
A
R
L
Q
A
S
V
F
S
E
----------
Q
A
-------
S
E
------
A
Q
----------
R
-
L
Q
H
R
L
E
-
Q
-------
L
-------
Q
-
A
E
L
------
Q
Q
---
P
-
P
Q
P
I
P
H
Q
K
------
L
E
N
M
Q
L
S
--
C
N
Q
S
D
E
E
Y
G
A
V
V
S
E
L
Q
E
A
I
R
Q
G
E
I
F
Q
V
-
V
P
S
R
R
F
S
L
P
C
--
P
A
P
L
G
P
Y
Q
T
L
K
D
N
N
P
S
P
Y
M
F
F
M
Q
D
D
------
D
F
T
L
F
G
A
S
P
E
SA
L
K
Y
D
A
--
G
--
N
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
RADGSL
D
L
------
D
L
D
S
R
I
E
L
E
M
R
T
D
H
K
E
L
A
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
Q
A
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
F
V
M
H
L
V
S
R
V
V
G
T
L
R
A
D
L
D
V
L
H
A
Y
Q
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
A
L
R
S
T
R
R
G
S
Y
G
G
R
V
G
Y
F
T
A
V
R
N
L
D
T
C
I
V
I
R
S
A
Y
V
E
D
G
H
R
T
V
Q
A
G
A
G
V
V
Q
D
S
I
P
E
R
E
A
D
E
T
R
N
K
A
R
A
V
----------
48
Fugue
70.82
25%
-23
- C1 -
-
1K0E
2
PABB_ECOLI
A:
[3-453]
------------------
T
L
S
P
A
V
I
T
L
L
W
-
R
Q
-
D
A
A
E
F
Y
F
S
R
L
S
H
-
L
P
W
A
M
L
L
H
S
G
Y
A
D
H
P
Y
S
R
F
D
I
V
V
A
E
P
----
I
C
T
L
T
T
F
-
G
K
E
T
V
V
S
E
S
E
K
R
T
---
T
------------------------------------
T
------------------------------------
T
D
D
P
L
Q
V
L
Q
Q
V
L
D
R
A
D
I
R
P
T
-
H
----
N
-
E
D
-
L
P
F
Q
-------------------------------------
G
G
A
L
G
L
F
G
Y
D
L
G
R
R
F
E
S
L---
P
E
I
A
E
-
Q
D
-
I
-
V
L
P
D
M
A
V
G
I
Y
------------
D
W
A
L
I
V
D
------
H
Q
R
H
T
V
S
L
L
----------
S
H
-------
N
D
------
V
-----------
N
-
A
R
R
A
W
L
-
E
-------
S
-------
Q
-
Q
F
S
------
P
Q
---
E
-
D
------
F
------
T
L
T
S
D
W
Q
--
S
N
M
T
R
E
Q
Y
G
E
K
F
R
Q
V
Q
E
Y
L
H
S
G
D
C
Y
Q
V
N
L
A
Q
R
F
H
A
T
Y
S
--
G
D
E
W
Q
A
F
L
Q
L
N
Q
A
N
R
A
P
F
S
A
F
L
R
L
E
------
Q
G
A
I
L
S
L
S
P
E
--
R
F
I
L
C
--
D
--
N
S
E
I
Q
T
R
P
I
K
G
T
L
P
R
A
N
------
S
--------------------
A
K
D
R
A
E
N
L
M
I
V
D
L
M
R
N
D
I
G
R
V
A
V
A
G
S
V
K
V
P
E
L
F
V
V
E
P
F
P
A
V
H
H
L
V
S
T
I
T
A
Q
L
P
E
Q
L
H
A
S
D
L
L
R
A
A
F
P
G
G
S
I
T
G
A
P
K
V
R
A
M
E
I
I
D
E
L
E
P
Q
R
R
N
A
W
C
G
S
I
G
Y
L
S
F
C
G
N
M
D
T
S
I
T
I
R
T
L
T
A
I
N
G
Q
I
F
C
S
A
G
G
G
I
V
A
D
S
Q
E
E
A
E
Y
Q
E
T
F
D
K
V
N
R
I
L
K
Q
L
E
K
----
51
Fugue
70.16
25%
6
- C1 -
-
1I1Q
1
TRPE_SALTY
A:
[5-516]
------
K
P
T
L
E
L
L
T
C
D
A
A
Y
R
E
------------
N
P
T
A
L
F
H
Q
V
C
G
D
-
R
P
A
T
L
L
L
E
S
A
D
I
D
S
K
D
D
L
K
S
L
L
L
V
D
S
----
A
L
R
I
T
A
L
G
D
T
V
T
I
Q
A
L
S
D
N
G
A
---
S
------------------------------------
L
------------------------------------
L
P
L
L
D
T
A
L
P
A
G
V
E
N
--
D
V
L
P
-
A
----
G
-
R
V
-
L
R
F
P
P
V
S
PLLD
E
N
A
R
L
C
SLSVFD
A
F
R
L
L
Q
G
V
V
N
I
P
TQEREA
M
F
F
G
G
L
F
A
Y
D
L
V
A
G
F
E
A
----
L
P
H
L
E
-
A
G
-
N
-
N
C
P
D
Y
C
F
Y
L
A
------------
E
T
L
M
V
I
D
------
H
Q
K
K
S
T
R
I
Q
----------
A
S
L
FTAS
D
R
E
K
------
Q
-----------
R
-
L
N
A
R
L
A
-
Y
-------
L
-------
S
-
Q
Q
L
T
QPAP
P
L
P
---
V
-
T
------
P
------
V
P
D
M
R
C
E
--
C
N
Q
S
D
D
A
F
G
A
V
V
R
Q
L
Q
K
A
I
R
A
G
E
I
F
Q
V
V
P
S
R
R
F
S
L
P
C
P
---
S
P
L
A
A
Y
Y
V
L
K
K
S
N
P
S
P
Y
M
F
F
M
Q
D
N
------
D
F
T
L
F
G
A
S
P
E
--
S
S
L
K
Y
D
A
A
--
S
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
RADGTL
D
R
------
D
L
D
S
R
I
E
L
D
M
R
T
D
H
K
E
L
S
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
T
P
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
Y
V
M
H
L
V
S
R
V
V
G
E
L
R
H
D
L
D
A
L
H
A
Y
R
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
D
A
E
G
Q
R
R
G
S
Y
G
G
A
V
G
Y
F
T
A
H
G
D
L
D
T
C
I
V
I
R
S
A
L
V
E
N
G
I
A
T
V
Q
A
G
A
G
I
V
L
D
S
V
P
Q
S
E
A
D
E
T
R
N
K
A
R
A
V
L
R
A
I
A
T
A
H
H
A
21
PsiBlast_CBE
67.73
32%
12
- C1 -
-
1I7S
1
TRPE_SERMA
C:
[145-505]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
G
L
F
A
Y
D
L
V
A
G
F
E
N
----
L
P
A
L
R
-
Q
D
-
Q
-
R
C
P
D
F
C
F
Y
L
A
------------
E
T
L
L
V
L
D
HQRGSA
R
L
Q
A
S
V
F
S
E
----------
Q
A
-------
S
E
------
A
Q----------
R
-
L
Q
H
R
L
E
-
Q
-------
L
-------
Q
-
A
E
L
------
Q
Q
---
P
-
P
QPIPHQ
K
------
L
E
N
M
Q
L
S
--
C
N
Q
S
D
E
E
Y
G
A
V
V
S
E
L
Q
E
A
I
R
Q
G
E
I
F
Q
V
-
V
P
S
R
R
F
S
L
P
C
--
P
A
P
L
G
P
Y
Q
T
L
K
D
N
N
P
S
P
Y
M
F
F
M
Q
D
D
------
D
F
T
L
F
G
A
S
P
E
SA
L
K
Y
D
A
--
G
--
N
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
RADGSL
D
L
------
D
L
D
S
R
I
E
L
E
M
R
T
D
H
K
E
L
A
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
Q
A
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
F
V
M
H
L
V
S
R
V
V
G
T
L
R
A
D
L
D
V
L
H
A
Y
Q
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
A
L
R
S
T
R
R
G
S
Y
G
G
R
V
G
Y
F
T
A
V
R
N
L
D
T
C
I
V
I
R
S
A
Y
V
E
D
G
H
R
T
V
Q
A
G
A
G
V
V
Q
D
S
I
P
E
R
E
A
D
E
T
R
N
K
A
R
A
V
----------
33
HHSearch
67.45
25%
24
- C1 -
-
1I1Q
1
TRPE_SALTY
A:
[7-514]
-------------------
T
L
E
L
L
T
C
D
A
A
-
Y
R
E
N
P
T
A
L
F
H
Q
V
C
G
D
-
R
P
A
T
L
L
L
E
S
A
D
I
D
S
K
D
D
L
K
S
L
L
L
V
D
S
----
A
L
R
I
T
A
L
-
G
D
T
V
T
I
Q
A
L
S
D
N
G
---
A
------------------------------------
S
L
L
P
L
L
D
T
A
LPAG
V
E
N
D
V
L
PA
G
R
V
L
R
F
P
P
V
S
PLLD
E
N
A
R
L
C
S
L
S
V
F
D
A
F
R
L
--
L
Q
G
V
V
N
----
I
-
P
T
Q
E
R
E
A
-------------------------------------
M
F
F
G
G
L
F
A
Y
D
L
V
A
G
F
E
A
----
L
P
H
L
E
-
A
G
-
N
-
N
C
P
D
Y
C
F
Y
L
A
------------
E
T
L
M
V
I
D
------
H
Q
K
K
S
T
R
I
Q
----------
A
S
-------
L
F
TAS
D
--
R
-----------
E
-
K
Q
R
L
N
A
-
R
-------
L
A
Y
L
S
Q
Q
L
T
-
Q
P
A
------
P
P
L
P
-
V
-
T
------
P
------
V
P
D
M
R
C
E
--
C
N
Q
S
D
D
A
F
G
A
V
V
R
Q
L
Q
K
A
I
R
A
G
E
I
F
Q
V
V
P
S
R
R
F
S
L
P
C
P
---
S
P
L
A
A
Y
Y
V
L
K
K
S
N
P
S
P
Y
M
F
F
M
Q
D
N
------
D
F
T
L
F
G
A
S
P
E
--
S
S
L
K
Y
--
D
AA
S
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
------
R
A
DGTLD
R
D
L
D
S
R
I
E
L
D
M
R
T
D
H
K
E
L
S
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
T
P
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
Y
V
M
H
L
V
S
R
V
V
G
E
L
R
H
D
L
D
A
L
H
A
Y
R
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
D
A
E
G
Q
R
R
G
S
Y
G
G
A
V
G
Y
F
T
A
H
G
D
L
D
T
C
I
V
I
R
S
A
L
V
E
N
G
I
A
T
V
Q
A
G
A
G
I
V
L
D
S
V
P
Q
S
E
A
D
E
T
R
N
K
A
R
A
V
L
R
A
I
A
T
A
H
--
37
HHSearch
66.60
20%
-80
* C1 *
-
2FN0
-
?
A:
[20-436]
------------------------------
L
P
-
T
I
S
G
V
L
R
Q
F
A
E
E
--
E
C
Y
V
Y
------
E
R
P
P
C
W
Y
L
G
K
G
C
Q
A
----
R
L
H
I
N
A
D
-
G
T
Q
A
T
F
I
D
D
A
G
E
------------------------------------------------------------------------------
Q
K
W
A
V
D
S
I
A
D
C
A
R
R
--
F
M
A
H
-
P
---------
Q
V
K
G
-------------------------------------
R
R
V
Y
G
Q
V
G
F
N
F
A
A
H
A
R
G
----
I
A
F
N
A
----
G
-
E
W
P
L
L
T
L
T
V
P
------------
R
E
E
L
I
F
E
------
K
G
N
--
V
T
V
Y
----------
A
D
-------------------------------------------------------------------------------------
A
P
L
A
V
D
--
T
A
L
N
G
E
A
Y
K
Q
Q
V
A
R
A
V
A
E
I
R
R
G
E
Y
V
K
V
I
V
S
R
A
I
P
L
P
S
R
--
I
D
M
P
A
T
L
L
Y
G
R
Q
A
N
T
P
V
R
S
F
M
F
R
Q
E
------
G
R
E
A
L
G
F
S
P
E
--
L
V
M
S
V
--
T
--
G
N
K
V
V
T
E
P
L
A
G
T
R
D
R
M
G
------
N
P
------
E
H
N
K
A
K
E
A
E
L
L
H
D
S
K
E
V
L
E
H
I
L
S
V
K
E
A
I
A
E
L
E
A
V
C
L
P
G
S
V
V
V
E
D
L
M
S
V
R
Q
R
G
S
V
Q
H
L
G
S
G
V
S
G
Q
L
A
E
N
K
D
A
W
D
A
F
T
V
L
F
P
S
I
T
A
S
G
I
P
K
N
A
A
L
N
A
I
M
Q
I
E
K
T
P
R
E
L
Y
S
G
A
I
L
L
L
D
D
-
T
R
F
D
A
A
L
V
L
R
S
V
F
Q
D
S
Q
R
C
W
I
Q
A
G
A
G
I
I
A
Q
S
T
P
E
R
E
L
T
E
T
R
E
K
L
A
S
I
A
P
Y
L
M
-----
22
PsiBlast_CBE
66.29
32%
11
- C1 -
-
1I7Q
3
TRPE_SERMA
C:
[145-505]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
G
L
F
A
Y
D
L
V
A
G
F
E
N
----
L
P
A
L
R
-
Q
D
-
Q
-
R
C
P
D
F
C
F
Y
L
A
------------
E
T
L
L
V
L
D
HQRGSA
R
L
Q
A
S
V
F
S
E
----------
Q
A
-------
S
E
------
A
Q----------
R
-
L
Q
H
R
L
E
-
Q
-------
L
-------
Q
-
A
E
L
------
Q
Q
---
P
-
P
QPIPHQ
K
------
L
E
N
M
Q
L
S
--
C
N
Q
S
D
E
E
Y
G
A
V
V
S
E
L
Q
E
A
I
R
Q
G
E
I
F
Q
V
-
V
P
S
R
R
F
S
L
P
C
--
P
A
P
L
G
P
Y
Q
T
L
K
D
N
N
P
S
P
Y
M
F
F
M
Q
D
D
------
D
F
T
L
F
G
A
S
P
E
SA
L
K
Y
D
A
--
G
--
N
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
RADGSL
D
L
------
D
L
D
S
R
I
E
L
E
M
R
T
D
H
K
E
L
A
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
Q
A
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
F
V
M
H
L
V
S
R
V
V
G
T
L
R
A
D
L
D
V
L
H
A
Y
Q
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
A
L
R
S
T
R
R
G
S
Y
G
G
R
V
G
Y
F
T
A
V
R
N
L
D
T
C
I
V
I
R
S
A
Y
V
E
D
G
H
R
T
V
Q
A
G
A
G
V
V
Q
D
S
I
P
E
R
E
A
D
E
T
R
N
K
A
R
A
V
----------
4
PsiBlast_PDB
65.15
32%
14
- C1 -
-
1I7Q
3
TRPE_SERMA
A:
[145-505]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
G
L
F
A
Y
D
L
V
A
G
F
E
N
----
L
P
A
L
R
-
Q
D
-
Q
-
R
C
P
D
F
C
F
Y
L
A
------------
E
T
L
L
V
L
D
HQRG
S
A
R
L
Q
A
S
V
F
S
E
----------
Q
A
-------
S
E
------
A
Q
----------
R
-
L
Q
H
R
L
E
-
Q
-------
L
-------
Q
-
A
E
L
------
Q
Q
---
P
-
P
QPI
P
H
Q
K
------
L
E
N
M
Q
L
S
--
C
N
Q
S
D
E
E
Y
G
A
V
V
S
E
L
Q
E
A
I
R
Q
G
E
I
F
Q
V
-
V
P
S
R
R
F
S
L
P
C
--
P
A
P
L
G
P
Y
Q
T
L
K
D
N
N
P
S
P
Y
M
F
F
M
Q
D
D
------
D
F
T
L
F
G
A
S
P
E
SA
L
K
Y
D
A
--
G
--
N
R
Q
I
E
I
Y
P
I
A
G
T
R
P
R
G
R
RADGSL
D
L
------
D
L
D
S
R
I
E
L
E
M
R
T
D
H
K
E
L
A
E
H
L
M
L
V
D
L
A
R
N
D
L
A
R
I
C
Q
A
G
S
R
Y
V
A
D
L
T
K
V
D
R
Y
S
F
V
M
H
L
V
S
R
V
V
G
T
L
R
A
D
L
D
V
L
H
A
Y
Q
A
C
M
N
M
G
T
L
S
G
A
P
K
V
R
A
M
Q
L
I
A
A
L
R
S
T
R
R
G
S
Y
G
G
R
V
G
Y
F
T
A
V
R
N
L
D
T
C
I
V
I
R
S
A
Y
V
E
D
G
H
R
T
V
Q
A
G
A
G
V
V
Q
D
S
I
P
E
R
E
A
D
E
T
R
N
K
A
R
A
V
----------
6
PsiBlast_PDB
64.91
29%
17
- C1 -
-
1K0E
2
PABB_ECOLI
A:
[44-452]
--------------------------------------------------------------
S
R
F
D
I
V
V
A
E
P
I
C
T
L
T
T
F
G
K
E
T
-
V
V
S
E
S
E
K
R
T
T
T
T
D
D
P
L
Q
------------------------------------
V
------------------------------------
L
Q
Q
V
L
D
R
A
-----
D
--
I
R
P
T
-
H
----
N
-
E
D
-
L
P
F
Q
-------------------------------------
G
G
A
L
G
L
F
G
Y
D
L
G
R
R
F
E
S
----
L
P
E
I
A
-
E
Q
-
D
I
V
L
P
D
M
A
V
G
I
Y
------------
D
W
A
L
I
V
D
------
H
Q
R
H
T
V
S
L
L
S
HND
V
N
A
R
R
A
W
L
-------
E
S
------
Q
-----------
Q
-
F
S
P
Q
E
D
F
T
-------
L
-------
T
-
S
D
W
------
Q
S
---
N
--------------------------
M
T
R
E
Q
Y
G
E
K
F
R
Q
V
Q
E
Y
L
H
S
G
D
C
Y
Q
V
N
L
A
Q
R
F
H
A
T
Y
S
--
G
D
E
W
Q
A
F
L
Q
L
N
Q
A
N
R
A
P
F
S
A
F
L
R
L
E
------
Q
G
A
I
L
S
L
S
P
E
--
R
F
I
L
C
--
D
--
N
S
E
I
Q
T
R
P
I
K
G
T
L
P
R
--------------------------
A
N
S
A
K
D
R
A
E
N
L
M
I
V
D
L
M
R
N
D
I
G
R
V
A
V
A
G
S
V
K
V
P
E
L
F
V
V
E
P
F
P
A
V
H
H
L
V
S
T
I
T
A
Q
L
P
E
Q
L
H
A
S
D
L
L
R
A
A
F
P
G
G
S
I
T
G
A
P
K
V
R
A
M
E
I
I
D
E
L
E
P
Q
R
R
N
A
W
C
G
S
I
G
Y
L
S
F
C
G
N
M
D
T
S
I
T
I
R
T
L
T
A
I
N
G
Q
I
F
C
S
A
G
G
G
I
V
A
D
S
Q
E
E
A
E
Y
Q
E
T
F
D
K
V
---
N
R
I
L
K
Q
L
E
--
2
PsiBlast_PDB
63.70
35%
14
- C1 -
-
5KCK
2
?
A:
[81-439]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
Q
H
H
S
ELPFG--------------------------------
G
G
A
I
G
F
V
G
Y
D
M
I
S
L
Y
E
E
IGQI
P
E
D
T
I
-
G
T
-
P
-
D
M
H
F
F
V
Y
E
S
Y
M
V
F
DHKKE
K
I
H
V
I
E
D
A
L
Y
S
------
E
R
S
Q
E
A
L
----------------------
E
------
K
-----------
S
-
L
N
Q
V
L
E
-
E
-------
L
-------
R
I
P
A
P
------
N
E
---
F
-
E
------
D
------
L
D
L
S
P
L
D
FK
P
H
I
A
P
H
K
F
E
G
M
V
E
T
A
R
D
L
I
R
N
G
D
M
F
Q
C
V
L
S
Q
R
F
S
A
E
V
T
--
G
N
P
F
D
F
Y
R
N
L
R
V
T
N
P
S
N
Y
L
Y
F
Y
D
F
G
------
D
Y
Q
I
I
G
A
S
P
E
--
S
L
V
S
V
--
K
--
N
G
I
V
T
T
N
P
I
A
---------------------
E
E
D
K
A
L
A
T
D
L
L
S
D
E
K
E
T
A
E
H
R
M
L
V
D
L
G
R
N
D
I
G
R
I
S
E
T
T
S
V
Q
V
T
K
Y
M
E
V
E
L
F
R
Y
V
M
H
L
T
S
V
V
K
G
R
L
L
P
E
L
T
A
M
D
A
L
K
A
T
L
P
A
G
T
V
S
G
A
P
K
I
R
A
M
R
R
I
Y
E
L
E
T
E
K
R
G
V
Y
A
G
A
I
G
Y
L
S
A
T
G
D
M
D
L
A
I
A
I
R
T
M
I
L
K
N
Q
R
A
Y
V
Q
A
G
A
G
I
V
Y
D
S
I
A
Q
N
E
Y
Q
E
------------------
7
PsiBlast_PDB
63.04
29%
21
- C1 -
-
1K0G
1
PABB_ECOLI
A:
[44-452]
--------------------------------------------------------------
S
R
F
D
I
V
V
A
E
P
I
C
T
L
T
T
F
G
K
E
T
-
V
V
S
E
S
E
K
R
T
T
T
T
D
D
P
L
Q
------------------------------------
V
------------------------------------
L
Q
Q
V
L
D
R
A
-----
D
--
I
R
P
T
-
H
----
N
-
E
D
-
L
P
F
Q
-------------------------------------
G
G
A
L
G
L
F
G
Y
D
L
G
R
R
F
E
S
----
L
P
E
I
A
-
E
Q
-
D
I
V
L
P
D
M
A
V
G
I
Y
------------
D
W
A
L
I
V
D
------
H
Q
R
H
T
V
S
L
L
S
HND
V
N
A
R
R
A
W
L
-------
E
S
------
Q
-----------
Q
-
F
S
P
Q
E
D
F
T
-------
L
-------
T
-
S
D
W
------
Q
S
---
N
--------------------------
M
T
R
E
Q
Y
G
E
K
F
R
Q
V
Q
E
Y
L
H
S
G
D
C
Y
Q
V
N
L
A
Q
R
F
H
A
T
Y
S
--
G
D
E
W
Q
A
F
L
Q
L
N
Q
A
N
R
A
P
F
S
A
F
L
R
L
E
------
Q
G
A
I
L
S
L
S
P
E
--
R
F
I
L
C
--
D
--
N
S
E
I
Q
T
R
P
I
K
------------------------------------
D
R
A
E
N
L
M
I
V
D
L
M
R
N
D
I
G
R
V
A
V
A
G
S
V
K
V
P
E
L
F
V
---------
L
V
S
T
I
T
A
Q
L
P
E
Q
L
H
A
S
D
L
L
R
A
A
F
P
G
G
S
I
T
G
A
P
K
V
R
A
M
E
I
I
D
E
L
E
P
Q
R
R
N
A
W
C
G
S
I
G
Y
L
S
F
C
G
N
M
D
T
S
I
T
I
R
T
L
T
A
I
N
G
Q
I
F
C
S
A
G
G
G
I
V
A
D
S
Q
E
E
A
E
Y
Q
E
T
F
D
K
V
---
N
R
I
L
K
Q
L
E
--
3
PsiBlast_PDB
60.48
41%
18
- C1 -
-
5CWA
3
TRPE_MYCTO
A:
[234-498]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
E
E
Y
G
A
I
V
E
Y
L
V
D
Q
I
A
A
G
E
A
F
Q
V
V
P
S
Q
R
F
E
M
D
T
D
--
V
D
P
I
D
V
Y
R
I
L
R
V
T
N
P
S
P
Y
M
Y
L
L
Q
V
P
N
SDGAV
D
F
S
I
V
G
S
S
P
E
--
A
L
V
T
V
--
H
--
E
G
W
A
T
T
H
P
I
A
G
T
R
W
R
G
R
------
T
D
------
D
E
D
V
L
L
E
K
E
L
L
A
D
D
K
E
R
A
E
H
L
M
L
V
D
L
G
R
N
D
L
G
R
V
C
T
P
G
T
V
R
V
E
D
Y
S
H
I
E
R
Y
S
H
V
M
H
L
V
S
T
V
T
G
K
L
G
E
G
R
T
A
L
D
A
V
T
A
C
F
P
A
G
T
L
S
G
A
P
K
V
R
A
M
E
L
I
E
E
V
E
K
T
R
R
G
L
Y
G
G
V
V
G
Y
L
D
F
A
G
N
A
D
F
A
I
A
I
R
T
A
L
M
R
N
G
T
A
Y
V
Q
A
G
G
G
V
V
A
D
S
N
G
S
Y
E
Y
N
E
A
R
N
K
A
R
A
V
----------