@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMN1: (2017-11-09 )
MALFNSTSWAKYSVIAASLAGVMMLGGCAKKEEHTTTTLNIGYQKYGILPILKARGDLEKALKDQGVQVKWVEFPAGPQLLEGLNVGSVSLGEAGEAPPIFAQAANPNLVYVANQPAAPKAEALLVQKDSPIQSIKDLKGKRVALNKGSNVHYLLLKVLEANHLSLSDIQPVYLPPSDARAAFEKEAVDAWVIWDPFFAAAEHQIQARVLATGENLVSNHQFYLADRKFAENNPKVLNTVVQTLNQTTQWVSTHQDEAAKLLEKPTALEFDVLKTSISRMGFGVQPISDKVAQEQQYVADAFYAQKLIPNKLTIQEAILKLK
Atome Classification :
(20 SA)
.........10........20........-30........40...--.-.---.---.---.--------50.-..-.....60........70....---.-----...80........90........100..--.....-110.......120.-......--130.-.....-.140....-.--------------------------..150.....--..160.......170...-....180------------------------.........190---------------.-..-.....200---......-----.--.210.--.---------.---.--.--..220.........230.......240.......250-...-.....260....-.-.--.270....-..-.--280-.-.--.--.-..-----..290---------------........300....-...-310....-...320--------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MALFNSTSWA
K
Y
S
V
I
A
A
S
L
A
G
V
M
M
LGGCA-KKEEHT
T
T
T
L
N
IGYQ--K-Y---G---
I
---
L
--------
P
I
L
-KA-R
G
D
L
E
K
A
L
KDQG
V
Q
V
K
W
V
EFP---A-----
G
P
Q
L
L
E
GLNVGSVSLGEAGEAP
P
I
F
AQA--ANP
N
L
-
V
Y
V
ANQPAAPKA
E
A
-
L
L
V
QKD--S
P
I
Q
-
S
I
K
DL-KG
K
R
V
A
LN-K--------------------------GS
N
V
H
Y
L
L
L
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--
V
L
EANHLSLSDI
Q
P
V
YLP-P
S
D
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R
--------------------------
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EAV
D
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----------------
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W-
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--MG--F-G--V--Q-P
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S
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----------------
A
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A
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-LIP-N
K
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T
I
Q
E
-
A
I
L
KLK--------------------------------------------------
17
PsiBlast_CBE
100.00
45%
0
- C- -
-
2X26
1
SSUA_ECOLI
B:
[5-301]
---------------------------------------
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------------------------------------------------------
30
HHSearch
74.15
44%
12
- C1 -
-
2X26
1
SSUA_ECOLI
A:
[2-287]
------------------------------------
P
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---------------------------------------------------
21
HHSearch
73.98
43%
19
- C1 -
-
3E4R
1
?
A:
[25-313]
---------------------------------
A
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---------------------------------------------------
1
PsiBlast_PDB
73.54
45%
16
- C1 -
-
2X26
1
SSUA_ECOLI
A:
[5-284]
---------------------------------------
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------------------------------------------------------
39
Fugue
73.24
43%
23
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3E4R
1
?
A:
[25-315]
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D-------------------------------------------------
20
HHSearch
72.60
43%
17
- C1 -
-
3KSX
1
?
A:
[25-313]
---------------------------------
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---------------------------------------------------
2
PsiBlast_PDB
71.48
43%
20
- C1 -
-
3E4R
1
?
A:
[31-312]
---------------------------------------
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F
P
R
--
T
K
I
T
W
V
E
F
P
---
A
-----
G
P
Q
L
L
E
A
L
N
V
G
S
I
D
L
G
G
A
G
D
I
P
P
L
F
A
Q
A
--
A
G
A
D
L
-
L
Y
V
G
W
V
P
P
T
P
K
A
E
T
-
I
L
V
P
S
K
--
S
A
L
R
-
T
V
A
D
L
-
K
G
K
R
I
A
F
Q
-
K
--------------------------
G
S
S
A
H
N
L
L
L
R
--
V
L
A
K
S
G
L
S
M
R
D
I
T
P
L
Y
L
S
-
P
A
N
A
R
--------------------------
A
A
F
A
A
G
Q
V
D
A
W
----------------
A
-
I
W
-
D
P
W
Y
S
A
L
----
T
L
D
G
S
A
-----
R
--
L
L
A
N
G
--
E
---------
G
---
L
--
G
--
L
T
G
--
G
F
F
L
S
S
R
R
Y
A
T
A
W
G
P
F
V
Q
Q
V
M
G
T
L
N
Q
A
D
G
L
L
--
E
R
D
-
R
A
G
S
I
K
T
L
A
Q
V
S
-
G
-
L
--
P
P
A
V
V
E
R
T
-
L
A
H
R
--
P
P
--
A
-
S
--
V
--
Q
-
P
L
-----
S
A
Q
V
----------------
I
K
A
Q
Q
A
T
A
D
L
F
Y
A
Q
R
-
L
L
P
-
K
R
V
L
V
A
P
-
A
V
W
R
----------------------------------------------------
4
PsiBlast_PDB
70.57
43%
17
- C1 -
-
3KSX
1
?
A:
[31-312]
---------------------------------------
L
R
I
G
Y
Q
--
K
A
V
---
S
---
S
---
L
--------
V
L
A
-
K
Q
-
H
R
L
L
E
Q
R
F
P
R
--
T
K
I
T
W
V
E
F
P
---
A
-----
G
P
Q
L
L
E
A
L
N
V
G
S
I
D
L
G
G
A
G
D
I
P
P
L
F
A
Q
A
--
A
G
A
D
L
-
L
Y
V
G
W
V
P
P
T
P
K
A
E
T
-
I
L
V
P
S
K
--
S
A
L
R
-
T
V
A
D
L
-
K
G
K
R
I
A
F
Q
-
K
--------------------------
G
S
S
A
H
N
L
L
L
R
--
V
L
A
K
S
G
L
S
M
R
D
I
T
P
L
Y
L
S
-
P
A
N
A
R
--------------------------
A
A
F
A
A
G
Q
V
D
A
W
----------------
A
-
I
W
-
D
P
W
Y
S
A
L
----
T
L
D
G
S
A
-----
R
--
L
L
A
N
G
--
E
---------
G
---
L
--
G
--
L
T
G
--
G
F
F
L
S
S
R
R
Y
A
T
A
W
G
P
F
V
Q
Q
V
M
G
T
L
N
Q
A
D
G
L
L
--
E
R
D
-
R
A
G
S
I
K
T
L
A
Q
V
S
-
G
-
L
--
P
P
A
V
V
E
R
T
-
L
A
H
R
--
P
P
--
A
-
S
--
V
--
Q
-
P
L
-----
S
A
Q
V
----------------
I
K
A
Q
Q
A
T
A
D
L
F
Y
A
Q
R
-
L
L
P
-
K
R
V
L
V
A
P
-
A
V
W
R
----------------------------------------------------
3
PsiBlast_PDB
69.66
43%
13
- C1 -
-
3KSJ
1
?
A:
[31-312]
---------------------------------------
L
R
I
G
Y
Q
--
K
A
V
---
S
---
S
---
L
--------
V
L
A
-
K
Q
-
H
R
L
L
E
Q
R
F
P
R
--
T
K
I
T
W
V
E
F
P
---
A
-----
G
P
Q
L
L
E
A
L
N
V
G
S
I
D
L
G
G
A
G
D
I
P
P
L
F
A
Q
A
--
A
G
A
D
L
-
L
Y
V
G
W
V
P
P
T
P
K
A
E
T
-
I
L
V
P
S
K
--
S
A
L
R
-
T
V
A
D
L
-
K
G
K
R
I
A
F
Q
-
K
--------------------------
G
S
S
A
H
N
L
L
L
R
--
V
L
A
K
S
G
L
S
M
R
D
I
T
P
L
Y
L
S
-
P
A
N
A
R
--------------------------
A
A
F
A
A
G
Q
V
D
A
W
----------------
A
-
I
W
-
D
P
W
Y
S
A
L
----
T
L
D
G
S
A
-----
R
--
L
L
A
N
G
--
E
---------
G
---
L
--
G
--
L
T
G
--
G
F
F
L
S
S
R
R
Y
A
T
A
W
G
P
F
V
Q
Q
V
M
G
T
L
N
Q
A
D
G
L
L
--
E
R
D
-
R
A
G
S
I
K
T
L
A
Q
V
S
-
G
-
L
--
P
P
A
V
V
E
R
T
-
L
A
H
R
--
P
P
--
A
-
S
--
V
--
Q
-
P
L
-----
S
A
Q
V
----------------
I
K
A
Q
Q
A
T
A
D
L
F
Y
A
Q
R
-
L
L
P
-
K
R
V
L
V
A
P
-
A
V
W
R
----------------------------------------------------
40
Fugue
50.17
21%
15
- C1 -
-
3UIF
1
?
A:
[2-331]
----------------
V
E
D
L
K
V
V
R
I
A
S
V
A
-
T
N
V
G
--------
G
K
T
--
V
-
Y
---
A
---
G
---
S
--------
A
S
L
-
V
V
-
N
G
A
F
P
E
E
L
R
K
Q
G
I
K
V
E
W
V
P
A
A
MAS
V
-----
G
P
V
I
N
E
G
F
A
S
G
K
I
D
F
G
I
Y
G
D
L
P
P
I
I
L
N
A
--
S
K
P
T
V
-
Q
L
V
A
P
W
G
T
-
T
S
N
S
Y
-
L
V
V
P
K
N
--
S
T
A
K
-
S
I
K
D
L
-
K
G
K
K
I
A
L
H
-
R
--------------------------
G
R
P
W
E
L
A
F
S
N
--
L
L
Q
S
E
G
L
T
F
K
D
F
K
I
V
N
V
N
-
P
Q
V
G
A
--------------------------
A
A
L
A
S
G
T
V
D
G
F
----------------
F
S
L
F
-
D
S
Y
I
L
E
D
----
R
G
V
G
K
I
-----
I
--
W
S
T
K
T
--
A
---------
P
---
V
--
D
--
W
K
L
M
-
G
G
V
W
A
R
N
D
F
V
K
Q
N
P
E
I
T
Q
A
I
V
T
A
Y
L
K
S
V
H
W
V
--
A
Q
D
-
E
N
K
E
T
Y
I
R
E
Y
S
N
-
K
I
Y
--
P
E
S
V
N
R
R
E
-
Y
D
-
Q
--
D
N
--
V
-
S
--
W
--
R
-
Q
R
W
SPLY
D
V
A
L
----------------
Q
E
H
Y
R
K
A
V
A
Y
A
Q
A
S
G
-
L
T
R
-
T
Q
A
D
V
Q
Q
M
L
N
P
H
F
V
A
T
A
L
K
E
L
KLEGF
W
T
P
N
A
ENLY-----------------------------
38
HHSearch
47.83
21%
27
- C1 -
-
3UIF
1
?
A:
[5-308]
------------------------------------
L
K
V
V
R
I
A
S
V
--
A
-
T
---
N
---
V
---
G
G
K
T
V
Y
A
G
S
A
S
L
-
V
V
-
N
G
A
F
P
E
E
L
R
K
Q
G
I
K
V
E
W
V
P
A
A
---
M
ASV--
G
P
V
I
N
E
G
F
A
S
G
K
I
D
F
G
I
Y
G
D
L
P
P
I
I
L
N
A
--
S
K
P
T
V
-
Q
L
V
A
P
W
G
-
T
T
S
N
S
Y
-
L
V
V
P
K
N
--
S
T
A
K
-
S
I
K
D
L
-
K
G
K
K
I
A
L
H
-
R
--------------------------
G
R
P
W
E
L
A
F
S
N
--
L
L
Q
S
E
G
L
T
F
K
D
F
K
I
V
N
V
N
-
P
Q
V
G
A
--------------------------
A
A
L
A
S
G
T
V
D
G
F
----------------
F
-
S
L
F
D
S
Y
I
L
------
E
D
R
G
V
G
-----
K
--
I
I
W
S
T
--
K
---------
T
APV
D
--
W
--
K
L
M
--
G
G
V
W
A
R
N
D
F
V
K
Q
N
P
E
I
T
Q
A
I
V
T
A
Y
L
K
S
V
H
W
V
--
A
Q
D
-
E
N
K
E
T
-
Y
I
R
E
Y
S
N
K
-
I
--
Y
P
E
S
V
N
R
R
E
Y
D
-
Q
DN
V
S
--
W
-
R
--
Q
R
W
S
P
L
Y
-----
D
V
A
L
----------------
Q
E
H
Y
R
K
A
V
A
Y
A
Q
A
S
G
-
L
T
R
-
T
Q
A
D
V
Q
Q
-
M
L
N
P
H
---------------------------------------------------
22
HHSearch
46.04
19%
-4
- C1 -
-
3QSL
1
?
B:
[30-334]
----------------------------------
L
E
K
A
K
V
Q
I
A
V
G
GK
P
-
L
---
I
YY
L
P
---
L
--------
T
I
A
-
E
V
-
K
G
F
F
K
----
D
E
G
L
D
V
S
I
A
D
F
A
---
G
-----
G
S
K
A
L
Q
A
V
V
G
G
S
A
D
V
V
S
G
A
F
E
H
T
L
S
L
Q
A
--
K
G
Q
F
Y
-
R
A
F
A
L
Q
G
-
R
A
P
M
I
G
-
V
G
V
S
K
K
NL
P
G
Y
K
-
G
P
A
D
L
-
K
G
R
K
I
G
V
T
A
P
--------------------------
G
S
S
T
N
M
V
V
N
F
--
F
L
A
K
H
G
L
K
A
S
D
V
S
F
I
G
V
G
A
G
A
G
A
V
--------------------------
T
A
L
R
S
G
Q
I
D
A
I
----------------
S
-
N
T
-
D
P
V
V
S
M
L
----
E
T
S
G
D
I
-----
Q
--
I
I
V
D
T
--
R
T
L
K
D
T
K
E
I
F
G
---
G
--
N
--
M
P
A
--
G
C
L
Y
A
P
Q
A
F
V
D
A
N
P
N
T
A
Q
A
L
T
N
A
I
V
R
A
D
K
W
I
--
Q
K
A
G
A
D
E
I
A
K
A
V
P
E
G
Y
L
L
-
G
--
D
P
A
V
Y
K
A
A
-
I
G
-
K
--
S
M
--
E
-
G
--
L
--
S
-
P
D
-----
G
V
I
P
----------------
E
D
G
A
A
T
A
L
K
A
L
A
A
F
V
P
D
F
D
A
A
K
V
D
P
A
K
-
A
W
T
N
E
---------------------------------------------------
23
HHSearch
45.19
19%
-0
- C1 -
-
3QSL
1
?
A:
[30-334]
----------------------------------
L
E
K
A
K
V
Q
I
A
V
G
GK
P
-
L
---
I
YY
L
P
---
L
--------
T
I
A
-
E
V
-
K
G
F
F
K
----
D
E
G
L
D
V
S
I
A
D
F
A
---
G
-----
G
S
K
A
L
Q
A
V
V
G
G
S
A
D
V
V
S
G
A
F
E
H
T
L
S
L
Q
A
--
K
G
Q
F
Y
-
R
A
F
A
L
Q
G
-
R
A
P
M
I
G
-
V
G
V
S
K
K
NL
P
G
Y
K
-
G
P
A
D
L
-
K
G
R
K
I
G
V
T
A
P
--------------------------
G
S
S
T
N
M
V
V
N
F
--
F
L
A
K
H
G
L
K
A
S
D
V
S
F
I
G
V
G
A
G
A
G
A
V
--------------------------
T
A
L
R
S
G
Q
I
D
A
I
----------------
S
-
N
T
-
D
P
V
V
S
M
L
----
E
T
S
G
D
I
-----
Q
--
I
I
V
D
T
--
R
T
L
K
D
T
K
E
I
F
G
---
G
--
N
--
M
P
A
--
G
C
L
Y
A
P
Q
A
F
V
D
A
N
P
N
T
A
Q
A
L
T
N
A
I
V
R
A
D
K
W
I
--
Q
K
A
G
A
D
E
I
A
K
A
V
P
E
G
Y
L
L
-
G
--
D
P
A
V
Y
K
A
A
-
I
G
-
K
--
S
M
--
E
-
G
--
L
--
S
-
P
D
-----
G
V
I
P
----------------
E
D
G
A
A
T
A
L
K
A
L
A
A
F
V
P
D
F
D
A
A
K
V
D
P
A
K
-
A
W
T
N
E
---------------------------------------------------
32
HHSearch
44.09
14%
-11
- C1 -
-
4ESW
1
THI5_CANAW
B:
[6-296]
----------------------------------
T
N
K
I
T
F
L
L
N
W
E
--
A
-
A
---
P
---
Y
HIP
V
--------
Y
L
A
-
N
I
-
K
G
Y
F
K
----
D
E
N
L
D
I
A
I
L
E
P
S
---
N
-----
P
S
D
V
T
E
L
V
G
S
G
K
V
D
M
G
L
K
A
M
V
G
T
L
A
A
K
A
--
R
G
F
P
V
-
T
S
I
G
S
L
L
-
D
E
P
F
T
G
-
I
C
Y
L
E
G
--
S
G
I
T
S
D
F
Q
S
L
-
K
G
K
R
I
G
Y
V
----------------------------
G
E
F
G
K
I
Q
V
D
E
--
L
T
K
H
Y
G
M
T
P
D
D
Y
V
A
V
R
C
G
--
M
N
V
A
--------------------------
K
Y
I
L
E
G
T
I
D
C
G
----------------
I
-
G
I
-
E
C
I
Q
Q
V
E
LEEA
L
K
E
Q
G
K
DSNDA
K
--
M
L
R
I
D
KL
A
---------
E
L--
G
CC
C
--
F
C
T
--
I
L
Y
I
A
N
D
K
F
I
A
E
N
P
Q
A
V
K
K
F
L
K
A
I
K
R
A
T
D
Y
M
--
L
A
H
-
P
R
E
A
W
A
E
Y
G
N
F
K
P
T
-
M
--
Q
T
D
L
N
T
K
K
-
F
Q
-
R
--
C
Y
--
A
-
Y
--
F
--
S
-
E
S
-----
L
Y
N
V
----------------
H
R
D
W
R
K
V
N
N
Y
G
K
R
L
D
-
I
L
P
-
E
N
Y
-------------------------------------------------------------
48
Fugue
42.96
13%
22
- C1 -
-
2G29
-
NRTA_SYNY3
A:
[28-412]
--
N
A
P
E
V
T
T
A
K
L
G
F
I
A
L
T
D
A
A
P
L
I
I
A
K
E
K
G
F
Y
A
K
Y
G
M
P
D
V
E
V
L
K
Q
--
A
----------------------
S
W
G
-
T
T
-
R
D
N
L
V
L
G
S
A
S
G
G
I
D
G
A
H
I
L
T
P
---
M
-----
P
Y
L
I
T
M
G
T
V
T
D
----
G
K
P
T
P
M
Y
I
L
A
R
L
N
--
V
N
G
Q
G
-
I
Q
L
G
N
N
Y
K
D
L
K
V
G
T
----
D
A
A
--
P
L
K
E
-
A
F
A
K
V
-
T
D
P
K
V
A
M
T
-
F
--------------------------
P
G
G
T
H
D
M
W
I
R
Y
W
L
A
A
G
G
M
E
P
G
K
D
F
S
T
I
V
V
P
-
P
A
Q
M
V
--------------------------
A
N
V
K
V
N
A
M
E
S
F
----------------
C
-
V
G
-
E
P
W
P
L
Q
T
----
V
N
Q
G
V
G
-----
Y
--
Q
A
L
T
T
--
G
---------
Q
---
L
--
W
--
K
D
H
PE
K
A
F
G
M
R
A
D
W
V
D
Q
N
P
K
A
A
K
A
L
L
M
A
V
M
E
A
Q
Q
W
C
D
Q
A
E
N
-
K
E
E
M
C
Q
I
L
S
K
R
E
-
W
-
F
KV
P
F
E
D
I
I
D
R
-
S
K
G
I
--
Y
N
--
F
-
G
--
N
--
G
-
Q
E
-----
T
F
E
D
QEIMQKYWVDNASYPY
K
S
H
D
Q
W
F
L
T
E
N
I
R
W
G
-
Y
L
P
-
A
S
T
D
T
K
A
-
I
V
D
K
V
N
R
E
D
L
W
R
E
A
A
Q
A
L
EVPADQIPSSPSR
G
I
E
T
F
FDG
I
T
F
D
PEN
P
Q
A
Y
L
D
S
LKI
5
PsiBlast_PDB
42.29
26%
47
- C1 -
-
3UIF
1
?
A:
[29-244]
------------------------------------------------------------------------
L
-
V
V
-
N
G
A
F
P
E
E
L
R
K
Q
G
I
K
V
E
W
V
--
P
---
A
AMASV
G
P
V
I
N
E
G
F
A
S
G
K
I
D
F
G
I
Y
G
D
L
P
P
I
I
L
N
A
--
S
K
P
T
V
-
Q
L
V
A
--
P
W
G
T
T
S
N
S
Y
L
V
V
P
K
N
--
S
T
A
K
-
S
I
K
D
L
-
K
G
K
K
I
A
L
H
-
R
--------------------------
G
R
P
W
E
L
A
F
S
N
--
L
L
Q
S
E
G
L
T
F
K
D
F
K
I
V
N
V
N
-
P
Q
V
G
A
--------------------------
A
A
L
A
S
G
T
V
D
G
F
F
S
L
FD
S
Y
I
L
E
D
R
GVGK
I
-
I
W
-
S
T
K
T
A
P
V
----
D
W
K
L
M
G
-----
G
--
V
W
A
R
N
--
D
--------------------------------
F
V
K
Q
N
P
E
I
T
Q
A
I
V
T
A
Y
L
K
S
V
H
W
V
--
A
Q
D
-
E
N
K
E
T
Y
I
R
E
-----------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
42.20
14%
46
- C1 -
-
3UN6
-
?
A:
[51-333]
------------------------------------
Q
Q
V
I
K
I
G
Y
L
--
P
-
I
---
T
---
H
---
S
A
N
L
-----
M
M
T
-
K
K
L
L
S
Q
Y
N
----
H
P
K
Y
K
L
E
L
V
K
F
N
---
N
-----
W
P
D
L
M
D
A
L
N
S
G
R
I
D
G
A
S
T
L
I
E
L
A
M
K
S
K
Q
--
K
G
S
N
I
-
K
A
V
A
L
G
--
H
H
E
G
N
V
-
I
M
G
Q
K
G
--
M
H
L
N
-
E
F
N
N
N
G
D
D
Y
H
F
G
I
P
-
H
R-------------------------
Y
S
T
H
Y
L
L
L
E
E
--
L
R
K
Q
L
K
I
K
P
G
H
F
S
Y
H
E
M
S
-
P
A
E
M
P
--------------------------
A
A
L
S
E
H
R
I
T
G
Y
----------------
S
-
V
A
-
E
P
F
G
A
L
G
----
E
K
L
G
K
G
-----
K
--
T
L
K
H
G
--
D
---------
D
---
V
--
I
PD
A
Y
C
--
C
V
L
V
L
R
G
E
L
L
D
Q
H
K
D
V
A
Q
A
F
V
Q
D
Y
K
K
S
G
-
F
K
--
M
N
D
-
R
K
Q
S
V
D
I
M
T
H
H
F
-
K
-
Q
--
S
R
D
V
L
T
Q
S
-
A
A
-
W
--
T
S
--
Y
-
G
--------
D
-----
L
T
I
K
----------------
P
S
G
Y
Q
E
I
T
T
L
V
K
Q
H
H
-
L
F
N
--
P
P
A
Y
D
D
-
F
V
E
P
S
---------------------------------------------------
28
HHSearch
40.63
15%
50
- C1 -
-
4NMY
1
?
B:
[5-299]
----------------------------------
S
K
K
V
T
M
V
L
D
W
T
--
P
-
N
---
T
NHT
G
---
L
--------
F
V
A
-
L
D
-
K
G
Y
Y
K
----
E
E
G
L
D
V
E
I
V
Q
P
P
---
E
------
S
G
A
E
T
L
V
A
T
G
K
A
D
F
G
I
S
Y
Q
E
Q
V
T
Y
A
K
T
SE
D
P
L
P
I
-
K
A
V
A
T
V
I
-
Q
H
N
T
S
G
-
F
A
S
P
K
E
--
K
N
I
T
-
T
A
K
D
F
-
E
G
K
T
Y
G
G
W
-
G
--------------------------
S
P
S
E
E
A
V
F
K
A
--
V
M
K
K
N
R
A
D
F
N
K
L
K
I
V
N
T
G
-
Q
D
D
F
F
--------------------------
A
A
M
--
K
T
V
D
F
A
----------------
W
-
I
F
-
E
G
W
D
A
V
K
----
A
D
L
I
G
Y
-----
D
LN
F
I
P
V
K
--
D
LDE------
R
---
L
--
D
--
Y
Y
T
--
P
L
I
I
S
N
E
T
V
L
K
D
N
P
E
L
A
K
K
F
L
K
A
T
T
K
G
Y
E
Y
A
--
I
K
N
-
P
E
E
S
A
K
I
L
V
K
H
A
-
P
E
V
--
D
E
K
L
A
L
K
S
-
Q
E
-
Y
--
L
A
SK
Y
-
K
DD
A
--
P
-
R
W
-----
G
E
M
K
----------------
D
S
V
W
N
N
Y
T
S
F
L
K
E
Y
K
-
L
I
D
-
K
D
M
K
A
S
D
-
A
Y
T
N
E
---------------------------------------------------
41
Fugue
40.50
16%
35
- C1 -
-
2DE3
1
SOXB_RHOSG
A:
[20-363]
---------------------------------------
D
T
L
T
Y
S
--
N
-
S
PVP
N
---
A
---
L
--------
L
T
A
-
S
E
-
S
G
F
L
D
A
----
A
G
I
E
L
D
V
L
S
G
Q
---
Q
-----
G
T
V
H
F
T
Y
D
Q
P
A
Y
T
R
F
G
--
G
E
I
P
P
L
L
S
E
G
--
L
R
A
P
G
R
T
R
L
L
G
I
T
P
L
L
G
R
Q
G
-
F
F
V
R
D
D
--
S
P
I
T
-
A
A
A
D
L
-
A
G
R
R
I
G
V
S
-
A
S
A
I
R
I
L
R
GQLGDYLELD
P
W
R
Q
T
L
V
A
L
G
S
W
E
A
R
A
L
L
H
--
T
L
E
H
G
E
L
G
V
D
D
V
E
L
V
P
I
S
-
S
P
G
V
D
VP
A
E
Q
L
E
E
SATVK
G
A
D
L
F
PD
V
A
R
G
Q
A
A
V
L
A
S
G
D
V
D
A
L
----------------
Y
-
S
W
-
L
P
W
A
G
E
L
----
Q
A
T
G
A
R
-----
P
--
V
V
D
L
G
--
L
---------
D
---
E
--
R
N-
A
Y
A
--
S
V
W
T
V
S
S
G
L
V
R
Q
R
P
G
L
V
Q
R
L
V
D
A
A
V
D
A
G
L
W
A
--
R
D
H
-
S
D
A
V
T
S
L
H
A
A
N
L
-
G
-
V
--
S
T
G
A
V
G
Q
G
-
F
G
-
A
DF
Q
Q
--
R
-
L
--
V
--
P
-
R
L
-----
D
H
D
A
----------------
L
A
L
L
E
R
T
Q
Q
F
L
L
T
N
N
-
L
L
Q
-
E
P
V
A
L
D
Q
-
W
A
A
P
E
F
L
N
N
S
L
N
R-------------------------------------------
16
PsiBlast_PDB
40.22
42%
-187
- C1 -
-
2O1M
-
TCYK_BACSU
A:
[110-147]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
Q
N
N
--
D
T
I
R
-
G
I
E
D
L
-
K
G
K
R
V
I
T
S
-
A
--------------------------
T
S
N
G
A
L
V
L
K
K
--
W
N
E
D
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------