@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMN6: (2017-11-09 )
MKYSEYQPRPDLLKDRIILITGAGDGIGRAAALSYALHGATVVLHGRTLNKLEVIYDEIEGLGAPQPAILPLQLSSASDRDYDFLVSTLEKQFGRLDGILHNAGILGERVELAHYPAEVWDDVMAVNLRAPFALTQALLPLLQKSENASVVFTSSGVGREARALWGAYSVSKVAIEAVSKIFAAEHTYPNIRFNCINPGATRTAMRAKAYPEEDPKTLPTPESIMPAYLYLMGEDSLTLNGQSIDAQD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160-.......170.......180...-...-.--190.......200.------------......210------------------.--------...----------..------------.-------------.220-.......230...--.-------...240......------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKYSEYQP
R
P
D
L
LKD
R
I
I
L
I
TGAGDGI
G
R
A
A
A
L
S
Y
ALH
G
A
T
V
V
L
HGRTL
N
K
L
E
V
I
Y
D
E
I
E
GLGAPQP
A
I
L
P
L
QLSSASDR
D
Y
D
F
L
V
S
T
L
E
K
Q
F
G
R
L
D
G
I
L
HNAGILGE
R
V
E
LAHY
P
A
E
V
W
D
D
V
M
A
V
NLRA
P
F
A
L
T
Q
A
L
L
P
L
L
QKSEN
A
S
V
V
F
TSSGVG
R
E
A
R
-
A
L
W
GA
Y
S
V
S
K
V
A
I
E
A
V
S
K
I
F
A
AE-HTY-P--N
I
R
F
N
C
INPGA
T
R
T
------------
A
M
RAKAYP-------------------E--------EDP----------KT------------L-------------PT
P
E
-
S
I
M
P
A
Y
L
Y
L
MGED--
S
-------
L
T
LNGQSIDAQD------------------------------
4
PsiBlast_PDB
95.08
51%
-106
- C1 -
-
3G1T
-
?
A:
[5-246]
-----
Y
Q
P
K
Q
D
L
L
Q
N
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
L
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
R
V
A
Q
H
I
A
D
E
Q
H
V
Q
P
Q
W
F
T
L
D
L
L
T
C
T
A
E
E
C
R
Q
V
A
D
R
I
A
A
H
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
E
I
G
P
M
S
E
Q
D
P
Q
I
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
T
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
N
-
R
--
S
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
S
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
9
PsiBlast_PDB
94.52
49%
-106
- C1 -
-
3IAH
3
?
A:
[6-247]
-----
Y
Q
P
K
Q
D
L
L
Q
N
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
L
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
R
V
A
Q
H
I
A
D
E
Q
H
V
Q
P
Q
W
F
T
L
D
L
L
T
C
T
A
E
E
C
R
Q
V
A
D
R
I
A
A
H
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
E
I
G
P
M
S
E
Q
D
P
Q
I
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
T
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
N
-
R
--
S
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
S
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
10
PsiBlast_PDB
94.51
50%
-108
- C1 -
-
3E9Q
2
YCIK_ECOLI
A:
[24-264]
-----
Y
Q
P
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
N
C
Q
Q
L
A
Q
R
I
V
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
N
P
Q
V
W
Q
D
V
M
Q
I
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
A
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
2
PsiBlast_PDB
93.91
52%
-105
- C1 -
-
3GZ4
1
?
A:
[6-245]
------
Q
P
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
D
C
Q
Q
L
A
Q
R
I
A
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
D
P
Q
V
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
A
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
7
PsiBlast_PDB
93.76
50%
-110
- C1 -
-
3F1K
1
YCIK_ECOLI
A:
[3-243]
-----
Y
Q
P
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
N
C
Q
Q
L
A
Q
R
I
A
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
N
P
Q
V
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
A
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
21
PsiBlast_CBE
93.35
52%
-106
- C1 -
-
3GZ4
1
?
B:
[7-245]
-------
P
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
D
C
Q
Q
L
A
Q
R
I
A
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
D
P
Q
V
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
A
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
6
PsiBlast_PDB
92.46
51%
-112
- C1 -
-
3GY0
1
?
A:
[4-241]
--------
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
N
C
Q
Q
L
A
Q
R
I
V
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
N
P
Q
V
W
Q
D
V
M
Q
I
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
------------
A
M
R
A
S
A
F
P
-------------------
T
--------
E
D
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
57
HHSearch
91.15
55%
-79
- C1 -
-
3I1J
7
?
A:
[7-247]
-------
A
H
P
E
L
L
K
G
R
V
I
L
V
T
G
A
A
R
G
I
G
A
A
A
A
R
A
Y
A
A
H
G
A
S
V
V
L
L
G
R
T
E
A
S
L
A
E
V
S
D
Q
I
K
S
A
G
Q
P
Q
P
L
I
I
A
L
N
L
E
N
A
T
A
Q
Q
Y
R
E
L
A
A
R
V
E
H
E
F
G
R
L
D
G
L
L
H
N
A
S
I
I
G
P
R
T
P
L
E
Q
L
P
D
E
D
F
M
Q
V
M
H
V
N
V
N
A
T
F
M
L
T
R
A
L
L
P
L
L
K
R
S
E
D
A
S
I
A
F
T
S
S
S
V
G
R
K
G
R
-
A
N
W
G
A
Y
G
V
S
K
F
A
T
E
G
L
M
Q
T
L
A
D
E
-
L
E
G
V
T
--
A
V
R
A
N
S
I
N
P
G
A
T
R
T
------------
G
M
R
A
Q
A
Y
P
-------------------
D
--------
E
N
P
----------
L
N
------------
N
-------------
P
A
P
E
-
D
I
M
P
V
Y
L
Y
L
M
G
P
D
--
S
-------
T
G
I
N
G
Q
A
L
N
A
Q
-------------------------------
8
PsiBlast_PDB
90.97
52%
-78
- C1 -
-
3I1J
7
?
A:
[4-247]
----
D
Y
S
A
H
P
E
L
L
K
G
R
V
I
L
V
T
G
A
A
R
G
I
G
A
A
A
A
R
A
Y
A
A
H
G
A
S
V
V
L
L
G
R
T
E
A
S
L
A
E
V
S
D
Q
I
K
S
A
G
Q
P
Q
P
L
I
I
A
L
N
L
E
N
A
T
A
Q
Q
Y
R
E
L
A
A
R
V
E
H
E
F
G
R
L
D
G
L
L
H
N
A
S
I
I
G
P
R
T
P
L
E
Q
L
P
D
E
D
F
M
Q
V
M
H
V
N
V
N
A
T
F
M
L
T
R
A
L
L
P
L
L
K
R
S
E
D
A
S
I
A
F
T
S
S
S
V
G
R
K
G
R
-
A
N
W
G
A
Y
G
V
S
K
F
A
T
E
G
L
M
Q
T
L
A
D
E
L
E
G
V
-
T
--
A
V
R
A
N
S
I
N
P
G
A
T
R
T
------------
G
M
R
A
Q
A
Y
P
-------------------
D
--------
E
N
P
----------
L
N
------------
N
-------------
P
A
P
E
-
D
I
M
P
V
Y
L
Y
L
M
G
P
D
--
S
-------
T
G
I
N
G
Q
A
L
N
A
Q
-------------------------------
5
PsiBlast_PDB
89.98
51%
-116
- C- -
-
3F5S
-
?
A:
[5-241]
---------
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
N
C
Q
Q
L
A
Q
R
I
V
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
N
P
Q
V
W
Q
D
V
M
Q
I
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
T
--------------------------------------------------
P
----------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
1
PsiBlast_PDB
89.19
52%
-109
- C- -
-
3F5Q
-
?
A:
[6-245]
------
Q
P
K
Q
D
L
L
N
D
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
K
L
R
Q
V
A
S
H
I
N
E
E
T
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
D
C
Q
Q
L
A
Q
R
I
A
V
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
G
D
V
C
P
M
S
E
Q
D
P
Q
V
W
Q
D
V
M
Q
V
N
V
N
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
A
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
-
A
N
W
G
A
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
-
Y
Q
Q
----
R
L
R
V
N
C
I
N
P
G
G
T
R
--------------------------------------------------------------
Q
K
------------
L
-------------
K
T
P
A
-
D
I
M
P
L
Y
L
W
L
M
G
D
D
--
S
-------
R
R
K
T
G
M
T
F
D
A
Q
-------------------------------
58
HHSearch
86.23
55%
-81
- C1 -
-
3I1J
4
?
B:
[7-247]
-------
A
H
P
E
L
L
K
G
R
V
I
L
V
T
G
A
A
R
G
I
G
A
A
A
A
R
A
Y
A
A
H
G
A
S
V
V
L
L
G
R
T
E
A
S
L
A
E
V
S
D
Q
I
K
S
A
G
Q
P
Q
P
L
I
I
A
L
N
L
E
N
A
T
A
Q
Q
Y
R
E
L
A
A
R
V
E
H
E
F
G
R
L
D
G
L
L
H
N
A
S
I
I
G
P
R
T
P
L
E
Q
L
P
D
E
D
F
M
Q
V
M
H
V
N
V
N
A
T
F
M
L
T
R
A
L
L
P
L
L
K
R
S
E
D
A
S
I
A
F
T
S
S
S
V
G
R
K
G
R
-
A
N
W
G
A
Y
G
V
S
K
F
A
T
E
G
L
M
Q
T
L
A
D
E
-
L
E
G
V
T
--
A
V
R
A
N
S
I
N
P
G
A
T
R
T
------------
G
M
R
A
-
A
Y
------------------------------
N
P
----------
L
N
------------
N
-------------
P
A
P
E
-
D
I
M
P
V
Y
L
Y
L
M
G
P
D
--
S
-------
T
G
I
N
G
Q
A
L
N
A
Q
-------------------------------
11
PsiBlast_PDB
80.83
37%
-113
- C1 -
-
4Z0T
2
?
A:
[13-243]
------------
L
T
G
R
L
A
L
V
T
G
A
S
R
G
I
G
Y
F
L
S
L
E
L
A
K
R
G
A
H
V
I
A
V
A
R
T
V
G
G
L
E
E
L
D
D
E
I
R
K
L
G
S
-
S
A
T
L
V
P
L
D
I
T
D
M
E
A
--
L
D
R
L
G
G
T
I
H
E
R
W
G
K
L
D
I
L
V
A
N
A
G
I
L
G
T
I
S
P
I
G
H
V
E
A
K
T
F
E
K
V
M
N
I
N
V
T
S
V
W
R
L
I
R
S
V
D
P
L
L
R
A
S
D
A
G
R
A
I
M
L
S
S
G
V
A
H
S
C
R
-
A
F
W
G
P
Y
A
A
S
K
A
A
V
E
V
M
A
R
C
W
A
E
E
-
T
K
K
-
M
--
K
L
K
I
N
S
V
N
P
G
A
T
R
T
------------
A
M
R
A
Q
A
M
P
-------------------
G
--------
E
D
P
----------
E
T
------------
L
-------------
P
T
P
Q
-
S
V
A
E
K
I
V
K
L
-
A
D
P
--
K
-------
L
E
V
T
G
K
L
F
D
V
R
-------------------------------
13
PsiBlast_PDB
74.74
27%
-92
- C1 -
-
3O4R
3
DHRS4_HUMAN
A:
[8-251]
-------
T
R
R
D
P
L
A
N
K
V
A
L
V
T
A
S
T
D
G
I
G
F
A
I
A
R
R
L
A
Q
D
G
A
H
V
V
V
S
S
R
K
Q
Q
N
V
D
Q
A
V
A
T
L
Q
G
E
G
L
S
V
T
G
T
V
-
C
H
V
G
K
A
E
D
R
E
R
--
L
V
A
T
A
V
K
L
H
G
G
I
D
I
L
V
S
N
A
A
V
N
P
F
F
G
S
I
M
D
V
T
E
E
V
W
D
K
T
L
D
I
N
V
K
A
P
A
L
M
T
K
A
V
V
P
E
M
E
K
R
G
G
G
S
V
V
I
V
S
S
I
A
A
F
S
P
S
-
P
G
F
S
P
Y
N
V
S
K
T
A
L
L
G
L
T
K
T
L
A
I
E
-
L
A
P
-
R
--
N
I
R
V
N
C
L
A
P
G
L
I
K
T
------------
S
F
S
R
M
L
W
M
-------------------
D
--------
K
E
K
E
E
S
M
K
E
T
L
RI
R
R
------------
L
-------------
G
E
P
E
-
D
C
A
G
I
V
S
F
L
C
S
E
D
--
A
-------
S
Y
I
T
G
E
T
V
----------------------------------
56
HHSearch
74.53
27%
-119
- C1 -
-
3UCX
2
?
A:
[7-257]
----------
G
L
L
T
D
K
V
V
V
I
S
G
V
G
P
A
L
G
T
T
L
A
R
R
C
A
E
Q
G
A
D
L
V
L
A
A
R
T
V
E
R
L
E
D
V
A
K
Q
V
T
D
T
-
G
R
R
A
L
S
V
G
T
D
I
T
D
D
--
A
Q
V
A
H
L
V
D
E
T
M
K
A
Y
G
R
V
D
V
V
I
N
N
A
F
R
V
P
S
M
K
P
F
A
N
T
T
F
E
H
M
R
D
A
I
E
L
T
V
F
G
A
L
R
L
I
Q
G
F
T
P
A
L
E
E
S
-
K
G
A
V
V
N
V
N
S
M
V
V
R
H
S
Q
-
A
K
Y
G
A
Y
K
M
A
K
S
A
L
L
A
M
S
Q
T
L
A
T
E
-
L
G
E
-
K
--
G
I
R
V
N
S
V
L
P
G
Y
I
W
G
------------
G
T
L
K
S
Y
F
E
H
Q
A
G
K
Y
GTS
V
E
D
I
Y
N
A
A
A
A
G
--------
S
D
L
----------
K
R
------------
L
-------------
P
T
E
D
-
E
V
A
S
A
I
L
F
M
A
S
D
L
--
A
-------
S
G
I
T
G
Q
A
L
D
V
--------------------------------
15
PsiBlast_PDB
71.07
27%
-95
- C1 -
-
4DQX
-
?
A:
[25-269]
------------
L
N
Q
R
V
C
I
V
T
G
G
G
S
G
I
G
R
A
T
A
E
L
F
A
K
N
G
A
Y
V
V
V
A
D
V
N
E
D
A
A
V
R
V
A
N
E
I
------
G
S
K
A
F
G
V
R
V
D
V
S
S
A
K
D
A
E
S
M
V
E
K
T
T
A
K
W
G
R
V
D
V
L
V
N
N
A
G
-
F
G
T
T
G
N
V
V
T
I
P
E
E
T
W
D
R
I
M
S
V
N
V
K
G
I
F
L
C
S
K
Y
V
I
P
V
M
R
R
N
G
G
G
S
I
I
N
T
T
S
Y
T
A
T
S
A
I
-
A
D
R
T
A
Y
V
A
S
K
G
A
I
S
S
L
T
R
A
M
A
M
D
-
H
A
K
-
E
--
G
I
R
V
N
A
V
A
P
G
T
I
D
S
------------
P
Y
F
T
K
I
F
A
-------------------
E
A-------
K
D
P
----------
A
K
------------
L
R
S
D
F
N
A
RAVMD
R
M
G
T
A
E
-
E
I
A
E
A
M
L
F
L
A
S
D
R
--
S
RFATG
S
I
L
T
V
D
G
G
S
-----------------------------------
12
PsiBlast_PDB
69.47
26%
-95
- C1 -
-
4FN4
3
?
A:
[5-245]
------------
L
K
N
K
V
V
I
V
T
G
A
G
S
G
I
G
R
A
I
A
K
K
F
A
L
N
D
S
I
V
V
A
V
E
L
L
E
D
R
L
N
Q
I
V
Q
E
L
R
G
M
G
K
E
---
V
L
G
V
K
A
D
V
S
K
K
K
D
V
E
E
F
V
R
R
T
F
E
T
Y
S
R
I
D
V
L
C
N
N
A
G
I
M
D
G
V
T
P
V
A
E
V
S
D
E
L
W
E
R
V
L
A
V
N
L
Y
S
A
F
Y
S
S
R
A
V
I
P
I
M
L
K
Q
G
K
G
V
I
V
N
T
A
S
I
A
G
I
R
G
G
-
F
A
G
A
P
Y
T
V
A
K
H
G
L
I
G
L
T
R
S
I
A
A
H
-
Y
G
D
-
Q
--
G
I
R
A
V
A
V
L
P
G
T
V
K
T
NIGLGSSKPS
E
L
G
M
R
T
L
T
K
L
-------------------
M
--------
S
L
S
----------
S
R
------------
L
-------------
A
E
P
E
-
D
I
A
N
V
I
V
F
L
A
S
D
E
--
A
-------
S
F
V
N
G
D
A
V
----------------------------------
16
PsiBlast_PDB
67.55
30%
-78
- C1 -
-
3TOX
1
?
A:
[6-247]
------------
L
E
G
K
I
A
I
V
T
G
A
S
S
G
I
G
R
A
A
A
L
L
F
A
R
E
G
A
K
V
V
V
T
A
R
N
G
N
A
L
A
E
L
T
D
E
I
A
---
G
G
G
G
E
A
A
A
L
A
G
D
V
G
D
E
A
L
H
E
A
L
V
E
L
A
V
R
R
F
G
G
L
D
T
A
F
N
N
A
G
A
L
G
A
M
G
E
I
S
S
L
S
V
E
G
W
R
E
T
L
D
T
N
L
T
S
A
F
L
A
A
K
Y
Q
V
P
A
I
A
A
L
G
G
G
S
L
T
F
T
S
S
F
V
G
H
T
A
G
F
A
G
V
A
P
Y
A
A
S
K
A
G
L
I
G
L
V
Q
A
L
A
V
E
-
L
G
A
-
R
--
G
I
R
V
N
A
L
L
P
G
G
T
D
T
------------
P
A
N
F
A
N
L
P
-------------------
G
--------
A
A
P
----------
E
T
R
G
F
V
E
G
L
HALK
R
I
-------------
A
R
P
E
-
E
I
A
E
A
A
L
Y
L
A
S
D
G
--
A
-------
S
F
V
T
G
A
A
L
----------------------------------
48
HHSearch
63.04
25%
-97
* C1 *
-
5JY1
3
?
A:
[9-254]
---------
M
G
L
L
E
Q
R
V
A
L
V
T
G
A
G
G
G
I
G
R
G
V
A
R
S
F
G
N
E
G
A
A
V
I
I
A
E
I
N
E
S
T
G
R
Q
V
E
Q
E
I
R
E
M
-
G
G
R
S
L
F
V
K
T
D
V
T
S
K
--
A
S
I
E
A
A
V
R
S
A
V
E
Q
F
G
S
L
D
I
L
V
N
N
A
F
V
P
T
P
N
V
L
L
E
E
K
T
D
E
M
L
E
Q
T
L
T
T
S
L
W
A
T
W
W
A
M
R
A
A
F
V
P
M
R
E
R
R
W
G
R
I
V
N
F
Y
S
I
D
T
E
T
G
A
-
W
L
H
G
D
Y
N
T
A
K
A
G
I
V
G
L
T
R
S
A
A
S
E
-
W
G
R
-
F
--
N
I
T
V
N
A
I
A
P
T
A
M
G
A
------------
T
F
F
E
L
A
A
K
N
P
-----------------
E
F
A
E
R
S
A
A
A
R
P
L
----------
G
R
------------
S
-------------
G
D
P
E
Q
D
I
G
P
A
A
V
F
F
A
S
E
M
--
S
-------
R
F
V
T
G
E
T
L
H
V
D
-------------------------------
64
Fugue
62.69
22%
-96
- C1 -
-
1XSE
1
DHI1_CAVPO
A:
[22-295]
----
N
E
K
F
R
P
E
M
L
Q
G
K
K
V
I
V
T
G
A
S
K
G
I
G
R
E
I
A
Y
H
L
A
K
M
G
A
H
V
V
V
T
A
R
S
K
E
A
L
Q
K
V
V
A
R
C
L
E
L
G
A
A
S
A
H
Y
I
A
G
S
M
E
D
--
M
T
F
A
E
E
F
V
A
E
A
G
N
L
M
G
G
L
D
M
L
I
L
N
H
V
L
Y
N
R
L
-
T
F
F
H
G
E
I
D
N
V
R
K
S
M
E
V
N
F
H
S
F
V
V
L
S
V
A
A
M
P
M
L
M
Q
S
-
Q
G
S
I
A
V
V
S
S
V
A
G
K
I
T
Y
-
P
L
I
A
P
Y
S
A
S
K
F
A
L
D
G
F
F
S
T
L
R
S
E
-
F
L
V
-
N
KV
N
V
S
I
T
L
C
I
L
G
L
I
D
T
------------
E
T
A
I
K
A
T
S
-------------------
G
--------
I
Y
L
----------
G
P
------------
A
-------------
S
P
K
E
-
E
C
A
L
E
I
I
K
G
T
A
L
R
QD
E
-------
M
Y
Y
V
G
S
R
W
V
P
Y
L
L
G
N
P
G
R
K
I
M
E
F
L
S
A
A
E
YN
W
D
N
V
L
S
N
E
K
L
YG