@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMV7: (2017-11-11 )
MDENKSKALQAALSQIEKQFGKNTVMRLGDNTVQAVEAVSTGSLTLDIALGIGGLPKGRIIEIYGPESSGKTTMTLQAIAQCQKSGGTCAFIDAEHALDPQYARKLGVDIDNLLVSQPDNGEQALEIADMLVRSGAIDLIVVDSVAALTPKAEIEGEMGDSHMGLQARLMSQALRKITGNAKRSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGQVKEGDEIVGSETKVKVVKNKMAPPFKEAIFQILYGKGTNQLGELVDLAVQQDIVQKAGAWYSYQGNKIGQGKNNVIRYFEENTQIAEEIERNIREQLLTTGTNGAVQIEDEEEPDLLLES
Atome Classification :
(39 SA)
.........10........20........30.-.......40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MDE
N
K
S
K
A
L
Q
A
A
L
S
Q
I
E
K
Q
FGK
N
T
V
M
RLGDNT-
V
Q
A
V
E
AVSTG
S
L
T
L
D
I
A
LGIGGLPKG
R
I
I
E
I
YGPESSG
K
T
T
M
T
L
Q
A
I
A
Q
C
Q
KSGG
T
C
A
F
IDAEHAL
D
P
Q
Y
A
R
K
LGV
D
I
D
N
L
LVSQPDN
G
E
Q
A
L
E
I
A
D
M
L
V
RSG
A
I
D
L
I
V
VDSVAALTPK
A
E
I
EGEMGDSH
M
G
L
Q
A
R
L
M
S
Q
A
L
R
K
I
TGNAKRS
N
C
M
V
I
F
I
N
Q
I
R
M
K
I
G
V
M
FGSPETTTGG
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
IGQVKEGDEIVGSE
T
K
V
K
V
V
K
NKMAP
P
F
K
E
A
I
F
Q
I
L
YGKGT
N
Q
L
G
E
L
V
D
L
A
V
Q
Q
D
I
V
Q
KAGA
W
Y
SYQGNKIGQGK
N
N
V
I
R
Y
F
EEN
T
Q
I
A
E
E
I
E
R
N
I
R
E
Q
L
L
TTGTN
G
A
V
Q
I
EDEEEPDLLLES
44
HHSearch
88.63
74%
-100
- C2 -
-
3CMW
3
RECA_ECOLI
A:
[331-719]
-----
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
S
N
P
-------------------
51
HHSearch
87.96
74%
-102
- C2 -
-
3CMW
3
RECA_ECOLI
A:
[331-715]
-----
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
-----------------------
46
HHSearch
87.50
74%
-97
- C2 -
-
3CMT
4
RECA_ECOLI
D:
[331-719]
-----
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
S
N
P
-------------------
3
PsiBlast_PDB
87.43
74%
-90
- C2 -
-
4TWZ
-
RECA_ECOLI
A:
[6-329]
----
K
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
-
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
-
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
S
---------------------
53
HHSearch
86.58
74%
-99
- C2 -
-
3CMT
4
RECA_ECOLI
D:
[332-715]
------
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
-----------------------
52
HHSearch
86.06
74%
-93
- C2 -
-
3CMU
3
RECA_ECOLI
A:
[334-729]
--------
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
S
N
--------------------
45
HHSearch
86.06
74%
-92
- C2 -
-
3CMU
3
RECA_ECOLI
A:
[334-730]
--------
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
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C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
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K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
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G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
S
N
P
-------------------
4
PsiBlast_PDB
85.27
72%
-104
- C2 -
-
5JRJ
1
?
A:
[12-334]
----
K
S
K
A
L
A
A
A
L
A
Q
I
E
K
Q
F
G
K
G
S
V
M
R
M
E
D
G
V
-
I
--
I
Q
A
V
S
T
G
S
L
G
L
D
I
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
S
I
A
E
M
Q
K
L
G
G
T
C
A
F
I
D
A
E
H
A
L
D
V
T
Y
A
Q
K
L
G
V
N
L
N
D
L
L
I
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
V
R
S
G
A
V
D
L
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
------------
R
L
M
S
Q
A
L
R
K
L
T
G
S
I
N
R
T
N
T
T
V
I
F
I
N
Q
I
----------------
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
T
G
S
I
K
S
G
D
E
V
I
G
S
E
T
K
V
K
V
V
K
N
K
V
A
P
P
F
R
E
A
H
F
D
I
L
Y
G
E
G
T
S
R
E
G
E
I
L
D
L
G
S
E
H
K
V
V
E
K
S
G
A
W
Y
S
Y
N
G
E
R
I
G
Q
G
K
D
N
A
R
N
Y
L
K
E
H
P
E
L
A
R
E
I
E
N
K
V
R
V
A
L
-----------------------
1
PsiBlast_PDB
84.42
74%
-103
- C2 -
-
1XMS
1
RECA_ECOLI
A:
[7-332]
-
D
E
N
K
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
----------
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
----------------
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
L
----------------------
18
PsiBlast_PDB
83.52
65%
-88
- C2 -
-
2ZRO
2
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
E
K
I
G
------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
54
HHSearch
83.16
74%
-93
- C2 -
-
3CMV
-
RECA_ECOLI
A:
[332-759]
------
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
E
I
G
D
S
H
M
G
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
R
M
K
I
G
V
M
F
G
N
P
E
T
T
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
-----------------------
21
PsiBlast_CBE
82.99
65%
-95
- C2 -
-
2ZRA
4
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
--
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
E
L
R
-------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
32
PsiBlast_CBE
82.76
64%
-86
- C2 -
-
4PQY
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
------------
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
29
PsiBlast_CBE
82.65
65%
-90
- C2 -
-
2ZRJ
4
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
---
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
A
L
R
----------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
31
PsiBlast_CBE
82.22
64%
-84
- C2 -
-
4PR0
4
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
-------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
23
PsiBlast_CBE
82.10
65%
-93
- C2 -
-
2ZRF
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
N
L
R
----------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
----
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
26
PsiBlast_CBE
82.01
65%
-82
- C2 -
-
2ZRC
2
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
N
L
R
--------
S
P
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
19
PsiBlast_PDB
82.00
65%
-92
- C2 -
-
2ZRP
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
-----
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
-------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
17
PsiBlast_PDB
81.93
65%
-86
- C2 -
-
2ZRM
3
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
----------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
24
PsiBlast_CBE
81.57
65%
-89
- C2 -
-
2ZRE
2
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
N
L
R
----------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
28
PsiBlast_CBE
81.56
65%
-86
- C2 -
-
2ZRK
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
A
L
R
----------
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
34
PsiBlast_CBE
81.46
64%
-85
- C2 -
-
1MO5
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
------------
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
L
A
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
25
PsiBlast_CBE
81.37
65%
-86
- C2 -
-
2ZRD
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
N
L
R
E
--------
P
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
22
PsiBlast_CBE
80.89
65%
-95
- C2 -
-
2ZRG
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
-----
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
N
L
R
E
------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
10
PsiBlast_PDB
80.56
65%
-83
- C2 -
-
2ODN
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
--
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
--------------
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
33
PsiBlast_CBE
80.07
64%
-95
- C2 -
-
1MO6
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
-------
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
-------------
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
L
A
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
35
PsiBlast_CBE
79.81
64%
-84
- C2 -
-
1MO4
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
-----
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
D
K
I
G
V
M
F
G
S
P
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
L
A
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
13
PsiBlast_PDB
79.72
65%
-84
- C2 -
-
2OEP
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
-
E
K
I
G
V
M
F
G
S
P
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
7
PsiBlast_PDB
79.70
65%
-83
- C2 -
-
1UBF
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
-------
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
E
K
I
----------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
36
PsiBlast_CBE
79.69
64%
-86
- C2 -
-
1MO3
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
E
M
---
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
-------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
L
A
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
9
PsiBlast_PDB
79.60
65%
-95
- C2 -
-
2G88
3
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
------
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
------------
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
37
PsiBlast_CBE
79.29
64%
-87
- C2 -
-
1G18
1
RECA_MYCTU
A:
[6-328]
---
D
R
E
K
A
L
E
L
A
V
A
Q
I
E
K
S
Y
G
K
G
S
V
M
R
L
G
D
E
A
-
R
Q
P
I
S
V
I
P
T
G
S
I
A
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
V
A
A
F
I
D
A
E
H
A
L
D
P
D
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
I
R
S
G
A
L
D
I
V
V
I
D
S
V
A
A
L
V
P
R
A
E
L
E
G
E
M
---
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
--------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
M
D
V
R
R
V
E
T
L
K
D
G
T
N
A
V
G
N
R
T
R
V
K
V
V
K
N
K
C
L
A
P
F
K
Q
A
E
F
D
I
L
Y
G
K
G
I
S
R
E
G
S
L
I
D
M
G
V
D
Q
G
L
I
R
K
S
G
A
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
N
F
L
V
E
N
A
D
V
A
D
E
I
E
K
K
I
K
E
K
L
-----------------------
39
HHSearch
79.26
64%
-90
- C2 -
-
2G88
3
RECA_MYCS2
A:
[6-335]
--
P
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
------
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
------------
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
G
I
G
A
V
V
-----------------
11
PsiBlast_PDB
79.11
65%
-86
- C2 -
-
2ODW
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
------
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
E
------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
8
PsiBlast_PDB
79.11
65%
-76
- C2 -
-
1UBG
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
M
G
D
S
H
V
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
L
R
E
K
I
G
V
M
F
G
S
P
E
T
T
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
27
PsiBlast_CBE
78.74
65%
-84
- C2 -
-
2ZRL
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
E
------
G
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
A
L
--------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
2
PsiBlast_PDB
78.26
74%
-
- C2 -
-
1REA
1
RECA_ECOLI
A:
[3-327]
-
D
E
N
K
Q
K
A
L
A
A
A
L
G
Q
I
E
K
Q
F
G
K
G
S
I
M
R
L
G
E
D
R
-
S
M
D
V
E
T
I
S
T
G
S
L
S
L
D
I
A
L
G
A
G
G
L
P
M
G
R
I
V
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
V
I
A
A
A
Q
R
E
G
K
T
C
A
F
I
D
A
E
H
A
L
D
P
I
Y
A
R
K
L
G
V
D
I
D
N
L
L
C
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
A
R
S
G
A
V
D
V
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
G
--------
L
A
A
R
M
M
S
Q
A
M
R
K
L
A
G
N
L
K
Q
S
N
T
L
L
I
F
I
N
Q
I
--------------
T
G
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
I
G
A
V
K
E
G
E
N
V
V
G
S
E
T
R
V
K
V
V
K
N
K
I
A
A
P
F
K
Q
A
E
F
Q
I
L
Y
G
E
G
I
N
F
Y
G
E
L
V
D
L
G
V
K
E
K
L
I
E
K
A
G
A
W
Y
S
Y
K
G
E
K
I
G
Q
G
K
A
N
A
T
A
W
L
K
D
N
P
E
T
A
K
E
I
E
K
K
V
R
E
L
L
-----------------------
6
PsiBlast_PDB
77.86
65%
-84
- C2 -
-
1UBE
1
RECA_MYCS2
A:
[7-329]
---
D
R
E
K
A
L
E
L
A
M
A
Q
I
D
K
N
F
G
K
G
S
V
M
R
L
G
E
E
V
-
R
Q
P
I
S
V
I
P
T
G
S
I
S
L
D
V
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
V
A
L
H
A
V
A
N
A
Q
A
A
G
G
I
A
A
F
I
D
A
E
H
A
L
D
P
E
Y
A
K
K
L
G
V
D
T
D
S
L
L
V
S
Q
P
D
T
G
E
Q
A
L
E
I
A
D
M
L
V
R
S
G
A
L
D
I
I
V
I
D
S
V
A
A
L
V
P
R
A
E
I
E
G
--------
L
Q
A
R
L
M
S
Q
A
L
R
K
M
T
G
A
L
N
N
S
G
T
T
A
I
F
I
N
Q
---------------
T
G
G
K
A
L
K
F
Y
A
S
V
R
L
D
V
R
R
I
E
T
L
K
D
G
T
D
A
V
G
N
R
T
R
V
K
V
V
K
N
K
V
S
P
P
F
K
Q
A
E
F
D
I
L
Y
G
Q
G
I
S
R
E
G
S
L
I
D
M
G
V
E
H
G
F
I
R
K
S
G
S
W
F
T
Y
E
G
E
Q
L
G
Q
G
K
E
N
A
R
K
F
L
L
E
N
T
D
V
A
N
E
I
E
K
K
I
K
E
K
L
-----------------------
41
HHSearch
67.57
71%
35
- C2 -
-
5JRJ
1
?
A:
[10-339]
--
S
E
K
S
K
A
L
A
A
A
L
A
Q
I
E
K
Q
F
G
K
G
S
V
M
R
M
E
D
G
V
I---
I
Q
A
V
S
T
G
S
L
G
L
D
I
A
L
G
I
G
G
L
P
R
G
R
V
I
E
I
Y
G
P
E
S
S
G
K
T
T
L
T
L
Q
S
I
A
E
M
Q
K
L
G
G
T
C
A
F
I
D
A
E
H
A
L
D
V
T
Y
A
Q
K
L
G
V
N
L
N
D
L
L
I
S
Q
P
D
T
G
E
Q
A
L
E
I
C
D
A
L
V
R
S
G
A
V
D
L
I
V
V
D
S
V
A
A
L
T
P
K
A
E
I
E
------------
R
L
M
S
Q
A
L
R
K
L
T
G
S
I
N
R
T
N
T
T
V
I
F
I
N
Q
I
----------------
G
N
A
L
K
F
Y
A
S
V
R
L
D
I
R
R
T
G
S
I
K
S
G
D
E
V
I
G
S
E
T
K
V
K
V
V
K
N
K
V
A
P
P
F
R
E
A
H
F
D
I
L
Y
G
E
G
T
S
R
E
G
E
I
L
D
L
G
S
E
H
K
V
V
E
K
S
G
A
W
Y
S
Y
N
G
E
R
I
G
Q
G
K
D
N
A
R
N
Y
L
K
E
H
P
E
L
A
R
E
I
E
N
K
V
R
V
A
L
G
V
P
E
L
------------------