@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VN95: (2017-11-13 )
MVQFTKQAKINQEHLQTWQDRGLIIPDLVRADRYLSFIGYYRLSAYTIPFQQIVTTPSTVLHQFKANTTFDDVLNLYIFDRELRLLIMDAIERIEVAIRAQICNVLCHLSGNAFWYTDEQHFNHHYAHMRLLASIERQLLDEKERLIRDEKAIDKRPLSQADKDVLKDKVRKENFLRHYLSKYDSPKLPPSWMMIEMLTWGELSHLYVGLKSNQAKKQIAQNLGLHAEVLESWLKSLNDVRNLCAHHSRLWNKEHGRSIKIPTSNAIQWLQQPIILSNTAIRYEKRTYMLLVAIQTLLYKISPNSTWAKRLKDLIEQYPSLSKANMGMPELWHQDPFWQQALQQN
Atome Classification :
(20 SA)
.........10........-20..--......30......--.--.40.---------.....---..50.....--...60......--..70........80.......-.90..-----......100.......110--..-...----..120------...---.....130-----...---......140--.........150....----------...160.......170.....----..180....-...190.......200...-----....210.......220...--....230....------------.-----------..240.-------......250.-----......260.......270--------------........280---.--------.......290.......300.......310.----..------....320..---.....330-........340...-----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MVQF
T
K
QAKI
N
Q
E
H
L
Q
T
W
Q
-DRGL--
I
I
P
D
L
V
R
A
D
R
Y
L
S
F
--
I
--
G
Y
Y
R
---------L
S
A
Y
T
---I
P
F
Q
Q
IVT
T
--
P
S
T
V
L
H
Q
FKAN--T
T
F
D
D
V
L
N
L
Y
I
F
D
R
E
L
R
L
L
I
M
-
D
A
I
E
R
-----
I
E
V
A
I
R
A
Q
I
C
N
V
L
C
HLSG
N
--
A
F
-
W
Y
T----D
E
Q
H-------F
N
H
---
H
Y
A
H
M
R
-------
L
L
A
---
S
I
E
R
Q
L
L
----
D
E
K
E
R
L
I
R
D
E
KAIDKR----------PLSQA
D
K
D
V
L
K
D
K
V
R
K
E
N
F
L
R
----
H
Y
L
S
KYDSP-KLPPS
W
M
M
I
E
MLTWG
E
L
S
H
-----
L
Y
VGLKS
N
Q
A
K
K
Q
I
A
Q
NLG
L
--
H
A
E
V
L
E
S
W
L
K
S
------------
L
-----------
N
D
V
R
N
L
-------
C
A
H
H
S
R
L
W
N
K
-----EHG
R
S
I
KIP
T
S
N
A
I
Q
W
L
Q---------------Q
P
I
I
LSN
T
A
I
----
R
--------
Y
EK
R
T
Y
M
L
L
V
A
I
Q
T
L
L
YKISPN
S
T
W
A
K
R
L
K
D
----
L
I
------
E
QYPSLSKA---NMGM
P
E
L--WHQD
P
F
W
Q
Q
A
LQQN-----------------------------------------
20
Fugue
66.94
17%
38
- C1 -
-
4X4W
3
TRNT1_HUMAN
A:
[1-409]
----
M
F
T
M
K
L
Q
S
P
E
F
Q
S
L
F
-
T
E
G
L
K
S
L
T
E
L
F
V
K
E
N
H
E
L
R
I
--
A
--
G
G
A
V
---------
R
D
L
L
N
G
V
K
P
Q
D
I
D
F
A
T
T
AT
P
T
Q
M
K
E
M
F
Q
S
A
G
I
R
M
I
N
G
T
I
T
A
R
L
H
E
E
N
F
E
I
T
T
L
-----
R
-----
I
D
V
T
T
D
G
A
------
E
V
E
F
T
--
T
D
-
W
Q
K
----
D
A
E
R
-------
R
D
L
---
T
I
N
S
M
---------
F
L
---
G
F
D
G
T
L
F
----
D
-
Y
F
N
G
Y
E
D
L
K
N
K
K
V
R
----------
F
V
G
H
A
K
Q
R
I
Q
E
D
Y
L
R
I
L
R
Y
F
R
----
F
Y
G
R
I
V
D
K
P
G
D
H
D
P
E
T
L
E
A
I
A
E
N
A
K
G
L
A
G
-----
I
S
G
E
R
I
W
V
E
L
K
K
I
L
V
G
N
-----
H
V
N
H
L
I
H
L
I
Y
D
------------
L
-----------
D
V
A
P
Y
I
GLPANAS
L
E
E
F
D
K
V
S
K
N
-----
V
D
G
F
S
P
K
P
V
T
L
L
A
S
L
F
K
V
---------------
Q
D
D
V
T
K
L
D
L
R
LKIA
K
--------
E
E
K
N
L
G
L
F
I
V
K
N
R
K
D
L
I
K
A
T
D
S
S
D
P
L
K
P
Y
Q
D
----
F
I
I
D
SD
A
T
T
R
V
C
E
L
L
K
Y
Q
GE
H
C
L
L
K
E
M
Q
Q
W
S
I
P
P
F
P
V
S
G
H
D
I
R
K
V
GISS
G
K
E
I
G
A
L
L
Q
Q
L
R
E
Q
W
K
K
S
GYQME
K
D
E
L
L
S
Y
I
K
K
T
L
21
Fugue
51.54
12%
-2
- C1 -
-
4MSX
-
SAD1_YEAST
A:
[63-482]
---
Y
A
Y
L
E
T
V
V
R
E
K
L
D
-
F
D
-
S
E
K
I
--
C
C
I
T
L
S
P
L
N
V
Y
C
C
L
--
V
CG
H
Y
Y
Q
G
RHEKS
P
A
F
I
H
S
I
D
---
E
N
H
H
V
F
L
N
L
--
T
S
L
K
F
Y
M
L
P
Q
N
--
V
Q
I
L
H
D
G
E
V
Q
L
L
N
S
I
K
F
A
A
Y
P
-
T
Y
C
P
K
-----
D
L
E
D
F
P
R
Q
C
F
D
L
S
N
R
T
Y
L
N
--
G
F
I
G
F
T
----
N
A
A
T
-------
Y
D
Y
---
A
H
S
V
L
L
-------
L
I
S
H
M
V
P
V
R
D
H
F
L
L
N
HF
D
N
Q
G
E
F
I
K
R
L
S
I
C
V
K
K
----------
I
W
S
---
P
K
L
F
K
H
H
L
S
V
D
D
F
V
S
----
Y
L
K
V
R
E
G
L
N
-
L
N
P
I
D
P
R
L
F
L
L
W
L
F
N
K
I
C
S
S
S
N
D
L
K
S
I
L
N
H
S
C
K
G
K
V
K
I
A
K
S
E
S
V
T
G
K
V
I
V
K
P
F
W
V
L
T
------------
L
D
L
P
EFSPFEDG
N
S
V
D
D
L
P
------
Q
I
N
I
T
K
L
L
T
K
-----
F
T
K
T
V
F
E
L
T
R
L
P
Q
F
L
I
F
H
F
NRFDRNSDHPVKNR
N
Q
T
L
V
E
F
S
S
E
----
L
--------
E
I
L
H
V
K
Y
R
L
K
A
N
V
V
H
V
V
I
G
D
E
K
S
H
W
I
T
Q
L
Y
D
NKSE
K
W
------
I
E
I
D
G
I
N
T
T
---
E
R
E
A
E
L
L
--
F
L
K
E
T
F
I
Q
V
W
E
K
Q
E
-----------------------------------------
18
Fugue
49.64
12%
-71
- C1 -
-
4K1C
6
VCX1_YEAST
A:
[27-406]
T
A
W
R
A
A
V
Y
D
L
Q
Y
I
L
K
A
S
P
L
-
N
F
L
L
--
V
F
V
P
L
G
L
I
W
G
H
F
Q
L
S
H
T
--
L
T
F
L
---------
F
N
F
L
A
---
I
I
P
L
A
A
I
L
A
--
N
A
T
E
E
L
A
D
K
A
G
--
N
T
I
G
G
L
L
N
A
T
F
G
N
A
V
E
L
I
V
S
I
-
I
A
L
K
K
GQ
V
R
I
V
Q
A
S
M
L
G
S
L
L
S
N
L
L
L
V
L
G
L
--
C
F
-
I
F
G
GYNR
V
Q
Q
T
-------
F
N
Q
T
A
A
Q
T
M
S
S
L
-------
L
A
I
---
A
C
A
S
L
L
I
----
P
A
A
F
R
A
T
L
P
F
I
D
G
K
I
L
----------
E
L
S
R
G
T
S
I
V
I
L
I
V
Y
V
L
F
L
Y
F
Q
L
GSH
H
A
L
F
E
Q
Q
E
E
-
E
T
D
E
V
M
S
T
I
S
R
N
P
H
H
S
L
S
V
-----
K
S
S
L
V
I
L
L
G
T
T
V
I
I
S
F
C
A
D
F
--
L
V
G
T
I
D
N
V
V
E
S
T
GLS
K
T
F
I
G
L
IV
I
-----------
P
I
V
G
N
A
-------
A
E
H
V
T
S
V
L
V
A
M
K
DK
M
D
L
A
L
G
V
A
I
G
S
S
L
Q
V
A
L
F
V
---------------
T
P
F
M
V
L
V
G
W
M
----
I
DVPMTLNF
S
T
F
E
T
A
T
L
F
I
A
V
F
L
S
N
Y
L
I
L
D
G
E
S
N
W
L
E
G
V
M
----
S
L
------
A
M
Y
I
L
I
A
M
A
---
F
F
Y
Y
P
D
E
---------------------------------------------------------
6
PsiBlast_PDB
45.03
27%
-69
- C2 -
-
3Q0T
1
DPP4_HUMAN
A:
[625-730]
-----------------------------------------------
Y
Y
---------
D
S
V
Y
T
---
E
R
Y
M
G
L
-
P
T
--
P
E
D
N
L
D
H
Y
R
N
S
--
T
V
M
S
R
A
E
N
---
F
K
Q
V
E
Y
L
L
I
H
G
T
A
D
D
N
-----
V
H
F
Q
Q
S
A
Q
I
S
K
A
L
V
D
V
G
V
D
F
Q
A
M
-
W
Y
T
----
D
E
D
H
GIAS
S
T
A
H
Q
H
---
I
Y
T
H
M
S
H
F
I
K
Q
C
F
S
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
44.74
27%
-66
- C2 -
-
3NOX
1
DPP4_HUMAN
A:
[625-730]
-----------------------------------------------
Y
Y
---------
D
S
V
Y
T
---
E
R
Y
M
G
L
-
P
T
--
P
E
D
N
L
D
H
Y
R
N
S
--
T
V
M
S
R
A
E
N
---
F
K
Q
V
E
Y
L
L
I
H
G
T
A
D
D
N
-----
V
H
F
Q
Q
S
A
Q
I
S
K
A
L
V
D
V
G
V
D
F
Q
A
M
-
W
Y
T
----
D
E
D
H
GIAS
S
T
A
H
Q
H
---
I
Y
T
H
M
S
H
F
I
K
Q
C
F
S
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
44.56
27%
-69
- C2 -
-
3SX4
1
DPP4_HUMAN
A:
[625-730]
-----------------------------------------------
Y
Y
---------
D
S
V
Y
T
---
E
R
Y
M
G
L
-
P
T
--
P
E
D
N
L
D
H
Y
R
N
S
--
T
V
M
S
R
A
E
N
---
F
K
Q
V
E
Y
L
L
I
H
G
T
A
D
D
N
-----
V
H
F
Q
Q
S
A
Q
I
S
K
A
L
V
D
V
G
V
D
F
Q
A
M
-
W
Y
T
----
D
E
D
H
GIAS
S
T
A
H
Q
H
---
I
Y
T
H
M
S
H
F
I
K
Q
C
F
S
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
43.95
27%
-67
- C2 -
-
3SWW
1
DPP4_HUMAN
A:
[625-730]
-----------------------------------------------
Y
Y
---------
D
S
V
Y
T
---
E
R
Y
M
G
L
-
P
T
--
P
E
D
N
L
D
H
Y
R
N
S
--
T
V
M
S
R
A
E
N
---
F
K
Q
V
E
Y
L
L
I
H
G
T
A
D
D
N
-----
V
H
F
Q
Q
S
A
Q
I
S
K
A
L
V
D
V
G
V
D
F
Q
A
M
-
W
Y
T
----
D
E
D
H
GIAS
S
T
A
H
Q
H
---
I
Y
T
H
M
S
H
F
I
K
Q
C
F
S
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
42.10
21%
-226
- C2 -
-
1WTY
-
?
A:
[73-91]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
W
L
E
------------
M
-----------
L
E
L
R
N
L
-------
T
N
H
T
Y
D
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
36.04
17%
-40
* C2 *
-
1VDF
-
COMP_RAT
A:
[1-46]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
----
D
L
A
P
Q
M
L
R
E
L
Q
E
T
N
A
A
------------
L
Q
D
V
R
E
L
L
R
Q
Q
V
K
E
I
T
F
L
K
----
N
T
V
M
E
C
D
A
C
-
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
35.24
14%
-33
- C1 -
-
2MV3
-
YME1_YEAST
A:
[96-183]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
A
----
V
S
H
A
M
L
A
T
R
E
Q
E
A
N
K
D
----------
L
T
S
P
D
A
Q
A
A
F
Y
K
L
L
L
Q
S
N
Y
P
Q
----
Y
V
V
S
R
F
E
T
P
-
G
I
A
S
S
---------
P
E
C
M
E
-----
L
Y
M
E
A
L
Q
R
I
G
R
H
S
E
A
D
A
V
R
Q
--
N
L
E
H
H
H
H
H
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
34.71
31%
-126
- C2 -
-
2B91
-
IL4_HUMAN
A:
[54-113]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
-------
Y
S
H
---
H
E
K
D
T
R
-------
C
L
G
---
A
T
A
Q
Q
F
H
----
R
H
K
Q
-
L
I
R
D
L
K
A
L
D
R
N
L
W
G
L
A
GLN
S
C
P
V
K
E
A
N
Q
S
T
L
------
E
N
F
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
29.91
23%
-80
- C2 -
-
1YLM
-
YUTE_BACSU
A:
[84-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
G
D
E
L
K
K
------------
L
-----------
I
A
Y
R
K
T
-------
L
V
Q
Q
Y
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
28.21
13%
-6
- C2 -
-
3EFG
1
SLYX_XANCP
A:
[8-58]
---------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
Q
E
-------
L
E
A
---
R
L
V
E
L
E
-------
T
R
L
---
S
F
Q
E
Q
A
L
----
T
E
L
S
E
A
L
A
D
A
R
L
T
G
A
R
----------
N
A
E
L
I
R
H
L
L
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
27.99
24%
-112
- C2 -
-
2KXE
-
DP2S_PYRHO
A:
[31-63]
-------
K
F
S
L
I
E
L
I
K
F
A
K
-
S
R
E
T
--
F
I
I
D
D
E
I
A
N
E
F
L
K
S
--
I
--
G
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
25.86
32%
-204
* C1 *
-
2FQC
1
A:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------
F
P
R
P
R
I
C
N
L
A
C
R
A
-
G
I
--
G
H
-
K
Y
-----
P
F
C
H
-------
C
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
25.31
37%
-37
- C2 -
-
5TEB
-
?
A:
[122-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
--
P
K
E
Q
V
E
R
W
R
K
A
------------
L
-----------
E
D
V
A
T
I
-------
A
G
Y
H
S
H
K
W
C
D
-----
E
A
E
M
I
E
K
I
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
23.68
7%
-107
- C2 -
-
3BRJ
1
?
C:
[72-119]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
L
K
L
L
F
G
L
G
V
--
L
P
D
D
I
Y
H
D
I
E
D
------------
I
-----------
I
K
L
K
N
H
-------
L
N
S
D
A
S
D
Y
E
F
-----
T
D
P
N
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
21.38
7%
-111
- C2 -
-
3BRJ
1
?
B:
[72-115]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
L
K
L
L
F
G
L
G
V
--
L
P
D
D
I
Y
H
D
I
E
D
------------
I
-----------
I
K
L
K
N
H
-------
L
N
S
D
A
S
D
Y
E
F
-----
T
D
P
N
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
18.17
17%
152
- C2 -
-
1WWP
-
?
B:
[72-94]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
A
R
L
A
L
G
------------
M
-----------
V
D
D
R
S
L
-------
T
V
H
T
Y
N
E
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
17.41
16%
-30
- C2 -
-
1WIR
-
ANM3_MOUSE
A:
[24-69]
------
L
F
A
S
A
E
E
T
F
S
H
C
K
L
E
H
Q
F
--
N
I
D
S
-
M
V
H
K
H
G
L
E
F
--
Y
--
G
Y
I
K
---------
L
I
N
F
I
---
R
L
K
N
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------