@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VNB1: (2017-11-13 )
MNISDNTPQGQLSSQQFYRQYSANALLPELDWQSIFPHSKLSETHIKALNTIYQCAVPLALNVFHDLNFDVFAPAAYHPQGLGLFDKLAQQEENFLKVLTAESENLDHETRHQIWSMLLRSGAVLVFKAWLGHVKLGENQLDMTQFDELSDLLFIKTPPHQLAERLHVDEKAKLDHIFLMYGNDIFLDRFNSLETVALFVDLGVYDAAFLSLRDDCVAEYLKSKGYVTQEQIDDLQCALNPLYCDSLTPKQDCLA
Atome Classification :
(20 SA)
------------------.......--..10---.........----------20..--.-...--..30-.....-.--..40........50--------------.....--...60..-------------...-...70....--------------.....80.---.....--------.-------------.90....-....------100.--......110.--..-------...---.120...-----....130........140..--..------...150......------.160.......170.------......180..-----.....-----190..--.....-----200------.--.-.-.....-.210-----------------.....--....220.--..------....230.......240-...--......250...----------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------MNISDNT--PQG----Q
L
S
S
Q
Q
F
Y
R
----------
Q
YSA--N-ALL--PEL
D
-
W
Q
SIF-P--HSKL
S
E
T
H
I
K
A
L
N
T
--------------
I
Y
Q
C
A
--
V
P
L
A
L
N
V
-------------
F
HD-LNFD-VFAP--------------AAYHPQGL---
G
L
F
D
K
--------
L
-------------
A
Q
Q
E
E
N
F
-
L
K
V
L------TAES--ENL
D
H
E
T
R
H
Q
--
I
W
-------
S
M
L
---
L
RS
G
A
V
L
-----
V
F
K
A
W
L-G
H
V
KLGENQL
D
M
T
--
Q
F
------
D
ELS
D
L
L
F
I
KT
P
------
P
H
Q
L
A
E
R
LHVDEKAK------L
D
H
I
F
L
M
YG
N
D
-----
I
F
L
D
R-----FNSL
E
--
T
V
A
L
F
-----
V
--------D--L-G-
V
Y
D
A
A
-
F
L
-------------------
S
L
R
D
D
--
C
V
A
E
Y
L
K
S--KG------YV
T
Q
E
Q
I
D
D
L
Q
C
ALN---PLY--CDSLT
P
K
Q
DCLA----------------
46
Fugue
62.60
19%
2
* C4 *
-
5TNV
-
?
A:
[21-326]
-----MYSAHTW
P
I
A
A
N
M
L
G
F
G
N
R
A
--
P
D
G
GHIK
D
A
P
A
G
V
W
A
K
----------
Q
L
R
Q
--
V
-
R
E
L
GF
D
H
I
D
-
P
T
D
A
W
V
P
--
L
A
A
L
S
D
S
R
I
E
E
F
R
T
--------------
V
L
A
D
E
GL
A
I
S
S
I
S
M
-------------
T
R
S
-
S
I
V
D
-
V
E
N
G
--------------
E
K
N
L
A
D
A
H
---
R
L
I
D
L
--------
A
-------------
P
S
F
G
A
T
I
-
V
N
T
G
------
F
M
Q
A
--
L
T
P
E
Q
E
K
Q
I
W
--
F
W
LVQ
G
H
V
D
D
P
A
---
L
R
D
L
A
I
E
-----
R
V
R
E
L
G
-
D
H
A
R
T
N
G
I
Q
L
S
L
E
--
M
Y
E
DTYIG
T
P
D
D
A
V
A
F
I
K
D
V
------
D
H
D
-
A
V
G
L
N
P
D
L
G
N
L
V
R
LHRP
M
P
H
P
S
E
M
Y
A
K
V
-----
L
P
Y
S
N
-----
F
W
H
I
K
--
N
Y
S
R
D
-----
F
--------
D
PA
T
-
G
-
A
Y
S
S
A
-
P
L
-------------------
P
L
K
Y
--------------
G
------
Y
V
N
Y
R
Q
I
I
R
L
A
L
E
L
G
Y
T
G
P
F
C
--
C
E
H
Y
G
S
D
S
L
G
V
C
A
E
N
R
E
Y
I
L
Q
V
L
T
S
A
L
A
51
Fugue
55.05
18%
-15
- C3 -
-
4PW8
-
T23O_HUMAN
A:
[26-367]
I
Y
G
N
Y
L
HL
E
K
V
L
N
AQEL
Q
S
E
T
K
G
N
K
--
I
H
D
----
E
H
L
F
I
I
T
H
Q
----------
A
Y
E
L
W
F
K
-
Q
I
L
--
W
E
L
D
S
V
R
E
I
F
-
Q
N
G
H
V
R
D
E
R
N
M
L
K
V
V
S
R
--------------
M
H
R
V
S
--
V
I
L
K
L
L
V
Q
Q
F
S
I
L
E
T
MT
A
L
D
F
N
D
-
F
R
E
Y
-
L
S
P
A
--------------
S
G
F
Q
S
L
Q
F
---
R
L
L
E
N
--------
K
I
GVLQE
E
N
E
L
L
L
K
S
E
Q
E
K
T
L
-
L
E
L
V
------
E
A
W
L
--
E
R
T
P
G
L
E
P
H
G
FN
F
W
-------
G
K
L
E
K
N
I
T
R
G
L
E
E
-----
E
F
I
R
I
Q
-
A
K
E
E
S
E
E
K
E
E
Q
V
A
--
E
F
------
Q
K
Q
K
E
V
L
L
S
L
F
D
------
E
K
R
H
E
H
L
L
S
K
G
E
R
-
R
------
L
S
Y
R
A
L
Q
G
A
L
M
-----
I
Y
F
Y
R
EE---
P
R
F
Q
V
--
P
F
Q
L
L
-----
T
--------
S
--
L
-
M
-
D
I
D
S
L
-
M
T
-------------------
K
W
R
Y
N
H
V
C
M
V
H
R
M
L
G
--
S
R
------
Y
K
V
F
V
D
L
F
N
L
S
T
Y
L
I
---
P
-----
R
H
W
I
P
K
M
N
-------------------
47
Fugue
52.33
18%
14
- C4 -
-
4OHC
3
?
A:
[10-230]
-------------TGYD
R
Q
S
I
S
D
T
T
--
A
K
I
----
L
L
E
V
Q
A
V
H
F
----------------
N
-
A
E
K
--
P
F
I
F
-
T
S
G
W
A
-
S
--
P
V
Y
I
D
C
R
K
L
I
S
Y
P
R
--------------
V
R
R
A
L
--
M
E
M
A
E
T
T
-------------
I
T
R
D
I
G
F
E
Q
I
D
A
V
--------------
A
G
G
E
T
A
G
I
---
P
F
A
A
W
--------
I
-------------
A
D
R
M
M
V
P
-
M
Q
Y
V
------
R
K
K
P
--
K
G
F
G
R
N
A
Q
-----------------------------------
I
E
-
G
H
L
E
E
G
S
R
V
L
L
V
E
--
D
L
------
T
T
D
S
R
------
S
------
K
I
N
F
V
N
A
L
R
T
-
A
G
A
T
------
V
N
H
C
F
V
L
F
H
Y
N
-----
I
F
K
-----------
E
--
S
V
S
V
L
-----
K
--------
D
--
I
-
D
-
V
D
L
H
A
-
L
A
-------------------
T
W
W
D
----
V
L
R
V
A
K
A
--
S
G
------
Y
F
E
T
K
T
L
D
E
V
E
K
F
L
H
---
A
P
A
--
E
W
S
A
A
H
G
G
--------------------
50
Fugue
50.67
21%
5
- C4 -
-
4Q3K
1
?
A:
[20-260]
----------------Q
G
M
N
I
S
K
I
T
IN
Q
H
V
----
G
V
T
L
T
C
Y
V
Q
----------
D
V
S
Q
--
E
M
S
N
M
--
S
K
R
P
-
A
M
L
I
F
-
P
--
G
G
G
Y
Q
F
C
S
D
R
E
---------------------
A
--
E
P
I
A
L
S
Y
-------------
L
A
K
--
G
Y
N
-
A
F
V
L
--------------
R
-
Y
S
V
K
E
H
---
A
V
F
P
R
--------
P
-------------
L
I
D
A
E
D
A
-
L
S
Y
L
------
K
D
N
A
--
H
A
L
-
H
I
N
P
D
K
--
I
A
-------
V
I
G
---
F
S
A
G
G
H
L
-----
A
T
T
L
A
T
E
G
K
V
R
P
N
A
V
V
L
G
Y
P
--
A
L
------
I
R
H
E
K
Y
W
N
F
P
T
P
K
V
D
QQT
P
E
M
F
V
F
H
T
F
E
D
D
L
V
P
------
L
S
H
P
L
Y
I
V
E
E
--------
L
S
K
-----
A
N
I
P
V
--
E
F
H
L
F
-----
K
--------
S
----
G
-
V
H
G
----
L
-------------------
S
L
G
N
K
--
I
V
S
N
G
L
---------------
D
K
M
I
E
D
D
V
Q
V
W
F
---
D
L
S
--
C
R
W
L
D
K
V
L
D
L
------------------
54
Fugue
50.05
9%
41
- C4 -
-
1QWG
-
PSLS_METJA
A:
[1-251]
----------------MK
A
F
E
F
L
Y
E
--
D
F
Q
----
R
G
L
T
V
V
L
D
K
----------
G
L
P
P
--
K
-
F
V
E
--
D
Y
L
K
-
V
C
G
D
Y
I
D
--
F
V
K
F
G
W
G
T
S
A
V
I
D
-----------------
R
D
V
--
V
K
E
K
I
N
Y
-------------
Y
K
D
-
W
G
I
K
-
V
Y
P
G
--------------
G
T
L
F
E
Y
A
Y
S
K
G
K
F
D
E
F
--------
L
-------------
N
E
C
E
K
L
G
-
F
E
A
V
------
E
I
S
D
GS
S
D
I
S
L
E
E
R
N
N
--
A
I
-------
K
R
A
---
K
D
N
G
F
M
V
-----
L
T
E
V
G
K
-
K
M
P
D
K
D
K
Q
L
-------------------------
T
------
I
D
D
R
I
K
L
I
N
F
D
L
D
A
G
------
A
D
Y
V
I
I
E
G
R
E
S
GKGKG
L
F
D
K
E
GK---
V
K
E
N
E
--
L
D
V
L
A
-----
K
--------
N
--
V
-
D
-
I
N
K
V
I
-
F
E
-------------------
A
P
Q
K
S
--
Q
Q
V
A
F
I
L
K
--
F
G
SS
V
N
L
A
N
I
A
F
D
E
V
I
S
L
E
T
L
R
R
---
G
L
R
--
G
D
T
F
G
K
V
---------------------
52
Fugue
49.32
19%
11
- C2 -
-
4NXT
1
MID51_HUMAN
A:
[9-345]
-----------------D
L
K
K
S
R
L
R
--
M
S
L
----
Q
E
K
L
L
T
Y
Y
R
N
RAAIP
A
G
E
Q
A
R
A
K
--
Q
-
A
A
V
--
D
I
C
A
-
E
L
R
S
F
-
L
--
R
A
K
L
P
D
M
P
L
R
D
M
Y
L
S
G
SLYDDLQVVTAD
H
I
Q
L
I
--
V
P
L
V
L
E
Q
-------------
N
L
W
-
S
C
I
P
-
G
E
D
T
IMNVPG
F
F
L
V
R
R
E
N
P
E
Y
F
P
R
G
S
---
S
Y
W
D
R
CVVGGYLS
P
-------------
K
T
V
A
D
T
F
-
E
K
V
V
A
G
S
IN
W
P
A
I
G
--
S
L
L
D
Y
V
I
R
P
A
--
P
P
-------
P
E
A
---
L
T
L
E
V
Q
Y
ERD
K
H
L
F
I
D
F
L
-
P
S
V
T
L
G
D
T
V
L
V
A
K
PH
R
L
------
A
Q
Y
D
N
L
W
R
L
S
L
R
------
P
A
E
T
A
R
L
R
A
L
D
Q
A
D
S
------
G
C
R
S
L
C
L
K
I
L
K
-----
A
I
C
K
S
-----
T
P
A
L
G
HL
T
A
S
Q
L
-----
T
--------
N
--
V
-
I
-
L
H
L
A
Q
E
E
A
-------------------
D
W
S
P
D
--
M
L
A
D
R
F
L
Q
A
L
R
G
------
L
I
S
Y
L
E
A
G
V
L
P
S
A
L
N
---
P
K
V
NL
F
A
E
L
T
P
E
E
I
D
E
L
G
Y
T
L
Y
C
S
LSEPEVLL-
18
PsiBlast_PDB
42.03
28%
-196
- C5 -
-
2QQ8
-
A:
[234-301]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
------
T
L
Y
S
--
K
S
L
P
L
D
L
A
C
R
--
I
W
-------
D
V
F
---
C
R
D
G
E
E
F
-----
L
F
R
T
A
L
-
G
I
L
K
L
F
E
D
I
L
T
K
M
--
D
F
------
I
H
M
A
Q
F
L
-
T
R
L
P
------
E
D
L
P
A
E
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
39.40
22%
-116
- C4 -
-
2MN4
-
?
A:
[1-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
--------
T
-------------
P
E
Q
R
E
F
L
-
P
E
I
L
------
A
E
I
I
--
A
N
L
D
---
P
T
K
--
I
L
-------
E
E
L
---
L
R
R
G
-
L
L
-----
T
P
A
E
L
Q
-
E
V
L
D
L
K
T
---
P
E
E
--
Q
A
------
K
K
L
I
D
F
I
L
-
K
L
S
------
P
A
D
V
Q
A
R
I
N
V
L
R
A
H
G
------
Y
Q
A
L
A
D
K
L
N
K
Y
-----
L
T
L
E
----------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
39.27
24%
-9
- C5 -
-
3HZS
1
MGT_STAAW
A:
[101-205]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
R
V
E
K
Q
Y
N
------
K
N
E
I
L
S
F
Y
L
N
N
-----
I
Y
F
G
D
N----
Q
Y
T
L
E
--
G
A
A
N
H
Y
FGTT
V
NKNSTTMS
H
--
I
-
T
-
V
L
Q
S
A
-
I
L
A
S
K
V
N
A
P
SVYNINNMS
E
N
F
T
Q
R
V
S
--
T
N
L
E
K
M
K
Q
--
Q
N
------
Y
I
N
E
T
Q
Y
Q
Q
A
M
----------------------------------------
32
HHSearch
37.41
24%
-79
- C5 -
-
3VMA
1
PBPB_ECOLI
A:
[256-360]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
M
A
L
I
M
D
A
R
Y
S
------
K
D
R
I
L
E
L
Y
M
N
E
-----
V
Y
L
G
Q
SGDNE
I
R
G
F
P
--
L
A
S
L
Y
-----
Y
FGRPVE--
E
--
L
-
S
-
L
D
Q
Q
A
-
L
L
V
G
M
V
KGASIYNPWRN
P
K
L
A
L
E
R
R
N
--
L
V
L
R
L
L
Q
Q
--
Q
Q
------
I
I
D
Q
E
L
Y
D
M
L
S
----------------------------------------
42
HHSearch
37.04
33%
-329
- C5 -
-
1ZL0
1
LDC_PSEAE
A:
[91-112]
------------------------------------------------------
Y
G
C
--
G
-
Q
L
L
--
P
G
L
D
-
W
G
R
L
Q
A
A
--
S
P
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
36.11
25%
-59
- C5 -
-
5HLB
1
PBPB_ECOLI
A:
[236-338]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
L
I
M
D
A
R
Y
S
------
K
D
R
I
L
E
L
Y
M
N
E
-----
V
Y
L
G
Q
SGD
N
E
I
R
G
F
P
--
L
A
S
L
Y
-----
Y
FGRPVE--
E
--
L
-
S
-
L
D
Q
Q
A
-
L
L
V
G
M
VKGASIYNPWRN
P
K
L
A
L
E
R
R
N
--
L
V
L
R
L
L
Q
Q
--
Q
Q
------
I
I
D
Q
E
L
Y
D
M
L
S
----------------------------------------
44
HHSearch
35.92
17%
-217
- C5 -
-
2NSN
-
NOD1_HUMAN
A:
[38-61]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
--
C
L
V
D
N
L
L
K
--
N
D
------
Y
F
S
A
E
D
A
E
I
V
C
A
C
--------------------------------------
36
HHSearch
33.77
33%
-157
* C5 *
-
2BA2
-
Y010_MYCPN
A:
[6-20]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
------
Y
V
T
H
K
Q
L
D
E
K
L
K
N
--------------------------------------
28
HHSearch
31.45
26%
-217
- C5 -
-
3CRD
-
CRADD_HUMAN
A:
[26-48]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
Q
Y
L
Y
Q
--
E
G
------
I
L
T
E
N
H
I
Q
E
I
N
A
Q
T
-------------------------------------
17
PsiBlast_PDB
31.29
34%
-90
- C5 -
-
1YAC
-
YCAC_ECOLI
A:
[121-167]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
A
--------
L
-------------
S
A
I
E
E
G
F
D
V
F
V
V
------
T
D
A
S
--
G
T
F
N
E
I
T
R
H
S
--
A
W
-------
D
R
M
---
S
Q
A
G
A
Q
L
-----
M
--
T
W
F
-
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
30.56
26%
-54
- C5 -
-
5L87
1
?
A:
[10-52]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-----
E
K
R
V
S
--
N
A
V
E
F
-----
L
--------
L
--
D
-
S
R
V
R
R
T
P
------------------------
T
S
S
--
K
V
H
-
F
L
K
S
--
K
G
------
L
-
S
A
E
E
I
C
E
A
F
----------------------------------------
23
HHSearch
30.39
26%
-58
- C5 -
-
5AON
-
?
B:
[7-49]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-----
E
K
R
V
S
--
N
A
V
E
F
-----
L
--------
L
--
D
S
R
-
V
R
R
T
P
------------------------
T
S
S
--
K
V
H
-
F
L
K
S
--
K
G
------
L
-
S
A
E
E
I
C
E
A
F
----------------------------------------
34
HHSearch
30.22
17%
-130
- C5 -
-
4I16
-
CAR11_MOUSE
A:
[23-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
--
K
L
T
P
Y
L
R
Q
--
C
K
------
V
I
D
E
Q
D
E
D
E
V
L
N
A
--------------------------------------
27
HHSearch
30.07
31%
-39
- C5 -
-
4BXU
-
PEX14_HUMAN
A:
[14-56]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-----
E
P
L
I
A
--
T
A
V
K
F
-----
L
--------
Q
--
N
S
R
-
V
R
Q
S
P
------------------------
L
A
T
--
R
R
A
-
F
L
K
K
--
K
G
------
L
-
T
D
E
E
I
D
M
A
F
----------------------------------------