@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VNK1: (2017-11-16 )
MAELLTLARPYAKAAFAYASEQGATDNWSNALQVLSAAVQDEAFSAYLNRPEHTPAEQVKLFAKVLGEDQSQAVSNFLTLLADNDRLVLLPEIAAEYEQLKSQNNNNVDVVIESAFPLTAEQEQLLKSALEKRFNSTVTVSVEVKPELIAGVVIRAGDQVIDDSALNKLEKMRTRLLA
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-.......20........30....---...------.-40........50--..---...-----------....60......-.-.70........80........90----.........100.-......110.......120......---..130.----.---.....140......---.150.......160.......170......------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
E
L
L
T
L
A
R
P
Y
A
-
K
A
A
F
AYASEQGATD
N
W
S
N
A
L
Q
V
L
---
S
A
A
------
V
-
Q
D
E
A
F
S
A
Y
LNR---PE---HT
P
-----------
A
E
Q
V
K
L
F
A
K
V
LG-E-
D
Q
S
Q
A
V
S
N
F
L
T
L
LADN
D
R
L
V
L
L
-----
P
E
I
A
A
E
Y
E
Q
L
KSQ-NNN
N
V
D
V
V
I
ESAFPL
T
A
E
-
Q
E
Q
L
L
K
---
S
A
L
E
K
R----F---NS
T
V
T
V
S
V
E
V
K
P
E
L
---
I
A
G
V
V
I
RAGDQVI
D
D
S
A
L
N
K
L
E
K
M
R
T
R
LLA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
79.56
33%
-54
- C2 -
-
5T4O
-
ATPD_ECOLI
L:
[3-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
M
L
A
F
A
---
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
ALA
P
E
----
T
L
-----------
A
E
S
---
F
I
A
V
A
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
A
E
V
D
V
I
S
A
A
A
L
S
E
Q
-
Q
L
A
K
I
S
---
A
A
M
E
K
R
----
L
---
S
R
K
V
K
L
N
A
K
I
D
K
S
V
---
M
A
G
V
I
I
R
A
G
D
M
V
I
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.93
33%
-27
- C2 -
-
5T4P
-
ATPD_ECOLI
L:
[3-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
M
L
A
F
A
---
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
ALA
P
E
----
T
L
-----------
A
E
S
---
F
I
A
V
A
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
A
E
V
D
V
I
S
A
A
A
L
S
E
Q
-
Q
L
A
K
I
S
---
A
A
M
E
K
R
----
L
---
S
R
K
V
K
L
N
A
K
I
D
K
S
V
---
M
A
G
V
I
I
R
A
G
D
M
V
I
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.76
33%
-47
- C2 -
-
5T4Q
-
ATPD_ECOLI
L:
[3-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
M
L
A
F
A
---
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
ALA
P
E
----
T
L
-----------
A
E
S
---
F
I
A
V
A
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
A
E
V
D
V
I
S
A
A
A
L
S
E
Q
-
Q
L
A
K
I
S
---
A
A
M
E
K
R
----
L
---
S
R
K
V
K
L
N
A
K
I
D
K
S
V
---
M
A
G
V
I
I
R
A
G
D
M
V
I
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
76.93
31%
-72
- C2 -
-
2A7U
-
ATPD_ECOLI
B:
[1-105]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
M
L
A
F
A
---
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
ALA
P
E
----
T
L
-----------
A
E
S
---
F
I
A
V
C
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.74
31%
-62
- C2 -
-
1ABV
-
ATPD_ECOLI
A:
[1-105]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
M
L
A
F
A
---
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
ALA
P
E
----
T
L
-----------
A
E
S
---
F
I
A
V
C
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.10
28%
-16
- C2 -
-
5LQX
-
?
U:
[11-190]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
F
G
L
D
G
T
Y
A
-
T
A
L
F
S
A
S
A
K
D
S
S
I
E
K
T
F
Q
S
V
Q
K
L
---
S
S
T
------
I
S
K
D
A
K
V
A
Q
V
L
S
N
---
P
A
LSL
N
S
R
-----------
K
E
V
V
S
V
L
S
K
E
L
K
-
L
-
E
P
--
V
V
S
N
L
L
T
V
L
A
E
N
N
R
L
S
L
F
-----
D
S
I
A
K
Q
F
S
V
L
N
D
A
-
Y
N
G
V
V
E
A
T
V
V
S
A
K
P
L
D
S
K
I
L
N
R
L
T
K
---
S
I
T
N
S
K
----
Y
VGP
G
K
T
L
K
-----------------------------
A
S
K
V
N
K
L
N
K
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
68.64
28%
3
- C2 -
-
5LQZ
-
?
U:
[11-190]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
F
G
L
D
G
T
Y
A
-
T
A
L
F
S
A
S
A
K
D
S
S
I
E
K
T
F
Q
S
V
Q
K
L
---
S
S
T
------
I
S
K
D
A
K
V
A
Q
V
L
S
N
---
P
A
LSL
N
S
R
-----------
K
E
V
V
S
V
L
S
K
E
L
K
-
L
-
E
P
--
V
V
S
N
L
L
T
V
L
A
E
N
N
R
L
S
L
F
-----
D
S
I
A
K
Q
F
S
V
L
N
D
A
-
Y
N
G
V
V
E
A
T
V
V
S
A
K
P
L
D
S
K
I
L
N
R
L
T
K
---
S
I
T
N
S
K
----
Y
VGP
G
K
T
L
K
-----------------------------
A
S
K
V
N
K
L
N
K
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
67.87
30%
-7
- C2 -
-
5T4O
-
ATPD_ECOLI
L:
[3-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
I
T
V
A
R
P
Y
A
-
K
A
A
F
D
F
A
V
E
H
Q
S
V
E
R
W
Q
D
-
M
L
A
F
A--
A
E
V
------
T
-
K
N
E
Q
M
A
E
L
L
S
G
---
A
L
---
A
P
E
-----------
T
L
A
E
S
F
I
-
A
V
A
G
-
E
-
Q
L
D
E
N
G
Q
N
L
I
R
V
M
A
E
N
G
R
L
N
A
L
-----
P
D
V
L
E
Q
F
I
H
L
R
A
V
-
S
E
A
T
A
E
V
D
V
I
S
A
A
A
L
S
E
Q
-
Q
L
A
K
I
S
---
A
A
M
E
K
R
----
L
---
S
R
K
V
K
L
N
A
K
I
D
K
S
V
---
M
A
G
V
I
I
R
A
G
D
M
V
I
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
65.73
26%
0
- C- -
-
1F99
3
PHCB_POLUR
B:
[5-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
K
V
V
A
----
Q
A
D
A
R
G
E
F
L
S
N
T
Q
I
D
A
L
L
A
I
V
-----
S
E
G
N
K
R
L
D
V
V
N
K
I
-
T
N
N
A
S
A
I
V
T
N
A
A
R
A
L
F
A
E
-
Q
P
Q
L
I
S
PGG
N
A
Y
T
S
R
----
R
---
M
A
A
C
L
R
D
M
E
I
V
L
R
Y
---
V
S
Y
A
M
I
A
G
D
A
S
V
L
D
D
R
C
L
N
G
L
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.01
28%
14
- C2 -
-
5LQY
-
?
U:
[11-190]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
F
G
L
D
G
T
Y
A
-
T
A
L
F
S
A
S
A
K
D
S
S
I
E
K
T
F
Q
S
V
Q
K
L
---
S
S
T
------
I
S
K
D
A
K
V
A
Q
V
L
S
N
---
P
A
LSL
N
S
R
-----------
K
E
V
V
S
V
L
S
K
E
L
K
-
L
-
E
P
--
V
V
S
N
L
L
T
V
L
A
E
N
N
R
L
S
L
F
-----
D
S
I
A
K
Q
F
S
V
L
N
D
A
-
Y
N
G
V
V
E
A
T
V
V
S
A
K
P
L
D
S
K
I
L
N
R
L
T
K
---
S
I
T
N
S
K
----
Y
VGP
G
K
T
L
K
-----------------------------
A
S
K
V
N
K
L
N
K
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
62.86
26%
13
- C2 -
-
5LQX
-
?
U:
[11-191]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
F
G
L
D
G
T
Y
A
-
T
A
L
F
S
A
S
A
K
D
S
S
I
E
K
T
F
Q
S
V
Q
K
L
S--
S
T
I
------
S
-
K
D
A
K
V
A
Q
V
L
S
N
---
P
A
---
L
S
L
-----------
N
S
R
K
E
V
V
S
V
L
S
K
-
E
L
K
L
E
P
V
V
S
N
L
L
T
V
L
A
E
N
N
R
L
S
L
F
-----
D
S
I
A
K
Q
F
S
V
L
N
D
A
-
Y
N
G
V
V
E
A
T
V
V
S
A
K
P
L
D
S
K
-
I
L
N
R
L
T
---
K
S
I
T
N
S
KYVG
P
---
G
K
T
L
K
-----------------------------
A
S
K
V
N
K
L
N
K
V
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.60
29%
-23
- C2 -
-
5DN6
-
ATPD_PARDP
H:
[13-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
R
Y
A
-
Q
A
L
F
D
L
V
R
D
S
G
G
I
D
A
L
S
S
Q
I
D
D
L
---
A
S
A
YDASQD
L
-
R
D
L
T
L
S
P
L
Y
D
R
---
Q
Q
---
Q
E
A
-----------
A
--
V
G
A
L
S
E
R
M
G
----
L
S
A
E
L
A
N
T
L
R
L
L
A
R
N
R
R
L
F
T
L
-----
P
Q
F
V
A
K
L
R
N
L
I
A
D
-
A
K
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
60.75
26%
37
- C2 -
-
5LQZ
-
?
U:
[11-191]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
F
G
L
D
G
T
Y
A
-
T
A
L
F
S
A
S
A
K
D
S
S
I
E
K
T
F
Q
S
V
Q
K
L
S--
S
T
I
------
S
-
K
D
A
K
V
A
Q
V
L
S
N
---
P
A
---
L
S
L
-----------
N
S
R
K
E
V
V
S
V
L
S
K
-
E
L
K
L
E
P
V
V
S
N
L
L
T
V
L
A
E
N
N
R
L
S
L
F
-----
D
S
I
A
K
Q
F
S
V
L
N
D
A
-
Y
N
G
V
V
E
A
T
V
V
S
A
K
P
L
D
S
K
-
I
L
N
R
L
T
---
K
S
I
T
N
S
KYVG
P
---
G
K
T
L
K
-----------------------------
A
S
K
V
N
K
L
N
K
V
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
60.47
17%
-
- C- -
-
4FGQ
-
?
A:
[56-244]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
L
I
S
V
E
K
I
Q
K
-
L
A
Q
S
Y
Q
G
D
T
R
K
R
F
T
A
W
G
N
L
I
D
S
L
KKK
P
V
K
------
I
-
Q
L
E
K
V
N
S
F
F
N
Q
---
F
N
---
Y
E
T
DPITGASDD
Y
W
K
S
P
V
E
F
I
V
D
G
G
G
-
D
-
C
E
D
F
A
I
I
K
Y
F
T
L
V
A
V
G
-----
V
-----
P
S
D
Q
L
R
I
T
Y
A
A
S
L
-
T
L
N
Q
A
H
M
V
L
S
F
-
Y
P
T
P
E
S
-
E
P
L
I
L
D
---
S
L
E
S
K
I
----
L
---
K
A
S
A
R
P
D
L
K
P
V
Y
S
F
---
N
A
E
G
L
W
L
A
K
G
---
D
S
K
S
L
G
K
W
D
A
L
M
K
R
M
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
59.62
28%
8
- C2 -
-
5DN6
-
ATPD_PARDP
H:
[11-115]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
A
G
R
Y
A
-
Q
A
L
F
D
L
V
R
D
S
G
G
I
D
A
L
S
S
Q
I
D
D
L
A--
S
A
Y
------
D
-
A
S
Q
D
L
R
D
L
T
L
S
---
P
L
---
Y
D
R
-----------
Q
Q
Q
E
A
A
V
G
A
L
S
E
-
R
M
G
L
S
A
E
L
A
N
T
L
R
L
L
A
R
N
R
R
L
F
T
L
-----
P
Q
F
V
A
K
L
R
N
L
I
A
D
-
A
K
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
57.21
23%
39
- C2 -
-
5DN6
-
ATPD_PARDP
H:
[6-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
A
S
I
S
A
D
I
A
G
R
Y
A
-
Q
A
L
F
D
L
V
R
D
S
G
G
I
D
A
L
S
S
Q
I
D
D
L
---
A
S
A
------
Y
D
A
S
Q
D
L
R
D
L
T
L
S
---
P
L
---
Y
D
R
-----------
Q
Q
Q
E
A
A
V
G
A
L
S
E
-
R
M
G
L
S
A
E
L
A
N
T
L
R
L
L
A
R
N
R
R
L
F
T
L
-----
P
Q
F
V
A
K
L
R
N
L
I
A
D
-
A
K
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
53.90
23%
27
- C2 -
-
2BO5
-
ATPO_BOVIN
A:
[9-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
I
Y
G
I
E
G
R
Y
A
-
T
A
L
Y
S
A
A
S
K
Q
N
K
L
E
Q
V
E
K
E
L
L
R
V
G
--
Q
I
L
------
K
--
E
P
K
M
A
A
S
L
L
N
---
P
Y
---
V
K
R
-----------
S
V
K
V
K
S
L
S
D
M
T
A
K
E
-
K
F
S
P
L
T
S
N
L
I
N
L
L
A
E
N
G
R
L
T
N
T
-----
P
A
V
I
S
A
F
S
T
M
M
S
V
-
H
R
G
E
V
P
C
T
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
45.84
18%
41
- C2 -
-
2EYQ
3
MFD_ECOLI
A:
[5-1150]
PEQYR
Y
T
L
P
V
K
AG
E
Q
R
L
L
GELTGA
A
C
A
T
L
V
A
E
I
A
E
R
HA
G
P
V
V
L
I
A
PD
M
Q
N
A
L
R
L
H
D
E
I
S
Q
F
T
D
Q
M
V
M
N
LADWETLPYDSFSPH
Q
D
I
I
S
S
R
L
S
T
L
Y
Q
LPTMQ
R
G
V
L
I
V
P
V
N
T
L
M
Q
R
V
C
P
H
S
F
L
H
G
H
A
L
V
M
K
KGQRLS
R
D
A
L
R
T
Q
L
D
S
A
G
Y
R
H
V
DQVMEHG
E
Y
A
T
R
GA
L
L
D
L
FPMGSE
L
P
Y
R
L
D
F
F
DDEID
S
L
R
V
F
D
VDSQRTLEEVE
A
I
N
L
L
P
AHEFPTD
K
A
A
I
E
L
F
R
S
Q
W
R
D
T
F
E
V
K
RDPEH
I
Y
Q
Q
V
S
K
GTLPAGIEYW
Q
P
L
F
F
SEPLPPLFSYFPAN
T
L
L
V
N
T
G
D
L
E
T
S
A
E
R
F
Q
A
D
T
L
A
R
F
E
N
R
GVDPM
R
P
L
L
P
PQSLWLR
V
D
E
L
F
S
E
L
K
N
W
P
R
V
Q
L
K
TEHLPTKAA
N
A
N
L
GFQKLPDLAVQAQQKAPL
D
A
L
R
K
F
L
E
T
FD
G
P
V
V
F
S
V
ES
E
G
R
R
E
A
L
G
E
L
L
A
R
I
K
I
A
P
Q
R
I
MRLDEASDR
G
R
Y
L
M
I
GAAE
H
G
F
V
D
TVRN
L
A
L
I
C
ESDLLG
E
R
V
A
R
R
RQDSRRTIN
P
D
T
L
I
R
NLAELHIG
Q
P
V
V
H
LEH
G
V
G
R
Y
A
G
M
T
T
L
E
A
GG
I
T
G
E
Y
L
M
L
T
Y
A
NDA
K
L
Y
V
P
VSSLHLIS
R
Y
A
G
GAEENAPLHKLGGD
A
W
S
R
A
R
Q
K
A
A
E
K
V
R
D
V
A
A
E
L
L
D
I
Y
A
Q
R
A
A
K
E
G
F
A
F
K
H
D
R
E
Q
Y
Q
L
F
C
D
S
F
P
F
E
---
T
T
P
------
D
-
Q
A
Q
A
I
N
A
V
L
S
D
---
M
C
---
Q
P
L
-----------
A
M
D
R
L
V
C
G
D
V
-
G
-
F
-
G
K
T
E
V
A
M
R
A
A
F
L
A
V
D
N
H
K
Q
V
A
V
L
V
PT
T
L
L
A
Q
Q
H
Y
D
N
F
R
D
R
F
A
N
W
P
V
R
I
E
M
I
S
R
F
R
S
A
K
E
-
Q
T
Q
I
L
A
---
E
V
A
E
G
K
----
I
---
D
I
L
I
G
T
H
K
L
L
Q
S
D
V
KFK
D
L
G
L
L
I
V
D
E
E
H
R
F
G
V
R
H
K
E
R
I
K
A
M
R
A
N
V
D
I
L
T
L
T
ATPIP
R
T
L
N
M
A
M
SGM
R
D
L
S
I
IATPPARR
L
A
V
K
T
F
V
R
E
YD
S
M
V
V
R
E
A
I
L
R
E
I
L
R
G
G
Q
V
Y
Y
L
Y
NDVEN
I
Q
K
A
A
E
R
L
A
E
L
V
PE
A
R
I
A
I
G
H
G
QMR
E
R
E
L
E
R
V
M
N
D
F
H
H
QRFN
V
L
V
C
TTIIETGIDIPTAN
T
I
I
I
ERADHFG
L
A
Q
L
H
Q
L
R
G
R
V
G
R
S
H
H
Q
A
Y
A
W
LLTPHPKAMT
T
D
A
Q
K
R
L
E
A
I
A
S
LEDLGA
G
F
A
L
A
T
H
D
L
E
I
R
G
A
G
E
L
L
G
E
E
Q
S
G
S
M
E
T
IG
F
S
L
Y
M
E
L
L
E
N
A
V
D
A
L
K
A
GREPSLEDLTSQQ
T
E
V
E
LR
M
P
S
L
L
P
DDFIPD
V
N
T
R
L
S
F
Y
K
R
I
A
S
AKT
E
N
E
L
E
E
I
K
V
E
L
I
D
R
FGLLP
D
P
A
R
T
L
L
D
I
A
R
L
R
Q
Q
A
Q
K
L
GIR
K
L
E
G
N
EK
G
G
V
I
E
F
A
EKNHVN
P
A
W
L
I
G
L
L
Q
KQPQH
Y
R
L
D
G
PT
R
L
K
F
I
Q
DLSE
R
K
T
R
I
E
W
V
R
Q
F
M
R
E
L
E
E
N
AI
12
PsiBlast_PDB
44.57
27%
-40
- C2 -
-
1EAG
1
CARP2_CANAX
A:
[154-246]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
S
L
Y
L
N
S
---
P
D
---
A
A
T
-----------
G
Q
I
I
--
F
G
G
V
-----
D
N
A
K
Y
S
G
S
L
I
A
L
P
V
T
S
D
R
E
L
R
I
-----
S
L
G
S
V
E
V
S
G
-
K
T
I
-
N
T
D
N
V
D
V
L
L
D
S
G
T
T
I
T
Y
L
-
Q
Q
D
L
A
D
---
Q
I
I
-
K
A
----
F
---
N
G
K
L
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.83
27%
-64
- C2 -
-
3PVK
3
CARP2_CANAX
A:
[154-253]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
S
L
Y
L
N
S
---
P
D
---
A
A
T
-----------
G
Q
I
I
--
F
G
G
V
-----
D
N
A
K
Y
S
G
S
L
I
A
L
P
V
T
S
D
R
E
L
R
I
-----
S
L
G
S
V
E
V
S
G
-
K
T
I
-
N
T
D
N
V
D
V
L
L
D
S
G
T
T
I
T
Y
L
-
Q
Q
D
L
A
D
---
Q
I
I
-
K
A
----
F
---
N
G
K
L
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------