@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VNK4: (2017-11-17 )
MSSGRIIQIIGAVIDVEFERTSVPKIYDALQVDGTETTLEVQQQLGDGVVRTIAMGSTEGLKRGLTVTSTNAPISVPVGTATLGRIMDVLGRPIDEAGPVATEERLPIHRQAPSYAEQAASTDLLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDENGKGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASSGIYPAIDPLDSTSRQLDPLVVGQEHYEIARAVQNVLQRYKELKDIIAILGMDELAEEDKLVVYRARKIQRFFSQPFHVAEVFTGAPGKLVPLKETIRGFKGLLAGEYDHIPEQAFYMVGGIDEVIAKAEKL
Atome Classification :
(21 SA)
.........10........20........30..---..---..--..40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.....------..------200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSSG
R
I
I
Q
I
I
G
A
V
I
D
V
E
FERTSV
P
K
I
Y
D
A
LQVD---GT---
E
T
--
T
L
E
V
Q
Q
Q
LG
D
G
V
V
R
T
I
AMG
S
T
E
G
LKRG
L
T
V
TSTNA
P
I
S
V
PV
G
T
A
T
L
G
R
I
M
D
V
LGRPIDEAGPVATEERLPIHRQA
P
S
Y
A
E
Q
AAS
T
D
L
L
E
T
G
I
K
V
I
D
L
LCPFAKGGK
V
G
L
FGGAGVGKT
V
N
M
M
E
L
I
N
N
I
A
K
A
HSG
L
S
V
F
AGVGERTREGN
D
F
Y
H
EMKDS
N
V
------
L
D
------
K
V
A
M
V
YGQMNEPPG
N
R
L
R
V
A
LTG
L
T
M
A
E
Y
F
RDEKDENGKG
R
D
V
L
L
F
VDN
I
Y
R
Y
TLAG
T
E
V
S
A
L
L
GRMPSAVGYQP
T
L
A
E
E
M
G
V
L
Q
E
R
I
TSTKSG
S
I
T
S
I
Q
A
V
Y
VPADDLTDPSPA
T
T
F
A
H
L
D
A
T
V
V
L
SR
D
I
ASSGIYPAIDPLDSTSRQLD
P
L
V
VG
Q
E
H
Y
E
I
A
R
A
V
Q
N
V
L
Q
R
Y
K
E
L
K
D
I
I
A
I
LG
M
D
E
LAEED
K
L
V
V
Y
R
A
R
K
I
Q
R
F
F
SQP
F
H
V
A
E
V
FTGAPGK
L
V
P
L
K
E
T
I
R
G
F
K
G
LLAGEYDHI
P
E
Q
A
F
Y
M
VG
G
I
D
E
V
I
A
K
AEKL
191
HHSearch
99.18
80%
0
- C- -
-
3OAA
-
ATPB_ECOLI
V:
[2-459]
--
T
G
K
I
V
Q
V
I
G
A
V
V
D
V
E
F
P
Q
D
A
V
P
R
V
Y
D
A
L
E
V
Q
---
N
G
NE-
R
L
--
V
L
E
V
Q
Q
Q
L
G
G
G
I
V
R
T
I
A
M
G
S
S
D
G
L
R
R
G
L
D
V
K
D
L
E
H
P
I
E
V
P
V
G
E
A
T
L
G
R
I
M
N
V
L
G
E
P
V
D
M
K
G
E
I
G
E
E
E
R
W
A
I
H
R
A
A
P
S
Y
E
E
L
S
N
S
Q
E
L
L
E
T
G
I
K
V
I
D
L
M
C
P
F
A
K
G
G
K
V
G
L
F
G
G
A
G
V
G
K
T
V
N
M
M
E
L
I
R
N
I
A
I
E
H
S
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
F
Y
H
E
M
T
D
S
N
V
------
I
D
------
K
V
S
L
V
Y
G
Q
M
N
E
P
P
G
N
R
L
R
V
A
L
T
G
L
T
M
A
E
K
F
R
D
------
E
G
R
D
V
L
L
F
V
D
N
I
Y
R
Y
T
L
A
G
T
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
E
E
M
G
V
L
Q
E
R
I
T
S
T
K
T
G
S
I
T
S
V
Q
A
V
Y
V
P
A
D
D
L
T
D
P
S
P
A
T
T
F
A
H
L
D
A
T
V
V
L
S
R
Q
I
A
S
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
Q
L
D
P
L
V
V
G
Q
E
H
Y
D
T
A
R
G
V
Q
S
I
L
Q
R
Y
Q
E
L
K
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
V
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
F
V
A
E
V
F
T
G
S
P
G
K
Y
V
S
L
K
D
T
I
R
G
F
K
G
I
M
E
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
S
I
E
E
A
V
E
K
A
K
K
L
197
HHSearch
94.37
81%
-93
- C5 -
-
4Q4L
-
ATPB1_BURTA
A:
[28-484]
-
V
E
G
K
I
V
Q
C
I
G
A
V
I
D
V
E
F
P
R
E
S
M
P
K
I
Y
D
A
L
I
L
E
---
G
S
---
E
L
--
T
L
E
V
Q
Q
Q
L
G
D
G
V
V
R
T
I
C
L
G
A
---
L
R
R
G
V
V
V
K
N
T
G
N
P
I
S
V
P
V
G
K
P
T
L
G
R
I
M
D
V
L
G
R
P
I
D
E
A
G
P
I
E
S
E
N
K
R
S
I
H
Q
K
A
P
A
F
D
E
L
S
P
S
T
E
L
L
E
T
G
I
K
V
I
D
L
I
C
P
F
A
K
G
G
K
V
G
L
F
G
G
A
G
V
G
K
T
V
N
M
M
E
L
I
N
N
I
A
K
E
H
G
G
Y
S
V
F
A
G
V
-------
N
D
F
Y
H
E
M
K
D
S
N
V
------
L
D
------
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
N
R
L
R
V
A
L
T
G
L
T
M
A
E
H
F
R
D
------
E
G
L
D
V
L
F
F
V
D
N
I
Y
R
F
T
L
A
G
T
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
E
E
M
G
K
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
V
Q
A
V
Y
V
P
A
-------------
H
L
D
A
T
V
V
L
S
R
D
I
A
S
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
Q
I
D
P
N
V
I
G
E
E
H
Y
S
I
T
R
R
V
Q
Q
T
L
Q
R
Y
K
E
L
R
D
I
I
A
I
L
G
M
D
E
L
S
P
E
D
K
L
S
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
V
F
T
G
S
P
G
K
Y
V
P
L
K
E
T
I
R
G
F
K
M
I
V
D
G
E
C
D
H
L
P
E
Q
A
F
Y
M
V
G
T
I
D
E
A
F
E
K
A
K
K
I
1
PsiBlast_PDB
94.19
80%
-94
- C5 -
-
4Q4L
-
ATPB1_BURTA
A:
[30-484]
---
G
K
I
V
Q
C
I
G
A
V
I
D
V
E
F
P
R
E
S
M
P
K
I
Y
D
A
L
I
L
E
---
G
S
---
E
L
--
T
L
E
V
Q
Q
Q
L
G
D
G
V
V
R
T
I
C
L
G
A
---
L
R
R
G
V
V
V
K
N
T
G
N
P
I
S
V
P
V
G
K
P
T
L
G
R
I
M
D
V
L
G
R
P
I
D
E
A
G
P
I
E
S
E
N
K
R
S
I
H
Q
K
A
P
A
F
D
E
L
S
P
S
T
E
L
L
E
T
G
I
K
V
I
D
L
I
C
P
F
A
K
G
G
K
V
G
L
F
G
G
A
G
V
G
K
T
V
N
M
M
E
L
I
N
N
I
A
K
E
H
G
G
Y
S
V
F
A
G
V
-------
N
D
F
Y
H
E
M
K
D
S
N
V
------
L
D
------
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
N
R
L
R
V
A
L
T
G
L
T
M
A
E
H
F
R
D
E
------
G
L
D
V
L
F
F
V
D
N
I
Y
R
F
T
L
A
G
T
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
E
E
M
G
K
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
V
Q
A
V
Y
V
P
A
-------------
H
L
D
A
T
V
V
L
S
R
D
I
A
S
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
Q
I
D
P
N
V
I
G
E
E
H
Y
S
I
T
R
R
V
Q
Q
T
L
Q
R
Y
K
E
L
R
D
I
I
A
I
L
G
M
D
E
L
S
P
E
D
K
L
S
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
V
F
T
G
S
P
G
K
Y
V
P
L
K
E
T
I
R
G
F
K
M
I
V
D
G
E
C
D
H
L
P
E
Q
A
F
Y
M
V
G
T
I
D
E
A
F
E
K
A
K
K
I
5
PsiBlast_PDB
82.79
69%
-
- C5 -
-
2QE7
-
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
RPQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
6
PsiBlast_PDB
81.61
69%
-0
- C5 -
-
5HKK
2
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
RPQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
195
HHSearch
81.50
71%
-1
- C5 -
-
5IK2
1
?
F:
[1-462]
M
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
---
R
P
QGG
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
-----
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
37
PsiBlast_CBE
81.36
69%
-1
- C5 -
-
5HKK
1
?
F:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
RPQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
12
PsiBlast_PDB
81.17
69%
-
- C5 -
-
1QO1
-
ATPB_BOVIN
D:
[9-473]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
194
HHSearch
81.16
71%
-1
- C5 -
-
5IK2
1
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
---
R
P
Q
G
G
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
-----
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
32
PsiBlast_CBE
81.06
69%
-1
- C5 -
-
5IK2
1
?
F:
[1-462]
M
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
RPQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
7
PsiBlast_PDB
80.85
69%
-1
- C5 -
-
5IK2
1
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
R
PQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
38
PsiBlast_CBE
79.68
69%
-1
- C5 -
-
5HKK
3
?
E:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
L
P
D
I
Y
N
A
I
T
I
E
RPQ
G
G
---
T
L
--
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
------
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
19
PsiBlast_PDB
79.53
69%
10
- C5 -
-
1W0J
3
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
R
L
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
201
HHSearch
79.08
71%
10
- C5 -
-
2JDI
2
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
ET-
R
L
--
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
INLKDA
T
S
------
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
-----
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
108
PsiBlast_CBE
78.88
69%
10
- C5 -
-
4ASU
1
ATPB_BOVIN
D:
[11-475]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
R
L
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
10
PsiBlast_PDB
78.77
69%
9
- C5 -
-
1EFR
1
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
20
PsiBlast_PDB
78.76
69%
9
- C5 -
-
1W0K
3
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
R
L
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
9
PsiBlast_PDB
78.72
69%
10
- C5 -
-
1COW
1
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
79
PsiBlast_CBE
78.66
69%
10
- C5 -
-
1W0K
2
ATPB_BOVIN
F:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
75
PsiBlast_CBE
78.65
69%
10
- C5 -
-
2JDI
2
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
55
PsiBlast_CBE
77.44
69%
11
- C5 -
-
2JJ2
24
ATPB_BOVIN
M:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
D
E
-
G
L
P
P
I
L
N
A
L
E
V
Q
---
G
R
---
E
T
RL
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
------
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
-----
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L