@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VNX9: (2017-11-18 )
MSYFGTDGIRGKFGQMPITPEFALKLGFAAGKVLKRTSPKNKPLVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLPTPAIAHLTRALHAHAGIVISASHNPYFDNGIKFFSSEGKKLPDSLQEEINKELEKDLFIEDTANLGKSVRVTDANGRYIEFCKSTFPYHFDLNNLKIVVDCAHGAAYSVGPSVFRELGAKVVALYNEPDGLNINENCGSTHPESLQKAVVEHGADLGIAFDGDADRVVMVDKFGNLIDGDHILYILATQAKNKPAGVVGTVMSNMALEVALEKANVGFVRAKVGDRYVLQALEENGWVTGGEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVHDFKLYPQVLVNVRLEQMLDPYSIPALVAEFNKAEEQLKGRGRILIRKSGTEPVIRVMVEGDNEQEVKTLAEHLANAVRSQAQVA
Atome Classification :
(20 SA)
.........10....-....20........30........40..-......50........60........70........80........90........100.......110.......120.......130...-.---...140.......150.......160.......170.......180.......190.......200.......210.......220.......230--........240.......250.......260.......--270--.----.---......280.......290.......300.......310.......320.......330.-......340.......350.......360.......370.....---..380.-......---390.......400-----------.........410.......420.......430.......440...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSYFGTDGIRGKFGQ-MPI
T
P
E
F
A
L
K
L
G
F
AA
G
K
V
L
KRTSPKNK
P
-
L
V
V
LGKDTR
L
S
G
Y
I
L
E
S
A
L
Q
AGLNA
A
G
V
Y
V
H
L
LGPLP
T
P
A
I
A
H
L
T
R
A
L
H
AHA
G
I
V
I
SASHNPYFDN
G
I
K
F
F
SSEGKKL
P
D
S
L
Q
E
E
I
N
K
E
L
E
K
-D---LFIE
D
T
ANLGK
S
V
R
V
TDANG
R
Y
I
E
F
C
KSTF
P
Y
H
F
DLNN
L
K
I
V
V
DCAHGAAYSV
G
P
S
V
F
R
E
LGA
K
V
V
A
L
YNEPDGLNINENCGST
H
P
E
S
L
Q
K
A
V
V
E---HGAD
L
G
I
A
FDGDA
D
R
V
V
M
V
D
KFGNLIDGD
H
I
L
Y
I
L
ATQ--A-K--N----K---PA
G
V
V
G
T
V
M
S
N
M
A
L
E
V
A
L
EKA
N
V
G
F
V
R
AKVG
D
R
Y
V
L
Q
A
L
EENGWVTGGEPSG
H
I
L
T
LDKS-TT
G
D
A
I
I
A
A
L
Q
V
L
T
V
M
V
EQ
N
K
A
L
H
E
L
V
H
D
F
K
L
Y
P
Q
V
L
V
N
V
R
L
E
Q---MLDPYS-
I
P
A
L
V
A
---
E
F
N
K
A
E
E
Q
LKG-------------R
G
R
I
L
I
RKSGTE
P
V
I
R
V
M
VEGD
N
E
Q
E
V
K
T
L
A
E
H
L
A
N
A
V
R
S
QAQVA
24
HHSearch
97.44
43%
-31
- C1 -
-
3PDK
-
GLMM_BACAN
A:
[24-467]
-
K
Y
F
G
T
D
G
V
R
G
V
A
N
K
-
E
-
L
T
P
E
L
A
F
K
I
G
R
F
G
G
Y
V
L
T
K
D
--
T
D
R
P
-
K
V
I
I
G
R
D
T
R
I
S
G
H
M
L
E
G
A
L
V
A
G
L
L
S
T
G
A
E
V
M
R
L
G
V
I
S
T
P
G
V
A
Y
L
T
K
A
L
D
A
Q
A
G
V
M
I
S
A
S
H
N
P
V
Q
D
N
G
I
K
F
F
G
S
D
G
F
K
L
T
D
E
Q
E
A
E
I
E
A
L
L
D
K
E
V
DE-
L
P
R
P
T
G
T
N
L
G
Q
V
S
D
Y
F
E
G
G
Q
K
Y
L
Q
Y
I
K
Q
T
V
E
E
--
D
F
S
G
L
H
I
A
L
D
C
A
H
G
A
T
S
S
L
A
P
Y
L
F
A
D
L
E
A
D
I
S
T
M
G
T
S
P
N
G
M
N
I
N
D
G
V
G
S
T
H
P
E
V
L
A
E
L
V
K
E
---
K
G
A
D
I
G
L
A
F
D
G
D
G
D
R
L
I
A
V
D
E
K
G
N
I
V
D
G
D
Q
I
M
F
I
C
A
K
Y
--
M
K
E
--
T
----
G
QLK
H
N
T
V
V
S
T
V
M
S
N
L
G
F
Y
K
A
L
E
A
N
G
I
T
S
D
K
T
A
V
G
D
R
Y
V
M
E
E
M
K
R
G
G
Y
N
L
G
G
E
Q
S
G
H
I
I
L
L
D
Y
I
-
T
T
G
D
G
M
L
S
A
L
Q
L
V
N
I
M
K
M
T
K
K
P
L
S
E
L
A
G
E
M
T
K
F
P
Q
L
L
V
N
V
R
V
T
D
---
K
-
K
L
A
L
E
N
E
K
I
K
E
---
I
I
R
V
V
E
E
E
M
N
G
-------------
D
G
R
I
L
V
R
P
S
G
T
E
P
L
I
R
V
M
A
E
A
P
T
Q
E
V
C
D
A
Y
V
H
R
I
V
E
V
V
K
A
E
V
G
--
1
PsiBlast_PDB
96.15
43%
-33
- C1 -
-
3PDK
-
GLMM_BACAN
A:
[25-465]
--
Y
F
G
T
D
G
V
R
G
-
V
A
N
-
K
E
L
T
P
E
L
A
F
K
I
G
R
F
G
G
Y
V
L
--
T
K
D
T
D
R
P
-
K
V
I
I
G
R
D
T
R
I
S
G
H
M
L
E
G
A
L
V
A
G
L
L
S
T
G
A
E
V
M
R
L
G
V
I
S
T
P
G
V
A
Y
L
T
K
A
L
D
A
Q
A
G
V
M
I
S
A
S
H
N
P
V
Q
D
N
G
I
K
F
F
G
S
D
G
F
K
L
T
D
E
Q
E
A
E
I
E
A
L
L
D
K
-
E
VDE
L
P
R
P
T
G
T
N
L
G
Q
V
S
D
Y
F
E
G
G
Q
K
Y
L
Q
Y
I
K
Q
T
V
--
E
E
D
F
S
G
L
H
I
A
L
D
C
A
H
G
A
T
S
S
L
A
P
Y
L
F
A
D
L
E
A
D
I
S
T
M
G
T
S
P
N
G
M
N
I
N
D
G
V
G
S
T
H
P
E
V
L
A
E
L
V
K
E
---
K
G
A
D
I
G
L
A
F
D
G
D
G
D
R
L
I
A
V
D
E
K
G
N
I
V
D
G
D
Q
I
M
F
I
C
A
K
Y
--
M
-
K
--
E
T
GQL
K
---
H
N
T
V
V
S
T
V
M
S
N
L
G
F
Y
K
A
L
E
A
N
G
I
T
S
D
K
T
A
V
G
D
R
Y
V
M
E
E
M
K
R
G
G
Y
N
L
G
G
E
Q
S
G
H
I
I
L
L
D
Y
I
-
T
T
G
D
G
M
L
S
A
L
Q
L
V
N
I
M
K
M
T
K
K
P
L
S
E
L
A
G
E
M
T
K
F
P
Q
L
L
V
N
V
R
V
T
D
K
K
L
A
L
E
N
E
K
-
I
K
E
I
I
------
R
V
V
E
E
E
M
N
G
-------------
D
G
R
I
L
V
R
P
S
G
T
E
P
L
I
R
V
M
A
E
A
P
T
Q
E
V
C
D
A
Y
V
H
R
I
V
E
V
V
K
A
E
----
23
HHSearch
94.34
43%
-26
- C1 -
-
3PDK
-
GLMM_BACAN
B:
[24-467]
-
K
Y
F
G
T
D
G
V
R
G
V
A
N
K
-
E
-
L
T
P
E
L
A
F
K
I
G
R
F
G
G
Y
V
L
T
K
D
--
T
D
R
P
-
K
V
I
I
G
R
D
T
R
I
S
G
H
M
L
E
G
A
L
V
A
G
L
L
S
T
G
A
E
V
M
R
L
G
V
I
S
T
P
G
V
A
Y
L
T
K
A
L
D
A
Q
A
G
V
M
I
S
A
S
H
N
P
V
Q
D
N
G
I
K
F
F
G
S
D
G
F
K
L
T
D
E
Q
E
A
E
I
E
A
L
L
D
K
E
V
DE-
L
P
R
P
T
G
T
N
L
G
Q
V
S
D
Y
F
E
G
G
Q
K
Y
L
Q
Y
I
K
Q
T
V
E
E
--
D
F
S
G
L
H
I
A
L
D
C
A
H
G
A
T
S
S
L
A
P
Y
L
F
A
D
L
E
A
D
I
S
T
M
G
T
S
P
N
G
M
N
I
N
D
G
V
G
S
T
H
P
E
V
L
A
E
L
V
K
E
---
K
G
A
D
I
G
L
A
F
D
G
D
G
D
R
L
I
A
V
D
E
K
G
N
I
V
D
G
D
Q
I
M
F
I
C
A
K
Y
--
M
K
E
--
T
----
G
QLK
H
N
T
V
V
S
T
V
M
S
N
L
G
F
Y
K
A
L
E
A
N
G
I
T
S
D
K
T
A
V
G
D
R
Y
V
M
E
E
M
K
R
G
G
Y
N
L
G
G
E
Q
S
G
H
I
I
L
L
D
Y
I
-
T
T
G
D
G
M
L
S
A
L
Q
L
V
N
I
M
K
M
T
K
K
P
L
S
E
L
A
G
E
M
T
K
F
P
Q
L
L
V
N
V
R
V
T
D
---
K
-
K
L
A
L
E
N
E
K
I
K
E
---
I
I
R
V
V
E
E
E
M
N
G
-------------
D
G
R
I
L
V
R
P
S
G
T
E
P
L
I
R
V
M
A
E
A
P
T
Q
E
V
C
D
A
Y
V
H
R
I
V
E
V
V
K
A
E
V
G
--
2
PsiBlast_PDB
84.05
42%
5
- C1 -
-
3I3W
-
GLMM_FRATT
A:
[4-441]
--
Y
F
G
T
D
G
I
R
G
E
V
A
N
-
S
T
I
T
V
E
F
T
Q
K
L
G
N
A
V
G
S
L
I
N
Q
---
K
N
Y
P
K
F
V
I
V
G
Q
D
T
R
S
S
G
G
F
L
K
F
A
L
V
S
G
L
N
A
A
G
I
D
V
L
D
L
G
V
V
P
T
P
V
V
A
F
M
T
V
K
H
R
A
A
A
G
F
V
I
T
A
S
H
N
K
F
T
D
N
G
I
K
L
F
S
S
N
G
F
K
L
D
D
A
L
E
E
E
V
E
D
M
I
D
G
-
D
---
F
I
Y
Q
P
Q
F
K
F
G
S
Y
K
I
L
A
N
A
I
D
E
Y
I
E
S
I
Y
S
R
F
A
K
F
V
N
Y
K
G
-
K
V
V
V
D
C
A
H
G
A
A
S
H
N
F
E
A
L
L
D
K
F
G
I
N
Y
V
S
I
A
S
N
P
D
G
L
N
I
N
V
G
C
G
A
T
C
V
S
N
I
K
K
A
V
K
E
---
Q
K
A
D
L
G
I
S
L
D
G
D
A
D
R
I
I
I
V
D
E
N
G
Q
E
I
D
G
D
G
I
L
N
I
L
A
Q
Y
--
S
-
D
IC
G
----
G
---
T
N
G
I
V
G
T
Q
M
T
N
M
S
Y
E
N
H
Y
R
A
N
K
I
P
F
I
R
S
K
V
G
D
R
Y
V
L
E
D
L
V
K
Y
G
Y
K
I
G
G
E
S
S
G
H
V
I
N
L
N
F
G
-
T
T
G
D
G
L
F
T
A
I
Q
L
L
A
I
F
S
Q
A
D
K
P
V
S
E
F
K
L
Q
G
E
L
M
Q
Q
T
L
I
N
V
P
L
T
K
---
K
V
A
R
E
D
-
L
Q
K
V
A
S
---
D
V
N
D
V
E
K
R
L
G
N
-------------
R
G
R
V
L
L
R
P
S
G
T
E
P
V
L
R
V
M
V
E
A
D
D
K
S
L
A
T
N
E
A
E
Y
L
V
E
K
V
K
Q
K
----
21
HHSearch
80.25
42%
13
- C1 -
-
3I3W
-
GLMM_FRATT
A:
[3-442]
-
K
Y
F
G
T
D
G
I
R
G
E
V
A
N
S
T
-
I
T
V
E
F
T
Q
K
L
G
N
A
V
G
S
L
I
N
Q
K
--
N
Y
P
K
-
F
V
I
V
G
Q
D
T
R
S
S
G
G
F
L
K
F
A
L
V
S
G
L
N
A
A
G
I
D
V
L
D
L
G
V
V
P
T
P
V
V
A
F
M
T
V
K
H
R
A
A
A
G
F
V
I
T
A
S
H
N
K
F
T
D
N
G
I
K
L
F
S
S
N
G
F
K
L
D
D
A
L
E
E
E
V
E
D
M
I
D
G
-
D
---
F
I
Y
Q
P
Q
F
K
F
G
S
Y
K
I
L
A
N
A
I
D
E
Y
I
E
S
I
Y
S
R
F
A
K
F
-
V
N
Y
K
G
K
V
V
V
D
C
A
H
G
A
A
S
H
N
F
E
A
L
L
D
K
F
G
I
N
Y
V
S
I
A
S
N
P
D
G
L
N
I
N
V
G
C
G
A
T
C
V
S
N
I
K
K
A
V
K
E
---
Q
K
A
D
L
G
I
S
L
D
G
D
A
D
R
I
I
I
V
D
E
N
G
Q
E
I
D
G
D
G
I
L
N
I
L
A
Q
Y
--
S
D
I
--
C
----
G
G--
T
N
G
I
V
G
T
Q
M
T
N
M
S
Y
E
N
H
Y
R
A
N
K
I
P
F
I
R
S
K
V
G
D
R
Y
V
L
E
D
L
V
K
Y
G
Y
K
I
G
G
E
S
S
G
H
V
I
N
L
N
F
G
-
T
T
G
D
G
L
F
T
A
I
Q
L
L
A
I
F
S
Q
A
D
K
P
V
S
E
F
K
L
Q
G
--
E
L
M
Q
Q
T
L
I
N
V
P
L
---
T
-
K
K
V
A
-
R
E
D
L
Q
K
V
A
S
D
V
N
D
V
E
K
R
L
G
N
-------------
R
G
R
V
L
L
R
P
S
G
T
E
P
V
L
R
V
M
V
E
A
D
D
K
S
L
A
T
N
E
A
E
Y
L
V
E
K
V
K
Q
K
L
---
22
HHSearch
79.81
42%
12
- C1 -
-
3I3W
-
GLMM_FRATT
B:
[3-442]
-
K
Y
F
G
T
D
G
I
R
G
E
V
A
N
S
T
-
I
T
V
E
F
T
Q
K
L
G
N
A
V
G
S
L
I
N
Q
K
--
N
Y
P
K
-
F
V
I
V
G
Q
D
T
R
S
S
G
G
F
L
K
F
A
L
V
S
G
L
N
A
A
G
I
D
V
L
D
L
G
V
V
P
T
P
V
V
A
F
M
T
V
K
H
R
A
A
A
G
F
V
I
T
A
S
H
N
K
F
T
D
N
G
I
K
L
F
S
S
N
G
F
K
L
D
D
A
L
E
E
E
V
E
D
M
I
D
G
-
D
---
F
I
Y
Q
P
Q
F
K
F
G
S
Y
K
I
L
A
N
A
I
D
E
Y
I
E
S
I
Y
S
R
F
A
K
F
-
V
N
Y
K
G
K
V
V
V
D
C
A
H
G
A
A
S
H
N
F
E
A
L
L
D
K
F
G
I
N
Y
V
S
I
A
S
N
P
D
G
L
N
I
N
V
G
C
G
A
T
C
V
S
N
I
K
K
A
V
K
E
---
Q
K
A
D
L
G
I
S
L
D
G
D
A
D
R
I
I
I
V
D
E
N
G
Q
E
I
D
G
D
G
I
L
N
I
L
A
Q
Y
--
S
D
I
--
C
----
G
G--
T
N
G
I
V
G
T
Q
M
T
N
M
S
Y
E
N
H
Y
R
A
N
K
I
P
F
I
R
S
K
V
G
D
R
Y
V
L
E
D
L
V
K
Y
G
Y
K
I
G
G
E
S
S
G
H
V
I
N
L
N
F
G
-
T
T
G
D
G
L
F
T
A
I
Q
L
L
A
I
F
S
Q
A
D
K
P
V
S
E
F
K
L
Q
G
--
E
L
M
Q
Q
T
L
I
N
V
P
L
---
T
-
K
K
V
A
-
R
E
D
L
Q
K
VAS
D
V
N
D
V
E
K
R
L
G
N
-------------
R
G
R
V
L
L
R
P
S
G
T
E
P
V
L
R
V
M
V
E
A
D
D
K
S
L
A
T
N
E
A
E
Y
L
V
E
K
V
K
Q
K
L
---
6
PsiBlast_PDB
79.48
26%
-29
- C1 -
-
1K2Y
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
A
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
12
PsiBlast_PDB
78.97
26%
-28
- C1 -
-
2FKF
1
ALGC_PSEAE
A:
[11-453]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTL
D
G
V
R
V
D
YP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
15
PsiBlast_PDB
78.96
26%
-30
- C1 -
-
1K35
-
ALGC_PSEAE
A:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTL
D
G
V
R
V
D
YP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
17
PsiBlast_PDB
78.70
26%
-28
- C1 -
-
3BKQ
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
G
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
10
PsiBlast_PDB
78.60
26%
-27
- C1 -
-
1PCM
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
4
PsiBlast_PDB
78.53
27%
-26
- C1 -
-
4MRQ
12
ALGC_PSEAE
A:
[4-446]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLD
G
V
R
V
D
Y
P
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
7
PsiBlast_PDB
78.44
26%
-27
- C1 -
-
1P5D
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
9
PsiBlast_PDB
78.42
26%
-28
- C1 -
-
1PCJ
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
11
PsiBlast_PDB
77.94
26%
-26
- C1 -
-
2FKM
1
ALGC_PSEAE
X:
[11-453]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
D
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
16
PsiBlast_PDB
77.93
26%
-26
- C1 -
-
4IL8
2
ALGC_PSEAE
A:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
A
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTL
D
G
V
R
V
D
YP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
14
PsiBlast_PDB
77.77
26%
-26
- C1 -
-
2H5A
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
8
PsiBlast_PDB
77.75
26%
-26
- C1 -
-
1P5G
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
18
PsiBlast_PDB
77.74
26%
-27
- C1 -
-
3C04
-
ALGC_PSEAE
A:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
V
K
A
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
V
V
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
G
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTL
D
G
V
R
V
D
YP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----
13
PsiBlast_PDB
77.35
26%
-28
- C1 -
-
2H4L
1
ALGC_PSEAE
X:
[12-454]
-
S
I
F
R
A
Y
D
I
R
G
V
V
G
D
-
T
-
L
T
A
E
T
A
Y
W
I
G
R
A
I
G
S
---
E
S
L
A
R
G
E
P
-
C
V
A
V
G
R
D
G
R
L
S
G
P
E
L
V
K
Q
L
I
Q
G
L
V
D
C
G
C
Q
V
S
D
V
G
M
V
P
T
P
V
L
Y
Y
A
A
N
V
L
E
G
K
S
G
V
M
L
T
G
S
H
N
P
P
D
Y
N
G
F
K
I
V
V
A
-
G
E
T
L
A
N
E
Q
I
Q
A
L
R
E
R
I
E
K
-
N
-------
D
L
A
S
G
V
G
S
V
E
Q
V
D
I
L
P
R
Y
F
K
Q
I
R
D
D
I
A
M
A
---
K
P
M
K
V
V
V
D
C
G
N
G
V
A
G
V
I
A
P
Q
L
I
E
A
L
G
C
S
V
I
P
L
Y
C
E
V
D
G
N
F
P
N
H
H
P
D
P
G
K
P
E
N
L
K
D
L
I
A
K
VKA
E
N
A
D
L
G
L
A
F
D
G
D
G
D
R
V
G
V
V
T
N
T
G
T
I
I
Y
P
D
R
L
L
M
L
F
A
K
D
VV
S
-
R
--
N
----
P
---
G
A
D
I
I
F
D
V
K
C
T
R
R
L
I
A
L
I
S
G
Y
G
G
R
P
V
M
W
K
T
G
H
S
L
I
K
K
K
M
K
E
T
G
A
L
L
A
G
E
M
S
G
H
V
F
F
K
E
R
W
F
G
F
D
D
G
I
Y
S
A
A
R
L
L
E
I
L
S
Q
D
Q
R
---
D
S
E
H
V
F
S
A
F
P
S
D
I
S
T
P
E
I
N
I
---
T
V
T
E
D
S
-
K
F
A
I
I
E
---
A
L
Q
R
D
A
Q
W
G
E
G
NITTLDGVRVDYP
K
G
W
G
L
V
R
A
S
N
T
T
P
V
L
V
L
R
F
E
A
D
T
E
E
E
L
E
R
I
K
T
V
F
R
N
Q
L
K
A
-----