@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VP70: (2017-11-20 )
MNKNRYRVIFSQARGMFIAVAEIVKSRTKMAGQSIAAGNETVTNSLTPNSYKKLNPLHFSVVTLLGAVVYTIPLSSIANTQIHADKSAPSNQQAQILNSANGTVQVNIQTPSAGGVSRNTYSQFDVGQQGAILNNSRNNVQTQIGGWVQGNANLARGEAKVILNEVNSSNPSQLRGYLEVAGKSAQVVIANPSGLVCDGCGVINADRFTLTTGQAVMNQGYLESFRVREGQVTIEGKGLNGSLTPYTDIYARALKVNAGLYANELKTVLGQNDISIQDPSAPQIAKATTGTNTTPQPDFALDVGQLGGMYAGKIYLVGTEQGLGVRNAGSMNATTGQLSLNANGDLINTGNMIANKDQIAIQAQNIKNSGNISSTQHNIQIKADNIQNSGLIATNDEIQLNTQDKIDNNDGVINAGRIDFTAQTLSNDKGKIEQTGQQQLNISAKTLDNTQGLIGQATKESSGTSGGTTTPSVTDPEQQSSAQDSSTVEVAPVDLTPKTFQTGNIQIAQGIDNVAGQIVNNADINLKVQDSIKNNAGEIQLPELQFSGQNFENQQGKFTAKVVNINAQNIDNQKGVMSASQSFDLTAQQLNNNQGRLQSTKALNITATEIDNRQGQILAADALTLNSSNTNNTQGVIASVNADAQLNIKSLDNSKGEISAQNVHLTGQSLKNQQGTIQAKTADLNINVDQINNGSTKDLAGNLIAAQNLKLNAQQLQSTGQIYAGDTADLTVEQLKQHGQLAALNAVRVQSKDIESDQNAIWVAGLDQEGKLSNTTSELNIDAQNAQIAGKILSGDQINIKAAQTTDLSQSESQAKNVQIETTQFDTSSAKIIADRQLDIRALQSINNEKGQYSAEQVNLNTAQLNNNQGLIQHTGKNDFILNVADRIANHAGKIISNAKTTEIKTNTLSSVAGEILHAGDQHLKITAQNLQGQQGKIQSNSDLQLNLGTANLDKALTAAQSINLTATELSHQQGQLIQNDANGHLQVNVVQTLNNMSGVISAAGNADIKTADLNNQSGVIQTLANKDLSIESQKLENQSGKIVAGRDAAIKTTQLNNDTGTVYAAGKLGLHATQDVSNQQGLIAAKQSLNIEAQNLNNSKGQIQTESGDANLTIAQILNNQAGHIQAANALNIVATQVENQAGQLLSGTDTQLDVAHLNNQSGTIYSKKQLDLNVSGSTDNSAGTLAADQNLNLNTQNLLNQAGQIRSENADLKLNIAQDVQNNTGLISAAKNLNLTAKNITSQQGKVQSGANANIQLNNFDNTEGVVYAEEQLQLSATGKLNNTQGIVAAEQSTDIRAGSVINDAGQIRSQQDQLKLNVQQDISNQNGEISAAKSIELNAQKVSNQKGKVIAGESLNVTAQQVDSIEGTIYAKEQLHLTVADQFNNQSGTIAANQLVQIQAKNLNNTAGKIRSEQNQLDLNVEQNLDNQTGQIYAGSQANIHTTELNNQQGTIYSQNQLDLNASQLNNQQGQIYSGGQEQLKVQGDIQNQKGVLAAGQNLNINSAGLDNTAGTIRSENADITLNAQGQLINAQGDIYAGHNASLNSVGLDNSSGQIAAQNQLTIDTQKQQLSNQNAKIIARAVDLKTGKLDNQTGLIQAEQSVKIDTQQNALLNNNSGNNAGILSQGGLDIANVSQLENSNGYIAAIGSANLTAQNINNNSGQINSQADLTIQQQLAGGRIDNVAGQIQAQKNISLNADTINNAGTVSHIIAGEKLTANASKVMNEQTKDSNLLGGLHAKNIEINAGELDNQSGVIRASENATLNINNQLSNQLGSITSLNRLNIGTANKILNLNNTDGELLAKNQLNLKANELVNKGKIISEGNVDIDLMQSYSHTQADQIAANGTLKLSTEQDLINQSELSAGQKVELNAKNIQNQTGASISSNQTHLIAQDTIHNQGLINGELTHIQANRVWNDGARIYGTQVAIQSNTLDNKSNANGTGAVIASRGDMDLGIQILNNQSGGVVKENGRDNAWIFSAGQLNVGGSLNEELQAQGNADKIYNGSAVIESLGDMYLGANNIQNTNENLVIALIEKYRKQVHEYGKDGEVWDSSVIRLGSSSRGLSNAILYVPQEEGGAPTREIGEDWSYYEYTQIHSEDEVQSTSPAQIIAGGNLSFTPDADFVNKDSQVLVGLQITNGIGSISNQSTALRSVDQTAPGGFSQWHSVGWNTKGTEHRHRWGSKVNYQPADIINTMPISLGIVKEYTSQQSSNPVENLNSTNVQTEIAQAQSVDLTALSTQKLNNQQLDLNAGQSIAEIGKNIQQPDLPDQIGVEANPTTDIQAEQNNIDRVEGEELNQVNNTASAVDSATDITVRTVSQDFLNLPSNALFITTKDSQAQYLVETDPAYANYRNWLSSDYMIKALGLDPAMQQKRIGDGYYEQRLVQDQVAKLTGYRFLEGYGSDEEQYKALMNNGLSFAKQYKLRPGIALTETQIAQLTSDIVWLEEKTVKLADGTTTQALVPQIYVKARVGDLKGDGTLISADSIQLDVQGDVFNSGTIAGRQAVVLNAENVEILNGRIQANQVGLNTSKDLNIIGGQIQAEQAVDLNVGRNFNLESSTQHSENKIGESTFTYTGLDRVAGVYTKAPTAIKSSDTENLKTSISIRVGGDSDLKAAQIQNANGSTQILTQGNLNIGAIQTGISNKGYANEKNYNYSITQIDQGSSIQSQGTANLSANKIQGKAVDIASQQGDIVLNAQQGISLENGKNLHSTDSAMSAQSSGMLGRNTERNEVWKSDQSIANNLKAGGNIVLNTSQGDITATHLKANAGETIQVQAKNGHVTLNSALNETSQSTTSSSTNFATYNNRQSGYIDQEVAQTQLVAGKNVDINAAKNIELQANDVQAGNSIYVGNTLMQRQVDGTLKAADGSVMPENVKLSTLETHDQQWDEQQKGYRGVVKELMKVTEVGLAGVQSLFPGVKVDTKLTIGESNSKREEQIKQTGTNLTANDVYVGSSGQTTLTSSDITAKNTILSGQKVTLNAAEEQNISATSHSKETIEGLGVKLNKDSVRLGGFVSEDTTQSTKTTETTHKAGSIQTENLKIQGAEGVDILGQNIKATGDTVLDHGRGDLNIGGYENKTTVEDKTHKETISTEVGVRNAYLDAALAVGAVKDAAEVVKQAKDQYSQAQRDYASGKITKEALDDTKANVAMATANLANAQIAVGSAAATAAASSATYGFTIGANGERIETTTTTNTTQGKWQGSQLDLNNLTLKSENQDVNLQGSRLTATGTTTFDGTKDFNISAGKEHGQQETSSKTNNQSVSYTYGGGGSASVGKQTSKSHAESLTHVNSEVALNRTEGQLNKLNIQGGEVSIADRGNLQVNQIHVESLQDTASGNSSSKGGSVGVGIGSGGLSNVTASYNQAKGQNDKAWVNETSKLLIGNAQNDADLDAMGVQKVSNIGGVIANSTKNSDASLTDHGKLNYTGALELKDLQDHSSESNRGFNVSTSVGTSIKGESKESSFHPSGSTTVGLQSTGNEQEQLTKATMGQGTLKNSTALSNRDINNTQEITRDQATGLLNGSVTVDNRLLTESGRQQIIQEQKDLPQNAEIIGKMTAAGVTSLGVATASLASGDQNLKQAYDTVMNPARTFDFVQKHPEAATVLEQFKNGNYDRLLATKGSIQLLAQALGQDVNVLTTSITSFLNIKGAYDHQTDTVVLDVNNENRSSILNTTGHEIAHGQGIKNETSADLVGKSVDWAFNSGVKNNQVTIDQYKGQLGDGKDASTQAQNIAELVKDNTTIVDAISDHGDKIDEKTSVWQDIKYLGCWNDECVAAYKQMDAAQEKAYRLGQAKATTKFVNDIKNLPNVPKEVYEALTKDPMGTMSAIWEGVKNIPGELWDTGKTITKGNLVGKSPAEFEKMGNAEMTTALNGLSAAISAGTVTVAKKGGGIVIEAAKSAKRILQNDPAKLPTITTSAGGYIKASLITENGKIIDPPKDVLNKQKQLLGNKDKNVTGVLREEIADSYFKNSGYTKLESKCGSNCFDGVYMKNGELYVVEVKPLSRNAINLSSNKNSPNDIGVQMSDKWIDSRITALKESNNVDSMKTATILQKARLDKKPINKIVVGVNDSRAITLNLGQVGSK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100....-..-.110....-...120.......130-.......140..-.....150.......160.......170.......180.......190......-.200.......210-----.......220......------.--230-........240.......250.......260.------.------.....270....------.-..280.......290..-.....300.......310......--.320.......330.......340.......350.......360...-....370.......380..-----------------...--..390.......400.....---..410.......420.......430.......440.......450.......460.......470.......480.......490.......500........510.......520.......530.......540.....--...550.......560.......570.......580.......590.......600-.........610.......620.......630.......640.......650.......660.......670.......680.......690.--......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......--880.....---..890.......-900.......910.--......920......---.930.......940.......950.......960.......970.......980.......990.......1000......1010--........1020......1030-........1040......1050..-....1060......1070......1080-......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......1970......1980......1990......2000......2010......2020......2030......2040......2050......2060......2070......2080......2090......2100......2110......2120......2130......2140......2150......2160......2170......2180......2190......2200......2210......2220......2230......2240......2250......2260......2270......2280......2290......2300......2310......2320......2330......2340......2350......2360......2370......2380......2390......2400......2410......2420......2430......2440......2450......2460......2470......2480......2490......2500......2510......2520......2530......2540......2550......2560......2570......2580......2590......2600......2610......2620......2630......2640......2650......2660......2670......2680......2690......2700......2710......2720......2730......2740--------......-2750......2760......2770-.........2780......2790......2800....--..2810......2820---......2830......2840......2850......2860......2870......2880......2890......2900.....-------.2910...--...2920------------........2930......2940......2950......2960......2970......2980......2990......3000......3010......3020......3030......3040.....-------.3050......3060......3070......3080......3090.--.....3100........3110..-----------....3120....--..3130......3140......3150......3160......3170......3180....-..3190......3200.-.....3210......3220......3230......3240......3250......3260......3270......3280-......3290......3300......3310....------..3320......3330......3340......3350......3360......3370......3380......3390......3400......3410......3420......3430......3440......3450......3460......3470......3480......3490......3500......3510......3520......3530......3540......3550......3560......3570......3580......3590......3600......3610......3620......3630......3640......3650......3660......3670......3680......3690......3700......3710......3720......3730......3740......3750......3760......3770......3780......3790......3800......3810......3820......3830......3840......3850......3860......3870......3880......3890......3900......3910......3920......3930......3940......3950......3960......3970......3980......3990......4000......4010......4020......4030......4040......4050......4060......4070......4080...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNKN
R
Y
R
V
I
FSQAR
G
M
F
I
A
V
A
E
I
V
K
S
R
T
K
MAGQSIAAGNETVTNSLTPNSYKKLN
P
L
H
F
S
V
V
T
L
L
G
A
V
V
Y
T
I
PLSSIAN
T
Q
I
H
ADKSAPSN
Q
Q
A
Q
I
LNSAN
G
T
V
Q
V
-
N
I
-QTPSAGGV-SRNTYSQFDVGQQ
G
A
I
-LNNSRNN
V
Q
T
QI-G
G
W
VQGNANLARG
E
A
K
V
I
L
NEVNSS
N
P
S
Q
L
R
G
Y
L
E
VAGKS
A
Q
V
V
I
ANPS
G
L
V
CD-GCGVINAD
R
F
T
LTT-----
G
Q
A
V
M
N
Q
G
Y
L
E
S
F
R
VR------E--
G
Q
--
V
T
I
E
GKGLNGSLT
P
Y
T
D
I
Y
A
R
A
L
KVNA
G
L
Y
A
N
------
E
------
L
K
T
V
LGQNDISI------Q-DPSAP
Q
I
A
KATTGTNTT-PQPD
F
A
L
D
V
G
QLGGMYA
G
K
I
Y
L
V
G--TEQGLGVRNAGSMNAT
T
G
Q
L
S
LNANG
D
L
INTGNMIANK
D
Q
I
A
I
Q
AQN-IKNSGNISST
Q
H
N
I
Q
I
K
AD-----------------NIQ--NS
G
L
I
ATN
D
E
I
Q
L
NTQDKID---NND
G
V
I
N
AG
R
I
D
F
T
A
Q
T
LSNDKG
K
I
E
QTGQ
Q
Q
L
N
I
S
A
KTLDNTQ
G
L
IGQATKESSGTSGGTTTPSVT
D
P
E
Q
QSSAQDSS
T
V
E
V
A
PVDLTPKTFQ-TG
N
I
Q
I
A
Q
G
I
D
N
V
A
G
Q
IVNNA
D
I
N
L
K
V
Q
D
SIKNNAGEIQ-LP
E
L
Q
F--SGQNFENQQG
K
F
T
A
K
V
V
N
I
NAQNIDNQKG
V
M
SASQSF
D
L
T
A
Q
Q
LNNNQGR
L
Q
S
T
---
K
A
L
N
I
T
A
T
EIDNRQ
G
Q
I
L
A
A
D
A
L
T
LNSSNTNNT
Q
G
V
I
A
SVNA
D
A
Q
L
N
I
K
SLDNSKGE
I
S
A
Q
N
V
H
L
TGQSLKNQQ
G
T
I
Q
A
K
T
A
D
L
N
I
N
V
D
QINN--GS
T
K
D
LAG
N
L
I
A
AQNLKL
N
A
Q
Q
L
Q
STG
Q
I
YAGDTAD
L
T
V
E
Q
L
K
QHGQ
L
A
A
L
N
A
V
R
V
QSKDIESDQ
N
A
I
W
V
AGLDQEGKLSNTT
S
E
L
N
IDAQN
A
Q
I
A
G
K
ILSG
D
Q
I
N
I
K
AAQTTDLSQSESQAK
N
V
Q
I
E
T
T
QFDTSS
A
K
I
I
ADRQ
L
D
I
R
A
L
Q
S
INNEKGQYSA
E
Q
V
N
L
N
T
A
Q
LNNNQ
G
L
I
Q
HTGKN
D
--
F
I
L
N
V
A
D
R
---
I
A
N
H
A
G
K
I
ISNA-KT
T
E
I
KT
N
T
L
S
S
V
A
--
G
E
I
L
HAGD
Q
H
L
K
I
T
A
---QNLQGQQGKIQSNS
D
L
Q
L
N
LGTA
N
L
D
K
A
L
T
A
A
QSI
N
L
T
A
T
ELSHQQGQLIQNDANG
H
L
Q
V
N
V
V
Q
T
LNN
M
S
G
V
I
SAAGNA
D
I
K
T
----ADLNNQ
S
G
V
I
Q
T
L
ANKDLSI---
E
S
Q
K
LENQSG
K
I
V
AGRD
A
A
I
K
T
T
Q
-LNNDT
G
T
V
Y
A
AGKLG
L
H
ATQDVSNQQG
L
-
I
A
AKQSL
N
I
E
A
QNLNNSK
G
Q
I
Q
TESGDA
N
L
T
I
A
Q
I
LNNQAG
H
I
Q
AAN
A
L
N
I
V
A
T
Q
V
E
NQAGQLLSGTDT
Q
L
D
V
A
H
LNNQS
G
T
I
Y
S
K
K
Q
L
D
L
N
VSGSTDNSAG
T
L
AADQNLNL
N
T
Q
N
L
L
N
Q
AGQIRSENA
D
L
K
L
N
I
A
Q
DVQNNTG
L
I
S
AAKN
L
N
L
T
AKNITSQQGKVQSGANA
N
I
Q
LNNFDNTE
G
V
V
Y
A
E
E
Q
L
Q
L
S
ATGKLNNTQ
G
I
V
A
AEQSTDIRAGSVIN
D
A
G
Q
IRSQ
Q
D
Q
L
K
L
N
V
Q
Q
DISNQNG
E
I
S
A
A
K
S
I
E
L
N
A
Q
KVSNQKG
K
V
I
AGESL
N
V
T
A
Q
Q
V
DSIE
G
T
I
Y
A
K
E
Q
L
H
L
T
V
A
D
QFNNQSG
T
I
A
A
N
Q
L
V
Q
I
Q
AKNLNNTAGKIRSEQN
Q
L
D
L
NVEQNLDNQT
G
Q
I
Y
AGSQA
N
I
H
T
T
ELNNQQ
G
T
I
Y
SQNQLDL
N
A
S
QLNNQQG
Q
I
YSG
G
Q
E
Q
L
K
V
QGDIQNQK
G
V
L
AAGQNLNINSAGLDNTAGTIRSENA
D
I
T
L
NAQG
Q
L
I
NAQG
D
I
YAGHNASLNSVGLDNSSG
Q
I
A
AQ
N
Q
L
T
I
D
T
Q
K
Q
Q
LSNQN
A
K
I
I
A
R
A
V
D
LKTGKLDNQT
G
L
I
Q
AE
Q
S
V
K
I
DTQQ
N
A
L
LNNNSGNNA
G
I
LSQGGLDI
A
N
V
S
Q
LENSN
G
Y
I
A
A
IGSA
N
L
T
A
Q
NINNNSGQINSQA
D
L
T
I
Q
Q
Q
LAGGRI
D
N
V
A
G
Q
I
Q
A
QKN
I
S
LNADTINNAGT
V
S
H
IIAGEKLTA
N
A
S
K
V
M
N
EQTKDSNLLG
G
L
H
A
K
N
I
E
I
NAGELDNQS
G
V
I
R
ASEN
A
T
L
N
I
N
N
Q
L
S
N
Q
LGSITSL
N
R
LNIGTA
N
K
I
L
N
LNNTDG
E
L
L
A
KNQLN
L
K
A
N
E
LVNKG
K
I
ISEGNV
D
I
D
L
M
Q
SYSHTQ
A
D
QIAAN
G
T
L
K
LS
T
E
Q
D
LI
N
Q
S
ELSAG
Q
K
V
E
L
NAKNIQNQTGASISSNQ
T
H
L
I
A
QDTIHNQGLING
E
L
T
H
I
Q
ANRVWNDG
A
R
I
Y
G
T
Q
V
A
I
Q
SNTLDNKSNANG
T
G
A
V
I
ASRGD
M
D
L
G
I
Q
I
L
NNQSG
G
V
V
KENGRD
N
A
W
I
F
SAG
Q
L
NVGGSL
N
E
E
L
QAQGNADKIYN
G
S
A
V
I
E
S
L
G
D
M
YLGANNIQNTNE
N
L
V
I
A
L
I
E
K
Y
R
K
Q
V
H
EYGKDGEV
W
D
S
S
V
I
RLGSSSRGLS
N
A
I
L
Y
V
PQEEGGA
P
T
R
E
IGEDWS
Y
Y
E
Y
T
QIHSEDEVQSTSP
A
Q
I
I
AGGNLSFTPDADFVNKDS
Q
V
L
V
G
L
Q
I
TNGIGSISN
Q
S
T
A
L
R
S
V
DQTAPGG
F
S
Q
W
HSVGWNTKG
T
E
H
R
H
RWGSKVNYQ
P
A
D
I
INTMPI
S
L
G
I
V
K
E
Y
T
SQQSSNPVENLNSTN
V
Q
T
E
IAQAQSV
D
L
T
A
L
S
TQKLNNQQLDLNAG
Q
S
I
A
E
I
G
K
NIQQPDLPDQIGVEANPTT
D
I
Q
AEQNNIDRVE
G
E
E
L
N
QVNN
T
A
SAVDSAT
D
I
T
V
R
T
V
S
Q
D
F
LNLPS
N
A
L
F
I
T
TKDSQ
A
Q
Y
L
V
ETDP
A
Y
A
N
Y
R
N
WLSSD
Y
M
I
K
ALGL
D
P
A
M
Q
Q
KRIG
D
G
Y
Y
E
Q
R
L
V
Q
D
Q
V
A
K
L
TGY
R
F
L
EGYGS
D
E
E
Q
Y
K
A
L
M
NN
G
L
S
F
A
K
Q
YKLRPGIA
L
T
E
T
Q
I
A
Q
L
T
S
D
I
V
W
L
EE
K
T
V
K
LADGTTT
Q
A
L
V
P
Q
I
Y
V
K
A
R
VGDLKGD
G
T
L
I
SA
D
S
I
Q
L
D
VQGDVFNSGTIAG
R
Q
A
V
V
L
NAE
N
V
E
I
LN
G
R
I
Q
A
N
QVGLNTSKDLNIIG
G
Q
I
Q
A
E
Q
A
V
D
LNVGRNFNLESSTQHSENKIGES
T
F
T
YT
G
L
D
R
V
A
G
V
YTKAPTAIKSSDTEN
L
K
T
S
I
S
I
R
VGGDSD
L
K
A
A
Q
I
QNANGS
T
Q
I
L
TQGN
L
N
I
G
A
I
QTGISNKGYANEKNYN
Y
S
I
T
Q
IDQGSSIQSQGTANLSANKIQ
G
K
A
V
D
IASQQG
D
I
V
L
NAQQGISLENGKNLHSTDSAM
S
A
QSSGMLGRNT
E
R
N
E
V
WKS
D
Q
S
I
--------
A
N
NLKA-G
G
N
I
V
L
NTSQG
D
I
T
A
T
H
L
KAN----AG
E
T
I
Q
V
Q
AKN
G
H
V
T
L
N
S
ALNETSQSTTSSST
N
F
A
T
Y--NNRQSGY
I
D
Q
E
V
A
Q
T
Q
---
L
VAGKN
V
D
I
N
AA
K
N
I
E
L
Q
ANDVQAG
N
S
I
Y
VG
N
T
L
M
Q
R
QVD
G
T
L
KAADGSVMPEN
V
K
L
S
T
LET
H
D
Q
Q
W
D
E
Q
QK
G
Y
R
G
V
V
K
E
L
M
K
V
T
-------
E
V
G
L
A
G
V
Q
--
S
LFPG--------------V
K
V
D
T
K
L
T
IGESN
S
K
R
E
E
Q
I
K
Q
TGTNLTAN
D
V
Y
VGSSG
Q
T
T
L
TSSDITAKNTILSG
Q
K
V
T
L
NAAEEQNISATSH
S
K
E
T
I
E
GLG
V
K
LNKD
S
V
R
LG
G
F
VSEDTTQSTKTTETTHKAGS
I
Q
TE
N
L
K
I
QGA-------E
G
V
D
I
LGQNIKATGD
T
V
LDHGRGDLNIGGYENKTTVEDKTHKETIS--TEVGV
R
N
--
A
Y
L
D
A
A
L
A
VG
A
V
K
D
-----------
A
A
E
V
V
K
Q
A
K
D
Q
Y
--
S
Q
A
Q
R
D
YASGK
I
T
K
E
A
LDDTKA
N
V
A
M
A
TANLAN
A
Q
I
A
VGSAAATAAASS
A
T
Y
G
F
T
IGANG-
E
R
I
E
T
T
TTTNTTQGKWQ-GSQLDLN
N
L
T
LKSENQ
D
V
N
LQG
S
R
L
T
ATGTTTFDGTKDFNISAGKEHGQQETSSKTNN
Q
S
V
S
Y
T
YGGGGSASVGKQ
T
S
K
-
S
H
A
E
S
L
T
HVNS
E
V
A
L
NRTEGQL
N
K
L
N
IQGG
E
V
S
I
------ADRG
N
L
Q
V
N
Q
I
H
V
E
S
L
Q
D
TASGNSSSKGG
S
V
G
V
G
IGSGGLSNVTASYNQAKGQND
K
A
W
V
NETS
K
L
L
I
GNAQNDA
D
L
D
A
M
G
V
Q
K
V
S
NIG
G
V
IANSTKNSDASLTDHG
K
L
N
YT
G
A
L
E
L
K
D
L
QDHSSESNRG
F
N
V
STSVGTSIKGESKESSFHPSG
S
T
T
V
G
LQSTG
N
E
Q
E
Q
L
T
K
A
TMGQGTLKNSTALSNRDIN
N
T
Q
E
I
T
R
D
Q
ATGLLNG
S
V
T
VDNRLL
T
E
S
G
R
Q
Q
I
I
Q
E
Q
KDLP
Q
N
A
E
I
I
G
K
M
T
AAGV
T
S
LG
V
A
T
A
SLASG
D
Q
N
L
K
Q
A
Y
D
T
VMN
P
A
R
T
F
D
F
V
Q
KHP
E
A
A
T
V
L
E
Q
F
KNGNY
D
R
L
LATK
G
S
I
Q
L
L
A
Q
A
LGQD
V
N
V
L
T
T
S
I
T
S
F
L
N
I
K
G
AYDHQT
D
T
V
V
L
D
VNNEN
R
S
S
I
LNTTGHEIAHGQGIKNET
S
A
D
LVGKSV
D
W
A
FNSGVKNN
Q
V
T
I
D
Q
YKGQLGDGKDA
S
T
Q
A
Q
N
I
A
E
L
VKDN
T
T
I
V
D
A
I
SDHGDKI
D
E
K
T
S
V
W
Q
D
I
K
Y
LGCW
N
D
E
C
V
A
A
Y
K
Q
M
D
A
A
Q
E
K
A
Y
RLGQA
K
A
T
T
K
F
V
N
D
I
K
NLPNV
P
K
E
V
Y
E
A
LTKDPM
G
T
M
S
A
I
W
E
G
V
K
NI
P
G
E
LWDTGKTITKGNLVGKS
P
A
E
F
E
KMGN
A
E
M
T
T
A
L
N
G
L
S
A
A
ISA
G
T
V
T
V
A
KKG
G
G
I
V
I
E
A
A
K
S
A
K
R
I
L
QNDPAKL
P
T
I
TTSAG
G
Y
I
K
A
S
L
I
TEN
G
K
IID
P
P
K
D
V
L
N
K
Q
K
Q
L
LGNKDK
N
V
T
G
V
L
R
E
E
I
A
D
S
Y
F
KNSGY
T
K
L
E
S
KCGSNCFD
G
V
Y
M
KNG
E
L
Y
V
V
E
V
KPLSRN
A
I
NLSSNKNSPNDI
G
V
Q
M
S
D
K
W
I
D
S
R
I
T
A
LKESNNVD
S
M
K
T
A
T
I
L
Q
K
ARLDKKPI
N
K
I
V
V
GVNDS
R
A
I
T
L
NLGQVGSK
31
Fugue
72.00
31%
-
* C5 *
-
1RWR
-
FHAB_BORPE
A:
[1-297]
-------------------------------------------------------------------------------------
Q
G
L
V
P
Q
G
Q
T
Q
V
L
Q
G
G
N
K
V
P
V
V
-
N
I
-
A
D
P
N
S
G
G
V
-
S
H
N
K
F
Q
Q
F
N
V
A
N
P
G
V
V
-
F
N
N
G
L
T
D
G
V
S
R
I
-
G
G
A
L
T
K
N
P
N
L
-
T
R
Q
A
S
A
I
L
A
E
V
T
D
T
S
P
S
R
L
A
G
T
L
E
V
Y
G
K
G
A
D
L
I
I
A
N
P
N
G
I
S
V
N
-
G
L
S
T
L
N
A
S
N
L
T
L
T
T
-----
G
R
P
S
V
N
-
G
G
R
I
G
L
D
V
Q
------
Q
--
G
T
--
V
T
I
E
R
G
G
V
N
A
T
G
L
G
Y
F
D
V
V
A
R
L
V
K
L
Q
G
A
V
S
S
K
------
Q
G
K
P
L
A
D
I
A
V
V
A
G
A
N
R
Y
D
H
------
A
-
T
R
---
R
A
T
P
I
A
A
G
A
R
G
A
-
A
A
G
A
Y
A
I
D
G
T
A
A
G
A
M
Y
G
K
H
I
T
L
V
S
--
S
D
S
G
L
G
V
R
Q
L
G
S
L
S
S
P
-
S
A
I
T
V
S
S
Q
G
E
-
I
A
L
G
D
A
T
V
Q
R
G
P
L
S
L
K
G
A
G
-
V
V
S
A
G
K
L
A
S
G
G
G
A
V
N
V
A
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
68.67
33%
-
- C5 -
-
1RWR
-
FHAB_BORPE
A:
[7-296]
-------------------------------------------------------------------------------------------
G
Q
T
Q
V
L
Q
G
G
N
K
V
P
V
V
-
N
I
-
A
D
P
N
S
G
G
V
-
S
H
N
K
F
Q
Q
F
N
V
A
N
P
G
V
V
-
F
N
N
G
L
T
D
G
V
S
R
I
-
G
G
A
L
T
K
N
P
N
L
T
R
-
Q
A
S
A
I
L
A
E
V
T
D
T
S
P
S
R
L
A
G
T
L
E
V
Y
G
K
G
A
D
L
I
I
A
N
P
N
G
I
S
V
N
-
G
L
S
T
L
N
A
S
N
L
T
L
T
T
-----
G
R
P
S
V
N
G
G
R
I
-
G
L
D
V
Q
------
Q
--
G
T
--
V
T
I
E
R
G
G
V
N
A
T
G
L
G
Y
F
D
V
V
A
R
L
V
K
L
Q
G
A
V
S
S
K
QG
K
P
L
A
D
------
I
A
V
V
A
G
A
N
R
Y
D
H
------
A
-
T
R
R
A
T
P
I
A
A
G
---
A
R
G
A
-
A
A
G
A
Y
A
I
D
G
T
A
A
G
A
M
Y
G
K
H
I
T
L
V
S
--
S
D
S
G
L
G
V
R
Q
L
G
S
L
S
S
P
-
S
A
I
T
V
S
S
Q
G
E
I
A
L
G
D
A
T
V
Q
R
G
P
-
L
S
L
K
G
A
G
-
V
V
S
A
G
K
L
A
S
G
G
G
A
V
N
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
68.05
32%
-
- C5 -
-
1RWR
-
FHAB_BORPE
A:
[8-288]
--------------------------------------------------------------------------------------------
Q
T
Q
V
L
Q
G
G
N
K
V
P
V
V
-
N
I
-
A
D
P
N
S
G
G
V
-
S
H
N
K
F
Q
Q
F
N
V
A
N
P
G
V
V
-
F
N
N
G
L
T
D
G
V
S
R
I
-
G
G
A
L
T
K
N
P
N
L
T
R
-
Q
A
S
A
I
L
A
E
V
T
D
T
S
P
S
R
L
A
G
T
L
E
V
Y
G
K
G
A
D
L
I
I
A
N
P
N
G
I
S
V
N
-
G
L
S
T
L
N
A
S
N
L
T
L
T
T
-----
G
R
P
S
V
N
G
G
R
I
-
G
L
D
V
Q
------
Q
--
G
T
--
V
T
I
E
R
G
G
V
N
A
T
G
L
G
Y
F
D
V
V
A
R
L
V
K
L
Q
G
A
V
S
S
K
------
Q
------
G
K
P
L
A
---
D
I
A
V
V
A
G
ANR
Y
-
D
H
A
T
R
R
A
T
P
I
A
A
G
A
R
G
A
-
A
A
G
A
Y
A
I
D
G
T
A
A
G
A
M
Y
G
K
H
I
T
L
V
S
--
S
D
S
G
L
G
V
R
Q
L
G
S
L
S
S
P
S
-
A
I
T
V
S
S
Q
G
E
-
I
A
L
G
D
A
T
V
Q
R
G
P
L
S
L
K
G
A
G
-
V
V
S
A
G
K
L
A
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
64.36
36%
-21
- C5 -
-
5KEH
-
HLYA_PROMI
A:
[2-238]
--------------------------------------------------------------------------------
G
I
V
P
D
A
G
---
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
-
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
A
E
V
F
G
I
A
A
E
A
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
NT
N
L
--
L
S
L
G
K
N
G
L
N
T
--
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
-
F
D
I
L
-----------
S
S
-
Q
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
A
G
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
61.93
21%
75
- C4 -
-
4RM6
-
HXUA1_HAEIN
A:
[2-817]
------------------------------------------------------------------------------------
A
R
D
L
P
Q
G
S
S
V
V
V
G
E
A
N
V
S
T
I
G
N
-
K
M
-
T
I
D
Q
K
T
P
T
-
T
Q
I
D
W
H
S
F
D
I
G
Q
N
---------
K
E
V
E
F
K
------
Q
P
D
A
N
------
S
V
A
Y
N
R
V
T
G
G
N
A
S
Q
I
Q
G
K
L
T
A
N
G
---
K
V
Y
L
A
N
P
N
G
V
I
I
T
Q
G
A
E
I
N
V
A
G
L
F
A
T
T
K
-----
D
L
E
R
I
S
E
N
N
K
F
T
R
K
L
K
------
D
--
G
Q
--
V
V
K
E
G
Q
V
I
N
K
G
-----
K
I
K
A
K
D
F
V
V
L
N
G
------------------
D
K
V
I
N
E
G
E
I
D
A
------
T
-
N
N
G
---
K
V
Y
L
S
S
G
Y
N
F
T
F
T
L
S
D
S
S
I
S
V
A
-----------
L
E
D
--
N
A
V
Q
S
I
V
Q
N
E
G
I
I
K
A
--
G
D
I
T
L
N
A
K
G
R
N
Q
A
L
D
S
L
V
M
N
N
G
V
L
E
A
T
---------
K
V
S
N
K
N
G
K
V
V
L
S
A
D
-----------------
D
V
Q
L
N
N
K
S
D
I
K
G
E
S
E
V
V
F
T
N
E
N
K
I
K
I
T
S
Q
T
G
S
K
V
T
S
P
K
I
N
F
T
G
K
S
V
N
I
N
G
D
F
G
R
D
D
S
K
A
H
Y
N
E
E
H
K
R
L
D
-
T
E
V
N
I
D
V
P
D
N
E
N
I
R
I
A
E
K
D
N
T
D
S
F
I
Q
----
T
G
A
L
S
S
L
L
A
N
N
G
K
V
N
L
K
G
K
D
V
N
I
S
G
R
I
H
I
----
D
S
F
R
G
---
S
D
S
L
L
K
L
T
N
Q
G
H
I
K
I
N
H
A
D
I
H
S
T
G
R
L
F
F
I
T
S
L
Q
N
E
K
D
S
Q
S
D
I
T
I
T
D
S
K
I
N
L
G
N
-----
G
A
M
G
L
G
R
S
L
D
--
K
E
N
C
D
N
Q
R
W
C
R
T
E
T
SQR
K
K
F
D
V
H
M
R
N
V
V
F
D
Q
----
V
D
D
V
V
V
A
G
G
F
K
K
V
N
L
D
N
I
V
A
T
G
K
T
N
F
Y
I
D
--------
G
G
V
S
R
N
N
S
R
Y
-------
E
Y
G
V
L
D
L
D
K
R
T
L
L
S
E
L
D
Q
R
R
R
R
W
K
Y
Y
N
D
L
D
L
D
M
N
K
A
Y
W
H
R
F
D
M
R
S
T
I
K
D
T
E
I
N
I
S
N
S
------
K
I
N
L
K
N
G
F
V
H
L
L
A
E
K
I
K
L
D
------
N
S
K
I
D
I
T
F
D
K
D
N
S
-
Q
D
I
S
T
Q
I
N
R
L
G
M
N
G
K
V
S
M
V
---
N
S
H
I
K
I
V
G
D
E
K
S
D
I
S
A
K
A
P
Y
A
T
M
F
L
I
G
E
L
I
G
E
K
S
S
I
F
V
K
S
H
Q
G
Y
T
F
R
T
-
D
G
D
T
K
I
A
G
K
N
S
K
D
D
L
K
I
T
A
I
N
T
G
G
R
------
T
G
K
E
V
--
I
I
N
G
A
P
G
S
---
I
A
N
M
A
F
T
I
G
D
N
A
N
T
K
T
T
I
E
N
A
D
I
T
A
L
A
PN
G
G
T
A
Y
L
S
S
K
G
V
E
I
E
V
N
PN
S
N
F
T
F
F
E
L
P
I
K
G
D
S
T
K
L
S
E
R
G
F
A
R
L
Y
D
K
I
N
G
V
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
59.20
35%
29
- C5 -
-
5KEH
-
HLYA_PROMI
A:
[9-236]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
A
E
V
F
G
I
A
A
E
A
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
A
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.79
35%
38
- C5 -
-
5KDK
-
?
A:
[9-234]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
Y
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
58.02
35%
40
- C5 -
-
5KF3
-
HLYA_PROMI
A:
[9-234]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
A
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
N
L
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
57.99
36%
-
- C- -
-
4W8Q
-
HLYA_PROMI
A:
[31-263]
--------------------------------------------------------------------------------
G
I
V
P
D
A
G
---
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
-
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
Y
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
NT
N
L
--
L
S
L
G
K
N
G
L
N
T
--
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
-
F
D
I
L
-----------
S
S
-
Q
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
56.22
35%
-
- C- -
-
4W8Q
-
HLYA_PROMI
A:
[38-263]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
Y
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.18
35%
34
- C- -
-
3FY3
-
HLYA_PROMI
A:
[38-263]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
Y
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
55.15
35%
37
- C- -
-
4W8T
-
HLYA_PROMI
A:
[38-263]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
S
E
V
F
G
I
A
A
E
Y
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
54.40
35%
36
- C- -
-
4W8S
-
HLYA_PROMI
A:
[38-263]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
S
E
V
F
G
I
A
A
E
S
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
S
A
L
D
S
Y
F
F
G
S
M
Q
S
G
R
I
R
I
I
N
--
T
A
E
G
S
G
V
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
53.96
35%
36
- C5 -
-
5KKD
-
HLYA_PROMI
A:
[9-205]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
Q
E
V
F
G
I
A
A
E
A
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
Q
------
H
F
D
I
L
S
S
Q
-------------
K
P
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.64
37%
34
- C5 -
-
5SZ8
-
HLYA_PROMI
A:
[9-193]
-------------------------------------------------------------------------------------------
H
Q
G
P
D
V
S
A
V
N
G
G
T
Q
V
I
N
I
-
V
T
P
N
N
E
G
I
-
S
H
N
Q
Y
Q
D
F
N
V
G
K
P
G
A
V
-
F
N
N
A
L
E
A
G
Q
S
Q
L
-
A
G
H
L
N
A
N
S
N
L
N
G
Q
A
A
S
L
I
L
N
E
V
V
S
R
N
P
S
F
L
L
G
Q
A
E
V
F
G
I
A
A
E
A
V
L
S
N
P
N
G
I
T
C
D
-
G
C
G
F
I
N
T
S
R
S
S
L
V
V
-----
G
N
P
L
F
E
N
G
Q
L
K
G
Y
S
T
L
------
N
--
N
T
NL
L
S
L
G
K
N
G
L
N
--
T
T
G
L
L
D
L
I
A
P
R
I
D
S
R
G
K
I
T
A
A
------
E
------
I
S
A
F
T
G
Q
N
T
F
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.03
22%
21
- C5 -
-
2ODL
-
?
A:
[94-289]
-----------------------------------------------------------------------------------------------------------------
N
S
V
D
A
-
I
I
N
-
W
K
Q
F
N
I
D
Q
N
E
M
V
Q
F
L
Q
E
---------------------
N
N
N
S
A
V
F
N
R
V
T
S
N
Q
I
S
Q
L
K
G
I
L
D
S
N
---
G
Q
V
F
L
I
N
P
N
G
I
T
I
G
-
K
D
A
I
I
N
T
N
G
F
T
A
S
T
-----
L
D
I
S
N
E
N
I
K
A
R
N
F
T
F
E
Q
T
KDK
A
L
--
A
E
--
I
V
N
H
G
-
L
I
T
V
G
K
D
G
S
V
N
L
I
G
G
K
V
K
N
E
G
V
I
S
V
N
G
G
----
S
------
I
S
L
L
A
G
Q
-
K
I
T
I
------
S
-
D
I
I
N
P
T
I
T
Y
------
S
I
-
A
A
P
--
E
N
E
A
V
N
L
G
D
I
F
A
K
G
G
N
I
N
V
--
R
A
--
A
T
I
R
N
Q
G
K
L
S
A
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
45.11
37%
-140
- C5 -
-
2ODL
-
?
A:
[124-171]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
N
R
V
T
S
N
Q
I
S
Q
L
K
G
I
L
D
S
N
G
---
Q
V
F
L
I
N
P
N
G
I
T
I
G
-
K
D
A
I
I
N
T
N
G
F
T
A
S
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
42.26
16%
61
- C5 -
-
2ODL
-
?
A:
[70-441]
--------------------------------------------------------------------------------------------------------
G
L
-
Q
G
M
D
V
V
H
G
T
A
T
M
Q
V
D
G
N
K
T
I
I
R
N
S
V
D
A
I
-
I
N
W
K
Q
F
N
I
D
Q
N
E
M
V
Q
F
L
Q
E
N
N
N
------
S
A
V
F
N
R
V
T
S
N
Q
I
S
Q
L
K
G
I
L
D
S
N
G
---
Q
V
F
L
I
N
P
N
G
I
T
I
G
-
K
D
A
I
I
N
T
N
G
F
T
A
S
T
L
D
I
S
N
E
N
I
K
A
R
N
F
T
F
E
Q
T
K
D
K
------
A
--
L
A
--
E
I
V
N
H
G
L
I
T
V
G
K
D
G
S
V
N
L
I
G
G
K
V
K
N
E
G
V
I
S
V
N
------
G
------
G
S
I
S
L
L
A
G
Q
K
I
T
------
I
-
S
D
I
-----
I
N
P
T
I
T
Y
S
I
-
A
A
P
E
N
E
A
V
N
L
G
D
I
F
A
K
G
G
N
I
N
V
R
A
A
T
I
R
N
Q
G
K
L
S
A
D
S
V
S
K
D
K
S
G
N
I
V
L
S
A
K
E
G
E
A
E
I
G
G
V
I
S
A
Q
N
Q
Q
A
K
G
G
K
L
M
I
T
G
D
K
V
T
L
K
T
G
A
V
I
D
L
S
G
K
E
G
G
E
T
Y
L
GGDERGEGKN
G
I
Q
--
L
A
K
K
T
S
L
E
K
G
S
T
I
N
V
S
G
K
E
K
---
G
G
R
A
I
V
W
G
D
I
A
L
I
D
G
N
I
N
A
Q
G
S
G
D
I
A
K
T
G
G
-
F
V
E
T
S
G
H
D
L
F
I
K
D
N
A
I
V
D
A
K
E
W
L
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
41.60
16%
55
- C2 -
-
4Q35
13
LPTD_SHIFL
A:
[25-784]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
A
S
Q
C
M
L
G
V
P
S
Y
D
R
P
L
V
Q
G
D
T
N
------
D
L
P
V
T
I
N
A
D
H
A
K
G
D
Y
P
D
D
A
V
F
T
G
S
V
D
I
M
Q
G
N
S
R
L
Q
A
D
E
V
Q
L
H
Q
K
E
-
A
P
G
Q
P
V
R
T
V
D
A
L
G
N
V
H
Y
D
D
N
Q
-------
V
I
L
K
G
P
K
G
W
A
N
L
N
T
K
D
T
N
V
W
E
G
D
Y
Q
M
V
G
R
Q
G
R
G
K
A
D
L
M
K
Q
R
G
E
N
R
Y
T
I
L
D
N
G
S
F
T
S
C
L
P
G
S
D
T
W
S
V
V
G
S
E
I
I
H
D
R
E
E
Q
V
A
E
I
W
N
A
R
F
K
V
G
P
V
P
I
F
Y
S
P
Y
L
Q
L
P
VG
D
K
R
R
S
G
F
L
I
P
N
A
K
Y
T
T
TNY
F
E
F
Y
L
P
Y
Y
W
N
I
A
P
N
M
D
A
T
I
T
P
H
Y
M
H
R
R
---
G
N
I
M
W
E
N
E
F
R
Y
L
S
Q
A
--
G
A
G
L
M
E
L
D
Y
L
P
S
D
K
V
Y
E
D
E
H
P
N
D
D
S
S
R
R
W
L
F
Y
W
N
H
S
G
V
M
DQ
V
W
R
F
N
V
D
Y
T
K
V
S
DP
S
Y
F
N
D
F
DNKYGSSTDG
Y
A
T
Q
K
F
S
V
G
Y
A
V
Q
N
F
N
A
T
V
S
T
K
Q
F
Q
V
F
S
E
Q
N
T
S
S
Y
S
A
E
P
Q
L
D
V
N
Y
Y
Q
N
D
V
G
P
F
D
T
R
I
Y
G
Q
A
V
H
F
V
N
T
R
D
D
M
P
E
A
T
R
V
H
L
E
P
T
I
N
L
P
L
S
N
N
---------------
W
G
S
I
N
T
E
A
K
F
L
A
T
H
Y
Q
Q
T
N
L
D
W
Y
N
S
R
N
T
T
K
L
D
E
S
V
N
R
V
M
P
Q
F
K
V
D
G
K
M
V
F
E
R
D
M
E
M
L
A
P
G
---
Y
T
Q
T
L
E
P
R
A
Q
Y
L
Y
V
P
Y
R
D
Q
S
D
I
Y
N
Y
D
S
S
L
L
Q
S
D
Y
S
G
L
F
R
D
RTYGGLD
R
I
A
S
A
N
Q
V
T
T
G
V
T
S
R
I
Y
D
D
A
A
V
E
R
F
N
I
S
V
G
Q
I
Y
Y
F
T
E
S
R
T
G
D
D
N
I
T
W
E
N
D
D
K
T
G
S
L
V
W
A
G
D
T
Y
W
R
I
S
E
R
W
G
L
R
G
G
I
Q
Y
D
T
R
L
D
N
V
A
T
S
N
S
S
I
E
Y
R
R
D
E
D
R
L
V
Q
L
N
Y
H
Y
A
S
-
P
E
Y
I
Q
A
T
L
P
K
Y
Y
S
T
A
E
Q
Y
K
N
G
I
S
Q
V
G
A
V
A
S
R
P
I
A
D
R
--
W
S
I
V
G
A
Y
Y
Y
D
T
N
A
N
K
Q
A
D
S
M
L
G
V
Q
Y
S
S
C
C
Y
A
I
R
V
G
Y
E
R
K
L
N
G
W
D
N
D
K
Q
H
A
V
Y
D
N
A
I
G
F
N
I
E
L
R
GLSSN
Y
G
L
G
T
Q
E
M
L
R
S
N
I
L
P
Y
Q
N
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
37.64
17%
32
- C1 -
-
5LTE
2
?
A:
[5-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
P
L
E
S
Y
R
E
D
F
S
---
F
R
N
S
P
A
A
I
A
R
F
P
F
P
F
P
E
D
Q
Y
M
Y
S
---
V
N
L
E
P
A
V
S
R
D
P
G
S
V
F
E
H
Q
F
D
V
D
EH
Y
V
S
E
M
A
E
R
A
R
V
L
E
L
D
P
G
R
C
L
V
M
P
-
H
M
A
Q
A
A
W
D
T
L
A
M
L
M
--
E
H
L
A
R
D
Y
P
Q
H
F
R
L
T
R
---
Q
G
D
A
W
H
W
Q
N
L
A
L
G
I
D
Q
R
F
T
F
G
----
D
P
A
S
L
P
C
E
P
L
E
Y
I
T
R
Q
M
Q
G
D
F
A
V
L
D
Q
R
D
G
D
L
F
M
D
A
G
M
V
T
C
P
A
D
W
S
--
L
R
F
D
A
G
M
S
F
K
Q
W
H
SP
V
P
M
A
H
Q
M
G
V
F
D
R
A
L
K
Y
L
L
N
I
QVG
A
P
V
R
R
L
N
W
T
L
T
I
N
P
R
L
D
T
S
P
E
T
Y
H
E
W
G
N
D
R
G
K
V
-
T
P
D
N
V
G
R
L
V
H
L
R
V
E
L
Q
L
M
A
R
L
P
R
S
N
A
L
L
F
G
I
R
T
Y
L
I
S
L
D
E
L
V
S
-----
N
P
A
W
A
Q
R
L
H
R
V
M
R
D
L
P
D
P
I
A
D
Y
K
G
I
T
R
Y
R
Q
T
L
V
D
W
L
R
R
F
D
P
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------