@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VPG2: (2017-11-21 )
MTVSFQEIHPIEIDAQWPQQPFHGFSLDSRKVETGQIFIALTSYSQPEKTRTFAEAALANGALAVISETELGVANEWVCPDVRQRMGEWQKRYLQQADVVKPLRIIAVTGTNGKTTISRLIAELISSQQQRCAVMGTTGNGILPNLTPSTHTTLDALQLQNALHDYAKQGATFASLEASSHGLEQGRLNGCDIEIAVYSNLSRDHLDYHGTLEAYAEAKARLFQFNSLKVAVINLDDAHADLMIKSAQNNPAQPKILTYSLTQNTADYYITDLSYSLAGATFNLVSQQGSFAVESPLLGHFNVENLIAALIAAEQAGFDLQALVNFVPKLIGAPGRMQVIRDDERLFVVDYAHTPDALIQVLKTLKRHVSNQLWAVFGCGGDRDRGKRPLMTQAALDGANPVILTSDNPRTEDPEQIFADMKQGIDFSGHRMHEIHDRREAIKFVAEQAQAGDIVVIAGKGHENYQEINGVRHWFDDVVEVCSAIDAQHHTVDAAYPAQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.----..-.------.--....80.--......----.90........100.......110.......120.......-130-.......140----.-----.......-----------------------150.......160..--.....170.......180.-...-.-.-.190........200.......210........220-..-.....---230....-...240........250.......260.--....-..270.....-..280.......-.-290........300---.......310....------...320.......330.......340----.----------.-...---...350.-.-....-----...360......-.---370.......---380-.---........390.....-.-.400.......410------..------.....420.......430...------....440......----.450.--......460......-.470.......480.......490.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MT
V
S
F
Q
E
I
H
P
I
E
I
DAQWPQQPFHGFSLDS
R
K
VET
G
Q
I
F
I
A
LTSYSQ
P
E
K
T
R
T
F
A
E
A
A
LAN
G
A
L
A
V
I
S
ETE-L----GV-A------N--EWV
C
P
D
V
--
R
Q
R
M
G
E
----
W
Q
K
R
Y
L
Q
Q
A
DVVK
P
L
R
I
I
A
V
TGTN
G
K
T
T
I
S
R
L
I
A
E
L
I
S
S
Q
Q
-
Q
R
C
-
A
V
MGTTGNG-----I-----LPNLTPS-----------------------TH
T
T
L
D
A
L
Q
L
Q
N
A
L
H
--
D
Y
A
KQGA
T
F
A
S
LEASSHGL-EQG-R-L-NG-
C
D
I
E
I
A
V
YSNLSRDHLDYH
G
-
T
L
E
A
Y
A
E
A
K
A
R
L
-
F
Q
-FNS
L
K
---
V
A
V
I
NLD-DAHA-
D
L
M
I
KSAQNNPAQ
P
K
I
L
T
Y
S
LTQ--NTA
D
-
Y
Y
I
TDLSYSL-AG
A
T
-
F
N
L
VSQQ-G-S-FAVESPLLGHF
N
---
V
E
N
L
I
A
A
L
I
A
A
E
QA------GF
D
L
Q
A
L
V
N
F
V
P
K
L
IGAPG
R
M
Q
V
I
R-----D----------D-
E
R
L
---
F
V
V
D--Y-A-H
T
P
D
-----
A
L
I
Q
V
L
K
T
L
K
R
H
-V---SNQ
L
W
A
V
F
GC---G---G---DRDRGKRPL
M
T
Q
AALD-G-AN
P
V
I
L
TSDNPRTE------
D
P
------
E
Q
I
F
A
D
M
K
QGIDFSG
H
R
M
H
E
I
------
H
D
R
R
E
A
I
K
F
V
A
E
Q----AQAG
D
--
I
V
V
I
AGKGHE
N
Y
Q
E
I
-
N
G
V
R
H
W
F
D
D
V
V
E
V
C
S
A
IDAQHHTVDAAYPAQ
1
PsiBlast_PDB
78.55
36%
-21
- C1 -
-
4BUB
1
MURE_THEMA
A:
[27-462]
-----------------------
G
V
S
N
H
S
S
K
V
K
K
G
D
L
F
I
C
--
R
R
-------
E
I
I
P
E
V
M
E
K
G
A
V
A
V
V
V
E
R
E
-
I
----
D
L
-
D
------
F
--
P
Y
I
Q
V
-
F
--
D
S
R
Y
F
E
----
A
K
V
A
S
L
F
F
E
D
P
W
K
D
V
L
T
F
G
V
T
G
T
N
G
K
T
T
T
T
M
M
I
Y
H
M
L
T
S
L
G
-
E
R
G
-
S
V
L
T
T
A
V
K
R
-----
I
-----
L
G
N
S
Y
Y
D
-----------------------
D
I
T
T
P
D
A
I
T
I
L
S
A
M
K
--
E
N
R
E
G
G
G
K
F
F
A
L
E
V
S
S
H
A
L
-
V
Q
Q
-
R
-
V
-
E
G
-
V
R
F
D
V
G
I
F
T
N
I
S
R
D
H
L
D
F
H
G
-
T
F
E
N
Y
L
K
A
K
L
H
L
-
F
D
-
L
--
L
K
DD
G
V
A
V
L
N
---
E
S
L
A
-
D
A
F
N
R
K
S
R
K
-------
I
T
F
G
T
S
K
--
N
-
A
D
-
Y
R
L
G
N
I
E
V
S
W
-
E
G
T
Q
-
F
V
L
E
T
P
D
-
G
-
L
-
L
K
V
F
T
R
A
I
G
D
F
N
---
A
Y
N
A
A
A
A
I
A
A
L
H
Q
L
------
G
Y
D
P
K
D
L
A
S
S
L
E
T
F
T
G
V
E
G
R
F
E
V
V
R
-----
G
----------
A
-
K
K
I
G
L
N
V
V
V
D
--
F
-
A
-
H
S
P
D
-----
A
L
E
K
L
L
K
N
V
R
K
I
-
S
---
Q
G
R
V
I
V
V
F
G
A
---
G
---
G
---
N
S
D
R
G
K
R
P
M
M
S
E
V
A
S
K
-
L
-
A
D
V
V
I
L
T
T
D
D
P
R
G
E
------
D
P
------
E
Q
I
M
E
D
L
I
K
G
I
D
K
R
K
P
Y
L
-
V
L
------
F
D
R
R
E
A
I
E
T
A
L
T
I
----
A
N
R
G
D
--
S
V
V
I
A
G
R
G
H
E
R
Y
Q
I
I
-
D
------------------------------
23
HHSearch
74.15
36%
9
- C1 -
-
4BUB
1
MURE_THEMA
B:
[21-485]
-----------------
Y
D
L
E
I
T
G
V
S
N
H
S
S
K
V
K
K
G
D
L
F
I
C
R
R
G
E
----
D
S
H
E
I
I
P
E
V
M
E
K
G
A
V
A
V
V
V
E
R
E
I
D
----
L
D
-
F
------
P
--
Y
I
Q
V
F
D
S
--
R
Y
F
E
A
K
----
V
--
A
S
L
F
F
E
D
P
W
K
D
V
L
T
F
G
V
T
G
T
N
G
K
T
T
T
T
M
M
I
Y
H
M
L
T
S
L
G
-
E
R
G
-
S
V
L
T
T
A
V
K
R
-----
I
-----
L
G
N
S
Y
Y
D
-----------------------
D
I
T
T
P
D
A
I
T
I
L
S
A
M
K
--
E
N
R
E
G
G
G
K
F
F
A
L
E
V
S
S
H
A
L
-
V
Q
Q
-
R
-
V
-
E
G
-
V
R
F
D
V
G
I
F
T
N
I
S
R
D
H
L
D
F
H
G
-
T
F
E
N
Y
L
K
A
K
L
H
L
-
F
D
-
L
L
K
D
D
G--
V
A
V
L
N
E
S
-
L
A
D
A
---
F
N
R
-------
K
S
R
K
I
T
F
G
T
S
---
K
N
A
D
-
Y
R
L
G
N
I
E
V
S
W
-
E
G
T
Q
-
F
V
L
E
T
P
D
-
G
-
L
-
L
K
V
F
T
R
A
I
G
D
F
N
---
A
Y
N
A
A
A
A
I
A
A
L
H
Q
L
------
G
Y
D
P
K
D
L
A
S
S
L
E
T
F
T
G
V
E
G
R
F
E
V
V
R
-----
G
AKK-------
I
-
G
L
N
---
V
V
V
D
--
F
-
A
-
H
S
P
D
-----
A
L
E
K
L
L
K
N
V
R
K
I
-
S
---
Q
G
R
V
I
V
V
F
G
A
---
G
---
G
---
N
S
D
R
G
K
R
P
M
M
S
E
V
A
S
K
-
L
-
A
D
V
V
I
L
T
T
D
D
P
R
G
E
------
D
P
------
E
Q
I
M
E
D
L
I
K
G
I
D
K
R
-
K
P
Y
L
V
L
------
F
D
R
R
E
A
I
E
T
A
L
T
I
----
A
N
R
G
D
--
S
V
V
I
A
G
R
G
H
E
R
Y
Q
I
I
D
E
E
K
K
V
P
F
Q
D
R
E
V
V
E
E
I
I
R
D
K
L
K
G
--------
28
HHSearch
57.30
22%
-18
- C1 -
-
1GG4
-
B:
[519-942]
----------------
G
A
D
I
T
L
D
A
V
T
T
D
T
R
K
L
T
P
G
C
L
F
V
A
L
K
G
E
R
--
F
D
A
H
D
F
A
D
Q
A
K
A
G
G
A
G
A
L
L
V
S
R
P
-
L
D---
I
D
-
L
------
P
--
Q
L
I
V
K
D
T
--
R
L
A
F
G
E
----
L
--
A
A
W
V
R
Q
Q
V
--
P
A
R
V
V
A
L
T
G
S
S
G
K
T
S
V
K
E
M
T
A
A
I
L
S
Q
C
G
-
N
T
L
-
Y
T
A
G
N
L
N
N
D
-----
I
-----
G
V
----------------------------------
P
M
T
L
L
R
------
L
-
T
P
E
Y
D
Y
A
V
I
E
L
G
A
N
H
Q
G
E
I
A
-
W
T
V
-
S
L
-
T
R
P
E
A
A
L
V
N
N
L
A
---------
S
L
A
G
V
A
K
A
K
G
E
I
-
F
S
-
G
L
P
E
N
G--
I
A
I
M
N
A
D
-
N
N
D
W
-
L
N
W
Q
S
V
I
G
----
S
R
K
V
W
R
F
S
P
N
A
--
A
N
S
D
-
F
T
A
T
N
I
H
V
T
S
-
H
G
T
E
-
F
T
L
Q
T
P
T
-
G
-
S
-
V
D
V
L
L
P
L
P
G
R
H
N
---
I
A
N
A
L
A
A
A
A
L
S
M
S
V
------
G
A
T
L
D
A
I
K
A
G
L
A
N
L
K
A
V
P
G
R
L
F
P
I
Q
-----
L
----------
A
E
N
Q
L
---
L
L
D
D
S-
Y
-
N
-
A
N
V
G
-----
S
M
T
A
A
V
Q
V
L
A
E
M
-
P
----
G
Y
R
V
L
V
V
G
D
MAE
L
---
G
---
A
E
S
E
A
C
H
V
Q
V
G
E
A
A
K
A
-
A
G
I
D
R
V
L
S
V
G
K
Q
S
H
-----------------
A
I
S
T
A
----
S
G
----
V
G
E
H
F
------
A
D
K
T
A
L
I
T
R
L
K
L
L
----
I
A
E
Q
Q
VI
T
I
L
V
K
G
S
R
S
A
A
M
E
E
V
--------------------------------
30
HHSearch
56.51
23%
2
- C1 -
-
4CVM
5
?
A:
[20-446]
----------------
G
E
D
A
V
F
S
A
V
S
T
D
S
R
A
I
G
P
G
E
L
F
I
A
L
S
G
P
R
--
F
D
G
H
D
Y
L
A
E
V
A
A
K
G
A
V
A
A
L
V
E
R
E
-
V
AD--
A
P
-
L
------
P
--
Q
L
L
V
R
D
T
--
R
A
A
L
G
R
----
L
--
G
A
L
N
R
R
K
--
F
T
G
P
L
A
A
M
T
G
S
S
G
K
T
T
V
K
E
M
L
A
S
I
L
R
T
Q
A
G
D
A
E
-
S
V
L
A
T
R
G
N
L
-----
N
-----
N
D
-------------------------------
L
G
V
P
L
T
L
L
Q
------
L
-
A
P
Q
H
R
S
A
V
I
E
L
G
A
S
R
I
G
E
I
A
Y
T
-
V
-
E
L
-
T
R
P
H
V
A
I
I
T
N
A
G
T
A
H
V
---
G
-
G
P
E
K
I
V
E
A
K
G
E
I
-
L
E
-
G
L
A
A
D
G
--
T
A
V
L
N
L
D
-
D
K
A
F
-
D
T
W
K
A
R
A
S
----
G
R
P
L
L
T
F
S
L
D
R
--
P
Q
A
D
-
F
R
A
A
D
L
Q
R
D
A
R
G
C
M
G
-
F
R
L
Q
G
V
A
-
G
-
E
-
A
Q
V
Q
L
N
L
L
G
R
H
N
---
V
A
N
A
L
A
A
A
A
A
A
H
A
L
------
G
V
P
L
D
G
I
V
A
G
L
Q
A
L
Q
P
V
K
G
R
A
V
A
Q
L
-----
T
A---------
S
-
G
L
R
---
V
I
D
D
S-
Y
-
N
-
A
N
P
A
-----
S
M
L
A
A
I
D
I
L
S
G
F
-
S
----
G
R
T
V
L
V
L
G
D
---
M
---
G
-----
A
E
Q
A
H
R
E
V
G
A
Y
A
A
G
-
K
-
V
S
A
L
Y
A
V
G
P
L
M
A
-----------------
H
A
V
Q
A
F
----
G
A
---
T
G
R
H
F
------
A
D
Q
A
S
L
I
G
A
L
A
T
-----
E
D
P
T
T
--
T
I
L
I
K
G
S
R
S
A
A
M
D
K
V
--------------------------------
29
HHSearch
55.73
20%
-26
- C1 -
-
2AM1
2
?
A:
[21-448]
----------------
F
E
D
T
Q
L
E
K
A
E
F
D
S
R
L
I
G
T
G
D
L
F
V
P
L
K
G
A
---
R
D
G
H
D
F
I
E
T
A
F
E
N
G
A
A
V
T
L
S
E
K
E
-
V
----
S
N
-
H
------
P
--
Y
I
L
V
D
D
V
--
L
T
A
F
Q
S
----
L
--
A
S
Y
Y
L
E
K
--
T
T
V
D
V
F
A
V
T
G
S
N
G
K
T
T
T
K
D
M
L
A
H
L
L
S
T
R
Y
-
K
T
Y
-
K
T
Q
G
N
Y
N
N
E
-----
I
-----
G
L
--------------------------------
P
--
Y
T
V
L
H
------
M
-
P
E
G
T
E
K
L
V
L
E
M
G
Q
D
H
L
G
D
I
H
-
L
-
L
-
S
E
L
A
R
P
K
T
A
I
V
T
L
V
G
E
A
H
L
A
F
F
K
-
D
R
S
E
I
A
K
G
K
M
Q
I
-
A
D
-
G
M
A
S
G
---
S
L
L
L
A
P
A
-
D
P
I
V
-
E
D
Y
L
P
I
------
D
K
K
V
V
R
F
G
Q
G
-----
A
E
-
L
E
I
T
D
L
V
E
R
K
-
D
S
L
T
-
F
K
A
N
F
---
L
-
E
-
Q
A
L
D
L
P
V
T
G
K
Y
N
---
A
T
N
A
M
I
A
S
Y
V
A
L
Q
E
------
G
V
S
E
E
Q
I
R
L
A
F
Q
H
L
E
L
T
R
N
R
T
E
W
K
K
-----
A
A---------
N
-
G
A
D
---
I
L
S
D
--
V
Y
N
-
A
N
P
T
-----
A
M
K
L
I
L
E
T
F
S
A
I
-
P
ANE
G
G
K
K
I
A
V
L
A
D
---
M
K
EL
G
---
D
Q
S
V
Q
L
H
N
Q
M
I
L
S
L
S
P
D
V
-
L
D
I
V
I
F
Y
G
E
D
I
A
-----------------
Q
L
A
Q
L
A
S
Q
M
F
P
I
--
G
H
V
Y
Y
F
K
K
T
EDQ
D
Q
F
E
D
L
V
K
Q
V
K
E
S
----
L
G
A
H
D
--
Q
I
L
L
K
G
S
N
S
M
N
L
A
K
L
--------------------------------
25
HHSearch
53.74
21%
-9
* C1 *
-
4QDI
4
?
A:
[39-464]
-----------------
P
Q
T
E
I
K
R
I
L
T
D
S
R
H
A
E
S
G
D
A
F
L
A
L
K
G
E
R
--
F
D
A
H
N
F
V
A
Q
V
V
A
N
G
C
Q
V
A
I
V
E
R
P
-
I
D---
A
E
-
I
------
A
--
Q
L
V
V
A
D
T
--
R
L
A
L
G
Q
----
L
--
G
A
Y
R
-
R
E
Q
N
A
Q
L
K
V
I
A
L
T
G
S
S
G
K
T
T
T
K
E
M
L
G
S
I
L
S
R
L
A
-
P
T
L
-
I
T
R
G
N
L
N
N
D
-----
L
-----
G
--------------------------------
V
P
M
--
M
L
L
------
E
L
-
R
K
E
H
Q
Y
A
V
M
E
L
G
A
N
H
Q
G
E
I
D
-
Y
-
T
S
K
I
-
V
Q
P
H
V
A
G
I
L
N
I
G
T
A
H
L
G
E
F
G
-
G
R
D
G
I
C
R
A
K
S
E
I
-
Y
R
-
H
I
L
P
Q
G
--
V
A
I
V
P
Q
Q
-
D
D
F
T
-
A
E
I
R
E
A
A
K
----
S
H
Q
I
M
S
F
G
E
G
-----
G
D
-
V
F
A
T
E
I
E
L
L
P
-
Q
S
A
N
-
F
Q
L
H
T
P
Q
-
G
-
S
-
S
F
V
R
L
P
F
A
G
E
H
N
---
V
Q
N
A
T
A
A
V
A
F
A
L
A
L
------
G
V
S
L
E
D
I
V
K
G
L
E
Q
A
Q
G
A
K
G
R
L
N
F
I
Q
-----
K
----------
A
-
P
H
L
---
F
I
D
D
T-
Y
-
N
-
A
N
P
T
-----
S
M
R
A
A
A
Q
V
L
L
Q
Q
-----
N
G
I
K
V
M
V
M
G
D
---
I
---
G
ELG
D
S
S
W
Q
E
H
H
D
L
G
R
D
L
A
E
L
P
-
L
D
H
I
V
A
V
G
Q
F
A
S
A
-----------------
A
L
E
G
A
G
--
L
H
S
--
T
K
L
K
A
F
------
Q
T
Q
A
E
A
L
P
F
L
I
N
L
I
Q
TH
Q
P
Q
S
M
--
S
F
L
F
K
G
S
R
F
T
H
M
E
T
L
--------------------------------
5
PsiBlast_PDB
52.30
24%
-13
- C1 -
-
4QDI
4
?
A:
[37-356]
---------------
Q
I
P
Q
T
E
I
K
R
I
L
T
D
S
R
H
A
E
S
G
D
A
F
L
A
L
K
G
--
E
R
F
D
A
H
N
F
V
A
Q
V
V
A
N
G
C
Q
V
A
I
V
E
R
P
-
I
----
D
A
-
E
I-----
A
--
Q
L
V
V
A
D
T
--
R
L
A
L
G
Q
----
L
G
A
Y
R
R
E
Q
N
---
A
Q
L
K
V
I
A
L
T
G
S
S
G
K
T
T
T
K
E
M
L
G
S
I
L
S
R
L
A
-
P
T
L
-
I
T
R
G
------------------
N
L
N
N
D
-----------------------
L
G
V
P
M
M
L
L
E
L
R
K
E
-
H
--
Q
Y
A
-----
V
M
E
L
G
A
N
H
Q
G
E
-
I
D
Y
-
T
-
S
-
K
I
-
V
Q
P
H
V
A
G
I
L
N
I
G
T
A
H
L
G
E
F
G
-
G
R
D
G
I
C
R
A
K
S
E
I
-
Y
R
H
I
L
P
Q
G
---
V
A
I
V
P
Q
Q
-
D
D
F
T
-
A
E
I
R
E
A
A
K
S
H
----
Q
I
M
S
F
G
-----
E
G
G
D
-
V
F
A
T
E
I
E
L
L
P
-
Q
S
A
N
-
F
Q
L
H
T
P
Q
-
G
-
S
-
S
F
V
R
L
P
F
A
G
E
H
N
---
V
Q
N
A
T
A
A
V
A
F
A
L
A
L
------
G
V
S
L
E
D
I
V
K
G
L
E
Q
A
Q
G
A
K
G
R
L
N
F
I
Q
-----
K
----------
A
-
P
H
L
---
F
I
D
D
T-
Y
-
N
-
A
N
P
T
-----
S
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
52.04
23%
-2
- C1 -
-
4CVK
5
?
A:
[20-446]
----------------
G
E
D
A
V
F
S
A
V
S
T
D
S
R
A
I
G
P
G
E
L
F
I
A
L
S
G
P
R
--
F
D
G
H
D
Y
L
A
E
V
A
A
K
G
A
V
A
A
L
V
E
R
E
-
V
A---
A
P
-
L
------
P
--
Q
L
L
V
R
D
T
--
R
A
A
L
G
R
----
L
--
G
A
L
N
R
R
K
--
F
T
G
P
L
A
A
M
T
G
S
S
G
K
T
T
V
K
E
M
L
A
S
I
L
R
T
Q
A
G
D
A
E
-
S
V
L
A
T
R
G
N
L
-----
N
-----
N
D
-------------------------------
L
G
V
P
L
T
L
L
Q
------
L
-
A
P
Q
H
R
S
A
V
I
E
L
G
A
S
R
I
G
E
I
A
Y
T
-
V
-
E
L
-
T
R
P
H
V
A
I
I
T
N
A
-------
F
G
-
G
P
E
K
I
V
E
A
K
G
E
I
-
L
E
-
G
L
A
A
D
G
--
T
A
V
L
N
L
D
-
D
K
A
F
-
D
T
W
K
A
R
A
S
----
G
R
P
L
L
T
F
S
L
D
R
--
P
Q
A
D
-
F
R
A
A
D
L
Q
R
D
A
R
G
C
M
G
-
F
R
L
Q
G
V
A
-
G
-
E
-
A
Q
V
Q
L
N
L
L
G
R
H
N
---
V
A
N
A
L
A
A
A
A
A
A
H
A
L
------
G
V
P
L
D
G
I
V
A
G
L
Q
A
L
Q
P
V
K
G
R
A
V
A
Q
L
-----
T
A---------
S
-
G
L
R
---
V
I
D
D
S-
Y
-
N
-
A
N
P
A
-----
S
M
L
A
A
I
D
I
L
S
G
F
-
S
----
G
R
T
V
L
V
L
G
D
---
M
---
G
-----
A
E
Q
A
H
R
E
V
G
A
Y
A
A
G
-
K
-
V
S
A
L
Y
A
V
G
P
L
M
A
-----------------
H
A
V
Q
A
F
----
G
A
---
T
G
R
H
F
------
A
D
Q
A
S
L
I
G
A
L
A
T
-----
E
D
P
T
T
--
T
I
L
I
K
G
S
R
S
A
A
M
D
K
V
--------------------------------
7
PsiBlast_PDB
52.03
24%
-18
- C1 -
-
4ZIY
4
?
A:
[39-368]
---------------
Q
I
P
Q
T
E
I
K
R
I
L
T
D
S
R
H
A
E
S
G
D
A
F
L
A
L
K
G
--
E
R
F
D
A
H
N
F
V
A
Q
V
V
A
N
G
C
Q
V
A
I
V
E
R
P
-
I
----
D
A
-
E
I-----
A
--
Q
L
V
V
A
D
T
--
R
L
A
L
G
Q
----
L
G
A
Y
R
R
E
Q
N
---
A
Q
L
K
V
I
A
L
T
G
S
S
G
K
T
T
T
K
E
M
L
G
S
I
L
S
R
L
A
-
P
T
L
-
I
T
R
G
------------------
N
L
N
N
D
-----------------------
L
G
V
P
M
M
L
L
E
L
R
K
E
-
H
--
Q
Y
A
-----
V
M
E
L
G
A
N
H
Q
G
E
-
I
D
Y
-
T
-
S
-
K
I
-
V
Q
P
H
V
A
G
I
L
N
I
G
T
A
H
---
F
G
-
G
R
D
G
I
C
R
A
K
S
E
I
-
Y
R
H
I
L
P
Q
G
---
V
A
I
V
P
Q
Q
-
D
D
F
T
-
A
E
I
R
E
A
A
K
S
H
----
Q
I
M
S
F
G
-----
A
G
G
D
-
V
F
A
T
E
I
E
L
L
P
-
Q
S
A
N
-
F
Q
L
H
T
P
Q
-
G
-
S
-
S
F
V
R
L
P
F
A
G
E
H
N
---
V
Q
N
A
T
A
A
V
A
F
A
L
A
L
------
G
V
S
L
E
D
I
V
K
G
L
E
Q
A
Q
G
A
K
G
R
L
N
F
I
Q
-----
K
----------
T
-
P
H
L
---
F
I
D
D
T-
Y
-
N
-
A
N
P
T
-----
S
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
50.82
20%
-28
- C1 -
-
3ZM6
1
?
A:
[22-448]
-----------------
E
D
T
Q
L
E
K
A
E
F
D
S
R
L
I
G
T
G
D
L
F
V
P
L
K
G
A
---
R
D
G
H
D
F
I
E
T
A
F
E
N
G
A
A
V
T
L
S
E
K
E
-
V
----
S
N
-
H
------
P
--
Y
I
L
V
D
D
V
--
L
T
A
F
Q
S
----
L
--
A
S
Y
Y
L
E
K
--
T
T
V
D
V
F
A
V
T
G
S
N
G
K
T
T
T
K
D
M
L
A
H
L
L
S
T
R
Y
-
K
T
Y
-
K
T
Q
G
N
Y
N
N
E
-----
I
-----
G
L
--------------------------------
P
--
Y
T
V
L
------
H
M
-
P
E
G
T
E
K
L
V
L
E
M
G
Q
D
H
L
G
D
I
H
-
L
-
L
-
S
E
L
A
R
P
K
T
A
I
V
T
L
V
G
E
A
H
L
A
F
F
K
-
D
R
S
E
I
A
K
G
K
M
Q
I
-
A
D
-
G
M
A
S
G
---
S
L
L
L
A
P
A
-
D
P
I
V
-
E
D
Y
L
P
I
------
D
K
K
V
V
R
F
G
Q
G
-----
A
E
-
L
E
I
T
D
L
V
E
R
K
-
D
S
L
T
-
F
K
A
N
F
---
L
-
E
-
Q
A
L
D
L
P
V
T
G
K
Y
N
---
A
T
N
A
M
I
A
S
Y
V
A
L
Q
E
------
G
V
S
E
E
Q
I
R
L
A
F
Q
H
L
E
L
T
R
N
R
T
E
W
K
K
-----
A
A---------
N
-
G
A
D
---
I
L
S
D
--
V
Y
N
-
A
N
P
T
-----
A
M
K
L
I
L
E
T
F
S
A
I
-
P
ANE
G
G
K
K
I
A
V
L
A
D
---
M
KEL
G
---
D
Q
S
V
Q
L
H
N
Q
M
I
L
S
L
S
P
D
V
-
L
D
I
V
I
F
Y
G
E
D
I
A
Q
-----------------
L
A
Q
L
A
S
Q
M
F
P
I
--
G
H
V
Y
Y
F
K
K
T
EDQ
D
Q
F
E
D
L
V
K
Q
V
K
E
S
----
L
G
A
H
D
--
Q
I
L
L
K
G
S
N
S
M
N
L
A
K
L
--------------------------------
33
HHSearch
49.85
22%
13
- C1 -
-
3LK7
-
MURD_STRA5
A:
[30-432]
--------------------------------
K
L
G
A
I
V
T
V
N
D
G
K
P
--
F
D
E
N
P
T
A
Q
S
L
L
E
E
G
I
K
V
V
C
G
S
H
P
-
L
E
L
L
D
E
D
-
F
C
Y
M
I
K
N
P
--
G
I
P
Y
N
N
P
M
V
K
K
A
L
E
K
QI
P
V
L
--
T
E
V
E
L
A
Y
L
V
S
E
S
Q
L
I
G
I
T
G
S
N
G
K
T
T
T
T
T
M
I
A
E
V
L
N
A
G
G
-
Q
R
G
-
L
L
A
G
N
I
G
F
P
-----
A
-----
S
-------------------------------------
E
V
V
Q
------
A
-
A
N
D
K
D
T
L
V
M
E
L
S
S
F
Q
L
-
M
---
G
-
V
-
K
E
-
F
R
P
H
I
A
V
I
T
N
L
M
P
T
H
L
D
Y
H
G
-
S
F
E
D
Y
V
A
A
K
W
N
I
-
Q
N
-
Q
M
S
S
S
D
--
F
L
V
L
N
F
N
-
Q
G
I
S
-
K
E
L
A
K
T
T
-----
K
A
T
I
V
P
F
S
T
T
E
---
K
V
D
G
A
Y
V
Q
D
-------
K
Q
L
-
F
-
Y
K
-
G
E
-
N
-
I
M
S
V
D
D
I
G
V
P
G
S
H
N
---
V
E
N
A
L
A
T
I
A
V
A
K
L
A
------
G
I
S
N
Q
V
I
R
E
T
L
S
N
F
G
G
V
K
H
R
L
Q
S
L
G
-----
K
V---------
H
-
G
I
S
---
F
Y
N
D
--
S
-
K
S
T
N
I
L
-----
A
T
Q
K
A
L
S
G
F
D
N
-------
T
K
V
I
L
I
A
G
G
-------
L
---
D
R
G
N
E
F
-
D
E
L
I
P
D
I
T
--
G
-
L
K
H
M
V
V
L
G
E
S
A
S
-----------------
R
V
K
R
A
A
Q
K
A
-
G
---
V
T
Y
S
D
A
------
L
D
V
R
D
A
V
H
K
A
Y
E
V
----
A
Q
Q
G
D
--
V
I
L
L
S
P
A
N
A
S
-
W
D
M
Y
-
K
------------------------------
4
PsiBlast_PDB
49.52
26%
-15
- C1 -
-
1GG4
-
MURF_ECOLI
A:
[30-347]
---------------------------
D
T
R
K
L
T
P
G
C
L
F
V
A
L
K
G
--
E
R
F
D
A
H
D
F
A
D
Q
A
K
A
G
G
A
G
A
L
L
V
S
R
P
-
L
----
D
I
D
L
------
P
--
Q
L
I
V
K
D
T
--
R
L
A
F
G
E
----
L
A
A
W
V
R
Q
Q
V
----
P
A
R
V
V
A
L
T
G
S
S
G
K
T
S
V
K
E
M
T
A
A
I
L
S
Q
C
G
-
N
T
L
-
Y
T
A
G
N
L
N
N
D
-----
I
G
V
P
M
T
L
L
R
L
T
P
E
-------------------------------------
Y
--
D
Y
A
-----
V
I
E
L
G
A
N
H
Q
G
E
-
I
A
W
-
T
-
V
-
S
L
-
T
R
P
E
A
A
L
V
N
N
L
A
---------
S
L
A
G
V
A
K
A
K
G
E
I
-
F
S
G
L
P
E
N
G
---
I
A
I
M
N
A
D
-
N
--
N
-
D
W
L
--
N
W
Q
S
V
I
G
S
R
K
V
W
R
F
S
P
N
A
--
A
N
S
D
-
F
T
A
T
N
I
H
V
T
S
-
H
G
T
E
-
F
T
L
Q
T
P
T
-
G
-
S
-
V
D
V
L
L
P
L
P
G
R
H
N
---
I
A
N
A
L
A
A
A
A
L
S
M
S
V
------
G
A
T
L
D
A
I
K
A
G
L
A
N
L
K
A
V
P
G
R
L
F
P
I
Q
-----
L
----------
A
-
E
N
Q
---
L
L
L
D
--
D
-
S
-
Y
N
A
N
V
G
S
M
T
A
A
V
Q
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
49.20
21%
-5
- C1 -
-
3ZL8
2
?
A:
[2-415]
-----------------
K
D
L
L
T
R
R
F
V
L
N
S
K
E
V
R
E
G
D
V
F
V
A
V
K
G
K
R
--
F
D
G
H
D
F
I
D
E
A
L
R
N
G
A
Y
A
I
I
A
E
R
K
-
T
V---
N
S
-
D
------
R
--
I
F
L
V
E
S
S
--
V
D
T
L
A
K
----
L
--
A
R
E
K
L
G
N
F
--
S
G
T
V
V
G
V
T
G
S
S
G
K
T
T
T
K
E
I
L
Y
N
L
L
K
N
K
R
-
S
V
F
-
K
T
P
G
N
M
N
T
E
-----
Y
-----
G
L
--------------------------------
P
--
L
S
I
---
L
N
--
D
--
Y
K
G
E
E
I
L
V
L
E
M
A
A
S
R
P
G
D
I
A
-
H
L
C
-
K
I
-
A
P
P
D
V
A
V
L
L
N
V
G
S
A
H
L
E
F
F
G
-
T
R
E
R
I
M
E
T
K
M
E
I
-
I
K
-
H
S
K
E
N
A
--
I
A
V
T
L
F
D
-
D
P
D
L
-
R
K
E
V
P
R
------
Y
R
N
T
L
F
F
G
K
E
G
--
G
--
D
-
S
V
L
K
D
W
W
Y
Y
E
-
G
S
T
I
-
A
E
F
E
A
---
F
-
D
-
S
L
F
T
V
K
L
S
G
Y
W
N
G
G
Q
L
L
N
I
A
A
S
L
C
V
M
R
T
L
------
G
E
T
V
D
I
--
F
D
L
A
S
L
K
T
V
P
G
R
F
N
V
R
E
-----
K
----------
K
-
G
V
L
---
I
V
D
D
T-
Y
-
N
-
A
S
P
E
-----
A
F
Q
T
S
I
E
A
L
L
R
F
-
P
----
G
K
K
F
A
V
V
G
A
---
M
K
EL
G
---
E
R
S
K
E
F
H
E
E
L
G
E
R
L
N
V
-
L
D
G
V
Y
V
F
L
S
E
P
E
A
E
W
-----------------
I
K
----
S
K
K
-----
I
I
L
K
S
------
D
D
P
E
K
I
A
K
D
L
A
T
R
----
V
K
K
G
D
--
V
V
L
F
K
A
S
R
A
V
R
I
E
R
V
--------------------------------
3
PsiBlast_PDB
47.72
28%
-0
- C1 -
-
4CVM
5
?
A:
[25-360]
---------------------
F
S
A
V
S
T
D
S
R
A
I
G
P
G
E
L
F
I
A
L
-
S
G
P
R
F
D
G
H
D
Y
L
A
E
V
A
-
A
K
G
A
V
A
A
L
V
E
R
E
-
V
----
A
D
-
A
------
P
LP
Q
L
L
V
R
D
T
--
R
A
A
L
G
R
----
L
G
A
--
L
N
R
R
K
F
T
G
P
L
--
A
A
M
T
G
S
S
G
K
T
T
V
K
E
M
L
A
S
I
L
R
T
Q
A
-
G
D
A
E
S
V
L
A
T
R
G
---------------
N
L
N
N
D
-----------------------
L
G
V
P
L
T
L
L
Q
L
A
P
--------
Q
H
R
S
A
V
I
E
L
G
A
S
R
I
G
E
-
I
A
Y
-
T
-
V
-
E
L
-
T
R
P
H
V
A
I
I
T
N
A
G
T
A
H
V
---
G
-
G
P
E
K
I
V
E
A
K
G
E
I
-
L
E
G
L
A
A
D
G
---
T
A
V
L
N
L
D
-
D
K
A
F
-
D
T
W
K
A
R
A
S
G
R
P
----
L
L
T
F
S
L
D
R
--
P
Q
A
D
-
F
R
A
A
D
L
Q
R
D
A
-
R
G
C
M
G
F
R
L
Q
G
V
A
-
G
-
E
-
A
Q
V
Q
L
N
L
L
G
R
H
N
---
V
A
N
A
L
A
A
A
A
A
A
H
A
L
------
G
V
P
L
D
G
I
V
A
G
L
Q
A
L
Q
P
V
K
G
R
A
V
A
Q
L
-----
T
----------
A
-
S
G
L
---
R
V
I
D
DS
Y
-
N
-
A
N
P
A
-----
S
M
L
A
A
I
D
I
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.39
28%
0
- C1 -
-
4CVK
5
?
A:
[25-360]
---------------------
F
S
A
V
S
T
D
S
R
A
I
G
P
G
E
L
F
I
A
L
-
S
G
P
R
F
D
G
H
D
Y
L
A
E
V
A
-
A
K
G
A
V
A
A
L
V
E
R
E
-
V
----
A
--
A
------
P
LP
Q
L
L
V
R
D
T
--
R
A
A
L
G
R
----
L
G
A
--
L
N
R
R
K
F
T
G
P
L
--
A
A
M
T
G
S
S
G
K
T
T
V
K
E
M
L
A
S
I
L
R
T
Q
A
-
G
D
A
E
S
V
L
A
T
R
G
---------------
N
L
N
N
D
-----------------------
L
G
V
P
L
T
L
L
Q
L
A
P
--------
Q
H
R
S
A
V
I
E
L
G
A
S
R
I
G
E
-
I
A
Y
-
T
-
V
-
E
L
-
T
R
P
H
V
A
I
I
T
N
A
-------
F
G
-
G
P
E
K
I
V
E
A
K
G
E
I
-
L
E
G
L
A
A
D
G
---
T
A
V
L
N
L
D
-
D
K
A
F
-
D
T
W
K
A
R
A
S
G
R
P
----
L
L
T
F
S
L
D
R
--
P
Q
A
D
-
F
R
A
A
D
L
Q
R
D
A
-
R
G
C
M
G
F
R
L
Q
G
V
A
-
G
-
E
-
A
Q
V
Q
L
N
L
L
G
R
H
N
---
V
A
N
A
L
A
A
A
A
A
A
H
A
L
------
G
V
P
L
D
G
I
V
A
G
L
Q
A
L
Q
P
V
K
G
R
A
V
A
Q
L
-----
T
----------
A
-
S
G
L
---
R
V
I
D
DS
Y
-
N
-
A
N
P
A
-----
S
M
L
A
A
I
D
I
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
45.82
18%
-26
- C1 -
-
4HV4
2
MURC_YERPE
B:
[121-471]
-------------------------------------------------------------------------------------------------------------------------
Y
R
H
G
I
A
V
A
G
T
H
G
K
T
T
T
T
A
M
L
S
S
I
Y
A
E
A
G
-
L
D
P
-
T
F
V
N
G
-
G
-------
L
-----
V
--------------------------------
K
--
A
A
G
T
H
-------
A
R
L
G
S
S
R
Y
L
I
A
E
A
D
E
S
D
A
-
S
-----
F
-
L
H
-
L
Q
P
M
V
A
I
V
T
N
I
E
A
D
-------
D
F
E
N
L
K
Q
T
F
I
N
F
-
L
H
-
N
L
P
F
Y
G
--
R
A
V
M
C
I
D
-
D
P
V
V
-
R
E
L
L
P
R
V
-----
G
R
H
I
T
T
Y
G
F
S
D
---
D
A
D
-
V
Q
I
A
S
Y
R
Q
E
G
-
P
Q
G
H
-
F
T
L
R
R
Q
D
-
K
P
L
-
I
E
V
T
L
N
A
P
G
R
H
N
---
A
L
N
A
A
A
A
V
A
V
A
T
E
E
------
G
I
E
D
E
D
I
L
R
A
L
V
G
F
Q
G
T
G
R
R
F
D
F
L
G
-----
N
F
P
LAPVNGK
E
G
-
S
A
M
---
L
V
D
D
--
Y
-
G
-
H
H
P
T
-----
E
V
D
A
T
I
K
A
A
R
A
G
W
P
---
D
K
R
I
V
M
L
F
Q
P
---
H
---
R
Y
--
T
R
T
R
D
L
Y
D
D
F
A
N
V
L
S
Q
---
V
D
V
L
L
M
L
D
V
Y
A
A
G
E
PPIPGA
D
S
------
R
A
L
C
R
T
I
R
N
R
G
K
---
L
D
P
I
L
V
------
P
D
S
E
S
A
P
E
M
L
A
Q
I
----
L
N
G
E
D
--
L
I
L
V
Q
G
A
G
N
I
-------------------------------------
46
HHSearch
44.62
20%
-32
- C1 -
-
2GCA
-
FPGS_LACCA
A:
[20-416]
---------------------------------------------------------------------------------------------
G
D
H
--
R
R
I
L
T
L
----
L
--
H
A
--
L
G
N
P
Q
Q
Q
G
R
Y
I
H
V
T
G
T
N
G
K
G
S
A
A
N
A
I
A
H
V
L
E
A
S
G
-
L
T
V
-
G
L
Y
T
S
P
F
I
M
RFNER
I
-----
M
I
D
H
E
P
I
P
D
A
A
L
V
N
A
V
A
F
V
R
A
A
L
E
R
L
Q
Q
Q
Q
A
D
F
N
V
T
E
F
E
F
I
T
A
L
G
Y
W
Y
F
R
Q
R
Q
V
D
V
A
V
I
E
V
G
I
G
G
D
T
D
S
----
T
-
N
V
-
I
T
P
V
V
S
V
L
T
E
V
A
L
D
H
Q
K
L
L
G
H
T
I
T
A
I
A
K
H
K
A
G
I
-
I
K
-
R
G
I
P
------
V
V
T
G
N
L
V
P
D
A
A
A
V
V
A
A
K
---------
V
A
T
T
G
S
Q
W
L
R
F
D
R
D
-
F
S
V
P
K
A
K
L
H
G
-
W
G
Q
R
-
F
T
Y
E
D
Q
D
G
R
-
I
-
S
D
L
E
V
P
L
V
G
D
Y
Q
---
Q
R
N
M
A
I
A
I
Q
T
A
K
V
Y
A
K
Q
T
E
W
P
L
T
P
Q
N
I
R
Q
G
L
A
A
S
-
H
W
P
A
R
L
E
K
I
S
-----
D
------------
T
P
L
---
I
V
I
D
--
G
-
A
-
H
N
P
D
-----
G
I
N
G
L
I
T
A
L
K
Q
L
-
F
---
S
Q
P
I
T
V
I
A
G
I
---
L
-------------
Y
A
A
M
A
D
R
L
T
A
-
A
-
F
S
T
V
Y
L
V
P
V
P
G
T
---------
P
------
R
A
L
---------------
R
L
K
------
D
S
W
Q
E
A
L
A
A
S
L
N
-----
D
V
P
D
Q
--
P
I
V
I
T
G
S
L
Y
L
A
------------------------------------
38
HHSearch
44.61
18%
-22
- C1 -
-
2F00
-
MURC_ECOLI
B:
[118-469]
-------------------------------------------------------------------------------------------------------------------------
F
R
H
G
I
A
I
A
G
T
H
G
K
T
T
T
T
A
M
V
S
S
I
Y
A
E
A
G
-
L
D
P
-
T
F
V
N
G
--
G
L
-----------
V
--------------------------------
K
A
--
A
G
V
H
A
R
-------
L
G
H
G
R
Y
L
I
A
E
A
D
E
S
D
A
-
S
-----
F
-
L
H
-
L
Q
P
M
V
A
I
V
T
N
I
E
A
D
H
M
D
T
Y
Q
G
D
F
E
N
L
K
Q
T
F
I
N
F
-
L
H
-
N
L
P
F
Y
G--
R
A
V
M
C
V
D
-
D
P
V
I
-
R
E
L
L
P
R
V
-----
G
R
Q
T
T
T
Y
G
F
S
E
---
D
A
D
-
V
R
V
E
D
Y
Q
Q
I
G
-
P
Q
G
H
-
F
T
L
L
R
Q
D
-
K
E
P
-
M
R
V
T
L
N
A
P
G
R
H
N
---
A
L
N
A
A
A
A
V
A
V
A
T
E
E
------
G
I
D
D
E
A
I
L
R
A
L
E
S
F
Q
G
T
G
R
R
F
D
F
L
G
-----
E
FPLEPVNGK-
S
G
T
A
M
---
L
V
D
D
--
Y
-
G
-
H
H
P
T
-----
E
V
D
A
T
I
K
A
A
R
A
G
W
P
---
D
K
N
L
V
M
L
F
Q
P
---
H
R--
F
---
T
R
T
R
D
L
Y
D
D
F
A
N
V
L
T
--
Q
-
V
D
T
L
L
M
L
E
V
Y
P
A
G
E
------
A
P
IPGADS
R
S
L
C
R
T
I
R
G
R
G
K
---
I
D
P
I
L
V
------
P
D
P
A
R
V
A
E
M
L
A
P
V
----
L
T
G
N
D
--
L
I
L
V
Q
G
A
G
N
I
G
------------------------------------
6
PsiBlast_PDB
43.31
24%
-32
- C1 -
-
3LK7
-
MURD_STRA5
A:
[103-422]
-----------------------------------------------------------------------------------------------------------------
V
E
L
A
Y
L
V
S
E
S
Q
L
I
G
I
T
G
S
N
G
K
T
T
T
T
T
M
I
A
E
V
L
N
A
G
G
-
Q
R
G
-
L
L
A
G
N
I
G
-----------------------------------------------
F
P
A
S
E
V
V
Q
A
A
N
--
D
K
D
T
L
V
M
E
L
S
S
F
Q
L
M
--
G
V
-
K
E
F
-
R
-
P
-
H
------
I
A
V
I
T
N
L
M
P
T
H
L
D
Y
H
G
-
S
F
E
D
Y
V
A
A
K
W
N
I
Q
N
Q
-
M
S
S
S
D
---
F
L
V
L
N
F
N
-
Q
G
I
S
-
K
E
L
A
K
T
-----
T
K
A
T
I
V
P
F
S
T
T
E
--
K
V
D
G
-
A
Y
V
Q
D
K
Q
L
F
Y
-
K
G
E
N
-
I
M
S
V
D
D
I
-
G
---------
V
P
G
S
H
N
---
V
E
N
A
L
A
T
I
A
V
A
K
L
A
------
G
I
S
N
Q
V
I
R
E
T
L
S
N
F
G
G
V
K
H
R
L
Q
S
L
G
-----
K
----------
V
-
H
G
I
S
--
F
Y
N
D
--
S
-
K
-
S
T
----------
N
I
L
A
T
Q
K
A
L
-
S
---
G
F
D
N
T
K
V
I
L
I
---
A
---
G
---
G
L
D
R
G
N
E
F
D
E
L
I
P
D
I
T
-
G
L
K
H
M
V
V
L
G
E
S
A
S
R
V
K
------
R
A
------
A
Q
-----
K
A
G
V
T
Y
S
-----
D
A
------
L
D
V
R
D
A
V
H
K
A
Y
E
V
----
A
Q
Q
G
D
--
V
I
L
L
S
------------------------------------------
42
HHSearch
42.47
19%
-7
- C1 -
-
1P3D
2
MURC_HAEIN
A:
[117-463]
-------------------------------------------------------------------------------------------------------------------------
F
R
H
G
I
A
V
A
G
T
H
G
K
T
T
T
T
A
M
I
S
M
I
Y
T
Q
A
K
-
L
D
P
T
F
V
N
G
G
L
V
K
----------------------------------------------
S
A
--
G
-
K
N
------
A
H
L
G
A
S
R
Y
L
I
A
E
A
D
E
S
D
A
-
S
-----
F
-
L
H
-
L
Q
P
M
V
S
V
V
T
N
M
E
P
D
H
M
D
T
Y
E
G
D
F
E
K
M
K
A
T
Y
V
K
F
-
L
H
-
N
L
P
F
Y
G
--
L
A
V
M
C
A
D
-
D
P
V
L
-
M
E
L
V
P
K
V
-----
G
R
Q
V
I
T
Y
G
F
S
E
---
Q
A
D
-
Y
R
I
E
D
Y
E
Q
T
G
-
F
Q
G
H
-
Y
T
V
I
C
P
N
-
N
E
R
-
I
N
V
L
L
N
V
P
G
K
H
N
---
A
L
N
A
T
A
A
L
A
V
A
K
E
E
------
G
I
A
N
E
A
I
L
E
A
L
A
D
F
Q
G
A
G
R
R
F
D
Q
L
G
E
F
I
R
P
N
----------
G
-
K
V
R
---
L
V
D
D
--
Y
-
G
-
H
H
P
T
-----
E
V
G
V
T
I
K
A
A
R
E
G
W
G
---
D
K
R
I
V
M
I
F
Q
P
---
H
---
R
Y
--
S
R
T
R
D
L
F
D
D
F
V
Q
V
L
S
--
Q
-
V
D
A
L
I
M
L
D
V
Y
A
A
G
E
------
A
P
IVGAD
S
K
S
L
C
R
S
I
R
N
L
G
K
---
V
D
P
I
L
V
------
S
D
T
S
Q
L
G
D
V
L
D
Q
I
----
I
Q
D
G
D
--
L
I
L
A
Q
G
A
G
S
V
S
------------------------------------