@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VPU2: (2017-11-23 )
MIAPRQGLFASLLIISFALHTFLLVIATTHQLNENRASQGQLMTSQLVADSLSELEPANTVSLALIANRYATNPSVASIRILDANKQVLATSGMSKTRQGEIFVRDALQNEKKVGSIEITLIQPSIGEILRTQWLAILASLFLHVLLWLAYRAIARPTRSEYLARINEENRLKHEIQELTQALALEKQNTVTLVAQAQQQAKVKPIVRSQPEKSLESTDQNTLALNIQFYDPKQLLSSVNQSVSVPYFKLCQLFLNKSIELCTKHYHLKATDIDVVDEFHAEGATLAISTSHPHAVECLLMVGTVFQLLSDVLYKRYREDKRFALQTRSAVCNAVEAMQIDAKEAAQRLAQHLHAKESALYLDNEQLKAIQDSYQLVAMPNPSNVMTRHAFMINGMNAECAELAQNIRTEILMGKKSIPQNASPSSAAS
Atome Classification :
(20 SA)
----.......--..---10....---------------------....20........30....--------....40......---..50........60........70----------.........80.....--...90..---......100.......110.......120.......130.......---140.......150.......160.......170.......180.......-190.......-200.......210.------------.....-.220...--....230-----.......----..----240------.........250.......260-.---........270.....------..280.......290.--.---.......300.-------------......310.......--------320----.--........330-----.--....---.----.-----..---340--.........350..--.....-360.......370-----.......380...--.----...----.390..---.....400.......410.......420.......-------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----MIAP
R
Q
G
--
L
F
---
A
S
L
L
I
I
---------------------
S
F
A
L
H
T
F
L
L
V
I
ATTHQLNEN--------RASQG
Q
L
M
T
S
Q
L
---
V
A
D
S
L
S
ELEPA
N
T
V
S
L
A
L
I
A
N
RY-----------ATNPS
V
A
S
I
R
I
LDANK--
Q
V
L
ATSG---MSKTRQG
E
I
F
V
R
D
A
LQNEKKVG
S
I
E
I
T
L
IQ
P
S
I
G
E
I
L
R
T
Q
W
L
A
I
L
A
---
S
L
F
L
H
V
L
L
W
L
A
Y
R
A
IARP
T
R
S
E
Y
L
A
RINE
E
N
R
L
K
H
E
I
Q
E
L
T
Q
A
L
ALEKQN-
T
V
T
L
V
A
Q
A
Q
Q
-QAKVK
P
I
VRSQ
P
E
K
------------
S
LEST-DQ
N
T
L
A
L
--
N
I
Q
FY-------
D
P
K
Q
L
L
S
----
S
V
----
N
--------QSVS
V
P
Y
F
K
L
C
Q
L
F
L
NK
S
I
E
---
L
---
C
T
KHYHLKAT
D
I
D
V
V
D
------
E
FHAEG
A
T
L
A
I
ST--S--H---
P
H
A
V
E
C
L
L
M
V
G
-------------
T
V
F
Q
L
L
S
D
V
L
Y
K
R
Y
RE--------D------K--
R
F
A
L
Q
T
R
S
A
-------
V
--
C
N
A
V
---
E
----
A
-----MQ---I----
D
A
K
E
A
A
Q
R
L
A
Q
H
L
H
--
A
K
ES
A
-
L
Y
LD
N
E
Q
L
K
A
I
QD-----S
Y
Q
L
V
AMP-NPSN--
V
----
M
T
R
----
H
A
F
M
IN---GMN
A
E
C
A
E
L
A
Q
N
I
R
T
E
I
LMGKKSIPQNASPSSAAS-------
36
Fugue
66.80
19%
1
- C4 -
-
5K5S
5
CASR_HUMAN
A:
[20-598]
YGPD
Q
R
A
Q
K
K
G
D
I
I
L
---
G
G
L
F
P
I
HFGVAAKDQDLKSRP
E
S
V
E
C
I
R
Y
N
F
R
G
F
R
W
L
Q
A
M
I
F
A
I
E
E
I
--------
N
S
S
P
A
L
L
P
N
L
T
L
G
Y
R
I
F
D
T
C
N
T
V
S
K
A
L
E
A
T
L
S
F
V
A
Q
N
K
IPSTIAVVGAT
G
S
G
V
S
T
A
V
A
N
L
L
G
L
F
Y
I
P
Q
V
S
Y
A
S
S
SRL
L
S
N
K
N
Q
F
K
S
F
L
R
-
T
I
P
N
D
E
H
Q
A
T
A
M
A
D
I
I
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Y
-----
F
R
W
N
W
V
G
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I
A
A
DD
D
Y
G
R
P
G
I
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K
F
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A
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I
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S
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L
I
S
Q
Y
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D
-
E
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V
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V
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Q
N
S
T
A
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-
V
I
V
V
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P
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P
L
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R
N
I
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EAWASS
S
L
I
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-
P
Q
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V
GG
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P
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F
R
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F
L
K
----
K
V
----
H
--------
P
R
K
S
V
H
N
-
G
F
A
K
E
F
W
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T
F
N
CHP
L
---
C
T
G
D
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N
I
N
S
V
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T
P
Y
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D
YTHL
R
I
S
Y
N
V
Y
L
A
V
Y
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I
A
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--
A
--
L
---
Q
D
I
Y
T
C
L
P
G
R
G
LFTNG
S
C
A
D
IKKV
E
A
W
Q
V
L
K
H
L
R
H
L
Q
F
T
N
NMG
E
Q
V
T
F
D
------
E
--
C
G
D
L
V
G
N
Y
S
-------
I
--
I
N
W
H
L
S
P
E
----
D
-----
G
S
---
I
----
V
F
K
E
V
G
Y
Y
---
N
V
Y
--
A
K
K
G
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R
L
F
I
N
E
E
K
I
L
W
S
G
F
-----
S
R
E
-
V
P
F
S
-
N
C
S
R
DC
L
----
A
G
T
----
R
K
G
I
I
E
---
G
E
P
T
C
C
F
E
C
V
E
C
P
D
G
E
Y
S
D
E
T
D
A
S
A
C
N
K
C
P
D
D
F
W
S
N
ENHTSC
41
Fugue
61.73
16%
7
* C4 *
-
5HXW
4
?
A:
[22-454]
P
R
H
G
F
V
E
G
T
E
G
--
A
L
PKQ
A
D
V
V
V
V
---------------------
G
A
G
----
I
L
G
I
M
T
A
I
N
L
V
E
R
G
L
S
V
V
I
V
E
K
G
N
I
A
G
E
Q
S
S
R
F
---
Y
G
Q
A
I
S
Y
K
M
P
D
E
T
F
L
L
H
H
L
G
K
H
R
-----------
W
R
-
E
M
N
A
K
V
G
I
-
D
T
T
Y
--
R
T
Q
G
R
V
E
---
V
P
L
D
E
E
D
L
V
N
V
R
K
W
I
D
E
R
S
K
N
V
G
S
D
I
P
F
K
T
R
I
I
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A
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L
N
Q
R
L
R
G
A
T
---
T
D
W
K
I
A
G
F
E
E
D
S
G
S
F
D
P
E
V
A
T
F
V
M
A
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Y
A
K
K
M
G
V
--
R
I
Y
T
Q
C
A
A
R
G
L
E
T
Q
A
G
V
I
S
D
V
V
T
E
K
G
-
A
I
K
T
S
Q
V
V
V
A
G
G
V
W
------------
S
R
L
F
M
Q
N
L
N
V
D
V
P
--
T
L
P
A
Y
-------
Q
S
Q
Q
L
I
S
G
S
PT
A
P
----
G
--------
G
N
V
A
L
P
G
G
I
F
F
R
E
Q
A
D
G
T
-----
Y
---
A
T
S
P
R
V
I
V
A
P
---
V
V
K
------
E
S
F
T
Y
G
Y
K
Y
L
P
L
L
--
A
--
L
---
P
D
F
---------------------
P
V
H
I
S
L
N
E
Q
L
I
N
S
F
M
Q
--------
S
------
T
--
H
W
N
L
D
E
V
S
-------------
P
F
---
E
----
Q
-----
F
R
N--
M
----
T
A
L
P
D
L
P
E
L
N
A
S
L
E
--
K
L
K
A
E
-
F
P
A
F
K
E
S
K
L
I
D
Q
W
-----
S
G
A
M
A
I
A
P
-
D
E
N
P
--
I
----
I
S
E
VKEY
P
G
L
V
I
N
TAT
G
W
G
M
T
E
S
P
V
S
A
E
L
T
A
D
L
L
L
G
K
K
P
V
L
D
P
K
P
F
S
L
Y
R
F
-------
17
HHSearch
49.98
12%
-115
- C5 -
-
5M2A
-
?
A:
[147-313]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
P
Q
L
-
V
E
K
I
I
-
F
--
F
S
D
I
L
-------
A
F
S
T
L
T
E
----
K
L
----
P
--------
V
N
E
V
V
I
L
V
N
R
Y
F
S
I
C
T
R
I
I
S
---
A
---
Y
G
----------
G
E
V
T
------
K
F
I
G
D
C
V
M
A
S
F
T
K
--
E
--------
Q
G
D
A
A
I
R
T
S
-------------
L
D
I
I
S
E
L
K
Q
L
R
H
H
V
E
A
--------
T
N-----
P
--
L
H
L
L
Y
T
G
I
G
L
S
Y
G
H
V
I
E
--
G
N
M
G
---
S
----
S
L
K
---
M
D
---
H
T
L
L
G
D
A
V
N
V
A
A
R
L
E
A
L
T
R
QL
P
Y
A
L
A
-
F
T
A
--
G
V
K
K
C
C
Q
A
-----
Q
W
T
F
I
-------------------------------------------------------------------------
15
HHSearch
49.85
13%
-76
- C5 -
-
2W01
-
?
C:
[435-600]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
G
D
R
-
R
P
I
T
I
-
L
--
T
S
D
L
R
-------
G
F
T
S
T
S
E
----
G
L
----
N
--------
P
E
E
V
V
K
V
L
N
I
Y
F
G
K
M
A
D
V
I
T
---
H
---
H
G
----------
G
T
I
D
------
E
F
M
G
D
G
I
L
V
L
F
G
A
--
P
TS
Q
---
Q
D
D
A
L
R
A
V
A
C
G
-------------
V
E
M
Q
L
A
L
R
E
V
N
Q
Q
V
T
G
--------
L
------
G
--
L
Q
P
L
E
M
G
I
G
INTGEVV
V
--
G
N
I
G
---
S
EK--
R
-----
T
K
YGV
V
G---
A
Q
V
N
L
T
Y
R
I
E
S
Y
T
T
--
G
G
Q
I
F
-
I
S
S
--
T
T
L
E
A
A
G
D
-----
R
V
H
V
N
-------------------------------------------------------------------------
19
HHSearch
47.81
10%
-89
- C5 -
-
1TL7
2
A:
[20-177]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
Q
K
H
-
D
N
V
S
I
-
L
--
F
A
D
I
E
-------
G
F
T
S
L
A
S
----
Q
C
----
T
--------
A
Q
E
L
V
M
T
L
N
E
L
F
A
R
F
D
K
L
A
A
---
E
---
N
H
----------
C
L
R
I
------
K
I
L
G
D
C
Y
Y
C
V
S
G
L
--
P
EA
R
---
A
D
H
A
H
C
C
V
E
M
G
-------------
M
D
M
I
E
----
A
I
S
L
V
R
E
--------
M
------
T
--
G
V
N
V
N
M
R
V
G
I
H
S
G
R
V
H
C
--
G
V
L
G
---
L
----
R
K
W
Q
F
-
D
V
---
W
S
---
N
D
V
T
L
A
N
H
M
E
A
G
G
K
--
A
G
R
I
H
-
I
T
K
--
A
T
L
S
Y
L
N
G
-----
D
Y
----------------------------------------------------------------------------
14
HHSearch
47.33
13%
-72
- C5 -
-
2W01
-
?
A:
[435-600]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
G
D
R
-
R
P
I
T
I
-
L
--
T
S
D
L
R
-------
G
F
T
S
T
S
E
----
G
L
----
N
--------
P
E
E
V
V
K
V
L
N
I
Y
F
G
K
M
A
D
V
I
T
---
H
---
H
G
----------
G
T
I
D
------
E
F
M
G
D
G
I
L
V
L
F
G
A
--
P
TS
Q
---
Q
D
D
A
L
R
A
V
A
C
G
-------------
V
E
M
Q
L
A
L
R
E
V
N
Q
Q
V
T
G
--------
L
------
G
--
L
Q
P
L
E
M
G
I
G
I
N
T
G
E
V
V
V
--
G
N
I
G
---
S
EK--
R
-----
T
K
YGV
V
G---
A
Q
V
N
L
T
Y
R
I
E
S
Y
T
T
--
G
G
Q
I
F
-
I
S
S
--
T
T
L
E
A
A
G
D
-----
R
V
H
V
N
-------------------------------------------------------------------------
21
HHSearch
47.18
15%
-60
- C5 -
-
3R5G
1
?
B:
[3-170]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
T
Q
R
-
K
K
L
T
V
-
F
--
F
S
D
I
R
-------
G
F
T
E
L
S
E
----
E
L
----
E
--------
A
E
A
L
T
D
L
L
N
N
Y
L
N
E
M
S
K
I
A
L
---
K
---
Y
G
----------
G
T
I
D
------
K
F
V
G
D
C
V
M
V
F
F
G
D
--
P
S-
T
QG
A
K
K
D
A
V
A
A
V
S
M
G
-------------
I
A
M
R
K
H
M
K
V
L
R
Q
Q
W
R
A
--------
Q
------
G
I-
T
K
P
L
E
I
R
M
G
I
N
T
G
Y
C
T
V
--
G
N
F
G
---
A
DT--
R
-----
M
D
YTI
I
G---
R
E
V
N
L
A
S
R
L
E
S
A
S
E
--
A
G
E
I
L
-
I
S
H
--
E
T
Y
S
L
I
K
D
-----
V
I
M
C
--------------------------------------------------------------------------
12
PsiBlast_PDB
46.29
31%
-109
- C- -
-
2QR6
-
?
A:
[92-157]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-------
I
--
A
K
V
I
---
A
----
A
-----
Y
E
---
E
----
G
D
Q
A
A
A
T
R
T
L
Q
E
L
H
--
A
A
P
L
D
-
T
E
L
L
S
E
R
I
A
Q
V
R
D
-----
S
G
E
I
V
A
V
R
V
S
P
Q
N
--
V
--------------------------------------------------------------
25
HHSearch
44.50
10%
-86
- C5 -
-
1AZS
1
A:
[28-186]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
Q
K
H
-
D
N
V
S
I
-
L
--
F
A
D
I
E
-------
G
F
T
S
L
A
S
----
Q
C
----
T
--------
A
Q
E
L
V
M
T
L
N
E
L
F
A
R
F
D
K
L
A
A
---
E
---
N
H
----------
C
L
R
I
------
K
I
L
G
D
C
Y
Y
C
V
S
G
L
--
P
EA
R
---
A
D
H
A
H
C
C
V
E
M
G
-------------
M
D
M
I
E
----
A
I
S
L
V
R
E
--------
M
------
T
--
G
V
N
V
N
M
R
V
G
I
H
S
G
R
V
H
C
--
G
V
L
G
---
L
RK--
W
Q
F
---
D
V
---
W
S
---
N
D
V
T
L
A
N
H
M
E
A
G
G
K
--
A
G
R
I
H
-
I
T
K
--
A
T
L
S
Y
L
N
G
-----
D
Y
E
---------------------------------------------------------------------------
30
HHSearch
44.44
10%
-100
- C5 -
-
1WC3
2
?
B:
[21-189]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
P
E
P
-
R
L
I
T
I
-
L
--
F
S
D
I
V
-------
G
F
T
R
M
S
N
----
A
L
----
Q
--------
S
Q
G
V
A
E
L
L
N
E
Y
L
G
E
M
T
R
A
V
F
---
E
---
N
Q
----------
G
T
V
D
------
K
F
V
G
D
A
I
M
A
L
Y
G
A
--
P
E
-
E
M
S
P
S
E
Q
V
R
R
A
I
A
T
A
-------------
R
Q
M
L
V
A
L
E
K
L
N
Q
G
W
Q
E
--------
R
GLVGR----
V
P
P
V
R
F
R
C
G
I
H
Q
G
M
A
V
V
--
G
L
F
G
---
S
----
Q
E
R
S
D
F
T
A
---
I
G---
P
S
V
N
I
A
A
R
L
Q
E
A
T
A
--
P
N
S
I
M
-
V
S
A
--
M
V
A
Q
Y
V
P
D
-----------------------------------------------------------------------------------
29
HHSearch
42.93
10%
-53
- C5 -
-
1WC4
2
?
A:
[21-189]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
P
E
P
-
R
L
I
T
I
-
L
--
F
S
D
I
V
-------
G
F
T
R
M
S
N
----
A
L
----
Q
--------
S
Q
G
V
A
E
L
L
N
E
Y
L
G
E
M
T
R
A
V
F
---
E
---
N
Q
----------
G
T
V
D
------
K
F
V
G
D
A
I
M
A
L
Y
G
A
--
P
E
-
E
M
S
P
S
E
Q
V
R
R
A
I
A
T
A
-------------
R
Q
M
L
V
A
L
E
K
L
N
Q
G
W
Q
E
--------
R
GLVGRN
E
--
V
P
P
V
R
F
R
C
G
I
H
Q
G
MAV
V
--
G
L
F
G
---
S
----
Q
E
R
S
D
F
T
A
---
I
G
---
P
S
V
N
I
A
A
R
L
Q
E
A
T
A
--
P
N
S
I
M
-
V
S
A
--
M
V
A
Q
Y
V
P
D
-----------------------------------------------------------------------------------
18
HHSearch
42.36
10%
-49
- C5 -
-
4P2F
19
CYA1_MYCTU
A:
[73-232]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
D
K
Y
-
D
E
A
S
V
-
L
--
F
A
D
I
V
-------
G
F
T
E
R
A
S
----
S
T
----
A
--------
P
A
D
L
V
R
F
L
D
R
L
Y
S
A
F
D
E
L
V
D
---
Q
---
H
G
----------
L
E
K
I
------
K
V
S
G
D
S
Y
M
V
V
S
G
V
--
P
RP
R
---
P
D
H
T
Q
A
L
A
D
F
A
-------------
L
D
M
T
N
----
V
A
A
Q
L
K
D
--------
P
------
R
--
G
N
P
V
P
L
R
V
G
L
A
T
G
P
V
V
A
--
G
V
V
G
---
S
R
R
F
R
Y
-----
D
V
---
W
G
---
D
A
V
N
V
A
S
R
M
E
S
T
D
S
--
V
G
Q
I
Q
-
V
P
D
--
E
V
Y
E
R
L
K
D
-----
D
F
V
L
--------------------------------------------------------------------------
24
HHSearch
40.34
6%
-80
- C5 -
-
4NI2
3
A:
[8-163]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
K
K
F
-
S
N
V
T
M
-
L
--
F
S
D
I
V
-------
G
F
T
A
I
C
S
----
Q
C
----
S
--------
P
L
Q
V
I
T
M
L
N
A
L
Y
T
R
F
D
Q
Q
C
G
---
E
---
L
D
----------
V
Y
K
V
------
E
T
I
G
D
A
Y
C
V
A
G
G
L
--
H
KE
S
---
D
T
H
A
V
Q
I
A
L
M
A
-------------
L
K
M
M
E
----
L
S
D
E
V
M
S
--------
P
------
H
--
G
E
P
I
K
M
R
I
G
L
H
S
G
S
V
F
A
--
G
V
V
G
---
V
KM
P
-
R
Y
----
C
L
---
F
G
---
N
N
V
T
L
A
N
K
F
E
S
C
S
V
--
P
R
K
I
N
-
V
S
P
--
T
T
Y
R
L
L
K
D
-----------------------------------------------------------------------------------
22
HHSearch
39.81
12%
-92
- C5 -
-
1Y11
1
Y1264_MYCTU
A:
[210-377]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
G
A
-
R
Q
V
T
V
-
A
--
F
A
D
L
V
-------
G
F
T
Q
L
G
E
----
V
V
----
S
--------
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-------
P
P
----------
V
W
F
I
------
K
T
I
G
D
A
V
M
L
V
C
P
D
--
P
--
A
---
P
-----
L
L
D
T
V
-------------
L
K
L
V
E
----
V
V
D
T
D
N
--------------------
N
F
P
R
L
R
A
G
-------
V
A
S
G
M
A
V
S
R
-
A
----
G
-----
D
W
---
F
G
---
S
P
V
N
V
A
S
R
V
T
G
V
A
R
--
P
G
A
V
L
-
V
A
D
--
S
V
R
E
A
L
G
D
APEAD
G
F
Q
W
S
F
A
--
G
P
R
R
--
L
R
GIR
G
D
V
----
R
L
F
R
V
R
---
R
G
----------------------------------------
26
HHSearch
38.70
7%
-58
- C5 -
-
1CUL
4
B:
[6-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
S
Y
-
D
C
V
C
V
-
M
--
F
A
S
I
P
-------
D
F
K
E
F
Y
T
----
E
S
DVNK
E
--------
G
L
E
C
L
R
L
L
N
E
I
I
A
D
F
D
D
L
L
S
---
K
PKF
S
G
----------
V
E
K
I
------
K
T
I
G
S
T
Y
M
A
A
T
G
L
SA-ER
Q
---
Y
M
H
I
G
T
M
V
E
F
A
-------------
Y
A
L
V
G
----
K
L
D
A
I
N
K
--------
H
------
S
--
F
N
D
F
K
L
R
V
G
I
N
H
G
P
V
I
A
--
G
V
I
G
---
A
----
Q
KP
Q
Y
-
D
I
---
W
G
---
N
T
V
N
V
A
S
R
M
D
S
T
G
V
--
L
D
K
I
Q
-
V
T
E
--
E
T
S
L
I
L
Q
T
-----------------------------------------------------------------------------------
11
PsiBlast_PDB
38.37
45%
-108
* C3 *
-
2IIR
-
ACKA_THEMA
A:
[99-134]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
S
V
-
L
-
V
D
E
E
V
L
K
A
I
E
E
-----
V
S
P
L
A
P
L
H
-
N
P
A
N
--
L
----
M
G
I
----
K
A
A
M
-----------------------------------------------
23
HHSearch
37.91
12%
-77
- C5 -
-
1Y10
-
Y1264_MYCTU
C:
[210-377]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
G
A
-
R
Q
V
T
V
-
A
--
F
A
D
L
V
-------
G
F
T
Q
L
G
E
----
V
V
----
S
--------
A
E
E
L
G
H
L
A
G
R
L
A
G
L
A
R
D
L
T
A
-------
P
P
----------
V
W
F
I
------
K
T
I
G
D
A
V
M
L
V
C
P
D
--
P
--
A
---
P
-----
L
L
D
T
V
-------------
L
K
L
V
E
----
V
V
D
T
D
N
--------------------
N
F
P
R
L
R
A
G
-------
V
A
S
G
M
A
V
S
R
-
A
----
G
-----
D
W
---
F
G---
S
P
V
N
V
A
S
R
V
T
G
V
A
R
--
P
G
A
V
L
-
V
A
D
--
S
V
R
E
A
L
G
D
AD---
G
F
Q
W
S
F
A
--
G
P
R
R
--
L
RGIR
G
D
V
----
R
L
F
R
V
R
---
R
G
----------------------------------------
32
HHSearch
37.22
7%
-44
* C5 *
-
2WZ1
2
GCYB1_HUMAN
A:
[6-165]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
K
R
Y
-
D
N
V
T
I
-
L
--
F
S
G
I
V
-------
G
F
N
A
F
C
S
----
K
H
ASG----------
A
M
K
I
V
N
L
L
N
D
L
Y
T
R
F
D
T
L
T
D
---
S
---
R
K
-------
N
P
F
V
Y
K
V
------
E
T
V
G
D
K
Y
M
T
V
S
G
L
--
P
EP
C
---
I
H
H
A
R
S
I
C
H
L
A
-------------
L
D
M
M
E
----
I
A
G
Q
V
Q
V
--------
D
---------
G
E
S
V
Q
I
T
I
G
I
H
T
G
E
V
V
T
--
G
V
I
G
---
Q
RM--
P
R
Y
---
C
L
---
F
G
---
N
T
V
N
L
T
S
R
T
E
T
T
G
E
--
K
G
K
I
N
-
V
S
E
--
Y
T
Y
R
C
L
-------------------------------------------------------------------------------------
35
HHSearch
36.44
14%
-170
- C5 -
-
3MR7
-
?
A:
[-1-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
R
-
R
L
C
A
I
-
L
--
A
A
D
M
A
-------
G
Y
S
R
L
M
E
----
R
N
----
E
--------
T
D
V
L
N
R
Q
K
L
Y
R
R
E
L
I
D
P
A
I
A
---
Q
---
A
G
----------
G
Q
I
V
------
K
T
T
G
D
G
M
L
A
R
F
D
------------
T
A
Q
A
A
L
R
C
A
-------------
L
E
I
Q
Q
----
A
M
Q
Q
R
E
E
--------
D
------
T
PR
K
E
R
I
Q
Y
R
I
G
-------
I
N
I
G
D
I
V
L
E
-
D
----
G
-----
D
I
---
F
G---
D
A
V
N
V
A
A
R
L
E
A
I
S
E
--
P
G
A
I
C
-
V
S
D
--
I
V
H
Q
I
T
Q
D
-----
R
V
----------------------------------------------------------------------------
28
HHSearch
35.38
4%
-45
- C5 -
-
4OYZ
-
ADCYA_HUMAN
A:
[36-199]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
D
Y
-
F
D
G
V
L
-
M
--
F
V
D
I
S
-------
G
F
T
A
M
T
E
----
K
F
----
S
SAMYMDR
G
A
E
Q
L
V
E
I
L
N
Y
H
I
S
A
I
V
E
K
V
L
---
I
---
F
G
----------
G
D
I
L
------
K
F
A
G
D
A
L
L
A
L
W
R
V
--
E
RK
Q
L
--
K
N
I
I
T
V
V
I
K
C
S
-------------
L
E
I
H
G
----
L
F
E
T
Q
E
W
--------
E
------
E
--
G
L
D
I
R
V
K
I
G
L
A
A
G
H
I
S
M
--
L
V
F
G
D
ET
H
----
S
-----
H
F
---
L
V
I
G
-
Q
A
V
D
D
V
R
L
A
Q
N
M
A
Q
--
M
N
D
V
I
-
L
S
P
N
--
C
W
Q
L
C
D
------------------------------------------------------------------------------------