@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VPZ2: (2017-11-24 )
MTFQYQVLANQLAHRIYQDELKPHQKLISLRDFARQQGISLSTAKSCYELLEARGLIYVKPKSGYFVVARTPSSPIPDSPDFLSLPRHVSNLELHNQIQKAALQSHLVPLGSIQLTPHFIPVEGLRRSIQRALKNCQPQDFLYCNKQGHEQLRKALSDHWREDGIYIAPEDIFITNGCMPALSLVIQKLTEVGDSILIPTPTYNGHLQLLASLKRQIVEIPADHRGIDLERLESLMQQGLAKVCLMTANYQNPLGYCFSNAEKEKIAELAAKYQCFIIEDDIFGECGYSSERPLPIRYWDREGYVIWCGSVSKSLSSAYRVGWFCLTTKLEHLKLELLVSNIGVNTPLQLGLADFIYSRGYREHLEQLRPNLMRQVEEYRSCILKAFEDIPIALSQPEGGYALWIQLPKSVDSLALYYTAQAQGITVVPGHELTADVRQAIMSLAGWSRQQMQTVS
Atome Classification :
(20 SA)
-----------.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130-------------------.-..------------....140.......150.......160-.--......170........180.......190.......200.......210.......220....--...--230--......-----..-----.-240-----........250.......260.......270.-......280.......------290.------------------------....------------------..300-..-..--.....310.......320...----....330.....-..340.....-..350-......----..---.-360.--......370.......380......-.--390---.--..-......400.......410--------------.--------------......-420.......-------.430--------------------------------...----------.--....440.......450....----------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------M
T
F
Q
Y
Q
V
L
A
N
Q
L
A
H
R
I
Y
Q
D
EL
K
P
H
Q
K
L
I
S
L
R
D
F
A
R
QQGISL
S
T
A
K
S
C
Y
E
L
L
E
AR
G
L
I
Y
V
KPKS
G
Y
F
V
V
A
RTPSSPIPDSP
D
F
L
S
L
P
R
H
V
S
N
L
E
L
H
N
Q
I
Q
K
A
A
L
Q
S
HLVPLG
S
I
Q
LTPHFI
P
V
E
G
L
R
R
S
I
Q
R
A
-------------------
L
-
K
N------------CQPQ
D
F
L
Y
CNKQ
G
H
E
Q
L
R
K
A
L
S
D
H
W
RE-D--G
I
Y
IAPE-
D
I
F
ITNG
C
M
P
A
L
S
L
V
I
Q
K
L
T
EVGD
S
I
L
I
PTPTYN
G
H
L
Q
L
L
A
S
L
K
R
Q
I
V
EIPADHRG--I
D
L
--
E
----
R
L
E
S
L
M
-----
Q
Q
-----
G
-
L
-
A
-----
K
V
C
L
MTANYQN
P
L
G
Y
CFS
N
A
E
K
E
K
I
A
E
L
A
AK
Y
-
Q
C
F
I
I
EDDIFGECGYS------SERP------------------------
L
P
I
R
------------------
Y
W
D---RE-
G
Y
--
V
I
W
CG
S
V
S
K
S
L
S
S
A
Y
R
V
G
W
F
C
----
L
TT
K
L
E
H
L
K
L
E
L
-
L
V
S
NIGVNT
P
-
L
Q
L
---
G
L
A
D
F
I
----
Y
S
---
R
-
G
Y
R
E
--
H
L
E
Q
L
R
P
N
L
M
R
Q
V
E
E
Y
R
S
C
I
L
K
A
F
E
-D--I-----P--
I
A
-LSQPEG
G
Y
A
L
W
I
QLPKSVD--------------
S
--------------
L
A
L
Y
Y
T
-A-QAQ
G
I
T
VV-------PG
H
---------------------------------
E
L
T
----------
A
--
D
V
R
Q
A
I
M
S
LAGWSR
Q
Q
M
QTVS----------------------
10
PsiBlast_PDB
65.95
26%
-81
- C2 -
-
2ZP7
3
LYSN_THET2
C:
[43-360]
------------------------------------------------------------------------------------------------------------------------------
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
-
A
F
V
A
E
W
-------
I
G
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
---
R
E
A
G
Y
PG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
-
F
A
----
V
A
H
P
E
A
L
Q
K
L
V
Q
-
A
K
Q
G
A
D
L
H
T
P
M
L
N
Q
---
M
L
V
H
E
L
----
L
K
---
E
-
G
F
S
E
--
R
L
E
R
V
R
----
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
--
V
-----
P
KE
V
R
-
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
---------------------------------
P
F
F
----------
A
--
N
------------------------------------------
53
Fugue
65.90
20%
8
- C2 -
-
4MGR
1
GABR_BACSU
A:
[2-469]
D
I
T
I
T
L
DRSEQ
A
D
Y
I
Y
Q
Q
I
Y
Q
K
L
K
K
E
I
L
S
R
N
L
L
P
H
S
K
V
P
S
K
R
E
L
A
E
N
L
K
V
S
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
K
G
F
F
V
E
E
L
D
M
F
S
A
E
E
H
P
P
--
F
A
L
P
D
D
L
K
E
I
H
I
D
--------
Q
S
D
W
I
S
F
S
H
M
S
S
D
T
D
H
F
P
I
K
S
W
F
R
C
E
Q
K
A
-------------------
A
-
S
R
------------
S
Y
R
T
L
G
D
M
S
H
P
Q
G
I
Y
E
V
R
A
A
I
T
R
L
I
S
L
-
T
R-
G
V
K
C
R
P
E
-
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
L
L
P
K
E
A
-
V
Y
A
M
E
E
P
G
Y
R
R
M
Y
Q
L
L
K
N
A
G
K
Q
V
K
T
I
M
L
D
E
K
G
--
M
S
I
--
A
----
E
I
T
R
Q
---------------
Q
-
P
-----
D
V
L
V
T
T
P
S
H
Q
F
P
S
G
T
I
M
P
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
P
R
R
Y
I
I
E
D
D
Y
D
S
E
F
T
Y
D
------
V
D
S
I
------------------------
P
A
L
Q
------------------
S
L
D
---
R
F
-
Q
N
--
V
I
Y
M
G
T
F
S
K
S
L
L
P
G
L
R
I
S
Y
M
V
----
L
P
P
E
L
L
R
A
Y
K
Q
R
-
G
Y
D
L
Q
T
C
S
S
L
-
T
Q
L
---
T
L
Q
E
F
I
----
E
S
---
G
-
E
Y
Q
K
--
H
I
K
K
M
K
Q
H
Y
K
E
K
R
E
R
L
I
T
A
L
E
A
E
F
S
-
G
--------
E
--
V
T
-
V
K
G
A
N
A
G
L
H
F
V
T
E
F
D
T
R
R
T
--------------
E
--------------
Q
D
I
L
S
H
-
A
-
A
G
L
Q
L
E
I
F
G
MSRFNL
K
E
N
---------------------------------
K
R
Q
----------
T
--
G
R
P
A
L
I
I
G
F
A
R
L
K
E
E
D
I
Q
E
G
V
Q
R
L
FKAVY--------------
13
PsiBlast_PDB
65.76
26%
-80
- C2 -
-
2ZYJ
2
LYSN_THET2
A:
[43-360]
------------------------------------------------------------------------------------------------------------------------------
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
-
A
F
V
A
E
W
-------
I
G
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
---
R
E
A
G
Y
PG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
-
F
A
----
V
A
H
P
E
A
L
Q
K
L
V
Q
-
A
K
Q
G
A
D
L
H
T
P
M
L
N
Q
---
M
L
V
H
E
L
----
L
K
---
E
-
G
F
S
E
--
R
L
E
R
V
R
----
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
--
V
-----
P
KE
V
R
-
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
---------------------------------
P
F
F
----------
A
--
N
------------------------------------------
12
PsiBlast_PDB
65.76
26%
-85
- C2 -
-
2Z1Y
2
LYSN_THET2
A:
[43-360]
------------------------------------------------------------------------------------------------------------------------------
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
-
A
F
V
A
E
W
-------
I
G
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
---
R
E
A
G
Y
PG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
-
F
A
----
V
A
H
P
E
A
L
Q
K
L
V
Q
-
A
K
Q
G
A
D
L
H
T
P
M
L
N
Q
---
M
L
V
H
E
L
----
L
K
---
E
-
G
F
S
E
--
R
L
E
R
V
R
----
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
--
V
-----
P
KE
V
R
-
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
---------------------------------
P
F
F
----------
A
--
N
------------------------------------------
3
PsiBlast_PDB
64.96
27%
-5
- C2 -
-
3AOW
4
?
A:
[68-419]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
9
PsiBlast_PDB
64.95
26%
-77
- C2 -
-
2EGY
2
LYSN_THET2
A:
[43-360]
------------------------------------------------------------------------------------------------------------------------------
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
-
A
F
V
A
E
W
-------
I
G
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
---
R
E
A
G
Y
PG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
-
F
A
----
V
A
H
P
E
A
L
Q
K
L
V
Q
-
A
K
Q
G
A
D
L
H
T
P
M
L
N
Q
---
M
L
V
H
E
L
----
L
K
---
E
-
G
F
S
E
--
R
L
E
R
V
R
----
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
--
V
-----
P
KE
V
R
-
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
---------------------------------
P
F
F
----------
A
--
N
------------------------------------------
11
PsiBlast_PDB
64.71
26%
-80
- C2 -
-
3CBF
2
LYSN_THET2
A:
[43-360]
------------------------------------------------------------------------------------------------------------------------------
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
-
A
F
V
A
E
W
-------
I
G
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
---
R
E
A
G
Y
PG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
-
F
A
----
V
A
H
P
E
A
L
Q
K
L
V
Q
-
A
K
Q
G
A
D
L
H
T
P
M
L
N
Q
---
M
L
V
H
E
L
----
L
K
---
E
-
G
F
S
E
--
R
L
E
R
V
R
----
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
--
V
-----
P
KE
V
R
-
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
---------------------------------
P
F
F
----------
A
--
N
------------------------------------------
2
PsiBlast_PDB
64.01
27%
-1
- C2 -
-
3AOV
2
?
A:
[68-419]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
6
PsiBlast_PDB
63.88
27%
-4
- C2 -
-
3WX9
7
?
A:
[68-419]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
38
HHSearch
63.80
25%
5
- C2 -
-
3AOW
4
?
A:
[75-447]
------------------------------------------------------------------------------------------------------------------
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
K
R
Y
--
G
I
S
Q
-
D
N
-
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
----
I
L
E
E
K
L
-----
K
E
L
K
S
Q
G
K
-
K
-
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
D
L
C
T
N
V
F
-
G
Q
V
---
V
A
W
R
Y
V
----
D
G
---
G
-
Y
L
E
K
--
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
-
E
--
G
-----
V
--
K
--
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
AFYAHRDVKN
T
M
R
L
N
FTY---------------
V
D
E
----------
D
--
K
I
M
E
G
I
K
R
L
A
E
T
I
K
E
E
L
K
-------------------------
1
PsiBlast_PDB
63.76
27%
-0
- C2 -
-
1X0M
-
?
A:
[48-399]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
5
PsiBlast_PDB
63.71
27%
-2
- C2 -
-
3AV7
5
?
A:
[68-419]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
4
PsiBlast_PDB
63.48
27%
-4
- C2 -
-
3ATH
5
?
A:
[68-419]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
-
K
W
L
G
-
K
--
R
Y
G
I
S
Q
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
I
L
E
E
K
L
K
E
L
K
-----
S
Q
-----
G
-
K
K
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
-
K
M
E
I
-
A
K
Q
S
T
D
L
C
T
N
-
V
F
G
---
Q
V
V
A
W
R
----
Y
V
---
D
-
G
--
G
--
Y
L
E
K
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
--
F
MPE--
G
--
V
K
-
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
---------------------------------
A
F
Y
----------
A
HR
D
V
K
N
T
M
-------------------------------------
41
HHSearch
61.72
25%
9
* C2 *
-
1X0M
-
?
A:
[54-427]
-----------------------------------------------------------------------------------------------------------------
E
T
S
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
I
-------------------
M
-
E
K
------------
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
K
R
Y
--
G
I
S
-
Q
D
N
-
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
I
V
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
--
M
K
V
--
E
----
I
L
E
E
K
L
-----
K
E
L
K
S
Q
G
K
-
K
-
V
-----
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
F
I
V
V
E
D
D
P
Y
G
E
L
R
Y
S
------
G
N
P
E
------------------------
K
K
I
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
----
G
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
D
L
C
T
N
V
F
-
G
Q
V
---
V
A
W
R
Y
V
----
D
G
---
G
-
Y
L
E
K
--
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
-
E
--
G
-----
V
--
K
--
W
T
K
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
--------------
S
--------------
K
K
M
L
E
R
-
A
-
I
K
K
G
V
A
Y
V
-------
P
G
E
AFYAHRDVKN
T
M
R
L
N
FTY---------------
V
D
E
----------
D
--
K
I
M
E
G
I
K
R
L
A
E
T
I
K
E
E
L
K
-------------------------
58
Fugue
60.87
22%
-3
- C2 -
-
4JE5
5
ARO8_YEAST
A:
[5-502]
----------------
T
L
P
E
S
K
D
F
S
Y
L
F
S
D
E
T
N
A
R
K
P
S
-
P
L
K
L
F
Q
D
P
N
I
I
F
L
G
G
G
L
P
L
K
D
Y
F
P
W
D
N
L
S
V
D
S
P
K
P
-----------
P
F
P
Q
G
I
G
A
P
I
D
E
Q
N
C
I
K
Y
T
V
N
K
D
Y
A
D
K
S
A
N
P
-----------
S
N
D
I
P
-------
L
S
R
A
-------------------
L
-
Q
--------------------
Y
G
F
S
A
G
Q
P
E
L
L
N
F
I
R
D
H
T
K
I
I
H
--
D
L
K
Y
K
D
W
-
D
V
L
A
T
A
G
N
T
N
A
W
E
S
T
L
R
V
F
C
N
R
G
D
V
I
L
V
E
A
H
S
F
S
S
S
L
A
S
A
E
A
Q
G
V
I
T
F
P
V
P
I
D
A
D
G
--
I
I
P
--
E
----
K
L
A
K
V
M
-----
E
N
-----
W
-
T
-
P
GAPKP
K
L
L
Y
T
I
P
T
G
Q
N
P
T
G
T
S
I
A
D
H
R
K
E
A
I
Y
K
I
A
Q
K
Y
-
D
F
L
I
V
E
D
E
P
Y
Y
F
L
Q
M
N
PYIKD
L
K
E
R
E
------------------------
K
A
Q
S
SPKQD
H
D
E
F
L
K
S
L
A
N
T
FL
S
L
D
---
T
E
-
G
R
--
V
I
R
M
D
S
F
S
K
V
L
A
P
G
T
R
L
G
W
I
T
----
G
S
S
K
I
L
K
P
Y
L
S
L
-
H
E
M
T
I
Q
A
P
A
G
-
F
T
Q
---
V
L
V
N
A
T
----
L
S
---
R
W
G
Q
K
G
--
Y
L
D
W
L
L
-
G
L
R
H
E
Y
T
L
K
R
D
C
A
I
D
A
L
Y
-
K
--
Y
LPQSD
A
--
F
V
-
I
N
P
P
I
A
G
M
F
F
T
V
N
I
D
A
S
V
H
--------------
P
EFKTKYNSD
P
Y
Q
L
E
Q
S
L
Y
H
K
-
V
-
V
E
R
G
V
L
V
V
-------
P
G
S
---------------------------------
W
F
K
S
E
G
E
T
EPPQP
A
--
E
S
K
E
V
S
N
P
N
I
I
F
F
R
G
T
Y
A
A
V
S
P
E
K
L
T
E
G
L
K
R
L
G
D
T
L
Y
E
E
F
GIS
44
HHSearch
60.34
24%
3
- C2 -
-
2ZC0
3
?
A:
[33-405]
------------------------------------------------------------------------------------------------------------------
G
V
K
L
I
S
L
A
A
G
D
P
D
P
E
L
I
P
R
A
V
L
G
E
I
A
K
E
V
-------------------
L
-
E
K
-------------
E
P
K
S
V
M
Y
T
P
A
N
G
I
P
E
L
R
E
E
L
A
A
F
L
K
K
Y
D
--
H
L
E
V
S
P
E
-
N
I
V
I
T
I
G
G
T
G
A
L
D
L
L
G
R
V
L
I
D
P
G
D
V
V
I
T
E
N
P
S
Y
I
N
T
L
L
A
F
E
Q
L
G
A
K
I
E
G
V
P
V
D
N
D
G
--
M
R
V
--
D
----
L
L
E
E
K
I
-----
K
E
L
K
A
K
G
Q
-
K
-
V
-----
K
L
I
Y
T
I
P
T
G
Q
N
P
M
G
V
T
M
S
M
E
R
R
K
A
L
L
E
I
A
S
K
Y
-
D
L
L
I
I
E
D
T
A
Y
N
F
M
R
Y
E
------
G
G
D
I
------------------------
V
P
L
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
V
A
G
T
L
S
K
V
L
G
T
G
F
R
I
G
W
I
I
----
A
E
G
E
I
L
K
K
V
L
M
Q
K
Q
P
I
D
F
C
A
P
A
I
-
S
Q
Y
---
I
A
L
E
Y
L
----
K
R
---
G
-
Y
F
E
K
Y-
H
L
E
G
A
L
L
G
Y
K
E
K
R
D
I
M
L
K
A
L
E
N
H
L
P
----
N
-----
A
--
E
--
F
T
K
P
I
A
G
M
F
V
M
F
F
L
P
E
G
A
D
--------------
G
--------------
I
S
F
A
N
E
-
L
M
E
R
E
G
V
V
V
V
-------
P
G
K
PFYTDESGKN
A
I
R
L
N
FSR---------------
P
S
K
----------
E
--
E
I
P
I
G
I
K
K
L
A
K
L
Y
K
E
K
F
--------------------------
32
HHSearch
59.88
21%
6
- C2 -
-
4JE5
2
ARO8_YEAST
D:
[37-500]
------------------------------------------------------------------------------------------------------------------
D
P
N
I
I
F
L
G
G
G
L
P
L
K
D
Y
F
P
W
D
N
L
S
V
D
S
P
K
P
PFPQGIGAPIDEQN
C
I
K
Y
T
V
N
K
D
YADKSANPSNDI
P
L
S
R
A
L
Q
Y
G
F
S
A
G
Q
P
E
L
L
N
F
I
R
D
H
T
K
I
I
H
--
D
L
K
Y
K
D
W
-
D
V
L
A
T
A
G
N
T
N
A
W
E
S
T
L
R
V
F
C
N
R
G
D
V
I
L
V
E
A
H
S
F
S
S
S
L
A
S
A
E
A
Q
G
V
I
T
F
P
V
P
I
D
A
D
G
--
I
I
P
--
E
----
K
L
A
K
V
M
-----
E
N
WTPGA
P
-
K
-
P
-----
K
L
L
Y
T
I
P
T
G
Q
N
P
T
G
T
S
I
A
D
H
R
K
E
A
I
Y
K
I
A
Q
K
Y
-
D
F
L
I
V
E
D
E
P
Y
Y
F
L
Q
M
N
------
P
Y
I
K
D
L
K
E
R
E
K
A
Q
S
SPKQD
H
D
E
F
L
K
S
LA
N
T
F
L
------------------
S
L
D
---
T
E
-
G
R
--
V
I
R
M
D
S
F
S
K
V
L
A
P
G
T
R
L
G
W
I
T
----
G
S
S
K
I
L
K
P
Y
L
S
L
H
E
M
T
I
Q
A
P
A
G
F
-
T
Q
V
---
L
V
N
A
T
L
----
S
R
W
G
Q
K
-
G
Y
L
D
--
W
L
L
G
L
R
H
E
Y
T
L
K
R
D
C
A
I
D
A
L
Y
K
Y
L
P
-
Q
SD
A
-----
F
--
V
--
I
N
P
P
I
A
G
M
F
F
T
V
N
I
D
A
S
V
H
PEFKTKYNS
D
P
Y
Q
L
E
--------------
Q
S
L
Y
H
K
-
V
-
V
E
R
G
V
L
V
V
-------
P
G
S
W
F
K
S
E
G
E
TEPPQPAESKEVSNP
N
I
I
F
F
R
G
TYAA
V
S
P
----------
E
--
K
L
T
E
G
L
K
R
L
G
D
T
L
Y
E
E
F
G
-------------------------
7
PsiBlast_PDB
59.52
27%
-13
- C2 -
-
1WST
1
?
A:
[33-373]
-----------------------------------------------------------------------------------------------------------
E
L
L
K
L
V
E
T
S
D
V
I
S
L
A
G
G
L
P
A
P
E
T
F
P
V
E
T
I
K
K
I
A
V
E
V
-------------------
L
-
E
E
------------
H
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
L
A
L
A
-
R
W
M
E
-
K
R
Y
D
I
P
M
S
K
V
-
E
I
M
T
V
A
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
N
P
G
D
P
I
V
V
E
A
P
T
Y
L
A
A
I
Q
A
F
K
Y
Y
D
P
E
F
I
S
I
P
L
D
D
K
G
--
M
R
V
--
D
----
L
L
E
E
K
L
E
E
L
R
K
Q
G
-----
K
-
R
-
V
-----
K
I
V
Y
T
V
S
T
F
Q
N
P
A
G
V
T
M
S
V
D
R
R
K
K
L
L
E
L
A
N
E
Y
-
D
F
L
I
V
E
D
G
P
Y
S
E
L
R
Y
S
------
G
E
P
T
------------------------
P
P
I
K
------------------
H
F
D
---
D
Y
-
G
R
--
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
V
A
A
H
P
H
L
I
R
K
M
E
I
A
K
Q
S
I
----
D
L
C
T
N
T
F
-
G
Q
A
---
I
A
W
K
Y
V
----
E
N
---
G
-
Y
L
D
E
--
H
I
----
P
K
I
I
E
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
-
E
Y-
M
-----
P
EG
V
E
-
W
T
K
P
E
G
G
M
F
V
R
V
T
L
P
E
G
I
D
--------------
T
--------------
K
L
M
M
E
R
-
A
-
V
A
K
G
V
A
Y
V
-------
P
G
E
--------------------------------------------------------------------------------------------
8
PsiBlast_PDB
59.37
27%
-4
- C2 -
-
2ZC0
3
?
A:
[27-371]
----------------------------------------------------------------------------------------------------------
S
E
L
Q
K
K
G
V
K
--
L
I
S
L
A
A
G
D
P
D
P
E
L
I
P
-
R
A
V
L
G
E
I
A
K
E
-------------------
V
-
L
E
------------
K
E
P
K
S
V
M
Y
T
P
A
N
G
I
P
E
L
R
E
E
L
A
A
F
L
K
K
Y
D
--
H
L
E
V
S
P
E
-
N
I
V
I
T
I
G
G
T
G
A
L
D
L
L
G
R
V
L
I
D
P
G
D
V
V
I
T
E
N
P
S
Y
I
N
T
L
L
A
F
E
Q
L
G
A
K
I
E
G
V
P
V
D
N
D
G
MR
V
D
L
L
E
E
----
K
I
K
E
L
K
-----
A
K
-----
G
Q
K
-
V
-----
K
L
I
Y
T
I
P
T
G
Q
N
P
M
G
V
T
M
S
M
E
R
R
K
A
L
L
E
I
A
S
K
Y
-
D
L
L
I
I
E
D
T
A
Y
N
F
M
R
Y
E
------
G
G
D
I
------------------------
V
P
L
K
------------------
A
L
D
---
N
E
-
G
R
--
V
I
V
A
G
T
L
S
K
V
L
G
T
G
F
R
I
G
W
I
I
----
A
E
G
-------
E
I
-
L
K
K
V
L
M
Q
K
Q
P
-
I
D
F
CAP
A
I
S
Q
Y
I
A
L
E
Y
L
K
---
R
-
G
Y
F
E
KY
H
L
E
----
G
A
L
L
G
Y
K
E
K
R
D
I
M
L
K
A
L
E
-
N
H
-
L
-----
P
--
N
A
E
F
T
K
P
I
A
G
M
F
V
M
F
F
L
P
E
G
A
D
--------------
G
--------------
I
S
F
A
N
E
L
M
-
E
R
E
G
V
V
V
V
-------
P
G
K
---------------------------------
P
F
Y
----------
T
--
D
------------------------------------------
43
HHSearch
59.15
20%
-75
- C2 -
-
2ZYJ
2
LYSN_THET2
A:
[30-396]
-----------------------------------------------------------------------------------------------------------------
Q
R
P
G
I
L
S
F
A
G
G
L
P
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
I
-------------------
L
-
R
E
------------
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
A
F
V
A
E
W
I
------
G
--
V
R
P
E
-
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
D
E
G
S
P
V
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
--
P
D
L
--
D
----
A
L
E
E
V
L
-----
K
R
-----
E
-
R
-
P
-----
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
L
V
V
V
E
D
D
A
Y
R
E
L
Y
F
G
------
E
A
R
L
------------------------
P
S
L
F
------------------
E
L
A
R
E
A
G
Y
-
P
G
--
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
F
A
V
----
A
H
P
E
A
L
Q
K
L
V
Q
A
K
Q
G
A
D
L
H
T
P
M
L
-
N
Q
M
---
L
V
H
E
L
L
----
K
E
---
G
-
F
-
S
E
--
R
L
E
R
V
R
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
E
V
P
-
K
--
E
-----
V
--
R
--
Y
T
R
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
--------------
A
--------------
E
G
L
F
R
R
-
A
-
L
E
E
N
V
A
F
V
-------
P
G
G
PFFANGGGEN
T
L
R
L
S
YAT---------------
L
D
R
----------
E
--
G
I
A
E
G
V
R
R
L
G
R
A
L
K
G
L
L
A
L
------------------------