@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQ06: (2017-11-24 )
MPIDTQLTTLFCLIDDFCTDITQNVEQYMLTYGQTKRLRQSKIHASEVITLLLWFHLTGSRNFKAFYLYWAKPFLCSYFTNLPSYSRFIELKAKYAMYFVALIESLKVHSAGIAFIDSTKLAVCHNKRIHQHRVFADSASRGKTSVDWFYGFKLHLICDHIGRLVSYCITTGNVDDRKVLPDLIEHSKLKGKLFGDRGYVGKNWKSRLAEVGVQLITRVKRNMKPQVLAPFDHAVLKKRGIIEAPFKLMKSQFDLEHSRHRSKMGLLTTIFAALTLYALVLVNGYKSGIQQILKPIDLNSA
Atome Classification :
(18 SA)
---------------------------------------------...-----......10-------------------.....--...20.---------------...-------..------..30---.......-.40........50.......-.60.---.......-----70...-------.....80....----....90........100.......110--....--.--...120......------...130.......140.......150......--.160........170----..----....-..---------------.180.....----.---.190.--..-....200.......210.......220....--.--------------------------------------------------------.----------------.---230---.----------------........240.......250...---....260....-.-----------..270....-...280.......290.......300-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------MPI-----DTQ
L
T
T
L
F
-------------------
C
L
I
D
D
--
F
C
T
D
I
T
---------------
Q
N
V
-------
E
Q
------
Y
M
L
T
---YG
Q
T
K
R
L
-
R
Q
SKI
H
A
S
E
V
I
T
L
L
L
W
F
HLT-GSR
N
---
F
K
A
F
Y
L
Y
-----WA
K
P
F
-------
L
C
S
Y
F
TNLP
S
Y
----
S
R
F
I
E
L
K
A
K
Y
A
M
Y
F
V
A
L
I
E
S
L
KVHSA---
G
I
A
F
--I--DS
T
K
--
L
A
V
C
HN------KRI
H
Q
H
R
VFADSASRGK
T
S
V
D
W
F
Y
G
F
K
L
H
L
I
C
--
D
H
-
I
G
R
L
V
S
Y
C
IT------TG----NVD
D
-
R
K
---------------
V
L
P
D
L
I
E
H
S
----K---LK
G
K
L
--FG-DRGYVG
K
N
W
K
S
R
L
A
E
V
G
V
Q
L
I
T
R
V
K
RNMKP
Q
--
V
--------------------------------------------------------L----------------A---P-----F----------------
D
H
A
V
L
K
KRGI
I
E
A
P
F
K
L
M
K
S
Q
FD
L
---
E
H
S
R
H
R
S
KM
G
L
-
L
-----------
T
T
I
F
A
A
L
T
L
-
Y
A
L
V
L
V
N
G
Y
K
S
G
I
Q
Q
I
L
K
PIDLNSA------------------------
12
Fugue
74.04
16%
-
- C1 -
-
4N74
-
?
A:
[264-577]
---------------------TQ
N
T
I
E
T
G
V
G
Y
S
TDV
G
P
R
V
K
A
T
W
K
K
P
W
VNSYG
H
S
L
T
T
S
T
S
-------------------
I
S
A
P
E
--
Q
T
L
D
F
S
---------------
Y
K
M
P
L
LKNPL
E
Q
------
Y
Y
L
V
---
Q
G
G
F
K
R
T
-
D
L
N
D
T
E
S
D
S
T
T
L
V
A
S
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Y
W
D
L
-
S
S
G
W
---
Q
R
A
I
N
L
R
-----
W
S
V
D
H
-------
F
T
Q
G
---------------
E
I
T
N
T
T
M
L
F
Y
P
G
V
V
I
S
R
T
R
S
R
G
---
G
L
M
P
--
T
W
G
D
S
Q
R
--
Y
S
I
D
Y
S
------
N
T
A
W
G
S
D
V
D
F
S
V
F
Q
A
Q
N
V
W
I
R
T
L
Y
D
R
H
R
F
V
T
R
--
G
T
-
L
G
W
I
E
T
-----------------
G
D
F
-
D
K
---------------
V
P
P
D
L
R
F
F
A
----
G
---
G
D
R
S
I
--
R
G
Y
K
Y
K
S
I
A
P
K
Y
A
N
G
D
L
K
G
A
S
K
L
I
T
G
S
L
E
Y
Q
Y
N
V
--
T
-------------------------------------------------------------------------
G
---
K
-----
W
----------------
W
G
A
V
F
V
D
S
G
--
E
A
V
S
D
I
R
R
S
D
F
K
T
G
T
G
V
G
V
R
W
E
S
P
V
G
P
-
I
-----------
K
L
D
F
A
V
P
V
A
-------
D
K
D
E
H
G
L
Q
F
Y
I
G
L
G
P
E
L
--------------------------
15
Fugue
56.51
17%
-25
- C3 -
-
4D08
1
PDE2A_HUMAN
A:
[4-342]
-----------------------------------------D
D
E
Y
T
K
L
-----
L
H
D
G
I
Q
P
V
-------------------
A
A
I
D
S
--
N
F
A
S
F
T
---------------
Y
T
P
-------
R
S
LPEDD
T
S
M
A
I
---
L
S
M
L
Q
D
M
-
N
F
I
N
N
Y
K
I
D
C
P
T
L
A
R
F
C
L
M
V
-
K
K
G
Y
---
R
D
P
P
Y
H
N
-----
W
M
H
A
F
-------
S
V
S
H
F
C
Y
L
L
Y
K
N
LEL
T
N
Y
L
E
D
I
E
I
F
A
L
F
I
S
C
M
C
H
D
L
D
H
R
G
T
---
N
N
S
F
--
Q
--
V
A
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K
S
V
L
A
A
L
Y
S
SEGS
V
M
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H
H
F
A
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A
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A
I
L
N
T
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G
C
N
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F
D
H
F
S
R
K
D
Y
Q
R
M
L
--
D
L
-
M
R
D
I
I
L
A
---------------------------------------
T
D
L
A
H
H
L
----
R
---
I
F
K
D
L
Q
K
M
A
-
E
V
G
Y
D
R
N
N
-
K
Q
H
H
R
L
L
L
C
L
L
M
T
S
C
D
-----------------------------------------------------------------
L
----------------
S
---
D
-----
Q
----------------
T
K
G
W
K
T
T
R
K
I
A
E
L
I
Y
K
E
F
F
S
Q
G
D
L
---
E
K
A
M
G
N
R
P
M
E
M
-
M
DREKAY
I
P
E
L
Q
I
S
F
M
E
H
I
A
M
-
P
I
Y
K
L
L
Q
D
L
F
P
K
A
A
E
L
Y
E
R
V
A
S
N
R
E
H
W
T
K
V
SHKFTIRGLPSNNSLDFLD
14
Fugue
53.63
15%
-16
- C3 -
-
5HC3
-
?
A:
[22-365]
MTNKIAEDPRID
P
R
I
K
A
I
FSGMDL
G
G
G
G
D
V
ES
R
E
A
M
L
E
A
A
S
S
E
E
A
T
A
V
-----
R
D
G
L
R
V
F
L
-------------------
D
A
C
D
N
EE
I
A
P
S
A
G
---------------
L
K
I
-------
E
D
------
Y
E
F
T
S
E
P
D
G
N
I
A
K
I
-
Q
Y
I
R
P
D
S
T
D
K
L
P
C
V
Y
Y
I
H
G
G
-
G
M
Q
S
LSC
Y
Y
G
N
Y
R
A
-----
W
G
K
I
I
A
S
N
G
V
A
V
A
M
V
E
F
R
N
A
L
V
P
----
S
A
L
P
E
V
-
A
P
Y
P
A
G
L
N
D
C
V
S
G
V
K
W
V
A
A
---
H
A
D
E
LG
I
--
D
A
S
R
--
I
I
I
A
G
E
------
S
G
G
G
N
L
T
L
A
A
G
L
R
L
K
Q
E
G
S
Q
D
L
I
Q
G
--
L
Y
A
L
C
--
P
Y
-
I
A
G
S
W
P
S
E
D
S
------
P
S
----
S
T
E
N
-
N
G
---------------
I
L
L
D
L
--
H
N
----
N
---
Q
G
A
M
G
--
Y
G
-
I
E
A
Y
E
M
R
D
P
L
A
W
P
G
F
A
T
E
E
D
V
S
----
G
L
V
P
T
--
F
--------------------------------------------------------
I
----------------
S
---
V
-----
N
----------------
E
C
D
P
L
R
D
E
G
I
-
N
F
Y
R
L
L
L
R
A
G
V
S
------
A
K
C
R
Q
V
M
G
---------------
T
I
H
G
-
T
E
I
-
F
P
I
A
C
P
D
V
S
R
D
T
A
A
S
I
A
N
F
C
K
G
G
--------------------------
17
Fugue
52.88
19%
-15
- C2 -
-
4USR
2
?
A:
[1-357]
---------------------GPAMPPILD
V
I
V
I
G
GG
Q
A
A
L
T
T
A
Y
F
L
R
-----
R
T
S
L
S
Y
L
L
L
D
EQPGPGGAWLHAWDSLR
L
F
S
P
A
--
A
W
S
S
I
A
GWPMPSPTEPGNPT
R
N
D
V
-------
I
D
------
Y
L
R
R
---
Y
E
D
R
Y
Q
F
P
I
Q
R
P
V
R
V
D
T
V
T
R
L
D
D
L
W
R
V
Q
A
G
D
Q
Q
---
W
L
A
R
A
V
I
S
ATGT
W
S
K
P
F
-------
I
-------
P
P
Y
----
E
G
------------
R
E
L
F
Q
G
A
Q
I
H
S
A
HYR
T
P
A
P
--
F
--
A
G
K
R
--
V
M
V
V
G
G
------
G
N
-
S
G
A
Q
V
L
A
E
L
S
S
V
--
S
E
T
L
W
I
T
Q
E
P
P
A
F
L
P
--
D
E
-
V
D
G
R
V
L
F
E
R
A
------
T
A
----
R
W
K
A
-
Q
Q
EGRSIDEPAGGFGDI
V
M
V
P
P
V
R
E
A
----
R
---
E
R
G
V
L
--
V
A
-
E
R
P
F
------
A
R
F
T
E
T
G
V
E
W
A
D
G
R
R
E
N
L
D
A
V
--
I
--------------------------------------------------------
W
----------------
C
---
S
GFRPA
L
----------------
D
H
L
--
R
E
L
G
V
V
E
A
D
G
K
V
Q
V
E
D
T
R
V
---
V
K
Q
P
N
L
W
L
V
G
Y
G
D
-----------
W
T
G
M
A
S
A
T
L
-
I
G
V
T
R
T
--
A
R
S
T
A
D
Q
V
V
Q
A
L
T
A
T
P
-------------------------
1
HHSearch
47.31
14%
0
- C- -
-
1MUS
3
TN5P_ECOLX
A:
[90-382]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
---
L
L
A
I
--
E
--
D
T
T
S
--
L
S
Y
R
H
Q
------
V
A
--------
E
E
L
G
K
L
G
S
I
Q
K
A
S
R
G
W
W
V
H
S
V
L
L
L
E
A
T
T
F
R
T
V
G
L
L
H
Q
E
W
W
M
R
P
D
D
PADA
D
E
K
E
-
S
G
---------------
K
W
L
A
A
A
A
T
S
R
L
R
M
G
SMM
S
N
V
I
A
--
V
C
-
D
R
E
A
D
I
H
A
Y
L
Q
D
K
L
A
H
N
E
R
F
V
V
R
S
K
H
P
R
K
D
V
--
E
SGLY
L
Y
D
H
L
K
N
QPEL
G
G
Y
Q
I
S
I
P
Q
K
G
V
V
D
KRG
K
R
K
N
R
P
A
R
K
A
S
L
S
L
R
S
G
R
I
T
L
KQG
N
I
T
L
N
A
V
L
A
E
E
I
NPPKG
E
T
P
L
K
-----
W
L
L
L
T
SEPVES
L
A
Q
A
L
R
V
I
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
G
A
G
A
---
E
R
Q
R
M
E
K
P
D
N
L
-
E
-----------
R
M
V
S
I
L
S
F
V
-
A
V
R
L
L
Q
L
------------------------------------------
13
Fugue
45.75
18%
-227
- C3 -
-
1G2C
-
?
B:
[480-519]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
--
V
--------------------------------------------------------
F
P
S
--------------
D
---
E
-----
F
----------------
D
A
S
I
S
Q
V
N
E
K
I
N
Q
S
L
A
F
I
R
K
S
D
E
L
---
L
H
N
V
N
A
G
----------------------------------------------------------------------------
16
Fugue
40.92
12%
-106
- C3 -
-
1BIF
1
?
?:
[38-250]
--------------------------------------------------------
C
P
T
L
I
-------------------
V
M
V
G
L
--
P
A
R
--------------------------------------------
G
K
T
Y
I
S
-
K
K
L
T
R
Y
L
N
F
I
G
V
P
T
R
E
F
N
V
G
-
Q
Y
R
R
---
D
M
V
-----------
K
T
Y
-------
K
S
F
E
F
F
L
P
D
N
E
----
E
G
L
K
I
R
K
Q
C
A
L
A
A
L
N
D
V
R
K
F
L
S
E
E
G
G
---
H
V
A
V
--
F
--
D
A
T
-------
N
T
------
T
R
E
R
R
A
M
I
F
N
F
G
E
Q
N
G
-------------------------
Y
K
T
F
F
V
------
E
S
----
I
C
V
D
-
P
E
---------------
V
I
A
A
N
I
V
Q
V
----
K
---
L
G
S
P
--------
D
Y
V
N
R
D
S
D
E
A
T
E
D
F
M
R
R
I
E
C
Y
E
N
---------------------------------------------------------------------------------------------------------------------------------
S
Y
E
S
---
L
D
E
E
Q
D
R
D
L
S
Y
-
I
-----------
K
I
M
D
V
G
Q
S
Y
-
V
V
N
R
V
A
D
H
I
Q
S
R
I
V
Y
Y
L
M
N
I
H
V
T
P
R
------------------------
11
Fugue
31.30
16%
-69
- C3 -
-
5LSJ
-
PMF1_HUMAN
B:
[2-174]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
R
V
K
L
L
D
T
---
M
V
D
T
--
F
--
L
Q
K
L
--
V
A
A
G
S
Y
------
Q
R
F
T
D
C
--
Y
K
C
F
Y
Q
L
Q
P
A
M
T
Q
Q
I
Y
D
K
F
I
A
Q
L
Q
--
T
S
-
I
R
E
E
I
S
D
I
K
E
------
E
G
----
N
L
E
A
V
L
N
---------------
A
L
D
K
I
V
E
E
G
----
K
---
V
R
K
E
P
A-
W
R
-
P
S
G
I
P
E
K
D
L
H
S
V
M
A
P
Y
F
L
Q
Q
R
D
T
L
R
R
H
V
Q
K
Q
E
A
E
--------------------------------------------------------
N
----------------
Q
---
Q
-----
L
----------------
A
D
A
V
L
A
G
R
R
Q
V
E
E
L
Q
L
Q
V
Q
A
Q
Q
Q
A
---
W
Q
A
L
H
R
E
Q
R
E
L
-
V
-----------
A
V
L
R
E
------------------------------------------------------
3
HHSearch
26.31
9%
-135
- C3 -
-
4HLB
-
?
A:
[35-89]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--
Y
A
-
D
K
G
I
R
S
V
D
V
A
A
Y
A
K
G
I
D
I
V
F
V
A
A
D
R
K
M
T
R
A
-------------------------------------------------------------------------------------------------------------
E
F
S
A
I
A
S
R
S
I
R
E
L
K
E
R
F
G
F
---
D
K
D
--------------------------------------------------------------------------------
5
HHSearch
25.87
10%
-59
- C4 -
-
1OGC
-
RBSD_BACSU
B:
[15-36]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
D
L
----
G
H--
T
D
K
I
V
--
I
A
-
D
A
G
L
P
V
P
D
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
24.63
10%
-46
- C4 -
-
1OGD
2
RBSD_BACSU
B:
[15-36]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
D
L
----
G
H--
T
D
K
I
V
--
I
A
-
D
A
G
L
P
V
P
D
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
23.62
15%
-245
* C3 *
-
2E74
1
PETL_MASLA
E:
[1-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
F
G
I
A
V
---
G
I
I
F
--
A
--
I
K
S
I
--
K
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
21.95
18%
-48
- C4 -
-
3P12
1
RBSD_STAA8
B:
[23-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
T
--
I
N
-
D
A
G
M
P
I
P
N
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
18.31
18%
-9
- C4 -
-
3P12
1
RBSD_STAA8
C:
[23-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
L
L
T
--
I
N
-
D
A
G
M
P
I
P
N
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
15.82
12%
-99
* C4 *
-
4A34
1
?
A:
[23-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
E
I
V
--
L
A
-
D
A
N
Y
P
S
A
S
C
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
14.87
12%
-101
- C4 -
-
4A34
-
?
I:
[23-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
E
I
V
--
L
A
-
D
A
N
Y
P
S
A
S
C
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
13.71
18%
0
- C- -
-
4DM0
-
TN5P_ECOLX
A:
[317-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
Y
T
H
R
W
R
I
E
E
F
H
K
A
W
K
T
G
A
G
A
---
E
R
Q
R
M
E
K
P
D
N
L
-
E
-----------
R
M
V
S
I
L
S
F
V
A
V
R
L
L
Q
L
-------------------------------------------
10
Fugue
10.84
29%
0
- C- -
-
1VF5
-
PETL_MASLA
E:
[1-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
L
G
A
V
F
Y
I
V
F
I
A
L
F
F
G
I
A
V
---
G
I
I
F
A
-
I
--
K
S
I
K
--
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------