@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQM0: (2017-11-28 )
MMISESVVDLSRFQFAMTAMYHFLFVPLTLGLAFILAIMETTYVISGKEIYKDMTKFWGKLFGINFALGVTTGLTMEFQFGTNWAYYSHYVGDIFGAPLAIEGLMAFFLESTFIGLFFFGWDRLSKVQHLGVTWLVALGSNMSALWILVANGWMQNPVGAAFNFETMRMELVDFGALIFNPVAQVKFLHTVSAGYVTGAIFVLAISSYYLLKKRDLPFARRSFAIAAIFGLASTLSVILLGDESGYELGDVQKTKLAAIEAEWDTHPAPAPFTLFGAPNHEEMRTDYAVKIPYALGLIATRSTTKEVTGLKDLMQQHEVRIRNGMLAYAELEKLRAGDRSPELLASFEKNQKDLGYGLLLKKYAPNVVDASEQHIQAAVKDTIPNVTALFFSFRAMVASGFLMLLLFILATWAVAKRNAENKPWLLKYALFALPLPWIAAQTGWYVAEGGRQPWSIGEILPTHLSASSLSTGDVWGSILALAAFYTVLLIIEMYLMIKFARLGPSSLHTGKYHFEKQEPKAAVNGEALS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120..-.-....130.......140.......150.......160.......170......--.180.......190.......200.-----......210.......220...----....230.......240.......250.......260.......270.......280.......290......--.300..--.....310......-.320--........330........340.----......350.......360.......370.......380.......390.......400........410..-.....420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MMI
S
E
S
V
V
D
L
S
R
F
Q
F
A
M
T
A
M
Y
H
F
L
F
V
P
L
T
L
G
L
A
F
I
L
A
I
M
E
T
T
Y
V
I
S
G
K
E
I
Y
K
D
M
T
K
F
W
G
K
L
FG
I
N
F
A
LGVTT
G
L
T
M
E
F
QFGTN
W
A
Y
Y
S
H
Y
V
G
D
IFGA
P
L
A
I
E
G
L
M
A
F
F
L
E
S
T
F
I
G
L
F
F
F
G
W
D
R
L
-
S
-
K
V
Q
H
LG
V
T
W
L
VALGSN
M
S
A
L
W
I
L
V
ANGWMQNPVGAAFN
F
E
T
M
R
M
E
L
V
D
F
G
A
L
I
--FNPV
A
Q
V
K
F
L
H
T
VSAG
Y
V
T
G
A
I
F
V
L
-----AIS
S
Y
Y
L
L
KKRDLPF
A
R
R
S
F
A
I
----
A
A
I
F
G
L
A
S
T
L
S
V
I
L
L
GDESGYELGDV
Q
K
T
K
L
A
A
I
E
AEWDTHPAPA
P
F
T
L
FGAP
N
H
E
E
MRT
D
Y
A
V
KI
P
Y
A
L
G
L
I
--ATRST
T
--
K
E
V
T
G
L
K
D
L
M
Q
Q
H
E
-
V
R
I
---RNG
M
L
A
Y
A
E
L
-
E
K
L
RAGDR
S
P
E
L
----
L
A
S
F
EKN
Q
K
D
L
G
Y
G
L
L
L
K
K
YAPNVVD
A
S
E
Q
H
I
Q
A
A
V
K
DTIP
N
V
T
A
L
F
F
S
F
R
A
M
V
A
S
G
-
F
L
M
L
L
L
F
I
L
A
T
W
A
V
-AKRNAENK
P
W
L
L
K
Y
A
L
F
ALP
L
P
W
I
AAQT
G
W
Y
V
AEGGRQPWS
I
G
E
I
L
P
T
HLSASSLS
T
G
D
V
W
G
S
I
L
A
L
A
A
F
Y
T
V
L
L
I
I
E
M
Y
L
M
I
K
F
A
RLGPSSLHTGKYHFEKQEPKAAVNGEALS
16
Fugue
84.64
30%
-113
- C1 -
-
5DOQ
3
?
A:
[1-432]
-
M
N
G
Y
D
P
V
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
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G
V
G
V
P
L
M
I
A
I
A
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W
V
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D
M
H
Y
I
L
L
A
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R
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R
G
F
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V
A
V
G
V
V
T
G
T
A
I
G
L
Q
L
S
L
L
W
P
N
F
M
Q
L
A
G
Q
V
I
S
L
P
L
F
M
E
-
T
F
A
F
F
F
E
A
I
F
L
G
I
Y
L
Y
T
W
D
R
F
-
E
N
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
S
A
S
A
M
F
I
T
M
V
N
A
F
M
N
T
P
Q
G
--
F
E
L
K
N
G
E
L
V
N
I
D
P
I
V
A
M
--
F
N
P
A
M
P
T
K
V
A
H
V
L
A
T
S
Y
M
T
S
A
F
V
L
A
-----
S
I
A
A
W
H
L
W
K
G
N
R
H
I
Y
H
R
K
A
L
H
L
----
T
M
K
T
A
F
I
F
S
V
A
S
A
L
V
G
D
L
S
G
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
E
W
H
F
E
T
-
S
S
H
A
P
L
I
L
F
G
T
L
E
-
E
D
N
E
V
K
Y
A
L
E
I
P
Y
A
L
S
I
L
--
A
H
N
H
P
A
--
A
V
V
T
G
L
N
D
I
P
E
---------------------------
D
E
R
P
P
L
----
Y
--------------------------------------------
I
H
Y
L
F
D
V
M
V
T
I
G
V
F
L
M
V
V
A
A
V
Y
W
L
G
S
I
-
F
R
W
K
W
T
A
K
N
W
F
F
G
L
L
V
A
G
G
P
L
A
M
I
A
I
E
A
G
W
Y
L
A
E
V
G
R
Q
P
W
I
L
R
G
Y
M
K
T
A
E
G
A
T
T
--
S
A
H
V
D
T
M
L
V
L
F
C
L
L
Y
I
V
L
V
I
A
S
A
T
V
L
I
R
M
F
R
R
N
P
-------------------------
6
HHSearch
81.96
28%
-113
- C1 -
-
5DOQ
3
?
A:
[1-432]
-
M
N
G
Y
D
P
V
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
T
I
G
V
G
V
P
L
M
I
A
I
A
Q
W
V
G
I
R
K
N
D
M
H
Y
I
L
L
A
R
R
W
T
R
G
F
V
I
T
V
A
V
G
V
V
T
G
T
A
I
G
L
Q
L
S
L
L
W
P
N
F
M
Q
L
A
G
Q
V
I
S
L
P
L
F
M
E
-
T
F
A
F
F
F
E
A
I
F
L
G
I
Y
L
Y
T
W
D
R
F
-
E
N
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
S
A
S
A
M
F
I
T
M
V
N
A
F
M
N
T
P
Q
G
F
E
L
--
K
N
G
E
L
V
N
I
D
P
I
V
A
M
--
F
N
P
A
M
P
T
K
V
A
H
V
L
A
T
S
Y
M
T
S
A
F
V
L
A
-----
S
I
A
A
W
H
L
W
K
G
N
R
H
I
Y
H
R
K
A
L
H
L
----
T
M
K
T
A
F
I
F
S
V
A
S
A
L
V
G
D
L
S
G
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
E
W
H
F
E
T
S
-
S
H
A
P
L
I
L
F
G
T
L
E
E
D
N
E
-
V
K
Y
A
L
E
I
P
Y
A
L
S
I
L
--
A
H
N
H
P
A
--
A
V
V
T
G
L
N
D
I
P
E
--------------------------------------------------------------------------
D
E
R
P
P
L
Y
-
I
H
Y
L
F
D
V
M
V
T
I
G
-
V
F
L
M
V
V
A
A
V
Y
W
L
G
S
I
F
R
W
K
W
T
A
K
N
W
F
F
G
L
L
V
A
G
G
P
L
A
M
I
A
I
E
A
G
W
Y
L
A
E
V
G
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Q
P
W
I
L
R
G
Y
M
K
T
A
E
G
A
T
T
--
S
A
H
V
D
T
M
L
V
L
F
C
L
L
Y
I
V
L
V
I
A
S
A
T
V
L
I
R
M
F
R
R
N
P
-------------------------
1
PsiBlast_PDB
62.40
31%
-100
- C1 -
-
5DOQ
3
?
A:
[7-313]
-------
V
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
T
I
G
V
G
V
P
L
M
I
A
I
A
Q
W
V
G
I
R
K
N
D
M
H
Y
I
L
L
A
R
R
W
T
R
G
F
V
I
T
V
A
V
G
V
V
T
G
T
A
I
G
L
Q
L
S
L
L
W
P
N
F
M
Q
L
A
G
Q
V
I
S
L
P
L
F
M
E
T
F
-
A
F
F
F
E
A
I
F
L
G
I
Y
L
Y
T
W
D
R
F
E
N
-
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
S
A
S
A
M
F
I
T
M
V
N
A
F
M
N
T
P
Q
G
----
F
E
L
K
N
G
E
L
V
N
I
D
P
I
V
A
M
F
N
P
A
M
P
T
K
V
A
H
V
L
A
T
S
Y
M
T
S
A
F
V
L
A
-----
S
I
A
A
W
H
L
W
K
G
N
R
H
I
Y
H
R
K
A
L
H
L
T
M
K
T
A
F
I
F
S
V
A
S
A
----
L
V
G
D
L
S
G
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
E
W
H
F
E
T
-
S
S
H
A
P
L
I
L
F
G
T
L
E
-
E
D
N
E
V
K
Y
A
L
E
I
P
Y
A
L
S
I
L
--
A
H
N
H
P
A
--
A
V
V
T
G
L
N
D
I
P
E
D
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.35
31%
-99
- C1 -
-
5IR6
3
?
A:
[7-313]
-------
V
L
L
S
R
I
L
T
E
L
T
L
T
V
H
I
I
Y
A
T
I
G
V
G
V
P
L
M
I
A
I
A
Q
W
V
G
I
R
K
N
D
M
H
Y
I
L
L
A
R
R
W
T
R
G
F
V
I
T
V
A
V
G
V
V
T
G
T
A
I
G
L
Q
L
S
L
L
W
P
N
F
M
Q
L
A
G
Q
V
I
S
L
P
L
F
M
E
T
F
-
A
F
F
F
E
A
I
F
L
G
I
Y
L
Y
T
W
D
R
F
E
N
-
Q
K
K
H
L
L
L
L
I
P
V
A
I
G
S
S
A
S
A
M
F
I
T
M
V
N
A
F
M
N
T
P
Q
G
----
F
E
L
K
N
G
E
L
V
N
I
D
P
I
V
A
M
F
N
P
A
M
P
T
K
V
A
H
V
L
A
T
S
Y
M
T
S
A
F
V
L
A
-----
S
I
A
A
W
H
L
W
K
G
N
R
H
I
Y
H
R
K
A
L
H
L
T
M
K
T
A
F
I
F
S
V
A
S
A
----
L
V
G
D
L
S
G
K
F
L
A
E
Y
Q
P
E
K
L
A
A
A
E
W
H
F
E
T
-
S
S
H
A
P
L
I
L
F
G
T
L
E
-
E
D
N
E
V
K
Y
A
L
E
I
P
Y
A
L
S
I
L
--
A
H
N
H
P
A
--
A
V
V
T
G
L
N
D
I
P
E
D
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
37.31
14%
-358
- C1 -
-
2L9U
-
ERBB3_HUMAN
A:
[648-669]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
G
-
L
V
V
I
F
M
M
L
G
G
T
F
L
Y
-
W
R
G
R
---------------------------------------------------------------------------------------------------------------
21
Fugue
35.54
15%
-226
- C1 -
-
5CFF
-
?
A:
[503-589]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
E
F
E
L
R
R
Q
A
S
N
Y
Q
-
L
T
L
---
T
N
T
R
A
T
V
N
I
L
M
E
R
L
K
K
S
D
A
D
V
E
Q
Y
R
A
E
L
E
S
V
Q
L
A
K
G
A
L
E
Q
S
Y
L
V
L
Q
A
D
A
E
Q
L
R
Q
Q
L
T
E
S
Q
D
A
L
N
A
L
R
S
S
S
-------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
28.96
30%
97
- C1 -
-
4WTS
3
?
A:
[96-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
M
W
--
I
D
R
P
D
T
F
D
N
E
M
N
A
L
K
N
I
L
A
N
N
D
-
V
S
N
---
V
D
G
L
I
V
G
S
E
V
---
L
Y
R
G
D
T
D
P
Q
S
----
L
A
N
Y
I
K
Q
V
K
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
27.12
13%
-11
- C1 -
-
2LSE
-
?
A:
[1-101]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
E
E
R
K
K
L
L
E
K
L
E
K
I
L
D
E
V
T
D
G
A
P
---------
D
E
A
R
E
R
I
E
K
L
A
K
D
V
K
D
E
L
--
E
E
G
D
A
K
--
N
M
I
E
K
F
R
D
E
M
E
Q
M
Y
-
K
D
A
---
P
N
A
V
M
E
Q
L
L
E
-
E
I
E
K
L
L
K
K
A
G
S
L
----
V
P
R
G
S
Y
L
E
H
H
H
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
26.74
30%
101
- C1 -
-
4WTR
4
?
A:
[96-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
M
W
--
I
D
R
P
D
T
F
D
N
E
M
N
A
L
K
N
I
L
A
N
N
D
-
V
S
N
---
V
D
G
L
I
V
G
S
E
V
---
L
Y
R
G
D
T
D
P
Q
S
----
L
A
N
Y
I
K
Q
V
K
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
24.87
16%
25
- C1 -
-
3CL3
-
NEMO_HUMAN
D:
[193-251]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
H
S
-
V
Q
V
---
D
Q
L
R
M
Q
G
Q
S
V
-
E
A
A
L
R
M
E
R
Q
A
A
S
----
E
E
K
R
K
L
A
Q
L
Q
V
A
Y
H
Q
L
F
Q
E
Y
D
N
H
I
K
S
S
V
V
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.47
24%
-178
- C1 -
-
5DJQ
-
CCOP1_PSEST
M:
[3-23]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
F
W
S
G
Y
I
A
L
L
T
L
-
G
T
I
V
A
L
F
W
L
-------------------------------------------------------------------------------------------------------------------------
22
Fugue
24.09
11%
20
- C1 -
-
5CWS
-
NUP49_CHATD
D:
[2-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
A
L
Q
Q
E
I
A
K
I
D
E
E
I
Q
K
C
I
R
D
K
E
A
V
D
A
F
L
P
A
H
G
E
Q
L
A
A
I
P
T
D
V
N
F
V
T
R
K
S
E
G
A
H
N
A
L
S
--
S
D
I
L
A
I
D
Q
L
R
E
L
V
K
-
Q
D
A
---
D
N
A
R
L
S
F
K
A
I
-
D
N
L
K
--
L
S
N
A
D
L
----
I
S
Y
F
S
K
T
A
D
E
M
E
E
M
M
K
K
F
E
K
T
I
T
E
I
E
A
H
L
T
G
V
E
A
H
A
M
A
M
Q
N
V
A
V
D
E
R
V
Y
E
L
A
A
V
L
R
E
-
F
E
E
S
I
L
K
V
A
G
V
V
G
G
-
V
K
E
G
V
T
E
L
Q
L
R
D
F
M
-----------------------------------------------------------------------------------------------------
17
Fugue
23.47
27%
26
- C1 -
-
3VOP
4
A27_VACCW
A:
[25-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
L
K
Q
R
L
T
N
L
E
-
K
K
I
---
T
N
V
T
T
K
F
E
Q
I
-
E
K
A
A
K
--
R
N
D
E
V
----
L
F
R
L
E
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
23.10
11%
9
* C1 *
-
5IBW
-
C:
[1-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
R
Y
W
H
D
M
A
-
S
R
I
---
K
N
A
Y
R
N
Y
K
A
F
-
Q
F
-
E
C
S
N
R
I
K
N
A
----
F
R
N
Y
K
L
Y
R
Q
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
19.58
23%
-180
- C1 -
-
1FFT
1
CYOB_ECOLI
A:
[378-403]
----------------------------------------------------
H
S
A
M
L
W
T
I
G
F
I
V
T
F
S
V
G
G
M
T
G
V
L
L
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
18.86
15%
-125
- C1 -
-
1HGV
-
CAPSD_BPH75
A:
[4-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
S
E
V
A
S
Q
V
T
N
Y
I
Q
A
I
A
A
A
G
V
G
V
L
A
L
A
I
G
L
S
A
A
W
K
Y
A
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
18.61
13%
-96
- C1 -
-
5DOQ
2
?
A:
[181-212]
----------------
P
T
K
V
A
H
V
L
A
T
S
Y
M
T
S
A
F
V
L
A
S
I
A
A
W
H
L
W
K
G
N
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
18.00
17%
115
- C1 -
-
1EF1
-
?
C:
[1-89]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
A
S
A
D
L
R
A
D
A
M
A
K
D
R
S
E
E
E
R
T
T
E
A
E
K
N
E
R
V
Q
K
H
L
--
K
A
L
T
S
E
--
L
A
N
A
R
D
E
S
K
K
T
A
N
D
M
I
H
A
ENM
R
L
G
R
D
K
Y
K
T
L
-
R
Q
I
R
Q
G
N
-
T
K
Q
R
----
I
D
E
F
E
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
17.70
25%
125
- C1 -
-
2JPW
-
TNNI3_MOUSE
A:
[1-32]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
D
E
S
S
D
A
A
G
E
P
Q
P
A
P
A
P
V
R
R
R
S
S
A
N
Y
R
A
Y
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
16.39
25%
-201
- C1 -
-
3OMA
1
?
A:
[364-387]
------------------------------------------------------
P
M
L
W
A
L
G
F
L
F
L
F
T
V
G
G
V
T
G
I
V
L
S
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------