@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRB1: (2017-12-01 )
MQLSDFSFELPDELIARYPLETRSASRLLHLDAKGQYHDHMFTDIIDLFEEGDLLVLNDTKVMKARLKGKRTTGGAIEILVERMPNHTTAYCHIKASNSPKAGAELFVGADNIPVIVRGRHENLFVVEFSQPILPVLEQYGQLPIPPYFNREAEEIDTERYQTVFHNPEKIASVAAPTASLHFDEELLAKLDQKGVKKTFVTLHVGAGTFMPVRTDDITNHVMHSEWCDVPQETIDLILATKARGNKVIAVGTTATRALESAAQAHGGKIAAWTGDTQIFIYPGYEFCIVDRLITNFHLPESTLLMLVSALSNRENILAAYEHAVKDRYHFFSYGDAMLIDKLEVLKLKLG
Atome Classification :
(20 SA)
.........10........20........30..-.-..--..--.40.........50........60........-70-........80.--........90........100.......110-------...------....-120.---......130.........140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MQLSDFSFEL
P
D
E
L
I
A
RYPLETRSA
S
R
L
L
H
LDA-K-GQ--Y
H
--
D
H
-
M
F
T
D
I
I
D
L
FEEG
D
L
L
V
LND
T
K
V
M
K
A
R
LKG-KR-TTG
G
A
I
E
I
L
-
V
--
E
RMPNHT
T
A
Y
C
H
I
KASNSPKAG
A
E
L
F
V
GADN-------
I
P
V
------
I
V
RG-RHE
N
---
L
F
V
V
EFS--Q
P
I
L
P
V
L
E
QYGQLPIPPYFNR
E
A
E
E
I
D
T
E
R
Y
Q
T
V
FH
N
P
E
K
I
A
S
VAAPTASLHF
D
E
E
L
L
A
K
L
D
Q
KGV
K
K
T
F
V
T
L
H
VGA
G
T
F
M
P
V
R
T
D
D
I
T
N
H
V
M
H
S
E
WCDV
P
Q
E
T
I
D
L
I
L
ATKARG
N
K
V
I
A
VGT
T
A
T
R
A
L
E
S
A
A
Q
AHG
G
K
I
A
A
W
TGD
T
Q
I
F
I
YPG
Y
E
F
C
I
V
D
R
L
I
T
NFHL
P
E
S
T
L
L
M
L
V
S
A
LSNR
E
N
I
L
A
A
Y
E
H
A
V
K
DR
Y
H
F
FSYG
D
A
M
L
I
D
K
L
E
V
L
K
LKLG
16
HHSearch
73.59
46%
-27
- C5 -
-
1VKY
1
QUEA_THEMA
B:
[16-347]
---
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
L
H
R
-
K
-
T
Q
R
-
I
---
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
D
L
L
V
L
N
V
S
K
V
I
P
A
R
L
Y
A
-
R
K
---
G
A
S
I
E
I
L
-
L
--
I
E
R
L
E
E
G
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
L
V
I
D
E
D
--------
L
S
A
------
V
C
L
G
R
G
E
D
G
---
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------
T
A
G
L
H
F
T
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
G
I
----------------
H
E
E
F
Y
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
V
G
T
T
T
V
R
T
L
E
T
I
A
R
L
P
E
--
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
A
M
L
I
L
----------
12
PsiBlast_CBE
72.85
45%
-26
- C5 -
-
1VKY
1
QUEA_THEMA
B:
[16-346]
---
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
L
H
R
-
K
-
T
Q
--
R
I
--
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
D
L
L
V
L
N
V
S
K
V
I
P
A
R
L
Y
A
-
R
K
---
G
A
S
I
E
I
L
L
I
--
E
R
L
-
E
E
G
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
L
V
I
D
E
D
--------
L
S
A
------
V
C
L
G
-
R
G
E
D
G--
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------
T
A
G
L
H
F
T
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
G
I
----------------
H
E
E
F
Y
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
V
G
T
T
T
V
R
T
L
E
T
I
A
R
L
P
E
Q
E
--
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
A
M
L
I
-----------
15
HHSearch
72.59
46%
-25
- C5 -
-
1VKY
1
QUEA_THEMA
A:
[16-347]
---
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
L
H
R
-
K
-
T
Q
R
-
I
---
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
D
L
L
V
L
N
V
S
K
V
I
P
A
R
L
Y
A
-
R
K
----
A
S
I
E
I
L
-
L
--
I
E
R
L
E
E
G
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
L
V
I
D
E
D
--------
L
S
A
------
V
C
L
G
R
G
E
D
G
---
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------
T
A
G
L
H
F
T
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
V
G
T
T
T
V
R
T
L
E
T
I
A
R
L
P
E
--
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
A
M
L
I
L
----------
1
PsiBlast_PDB
71.57
46%
-5
- C5 -
-
1YY3
-
QUEA_BACSU
A:
[6-341]
-----
F
D
F
E
L
P
E
R
L
I
A
Q
V
P
L
E
Q
R
D
A
S
R
L
M
V
L
D
K
H
T
-
G
E
--
L
T
--
D
S
-
S
F
K
H
I
I
S
F
F
N
E
G
D
C
L
V
L
N
N
T
R
V
L
P
A
R
L
F
G
T
K
E
-
D
T
G
A
K
V
E
L
L
-
L
--
L
K
Q
E
T
G
D
K
W
E
T
L
A
K
P
A
K
R
V
K
K
G
T
V
V
T
F
G
D
G
R
-------
L
K
A
------
I
C
T
E
-
E
L
E
H
G
G
R
K
M
E
F
Q
Y
D
--
G
I
F
Y
E
V
L
E
S
L
G
E
M
P
L
P
P
Y
I
K
E
Q
L
D
--
D
K
E
--------------
A
A
A
P
T
A
G
L
H
F
T
E
E
I
L
Q
Q
L
K
D
K
G
V
Q
I
E
F
I
T
L
H
V
G
L
G
T
F
R
-----------
M
H
A
E
F
Y
Q
M
S
E
E
T
A
A
A
L
N
K
V
R
E
N
G
G
R
I
I
S
V
G
T
T
S
T
R
T
L
E
T
I
A
G
E
H
D
G
Q
F
K
A
S
S
G
W
T
S
I
F
I
Y
P
G
Y
E
F
K
A
I
D
G
M
I
T
N
F
H
L
P
K
S
S
L
I
M
L
V
S
A
L
A
G
R
E
N
I
L
R
A
Y
N
H
A
V
E
E
E
Y
R
F
F
S
F
G
D
A
M
L
I
-----------
36
Fugue
71.06
44%
-56
- C5 -
-
1VKY
1
QUEA_THEMA
A:
[16-347]
---
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
L
H
R
-
K
T
Q
R
--
I
E
--
H
R
-
I
F
R
E
I
I
E
Y
L
E
P
G
D
L
L
V
L
N
V
S
K
V
I
P
A
R
L
Y
A
-
R
K
----
A
S
I
E
I
L
-
L
--
I
E
R
L
E
E
G
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
L
V
I
D
E
D
L
-------
S
A
V
------
C
L
G
R
-
G
E
D
G
---
T
R
I
L
K
F
Q
--
P
---------------------------
Q
D
D
R
L
I
F
E
K
G
---------
T
A
G
L
H
F
T
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
V
G
T
T
T
V
R
T
L
E
T
I
A
R
--
L
P
E
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
A
M
L
I
L
----------
2
PsiBlast_PDB
70.57
45%
-24
- C5 -
-
1VKY
1
QUEA_THEMA
A:
[16-346]
---
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
L
H
R
-
K
-
T
Q
--
R
I
--
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
D
L
L
V
L
N
V
S
K
V
I
P
A
R
L
Y
A
-
R
K
----
A
S
I
E
I
L
L
I
--
E
R
L
-
E
E
G
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
L
V
I
D
E
D
--------
L
S
A
------
V
C
L
G
-
R
G
E
D
G--
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------
T
A
G
L
H
F
T
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
V
G
T
T
T
V
R
T
L
E
T
I
A
R
L
P
E
Q
E
--
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
A
M
L
I
-----------
14
HHSearch
69.11
47%
18
- C5 -
-
1YY3
-
QUEA_BACSU
A:
[4-341]
---
D
L
F
D
F
E
L
P
E
R
L
I
A
Q
V
P
L
E
Q
R
D
A
S
R
L
M
V
L
D
K
-
H
-
T
G
E
-
L
---
T
D
S
S
F
K
H
I
I
S
F
F
N
E
G
D
C
L
V
L
N
N
T
R
V
L
P
A
R
L
F
G
-
T
K
E
D
T
G
A
K
V
E
L
L
-
L
--
L
K
Q
E
T
G
D
K
W
E
T
L
A
K
P
A
K
R
V
K
K
G
T
V
V
T
F
G
D
G
R
-------
L
K
A
------
I
C
T
E
E
L
E
H
G
---
G
R
K
M
E
F
Q
Y
D
G
I
F
Y
E
V
L
E
S
L
G
E
M
P
L
P
P
Y
I
K
E
Q
--
L
D
D
K
E
--------------
A
A
A
P
T
A
G
L
H
F
T
E
E
I
L
Q
Q
L
K
D
K
G
V
Q
I
E
F
I
T
L
H
V
G
L
G
T
F
R
-----------
M
H
A
E
F
Y
Q
M
S
E
E
T
A
A
A
L
N
K
V
R
E
N
G
G
R
I
I
S
V
G
T
T
S
T
R
T
L
E
T
I
A
G
E
H
D
G
Q
F
K
A
S
S
G
W
T
S
I
F
I
Y
P
G
Y
E
F
K
A
I
D
G
M
I
T
N
F
H
L
P
K
S
S
L
I
M
L
V
S
A
L
A
G
R
E
N
I
L
R
A
Y
N
H
A
V
E
E
E
Y
R
F
F
S
F
G
D
A
M
L
I
-----------
3
PsiBlast_PDB
65.58
41%
-22
- C5 -
-
1WDI
1
QUEA_THET2
A:
[4-344]
--
L
E
A
Y
D
Y
H
L
P
P
E
Q
I
A
Q
E
G
V
E
P
R
D
M
A
R
L
M
V
V
Y
R
-
E
-
G
P
--
F
R
V
A
H
K
-
R
V
R
D
L
P
E
F
L
R
P
G
D
V
L
V
F
N
E
S
K
V
I
P
A
R
L
L
A
-
R
K
-
P
T
G
G
K
V
E
I
L
-
L
VR
E
R
------
A
L
L
G
P
A
R
K
A
P
P
G
T
R
L
L
L
L
S
P
K
D
L
-------
A
P
V
PG
L
Q
A
E
V
V
A
V
-
E
E
D
---------------
L
V
A
H
L
E
E
V
G
E
V
P
------------------------------
A
A
P
T
A
G
L
H
F
T
P
E
L
L
E
R
L
R
E
M
G
V
E
L
R
F
L
T
L
H
V
G
P
G
T
F
R
P
----------
M
H
A
E
P
Y
A
I
P
E
E
V
A
E
A
V
N
R
A
K
A
E
G
R
R
V
V
A
V
G
T
T
V
V
R
A
L
E
S
A
Y
R
-
E
G
V
G
V
V
A
G
E
G
E
T
R
L
F
I
R
P
P
Y
T
F
K
V
V
D
A
L
F
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
L
G
R
E
R
T
L
E
A
Y
R
L
A
V
A
E
G
Y
R
F
Y
S
L
G
D
A
M
L
I
-----------
17
HHSearch
65.34
42%
-18
- C5 -
-
1WDI
1
QUEA_THET2
A:
[4-345]
--
L
E
A
Y
D
Y
H
L
P
P
E
Q
I
A
Q
E
G
V
E
P
R
D
M
A
R
L
M
V
V
Y
R
-
E
-
G
P
F
R
V
---
A
H
K
R
V
R
D
L
P
E
F
L
R
P
G
D
V
L
V
F
N
E
S
K
V
I
P
A
R
L
L
A
-
R
K
-
P
T
G
G
K
V
E
I
L
-
L
--
V
R
E
R
------
A
L
L
G
P
A
R
K
A
P
P
G
T
R
L
L
L
L
S
P
K
DLAPVPG
L
Q
A
------
E
V
V
A
V
E
E
D
---------------
L
V
A
H
L
E
E
V
G
E
V
P
------------------------------
A
A
P
T
A
G
L
H
F
T
P
E
L
L
E
R
L
R
E
M
G
V
E
L
R
F
L
T
L
H
V
G
P
G
T
F
R
P
----------
M
H
A
E
P
Y
A
I
P
E
E
V
A
E
A
V
N
R
A
K
A
E
G
R
R
V
V
A
V
G
T
T
V
V
R
A
L
E
S
A
Y
R
E
G
V
G
-
V
V
A
G
E
G
E
T
R
L
F
I
R
P
P
Y
T
F
K
V
V
D
A
L
F
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
L
G
R
E
R
T
L
E
A
Y
R
L
A
V
A
E
G
Y
R
F
Y
S
L
G
D
A
M
L
I
L
----------
24
HHSearch
39.31
14%
-243
- C6 -
-
2WBQ
-
ARGHX_STRVI
A:
[300-321]
------------------------------------------------------
V
L
D
Q
G
D
V
A
F
I
D
N
R
R
A
V
H
G
R
R
A
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
37.22
14%
-218
- C6 -
-
2WBO
1
ARGHX_STRVI
A:
[300-321]
------------------------------------------------------
V
L
D
Q
G
D
V
A
F
I
D
N
R
R
A
V
H
G
R
R
A
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
36.85
33%
-190
- C6 -
-
1NX8
1
CARC_PECCC
B:
[235-255]
------------------------------------------------------
F
W
E
D
G
D
L
L
I
M
D
N
R
R
V
I
H
E
R
E
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
36.68
22%
-253
- C6 -
-
4M23
-
?
B:
[287-309]
------------------------------------------------------
V
A
D
Q
G
D
V
L
F
I
D
N
H
R
A
V
H
G
R
L
P
F
-
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
36.48
22%
-237
- C6 -
-
4NE0
-
?
A:
[307-329]
------------------------------------------------------
V
A
D
Q
G
D
V
L
F
I
D
N
H
R
A
V
H
G
R
L
P
F
-
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
35.74
13%
-216
- C6 -
-
2OG6
-
ASNO_STRCO
A:
[295-317]
------------------------------------------------------
R
L
L
P
G
E
L
A
I
V
D
N
R
V
T
V
H
G
R
T
E
F
-
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
34.76
13%
-201
- C6 -
-
2OG5
-
ASNO_STRCO
A:
[295-317]
------------------------------------------------------
R
L
L
P
G
E
L
A
I
V
D
N
R
V
T
V
H
G
R
T
E
F
-
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
34.39
14%
-152
- C6 -
-
4BG1
1
BODG_HUMAN
A:
[331-352]
------------------------------------------------------
K
M
N
P
G
D
V
I
T
F
D
N
W
R
L
L
H
G
R
R
S
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
34.05
18%
-212
- C6 -
-
1JR7
-
CSID_ECOLI
A:
[262-283]
------------------------------------------------------
P
V
P
V
G
K
F
L
L
I
N
N
L
F
W
L
H
G
R
D
R
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
33.64
14%
-150
- C6 -
-
4C5W
1
BODG_HUMAN
A:
[331-352]
------------------------------------------------------
K
M
N
P
G
D
V
I
T
F
D
N
W
R
L
L
H
G
R
R
S
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
31.86
14%
-167
- C6 -
-
1VZ4
1
ATSK_PSEPU
D:
[248-269]
------------------------------------------------------
R
W
E
A
G
D
V
A
I
W
D
N
R
A
T
Q
H
Y
A
V
D
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------