@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRD9: (2017-12-02 )
MNVLRVPIALRLFLTVLLTTLLIATASLSVLHWTMQKNFAKYVADVEMQKLDRLITNLGNVYTVYHDWGNAIQAQILQIEGTAAPDDYDRLSQWWLRRQYDIAIQQHSFDEHTLINISPDAGTVNKNSIFSDEELRTLEQNLPSEYQPFEGLRFPLSANQFRPSDDKNKSKKGSLKDIETQNGKKRFIALPDRLGLSSRLSLYDAKHQFVVGEPPSSDQMSNRPIMVNSQVVGYLGLKPVLDKEDALSINFFSNQKRYLLLIYALTLLSSLVAALLMATYFKKLIQRLLNATNELTKGNYQHQVVIKRNDELGDLSTQLNHLAEILHQHEESRRQWVADTSHELKTPLAVLQAQIEAMQDGIRKATPEHLDAMMRQVSSLKKLTQDLADLAQADAQQLKCYLSSVNPWEVILQEVENFRPKLEQAGLEIEVEGEGASLLLDRDRFKQIIVNLIGNSIRYTETGGKIHIHTNQTPQEWTLYVDDSPFGLSDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSCKIAQALGGTLSFEHSPLGGLRCVLTFKKQS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300....-...310.......320.......330---------------------------------------------------------------------------------------------------------------------.........340.......350.......360---------...----.--....370.......380.......390......---.400.......410...-..----..420....-----...430-.--.---...---------..440.........450.......460..---.---....470.......480.......490.......500.......510.......520.......530.......540.......550
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNV
L
R
V
P
I
A
L
R
L
F
L
T
V
L
L
T
T
L
L
I
A
T
A
S
L
S
V
L
H
W
T
M
Q
K
N
F
A
K
Y
V
A
D
V
E
M
Q
K
L
D
R
L
I
T
NLG
N
V
Y
T
V
Y
HDWGN
A
I
Q
A
Q
I
L
Q
I
EGTAAP
D
D
Y
D
R
L
S
Q
W
W
L
R
R
QY
D
I
A
I
QQHSFDE
H
T
L
I
N
ISPDAGTVNKNSIF
S
D
E
E
L
R
T
L
E
Q
NLPSEYQPFEGLRFPLSANQFRPSDDKNKSKKGSLKDIETQNG
K
K
R
F
I
AL
P
D
RLGL
S
S
R
L
S
L
YDAKH
Q
F
V
VGEPPSSDQMSNR
P
I
M
VNS
Q
V
V
G
Y
LGLKPVLDKED
A
L
S
I
N
FFSNQ
K
R
Y
L
L
L
I
Y
A
L
T
L
L
S
S
L
V
A
A
L
L
M
A
T
Y
F
K
K
L
I
Q
R
L
L
N
A
T
N
ELTKGNY
Q
H
Q
V
V
I
-KRNDEL
G
D
L
S
T
Q
L
N
H
L
A
E
I
L
H
Q
H
E
-----------------------------------------------------------------------------------------------------------------------
E
S
R
R
Q
W
VADTSHELK
T
P
L
A
V
L
Q
A
Q
I
E
A
M
Q
D
G
----------
I
R
K----A--
T
P
E
H
L
D
A
M
M
R
Q
V
S
S
L
K
K
L
T
Q
D
L
A
D
L
A
Q
A
D
A
Q
Q
L
---
K
C
Y
LSSV
N
P
W
E
V
I
L
Q
E
V
-
E
N
----
F
R
P
K
L
E
QAG-----
L
E
I
E
V
E-G--E---G
A
S
---------
L
L
L--
D
R
D
R
F
K
Q
I
I
V
N
L
IGN
S
I
R
Y
TETG
G
---
K
---
I
H
I
HTNQTP
Q
E
W
T
L
Y
VDDSPFGL
S
D
E
Q
L
S
R
L
G
E
R
F
Y
RVDDSRTRSTGGTGL
G
L
A
L
S
C
K
I
A
Q
ALGG
T
L
S
FEHSPLG
G
L
R
C
V
L
T
FKKQS
30
HHSearch
84.62
25%
-
- C2 -
-
4I5S
-
?
B:
[28-434]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
L
N
Y
R
E
Y
K
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
L
K
V
-
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
MT
D
G
V
L
A
T
D
RSGKITVIN
D
M
A
Q
K
Q
L
NVT
R
E
Q
A
L
E
CNILDILDDDSY
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
RRDEYD
E
F
I
T
L
R
I
R
F
A
L
N
R
R
ESGFIS
G
L
I
A
V
L
H
DA
T
E
Q
E
K
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
D
G
----------
A
L
T
----
E
SV
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
I
D
N
Q
T
S
---
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
-
D
R
----
F
D
Q
I
Q
S
Q
Q
-------
E
I
I
R
D
-
Y
--
P
D
K
-
S
V
W
---------
I
E
I
--
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P
D
G
G
---
K
---
V
T
I
T
M
Q
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
------
T
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
Y
E
-
35
HHSearch
66.42
29%
18
- C2 -
-
5C93
1
?
A:
[10-241]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----------------------------------------------------------------------------------------------------------------------
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
----------
A
W
K
DPE-
V
--
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
---
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
-
D
R
----
F
D
M
I
L
K
K
D
D
NPA
K
Y
Y
T
I
K
R
E
-
F
T
K
R
---
D
L
W
---------
V
E
I
--
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
P
D
G
G
---
V
---
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
A
----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-
33
HHSearch
65.90
25%
1
- C2 -
-
2C2A
1
?
A:
[16-248]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
----------
L
G
E
LDLS
T
--
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
P
D
K
Y
---
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
D
-
38
HHSearch
65.30
29%
13
- C2 -
-
4U7O
1
?
A:
[33-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
----------
A
W
K
DPE-
V
--
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
---
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
-
D
R
----
F
D
M
I
L
K
K
D
D
NPA
K
Y
Y
T
I
K
R
E
-
F
T
K
R
---
D
L
W
---------
V
E
I
--
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
P
D
G
G
---
V
---
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-
36
HHSearch
65.20
25%
13
- C2 -
-
4JAV
1
?
A:
[17-248]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
----------
L
G
E
LD
L
S
T
--
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
P
D
K
Y
---
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
D
-
29
HHSearch
64.18
26%
-3
- C2 -
-
4BIX
-
CPXA_ECOLI
B:
[64-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
----------
S
G
E
--------
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
Q
K
N
----
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
-
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
P
G
-
P
W
P
---------
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
--
T
---
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
--------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
W
L
P
L
Y
-
9
PsiBlast_PDB
61.15
29%
33
- C2 -
-
5LFK
2
?
A:
[54-290]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
P
Q
E
F
L
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
------------
R
S
----
G
--
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
--
L
V
M
S
R
N
Q
Q
K
---
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
---
P
G
P
---------
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
T
-----
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
------
7
PsiBlast_PDB
59.83
29%
18
- C2 -
-
4BIX
1
CPXA_ECOLI
A:
[61-290]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
------------
R
S
----
G
--
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
--
L
V
M
S
R
N
Q
Q
K
---
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
---
P
G
P
---------
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
T
-----
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
--------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
------
19
PsiBlast_PDB
59.62
24%
8
- C2 -
-
2C2A
1
?
A:
[11-240]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
L
K
R
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
----------
L
G
E
LDLS
T
--
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
---------
11
PsiBlast_PDB
59.23
29%
24
- C2 -
-
4CB0
2
CPXA_ECOLI
A:
[57-290]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
F
L
A
A
G
A
S
F
N
Q
M
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
------------
R
S
----
G
--
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
--
L
V
M
S
R
N
Q
Q
K
---
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
-----------
L
D
N
A
A
-----
F
E
A
E
Q
M
-
G
--
K
---
S
L
T
V
NFPPGP
W
P
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
T
-----
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
------
18
PsiBlast_PDB
58.73
24%
21
- C2 -
-
4JAV
1
?
A:
[11-240]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
L
K
R
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
----------
L
G
E
LD
L
S
T
--
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
---------
28
HHSearch
58.62
26%
59
- C2 -
-
4BIV
2
CPXA_ECOLI
A:
[29-295]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
R
K
L
K
N
A
A
D
E
V
A
Q
G
N
L
R
Q
H
P
E
L
E
A
G
P
Q
E
F
L
A
A
G
A
S
F
N
Q
M
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
----------
S
G
--------
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
Q
K
N
----
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
-
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
P
G
-
P
W
P
---------
L
Y
G
--
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
--
T
---
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
W
L
P
L
Y
-
6
PsiBlast_PDB
58.15
29%
34
- C2 -
-
4BIW
2
CPXA_ECOLI
A:
[52-290]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
-
A
G
P
Q
E
F
L
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
------------
R
S
----
G
--
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
--
L
V
M
S
R
N
Q
Q
K
---
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
---
P
G
P
---------
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
T
-----
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
------
17
PsiBlast_PDB
57.83
24%
21
- C2 -
-
3DGE
2
?
A:
[14-240]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
----------
L
G
E
LD
L
S
T
--
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
---------
53
Fugue
57.32
21%
-11
* C2 *
-
1ID0
1
A:
[1-146]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
L
H
P
V
A
P
L
L
D
N
L
T
-
S
A
----
L
N
K
V
Y
Q
R
K
G
-----
V
N
I
S
L
D
I
S
--
P
---
E
I
S
---------
F
V
G
--
E
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
C
L
E
F
V
---
E
---
I
S
A
R
Q
--
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
R
E
V
I
F
D
R
G
Q
R
V
D
T
L
R
----
P
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
Q
Y
E
G
K
I
V
A
G
E
S
M
L
G
G
A
R
M
E
V
I
F
G
R
Q
H
54
Fugue
56.98
20%
-
- C1 -
-
4I5S
-
?
A:
[37-432]
--------------------------------------------------------------------
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
-----------------------------------
K
L
K
V
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
M
T
D
G
V
L
A
T
D
R
-----------------
S
G
K
I
T
V
I
N
D
M
A
Q
K
Q
L
N
--
V
T
R
E
Q
A
L
E
C
N
I
L
D
I
L
D
D
D
S
Y
-
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
R
R
D
E
Y
D
E
F
I
T
L
R
I
R
F
A
L
N
R
--------------------------------------
R
E
S
G
F
I
S
G
L
I
A
V
L
H
D
A
T
E
-
Q
E
K
E
E
-----------------------------------------------------------------------------------------------------------------------
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
D
G
----------
A
L
T
----
E
SV
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
S
H
L
D
-----
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
D
R
F
-
D
Q
----
I
Q
S
Q
-
Q
S
T
E
-----
I
I
R
D
Y
P
-
D
--
K
---
S
V
W
---------
I
E
I
--
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P
D
G
G
---
K
---
V
T
I
T
M
Q
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
-------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
---
16
PsiBlast_PDB
56.97
24%
18
- C2 -
-
4JAU
1
?
A:
[11-240]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
L
K
R
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
Y
N
S
----------
L
G
E
LD
L
S
T
--
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
---------
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
---------
8
PsiBlast_PDB
55.77
29%
22
- C2 -
-
4BIY
1
CPXA_ECOLI
A:
[61-290]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
M
M
-----------------------------------------------------------------------------------------------------------------------
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
------------
R
S
----
G
--
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
--
L
V
M
S
R
N
Q
Q
K
---
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
D
N
----
A
A
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
-
F
--
P
---
P
G
P
---------
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
H
T
-----
K
---
I
E
V
G
F
A
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
---------
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
------
15
PsiBlast_PDB
55.50
24%
28
- C2 -
-
4JAS
1
?
A:
[13-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
R
I
D
-----------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
Y
N
S
----------
L
G
E
LD
L
S
T
--
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
---
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
-
N
A
----
I
K
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
-
S
--
N
VPC
P
V
E
---------
A
Y
I
--
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
K
K
D
A
---
P
D
K
Y
V
K
V
I
L
D
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
---------
1
PsiBlast_PDB
54.65
30%
12
- C2 -
-
5C93
1
?
A:
[10-222]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----------------------------------------------------------------------------------------------------------------------
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
AWKDPEV
A
P
G
F
L
K
----
V
--
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
D
R
F
D
M
I
L
K
K
D
-
D
N
PA
K
Y
Y
T
I
K
R
E
F
T
K
-----
R
D
L
W
V
E
----------------------
I
--
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
P
D
G
G
---
V
---
V
T
C
R
L
L
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
A
----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
--------------------