@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VS22: (2017-12-05 )
MPGTPMTVIPTIDIVDALAAEYAAKSPREILELALSQQGEIAISFSGAEDVVLIDMASRLGKPFRVFSLDTGRLHPETYQFFETVRKHYNINIEICFPDAEAVQSMVNEKGLFSFFKDGHQECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRTEIPVVQADAGFSGPGKQLIKYNPLANWSSADVWSYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNLKK
Atome Classification :
(20 SA)
-----.........--10........---20...-------.....30....--...-.---------------------.-40.....-.-..50-...------.....60---------------------.----.---.......70..--...-...80........90----........100........110-.......120.......130.....---.--.--140-........150.......-160...---...---------------.170.......180.......190.......--------200...-....210......-----.-----220-----.......230.......------240.......-------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----MPGT
P
M
T
V
I
--P
T
I
D
I
V
D
A
L
A
---
A
E
Y
AA-------K
S
P
R
E
I
-
L
E
L
A
--
L
SQ-Q---------------------G-
E
I
A
I
S
FS-G-AE
D
V
-
V
L
I
------
D
M
A
S
RL----------------------G----K---
P
F
R
V
F
SLDTGR--LH
P
-
E
T
Y
Q
F
F
E
T
V
R
K
HY
N
I
----
N
I
E
I
CFP
D
A
E
-
A
V
Q
S
M
V
N
E
K
G
L
-
F
S
F
F
K
D
G
H
Q
E
C
CGIRK
V
Q
P
L
R
K
K
L
A
---
T
--L--D
G
--
W
ITGQRKDQSPGTRTE
I
P
-
V
V
Q
ADA---GFS---------------GPGK
Q
L
I
K
YNPLANWS
S
A
D
V
W
S
Y
I
R
M
MEIPY--------NPLHER-G
F
V
S
IGCEPCTRP-----V-----LPN-----QHEREGR
W
W
W
E
E
A
T
Q
K
E------CGLHAGNLKK-------------------------------
24
PsiBlast_CBE
85.52
64%
5
- C4 -
-
2GOY
1
CYSH_PSEAE
E:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
21
PsiBlast_CBE
85.44
64%
-3
- C4 -
-
2GOY
2
CYSH_PSEAE
H:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
25
PsiBlast_CBE
85.09
64%
-1
- C4 -
-
2GOY
2
CYSH_PSEAE
D:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
23
PsiBlast_CBE
84.86
64%
-3
- C4 -
-
2GOY
2
CYSH_PSEAE
F:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
38
HHSearch
84.78
62%
4
- C4 -
-
2GOY
2
CYSH_PSEAE
D:
[27-249]
-----------------
P
F
D
-
L
P
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
F
G
---------------------
D
-
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
1
PsiBlast_PDB
84.69
64%
8
- C4 -
-
2GOY
1
CYSH_PSEAE
A:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
22
PsiBlast_CBE
84.51
64%
4
- C4 -
-
2GOY
1
CYSH_PSEAE
G:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
26
PsiBlast_CBE
84.42
64%
3
- C4 -
-
2GOY
1
CYSH_PSEAE
C:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
27
PsiBlast_CBE
84.14
64%
-1
- C4 -
-
2GOY
2
CYSH_PSEAE
B:
[32-249]
-----------------------
A
L
A
---
S
S
L
A
D
-------
K
S
P
Q
D
I
-
L
K
A
A
--
F
E
H
-
F
---------------------
G
D
E
L
W
I
S
F
S
-
G
-
A
E
D
V
-
V
L
V
------
D
M
A
W
K
L
----------------------
N
----
R
---
N
V
K
V
F
S
L
D
T
G
R
--
L
H
P
-
E
T
Y
R
F
I
D
Q
V
R
E
H
Y
G
I
----
A
I
D
V
L
S
P
D
P
R
-
L
L
E
P
L
V
K
E
K
G
L
-
F
S
F
Y
R
D
G
H
G
E
C
C
G
I
R
K
I
E
P
L
K
R
K
L
A
---
G
--
V
--
R
A
--
W
A
T
G
Q
R
R
D
Q
S
P
G
T
R
S
Q
V
A
-
V
L
E
I
D
G
---
A
F
S
---------------
T
P
E
K
P
L
Y
K
F
N
P
L
S
S
M
T
S
E
E
V
W
G
Y
I
R
M
L
E
L
P
Y
--------
N
S
L
H
E
R
-
G
Y
I
S
I
G
C
E
P
C
T
R
P
-----
V
-----
L
P
N
-----
Q
H
E
R
E
G
R
W
W
W
E
-----------------------------------------------------
39
HHSearch
59.62
26%
29
- C4 -
-
2OQ2
1
MET16_YEAST
C:
[10-252]
-----------
I
I
V
--
T
Q
E
Q
-
L
D
H
W
N
---
E
Q
L
I
K
L------
E
T
P
Q
E
I
-
I
A
W
S
--
I
V
T
-
F
---------------------
P
-
H
L
F
Q
T
T
A
-
F
-
G
L
T
G
L
V
T
I
------
D
M
L
S
K
L
----------------------
S
----
E
KYY
M
P
E
L
L
F
I
D
T
L
H
--
H
F
P
-
Q
T
L
T
L
K
N
E
I
E
K
K
Y
Y
Q
PKNQ
T
I
H
V
Y
K
P
D
G
C
E
S
E
A
D
F
A
S
K
Y
G
D
-
F
L
-
W
E
K
D
D
D
K
Y
D
Y
L
A
K
V
E
P
A
H
R
A
Y
K
EL-
H
--
I
--
S
A
--
V
F
T
G
R
R
K
S
Q
G
S
-
A
R
S
Q
L
S
-
I
I
E
I
D
E
-----------------------
L
N
G
I
L
K
I
N
P
L
I
N
W
T
F
E
Q
V
K
Q
Y
I
D
A
N
N
V
P
Y
--------
N
E
L
L
D
L
-
G
Y
R
S
I
G
D
Y
H
S
T
Q
P
-----
V
-----
K
E
G
-----
E
D
E
R
A
G
R
W
K
G
K
A
--
K
T
E
------
C
G
I
H
E
A
S
R
---------------------------------
41
HHSearch
58.50
28%
30
- C4 -
-
4BWV
1
?
A:
[34-260]
------------------
I
D
-
I
K
K
C
N
---
E
Q
A
R
D
A
R
L
Q
H
L
E
A
Q
A
L
E
T
-
L
Q
K
T
--
V
E
N
-
F
---------------------
E
-
K
P
A
F
P
C
A
-
L
-
I
A
G
D
V
V
I
L
------
D
L
L
H
R
I
----------------------
G
AFSD
N
---
K
V
K
I
I
F
I
D
T
F
H
--
L
F
P
-
E
T
Y
K
F
L
S
E
V
E
E
R
Y
G
F
----
K
A
H
V
F
H
A
A
D
V
N
N
K
E
A
Y
D
A
K
F
G
S
-
D
L
F
-
I
T
D
I
E
E
Y
D
R
I
C
K
V
E
P
F
S
R
A
L
K
T
L
-
E
--
V
--
D
A
--
M
I
N
G
R
R
R
D
H
G
A
-
E
R
A
H
L
E
-
V
F
E
--------------------------
E
G
K
M
V
K
V
Q
P
L
A
Y
W
E
F
R
D
C
W
D
Y
L
T
K
Y
S
L
P
Y
--------
H
P
L
H
D
Q
-
G
F
P
S
I
G
D
V
Q
S
T
I
P
-----
V
-----
P
R
E
KWFEY
A
G
E
R
S
G
R
---------------------------------------------------------
3
PsiBlast_PDB
57.68
25%
40
- C4 -
-
1SUR
-
CYSH_ECOLI
A:
[8-212]
----------
L
N
E
L
--
P
K
V
D
R
I
L
A
L
A
E
T
N
A
E
L
E
K
-------
L
D
A
E
G
R
-
V
A
W
A
--
L
D
N
-
L
P--------------------
G
-
E
Y
V
L
S
S
S
F
G
-
I
Q
A
A
-
V
S
L
------
H
L
V
N
Q
I
----------------------
R
----
P
---
D
I
P
V
I
L
T
D
T
G
Y
--
L
F
P
-
E
T
Y
R
F
I
D
E
L
T
D
K
L
K
L
----
N
L
K
V
Y
R
A
T
E
S
-
A
A
W
Q
E
A
R
Y
G
K
L
-
W
E
Q
G
V
E
G
I
E
K
Y
N
D
I
N
K
V
E
P
M
N
R
A
L
K
---
E
--
L
--
N
A
Q
T
W
F
A
G
L
R
R
E
Q
S
-
G
S
R
A
N
L
P
-
V
L
A
I
Q
R
---
G
----------------------
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
--------
H
P
L
W
D
E
-
G
Y
L
S
V
G
------------------------------------------------------------------------------------------
46
HHSearch
56.07
24%
31
- C4 -
-
1SUR
-
CYSH_ECOLI
A:
[21-215]
----------------------
A
E
T
N
---
A
E
L
E
K
-------
L
D
A
E
G
R
-
V
A
W
A
--
L
D
N
L
P
---------------------
G
-
E
Y
V
L
S
S
S
-
F
-
G
I
Q
A
A
V
S
L
------
H
L
V
N
Q
I
----------------------
R
----
P
---
D
I
P
V
I
L
T
D
T
G
Y
--
L
F
P
-
E
T
Y
R
F
I
D
E
L
T
D
K
L
K
L
----
N
L
K
V
Y
R
A
T
E
S
-
A
A
W
Q
-
E
A
R
Y
G
K
L
W
E
Q
G
V
E
G
I
E
K
Y
N
D
I
N
K
V
E
P
M
N
R
A
L
K
E
L
-
N
--
A
--
Q
T
--
W
F
A
G
L
R
R
E
Q
S
G
-
S
R
A
N
L
P
-
V
L
A
I
-------------------------
Q
R
G
V
F
K
V
L
P
I
I
D
W
D
N
R
T
I
Y
Q
Y
L
Q
K
H
G
L
K
Y
--------
H
P
L
W
D
E
-
G
Y
L
S
V
G
D
T
H
---------------------------------------------------------------------------------------
30
Fugue
54.46
18%
0
- C4 -
-
3FWK
1
?
A:
[1-308]
------
G
A
M
V
M
R
L
G
--
D
A
A
E
L
C
Y
N
L
T
---
S
S
Y
L
Q
-------
I
A
A
E
S
D
-
S
I
I
A
--
Q
T
Q
-
R
A
I
N
T
T
K
S
I
L
INETFPKWSPLN
G
-
E
I
S
F
S
Y
N
-
G
-
G
K
D
C
-
Q
V
L
L
L
L
Y
L
S
C
L
W
E
Y
Y
----------------------
I
----
V
---
K
L
P
T
V
F
I
D
H
D
D
--
T
F
K
-
T
L
E
N
F
I
E
E
T
S
L
R
Y
S
L
----
S
L
Y
E
S
D
R
D
K
C
-
E
-----
T
M
A
E
A
-
F
E
T
F
L
Q
V
F
P
E
---------------------
T
--
K
A
--
I
V
I
G
I
R
H
T
-
D
P
F
G
E
H
L
K
P
-
I
Q
K
T
D
A
---
N
W
P
-------------------
D
F
Y
R
L
Q
P
L
L
H
W
N
L
A
N
I
W
S
F
L
L
Y
S
N
E
P
I
--------
C
E
L
Y
R
Y
-
G
F
T
S
L
G
N
V
E
E
T
L
P
NPHLR
K
-----
D
K
N
-----
S
T
P
L
K
L
N
F
E
W
E
I
E
N
R
Y
K
H
N
EVT
K
A
E
P
I
P
I
A
D
E
D
L
V
K
I
E
N
L
H
E
D
Y
Y
P
GWYLVDDKLERAGRIKKK
2
PsiBlast_PDB
52.88
30%
21
- C4 -
-
4BWV
1
?
A:
[77-260]
--------------------------------------------------------------------------------------------
A
G
D
V
-
V
I
L
------
D
L
L
H
R
I
----------------------
G
AFSD
N
---
K
V
K
I
I
F
I
D
T
F
H
--
L
F
P
-
E
T
Y
K
F
L
S
E
V
E
E
R
Y
G
F
----
K
A
H
V
F
H
A
A
D
V
-
N
N
K
E
A
Y
D
A
K
F
G
-
S
D
L
F
I
T
D
I
E
E
Y
D
R
I
C
K
V
E
P
F
S
R
A
L
K
---
T
--
L
EV
D
A
--
M
I
N
G
R
R
R
D
H
G
-
A
E
R
A
H
L
E
-
V
F
E
E
G
--------------------------
K
M
V
K
V
Q
P
L
A
Y
W
E
F
R
D
C
W
D
Y
L
T
K
Y
S
L
P
Y
--------
H
P
L
H
D
Q
-
G
F
P
S
I
G
D
V
Q
S
T
I
P
-----
V
PREKW
F
E
Y
-----
A
G
E
R
S
G
R
---------------------------------------------------------
45
HHSearch
51.88
19%
-42
- C4 -
-
2WSI
1
FAD1_YEAST
A:
[54-243]
--------------------------------------------------------------------------------
G
-
E
I
S
F
S
Y
N
-
G
-
G
K
D
C
Q
V
L
L
------
L
L
Y
L
S
C
L
W
E
Y
F
F
I
K
A
Q
N
SFP--------
M
----
Q
---
R
L
P
T
V
F
I
D
Q
E
E
--
T
F
P
-
T
L
E
N
F
V
L
E
T
S
E
R
Y
C
L
----
S
L
Y
E
S
Q
R
--------------------
V
N
M
A
D
A
F
R
D
F
I
K
I
Y
P
---------
E
--
T
--
E
A
--
I
V
I
G
I
R
H
T
D
P
F
-
G
E
A
L
K
P
-
I
Q
R
T
D
S
---
N
W
-------------------
P
D
F
M
R
L
Q
P
L
L
H
W
D
L
T
N
I
W
S
F
L
L
Y
S
N
E
P
I
--------
C
G
L
Y
G
K
-
G
F
T
S
I
G
G
I
N
N
S
L
P
-----
N
-----
P
H
L
-----
R
---------------------------------------------------------------
43
HHSearch
51.03
21%
1
- C4 -
-
3G5A
2
?
B:
[40-240]
-----------------------------------------
N
T
T
K
S
I
L
I
N
E
T
--
F
P
K
-
W
SPLN-----------------
G
-
E
I
S
F
S
Y
N
-
G
-
G
K
D
C
Q
V
L
L
------
L
L
Y
L
S
C
L
W
E
Y
Y
I
V
KLSQSQFDG
K
F
H
R
FP
L
----
T
---
K
L
P
T
V
F
I
D
H
D
D
--
T
F
K
-
T
L
E
N
F
I
E
E
T
S
L
R
Y
S
L
----
S
L
Y
E
S
D
R
D
------------------------
K
C
E
T
M
A
E
--
A
F
E
T
F
L
Q
V
F
P
E
--
T
--
K
A
--
I
V
I
G
I
R
H
T
D
P
F
-
G
E
H
L
K
P
-
I
Q
K
T
D
A
---
N
W
-------------------
P
D
F
Y
R
L
Q
P
L
L
H
W
N
L
A
N
I
W
S
F
L
L
Y
S
N
E
P
I
--------
C
E
L
Y
R
Y
-
G
F
T
S
L
G
N
V
E
E
T
L
P
-----
N
-----
P
H
L
-----
R
---------------------------------------------------------------
32
Fugue
50.42
17%
-40
- C4 -
-
1GPM
2
GUAA_ECOLI
A:
[208-404]
-----------------------
W
T
P
---
A
K
I
I
D
-------
D
A
V
A
R
I
-
R
E
Q
V
----
G
-
D
---------------------
D
-
K
V
I
L
G
L
S
-
G
G
V
D
S
S
-
V
T
A
------
M
L
L
H
R
A
I---------------------
G
----
K
---
N
L
T
C
V
F
V
D
N
G
L
--
L
R
L
N
E
A
E
Q
V
L
D
M
F
G
D
H
F
G
L
----
N
I
V
H
V
P
A
E
D
R
-
F
L
S
A
L
A
------------------
G
E
N
D
P
E
A
K
R
K
I
I
G
---
R
--
V
--
F
V
--
E
V
F
D
E
E
A
L
K
L
E
D
V
K
W
L
A
Q
G
T
I
Y
P
D
V
---
I
E
S
---------------
A
A
K
M
G
L
V
E
--
P
L
K
E
L
F
K
D
E
V
R
K
I
G
L
E
L
G
L
P
Y
--------
D
M
L
Y
R
H
-
P
F
P
---------------------------------------------------------------------------------------------
42
HHSearch
49.71
25%
12
- C4 -
-
1ZUN
1
CYSD_PSESM
A:
[32-231]
---------------------------------
E
-------
A
E
S
I
H
I
-
I
R
E
V
--
A
A
E
-
F
---------------------
D
-
N
P
V
M
L
Y
S
-
I
-
G
K
D
S
A
V
M
L
------
H
L
A
R
K
A
----------------------
F
FPGK
L
---
P
F
P
V
M
H
V
D
T
R
W
--
K
F
Q
-
E
M
Y
R
F
R
D
Q
M
V
E
E
M
G
L
----
D
L
I
T
H
I
N
-----------------------
S
A
K
H
T
D
I
M
K
T
E
G
L
K
Q
A
L
D
K
H
-
G
--
F
--
D
A
--
A
F
G
G
A
R
R
D
E
E
K
-
S
R
A
K
E
R
-
V
Y
S
F
R
D
SK
H
R
W
D
PKN
Q
R
P
E
L
W
NVYNGN
V
N
K
G
E
S
I
R
V
F
P
L
S
N
W
T
E
L
D
I
W
Q
Y
I
Y
L
E
G
I
P
I
--------
V
P
L
Y
F
A
A------------------------------------------------------------------------------------------------
31
Fugue
48.99
14%
24
- C4 -
-
3VRH
1
?
A:
[1-309]
MKCKF
C
S
R
E
A
Y
I
K
I
HY
P
K
M
Y
L
C
E
E
H
F
---
K
E
Y
F
E
-------
R
K
V
S
R
T
-
I
E
R
Y
KL
L
T
K
-
D
---------------------
E
-
R
I
L
V
A
V
S
-
G
G
K
D
S
A
-
V
T
A
------
Y
V
L
K
K
L
----------------------
G
----
Y
---
N
I
E
C
L
H
I
N
L
G
I
SG
Y
S
E
-
K
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K
Q
C
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----
P
L
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-
L
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G
I
G
E
V
K
T
------
R
R
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Y
C
G
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N
K
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---
D
N
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--
D
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--
I
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N
L
D
D
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L
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-
L
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W
N
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---
Y
L
A
K
GGPILP--------
Q
Q
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F
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Y
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VEECPYT
T
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-
V
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E
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E
K
R
P
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T
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-----
F
-----
N
F
V
-----
R
G
Y
L
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K
K
K
L
F
E
P
K
E
C
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------
C
R
M
P
S
S
G
D
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C
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F
C
K
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W
GLK
K
E
I
N
FKVSSTDEEPFG------